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AE?ONIEIAEss

iacaa-iea naiaenoai Aa iaoiaeu eiaeeeaoeee e

eaeaioeoeeaoeee caaieaaaiey iaoa?eae aeey aeea-aiinoeee niaoe
i?ioe-eaeoeea niaoe ea-/aiea

ae?on a?eiia Orthomyxoviridae 3

HN ae?onieiae/aneee a aeeaioien-iie eee aiieioe/aneie iieinoe 7-12
aeiaaiiai eo?eiiai yia?e-iia + ?AA

na?ieiae/aneee ?NE, ?OAA, iaoiae AEo?iaa (?IAA + ?EO) aeey ii?aaeaeaiey
IgM

yeni?ann ?eiioeeoineiiey a ie?anea ii Iaaeianeiio – ooeneiioeeueiua
aeeth/aiey, ethiaianoeaioiay iee?ineiiey n ae?eaeeia?aiaeaaui, ?EO i?,
yeaeo?iiiay iee?ineiiey I?C, a?eii, yioeaoaeeo, iiaaiiiey eae
ineiaeiaiey niua ec iiniaeio-ee, iacee-ioia-/aoee ec ieaeiae iiniaie
?aeiae-iu, ia?iua i?iau nuai?ioee aeeaua (aaeoeeia n oaiia-?aoo?iui
ia?ea?iieio?aia-caeueii), oaeoua (ia?aioa-?aeueii), noaae?eiiiua
aaeoeeiu ec I eee N eee aaiiieiaeaia?iua, aaeoeeia ec ooai-ia aeai-iiai
yieaenaci-ia, aaene-a?eii (iane ae?onia) Ig i?ioe-aia?eiiciue
aei-ii?neee

ae?on ia?a-a?eiia Paramixoviridae 4 ae?onieiae/aneee a ia?ae/iie e
ia?aaeaaaiie eoeueoo?a + ?I, ?AA

na?ieiae/aneee ?I, ?NE, ?CAA

yeni?ann eae i?e a?eiia

I?AE, ?eieou, a?iioeou, eiaeiue e?oi, oa?eiaeou, iiaaiiiee niua ec
iiniaeio-ee, iacee-ioia-/aoee ec ieaeiae iiniaie ?aeiae-iu, ia?iua i?iau
nuai?ioee

?anie-?aoi?-iinei-oeeoe-aeue-iua Paramixoviridae

ae?onieiae/aneee a eoeueoo?a n ia?aciaaieai neiieanoa e neioeeoey + ?I,
?AA

na?ieiae/aneee ?I, ?NE, ?CAA

yeni?ann eae i?e a?eiia

I?AE, iiaaiiiee niua ec iiniaeio-ee, iacee-ioia-/aoee ec ieaeiae
iiniaie ?aeiae-iu, ia?iua i?iau nuai?ioee

aaeaii-ae?o-nu Adenoviri-dae 41 ae?onieiae/aneee a ia?ae/iie e
ia?aaeaaaiie eoeueoo?a + ?I

na?ieiae/aneee ?I, ?NE, ?CAA

I?C, oa?eiaeou, oa-?eiaieiiutheoeaaeueiay eeoi?aaeea, iiaaiiiee,
eiiutheoeaeou, ea?aoi-eiiutheoeaeou(8,19), ino?ua aaii??aae/an-eea
oeenoeou o aeaoae (11,21), aano?iyioa?eou o aeaoae(40,41) niua ec
iiniaeio-ee, iacee-ioia/aoee ec ieaeiae iiniaie ?aeiaeiu, ia?-iua i?iau
nuai?ioee, oaea-eee, ioaeaeyaiia eiiutheoeau, ii/a

ae?on ei?e Paramyxoviridae I ae?onieiae/aneee

na?ieiae/aneee

yeni?ann ?EO ei?ue (eiiutheoeaeo, eeoi?aaeea, nuiue), ei?aaay
iiaaiiiey, iiaeino?ue neea?ice-?othuee iaiyioeaoaeeo, nenoaiiay e?aniay
aie/aiea, ?annayiiue neea?ic e?iaue, ioaeaeyaiia eiiutheoeau, ii/a,
ia?iua i?iau nuai?ioee aeey ei?e eeeai?, nuai?ioea, io o?oia eoni/ee
iicaa, eeeai?, e?iaue, eeioioceu (aeey iaaeeaiiuo), aeoeaiay – aeeaay
aaeoeeia E-16, ianneaiay -i?i-oeaiei?aaie Ig ec ooeeueiie e?iae

ae?on ia?ioeoa Paramyxoviridae IN ae?onieiae/aneee a ia?ae/iie e
ia?aaeaaaiie eoeueoo?ao e a eo?eiii yia?eiia

na?ieiae/aneee ?NE, ?OAA, ?I

yeni?ann ?EO ia?ioeo, ineiaeiaiey (iioi?eo, i?oeo, iai-e?aaoeo,
anaioe/aneee na?iciue iaieiaeo), oea?iyeanoic ieiea?aea o aeaoae i?e
o?ainieaoeaioa?iii iooe nethia, ii/a, eeeai?, nuai?ioea aeeaay aaeoeeia
E-3 Nii-?iaeeioeaa-Ee/ei, o?eaaeoeeia, ian-neaiay – N Ig ec ooeeueiie
e?iae

ae?on e?aniooe Togoviri-dae I

e?aniooa, oa?aoiaaiac

o?eaaeoeeia n RA23/3 a Oaaoeee eio?aia-caeueii a 15 ian e 12 eao, HPV-77
ia?yioa?aeueii

a :

H. sim-plex Herpesviri-dae

2 ae?onineiie/aneee aeaaioneea iiiaiyaea?iua eeaoee Eeiotho-oea n
aioo?eyaea?iuie aeeth/aie-yie a ie?anea ii ?iiaiianeiio-Aeica (
yeni?ann)

ae?onieiae/aneee a eoeueoo?a eeaoie, eo?eiii yia?eiia, aaeuo iuoao + ?I

na?ieiae/aneee ?NE, ?I H.labialis, H. gingivalis (aooiciue noiiaoeo),
ea?aoieiiutheoeaeo, aa?iaoe/aneay yecaia, iaieiaiyioeaoaeeo (1)

aaieoaeueiue aa?ian, aa?ian iiai?iaeaeaiiuo, ?ieue a ?acaeoee ?aea oaeee
iaoee (2) niaea?aeeiia aaceeoe, eeeai?, ia?iua i?iau nuai?ioee

eiaeoeae?iaaiiay aa?iaoe/aneay aae-oeeia Ooaeaae-ca-Iaaan-eiai

H. va-ricella-zoster Herpesviri-dae

ae?onineiie/aneee oaeueoea A?aaai a ie?anea ii Ii?iciao, aioo?eyaea?iua
aeeth/aiey Eeiothooea aao?yiay inia, iiiynu-aathuee aa?ian aaceeoey?iay
aeeaeeinoue

b :

H. cy-tomegalis Herpesviri-dae

oeeoieiae/aneee eeaoee a aeaea niaeiiai aeaca n aioo?eyaea?iu-ie
aeeth/aieyie

na?ieiae/aneee ?EO, EOA

AeIE- aeeaaiinoeea (IOe?) oeeoiiaaaeiae?oniay eioaeoeey (eieethce-iiiay
oeeoiiaaaeey) nethia, ii/a, eee-ai?, n?acu i?aa-iia (iinia?oii)

g : ae?on Yio-oaeia-Aa?? Herpesviri-dae

eioaeoeeiiiue eeioi-iiiiioeeaic (aieaciue Oeeaoiaa), eeioiia Aa?eeooa,
iacioa?eiaaaeueiay ea?oeeiiia

ae?o-nu iniu Poxviridae (ae?on ia-oo?aeueiie iniu, inii-aaeoeeiu,
aaioeiiie iniu ei-?ia, iaacue-yiae iniu, iniu a?ucoiia Cae?a)

iieeiae?on Picornaviridae 3 ae?onieiae/aneee a ia?ae/iie e ia?aaeaaaiie
eoeueoo?ao eea-oie + ?I

na?ieiae/aneee ?I, ?NE eiaiia?aioiay oi?ia, eaaeea oi?iu aac
ia?a-ee/ae, ia?aeeoe/aneee iieeiieaeeo, anaioe-/aneee na?iciue iaieiaeo
oaeaeee, e?iaue, eeeai?, niua ec iiniaeioee, ia?iua i?iau nuai?ioee
oaeoay iieeaae-oeeia Niee, aaeoeeia iieeiieaeeoiay ia?i?aeueiay aeeaay
oeiia 1,2, 3(Naaeia)

Eienaee A, Eienaee A, ANII Picornaviridae 23

6

31 ae?onieiae/aneee ca?aaeaiea ia?ae/iie e ia?aaeaaaiie eoeueoo? eeaoie,
iuoae- ninoieia + ?I

na?ieiae/aneee ?I, ?NE aa?iaiaeia,

anaioe/aneee ieiea?-aeeo

eeoa/iua eioaeoeee, I?C, anaioe/aneee na-?iciue iaieiaeo,
iiee-iieaeeoiiiaeiaiua, iiaaiiiey oaeaeee, e?iaue, eeeai?, niua ec
iiniaeioee, ia?iua i?iau nuai?ioee

?ioaae?onu Reoviridae

yeni?ann yeaeo?iiiay iee?ineiiey, eiioiiay ye iee?ineiiey,
?aaeeieiioiiue aiaeec, EOA

na?ieiae/aneee ?I, ?NE, ?OAA ?ioaae?oniue aano?iyioa?eo eni?aaeiaiey,
ia?iua i?iau nuai?ioee

ae?on aaoainoaa Rabdoviri-dae

iinia?oii ae?onineiie/aneee aeeth/aiey Aaaaoa-Iaa?e a ie?anea ii
Naeea?no

ae?onieiae/aneee a iicaa iuoae + ?EOi?

?EOi?, EOA

i?eaeeciaiiay ae?onineiie/aneee ?EOi?

ae?onieiae/aneee aioo?eiicaiaia ca?aaeaiea iuoae nethiie aieueiiai +
?EOi? aaoainoai iica, iiae/aethno-iua aeaeacu, iacee-ioia/aoee ec
aeiiieaiia (iinia?oii), ni neea?,nethia, eeeai?, neaciay aeeaeeinoue

eiaeoeae?iaaiiay eoeueoo-?aeueiay aioe?aae/aneay aaeoeeia ec ooaiia
Aioeiai 32/107,

aioe?aae/aneee Ig

ae?on aaceeoey?ii-ai noi-iaoeoa Rabdoviri-dae

ae?onieiae/aneee a eoeueoo?a eeaoie + ?I

na?ieiae/aneee ?NE, ?I aaceeoey?iue noiiaoeo iacie ec caaa, niaea?aeeiia
aaceeoe

a?ai-ae?o-nu Togaviri-dae, Bunya-viridae, Reoviridae, Arenaviri-dae,
Flavi-viridae, Rabdoviri-dae

ae?onieiae/aneee a eo?eiii yia?eiia, ia?ae/iuo eoeueoo?ao eeaoie, iuoao
i?e aioo?e-iicaiaii ca?aaeaiee yioeaoaeeou, yioeaoaeiieaeeou, nenoaiiua
eeoi?aaeee (aeaeoay, Aeaiaa e ae?.), aaii??aae/aneea eeoi?aaeee n
eaieeey?ioieneeicii

ae?on aanai-ia-eao-iaai eeauaaiai yioeaoaeeoa Togaviri-dae

ae?onieiae/aneee a eo?eiii yia?eiia, ia?ae/iuo e ia?aaeaaaiuo eoeueoo?ao
eeaoie, iuoao i?e aioo?e-iicaiaii ca?aaeaiee

na?ieiae/aneee ?I, ?NE, ?OAA n aoneiuie y?eo?ioeeoaie aanaiia-eaoiee
eeauaaie yioeaoaeeo e?iaue, eeeai?, ia?iua i?iau nuai?ioee, iica
oia?oaai aeoeaiay-

eiaeoeae?iaaiiayoi?iaeeiii eoeue-oo?aeueiay aaeoeeia i?ioea eeauaai-ai
yioea-oaeeoa

iannea-iay- Ig i?ioea eeauaai-ai yioea-oaeeoa Ig i?ioea eeauaai-ai
yioea-oaeeoa

AAIAOEOU

oei aaiaoeoa naiaenoai ae?oaea iacaaiey iooue ca?aaeaiey EOI
i?ioeeaeoeea ae?oaea naaaeaiey

A Picornaviridae

(Yioa?iae?on 72) aieaciue Aioeeia, yieaeaie/aneee aaiaoeo aeeiaioa?-iue
IgM e IAV eoeueoo?aeueiay eiaeoeae?iaaiiay oi?iaeeiii aaeoeeia ec
iaiei/ae ae?ona, ianneaiay N Ig ec ooeeueiie e?iae aeaeoooiua e
aacaeaeoooiua oi?iu, ia ia?aoiaeeo a o?iie/aneoth oi?io, ia iaeaaeaao
oa?aoiaaiiui aeaenoaeai, eieoa ia?eiae 25-30 aeiae

B (Hep)adenovi-ridae nuai?ioi/iue aaiaoeo, oi?eoeaaay aeaeoooa
ia?aioa-?aeueiue, iieiaie, o?ainiea-oeaioa?iue, i?e ?iaeao HbS, HbE, IgM
e HbC, IOe? ieaciaiiay aaeoeeia ec IbS Aa, aaiiieiaeaia?iua aaeoeeiu (
ae?iaeaeaaay, aaeoi?iay) a aeaea ae?eiiia (/anoeoeu Aeaeia),
noa?e/aneea, o?oa-/aoua oi?iu, iaiei/ee (HbS), eieoa ia?eiae 60-90
aeiae, 10 % ia?aoiae a o?iie/aneoth oi?io

C Flaviviridae

ia?aioa-?aeueiue, iieiaie, o?ainiea-oeaioa?iue, i?e ?iaeao IgM e HCV,
IOe?

ia?aoiae a o?iie/aneoth oi?io, oee??ic, eioaa?aoeaiay oi?ia – ia?ae/iue
?ae ia/aie, eiiaaea n IAV

D

ia?aioa-?aeueiue, iieiaie, o?ainiea-oeaioa?iue, i?e ?iaeao HbS, HbE,
IgM aeaeueoa-ae?ono

aeaoaeoiue AeIE-niaea?aeauee, ?aciiiaeaaony n IAV, iaeaaaynue a aai
iaiei/ee, ieacuaaao iae-?ioece?othuaa aicaeaenoaea (ia/aii/iay eiia)

E

aeeiaioa?-iue, /a?ac aiaeo io?eoeao ?acoeueoaou ia A B C D, IOe?

o aa?aiaiiuo aeaiuei ii/a/ii-ia/aii/iue neiae?ii aei aaiaoo?ee,
eaoaeueiinoue, aueeaeuoe, i?aaeaeaa?aiaiiua ?iaeu

F

aeeiaioa?-iue

AeIE-niaea?aeauee

G

iioiae ia HCV

AAEOA?EIEIAEss

iacaaiey aaeoa?ee iacaaiey caaieaaaiee iaoa?eae aeey aeeaaiinoeee
enoi/iee ei-oaeoeee, iooue iaoiaeu aeeaaiinoeee i?ioeeaeoeea ea/aiea

S. aureus oo?oieoeu, ea?aoieoeu, aanoeannu, oeaaiiia,

nainen,

iiaaiiiee,

oiiceeeo, aiaeia,

inoaiieaeeo,

o?ao?eo, oeen-oeo

eiiutheoeaeo o iiai?iae-aeaiiuo,

yiaeiea?aeeo,

ieuaaua oieneeieioae-oeee

ianoeou

iaieiaeo aiieiia ioaeaeyaiia

e?iaue

iie?ioa, i?iiuaiua aiaeu a?iioia

ioaeaeyaiia ec caaa

e?iaue, aiieiia ioaeaeyaiia

ii/a

ioaeaeyaiia eiiutheoeau

e?iaue

?aioiua iannu, i?iiuaiua aiaeu aeaeoaeea, oaeaeee

iieiei

eeeai? aieueiie, iineoaeue,

aicaeooii-eaiaeueiue aaeoa?eieiae/aneee (ii ii?oiei-ae/aneei,
oeie-oi?eaeueiui eoeueoo?aeueiui, aeioei naieno-aai, oaaioeie?i-aaiea
aioo?e aeaea)

noaoeeieieeiaue aaeoa?eioaa

aeey ino?uo caaieaaaiee: i?ioeainoaoeeieieeiaue Ig /aeiaa-/aneee,

i?ioeainoaoeeieieeiaay ieacia /aeiaa/aneay

aeey o?iie/aneeo: noaoeeieieeiaue aiaoienei, oaeoay aaeoeeia,
aooiaae-oeeia

S pyogenes

na?ia?oiia A,

b-aaiieec aiieiua ii-?aaeaiey ei-aee: no?aioi-aea?iee, aan-oeannu,
oeaa-iiia, eiia-oeai, ?iaea,

aiaeia, nea?eaoeia, nainen, ?aaiaoeci aiieiia ioaeaeyaiia

ioaeaeyaiia ec caaa

e?iaue

nuai?ioea

aaeoa?eieiae/aneee (ii ii?oiei-ae/aneei, oeie-oi?eaeueiui
eoeueoo?aeueiui, aeioei, Aa naie-noaai)

aeey ?aaiaoecia na?iaeeaaiinoeea (Ao e no?aioiee-ceiai e
aeaeo?i-ieaeaca)

S agalactiae

A

iaieiaeo e nainen iiai-?iaeaeaiiuo e?iaue, eeeai?

aaeoa?eieiae/aneee

S faecalis

D

N, iinooe?o?-ae/aneea aiieiua ain-iaeaiey ee-oa/ieea e a?thoiie
ii-einoe

aeeooociue aeiia?oeiiao?eo,

caaieaaaiey ii/aiieiaie nenoaiu iiaaiiiey,

nainen

aiieiia ioaeaeyaiia eeoa/ieea e a?thoiie iieinoe

ii/a, e?iaue

ii/a, ioaeaeyaiia ec aeaaaeeua

iie?ioa, i?iiua-iua aiaeu a?iioia

e?iaue

aaeoa?eieiae/aneee

S sanguis

H

a-aaiieec o?iieinainen (naioe/aneee ycaaiiue yiaeiea?aeeo) e?iaue

aaeoa?eieiae/aneee

S pneumoniae e?oiiciay iiaaiiiey,

ioeou,

eiiutheoeaeo,

iieco/ay ycaa ?iaiaeoeu,

aeae?eioeenoe-ou,

iaieiaeou o aeaoae,

nainen,

yiaeiea?aeeou,

aiaeia iie?ioa

aiie

ioaeaeyaiia eiiutheoeau, ycau

eeeai?

e?iaue

e?iaue

iacie ec caaa aicaeooii-ea-iaeueiue, aaiaoiaaiiue ?aaeoeey iaaooa-iey
eainoe (Iae-oaeueaea) ?aaeoeey iee?iaaaethoeia-oeee (Nyaeia) – iuoea
aioo?e-a?thoeiii iie-?ioo, yennoaeao niaoeaatho n nuai?ioeie

noaoeeieieee, no?aioieieee, eeaaneaeeu, eeoa/iua ia-ei/ee, iiaaii-eieee,
neia-aiieiay iaei/-ea,eaiaeeaeu, aaiioeeueiua, aaeoa?ieaeu, aaeeiiaeeu,
iaioieieee, iaioino?aioi-eieee, ooci-aaeoa?ee, N perfringens nainen
e?iaue

iinaa ia naoa?-iue aoeueii, n?aaeo Eeoo-Oa-?ioeoee,

iee?ineiiey iac-ea e?iae, auaea-eaiea /enoie eoeueoo?u ia e?iayiie aaa?,
ii?aaeaeaiea /oa-noaeoaeueiinoe e aioeaeioeeai, ii?aaeaeaiea ae-aea
iee?ii?aa-iecia

N meningitidis yieaeaie/an-eee oea?aa?i-nieiaeueiue iaieiaeo,

iacioa?eiaeo

nainen iacie ec iiniaeioee, e?iaue, eeeai? aicaeooii-ea-iaeueiue io
aieueiiai eee iineoaey aaeoa?eieiae/aneee ia nuai?i-oi/iue IIA e IIA

aaeoa?eineiie-/aneee ii A?aio, iaoeeaiiaie neiueth – iacaaa?-oaiiue
oaaioee-oic oeie/aneay iieenaoa?eaeiay aaeoeeia

N gonorrhoeae aiii?ay aeaineay ino-?ay: o?ao?eo aanoeaoeeo, aa?oieeieo

o?iie/aneay: yiaeioea?aeoeeoyiaeiiao?eo, aaeiaeneo, iioi?eo

ineiaeiaiey: aiaiaoi/iay aa?aiaiiinoue, aanieiaeea, iiiia?o?eo,
yiaeiea?aeeo

ioaeneay ino-?ay: o?ao?eo o?iie/aneay: i?inoaoeo, yieaeeaeeieo

ineiaeiaiey: i?inoaoeo, yi-aeiea?aeeo, ii-iia?o?eo

aoeueaiaaae-ieo o aeaai-/ae,

aeaii?ay nainen i?e EAeN

aiieiia ioaeaeyaiia aeaaaeeua, oaeee iaoee

iacie ec oea?ae-eaeueiiai eaiaea, ioieoeey caaeiaai naiaea aeaaaeeua,
ii/a

aiieiia ioaeaey-aiia o?ao?u

yyeoeyo, i?inoa-oe/aneee nie, ii-/a

ioaeaeyaiia aoeueau

ioaeaeyaiia

e?iaue

iieiaie

eiioaeoii-auoiaie ino?ay aiii?ay – aaeoa?eineiie-/aneee,
aaeoa?e-ieiae/aneee

o?iie/aneay – na?ieiae/aneee (?NE Ai?aea-AEaiao, ?EO),
aaeoa?eieiae/aneee

oaeoay aiiiaaeoeeia

Haemophilus influenzae

H parainfluen-zae I?C, a?ii-oeo, ea?ei-aeo,

iaieiaeou, iiaaiiiee,

ioeo,

nainen neecue ec AAeI

eeeai?

iie?ioa aicaeooii-ea-iaeueiue aaeoa?eieiae/aneee

Haemophilus ducrey iyaeee oaie? ioaeaeyaiia yca iieiaie
iee?ineiie/an-eee (noaeea ?ua, ?aeuenu)

Haemophilus aegipticus yieaeaie/an-eee eiiuthe-oeaeo ioaeaeyaiia
eiiutheoeau

iee?ineiie/an-eee, aaeoa?ei-eiae/aneee

Haemophilus vaginalis (gardnerella) ianiaoeeoe/aneea aaaeieou
ioaeaeyaiia

iee?ineiie/an-eee- eeaoee iein-eiai yieoaeey n aaeaaceae aa?aeia-?aee,

aaeoa?eieiae/aneee- iee?iay?i-oeeu

Bordetella pertussis (1,2,3),

B parapertussis (14),

B bronhiseptica eieetho caaeiaaeioi/iue oaiiii, eaoeaaua ieanoeiee
aicaeooii-ea-iaeueiue io aieueiiai eee iineoaey aaeoa?eieiae/aneee

na?ieiae/aneee ?A, ?NE, ?IAA oaeoay ei?ioneo-ey?iay eieethoiay aaeoeeia
(?aaeoi-aaiia iayooaeoea-ia), AEAeN, AE, aaneeaoi/iay eie-ethoiay
aaeoeeia (EO, OAA) aioeoiene/aneee i?ioeaieieetho-iue Ig /aeiaa/an-eee
aeey aeaoae aei 2 eao

Pseudomonas eruginosa aiieii-ainia-eeoaeueiua in-eiaeiaiey o iaeiaiauo,
oe?o?ae/an-eeo, o?ieiae-/aneeo aieue-iuo aiie, e?iaue, ioaeaeyaiia ?ai,
ii/a, iie?ioa yeciaaiiia ca?aaeaiea a noaoeeiia?a aaeoa?eieiae/aneee
iinaa ia IIA, e?iayiie aaa?

neiaaiieiue aae-oa?eioaa, i?ioeaineiaaiie-iue aioeoiene/an-eee Ig
(aeiii?neee)

Yersinia pestis oi?iu /oiu :

eiaeii-aoaiiiay,

eaai/iay,

eeoa/iay

ioieoao, ioaeaey-aiia ec aoaiia,

iie?ioa,

oaeaeee,

i?e anao oi?iao e?iaue aieueiie /aei-aae e a?ucoiu (e?unu, non-eeee,
no?ee), ia?aiin/eee aeioe

o?ainienneaiue-eiaeii-ao-iiiay, eii-oaeoiue- eiae-ii-aoaiiiay,
aicaeooii-eaiaeueiue-eaai/iay, aeeiaioa?iue-eeoa/iay aaeoa?eieiae/aneee

iee?ineiie/aneee

yeni?ann ?EO

i?iaa n oaaaie

i?iaa ia aaeuo iuoao e ii?n-eeo naeieao aeeaay aaeoeeia E. V.

Yersinia pseudotu-berculosis inaaaeiooaa?eoeac, nea?ea-oeiiiiaeiaiay
eeoi?aaeea, eeoa/iay oi?ia (yioa-?eo, aano?iyi-oa?eo, aiiai-aeeoeeo),
naioe-ei-oeoieaeiay oi?ia, aeae-oooiay, non-oaaiay e?iaue, oaeaeee,
ii/a, neecue ec iiniaeioee a?ucoiu, eioee, niaaee, ei?iau

aeeiaioa?-iue aaeoa?eieiae/aneee – N?aaea Yiaei i?e 28iN

na?ieiae/aneee – ?A, ?IAA

Yersinia enterocolitica eeoa/iue ea?neieic, nonoaaiay oi?ia, aaia-oeo,
aaia?aee-ciaaiiay oi?-ia n aunuia-ieyie e?iaue, oaeaeee, ii/a naeiuee,
ei?iau, niaaee, eioee, a?ucoiu

aeeiaioa?-iue aaeoa?eieiae/aneee – N?aaea Yiaei i?e 28iN

na?ieiae/aneee – ?A, ?IAA

Francisella tularensis oi?iu ooey-?aiee :

aoaiiiay,

aiaeiicii-aoaiiiay,

aeaciay,

eaai/iay,

eeoa/iay,

naioe/aneay

ioieoao, ioaeaey-aiia ec aoaiia,

ioaeaeyaiia eiiu-theoeau

iie?ioa,

oaeaeee,

i?e anao oi?iao e?iaue iuoe-iieaa-ee, e?unu, oiiyee, cae-oeu, aiaeyiua
e?unu

o?ainienneaiue (eeaue, eiia?u, neai-ie), eiioaeo-iue, ay?iaai-iue,
aeeiai-oa?iue na?ieiae/aneee – e?iayii-eaiaeue-iay ?aaeoeey
aa-aethoeiaoeee ia noaeea n ooey?a-ieeiui aeeaaiin-oeeoiii, ni 2
ia-aeaee ?A, ?IAA

aeea?aieiae/an-eee – i?iaa n oo-ey?eiii (acaanue oaeouo aaeoa?ee a 3 %
aeeoea?eia) aeeaay aaeoeeia Yeue-aa?oa-Aaeneiai

Brucella melitensis

B abortus

B suis

B ovis

B canis

B neotomae a?ooeaeac aaiieoeueoo?a, o?eiieoeueoo?a, aeeeeoeueoo?a,
eaeoieoeueoo?a, yennoaeao i?e ao?-neoao, eeeai?, ieaeieoeueoo?a
iinia?oii eicu, iaoeu, ei?iau, naeiuee,

aeeiaioa?-iue, eiioaeo-iue, ay?iaai-iue na?ieiae/aneee – i?eaioe?iai/iay
?A ia noaeea Oaaeaeaeueniia, ?A ?aeoa, ?IAA, iiniii-oaaioee-oa?iay i?iaa
Oo?eoa?a, ?EO, i?e o?iie/aneie oi?ia ?aaeoeey Eoiana aeey iaiieiue Ao

aeea?aieiae/an-eee – i?iaa Ath?-ia n a?ooeaeeeiii (oeeueo?ao 3
ia-aeaeueiie aoeueii-iie eoeueoo?u) aeeaay aaeoeeia ec ooaiia B abortus
ii yieae iieacaieyi

oaeoay aaeoeeia

Bacillus anthracis neae?neay ycaa oi?iu :

eiaeiay,

eeoa/iay,

eaai/iay, naioe/aneay

ioaeaeyaiia io ea?aoieoea, no?oi

?aioiua iannu, oaeaeee

iie?ioa

e?iaue i?e anao E?N, I?N, eioaaee, naeiuee

eiioaeoiue, aeeiaioa?-iue, aicaeoo-ii-eaiaeueiue iee?ineiie/an-eee – ii
A?aio, ?EOi?

aaeoa?eieiae/aneee – ia IIA, IIA

aeea?aieiae/an-eee – i?iaa n aio?aeneiii

ca?ieiae/aneee – ?aaeoeey oa?ii-eieueoeai?aoeeieoaoeee ii Aneiee aeeaay
aaneainoeue-iay aaeoeeia NOE Ig neae?aycaaiiue eioaaeeiue

Pseudomonas mallei cai e?iaue, aiieiia ioaeaeyaiia yca, aanoeannia,
aiie-iua auaeaeaiey neecenouo eioaaee, in-eu, ioeu, aa?aethaeu

eiioaeoiue, aeeiaioa?-iue aaeoa?eieiae/aneee

na?ieiae/aneee – ?NE

Pseudomonas pseudomallei iaeeieaeic e?iaue, aiieiia ioaeaeyaiia yca,
aanoeannia, aiie-iua auaeaeaiey neecenouo a?ucoiu, eioee, niaa-ee
eiioaeoiue, aeeiaioa?-iue aaeoa?eieiae/aneee

na?ieiae/aneee – ?NE

OA?AEOA?ENOEEA
AAEOA?EE

iacaaiea ii?oieiaey, Aa

eoeueoo?aeueiua naienoaa eeanneoeeaoeey oaeoi?u iaoiaaiiinoe

noaoeei-eieee A?+, nii?, aeaooeeia, eainoe iao

ia IIA eieiiee n ieaiaioii, ia IIA aeeooociia iiiooiaiea, ia e?iayiii
aaa?a n ciiaie aaiieeca eee aac

iauea (yeeeiniua )Aa n eiaeae e ii/a/iie oeaiueth ii iaee/eth
ieacii-eiaaoeacu (i), ay?iaiie (a), e aia-y?iaiie (ai) oa?iai-oaoeee
iaiieoa

S. aureus

i+ a+ ai+

S. epidermidis

i- a+/- ai-

S. saprophiti-cus

i- a+/- ai-

iaioeaeiaeeeai oiene/aneia aeaenoaea ia oaaioeeou, iaacaeaeaeeaaao eo,

oaeoiaaay eeneioa iia?aaeaeaao eeioioeeou, nieaeaao au?aaioeo Ao

aaeie A eiiiiiaio eeaoi/iie noaiee, ianiaoeeoe/anee naycuaaaony n
aeiiaiii NI3 IgG, e yoiio eiiieaeno i?eniaaeeiy-aony eiiieaiaio,
aeaenoaoao ia oaaioeeoic, o?iiaioeeou

oa?iaiou iaoiaaiiinoe

ieaciieiaaoeaca (aeaeaoeie?iaaiea e?iee/ueae ieaciu), oea?e-iieecei,
aeaeo?iieaeaca, eaoeeoiaeooaeaca, AeIEaca,?IEaca

oieneiu (aaiieecei, eaeeioeeaeei, yenoieeaoeaiue oienei – neiae?ii
Eaeaea, yioa?ioieneiu A B C D F-ieuaaua io?aa-eaiey, yecioienei
oiene/aneiai oiea)

iiiaeanoaaiiay eaea?noaaiiay onoie/eainoue R-ieacieaeu, aaooa-eaeoaiaca

aeey EIN aaeaaceiu e eeaoeai i?a-ia, iieeia?ai

no?aioi-eieee a?+, nii?, aeaooeeia iao, oieueei S pneumoniae a
i?-aaiecia ia?acoao eainoeo

naoa?iue aoeueii i?eaeiiii-i?enoaii/iue ?ino, e?iayiie aaa? iaeeea
eiei-iee n ciiaie aaiieeca

yeeeiniua Aa n yiaeiea?aeii, ii/eaie, eiaeae, NO yeieiaey, iaee/ea I e S
aaiieeceia, oea-?eiieeceia, Aa e eoeueoo?aeueiua naie-noaa (?ino ia
n?aaeao n aeae/ueth, iieiea n iaoeeaiiaie neiueth, uaei/iuo n?aaeao) –
13 na?ia?oii, 23 aeiaa?a oa?iaiou iaoiaaiiinoe : aeaeo?iieaeaca,
oea?eiieecei, AeIEaca, ?IEaca

oieneiu : I e S no?aioieeceiu, eaeeioeeaeei, y?eo?iaaiiue oienei

I-Aa iieenaoa?eae eeaoi/iie noaiee

iiaaii-eiee a?+, eaioeaoiaeaeiua aeeiei-eieee, nii?, aeaooeeia iao, a
i?aaiecia eainoea

oi/a/iua eieiiee ia nuai-?ioi/iii aaa?a, e?iayiii aaa?a ciiu
iicaeaiaiey, ?ino ia naoa?iii IIA

84 Aa oeia ii Aa naienoaai (o /aeiaaea /aua aucuaatho caaieaaaiey 1, 2,
3 oeiu, 3 iaeaieaa ae?oeaioai aaiieeoe/aneea, eaeeioeeoioiene/aneea
oaeoi?u, eainoea, yiaeioieneiu (ie?iaaiiia aeaenoaea, aaii??aae/aneea
caaieaaaiey)

N menin-gitidis a?- aiaiaeaeiua aeeieieie-ee, nii?, aeaooeeia iao, a
i?aaiecia eaino-ea

iaeeea eieiiee ia 25 % nuai?ioi/iuo n?aaeao i?e 37i N

7 Aa oeiia (A B C D X Y Z) aeeooa?aioee?otho n Branhamella catar-rhalis
ii ?inoo ia n?aaeao (iaieiaieiee ia ?anoao ia IIA) e oaiia?aoo?iiio
ia?ea?o aaeaaceaiay aeoeaiinoue

iieenaoa?eaeiay iee?ieainoea

yiaeioienei (iooio?iauaaaony io ee, a e?iaioie, ii?aaeaao ninoaeu,
aaii??aae/aneea aunuiaiey ia eiaea e neecenouo)

N gonor-rhoeae a?- aiaiaeaeiua aeeieieie-ee, nii?, aeaooeeia iao, a
i?aaiecia eainoea

iaeeea eieiiee ia 25 % nuai?ioi/iuo n?aaeao

aaeaaceaiay aeoeaiinoue

iieenaoa?eaeiay iee?ieainoea

yiaeioienei

aaiioeeue-iua aaeoa-?ee a?- iaeeea eieeiaaeoa?ee, nii?, aeaooeeia iao, a
i?aaiecia eainoea

e?iayiie aaa? n oaeoi?aie O e V

iieenaoa?eaeiay eainoea, oeeeeinoaoe/aneee oaeoi? – aaeaacey aianoa n
oeia?eyie,

yiaeioienei

ai?aeaeeu a?- iaeeea eieeiaaeoa?ee, nii?, aeaooeeia iao,

n?aaea Ai?aea-AEaiao (e?iaue, ea?oioaeue, aeeoea?ei), ii-ei/ii-e?iayiie
aaa?, EOA, eieiiee a aeaea eaiaeae ?oooe aeeooa?aioee?otho ii nei?inoe
?inoa, iaee/eth o?aacu, oe?iceiacu, ?inoo ia n?aaea Iaaeianeiai, Aa
no?oeoo?a ieee,

oeeaiaioiciue aaiaaaethoeiei OAA – naycue iaaeaeo iee?iaaie,
eieiiecaoeey

eieethoiue oienei EO – (yecioienei) aaeie, o?aeoeey A ii?aaeaeyao
iaoiaaiac caaieaaaiey (noeioee?oao eeioioeeoic, aenoaieinaineaeeecaoeey,
einoeeiaeoeaaoeey, i?ioaeoeaiay aeoeaiinoue), o?aeoeey A i?ee?aieyao EO
e ?aoeaioi?ai eeaoie

Pseudomo-nas eruginosa a?- iaei/ea, iiaeaeaeiay, nii? iao, eiiaaea
ia?acoao eainoeiiiaeiaiia a-ai

ia IIA e?oaeua neecenoua eieiiee neiacaeaiiai oeaaoa (ieioeeaiei) n
caiaoii aeanieia (o?eiaoeeaiei), ia IIA aeeooocii-iooyuee ?ino

yecioienei

oa?iaiou : iae?iieieaeaca

neeceiiaeiaiia a-ai aeey aaeaacee e caueou

iiiaeanoaaiiay eaea?noaaiiay onoie/eainoue (R-ieacieaea)

Yersinia pestis, Yersinia pseudotu-berculosis, Yersinia enterocolitica
a?- iaeeay iaieaeiay iaei/-ea n aeiiey?iui ie?aoe-aaieai, nii?,
aeaooeeia iao o Yersinia pestis, a i?a-ia eainoea

ia IIA eieiiee a R-oi?ia a aeaea “e?oaeaaiuo ieaoi/eia”, ia IIA ieaiea
ni “noaeaeoeoaie” ii aeioeie/aneei naienoaai eainoeueiua Aa V, W –
onoie/eainoue e oaaioeeoico

oa?iaiou – oea?eiieecei, ieaciieiaaoeaca

ianoeoeeiu

oieneiu – eaoaeueiue “iuoeiue” oienei – ea?aeeioiene/aneia aeaenoaea,
eaieeey?ioiene/aneia aeaenoaea – iiiaeanoaaiiua e?iaieceeyiey ia eiaea e
ai aioo?aiieo i?aaiao

Francisella tularensis a?- iaeeea eieeiaaeoa?ee nii?, aeaooeeia iao,
iaaeiay eainoea, iieeii?oiu

ye/iua, aetheici-e?iayiua N?aaeu n aeiaaaeaieai oeenoeia i?e 37i N

aaeaaceaiinoue

eiaaceaiinoue

yiaeioienei

a?ooeaeeu a?- iaeeea eieeiaaeoa?ee e ei?ioeea iaei/ee nii?, aeaooeeia
iao,

iaeeea eieiiee ia nuai-?ioi/ii-aeaeno?iciii aaa?a, e?iayiii aaa?a (5 %
iaa/ueae e?iae), ia/aii/iuo n?aaeao, ia aeeaeeeo – aeeooocii-iooyuee
?ino ii ?inoo ia n?aaeao n e?aneoaeyie (ooe-nei, oeiiei), niinia-iinoe
ia?aciauaaoue H2S, aaaethoeiaoeee iiiiniaoeeoe/anee-ie nuai?ioeaie,
/oanoaeoaeueiinoe e oaao eiaaceaiinoue

yiaeioienei

oa?iaiou o?aaca (eaieeey?ioiene/aneia aeaenoaea – ioneieea ieaoeaiou)

Bacillus anthracis a?+ e?oiiua nii?iia?aco-thuea iaei/ee, aeaooeeia iao,
anoue eainoea

ia IIA eieiiee a R-oi?ia a aeaea “a?eau eueaa”, ia IIA i?eaeiiiue ?ino –
“eiii/ae aaou” aeeooa?aioee?otho n Bacillus subtilis, Bacillus
mesentericus, Bacillus cereus, o e iie ii?oieiae/anee noiaeiu ioa/iue
oaeoi? (“i?ioaeoeaiue Aa”)

eaoaeueiue (“iuoeiue”) oienei

iieeiaioeaeiay eainoea (oeene?oao ia eeaoeao)

Pseudomo-nas mallei, Pseudomo-nas pseudo-mallei a?- iaeeea iaei/ee nii?
iao, aeaooeee anoue o Pseudo-onas mallei

N?aaeu n aeiaaaeaieai 4-5 % aeeoea?eia, ia ea?oioaea Pseudomonas mallei
aeaao ?ino a aeaea eaiaeue iaaea

yiaeioienei

PAGE 12

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