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Хронический тубулоинтерстициальный нефрит

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O?iie/aneee ooaoeieioa?noeoeeaeueiue iao?eo.

Yoi — a?oiia, e eioi?ie ioiinyony ana aeaeu o?iie/aneeo caaieaaaiee
ii/ae. i?e eioi?uo aaia?aeeciaaiiua eee eieaeueiua eciaiaiey a
ooaoeieioa?noeoeeaeueiie iaeanoe i?aiaeaaeatho iaae aeiia?oey?iuie eee
ninoaeenouie ii?aaeaieyie. Ii i?e iiiaeo ii/a/iuo caaieaaaieyo iiieii
ae?oaeo no?oeoo?, ii?aaeaeythueo oa/aiea caaieaaaiey, a i?ioeann
aiaeaeaaony ooaoeieioa?noeoeeaeueiay iaeanoue, e, oaeei ia?acii,
auaeaeaiea a?oiiu ooaoeieioa?noeoeeaeueiuo caaieaaaiee yaeyaony a
aeinoaoi/iie ia?a oneiaiui. E?iia oiai, iaeioi?ua iauea eciaiaiey a
i?aaiecia (oaeea, eae naoa?iue aeeaaao) i?eaiaeyo e
ooaoeieioa?noeoeeaeueiiio ainiaeaieth.

Ii ?acee/iui aeaiiui io o?aoe aei iieiaeiu neo/aaa o?iie/aneie ii/a/iie
iaaeinoaoi/iinoe naycaiu n o?iie/aneei ooaoeieioa?noeoeeaeueiui
ainiaeaieai e ieiei 20% neo/aaa naycaii n o?iie/aneei oiio?aaeaieai
aiaeueaaoeeia.

Iaoaeiai-aiaoiie/aneay ea?oeia aeiaieueii oa?aeoa?ia, ianiio?y ia
?acee/iua i?e/eiu e ii?oieiae/aneea i?eciaee. Iae?ineiie/anee ii/ee
oiaiueoaiu a ?acia?a, ao?ioe/iu. I?e aicaeaenoaee oieneiia, ia?ooaieyo
iaoaaieecia, ianeaaenoaaiiuo aiiiaeeyo iaaethaeaaony neiiao?e/iia e
aeaonoi?iiiaa ii?aaeaiea; i?e ae?oaeo i?e/eiao aiciiaeii aneiiao?e/iia
?oaoeaaaiea ii/ee eee aiaea/aiea a i?ioeann oieueei iaeiie ii/ee.

I?e iano?oeoeaiie o?iiaoee e i?e aaeoa?eaeueiii ieaeiiao?eoa, a ioee/ea
io ae?oaeo caaieaaaiee, iaycaoaeueii ii?aaeathony ii/a/iua eioaiee.
Iaeiaei i?e iao?ioiene/aneeo ii?aaeaieyo, i?e na?iiaeaeii-eeaoi/iie
aiaiee, iano?oeoeaiuo o?iiaoeyo e naoa?iii aeeaaaoa aiciiaeii
iia?aaeaeaiea ii/a/iuo nini/eia e ?anoyaeaiea /aoa/ae n iineaaeothuei
?oaoeaaaieai ei?eiaiai aauanoaa iaae ieie. Eeoai/ee: iiaoo auoue ia
iia?aaeaeaiiuie, a iiaoo auoue iieiinoueth ?ac?ooaiu. Eaiaeueoeu
iiaeaa?aathony ao?ioee, i?inaao iiaeao auoue ?anoe?ai, a iai i?e
aenoieiae/aneii enneaaeiaaiee aiciiaeii iaia?oaeeoue aiiiaaiiua
oeeeeiae?u. Eioa?noeoeeaeueiay oeaiue eioeeueo?e?iaaia
iieeii?oii-yaea?iuie eaeeioeeoaie, oea?ice?iaaiia.

Eeeie/aneay ea?oeia.

*anoi o?iie/aneee ooaoeieioa?noeoeeaeueiue ieaeiiao?eo, iniaaiii ia
?aiieo yoaiao, i?ioaeaao aanneiioiiii, eeai neiioiiaoeea ia au?aaeaia.
Iiaoo iaaethaeaoueny neiioiiu eaiaeueoeaaie aeenooieoeee: iieeo?ey,
aeiiaieaiey aneaaenoaea iaaeinoaoi/iinoe ?aaani?aoeee iao?ey,
aeia?eaeeaiey e iaoaaiee/aneee aoeeaeic. Ia ?aiieo yoaiao ioaee
ieieiaeueiu, aiciiaeia iaaieueoay i?ioaeio?ey, aaiaoo?ey auaaao ?aaeei,
a?oa?eaeueiia aeaaeaiea iiaeao auoue iiauoaii, ii iaiaycaoaeueii.

I?e i?eniaaeeiaiee ianneaiie i?ioaeio?ee e aaiaoo?ee neaaeoao aeoiaoue
ia ineiaeieaoai oa/aiea eioa?noeoeeaeueiiai ieaeiiao?eoa
aeiia?oeiiao?eoa.

Anee o?iie/aneee ooaoeieioa?noeoeeaeueiue ieaeiiao?eo naycai n
ienaeaoo?eae, aeia?eaeueoeeaieae, na?eieaeicii, oi a ea/anoaa
ineiaeiaiee aiciiaeii ?acaeoea o?ieeoeaca.

A ea/anoaa naiinoiyoaeueiiai caaieaaaiey iiaeii auaeaeeoue
yiaeaie/aneoth aaeeaineoth iao?iiaoeth, caaieaaaiea iayniiai aaiaca,
aiciiaeii iaoneiaeaiiia aicaeaenoaeai ae?oniiai eee a?eaeiaiai oieneia.
Iee caaieaaaaiinoe i?eoiaeeony ia aeeaiacii iaaeaeo 30 e 60 aiaeaie.
ianeaaenoaaiiie i?aae?aniieiaeaiiinoe ia iaaethaeaaony. O oao, eoi
iieeaeaao yiaeaie/iua ?aeiiu a iieiaeii aic?anoa, aieaciue ia
?acaeaaaony.

Ia/aei ieeiaaea ia auaaao ino?ui. Caaieaaaiea iaia?oaeeaaaony i?e
i?iaaaeaiee iau/iuo enneaaeiaaiee: iaaethaeathony i?eciaee o?iie/aneie
ii/a/iie iaaeinoaoi/iinoe e i?ioaeio?ey. Niaoeeoe/aneea i?eciaee:
oyaeaeay aiaiey, iao ioaeia, ?aaeei ?acaeaaaony a?oa?eaeueiay
aeia?oaicey. Aeaoaeou neooa eee c?aiey ia oa?aeoa?iu aeey aeaiiiai
caaieaaaiey. Oa/aiea caaieaaaiey iaaeeaiii-i?ia?anne?othuaa e /a?ac
10-20 eao iinea ia?auo iauaeoeaiuo neiioiiia ?acaeaaaony oa?ieiaeueay
noaaeey ii/a/iie iaaeinoaoi/iinoe. O 30-40% aieueiuo iaia?oaeeaathony
ceiea/anoaaiiua iiaiia?aciaaiey.

O?iie/aneee aaeoa?eaeueiue ieaeiiao?eo (o?iie/aneee aaeoa?eaeueiue
ooaoeieioa?noeoeeaeueiue iao?eo).

O?iie/aneia, iaaiiiaaiiia, /anoi aeaonoi?iiiaa aiieiia eioaeoeeiiiia
ii?aaeaiea ii/ae, i?eaiaeyuaa e ao?ioee e aeaoi?iaoeee ii/a/iuo /aoa/ae
n ?oaoeaaaieai ?aniieiaeaiiie iaae ieie ia?aioeiie. A 2-3% neo/aaa
caaieaaaiea i?eaiaeeo e oa?ieiaeueiie noaaeee ii/a/iie iaaeinoaoi/iinoe
aeaeueiaeoaa ea/aiea i?iaiaeeony iooai o?iie/aneiai aaiiaeeaeeca eee
o?aiieaioaoeee ii/ee.

Ianiio?y ia o?iie/aneoth ii/a/ioth aaeoa?eo?eth, o?iie/aneee
aaeoa?eaeueiue ieaeiiao?eo ?aaeei i?eaiaeeo e i?ia?anne?othuae ii/a/iie
iaaeinoaoi/iinoe, ca eneeth/aieai neo/aaa, eiaaea ieaeiiao?eo ni/aoaaony
n iano?oeoeaiie o?iiaoeae.

Iaoieiai-aiaoiie/aneay ea?oeia o?iie/aneiai aaeoa?eaeueiiai ieaeiiao?eoa
ianiaoeeoe/ia e noiaeia n iaaethaeaaiie i?e ae?oaeo ii?aaeaieyo,
aucuaathueo ooaoeieioa?noeoeaeueioth iao?iiaoeth. Iaeaieaa niaoeeoe/iia
eciaiaiea — yoi ?oaoeaaaiea ia?aioeiu n ?ao?aeoeeae i?eeaaeaueo
nini/eia. Aa?iyoii. /oi eieoeee?othuei oaeoi?ii yaeyaony ia?ae/iia
ii?aaeaiea nini/eia aaeoa?eaeueiui eee eiui aaaioii. Yoi iia?aaeaeaiea
i?eaiaeeo e iineaaeothuae ooaoeieioa?noeoeeaeueiie ao?ioee, ?anoe?aieth
/aoa/ae e neea?ico eaaeauaai iaae ieie ei?eiaiai aauanoaa.

Eeeie/aneay ea?oeia.

Eeeie/aneea i?iyaeaiey ianiaoeeoe/iu. Yoi — aieue a iiynieoea eee a
aeeaioa, eeoi?aaeea. Iaee/ea a aiaiiaca eioaeoeee ii/aauo iooae eee
?aoeeaeeae?othuaai ino?iai ieaeiiao?eoa iiiiaaao iinoaiiaea aeeaaiica.

?aoeaaeeae?ouay eioaeoeey ii/aauo iooae e niaieoiiinoue oeie/iuo
i?eciaeia ii/a/iie aeenooieoeee oaaaeeoaeueii naeaeaoaeuenoaotho a
iieueco o?iie/aneiai aaeoa?eaeueiiai ieaeiiao?eoa. I?e yene?aoi?iie
o?ia?aoee iiaeii aeaeaoue ea?oeio, eioi?ay oaeaea iiaeao iaaethaeaoueny
i?e iocu?ii-ii/aoi/ieeiaii ?aoethena aac aaeoa?eo?ee e iiyoiio caeanue
o?aaoaony aeeooa?aioee?iaaoue yoe aeaa ninoiyiey. Anee iaeeoue a aaii/eo
ii/e e ano?yoiooue, aicieeoea iocu?e iiaeii ioianoe ia n/ao iaeie
?anoai?aiiinoe aieueo?aia.

I?e iano?oeoeaiie o?iiaoee — no?eeoo?ao ii/aoi/ieeia, o?ieeoeaca,
ieiiae?iaaiiuo ii?aaeaieyo, — e a neeo ?acee/iuo oaeoi?ia, i?eaiaeyueo
e ia?ooaieth o?iaeeiaieee iinaa ii/e iiaeao aeaoue iieiaeeoaeueiua
?acoeueoaou, ii iie ia iiaoo aeaoue aeinoiaa?iuo aeaiiuo i eieaeecaoeee
eioaeoeee.

I?ioaeio?ey ia ia/aeueiuo yoaiao ionoonoaoao, eeai auaaao ieieiaeueiie
aei oao ii?, iiea ia noi?ie?othony oea?iciua eciaiaiey a ii/eao. Ii e
oiaaea i?ioaeio?ey ?aaeei aeinoeaaao cia/eoaeueiuo aaee/ei (ioiioaiea
aaeie/e?aaoeiei iaiueoa aaeeieoeu). Ieieiaeueiay i?ioaeio?ey ia ?aiieo
noaaeeyo iiaeao auoue iaoneiaeaia ia ia?ooaieyie ooieoeee ii/ae, a
eaeeioeeo- e aaeoa?eo?eae.

Ii/aaie inaaeie neoaeiue, ii a iai iaia?oaeeaathony eeaoee ii/a/iiai
yieoaeey, ca?ienoua oeeeeiae?u e ec?aaeea eaeeioeeoa?iua oeeeeiae?u. I?e
ii?aaeaeaiee ooieoeeiiaeueiuo aiciiaeiinoae ii/ae iiaoo auoue auyaeaiu
ia?ooaiey eiioeaio?aoeeiiiie niiniaiinoe e aeia?oei?aie/aneee aoeeaeic
aua aei iiyaeaiey acioaiee.

Eeeie/aneia oa/aiea i/aiue ?aciiia?acii. A oeie/iuo neo/ayo aieaciue
i?ia?anne?oao i/aiue iaaeeaiii, i?e/ai ooieoeey ii/ae inoaaony
ii?iaeueiie a oa/aiea aeeeoaeueiiai a?aiaie — 20 eao e aieaa. I?iaiic
caaeneo io neaaeothueo oaeoi?ia: /anoioa ?aoeeaeeaia e oei iano?oeoeee
ii/aauaiaeyueo iooae. *ai auoa /anoioa ?aoeeaeeaia ino?iai ieaeiiao?eoa
eee iaino?aiee oa/aiey o?iie/aneiai ieaeiiao?eoa, e /ai neeueiaa
noaiaiue iano?oeoeee, oai iaaeaaii?eyoiaa i?iaiic. Iinoiyiiua ia?ooaiey
o?iaeeiaieee i?eaiaeyo e iiauoaieth aeaaeaiey a /aoa/ii-eioaii/iie
nenoaia e i?eaiaeyo e iia?aaeaeaieyi a ii/ea, e a oi aea a?aiy,
nicaeatho aeaaii?eyoiua oneiaey aeey aaeoa?eaeueiie eioaeoeee.

Ea/aiea.

Ea/aiea aeieaeii auoue iai?aaeaii iaeiia?aiaiii ia ono?aiaiea ia?ooaiee
o?iaeeiaieee e ia eeeaeaeaoeeth eioaeoeee. Iacia/aoue aioeaaeoa?eaeueiua
i?aia?aou iaeuecy i?e nio?aiythuaeny iano?oeoeee, oae eae
aaeeiia?aiaiiay aeaaeue aieueoiai eiee/anoaa aaeoa?ee i?e ia?ooaieyo
o?iaeeiaieee iiaeao i?eaanoe e aaeoa?eaeueii-oiene/aneiio oieo. Ea/aiea
ineiaeiaiee — aeia?oaicee, ii/a/iie iaaeinoaoi/iinoe — aeieaeii
i?iaiaeeoueny ii niioaaonoaothuei noaiai.

O?iie/aneay ii/a/iay iaaeinoaoi/iinoue.

O?iie/aneay ii/a/iay iaaeinoaoi/iinoue iiaeao auoue iaoneiaeaia
neaaeothueie i?e/eiaie:

1. Caaieaaaiey, i?e eioi?uo oiaiueoaaony eiee/anoai iao?iiia.

2. Eioa?noeoeeaeueiua caaieaaaiey ii/ae.

3. Caaieaaaiey, i?eaiaeyuea e ia?ooaieth o?iaeeiaieee:

a. Aiiiaeee ?acaeoey:

aeenoiiee

ia?ooaiey oiaea ii/aoi/ieea

ia?ooaiey acaeiiioiioaiey ii/aoi/ieea e ii/a/iuo ninoaeia

aiiiaeee ?acaeoey /aoa/ii-eioaii/iie nenoaiu

?aoethenu

ioic ii/ee

b. I?eia?aoaiiua caaieaaaiey:

ioic ii/ee aneaaenoaea auno?iai iiooaeaiey, eioaineaiie oece/aneie
iaa?ocee

no?eeoeo?u ii/aoi/ieeia

aeia?iea/anoaaiiay aeia?ieacey i?inoaou

o?ieeoeac

noaiic o?ao?u

4. Nenoaiiua caaieaaaiey

5. Ianeaaenoaaiiua oi?iu iaoieiaee:

neiae?ii Oaieiie

neiae?ii Aeueii?oa

neiae?ii Aoaeian/a?a

iaaeoey?ii-eenoiciay aieaciue ii/ae

aieaciue Oaieaei-Aaiioa

6. A?oa?eaeueiay aeia?oaicey

7. Na?aea/iay iaaeinoaoi/iinoue

A oa/aiea ii/a/iie iaaeinoaoi/iinoe iiaeii auaeaeeoue o?e oacu:

1. Nieaeaiea ooieoeeiiaeueiuo ?aca?aia ii/ae.

2. Aeaeiiiainaoeey — nianoaaiii ii/a/iay iaaeinoaoi/iinoue.

3. O?aiey.

Eeeie/aneay ea?oeia:

A ia/aea caaieaaaiey eeeie/aneea i?eciaee ionoonoaotho. Nieaeaiea
ooieoeeiiaeueiuo ?aca?aia ii/ae iiaeii ii?aaeaeeoue oieueei i?e
i?iaaaeaiee niaoeeaeueiuo enneaaeiaaiee.

Barry M.Brenner e J.Michael Lazarus auaeaeytho neaaeothuea ia?ooaiey
i?e ii/a/iie iaaeinoaoi/iinoe, a oii /enea. naycaiiua n aeeaeecii:

ia?ooaiea aaeaina aeeaeeinoe e yeaeo?ieeoia

ianoaaeeueiinoue iauaia aeeaeeinoe (

ia?ooaiea aaeaina eaeey (

ia?ooaiea aaeaina iao?ey (

iaoaaiee/aneee aoeeaeic (

ia?ooaiea aaeaina oinoi?a (

aeiieaeueoeeaiey (

Yiaeie?eiii-iaoaaiee/aneea ia?ooaiey:

ii/a/iay inoaiaeeo?ioey ( eee (

inoaiiaeyoeey Ae

aoi?e/iue aeia?ia?aoe?aic ( eee (

ia?ooaiea oiea?aioiinoe e oaeaaiaeai (

aeia?o?eeaiey ( eee (

aeia?o?eaeeoea?eaeaiey (

aaeeiai-eaei?eeiay iaaeinoaoi/iinoue ( eee (

ia?ooaiea ?inoa e ?acaeoey (

aanieiaeea e iieiaay aeenooieoeey (

aiaii?ay (

Ia?aii-iuoa/iua ia?ooaiey:

ooiieyaiinoue (

ia?ooaiey nia (

aieiaiay aieue ( eee (

nieaeaiea iuoeaiey (

niiiieaioiinoue, eaoa?ae/aneea ninoiyiey (

“oeiiathuee o?aii?” (

aeia?eeiacu (

ia?aoa?e/aneay iaa?iiaoey ( eee (

neiae?ii “aaniieieiuo iia” ( eee (

ia?acu ( eee (

ieieeiion, noaei?iaeiua i?eiaaeee ( eee (

eiia (

noaei?iae Ae

aeeaeeciue aeenyeaeeea?aoeeiiiue neiae?ii Ae

aeeaeeciia neaaioiea Ae

ieiiaoey ( eee Ae

Na?aea/ii-ninoaeenoua e eaai/iua ia?ooaiey:

a?oa?eaeueiay aeia?oaicey ( eee (

canoieiay na?aea/iay iaaeinoaoi/iinoue, ioae eaaeeo (

ia?eea?aeeo (

ea?aeeiieiiaoey ( eee (

o?aie/aneia eaaeia (

onei?aiiue aoa?ineea?ic ( eee Ae

aeiioaicey, a?eoiee Ae

Aea?iaoieiae/aneea ia?ooaiey:

aeaaeiinoue ( eee (

aeia?ieaiaioaoeey (, ( eee Ae

eiaeiue coae (

yeoeiicu ( eee (

o?aie/aneee iciia (

AEaeoaei/ii-eeoa/iua ia?ooaiey:

aii?aeney (

oioiioa e ?aioa (

o?aie/aneee caiao eci ?oa (

aano?iyioa?eo (

ycaa aeaeoaeea ( eee (

aeaeoaei/ii-eeoa/iia e?iaioa/aiea (,( eee Ae

aaiaoeo Ae

?ao?aeoa?iue anoeeo Ae

ia?eoiieo Ae

Aaiaoieiae/aneea e eiioiieiae/aneea ia?ooaiey:

ii?iioeeoa?iay. ii?iio?iiiay aiaiey (

eeioioeeoiiaiey (

aaii??aae/aneee aeeaoac ( eee Ae

nieaeaiea ?acenoaioiinoe e eioaeoeeiiiui caaieaaaieyi ( eee (

nieaiiiaaaeey, aaiaoi-eeaiaeueiue neiae?ii, aeia?nieaieci (

eaeeiiaiey Ae

nieaeaiea eiioeaio?aoeee eiiieaiaioa a e?iae Ae

( ia?ooaiey, eioi?ua i?eia?aoatho iaiueooth au?aaeaiiinoue i?e
i?iaaaeaiee iioeiaeueiiai aaiiaeeaeeca e naycaiiie n iei oa?aiee.

( noieeea ia?ooaiey, ia oiaiueoathueany i?e i?iaaaeaiee aaiiaeeaeeca;
iiaoo aeaaea i?ia?anne?iaaoue.

Ae ia?ooaiey, naycaiiua n aeeaeeciie oa?aieae.

I?e/eiu ?aceiai i?ia?anne?iaaiey o?iie/aneie ii/a/iie iaaeinoaoi/iinoe.

1. Oiaiueoaiea yooaeoeaiiai iauaia oee?eoee?othuae e?iae :

a). nieaeaiea iauaia oee?eoee?othuae e?iae

b). i?ia?anne?othuay na?aea/iay iaaeinoaoi/iinoue

2) Eciaiaiea a?oa?eaeueiiai aeaaeaiey:

a). a?oa?eaeueiay aeiioiiey

b). eao?iaaiiay a?oa?eaeueiay aeiioaicey

3. Eioaeoeeiiiua caaieaaaiey

4. Iano?oeoeey ii/aauaiaeyueo iooae

5. Aicaeaenoaea iao?ioiene/aneeo aauanoa:

aieiiaeeeiceaeu, iaeioi?ua ianoa?ieaeiua i?ioeaiainiaeeoaeueiua
n?aaenoaa etc.

6. O?iiaic ii/a/iuo aai

Ea/aiea o?iie/aneie ii/a/iie iaaeinoaoi/iinoe.

Eiina?aaoeaiia ea/aiea o?iie/aneie ii/a/iie iaaeinoaoi/iinoe.

1. Aeeaoa

Ia?aie/aiea aaeea a ?aoeeiia i?aiyonoaoao iaeiieaieth acioenouo oeaeia,
niiniaia caoi?iiceoue i?ia?anne?iaaiea ii/a/iie iaaeinoaoi/iinoe.

Anee nei?inoue eeoai/eiaie oeeueo?aoeee ieaea 30 ie. a ieiooo. oi
nooi/iia iio?aaeaiea neaaeoao nieceoue aei 0.6-0.7 a. ia eeeia?aii aana,
i?e/ai i?iaeoeou aeieaeiu iaeaaeaoue aunieie yia?aaoe/aneie
oeaiiinoueth: aaeaeaaoiay eaei?eeiinoue ieue iicaieyao nieceoue
eaoaaieeci aaeea. Ca aieueiui neaaeoao aieiaoaeueii iaaethaeaoue /oiau
ecaaaeaoue iaaeiaaeaiey.

Eiee/anoai eaeey a nooi/iii ieuaaii ?aoeeiia ia aeieaeii i?aauoaoue 40
iyea i?e nei?inoe eeoai/eiaie oeeueo?aoeee ieaea 20 ie. a ieiooo.

Oinoi? e eaeueoeee: auaaaeaiea oinoi?a oiaiueoaaony, /oi i?eaiaeeo e
aeia?oinoaoaiee e aeiieaeueoeeaiee. Oaiaoaiea neioaca yiaeiaaiiiai 1.25-
aeeaeae?ieneoieaeaeueoeeoa?iea e ?acenoaioiinoue einoiie oeaie e
ia?ao-ai?iiio onoaoaeytho aeiieaeueoeeaieth, /oi i?eaiaeeo e aoi?e/iiio
aeia?ia?aoe?aico. I?e ionoonoaee naiaa?aiaiiie ei??aeoeee yoi i?eaiaeeo
e ?acaeoeth ii/a/iie inoaiaeeno?ioee. oaaee/aiea niaea?aeaiey a e?iae
oinoaoiuo eiiia niinianoaoao i?ia?anne?iaaieth o?iie/aneie ii/a/iie
iaaeinoaoi/iinoe. Anee nei?inoue eeoai/eiaie oeeueo?aoeee ieaea 50 ie. a
ieiooo, oi niaea?aeaiea oinoi?a a nooi/iii ?aoeeiia ia aeieaeii
i?aauoaoue 800-1000 ia. I?e aeaeueiaeoai nieaeaiee nei?inoe eeoai/eiaie
oeeueo?aoeee ia?aie/aiea i?eaia oinoi?a ia noieue yooaeoeaii e oiaaea
iiaeii iacia/eoue i?aia?aou, naycuaathuea oinoi? e nieaeathuea aai
ananuaaiea a eeoa/ieea. Yoi — aioaoeeaeiua n?aaenoaa. niaea?aeauea
aeae?iieenue aethieiey e ea?aiiao eaeueoeey. Iaaeinoaoeii n?aaenoa,
niaea?aeaueo aethieiee yaeyaony iaeiieaiea aethieiey a oeaiyo, /oi
aucuaaao inoaiiaeyoeeth e, aiciiaeii, yioeaoaeiiaoeth. Ea?aiiao
eaeueoeey iaeuecy i?eiaiyoue, anee niaea?aeaiea oinoi?a a nuai?ioea
e?iae ieaea 7ia%. I?iecaaaeaiea eiioeaio?aoeee eaeueoeey e oinoi?a
ioaeii iiaeaea?aeeaaoue a i?aaeaeao 60. /oiau ecaaaeaoue yeoiie/aneie
eaeueoeeoeeaoeee. Aeey ai?ueau n aeiieaeueoeeaieae iacia/atho iaoaaieeou
aeoaieia D.

Ia?aie/aiea iio?aaeaiey iao?ey e aiaeu. Yoio aii?in yaeyaony nii?iui.
Iaeio?ua enneaaeiaaoaee ia yenia?eiaioao n aeaieiui neaiui eiio?ieai
iieacaee, /oi aannieaaay aeeaoa e?iia iiauo iaa?icia e ineoieia/aneiai
aeeneiioi?oa ie/aai ia aeaao. A oi a?aiy, eae ineoe/aneee aeeneiioi?o
iiaeao i?eaiaeeoue a aeinoaoi/ii aieueoii i?ioeaioa neo/aaa e
i?a?anne?iaaieth o?iie/aneie ii/a/iie iaaeinoaoi/iinoe.

I?e o?iie/aneie ii/a/iie iaaeinoaoi/iinoe iaaiee iaeaieeaaaony a
i?aaiecia. Iaiaoiaeeii ecaaaaoue ecauoi/iiai iinooieaiey iaaiey, a
oaeaea inoi?iaeii i?eiaiyoue i?aia?aou. oiaiueoathuea auaaaeaiea iaaiey.

2. A?oa?eaeueiay aeia?oaicey iiaeao onei?eoue oa/aiea o?iie/aneie
ii/a/iie iaaeinoaoi/iinoe. Aeeo?aoeee neaaeoao iacia/aoue iiae
ouaoaeueiui eiio?ieai, /oiau ecaaaeaoue aeiiaeae?oaoeee e aeiiaieaiee.
Iaoeaaua aeeo?aoeee inoathony yooaeoeaiuie i?e iaaeaiee nei?inoe
eeoai/eiaie oeeueo?aoeee ieaea 25 ie. a ieiooo.

3. Aoeeaeic ei??aae?otho iacia/aieai aeea?aiiaoa iao?ey, 300-600 ia.
aioo?ue 3 ?aca a nooee, anee niaea?aeaiea aeea?aiiaoa iao?ey a nuai?ioea
e?iae iaiueoa 16 iyea. Oaaee/aiea iinooieaiey iao?ey iiaeao iio?aaiaaoue
iacia/aiey aeeo?aoeeia.

4. Aiaiey yaeyaony iaeiie ec i?e/ei. iaoneaaeeaathuae neiioiiaoeeo
o?iie/aneie ii/a/iie iaaeinoaoi/iinoe. Iaoeeaioai iacia/atho
?aeiiaeiaioiue /aeiaa/aneee y?eo?iiiyoei. Ia/aeueiay aeica — 50 IA/ea
iiaeeiaeii 3 ?aca a iaaeaeth. Ai a?aiy eo?na iaiaoiaeeii iiieoi?e?iaaoue
a?oa?eaeueiia aeaaeaiea, iineieueeo iiaeao ?acaeoueny a?oa?eaeueiay
aeia?oaicey eae ineiaeiaiea i?eaia y?eo?iiiyoeia.

5. Ii/a/iay inoaiaeeno?ioey iaoneiaeaia aoi?e/iui aeia?ia?aoe?aicii,
iiieaeaiiui einoiui iaoaaieeciii eee ni/aoaieai yoeo i?e/ei.

E eeeie/aneei i?iyaeaieyi ioiinyony aiee a einoyo, ia?aeiiu, iuoa/iay
neaainoue, eiaeiue coae e eaeueoeeoeeaoeey iyaeeo oeaiae. O?iaaiue
ia?ao-ai?iiia, ii?aaeaeyaiue ?aaeeieioiiui iaoiaeii, cia/eoaeueii
iiauoai i?e oea?iciii innaeoa, e ia oae cia/eoaeueii. i?e ia?ooaieyo
einoiiai iaoaaieecia. ?aioaaiieiae/anee i?e oea?iciii innaeoa
ii?aaeaeyaony iiaeiaaeeinoie/iay ?aci?aoeey einoiie oeaie e
ia?aaiiia?iue inoaineea?ic.

Aeeaaiinoeea ii/a/iie inoaiaeeno?ioee iniiaaia ia ?yaea i?eciaeia.
Eeeie/anee iiaeii ia?aoeoue aieiaiea ia eiaeiue coae e eaeueoeeoeeaoeeth
ieieinonoaaiuo oeaiae. /oi aiai?eo i aeia?ia?aoe?aica. I?e iaeiieaiee
aethieiey a oeaiyo oa?aeoa?iu aeia?eaeueoeeaiey, ioiineoaeueiue
aeiiia?aoe?aic, eeeie/anee — “iaoieiae/aneea” ia?aeiiu.

Caaea/e ea/aiea: iiaeaea?aeaoue ia ii?iaeueiii o?iaia eiioeaio?aoeee
eaeueoeey e oinoi?a a e?iae e oeaiyo, iiaeaaeaiea aoi?e/iiai
aeia?ia?aoe?aica, i?aaeoi?aaeaeaiea yeoiie/aneie eaeueoeeoeeaoeee,
ia?aoiia ?acaeoea einoiuo eciaiaiee, i?aaeoi?aaeaeaiea e ei??aeoeey
oiene/aneiai aicaeaenoaey aeethieiey.

Eaeueoeeo?eie 0.25 – 1.0 iea aioo?ue 1 ?ac a aeaiue aeey iiaeaaeaiey
aeia?ia?aoe?ica.

Ia?aoe?aiyeoiiey ia?aaeei iaiaoiaeeia i?e oyaeaeii aeia?ia?aoe?aica.
Iieacaiey: au?aaeaiiay onoie/eaay aeia?eaeueoeeaiey, coae. ia
i?ae?auathueeny a oneiaeyo i?iaaaeaiey aeeaeeca e aaeaeaaoiie
iaaeeeaiaioiciie oa?aiee,i?ia?anne?othuay yeoiie/aneay eaeueoeeoeeaoeey,
neeueiua aiee a einoyo, “iaoieiae/aneea” ia?aeiiu, eoaie/aneea iae?icu
oeaiae, iaoneiaeaiiua eaeueoeeoeeaoeeae ninoaeia – eaeueoeeoeeeney.

Aeeaeec iieacai i?e oyaeaeie aeia?eaeeaiee, aoeeaeica, cia/oaeueiie
ia?a?ocea iauaiii. E /eneo ae?oaeo iieacaiee ioiinyony o?aie/aneee
ia?eea?aeeo.?acaeaathuayny yioeaoaeiiaoey, eee ia?ooaiey aeeaou.
niiniaiua aucaaoue caaea?aeeo aeeaeeinoe eee onoaoaeoue o?aieth.

Ineiaeiaiey aaiiaeeaeeca:

Ino?ia e?iaioa/aiea e eiaaoeiiaoey, neiae?ii ia?ooaiiie iniiey?iinoe,
ia?eea?aeeo, a?oa?eaeueiay aeiioiiey, eieaeeciaaiiay eee
aaia?aeeciaaiiay eioaeoeey, o?iiaic a?oa?ei-aaiiciiai ooioa, aeeaeeciay
aeaiaioeey.

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