OA?E?ANUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

Ianai Aiae??e Ieaen?eiae/

OAeE 616.611-002-08:611-018.51:576.8.094.7

AEE?IIEENEIOIEE NEEAAe E?I?Ae?A IAIA?AI A?EO?IOeEO?A OAI?EO IA O?II?*IEE
AEIIA?OEIIAO?EO A AeEIAI?Oe? E?EOAAIIss

14.01.02 – aioo??oi? oai?iae

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a – 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a ?inoeooo? oa?ai?? AII Oe?a?ie, i. Oa?e?a.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe

Oii/?e ?aai ?aaiiae/,

?inoeooo oa?ai?? AII Oe?a?ie, i. Oa?e?a,

caa?aeoaa/ a?aeae?eii iao?ieia??

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, aeioeaio

Aeanaiei Ieoaeei Aioiiiae/,

i. Oa?e?a, Oa?e?anueeee ?inoeooo oaeineiiaeaiiy e?ea??a

caa?aeoaa/ eaoaae?ith oa?ai?? oa iao?ieia??

aeieoi? iaaee/ieo iaoe, aeioeaio

Aaa??e Aiae??e Aaeoa?aeiae/,

i. Aeiiaoeuee, Aeiiaoeueeee aea?aeaaiee iaaee/iee

oi?aa?neoao, aeioeaio eaoaae?e

oa?ai?? oaeoeueoaoo i?neyaeeieiiiiai iaa/aiiy

I?ia?aeia i?aai?caoe?y: ?inoeooo o?ieia?? oa iao?ieia?? AII Oe?a?ie,

i. Ee?a, a?aeae?e oa?aiaaoe/ii? iao?ieia??

Caoeno aeena?oaoe?? a?aeaoaeaoueny “22” ea?oiy 1999 ?. i 1330 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.600.04 i?e Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca aae?anith: 310022, i. Oa?e?a,
i?. Eai?ia, 4.

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (310022, i. Oa?e?a, i?. Eai?ia, 4).

Aaoi?aoa?ao ?ic?neaiee “20” aa?aciy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
E.?. Ia/a?aiei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie.

Iaei??th c iaea?eueo iioe?aieo i?e/ei o?ii?/ii? ie?eiai? iaaeinoaoiino?
(OII) — ? o?ii?/iee aeiia?oeiiao?eo (OAI). Neeaaei?noue ?aiiuei?
ae?aaiinoeee oa iaia?aaeaa/aii?noue aoaeoeaiino? aeei?enoaiiy no/anieo
cania?a ? iaoiae?a e?eoaaiiy, ye? /anoi ii?aeiai? c ?eceeii ?icaeoeo
iia?/ieo yaeu oa oneeaaeiaiue, a oaeiae canoinoaaiiy iicaie?eiaeo
iaoiae?a aeaoieneeaoe?? i?e oa?i?iaeuei?e noaae?? OII – iaoiiaeth?
iaiao?aei?noue oaeineiiaeaiiy ?nioth/eo oa iiooeo iiaeo iaoiae?a
e?eoaaiiy OAI (?yaia N.?., 1996; Cameron J., 1992).

Ca inoaii? aeanyoe??//y cia/ii ?icoe?eeeny oyaeaiiy i?i iaoai?cie
?icaeoeo aeiia?oeiiao?eo?a. Oi/a a ?o iaoiaaiac?, ye caaaeaee aieiaia
cia/aiiy i?eae?ey?oueny ?ioiicaiaeueiei i?ioeanai, c’ynoaaeiny, ui a
iiaeaeueoiio i?ia?anoaaii? ?acii c ?ioiieie oaeoi?aie cia/io ?ieue
a?ae?a?athoue ia?ioii? iaoai?cie (Brenner B.M. et al., 1992; Hostetter
T.N. et al., 1995).

Ana a?eueoa iniaeeai? oaaae iaoeiaoe? i?eae?eythoue aea/aiith iiaeeea?e
o/ano? e?i?ae?a o ?icaeoeo ? i?ia?anoaaii? o?aaeaiiy ie?ie. C
e?i?aeiaaiiith ae??th ia oeaieio ie?ie o?nii iia’ycai? ? i?ioeane
a?eueii?aaeeeaeueiiai ieeneaiiy, ye? aeeth/athoue ? ia?aeenia ieeneaiiy
e?i?ae?a (IIE) (I?a??ia I.?. oa ?i., 1992; Clemens M.R. et al., 1989).
I?ioeane IIE aaniina?aaeiuei aieeaathoue ia i?ia?anoaaiiy iao?eo?a,
ae?th/e oeeoioiene/ii ia iacaia?aeuei? ee?oeie, ? noeioeththoue neioac
eieaaaio. A?eueoa oiai, IIE i?ecaiaeeoue aei aeanoaa?e?caoe?? ee?oeiieo
iaia?ai a ?acoeueoao? ie?neaiiy iaiane/aieo aee?ieo eeneio (IIAEE) o
neeaae? oinoie?i?ae?a (OE) (Ee?iia A.I. oa ?i., 1995; Chwiecko M. et
al., 1993).

Iaea?eueo c?o/iei ? aeinooiiei ia’?eoii aeine?aeaeaiiy noaio iaia?ai i?e
aeiia?oeiiao?eoao ? iaia?aia a?eo?ioeeoa, yea yaey? niaith oi?aa?naeueio
iiaeaeue ieaciaoe/ii? iaia?aie. AEe?i? eeneioe (AEE) – iaei?ino?o? ca
aoaeiaith e?i?aee, a i?aai?ci? neoaeaoue i?ii?aeiith eaieith i?e
?iciaae? aai neioac? ?ioeo e?i?ae?a. I?e oeueiio AEE yaeythoue niaith
iaea?eueo o?aceeao eaieo iaia?aiieo e?i?ae?a a iioean? caiaeaiiy, e??i
oiai, iie?iaiane/ai? aee?i? eeneioe (IIAEE) aenooiathoue iiia?aaeieeaie
aeeicaii?ae?a (eaeeio???i?a oa i?inoaaeaiaeei?a) (Eoioe A. oa ?i., 1994;
Bennet W.M. et al., 1989).

Ii?ooaiiy ?ioaa?aeueii? oe?e?niino? iaia?aie a?eo?ioeeo?a i?e o?ai?? –
iaeia c i?e/ei aeieeiaiiy aiai??, oaeiae iio?aao? aea/aiiy
aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai a?eo?ioeeo?a aeey ?icoi?iiy
iaoiaaiaco aaiie?co i?e o?ii?/i?e ie?eia?e iaaeinoaoiino? (OII).
Iac’yniaaieie caeeoathoueny ieoaiiy aieeao ia noai iaia?aie a?eo?ioeeo?a
iaia?aiinoaa?e?coth/i?, aio?aiai?/ii?, aeacaa?aaaoe?eii?, a?iioaiceaii?
oa aoa?aioii? oa?ai?e i?e OAI c ??cieie noaae?yie OII (Ie??a E.A. oa
?i., 1994; Koch K.M. et al., 1997).

O ca’yceo c oeei, aeooaeuei?noue aeena?oaoe?eiiai aeine?aeaeaiiy
iaoiiaeaia iaiao?aei?noth iioei?caoe?? oa?ai?? OAI, a oiio /ene?
iiaeeea?noth aeeth/aiiy iaia?aiinoaa?e?coth/i? oa?ai?? c iaoith
i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy, a oaeiae caaania/aiith aaeueioaaiiy
i?ioeano iioeiaeaeaiiy ee?oei. Ia?niaeoeaiei iai?yieii a ee?i?/i?e
iao?ieia?? ? oaeiae canoinoaaiiy i?aia?ao?a, ye? aeicaieyoue oni?oii
aieeaaoe ia iniiai? eaiee iaoiaaiaco ie?eiai? iaaeinoaoiino? (aiai?y,
o?ai?y).

Oaeei /eiii, iaaaeyea cia/aiiy iaaoaa? aea/aiiy ci?i aee?iieeneioiiai
neeaaeo e?i?ae?a iaia?ai a?eo?ioeeo?a, yea aeicaieeoue ?ic?iaeoe iia?
iaoiaee ei?aeoe?? aeyaeaieo ii?ooaiue, ioe?ieoe aoaeoeai?noue oa?ai??,
oa ciaioeoe i?e oeueiio iiaeeea?noue aeieeiaiiy iaaaaeaieo iia?/ieo
aoaeo?a iaaeeeaiaioicii? oa?ai?? ? oei naiei ni?eyoeia oaeineiiaeaiith
e?eoaaiiy OAI.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie.

Aea?aiee iai?yiie aeine?aeaeaiue ca’ycaiee c iaoeiaith ae?yeuei?noth oa
aoiaeeoue aei oaiaoe/iiai ieaio ?inoeoooa oa?ai?? AII Oe?a?ie, ye
o?aaiaio IAe?: “?ic?iaea iaoiae?a e?eoaaiiy OAI c o?aooaaiiyi
iaia?aiioeeoiieaciaoe/ieo aca?iia?aeiioaiue ?ioiieiiiaoaioieo ee?oei
e?ia? oa c canoinoaaiiyi iaoiae?a aoa?aioii? oa?ai??” – ?aa. ?
0194V0035070.

Iaoa ? caaea/? aeine?aeaeaiiy.

Iaoith ?iaioe noaei i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy o?ii?/iiai
aeiia?oeiiao?eoo ia i?aenoaa? ioe?iee noaio aee?iieeneioiiai neeaaeo
e?i?ae?a iaia?ai a?eo?ioeeo?a o oai?eo ia o?ii?/iee aeiia?oeiiao?eo c
o?aooaaiiyi aeoeaiino? i?ioeano oa noaae?? o?ii?/ii? ie?eiai?
iaaeinoaoiino?.

Aeey aeinyaiaiiy iaoe aoee iinoaaeai? ianooii? caaea/?:

-aea/aiiy aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai oa aa?aaaoe?eieo
aeanoeainoae a?eo?ioeeo?a o oai?eo ia OAI;

-aeine?aeaeaiiy a?io?ce/ieo aeanoeainoae a?ee?a iaia?ai a?eo?ioeeo?a oa
?o ci?i i?e OAI;

-aecia/aiiy aoaeoeaiino? iaia?aiinoaa?e?coth/i? oa?ai?? o oai?eo ia OAI
c ??cieie noaae?yie OII;

-aieea aio?aiai?/ii? oa?ai?? ia a?eo?ioeeoa?iee aaiinoac o oai?eo ia
OAI, ye? ciaoiaeyoueny ia i?ia?aiiiio aaiiae?ae?c?.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a.

Aia?oa ia i?aenoaa? eiiieaeniiai aeine?aeaeaiiy aee?iieeneioiiai neeaaeo
e?i?ae?a iaia?ai oa aa?aaaoe?eieo aeanoeainoae a?eo?ioeeo?a a aaiethoe??
OAI iieacaia aaaeeeaa ?ieue no?oeoo?ieo ci?i aee?iieeneioiiai neeaaeo
a?eo?ioeeoa?ieo iaia?ai ? iaia?aiii? iaoieia??.

Anoaiiaeai? iniaeeaino? ci?i aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai
a?eo?ioeeo?a a caeaaeiino? a?ae i?ia?anoaaiiy caoai?thaaiiy oa noao?
oai?eo, ui iia’ycaii c ??ciith ?ioaineai?noth ia?aeeniiai ieeneaiiy
e?i?ae?a ? iaiaeiaeiaei ??aiai ai?noo noaoaaeo ai?iii?a, ui aieeaa? ia
iaoaaie?/i? i?ioeane a oe?eiio.

Iieacaii ca’ycie i?ae iie?auaiiyi noaio aee?iieeneioiiai neeaaeo
e?i?ae?a iaia?ai a?eo?ioeeo?a oa iieacieeaie a?eo?ioeeoa?iiai aaiinoaco,
a oaeiae caaaeueieie ee?i?/ieie iieacieeaie.

Aia?oa aeey aeine?aeaeaiiy oaieio?ce/ieo ia?aiao??a ?ioaa?aeueieo oa
ia?eoa?e/ieo a?ee?a ee?oeiieo iaia?ai i?e OAI canoiniaai iaoiae
aeeoa?aioe?aeueii-neai??oth/i? eaei?eiao??? (AeNE).

Ca aeiiiiiaith nenoaiiiai aiae?co aea/aia niaoeeo?ea no?oeoo?ii?
ia?aaoaeiae ooieoe?iiaeueieo nenoai i?aai?cio oai?eo ia OAI i?e
e?eoaaii? iaia?aiinoaa?e?coth/eie i?aia?aoaie.

Iaa?oioiaaii ni?eyoeeaee aieea ia a?eo?ioeeoa?iee aaiinoac aioeaiai?/ii?
oa?ai?? a ii?aeiaii? c aaiiae?ae?cii o oai?eo ia OAI c oa?i?iaeueiith
noaae??th o?ii?/ii? ie?eiai? iaaeinoaoiino?.

Ca ?acoeueoaoaie i?iaaaeaieo iaoeiaeo aeine?aeaeaiue aeyaeaii
ioi?iiicaeaoia ??oaiiy: “Niin?a aeeoa?aioe?aeueii? ae?aaiinoeee
neiioiiaoe/ii? ?aiiia?aio?iaoicii? oa anaioe?aeueii? a?ia?oii?e”
(ni?aaao. A.N.Eiiueeiaa) – ?a?no?aoe?eiee iiia? cayaee: 97062749, aeaoa
iiaeaiiy 10.06.97; i?eeiyooy ??oaiiy 13.04.98.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

A ?acoeueoao? i?iaaaeaiiiai aeine?aeaeaiiy iieacaia aaaeeeaa ?ieue
aea/aiiy ci?i aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai a?eo?ioeeo?a
oai?eo ia OAI, ui aeicaiey? i?aeaeueoe ye?noue ?aiiuei? ae?aaiinoeee
oneeaaeiaiue, aeeeeea?ieo oe??th iaoieia??th (OII, aiai?y, n?iioiiaoe/ia
a?oa??aeueia a?ia?oaic?y).

Eiia?iiaaia oa?ai?y oai?eo OAI c canoinoaaiiyi iaia?aiinoaa?e?coth/iai
i?aia?aoo “Anaioe?aea” ai?iaaaeaeaia a i?aeoe/io ?iaioo ee?i?ee
?inoeoooo oa?ai?? AII Oe?a?ie, Oa?e?anueei? iaeanii? ee?i?/ii? e?ea?i?,
*oao?anueei? oeaio?aeueii? ?aeiiii? e?ea?i?, ui aeicaieeei cieceoe
/anoioo ?aoeeaeea?a caoai?thaaiiy OAI oa oieeiooe oneeaaeiaiue.
Canoinoaaiiy i?aia?aoo “Aaeeai?i” o oai?eo OAI c OII, ye? ciaoiaeyoueny
ia i?ia?aiiiio aaiiae?ae?c? ai?iaaaeaeaii a i?aeoe/io ?iaioo
a?aeae?eaiiy o?ii?/iiai aaiiae?ae?co Oa?e?anueei? iaeanii? ee?i?/ii?
e?ea?i?, ui aeicaieeei iie?ioeoe iieacieee a?eo?ioeeoa?iiai aaiinoaco.
Iioae?eiaaii ? ai?iaaaeaeaii iaoiaee/i? ?aeiiaiaeaoe??: “Canoinoaaiiy
iaoiae?a ieaciaoa?aco a e?eoaaii? oai?eo ia aeiia?oeiiao?eo” (ni?aao.
Ie??a E.A., Oii/?e ?.?., Aaee/ei I.A., O?oiaa O.A., Eica? A.A.).

Iniaenoee aianie caeiaoaa/a.

Ca ia??iae aeeiiaiiy aeena?oaoe?? aaoi? i?aoethaaa o a?aeae?e?
iao?ieia??, i?iaiaeea ?ioaineaio iaoeiao oa e?eoaaeueio ?iaioo a oeueiio
i?ae?icae?e? ?inoeoooo oa?ai??. Cae?enithaaa a?aea?? oaiaoe/ieo oai?eo
OAI aeey ianooiiiai ianoaaeaiiy oa iaaeeeaiaioiciiai e?eoaaiiy ?o a
oiiaao niaoe?ae?ciaaiiiai iao?ieia?/iiai a?aeae?eaiiy ?inoeoooo oa?ai??
AII Oe?a?ie. O a?aeae?e? caaania/oaaa anaa?/ia ianoaaeaiiy oai?eo,
cae?enithaaa eiio?ieue ca aoaeoeai?noth i?ioeano e?eoaaiiy, a oaeiae
aeeiai?/ia niinoa?aaeaiiy ca noaiii ?o caei?ia’y. Naiino?eii
canoiniaoaaa oae? iaoiaee aeine?aeaeaiiy oai?eo: aacio?iiaoia?ao?/iee
aiae?c AEE e?i?ae?a iaia?ai a?eo?ioeeo?a, oioiaeaeo?ieiei??iao?e/iee
iaoiae ?iaeooee?iaaii? aa?aaaoe?? a?eo?ioeeo?a, iaoiae
aeeoa?aioe?aeueii-neai??oth/i? eaei?eiao??? iaia?ai a?eo?ioeeo?a. Aaoi?
i?iaiae?coaaa ? ocaaaeueiea ?acoeueoaoe aeine?aeaeaiue, i?iaiaeea aiae?c
oa iaoaiaoe/io ia?iaeo io?eiaieo ?acoeueoao?a c aeei?enoaiiyi
aeaeo?iiii-ia/enethaaeueii? oaoi?ee, ioi?iethaaa aeena?oaoe?eio ?iaioo.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??.

Iaoa??aee aeena?oaoe?? aeiiia?aeaeenue ? iaaiai?thaaeenue ia
iaoeiai-i?aeoe/ieo eiioa?aioe?yo ?inoeoooo oa?ai?? AII Oe?a?ie
(1996-1998), ?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? iieiaeeo
a/aieo oa oao?aoe?a “No/ani? ooiaeaiaioaeuei? oa i?eeeaaei? i?iaeaie a
ee?i?oe? aioo??oi?o caoai?thaaiiyo” (Oa?e?a, 1997), ?anioae?eainuee?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? “?ieue caaaeueiii?aeoeeoth/iai e?ea?y o
?ica’ycaii? i?iaeai i?io?eaeoeee ia?ioaeoe?eieo caoai?thaaiue” (Oa?e?a,
1997), ia XIV c’?cae? oa?aiaao?a Oe?a?ie (Ee?a, 1998).

Ioae?eaoe??.

Ii oai? aeena?oaoe?? iioae?eiaaii 9 ae?oeiaaieo ?ia?o. Iioae?eiaaii 4 –
noaoo? a aeo?iaeao, 2 – a ca??ieeo iaoeiaeo i?aoeue. Iaae?oeiaaii oac
aeiiia?aeae – 3.

Ianya oa no?oeoo?a aeena?oaoe??.

Aeena?oaoe?eia ?iaioa aeeeaaeaia ia 160 noi??ieao iaoeiiieniiai oaenoo e
neeaaea?oueny ?c anooio, 2 aeaa iaeyaeo e?oa?aoo?e, 7 aeaa aeanieo
aeine?aeaeaiue, i?aenoie?a, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e. Nienie
aeei?enoaieo aeaea?ae i?noeoue 304 aeaea?aea, c ieo 77 aeaea?ae ia
oe?a?inuee?e oa ?in?enuee?e iiaao oa 227 ca?oa?aeieo aeaea?ae. ?iaioa
?ethno?iaaia 14 iaethieaie (ianyaii 9 noi??iie) oa 17 oaaeeoeyie
(ianyaii 13 noi??iie).

CI?NO ?IAIOE

Iaoa??aee ? iaoiaee.

Ia’?eoii aeine?aeaeaiiy aoee 106 in?a: 88 oai?eo ia OAI oa 18 /ieia?e –
eiio?ieueia a?oia (i?aeoe/ii caei?ia? iniae), ye? ciaoiaeeeenue ia
aeine?aeaeaii? oa e?eoaaii? a ee?i?oe? ?inoeoooo oa?ai?? AII Oe?a?ie.
Na?aae oai?eo aoei 49 (55,7 %) in?a /ieia?/i? noao? ? 39 (44,3 %) –
ae?ii/i? noao?. Na?aaei?e a?e ianoaaeaieo neeaa (43,3+3,7) ?iee.

Ae?aaiic OAI anoaiiaethaaany ia iniia? nea?a oai?iai, aiaiiaco, aeaieo
ia’?eoeaiiai ianoaaeaiiy, eaai?aoi?ieo oa ?ino?oiaioaeueieo iaoiae?a
aeine?aeaeaiiy. Ee?i?/io oi?io OAI anoaiiaethaaee ca eeaneo?eaoe??th
?.?.Oa?a?ai? (1995); noaae?y OII — ca eeaneo?eaoe??th I.ss.?aoia?a ?
ni?aaao. (1980). Ca?aeii oeei eeaneo?eaoe?yi oai?? aoee ?iciiae?eai? ia
3 iniiai? a?oie: 1 a?oia – oai?? ia OAI aac OII, 32 iniae (36,4 %); 2
a?oia – oai?? ia OAI c OII I-II noaae??, 26 in?a (29,6 %); 3 a?oia –
oai?? ia OAI c OII+OAAe, 30 in?a (34 %).

An?i oai?ei ianoaaeaiiy i?iaiaeeee ca noaiith, yea aeeth/aea
caaaeueiii?eeiyo? ee?i?ei-eaai?aoi?i? aeine?aeaeaiiy. Aaiiaeeiai?/i?
ia?aiao?e ioe?ithaaee iaoiaeii aoiea?ae?ia?ao?? ia aia?ao? “Aloka”
SSD-280 (ssiii?y) ca caaaeueiii?eeiyoith iaoiaeeeith (I.I.Iooa?eyiia,
1987; Miach P.J., 1981). Aecia/aeeny ianooii? iieacieee: e?ioeaaee
ae?anoie?/iee ?ici?? (EAe?), e?ioeaaee ae?anoie?/iee ia’?i (EAeI),
e?ioeaaee nenoie?/iee ?ici?? (EN?), e?ioeaaee nenoie?/iee ia’?i (ENI),
oiaueia caaeiuei? no?iee e?aiai oeoii/ea (OCNeo), oiaueia
i?aeoeoii/eiai? ia?aai?iaeee (OIOI), nooi?iue oei?i/aiiy
ia?aaeiuei-caaeiueiai ?ici??o e?aiai oeoii/ea (NO), o?aeoe?y aeeeaeo
(OA), iana i?iea?aeo e?aiai oeoii/ea (IIeo); ?ici??e ie?ie, oiaueia oa?o
ia?aio?ie ia ??ai? na?aaeiueiai naaiaioo, ?aiaeueii-ei?oeeaeueiee
?iaeaen (?E?), ?aiaeueiee eiao?oe??io (?E), i?e iayaiinoe eiie?aiaio?a
oa e?no anoaiiaethaaany ?o ?ici??.

Aeiaeaoeiai cae?enithaaeenue ne?aeoth/e iaoiaeeee: aacio?iiaoia?ao?/iee
aiae?c AEE e?i?ae?a iaia?ai a?eo?ioeeo?a; aecia/aiiy ?iaeooee?iaaii?
aa?aaaoe?? a?eo?ioeeo?a oioiaeaeo?ieiei?eiao?e/iei iaoiaeii;
aeeoa?aioe?aeueii-neai??oth/a eaei??iao??y ?cieueiaaieo iaia?ai
a?eo?ioeeo?a.

An? ?acoeueoaoe aeine?aeaeaiiy aoee ia?iaeai? ca aeiiiiiaith
noaiaea?oieo iaeao?a i?ia?ai Excel, Equation, Graph ia ia?niiaeueiiio
eiii’thoa?? c ia/eneaiiyi na?aaeiuei? aaee/eie I,
na?aaeiueieaaae?aoe/iiai a?aeoeeaiiy , na?aaeiuei? iiieeee na?aaeiuei?
aaee/eie m, e?eoa??th a??ia?aeiino? t, cia/aiiy a??ia?aeiino? ?.
A?aei?iiino? i?ae iieacieeaie, ui ii??aiththoueny c?ciaaaeenue
a??ia?aeieie, yeui cia/aiiy ?iia??iino? aoei a?eueo 95 % (p<0,05). E??i ia?aiao?e/ieo iaoiae?a noaoenoe/iiai aiae?co aeei?enoiaoaaeenue oaeiae iaia?aiao?e/i? iaoiaee – e?eoa??e ciae?a ? e?eoa??e A?eeieniia. Nenoaiiee aiae?c noeoiiino? iciae, ui aea/aeeny, i?iaiaeeany iaoiaeii ei?aeyoe?eieo no?oeoo? (A.I.Cin?iia, 1993). ?acoeueoaoe aeine?aeaeaiue. A ?acoeueoao? i?iaaaeaiiiai aeine?aeaeaiiy anoaiiaeaii, ui ii i??? i?ia?anoaaiiy OII o oai?eo ia OAI aecia/a?oueny a?oa??aeueia a?ia?oaic?y, c?inoa? o?ai?y oa aiai?y. O oai?eo 2 a?oie i?ae ??aiai e?aaoei?io a ne?iaaooe? e?ia? oa e?euee?noth a?eo?ioeeo?a anoaiiaeaii cai?ioi?e ei?aeyoe?eiee ca’ycie (r=-0,32; ?<0,05), o oai?eo, ye? ia?aaoaathoue ia aaiiae?ae?c? a?aeaoaa?oueny iineeaiiy ei?aeyoe?eiiai ca’yceo i?ae aeaieie iieacieeaie (r=-0,38; ?<0,05). Ia?aeaeueii ca?eueoaiith aiai?? ci?ith?oueny aaiiaeeiai?/iee i?io?eue e?iaiia?ao. Ci?ie aaiiaeeiai?ee a?aeiinii eiio?ieth iaea?eueo ae?aaeai? o oai?eo 3 a?oie. I?aeoaa?aeaeaiiyi oa?i?iaeueii? noaae?? OII o oai?eo 3 a?oie neoaeeoue aeinoia??ia (?<0,001) ca?eueoaiiy ?E? oa ?e a?aeiinii eiio?ieth, a oaeiae anoaiiaeaiee i?yiee ei?aeyoe?eiee ca’ycie i?ae ?E? oa ?e (r=+0,80; ?<0,001). I?e aiae?c? neeaaeo AEE e?i?ae?a iaia?ai a?eo?ioeeo?a o /ieia?e?a, ye ? o ae?iie o an?o o?ueio a?oiao a?aei?/a?oueny ciaioaiiy i?ioeaioiiai ai?noo IIAEE, a oie /an ye i?ioeaioiee ai?no IAEE c?inoa?. Iniaeeai yne?aai aeai? ci?ie a AEE neeaae? e?i?ae?a iaia?ai a?eo?ioeeo?a ae?aaeai? o oai?eo c oa?i?iaeueiith noaae??th OII. I?i c?inoaiiy aeyaeaieo ci?i c o?ii?caoe??th iaoieia?? na?ae/eoue oa, ui i?e OAI aac OII o /ieia?e?a aeyaeaia eeoa oaiaeaioe?y aei c?inoaiiy o ii??aiyii? c eiio?ieai ?iaeaena iane/aiino? (?i) (+17,48 %; ?>0,05) oa iieacieea N
20:4/N 18:2 (+4,19 %; ?>0,05); i?e OAI c OII I-II noaae?? a?aei?/a?oueny
aeinoia??ia c?inoaiiy ?i (+28,16 %; ?<0,05) oa oaiaeaioe?y aei c?inoaiiy iieacieea N 20:4/N 18:2 (+6,29 %; ?>0,05); a o oai?eo ia OAI c OII+OAAe
aeyaeaii aeinoia??ia ca?eueoaiiy ?i (+33,01 %; ?<0,05), ui na?ae/eoue i?i ?ioaineaio oo?e?caoe?th IIAEE a ?acoeueoao? aeoea?caoe?? IIE ? neioaco a?ieia?/ii aeoeaieo ?a/iaei, a oaeiae i?i iani?iiiaei?noue i?aai?cio oai?iai eiiiainoaaoe ao?aoe IIAEE i?e i?ia?anoaaii? caoai?thaaiiy. I?ioa ?i o ae?iie 1 oa 2 a?oi iaioa a ii??aiyii? c ?i o /ieia?e?a a?aeiia?aeieo a?oi (ia 1,65 % oa 3,79 %), ui aeaco? ia noaoaaee aeeii?o?ci. A 3 a?oi? ??cieoey i?ae ?i o /ieia?e?a ? ae?iie iacia/ia (ia 1,45 %), ui coiiaeaii ii?ooaiiyi ?ai?iaeoeoeaii? ooieoe?? o ae?iie, ye? ia?aaoaathoue ia i?ia?aiiiio aaiiae?ae?c?. Aeyaeai? ci?ie aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai a?eo?ioeeo?a i?ecaiaeyoue aei ii?ooaiue ia o?euee? o?i?/iiai neeaaeo a?eo?ioeeoa?ieo iaia?ai, aea e aei ci?i ?o ooieoe?iiaeueieo aeanoeainoae, cie?aia aa?aaaoe?eieo. Iaeneiaeueia oaeaee?noue ?iaeooee?iaaii? aa?aaaoe?? a?eo?ioeeo?a aeyaeaia o oai?eo ia OAI c OII+OAAe, iaeiaioa – i?e OAI aac OII, ui na?ae/eoue i?i cia/ia iia??oaiiy i?e?ioee?eoeyoe?? c i?ia?anoaaiiyi caoai?thaaiiy. Oe? iaaaoeai? ci?ie ?aieia?/ieo aeanoeainoae e?ia? aenooiathoue aeiaeaoeiaei iaoiaaiaoe/iei oaeoi?ii, yeee oneeaaeith? oa/?th caoai?thaaiiy ? ni?ey? o?ii?caoe?? i?ioeano. ?aiaee?oaaiiy aaaeo/eo cia/ou?o (t-e?eoa??e) iieaciee?a AEE an?o o?ueio a?oi aeyaeei iaea?eueoo iaoiaaiaoe/io aaaeeea?noue (t>2) na?aae IIAEE
anaioe?aeueieo AEE – e?iieaai?, e?iieaiiai?, aeeicao?e?iiai? oa
a?ao?aeiiiai?, ui iia’ycaii c i?enei?aiiyi ?o iaoaaie?cio ye
oeeeeiieneaaiaciei, oae ? e?iieneaaiaciei oeyoaie. I?e aiae?c?
nenoaiiooai?thth/eo aeanoeainoae ia?aiao??a ei?aeyoe?eieo no?oeoo? o
oai?eo ia OAI aoea anoaiiaeaia ne?aeoth/a ???a?o?y (?en.1).

OAI, OII 0 no. OAI, OII I-II no. OAI,
OII+OAAe

?en.1 ???a?o?y nenoaiiooai?thth/eo aeanoeainoae ia?aiao??a ei?aeyoe?eieo
no?oeoo? o oai?eo ia OAI

Aenieee ?aiaiaee nooi?iue iieaciee?a acioai?? o oai?eo 2 oa 3 a?oi
i?aeoaa?aeaeo? aaaeo/o iaoiaaiaoe/io ?ieue acioai?? i?e OAI c OII, a
noaa?eueia aeniea ?aiaiaa iiceoe?y iieaciee?a IIAEE o an?o o?ueio a?oiao
na?ae/eoue i?i i??i?eoaoio o/anoue a eiiiainaoi?ieo i?ioeanao nenoaie
AEE e?i?ae?a iaia?ai ee?oei.

Aeey aea/aiiy a?eie – e?i?aeieo aca?iia?aeiioaiue oa noaio aaiiaeia?io
aeei?enoiaoaaee iaoiae AeNE. Aoee io?eiai? a?aecia/i? i?ae niaith
eaei?eiao?e/i? i?io?e? oaiia?aoo?ieo ia?aoiae?a.

Iaea?eueoei ci?iai noeeuei? ?ioaa?aeuei? a?eee ia?aoiae?a A ? N, ye?
iiaeeaeai? a e?i?aeiee a?neie, ui i?aeoaa?aeaeo? iayai?noue ci?i a
no?oeoo?? e?i?ae?a. Ia?aoiaee A ? D (no?oeoo?ieo a?ee?a) – i?aeoe/ii ia
ci?iai? (?en.2). A?aei?/aii cieaeaiiy oaieiaiai aoaeoo aeaiaoo?aoe??
iieaeoee aaiiaeiaeio, ui na?ae/eoue i?i ii?ooaiiy i?inoi?iai? no?oeoo?e
iieaeoee aaiiaeia?io o oai?eo ia OAI. Aeacai? ia?aaoaeiae no?oeoo?iiai
noaio iieaeoee aaiiaeia?ia aenooiathoue ye aeieac ci?i oiia
ooieoe?iioaaiiy oeueiai a?eea, ui iia’ycaii c ii?ooaiiyi i?iieeeeainoe
ee?o?iii? iaia?aie aiane?aeie ci?i o aee?iieeneioiiio neeaae? e?i?ae?a
iaia?ai a?eo?ioeeo?a.

’’

’’

1 — OAI aac OII; 2 — OAI, OII I-II no.; 3 — OAI, OII+OAAe;

4 — eiio?ieue.

?en.2. Eaei?eiao?e/i? i?io?e? oaiia?aoo?ieo ia?aoiae?a iaia?ai
a?eo?ioeeo?a

Ine?eueee niaoe?o?/ieo iaoiae?a oa?ai?? OAI ia ?nio?, oa aeiaeai c
iaoiae?a oa cania?a, ye? canoiniaothoueny ia aea? aa?aio?? iiaiiai
iaeoaeoaaiiy – iniiaiith iaoith i?e e?eoaaii? OAI ? cieaeaiiy oaii?a
i?ia?anoaaiiy oa ia?aaeaa/aiiy ?icaeoeo OII. Oai?? 1 ? 2 ee?i?/ieo a?oi
io?eioaaee a?iioaiceai? caniae ? aeacaa?aaaioe. sse
iaia?ainoaa?e?coth/ee e?ea?nueeee can?a aeei?enoiaoaaee i?aia?ao
“Anaioe?aea” o neeaae? yeiai ? e?iieaaa oa e?iieaiiaa eeneioe, ca
noaiith: 5 ie aioo??oiueiaaiii i?ioyaii a?ae 5 aei 10 ae?a c iiaeaeueoei
i?eeiiii aioo??oiuei ii 2 eainoee o?e/? ia aeiao i?ioyaii a?ae 16 aei 20
ae?a.

I?ney i?iaaaeaiiai eo?no e?eoaaiiy ia oii? iie?ioaiiy caaaeueiiai noaio
oai?eo ? ee?i?/ieo iieaciee?a, a?aei?/aeinue ca?eueoaiiy i?ioeaioiiai
ai?noo IIAEE ye o /ieia?e?a, oae ? o ae?iie. Oaiaeaioe?y e ciaioaiith ?i
ii a?aeiioaiith aei iieaciee?a aei e?eoaaiiy ia 12,4 % (p>0,05) oa
iieacieea N 20:4/N 18:2 ia 3,4 % (p>0,05) o oai?eo 1 a?oie (/ieia?ee);
aeinoia??ia cieaeaiiy ?i ia 19,7 % (p<0,05) oa oaiaeaioe?y e cieaeaiith iieacieea N 20:4/N 18:2 ia 3,3 % (p>0,05) o oai?eo 2 a?oie (/ieia?ee) –
i?aeoaa?aeaeo? iiceoeai? ci?ie a aee?iieeneioiiio noai? e?i?ae?a iaia?ai
a?eo?ioeeo?a i?ae aieeaii iaia?aiinoaa?e?coth/i? oa?ai??. A iaio a?oiao
oai?eo ia OAI (ae?iee) a?aei?/a?oueny aeinoia??ia ciaioaiiy ?i: a 1
a?oi? – ia 15,9 % (p<0,05) oa a 2 a?oi? – ia 18,9 % (p<0,05), a oaeiae oaiaeaioe?y aei cieaeaiiy iieacieea N 20:4/N 18:2 – ia 0,69 % (p>0,05) a
1 a?oi? oa ia 6,12 % (p>0,05) – a 2 a?oi?.

Ia iiceoeaio aeeiai?eo no?oeoo?ii-ooieoe?iiaeueiiai noaio a?eo?ioeeo?a
aeaco? iie?ioaiiy ?o aa?aaaoe?eieo aeanoeainoae, ui i?aeoaa?aeaeo?
iiceoeaiee aieea iaia?aiinoaa?e?coth/i? oa?ai?? a ii?aeiaii? c
aeacaa?aaaoe?eiith oa a?iioaiceaiith oa?ai?yie ia noai i?e?ioee?eoeyoe??
i?e OAI. Oaeei /eiii, eiiiainaoe?y IIAEE i?ecaiaeeoue aei ciaioaiiy
u?eueiino? OE no?oeoo?, ii?iae?caoe?? i?iieeeeaino? oa cieaeaiith ??aiy
ia?ieneaeaoe?? e?i?ae?a, ui aacoiiaii iiceoeaii aieeaa? ia
ii?oiooieoe?iiaeuei? aeanoeainoe a?eo?ioeeo?a: ii?iae?co?oueny
i?iieeeea?noue, iie?ioo?oueny iai?i, caaania/o?oueny iaoaaie?/ia
?ioaeoi?noue ai?noo a?eo?ioeeoa.

I?ae aieeaii canoiniaaii? oa?ai?? a?aeaoaa?oueny /anoeiaa
a?aeiiaethaaiiy e?i?aeiiai a?neiy ieaciaoe/ii? iaia?aie, ui aaaea aei
iie?ioaiiy no?oeoo?iiai noaio ?ioaa?aeueieo a?ee?a, ye? o?nii iia’ycai?
c e?i?aeiei a?nei?i. C a?aeiiaeaiiyi e?i?aeiiai a?neiy iaia?aie
a?aeaoaa?oueny oaeiae noaa?e?caoe?y no?oeoo?e aaiiaeia?ia, ia ui
aeacothoue oaieio?ce/i? ia?aiao?e aeaiaoo?aoe?? aeaiiai a?eea.

?aiaee?oaaiiy nooiaith aeeiai?e? iieaciee?a neeaaeo AEE e?i?ae?a iaia?ai
a?eo?ioeeo?a i?ae aieeaii iaia?aiinoaa?e?coth/i? oa?ai?? (t-e??oa??e) o
oai?eo 1 oa 2 a?oi aeicaieeei ioe?ieoe eiiiainaoi?io aaao AEE. sse
?ai?oa a?aecia/aeinue, iaea?eueo iaoiaaiaoe/io aaaeeea?noue (t>2)
aeyaeee IIAEE — e?iieaaa, e?iieaiiaa, aeeicao?e?iiaa oa a?ao?aeiiiaa,
naia oe? AEE iaea?eueo aeoeaii aeeth/ai? ? a eiiiainaoi?i? i?ioeane
(oaae.1).

Oaaeeoey 1 — ???a?o?/ia cia/ei?noue (t-e?eoa??e) aeeiai?e? iieaciee?a
AEE neeaaeo i?ae aieeaii iaia?aiinoaa?e?coth/i? oa?ai??

A?oia oai?eoAEE

1 a?. OAI, OII 0 no.

/ieia?ee

n=23IIAEE

N 18:3(3,2)C 18:2(3,0)C 20:3(2,4)

C 20:4(1,9)C 16:1(1,5)C 17:1(0,5)

C 15:1(0)

IAEE

N 13:0(1,9)C 15:0(1,6)C 12:0(1,5)

C 17:0(1,2)C 16:0(1,1)C 14:0(0,9)

C 18:0(0,6)

1 a?. OAI, OII 0 no.

ae?iee

n=9IIAEE

N 18:3(3,6)C 16:1(3,5)C 20:3(1,9)

C 17:1(0,8)C 18:2(0,4)C 20:4(0,4)

C 15:1(0,2)

IAEE

N 18:0(2,5)C 17:0(1,6)C 13:0(1,4)

C 16:0(1,2)C 15:0(0,8)C 14:0(0,5)

C 12:0(0,1)

2 a?. OAI, OII I-II no.

/ieia?ee

n=14IIAEE

C 18:2(2,4)C 18:3(2,2)C 17:1(2,0)

C 20:4(1,7)C 16:1(1,6)C 20:3(1,3)

C 15:1(1,0)

IAEE

N 16:0(2,4)C 17:0(1,9)C 18:0(1,6)

C 14:0(1,5)C 13:0(1,4)C 15:0(1,1)

C 12:0(0,8)

2 a?. OAI, OII I-II no.

ae?iee

n=12IIAEE

C 20:4(3,5)C 18:3(2,8)C18:2(2,7)

C 15:1(1,6)C 20:3(0,9)C 16:1(0,7)

C 17:1(0,6)

IAEE

C 14:0(2,1)C 13:0(1,8)C 16:0(1,1)

C 18:0(0,9)C 12:0(0,8)C 17:0(0,7)

C 15:0(0,5)

Aiae?c nenoaiiooai?thth/eo iieaciee?a ei?aeyoe?eieo no?oeoo? i?ney
e?eoaaiiy anoaiiaea ciaioaiiy ?o nenoaiiooai?thth/eo iciae: 1 a?oia —
NAO, IIAEE (0,31)N 20:4/N 18:2 (0,30); 2 a?oia — NAO (2,76)e?aaoei?i
(2,73)IIAEE (1,26)N 20:4/N 18:2, na/iaeia (0,30), ui oaeiae aiai?eoue
i?i eiiiainaoi?iee aoaeo cae?enithaa?ii? oa?ai??. I?ioa, aeyaeaia a
oe?eiio iiceoeaia oa?aiaaoe/ia ae?y ia i?ecaiaeeoue aei iiaiiai
i?eai?/oaaiiy iaoiaaiaoe/ii? aeii?iaioe o ooieoe?iioaaii? nenoaie
i?aai?cio oai?eo ia OAI, ui aeaco? ia o?ii?/io oa/?th caoai?thaaiiy.
Aaaeeeaei aeieacii ia?aaiaeo ooieoe?iiaeueii? nenoaie i?aai?cio oai?eo
ia OAI c OII I-II noaae?? i?ney e?eoaaiiy c oace ooieoe?iiaeueiiai
iai?oaeaiiy aei oace no?eei? eiiiainaoe?? noa? ao?aoa aaaeo/i?
nenoaiiooai?thth/i? ?ie? i?aenenoaie e?aaoei?io ia ei?enoue i?aenenoai?
aaiiae?iai?ee.

Oai?? 3 a?oie, e??i aaiiae?ae?ca oa a?iioaiceaii? oa?ai?? io?eioaaee
i?aia?ao “Aaeeai?i”, a neeaae? yeiai i?noyoueny anaioe?aeuei?
ai?iieeneioe (L-a?a?i?i, L-a?noeaeei, L-e?cei). Caaaeueiee eo?n i?eeiio
i?aia?aoo neeaaeaa 30 ae?a: 20 ae?a i?aia?ao i?eeiaee ii 2 oaaeaoee 4
?ace ia aeiao, iio?i aeico i?aia?aoo cieaeoaaee aei 1 oaaeaoee 4 ?ace ia
aeiao ai?iaeiaae 10 ae?a. Iacaaaeath/e ia iiceoeaiee aieea eiiieaenii?
oa?ai?? ia ee?i?/i? iieacieee oa a?eo?iiiac, i?e aiae?c?
aee?iieeneioiiai noaio e?i?ae?a iaia?ai a?eo?ioeeo?a aeyaeaii
aeinoia??ia cieaeaiiy IAEE oa i?aeaeuaiiy IIAEE, iaeiae iaaeieoaeaiiy
aeao?oeeoo anaioe?aeueieo AEE i?e oeueiio ia a?aeaoaa?oueny.
I?aeoaa?aeaeaiiyi aeao?oeeoo IIAEE neoaeeoue oaiaeaioe?y e iacia/iiio
cieaeaiith ?i: o /ieia?e?a ia 3,6 % (p>0,05), o ae?iie ia 2,2 %
(p>0,05). Oaeei /eiii, iacaaaeath/e ia iiceoeaiee aio?aiai?/iee aoaeo
canoiniaaii? eiiieaenii? oa?ai?? caeeoa?oueny aenieiaeinoia??ia
(p<0,001) cieaeaiiy caaaeueiiai ai?noo AEE e?i?ae?a iaia?ai a?eo?ioeeo?a a?aeiinii eiio?iey oa aeao?oeeo IIAEE. AENIIAEE 1. Aeey oai?eo ia OAI oa?aeoa?ia iaiiaiioe?ii?noue aee?iieeneioiiai noaio e?i?ae?a iaia?ai a?eo?ioeeo?a oa ?o ooieoe?iiaeueia iani?iiiaei?noue, iaoiiaeaia aeao?oeeoii IIAEE; aaeain iaoiaaiaoe/ieo i?iya?a acioai?? c naiaaaiaoe/ieie iiaeeeainoyie aee?iieeneioiiai niaeo?o e?i?ae?a a?eo?ioeeoa?ieo iaia?ai ? aaaeeeaith neeaaeiaith aaaeeino? oa/?? OAI. 2. Aeao?oeeo IIAEE a?eo?ioeeoa?ieo iaia?ai iaoiiaeth? iaiao?aei?noue eiai iiiiaiaiiy, oae ye oe? AEE iathoue oeeoii?ioaeoi?io ae?th, aaaeeea? aeey neioaco aeeicaii?ae?a ? /anoeiai aecia/athoue aa?aaaoe?ei? aeanoeainoe a?eo?ioeeo?a. 3. Iaoiaeii ae?oa?aioe?aeueii-neai??oth/i? eaei??iao??? aeyaeaia ia?aaoaeiaa iaia?aiica’ycaieo a?ee?a oa a?eea, yeee ciaoiaeeoueny a na?aaeei? a?eo?ioeeoa, ui i?ecaiaeeoue aei ii?ooaiue o?ainii?oo eenith ? a?iien?? oeaiei. 4. Iaia?aiinoaa?e?coth/a oa?ai?y c canoinoaaiiyi “Anaioe?aea” a ii?aeiaii? c aeacaa?aaaoe?eiith oa a?iioaiceaiith oa?ai??e i?e OAI iiceoeaii aieeaa? ia aee?iieeneioiee noai e?i?ae?a iaia?ai oa aa?aaaoe?ei? aeanoeainoe a?eo?ioeeo?a. 5. Ci?ia e?i?aeiiai a?neiy iaia?ai a?eo?ioeeo?a, ca ?aooiie aeao?oeeoo IIAEE, i?e i?ecia/aii? “Anaioe?aea”, caaania/o? iaoaaie?/io ?ioaeoi?noue ai?noo a?eo?ioeeoo, i?i ui na?ae/aoue oaieio?ce/i? ia?aiao?e aeaiaoo?aoe?? aaiiaeiaeia a?eo?ioeeo?a i?ney e?eoaaiiy. 6. O oai?eo ia OAI, ye? ciaoiaeyoueny ia i?ia?aiiiio aaiiae?ae?c? i?ecia/aiiy i?aia?aoo “Aaeeai?i” aeicaiey? iie?ioeoe iieacieee a?eo?ioeeoa?iiai aaiinoaco oa ca?eueoeoe a?iiacioai?/iee aoaeo ai?iaaaeaeaiii? oa?ai??. 7. Cae?eniai? aeine?aeaeaiiy iaa?oioiaothoue aeioe?euei?noue canoinoaaiiy “anaioe?aeueieo” AEE o iaae?eaiaioicieo oi?iao o aeae? iiiioa?ai??, aai a eiia?iaoe?? c ?ioeie aeaeaie e?eoaaiiy i?e OAI, ui yaey? niaith aoaeoeaio i?aeo?eioth/o oa?ai?th i?e aeiia?oeiiao?eoao. I?AEOE*I? ?AEIIAIAeAOe?? 1. Aei ieaio eiiieaeniiai ianoaaeaiiy oai?eo ia OAI aeioe?eueii aeeth/aiiy aecia/aiiy aee?iieeneioiiai neeaaeo e?i?ae?a iaia?ai a?eo?ioeeo?a oa ?o aa?aaaoe?eieo aeanoeainoae, a oaeiae iaoiae?a, ye? aeicaieythoue aecia/eoe ci?ie aioo??ee?oeiieo a?ee?a ? a?ee?a ee?oeiieo iaia?ai a?eo?ioeeo?a. 2. A eiiieaen oa?iaeioa?aiaaoe/ieo cania?a i?e e?eoaaii? OAI c ??cieie noaae?yie OII ?aeiiaiaeo?oueny aeeth/aoe iaia?aiinoaa?e?coth/? i?aia?aoe (“Anaioe?aea”). 3. Aeey iineeaiiy a?iiacioai?/iiai aoaeoo eiiieaenii? oa?ai?? oai?eo c oa?i?iaeueiith ie?eiaith iaaeinoaoi?noth aeioe?eueii i?ecia/aiiy i?aia?aoo “Aaeeai?i”. 4. A eiiieaen oa?iaeioa?aiaaoe/ieo cania?a, ye? iie?ioothoue iieacieee a?eo?ioeeoa?iiai aaiinoaco oai?eo c OII ?aeiiaiaeo?oueny aeeth/aoe i?aia?aoe, ye? iaaeieoaeothoue aeao?oeeo iacai?iieo AEE (“Anaioe?aea”) ? iacai?iieo ai?iieeneio (“Aaeeai?i”). NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. Oii/ee E.E., Ianai A.A., Cei/aiei A.A., Nieiaueaaa A.N. Eaei?eiao?e/aneia enneaaeiaaiea iaia?ai y?eo?ioeeoia /aeiaaea i?e aeiia?oeiiao?eoao // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.-1997.-? 27.-N.156-163. 2. Ianai A.A. Eeeie/aneay yooaeoeaiinoue i?aia?aoa Aaeeaiei a ea/aiee aieueiuo o?iie/aneei aeiia?oeiiao?eoii a oa?ieiaeueiie noaaeee o?iie/aneie ii/a/iie iaaeinoaoi/iinoe // Oa?iaeii.-1998.-? 6.-N.58-62. 3. Ianai A.I. Aieea i?aia?aoo “Anaioe?aea” ia ai?no iie?iaiane/aieo aee?ieo eeneio iaia?ai a?eo?ioeeo?a o oai?eo ia aeiia?oeiiao?eo // Ee?i?/ia oa?iaoe?y.-1998.-o.2, ? 1.-N.51-53. 4. Ianai A.I. Oa?iaeioa?aiaaoe/ia ae?y i?aia?aoo “Aaeeai?i” i?e o?ii?/i?e ie?eia?e iaaeinoaoiino? // Ee?i?/ia oa?iaoe?y.-1998.-o.2, ? 3.-N.37-38. 5. Oii/ee E.E., Ianai A.A. Yooaeoeaiinoue aeaenoaey i?aia?aoia “Aaeeaiei” e “Eaniaoeai” i?e o?iie/aneie ii/a/iie iaaeinoaoi/iinoe // Nia?aiaiiua i?iaeaiu eeeieee aioo?aiieo aieaciae: Na. iao/. o?. -Oa?ueeia: ?EI “I?eaeiae”, 1997. – N.269-271. 6. Ianai A.A. Oa?iinoaaeeueiinoue iaia?ai y?eo?ioeeoia i?e aeiia?oeiiao?eoao n ?acee/iie noaiaiueth o?iie/aneie ii/a/iie iaaeinoaoi/iinoe // Nia?aiaiiua i?iaeaiu eeeieee aioo?aiieo aieaciae: Na. iao/. o?. -Oa?ueeia: ?EI “I?eaeiae”, 1997. – N.275-279. 7. Oii/ee E.E., Ianai A.A. AEe?iieeneioiue ninoaa oinoieeieaeia y?eo?ioeeoa?iuo iaia?ai o aieueiuo ainiaeeoaeueiuie caaieaaaieyie ii/ae a aeeiaieea ea/aiey // Iaoa??aee iaoeiaeo i?aoeue ?anioae?eainueei? iaoeiai-i?aeoe/ii? eiioa?aioe?? “?ieue caaaeueiii?aeoeeoth/iai e?ea?y o ?ica’ycaii? i?iaeai i?io?eaeoeee ia?ioaeoe?eieo caoai?thaaiue”, 19-20 eenoiiaaea 1997 ?. – Oa?e?a, 1997.-N.93. 8. Oii/ee E.E., Eiaca?ue A.E., Ianai A.A. Eciaiaiea aee?iieeneioiiai niaeo?a iaia?ai y?eo?ioeeoia iiae aeeyieai iaia?aiinoaaeeece?othueo i?aia?aoia // ?anioaeeeaineay iao/ii-i?aeoe/aneay eiioa?aioeey iieiaeuo o/aiuo e niaoeeaeenoia “Nia?aiaiiua ooiaeaiaioaeueiua e i?eeeaaeiua i?iaeaiu eeeieee aioo?aiieo aieaciae”, 17 ai?aey 1997 a. – Oa?ueeia, 1997.-N.75-76. 9. Oii/?e ?.?., Ianai A.I., Eiaca?ue A.?., Eiooeaa?/ I.ss. Ci?ie aee?iieeneioiiai neeaaeo a?eo?ioeeoa?ieo iaia?ai o oai?eo ia iao?eo i?e e?eoaaii? c canoinoaaiiyi aaiiae?ae?ca, i?aia?ao?a “Aaeeai?i”, “Eaniaoeai” oa “Anaioe?aea” // Iaoa??aee XIV c’?caeo oa?aiaao?a Oe?a?ie. – Ee?a, 1998.-N.137. 10. Iaoaio ia aeiao?ae “Niin?a aeeoa?aioe?aeueii? ae?aaiinoeee neiioiiaoe/ii? ?aiiia?aio?iaoicii? oa anaioe?aeueii? a?ia?oii?e” (ni?aaao. A.N.Eiiueeiaa) – ?a?no?aoe?eiee iiia? cayaee: 97062749, aeaoa iiaeaiiy 10.06.97; i?eeiyooy ??oaiiy 13.04.98. Ianai A.I. AEe?iieeneioiee neeaae e?i?ae?a iaia?ai a?eo?ioeeo?a oai?eo ia o?ii?/iee aeiia?oeiiao?eo a aeeiai?oe? e?eoaaiiy.- ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02 – aioo??oi? oai?iae. – Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Oa?e?a, 1999. Aeena?oaoe?th i?enay/aii aea/aiith aieeao eiiieaenii? oa?ai?? ia aee?iieeneioiee noai e?i?ae?a iaia?ai a?eo?ioeeo?a oa ?o aa?aaaoe?ei? aeanoeainoe o oai?eo ia o?ii?/iee aeiia?oeiiao?eo. Aeanoaa?e?caoe?y ee?oeiieo iaia?ai iia’ycaia c noeioeyoe??th ia?aeeniiai ieeneaiiy e?i?ae?a, noano?aoii yeiai ? iaiane/ai? aee?i? eeneioe o neeaae? oinoie?i?ae?a, ui i?ecaiaeeoue aei “?iciooaiino?” iaia?ai, i?aeaeuaiith i?iieeeeaino? ? a e?ioeaaiio ?aooieo aei ii?ooaiue ?o ?ioaa?aeueii? oe?einiino?. O oai?eo ia o?ii?/iee aeiia?oeiiao?eo anoaiiaeaii cieaeaiiy ai?noo anaioe?aeueieo aee?ieo eeneio (e?iieaai?, e?iieaiiai? oa a?ao?aeiiiai?) o ii??aiyii? c eiio?ieai; i?ney e?eoaaiiy aoei aeyaeaii ca?eueoaiiy ai?noo aeaieo eeneio a a?eo?ioeeoa?ieo iaia?aiao. Aeine?aeaeaiiy aeicaiey? ?aeiiaiaeoaaoe aeei?enoaiiy iaia?aiinoaa?e?coth/eo i?aia?ao?a, ye? i?noyoue anaioe?aeuei? aee?i? eeneioe, aeey e?eoaaiiy oai?eo ia aeiia?oeiiao?eo. I?iaaaeaia aeine?aeaeaiiy aeyaeei, ui i?aia?ao “Aaeeai?i” /eieoue a?iiacioai?/io, aiaaie?/io oa aio?aiai?/io ae?th ? iiaea aooe ?aeiiaiaeiaaiee oai?ei c o?ai??th. Eeth/ia? neiaa: o?ii?/iee aeiia?oeiiao?eo, o?ii?/ia ie?eiaa iaaeinoaoi?noue, aaiiae?ae?c, a?eo?ioeeoe, a?eo?ioeeoa?ia iaia?aia, aee?i? eeneioe, aa?aaaoe?y a?eo?ioeeo?a, oinoie?i?aee, ia?aeenia ieeneaiiy e?i?ae?a. Ianai A.A. AEe?iieeneioiue ninoaa eeieaeia iaia?ai y?eo?ioeeoia o aieueiuo o?iie/aneei aeiia?oeiiao?eoii a aeeiaieea ea/aiey - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02 – aioo?aiiea aieacie. – Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Oa?ueeia, 1999. Aeenna?oaoeey iinayuaia eco/aieth aeeyiey eiiieaeniie oa?aiee ia aee?iieeneioiue ninoaa eeieaeia iaia?ai y?eo?ioeeoia e eo aa?aaaoeeiiiuo naienoa o aieueiuo o?iie/aneei aeiia?oeiiao?eoii. Aeanoaaeeecaoeey eeaoi/iuo iaia?ai naycaia ni noeioeyoeeae ia?aeeniiai ieeneaiey eeieaeia, noano?aoii eioi?iai yaeythony iaianuuaiiua aee?iua eeneiou a ninoaaa oinoieeieaeia, /oi i?eaiaeeo e ia?ooaieth eo eioaa?aeueiie oeaeinoiinoe. Ia?ooaiea no?oeoo?ii-ooieoeeiiaeueiie i?aaiecaoeee eeaoi/iuo iaia?ai yaeyaony iniiaiiieaaathuei oaeoi?ii ?aaeecaoeee oeaeiai ?yaea iaoieiae/aneeo ninoiyiee, a oii /enea aeiia?oeiiao?eoa. Y?eo?ioeeou i?aaenoaaeytho niaie oieaa?naeueioth iiaeaeue ieaciaoe/aneie iaia?aiu. Eco/aiea ninoaaa AEE eeieaeia iaia?ai y?eo?ioeeoia yaeyaony aeooaeueiui, iineieueeo iie yaeythony ia oieueei iaeaieaa oycaeiui caaiii iaia?aiiuo eeieaeia, ii e aunooiatho i?aaeoanoaaiieeaie aeieiae/anee aeoeaiuo aauanoa. Aaaeiie i?e/eiie eco/aiey ninoaaa AEE eeieaeia iaia?ai y?eo?ioeeoia yaeyaony eo aaiieec – eae iaeia ec i?e/eie aiaiee i?e o?aiee. Iaiaoiaeeiinoue aeeeoaeueiiai iaaeeeaiaioiciiai ea/aiey OAI nii?yaeaia n ?eneii ?acaeoey na?ueaciuo iiai/iuo yaeaiee e ineiaeiaiee. Aeeyiea i?iaiaeeiie oa?aiee ia eiee/anoaaiiue e ea/anoaaiiue ninoaa AEE eeieaeia y?eo?ioeeoa?iuo iaia?ai aieueiuo OAI iiaeao niinianoaiaaoue oniaa?oainoaiaaieth ea/aiey OAI, a oai naiui – oiaiueoaieth iiai/iuo yaeaiee e iiauoaieth yooaeoeaiinoe oa?aiee. A oiaea auiieiaiey ?aaiou ianeaaeiaaii 106 /aeiaae: 88 aieueiuo OAI e 18 /aeiaae – a?oiia n?aaiaiey (i?aeoe/anee caei?iaua eeoea) a aic?anoa io 20 aei 60 eao (n?aaeiee aic?ano (43,3+3,7) aiaea), aieueiua auee ?ani?aaeaeaiu ia 3 iniiaiua a?oiiu. Anai aieueiui auei i?iaaaeaii eiiieaeniia eeeie/aneia ianeaaeiaaiea a oneiaeyo Einoeoooa oa?aiee. Aeiiieieoaeueii auiieiyeenue neaaeothuea iaoiaeeee: aacio?iiaoia?aoe/aneee aiaeec AEE eeieaeia iaia?ai y?eo?ioeeoia; ii?aaeaeaiea eiaeooee?iaaiiie aa?aaaoeee y?eo?ioeeoia oioiyeaeo?ieiei?eiao?e/aneei iaoiaeii; aeeooa?aioeeaeueii-neaie?othuay eaei?eiao?ey (AeNE) eciee?iaaiiuo iaia?ai y?eo?ioeeoia. I?e eco/aiee ninoaaa AEE iaia?ai y?eo?ioeeoia o/eouaaeny iieiaie aeeii?oeci. I?e aiaeeca i?ioeaioiiai niaea?aeaiey eaaeaeie AEE a niaeo?a aunaaaaiuo AEE ai anao o?ao a?oiiao ia oiia nieaeaiey i?ioeaioiiai niaea?aeaiey iaianuuaiiuo AEE ioia/aaony iiauoaiea i?ioeaioiiai niaea?aeaiey ianuuaiiuo AEE. Iniaaiii y?ei aeaiiia eciaiaiea au?aaeaii a AEE ninoaaa iaia?ai y?eo?ioeeoia o aieueiuo n oa?ieiaeueiie noaaeeae OII. O aeaiuei, eae e o ioae/ei nio?aiyaony oa aea oaiaeaioeey. Iaeiaei oiaiueoaiea iaianuuaiiuo AEE o aeaiuei au?aaeaii ia noieue cia/eoaeueii, eae o ioae/ei, /oi iauyniyaony caueoiui aeaenoaeai aeaineeo iieiauo ai?iiiia (yno?aaeeie e i?iaanoa?ii), eioi?ua yaeythony aeiaioeieneaeaioaie. Yoa ?acieoea naeaaeeaaaony o aieueiuo 3 a?oiiu. Aeey eco/aiey aaeie - eeieaeiuo acaeiiaeaenoaee e ninoiyiey aaiiaeiaeia eniieueciaaee iaoiae AeNE. Auee iieo/aiu ioee/athueany iaaeaeo niaie eaei?eiao?e/aneea i?ioeee oaiia?aoo?iuo ia?aoiaeia. Iaeaieueoei eciaiaieyi iiaeaa?aeaiu eioaa?aeueiua aaeee (ia?aoiaeu A e N), iia?oaeaiiua a eeieaeiue aeneie, /oi iiaeoaa?aeaeaao iaee/ea eciaiaiee a no?oeoo?a eeieaeia. Ia?aoiaeu A e D (no?oeoo?iua aaeee) – i?aeoe/anee ia eciaiaiu. I?e eco/aiee ninoiyiey aaeea aaiiaeiaeia ioia/aii nieaeaiea oaieiaiai yooaeoa aai aeaiaoo?aoeee, /oi naeaeaoaeuenoaoao i ia?ooaiee i?ino?ainoaaiiie no?oeoo?u aeaiiie iieaeoeu. Iineieueeo niaoeeoe/aneeo iaoiaeia oa?aiee OAI iiea ia nouanoaoao, e ie iaeei ec i?eiaiythueony iaoiaeia e n?aaenoa ia aeaao aa?aioee iieiiai aucaei?iaeaiey – iniiaiie oeaeueth i?e ea/aiee OAI yaeyaony caiaaeeaiea oaiiia i?ia?anne?iaaiey caaieaaaiey e i?aaeoi?aaeaeaiey ?acaeoey OII. Aieueiua 1 e 2 eeeie/aneeo a?oii iieo/aee aeiioaiceaiua n?aaenoaa e aeacaa?aaaiou, a ea/anoaa iaia?aiinoaaeeece?othuaai n?aaenoaa eniieueciaaeny i?aia?ao “Ynnaioeeaea” a ninoaa eioi?iai aoiaeyo eeiieaaay e eeiieaiiaay eeneiou. Iinea i?iaaaeaiiiai eo?na ea/aiey ia oiia oeo/oaiey iauaai ninoiyiey ioia/aeinue iiauoaiea i?ioeaioiiai niaea?aeaiey iieeiaianuuaiiuo AEE eae o ioae/ei, oae e o aeaiuei. Eiiiainaoeey iieeiaianuuaiiuo AEE i?eaiaeeo ia oieueei e oeo/oaieth eiee/anoaaiiiai e ea/anoaaiiiai ninoaaa AEE, ii e e oeo/oaieth ooieoeeiiaeueiuo naienoa y?eo?ioeeoia, i /ai naeaeaoaeuenoaotho iieacaoaee aa?aaaoeeiiiuo naienoa y?eo?ioeeoia. Aieueiua 3 a?oiiu, e?iia aaiiaeeaeeca e aeiioaiceaiie oa?aiee iieo/aee i?aia?ao “Aaeeaiei”, a ninoaa eioi?iai aoiaeyo ynnaioeeaeueiua aieiieeneiou (L-a?aeiei, L-aenoeaeei, L-eecei). Ianiio?y ia iieiaeeoaeueiia aeeyiea ia y?eo?iiiyc i?e aiaeeca AEE ninoaaa eeieaeia iaia?ai y?eo?ioeeoia ioia/aaony aeinoiaa?iia nieaeaiea ianuuaiiuo AEE e iiauoaiea iaianuuaiiuo AEE, iineieueeo aenoeaeei yaeyaony anoanoaaiiui eiaeaeoi?ii ?aniaaea ia?aeenae AEE e ia?aie/eaaao ia?aciaaiea i?iaeoeoia IIE, a /anoiinoe, iaeiiiaiai aeeaeueaeaaeaea. Iaeiaei, ainiieiaiea aeaoeoeeoa ynnaioeeaeueiuo AEE ia i?ienoiaeeo, eae o ioae/ei, oae e o aeaiuei. Iiyoiio anee i?eiyoue ai aieiaiea iaee/ea nio?aiythueony o aieueiuo aeaiiie a?oiiu iaiieiioeaiiinoe eeieaeiiai ninoaaa y?eo?ioeeoa?iuo iaia?ai e, neaaeiaaoaeueii, eo ii?aaeaeaiioth ooieoeeiiaeueioth ianinoiyoaeueiinoue – i?aaenoaaeyaony oeaeaniia?aciui iacia/aiea iaia?aiinoaaeeece?othuae oa?aiee o aieueiuo aeaiiie a?oiiu. Iiaeoaa?aeaeaieai yooaeoeaiinoe i?iaiaeeiie oa?aiee neoaeeo i?iaaaeaiiue nenoaiiue aiaeec. Enneaaeiaaiea iicaieyao ?aeiiaiaeiaaoue eniieueciaaiea iaia?aiinoaaeeece?othueo i?aia?aoia, eioi?ua niaea?aeao ynnaioeeaeueiua aee?iua eeneiou, aeey ea/aiey aieueiuo aeiia?oeiiao?eoii. I?iaaaeaiiia enneaaeiaaiea auyaeei, /oi i?aia?ao “Aaeeaiei” ieacuaaao aeiiacioaie/aneia, aiaaiee/aneia e aioeaiaie/aneia aeaenoaea e iiaeao auoue ?aeiiaiaeiaai aieueiui n o?aieae. Eeth/aaua neiaa: o?iie/aneee aeiia?oeiiao?eo, o?iie/aneay ii/a/iay iaaeinoaoi/iinoue, aaiiaeeaeec, y?eo?ioeeou, iaia?aia y?eo?ioeeoa, aee?iua eeneiou, aa?aaaoeey y?eo?ioeeoia, oinoieeieaeu, ia?aeeniia ieeneaiea eeieaeia. Nesen A.A. The aliphatic acidic spectrum of lipides of membranes red blood cell in patients with glomerulonephritis in dynamics of treatment. – Manuscript. Dissertation for competition of scientific degree of candidate of medicine, specialization 14.01.02 – internal disease. – Kharkov state medical university, Kharkov, 1999. Thesis in which are analyzed effects of integrated therapy on changes in content of fatty acids in red blood cell membranes and red blood cell aggregation properties in patients with glomerulonephritis. Destabilization in cell membranes is due to stimulation of lipid peroxidation, unsaturated fatty acids in composition of phospholipides being a substract of this peroxidation which results in “loosening” of membranes, an increased permeability and, finely, disturbance of their integrity. In patients with chronic glomerulonephritis the content of essential fatty acids (linoleic, linolenic and arachidonic) is decreased in comparison to the control; after treatment the content of these acids in red blood cell membranes is increased. The received results allow to recommend using of membrane stabilizers containing essential fatty acids for treatment of glomerulonephritis. Our study suggests that “Baicamin” exerts hypoazotemic, anabolic and antyanemic effects and might be prescribed to patients with uremia. Key words: chronic glomerulonephritis, chronic renal failure, hemodialysis, red blood cell, erythrocyte membrane, fatty acids, red blood cell aggregation, phospholipid, lipid peroxidation. NIENIE NEI?I*AIUe AeAAe- ae?anoie?/iee a?oa??aeueiee oeneAeNE- aeeoa?aioe?aeueii-neai??oth/a eaei?eiao??yAEE- aee?i? eeneioe?i- ?iaeaen iane/aiino?IAEE- iane/ai? aee?i? eeneioeIIAEE- iaiane/ai? aee?i? eeneioeIA- i?inoaaeaiaeeieIIAEE- iie?iaiane/ai? aee?i? eeneioeIIE- ia?aeenia ieeneaiiy e?i?ae?a?E- ?aiaeueiee eiao?oe??io?E?- ?aiaeueii-ei?oeeaeueiee ?iaeaenNAAe- nenoie?/iee a?oa??aeueiee oeneOE- oinoie?i?aeeOAAe- o?ii?/iee aaiiae?ae?cOAI- o?ii?/iee aeiia?oeiiao?eoOII- o?ii?/ia ie?eiaa iaaeinoaoi?noue

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