I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

OE?A?INUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO EA?Ae?IEIA?? ?i. aeaae.
I.Ae.NO?AAEANEA

AOAIANIAA Iaoae?y A?eoi??aia

OAeE 616.127-005.8.-036.11-036.8286:612.173.1

?AIIss IINO?IOA?EOIA NOAIIEA?Ae?ss: EE?I?*IA OA?AEOA?ENOEEA,
OOIEOe?IIAEUeI? INIAEEAINO?, A?AeIIAEAIIss I?AOeACAeAOIINO?

14.01.11 — ea?ae?ieia?y

A a o i ? a o a ? a o

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Oe?a?inueeiio iaoeiai-aeine?aeiiio ?inoeooo?
ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea IIC Oe?a?ie

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee
ni?a?ia?oiee Ooiaeia Aaeaioei Ieaenaiae?iae/, Oe?a?inueeee
iaoeiai-aeine?aeiee ?inoeooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea
IIC Oe?a?ie, caa?aeoaa/ a?aeae?eaiiy aino?iai ?ioa?eoo i?iea?aea oa
a?aeiiethaaeueiiai e?eoaaiiy

Io?oe?ei? iiiiaioe: — aeieoi? iaaee/ieo iaoe, aeaaeai?e AII Oe?a?ie,
/eai-ei?. IAI Oe?a?ie ? AII ?in??, i?ioani? Ei?eooei Ieaa Aaneeueiae/,
?inoeooo aa?iioieia?? AII Oe?a?ie, ea??aiee a?aeae?eo ee?i?/ii?
o?c?ieia?? oa iaoieia?? aioo??oi?o i?aai?a

-aeieoi? iaaee/ieo iaoe A?eiiiaeei Ieaenaiae? Aai?a?eiae/, Ee?anueea
iaaee/ia aeaaeai?y i?ney-aeeieiiii? ina?oe ?i. I.E. Ooi?ea IIC Oe?a?ie,
i?ia?aeiee iaoeiaee ni?a?ia?oiee i?iaeaiii? eaai?aoi??? aia?ia?ao?/ieo
oa aeaeo?io?c?ieia?/ieo aeine?aeaeaiue eaoaae?e ea?ae?ieia?? oa
ooieoe?iiaeueii? ae?aaiinoeee

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i.
I.I.Aiaiiieueoey, eaoaae?a aini?oaeueii? oa?ai?? ? 1, IIC Oe?a?ie, i.
Ee?a

Caoeno aeena?oaoe?? a?aeaoaeaoueny 16 ethoiai 1999 ?ieo i 11-00 aiaeei?
ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.616.01 Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea
(252151, Ee?a, aoe. Ia?iaeiiai iiie/aiiy, 5)

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea
(252151, Ee?a, aoe. Ia?iaeiiai iiie/aiiy, 5)

Aaoi?aoa?ao ?ic?neaiee 15 n?/iy 1999 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Aeaye N.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. I?iaeaia aino?iai ?ioa?eoo i?iea?aea (A?I)
eeoa?oueny iaei??th c iaea?eueo aeooaeueieo a no/ani?e ea?ae?ieia??, ia
aeeaey/enue ia cia/i? aeinyaiaiiy a ae?aaiinoeoe? oa e?eoaaii? oai?eo a
inoaii? aeanyoe??//y (Antoniucci D.,1998, Barbagelata A. et al.,1995,
Gill J.B. et al.,1996, Jesperson C. et al., 1997, Ohman E.M. et
al.,1993, Rogers W.J. et al.,1995, Yun D.D. et al.,1997).

Na?aae neiae?ii?a, ui oneeaaeiththoue ia?aa?a A?I, a inoaii? ?iee
caeiiii??io caoe?eaaeai?noue aeeeeea? iino?ioa?eoia noaiiea?ae?y,
iniaeeai ?? ?aiiy oi?ia. I?ae neiae?iiii ?aiiuei? iino?ioa?eoii?
noaiiea?ae?? (?IN) ?icoi?thoue a?aeiiaeaiiy aia?iicieo i?enooi?a o
no?iee a?ae 6 aiaeei aei 3-4 oeaei?a c iiiaioo ?icaeoeo A?I (Campolo L.
et al.,1986, De Servi S. et al.,1986, Fioretti P. et al.,1986, Galjii
M.,1993, Ouyang P. et al.,1991, Schuster E.N. et al.,1981).
Aaaaoi/eneaii? aeine?aeaeaiiy iieacaee, ui ia aeeaey/enue ia aeoeaio
iaaeeeaiaioicio oa?ai?th a ia??iae A?I, /anoioa ?icaeoeo ?IN eeoa?oueny
a iaaeao 15-30%. A 89% aeiaaeeao ?IN ?icaeaa?oueny o oai?eo c
aaaaoinoaeeiiei o?aaeaiiyi ei?iia?iiai ?onea, iaiiaiioe?iiei
eieaoa?aeueiei e?iaiia?aii, iayai?noth o?iiao a ?ioa?eo-caeaaei?e
a?oa???.

Neiae?ii ?IN cia/ii iia??oo? i?iaiic oai?eo: aaea ia aini?oaeueiiio
aoai? o 20% oai?eo c ?IN ?icaeaathoueny ?aoeeaeeae ?ioa?eoo i?iea?aea, a
aei e?ioey ia?oiai ?ieo /anoioa iiaoi?ieo A?I c?inoa? aei 50%. Oi/a
inoaoi/iiai cia/aiiy ?IN a ?icaeoeo ea?ae?aeueii? nia?o? oa ?a?ioa?eo?a
iaa?aeiia, a aeayeeo aeine?aeaeaiiyo i?iaeaiiino?iaaii nooo?aa
ca?eueoaiiy nia?oiino? ? /anoioe ?a?ioa?eo?a c 17% aei 56% oa c 10% aei
33%, a?aeiia?aeii (Bigger J.T.,1986, De Servi S. et al.,1986, Dwyer E.
et al.,1984). E??i oiai, /anoioa ?IN a oeeo aeine?aeaeaiiyo aa??thaaea
a?ae 6% aei 33% (Bosch X. et al.,1987, Campolo L. et al.,1986, Fioretti
P. et al.,1986, Figueras J. et al.,1983, Sellier P. et al.,1988).
Aeei?enoaiiy ia nueiaiaei?oi?e aeaiue aeey e?eoaaiiy oai?eo c ?IN
aioo??oiueiei?iia?iiai o?iiaie?c?no, ai?oiei?iia?iiai ooiooaaiiy,
o?ainethi?iaeueii? aia?iieanoeee aeicaieeei, a iaai?e i???, iie?aueoe
i?iaiic oe??? a?oie oai?eo (Aa?e?iaa?a N.O.,1993, ?inae?ai? Ae.A. ?
ni?aaao.,1989, Nieia’?ia A.I. ? ni?aaao.,1990, Kjekhus J. et al.,1995,
Lee L. et al.,1988, Molina L. et al.,1983).

A?aoiaoth/e aenieee ?ecee iaaeaaii?e?iiiai ia?aa?ao caoai?thaaiiy o
oai?eo c ?IN, oe?eeii c?icoi?ea oa oaaaa, yeo ee?i?oeenoe i?eae?eythoue
aeaiiio neiae?iio. Ii?yae c oeei ?nio? aaaaoi ieoaiue, ye? aeiaaathoue
?ica’ycaiiy, cie?aia, a?aenooi? ia’?eoeai? ee?i?ei-ae?aaiinoe/i?
e?eoa???, ?niothoue neeaaeiino? o aeai?? iaoiaaiaoe/ii iaa?oioiaaiiai
e?eoaaiiy, ia ?ica’ycai? aniaeoe ?aaa?e?oaoe?eiiai oa?aeoa?o aecia/aiiy
ieoaiue i?aoeacaeaoiino?. Aeuaaeeeaaeai? iaae??oai? i?iaeaie oai?eo c
?IN noaee i?aea?oioyi aeey i?iaaaeaiiy oaia??oiueiai aeine?aeaeaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa “?aiiy iino?ioa?eoia noaiiea?ae?y: ee?i?/ia oa?aeoa?enoeea,
ooieoe?iiaeuei? iniaeeaino?, a?aeiiaeaiiy i?aoeacaeaoiino?” Aoaianiai?
I.A. aeeiioaaeanue a ?aieao iaoeiai? oaiaoeee a?aeae?eyiiy aino?iai
?ioa?eoo i?iea?aea oa a?aeiiaethaaeueiiai e?eoaaiiy “Aea/eoe iniaeeaino?
aaiiaeeiai?/ieo c?ooaiue i?e iino?ioa?eoi?e noaiiea?ae?? c iaoith
iioei?caoe?? cania?a e?eoaaeueieo ? ?aaa?e?oaoe?eieo caoiae?a”, ?
aea?aeaaii? ?a?no?aoe?? IE 17.0000.107.96.

Iaoa ? caaea/? aeine?aeaeaiiy. Anoaiiaeoe ee?i?ei-ooieoe?iiaeuei?
e?eoa??? ia’?eoea?caoe?? noaio oai?eo c ?IN ia iniia? aea/aiiy
ee?i?/iiai ia?aa?ao caoai?thaaiiy, iniaeeainoae ooieoe?iiaeueiiai noaio
i?iea?aea oa ei?iia?iiai ?aca?ao. ?ic?iaeoe ee?i?ei-ae?aaiinoe/i?
i?aeoiaee, oa?aiaaoe/io oaeoeeo aaaeaiiy oai?eo c ?IN oa iieacaiue aei
aecia/aiiy no?ie?a iai?aoeacaeaoiino?. Aeey aeinyaiaiiy iaoe aoee
iinoaaeai? ianooii? caaea/?:

· aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao ?IN;

· ioe?ieoe ooieoe?iiaeueiee noai i?iea?aeo e?aiai oeoii/ea oa inoaoi/ii?
i?aoeacaeaoiino? ca aeaieie aoiea?ae?ia?ao?? oa i?iae c aeiciaaiei
o?ce/iei iaaaioaaeaiiyi;

· aecia/eoe oa?aeoa? o?aaeaiiy ei?iia?ieo noaeei ca ?acoeueoaoaie
ei?iia?iaia?ia?ao??;

· anoaiiaeoe iniaeeaino? iieaciee?a Oieoa??anueeiai iii?oi?oaaiiy o
oai?eo c ?IN;

· aea/eoe aeaye? iieacieee noaio a?ieia?/ii aeoeaieo nenoai o oai?eo c
?IN;

· a caeaaeiino? a?ae io?eiaieo ?acoeueoao?a aecia/eoe iaea?eueo
?aoe?iiaeueiee i?aeo?ae aei e?eoaaiiy.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa aeae?eai? ??ci?
aa??aioe ia?aa?ao ?IN c aecia/aiiyi ?o ooieoe?iiaeueieo oa
ii?oieia?/ieo oa?aeoa?enoee. Anoaiiaeaia cia/ei?noue aeey ?IN
aacinianoe/ii? ?aaeoe??, a oaeiae ?ieue a?oa??aeueii? a?ia?oaic??,
aaee/eie o?aaeaiiy oa e?aoiino? ?ioa?eoo i?iea?aeo. Anoaiiaeaia
iaiaeii??aei?noue o?aaeaiiy noaeeiiiai ?onea oa ??aiy a?aeiiaeaiiy
inoaoi/ii? i?aoeacaeaoiino? a caeaaeiino? a?ae aeae?eaieo aa??aio?a ?IN.

A?eueo iecueea a?aeiiaeaiiy inoaoi/ii? i?aoeacaeaoiino? o oai?eo c?
noaa?eueiith noaiiea?ae??th, ui ia?aaeo? A?I oa ??aee? o?aaeaiiy
aeenoaeueieo a?aeae?e?a ei?iia?ieo a?oa??e aeicaiey? aaaaeaoe oeae
eiioeiaaio iaea?eueo iieacaiei aei o??o?a?/ieo ao?o/aiue.

Iaaeeeaiaioicia e?eoaaiiy iaea?eueo aoaeoeaia o in?a c? noaiiea?ae??th,
ui aia?oa aeieeea i?ney A?I, o yeeo iiaeeeaa i?aeaeuaiiy
i?aoeacaeaoiino? aei ??aiy I ooieoe?iiaeueiiai eeano. A?aoiaoth/e, ui o
50% oeeo oai?eo ciaeaeai? aeenoaeuei? oa iaeiinoaeeii? o?aaeaiiy
ei?iia?ieo a?oa??e i?e ei?iia?iaia?ia?ao??, i?iaaaeaiiy o??o?a?/iiai
e?eoaaiiy aeaii? eaoaai??? iaoe??io?a iio?aao? iaiaeiicia/iiai ??oaiiy.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Aeae?eai? ee?i?/i? a?oie c
?IN, a yeeo aeinyaioo aoaeo i?e eiina?aaoeaiiio e?eoaaii?, yea
aeinoaoiuei aeey a?aeiiaeaiiy i?aoeacaeaoiino? ia ??ai? eaaei? ?iaioe.

Aecia/ai? iaaeaaii?e?ii? iciaee aeey i?aeaeuaiiy caeeoeiai?
i?aoeacaeaoiino? ?, ye iane?aeie, e?eoa??? iai?aaeaiiy oeeo oai?eo ia
o??o?a?/io ei?aeoe?th.

Iieacaia aeioe?euei?noue i?iaaaeaiiy OI o oai?eo A?I aac ?IN.

Aeyaeaiiy iaeneioio i?iea?ae?aeueii? ?oai?? o oai?eo 1 a?oie a ?aieia?
aiaeeie aeeeoo? iaiao?aei?noue i?ecia/aiiy ?i ?ai?oi?o i?eeii?a
i?aia?ao?a c iaoith iiia?aaeaeaiiy neiae?iio “?icoiaeaeoaaiiy”.

Nooo?aa ?ieue ooieoe?iiaeueiiai oaeoi?o a aaiac? ?IN, ui i?aeoaa?aeaeaia
aeieeiaiiyi i?iea?ae?aeueii? ?oai?? a i?/i? aiaeeie oa ci?iaie
iieaciee?a noaio a?ieia?/ii aeoeaieo nenoai aeeeoo? iaiao?aei?noue
aeeoa?aioe?eiaaiiai i?aeoiaeo aei e?eoaaeueii? oaeoeee oa
oa?iaeieia?/iiai e?eoaaiiy.

Iniiai? ?acoeueoaoe aeena?oaoe?? ai?iaaaeaeai? a i?aeoeeo
ea?ae?ieia?/ieo a?aeae?eaiue Aieeinueei? iaeanii? ee?i?/ii? e?ea?i? (i.
Eooeuee), IAe? “Iaaeeoeeia o?ainii?oo” (i. Iaeana), Oeaio?aeueii?
ee?i?/ii? o?ainii?oii? e?ea?i? (i. Ee?a), i?i ui na?ae/aoue aeoe
ai?iaaaeaeaiiy.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii iniaenoi i?iaiaeeeenue
ee?i?ei-ooieoe?iiaeuei? aeine?aeaeaiiy, ye? aeeth/aee ?aoaeueiee aiae?c
ee?i?/iiai ia?aa?ao oai?iae, aeeiiaiiy aoiea?ae?ia?ao??, aaeia?aiiao???.
Naiino?eii aoea caaaeaia aaca aeaieo, i?iaaaeai? ocaaaeueiaiiy ?
noaoenoe/ia ia?iaea ?acoeueoao?a aeine?aeaeaiiy, i?aeaioiaeai? iaoeia?
aeaii? aei ioae?eaoe??, caeeth/ia ioi?ieaiiy aeena?oaoe?eii? ?iaioe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aoee aeeeaaeai? a iaoa??aeao ? c’?caeo ea?ae?ieia?a Iieaeiae (Eeoei?a,
aeiaoaiue, 1996), iaoeiai-i?aeoe/ii? eiioa?aioe?? “?aaa?e?oaoe?y oai?eo
iioeeiai a?eo ?c caoai?thaaiiyie na?oeaai-noaeeiii? nenoaie ?
oea?aa?aeueiith noaeeiiith iaoieia??th” (Ee?a, aeiaoaiue, 1997), XIV
c’?caeo oa?aiaao?a Oe?a?ie (Ee?a, aa?anaiue, 1998), Ieaioio ea?ae?ieia?a
Oe?a?ie (Ee?a, eenoiiaae, 1998). Ai?iaaoe?y aeena?oaoe?? a?aeaoeany
17.06.98 ?. ia iaoeiai-i?aeoe/i?e eiioa?aioe?? a?aeae?eaiue ?aai?iaoe??
oa ?ioaineaii? oa?ai??, aino?iai ?ioa?eoo i?iea?aea oa
a?aeiiaethaaeueiiai e?eoaaiiy, a?eoi?e na?oey oa eaai?aoi???
aenia?eiaioaeueii? ea?ae?ieia?? Oe?a?inueeiai IAe? ea?ae?ieia?? ?i.
aeaae. I.Ae. No?aaeanea IIC Oe?a?ie.

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 7 ae?oeiaaieo
i?aoeue.

No?oeoo?a aeena?oaoe??. Iiaiee ianya aeena?oaoe?? — 149 noi??iie.
Aeena?oaoe?y neeaaea?oueny ?c anooio, iaeyaeo e?oa?aoo?e, 7 aeaa aeanieo
aeine?aeaeaiue, caeeth/aiiy, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e oa
nieneo e?oa?aoo?e. ?ethno?iaaia 8 iaethieaie oa 35 oaaeeoeyie. Nienie
e?oa?aoo?e i?noeoue 200 aeaea?ae, c ieo 29 ee?eeeoeath.

INIIAIEE CI?NO ?IAIOE

?iaioa aaco?oueny ia ianoaaeaii? 100 oai?eo, ui aoee aini?oae?ciaai? a
Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo ea?ae?ieia?? c ae?aaiicii A?I,
yeee aoa anoaiiaeaiee a?aeiia?aeii aei ?aeiiaiaeaoe?e aenia?o?a AIC
(1971) ia iniia? iayaiino? ee?i?/ieo, a?io?i?/ieo oa
aeaeo?iea?ae?ia?ao?/ieo e?eoa???a.

A ianoaaeaiiy ia aeeth/aeeny oai?? c iaaeinoaoi?noth e?iaiia?ao IIA-O
no., ii?ooaiiyie aioo??oiueioeoii/eiai? oa ao??iaaio?eeoey?ii?
i?iaiaeeiino?, a?ia?oii?/iith oai?iaith O no., caoai?thaaiiyie
iii?ii-?ooiaiai aia?aoo, aeaeiiiainiaaieie noiooi?ie caoai?thaaiiyie.

A aeaiiio aeine?aeaeaii? i?ae ?IN ?icoi?ee a?aeiiaeaiiy aia?iiciiai
aieth i?ney ?icaeoeo A?I a ia??iae a?ae 24 aiae aei 4 oeaei?a.

Aoei ianoaaeaii 100 oai?eo (/ieia?e?a) A?I a?eii a?ae 36 aei 65 ?ie?a
(na?aaei?e a?e 49,4 + 1,6 ?ie?a), aini?oae?ciaaieo o ia??iae a?ae 1 aei
72 aiaeei (a na?aaeiueiio /a?ac 15,9 + 2,3 aiae) i?ney ?icaeoeo
iaea?eueo ?ioaineaiiai aia?iiciiai i?enooio. A ia?oo aeiao caoai?thaaiiy
aoei aini?oae?ciaaii 86 (86%) oai?eo a na?aaeiueiio /a?ac 7,4 + 0,8
aiaeei a?ae ii/aoeo aieueiaiai neiae?iio. Ia i?aenoaa? ee?i?/ieo
i?iya?a, aeaeo?iea?ae?ia?ao?/ieo iciae oa a?io?i?/ieo oano?a o 90 oai?eo
aoa ae?aaiinoiaaiee e?oiiiaiaieuaaee A?I (o 62 c ieo — o?ainio?aeueiee).
Aino?ee ?ioa?eo i?iea?aea aoa ia?aeiiith iai?oanoaoe??th ?oai?/ii?
oai?iae na?oey (?ON) o 64 (64%) oai?eo. ?aiiy iino?ioa?eoia noaiiea?ae?y
aeieeaea ia 1 — 21 aeaiue (a na?aaeiueiio ia 6,1 + 1,4 aeaiue) i?ney
?icaeoeo A?I.

I?ney aini?oae?caoe?? oa anoaiiaeaiiy ae?aaiico A?I oai?ei i?ecia/aeeny
o?iiaie?oe/i? i?aia?aoe, aetheici-?inoe?ii-eae??aa noi?o, aiaeueaaoeee,
aaoa-aae?aiiaeieaoi?e, i?o?aoe i?ieiiaiaaii? ae??, aioe-eiaaoeyioe,
?ia?a?oi?e aia?ioaiceiia?aoai?thth/iai oa?iaioo.

Aeey ?ica’ycaiiy iinoaaeaieo caaaeaiue oai?ei aoei i?iaaaeaia eiiieaenia
ianoaaeaiiy, yea aeeth/aei e??i ?aoaeueiiai aiae?co ee?i?/iiai ia?aa?ao
caoai?thaaiiy i?iaaaeaiiy AAI (aaeia?aiiao??y), AoiEA
(aoiea?ae?ia?ao?y), OI (oieoa??anueea iii?oi?oaaiiy), EAA
(ei?iia?i-aia?ia?ao?y), aeine?aeaeaiiy aeayeeo iieaciee?a a?ieia?/ii
aeoeaieo nenoai. Ianoaaeaiiy i?iaiaeeeenue a aeeiai?oe? ia 3-4-io oeaei?
A?I oa /a?ac 3-4 i?n (AAI, AoiEA oa OI).

Aeey ioe?iee iniiaieo ia?aiao??a aaiiaeeiai?ee i?iaiaeeee AoiEA ia
aia?ao? «YEN-O-01I» (Eeoaa). ?a?no?oaaee 2-eaia?i? iiceoe?? na?oey. Ia
iniia? oi?ioe, ui caeeaaeai? a eiii’thoa?, a iiiaio ianoaaeaiiy
ioe?ithaaee caaaeueii i?eeiyo? ia?aiao?e AoiEA — OA (o?aeoe?y aeeeaeo),
EAeI (e?ioeaai- ae?anoie?/iee ia’?i), ENI (e?ioeaai-nenoie?/iee ia’?i),
a oaeiae oiaueio no?iie e?aiai oeoii/ea a ae?anoieo (caaeiuei? no?iee
oa i?aeoeoii/eiai? ia?aoeiee).

Aeey i?iaaaeaiiy 24-aiaeeiiiai OI aeei?enoiaoaaee aeaieaiaeuei?
?aei?aea?e c ?a?no?aoe??th aeaeo?iae?a, ye? a?aeiia?aeaee oi/eai V2 oa
V5 noaiaea?oii? aeaeo?iea?ae?ia?ao?? (AEA). Eiii’thoa?iee aiae?c
io?eiaieo caien?a i?iaiaeeany ia aia?aoao o??i «Kitmed» (NOA-Oai?ueia)
oa «Custo» (I?ia//eia).

Aaaeaiiy iaoe??ioaie uiaeaiiee?a naiiii/oooy a aeaiue i?iaaaeaiiy OI, a
yeeo ?a?no?oaaee ?icaeoie aia?iicieo i?enooi?a, aeicaieeei ioe?ieoe
ia?aiao?e OI ie?aii aeey aieueiai? oa aacaieueiai? ?oai?? i?iea?aea (A?I
oa AA?I).

I?i caeeoeiao i?aoeacaeaoi?noue noaeeee ca ?acoeueoaoai AAI, yeo
cae?enithaaee ca caaaeueiii?eeiyoith iaoiaeeeith ii iaia?a?ai?e
noiaeoea-c?inoath/?e noai?, ii/eiath/e c iiooaeiino? 25 Ao, ia oii?
canoinoaaiiy aioe?oai?/ii? oa?ai?? ia aaeia?aiiao?? «AA-02» c caienii
AEA ia 6-eaiaeueiiio naiiienoe? «Bioset» (I?ia//eia) a 12 noaiaea?oieo
a?aeaaaeaiiyo.

*anoei? iaoe??io?a aoea i?iaaaeaia EAA ca iaoiaeii M.Judkins (1967). A
ia?o? aiaeeie A?I aeine?aeaeaiiy aeeiioaaeenue ni?a?ia?oieeaie
a?aeae?eaiiy ?aioaaiaiaeiaaneoey?ii? o??o?a?? (ea?. — i?io.
TH.I.Nieieia) ia aia?ia?ao?/i?e onoaiiaoe? «Angioscop-C» o??ie «Siemens»
(Aa?iai?y), /a?ac 1-1,5 i?n. — ni?a?ia?oieeaie IAe? NNO (ea?.- i?io.
A.?.O?noeaiei). Ioe?ithaaee noai e?ai? ei?iia?ii? a?oa??? (EA) , i?aai?
EA, ia?aaeiuei? ieco?aeii? EA, ae?aaiiaeueii? oa iaeiath/i? EA.
Aaiiaeeiai?/ii aaaiieie aaaaeaeenue noaiice i?e caoaeaii? EA a?eueo
i?ae ia 75%.

A a?aeae?eaii? iiaeo iaoiae?a aeeaaiinoeee oa aeine?aeaeaiue (ea?.-
i?io. E.A.Noaaeithe) i?iaiaeeee ioe?ieo ie?aieo iieaciee?a
iae?iaoii?aeueii? eaiee.

Iaoaiaoe/io ia?iaeo ?acoeueoao?a aeine?aeaeaiue cae?enithaaee ia IAII
oeia IBM c aeei?enoaiiyi nenoai cai?o aac aeaieo “Dbase” oa “FoxPro”
oa i?ia?ai ii??aiyiiy na?aaei?o aaee/ei, na?aaeiueieaaae?aoe/ieo
a?aeoeeaiue, ioe?iee t-e?eoa??th No’thaeaioa.

Ia ia?oiio aoai? aeine?aeaeaiiy aoee aeae?eai? oai?? c ?IN (48 oai?eo)
oa 52 oai?eo, o yeeo noaiiea?ae?y i?ney ?icaeoeo A?I aoea a?aenooiueith.

Oai?? c ?IN oa a?oia ni?anoaaeaiiy i?aeoe/ii ia a?ae??ciyeenue ca
a?eii, eieae?caoe??th ?I oa no?ieai aini?oae?caoe?? (i?e ?IN oai??
aini?oae?coaaeenue ia 6,5 aiae i?ci?oa, aea oey a?aei?ii?noue ia aoea
a??ia?aeiith). A oie naiee /an a a?oi? c ?IN /ano?oa niinoa??aaee
?icaeoie ae??aiiaiaieuaaiai o?aaeaiiy (14,6%) a ii??aiyii? c a?oiith
eiio?ieth (5,8%), iiaoi?ieo ?I (37,2% oa 3,9%, a?aeiia?aeii) oa
iayaiino? a?ia?oii?/ia oai?iaa (AO) a aiaiiac? (45,8% oa 23,1%).
?oai?/ia oai?iaa na?oey aoea ae?aaiinoiaaia aei ?icaeoeo ?I o 31 (64,6%)
oai?iai c ?IN oa o 5 (9,7%) — a?oie ni?anoaaeaiiy. O 15 (31,2%)
iaoe??io?a c ?IN oa o 12 (23,1%) a?oie ni?anoaaeaiiy ?I ?icaeaaany
i?ney ia??iaeo ianoaa?eueii? noaiiea?ae??.

A iiaeaeueoiio ia iniia? ?aoaeueiiai aea/aiiy aiaiianoe/ieo aeaieo
aeyaeeinue aeioe?eueiei ?icae?eeoe oai?eo c ?IN ia aea? a?oie: 1-o c
yeeo neeaee 26 oai?eo, o yeeo ?ioa?eoo ia?aaeoaaea noaiiea?ae?y o
aeaeyae? noaa?eueii? oi?ie, 2-o — 22 iaoe??ioa, o yeeo ia 4-15 aeaiue
i?ney ?icaeoeo A?I aeieeea ?IN. O?aoy a?oia i?aaenoaaeaia 52 oai?eie c
iaoneeaaeiaiei ia?aa?aii ?I. Oa?aeoa?enoeea oai?eo o?ueio a?oi
iiaeaia a oaaeeoe? 1.

Oaaeeoey 1

Ee?i?/ia oa?aeoa?enoeea oai?eo

Iieacieea?oia 1

(n = 26)a?oia 2

(n = 22)a?oia 3

(n = 52)A?e (?iee)49,9 + 2,348,1 + 2,048,6 + 1,5No?iee
aini?oae?caoe??23,5 + 5,716,1 + 4,2 11,9 + 2,8Eieae?caoe?y ?I:

— ia?aaei?e

14 (53,8%)

14 (63,6%)

26 (50,0 %)- caaei?e11 (42,3%)8 (36,4%)25 (48,1%)oee?eoey?iee1
(3,9%)—1 (1,9%)Aaee/eia ?I:- o?ainio?aeueiee12 (46,2%)16 (72,7%)34
(65,4%)e?oiiiaiaieuaaee8 (30,8%)5 (22,7%)15 (28,8%)- ae??aiiaiaieuaaee6
(23,1%)1 (4,5%)3 (5,8%)E?aoi?noue ?I:- ia?aeiiee15 (57,7%)18 (81,8%)50
(96,1%)- iiaoi?iee11 (42,3%)4 (18,2%)2 (3,9%)AO13 (50,0%)9 (40,9%)12
(23,1%)

A 2 a?oi? iaeaea aaea?/? /ano?oa ?ioa?eo i?iea?aea (?I) eieae?coaaany a
ia?aaeiuei-naioaeueii-aa?o?aeia?e iaeano? e?aiai oeoii/ea, a oie /an
ye o iaoe??io?a 1 oa 3 a?oi oey ia?aaaaa aoea iacia/iith.

A 1 a?oi? o?ainio?aeueia oa e?oiiiaiaieuaaa aaee/eia o?aaeaiiy
cono??/aeanue i?eaeecii c iaeiaeiaith /anoioith (46,2% oa 38,8%), oi
a 3 a?oi? oe? iieacieee neeaee 65,6% oa 28,8%, a?aeiia?aeii, oa aoee
iniaeeai cia/ieie o 2 a?oi? (72,7% oa 22,7%). Aiaeia?/ia ea?oeia
niinoa??aaeany i?e ioe?ioe? ?icaeoeo ae??aiiaiaieuaaeo ?I, ye?
iaea?eueo /anoi aeieeaee a 1 a?oi? (23,1%) o ii??aiyii? c 3 a?oiith
(5,8%) oa iniaeeai 2 (4,5%).

Nooo?aa a?aei?ii?noue a?aei?/aia o a?aeiioaii? ?icaeoeo iiaoi?ieo ?I a
??cieo a?oiao. Oae, a 1 a?oi? ?I aia?oa aoa ae?aaiinoiaaiee o 57,7%
oai?eo, iiaoi?iee ?I niinoa??aaany aeaui ??aeoa — o 42,3% iaoe??io?a.
A 2 a?oi? oey a?aei?ii?noue aeyaeeanue a?eueo cia/iith (81,8% oa 18,2%
oai?eo) oa iniaeeai ae?aaeaiith — a 3 a?oi? (96,1% oa 3,9% oai?eo).
A?ia?oii?/ia oai?iaa aeieeaea a 1 (58,8%) oa 2 (48,9%) a?oiao a?eueo
i?ae aaea?/? /ano?oa o ii??aiyii? c 3 (23,1%).

Iaie anoaiiaeaii, ui aei A?I ?ON aoea ae?aaiinoiaaia o an?o oai?eo 1
a?oie, o 5 (22,7%) – 2 a?oie oa o 5 (9,7%) – 3 a?oie. ?icaeoeo A?I
ia?aaeoaaea IN o 12 (46,2%) oai?eo 1 a?oie oa 12 (23,1%) – 3 a?oie. A
i?ioean? aeeiai?/iiai niinoa?aaeaiiy anoaiiaeaia oaiaeaioe?y aei
iie?auaiiy ee?i?/iiai ia?aa?ao caoai?thaaiiy: e?euee?noue iaiaae?a
noaiiea?ae?? ciaioeeanue o 10 (38,5%) oai?eo 1 a?oie oa o 12 (54,6%) – 2
a?oie; a oie naiee /an o 4 (15,3%) iaoe??io?a 1 a?oie oa o 3 (13.6%) 2
a?oie a?aei?/aeiny i?ia?anoaaiiy noaiiea?ae??, a o 4 (7,7%) oai?eo 3
a?oie – ?? ?icaeoie; o 2 (7,7%) oai?eo 1 a?oie ca?a?no?iaai? eaoaeuei?
aeiaaeee.

I?e aea/aii? iniaeeainoae, ui aeaoa?i?iothoue aaiiaeeiai?eo o oai?eo
?IN, ia aoei aeyaeaii a?aei?iiinoae o o?ueio a?oiao o a?aeiioaii? EAeI,
ENI oa OA.

Oae, EAeI a 1 a?oi? neeaaeaa 177,5 + 9,0 ie, o 2 — 179,6 + 7,7 ie,
o 3 — 164,4 + 3,9 ie, ENI — 96,6 + 6,7 ie, 97,9 + 5,7 ie oa 90,1
+ 2,4 ie, a?aeiia?aeii, OA — 46,3 + 1,7%, 45,1 + 1,7% oa 46,1 +
1,2%. Oaeiae ia aoei anoaiiaeaii a??ia?aeieo a?aei?iiinoae i?ae a?oiaie
o a?aeiioaii? oaeeo iieaciee?a ye oiaueia i?aeoeoii/eiai? ia?aoeiee, ui
neeaaeaea 1,10 + 0,06 ni o oai?eo 1 a?oie, 1,00 + 0,05 ni 2 a?oie oa
1,10 + 0,04 ni — 3 a?oie, oa oiaueia caaeiuei? no?iee e?aiai oeoii/ea,
yea neeaaeaea 0,99 + 0,06 ni, 1,00 + 0,05 ni oa 1,00 + 0,03 ni.

Aiae?c oa?aeoa?o e?iaco aeicaieea anoaiiaeoe, ui a 1 a?oi? ii?iie?iac
a?coae?coaaany o 5 (19,2%) oai?eo (ui, iiaeeeai, iiynith?oueny
/anoei ?ic-aeoeii ae??aiiaiaieuaaeo ?ioa?eo?a), o 2 a?oi? — ia
niinoa??aaany, a 3 — o 1 (1,9%) oai?iai; a?iie?iac — o 14 (53,9%), o
15 (68,2%) oa o 36 (69,2%), a?aeiia?aeii, ae?iac — o 3 (11,5%), 3
(13,6%) oa o 3 (5,8%) oai?eo, ae?ne?iac — o 4 (15,4%), o 4 (18,2%) oa o
12 (23,12%) oai?eo. Oaeei /eiii, i?e ia?oiio ianoaaeaii? iaea?eueo
caa?aaeai? ciie i?iea?aeo a?coae?coaaeeny a 1 a?oi?: o?eueee o 26,9%
oai?eo cao?eniaai? ae?eyiee a- oa ae?ne?iaco. O 2 a?oi? oe? ciie
neeaaeaee 31,8%, a 3 – 28,9%. I?e oeueiio ae?eyiee ii?iie?iaco a 1 a?oi?
niinoa??aaee o 5 (19,2%) iaoe??io?a, a 3 a?oi? – o?eueee o 1 (1,9%), a 2
– acaaae? ia a?coae?coaaeeny.

I?e iiaoi?iiio aeine?aeaeaii? /a?ac 3 i?n a 1 a?oi? a?aei?/aeiny
cieaeaiiy ia’?iieo iieaciee?a (EAeI aei 164,5 + 9,1 ie, ENI – 86,7 + 6,7
ie), aea aiane?aeie aaeeeiai ?iceeaeo oeeo aaee/ei ci?ie iineee oa?aeoa?
oaiaeaioe?? (p>0,05), OA neeaaeaea 47,6 + 1,8%. O 2-e a?oi? a?aeaoaaeiny
ca?eueoaiiy EAeI aei 189,5 + 8,0 ie, ??no OA aoa iaa??ia?aeiei (48,3 +
1,8%). A 3 a?oi? – ca?a?no?iaai? iaeaea oae? ae aeai?, ye ? i?e ia?oiio
ianoaaeaii? (EAeI – 169,8 + 4,8 ie, ENI – 90,3 + 3,5 ie, OA – 46,6 +
0,9%). Aeeiai?ee oiaueie no?iie ia niinoa??aaeiny a aeiaei?e a?oi?.
Iaiao?aeii i?aee?aneeoe, ui i?e iiaoi?iiio ianoaaeaii? iaea?eueo
iaaeaaii?e?iia aeeiai?ea aoiea?ae?ia?ao?/ieo iieaciee?a niinoa??aaeany a
2 a?oi?, o oai?eo yei? a?aeaoaaeiny ca?eueoaiiy EAeI, a oie /an ye a 1
a?oi? niinoa??aaee iioei?caoe?th aaiiaeeiai?ee c? cieaeaiiyi ia’?iieo
iieaciee?a, a 3 a?oi? cia/ii? aeeiai?ee ia aoei. I?e aea/aii? cii
ii?ooaiiy nei?ioeeaino? aoei iieacaii, ui a 1 a?oi? nei?ioeea?noue ia
aoea ii?ooaia o 9 (34,7%) oai?eo, o 2 a?oi? – o 3 (13,6%), a 3 a?oi? —
o 8 (15,4%) oai?eo. A?iie?iac a?coae?coaaany o 11 (42,3%) iaoe??io?a 1
a?oie, 12 (54,5%) — 2 a?oie oa o 31 (59,7%) — 3 a?oie. Ae?iac aoa
ca?a?no?iaaiee o 3 (11,5%) oai?eo 1 a?oie, o 4 (18,2%) — 2 a?oie oa o 2
(3,8%) iaoe??io?a 3 a?oie. Ae?ne?iac ciaeaeaii o 3 (11,5%) oai?eo 1
a?oie, 4 (18,2%) — 2 a?oie oa o 11 (21,2%) — 3 a?oie. A oiae? iiaoi?iiai
ianoaaeaiiy a on?o o?ueio a?oiao niinoa??aaeiny iie?auaiiy
nei?ioeeaino? ia?aaaaeii ca ?aooiie a?iie?iaoe/ieo ae?eyiie. A
aeeiai?oe? e 3-io i?nyoeth ii?ii- oa a?iie?iac a?coae?coaaany o 20
(77,0%) oai?eo 1 a?oie, o 15 (68,1%) – 2 a?oie oa o 39 (75,1%)
iaoe??io?a 3 a?oie.

A?aenooi?noue a??ia?aeieo a?aei?iiinoae aaiiaeeiai?/ieo ia?aiao??a a
a?oiao i?e ia?aeiiiio ianoaaeaii? iaoiiaeaia iaaiith ee?i?/iith
iaiaeii??aei?noth ii??aithaaeueieo a?oi, yea iieyaaei a cia/ii
/ano?oiio aeieeiaii? ae??aiiaiaieuaaeo oa iiaoi?ieo ?I o oai?eo 1 a?oie.
I?e ?icaeoeo ae??aiiaiaieuaaiai o?aaeaiiy eieeaaiiy ia’?iieo iieaciee?a
caeeoaeenue a iaaeao ii?iaeueieo cia/aiue. C o?aooaaiiyi ia?aaaaeiiai
?icaeoeo ae??aiiaiaieuaaeo ?I a 1 a?oi? (23,1%) o ii??aiyii? c ?ioeie,
naia oeei oaeoii iiynith?oueny iaeiioeii?noue aeaieo c a?oiith
eiio?ieth. I?aeoaa?aeaeaiiyi oeueiio ? cia/ia ca?eueoaiiy EAeI oa ENI o
iaoe??io?a ?IN o ii??aiyii? c 3 a?oiith i?e aiae?c? o?eueee
e?oiiiaiaieuaaeo (a oiio /ene? o?ainio?aeueieo) ?I.

Oaeei /eiii, ia i?aenoaa? aea/aiiy aaiiaeeiai?/ieo iieaciee?a
anoaiiaeaii, ui iaea?eueo iaaeaaii?e?iia aeeiai?ea aecia/aeany o oai?eo
?IN o 2 a?oi?. Iieacieee o iaoe??io?a 1 a?oie i?aeoe/ii ia a?ae??ciyeeny
a?ae a?oie eiio?ieth, ui iaoiiaeaii c iaeiiai aieo /anoei ?icaeoeii a 1
a?oi? ae??aiiaiaieuaaeo ?I, c ?ioiai aieo – noaiii “i?a?ea/aoi? ?oai??”,
yeee ia?aaeoaaa ?I, a oaeiae /anoei ?icaeoeii a?ia?o?io?? e?aiai
oeoii/ea (EO) a 1 a?oi? o ii??aiyii? c 2 a?oiith, yea iaea eiiiainaoi?ia
cia/aiiy aeey caa?aaeaiiy nenoie?/ii? ooieoe??, ui iniaeeai i?iyaeyeiny
a aeeiai?oe? i?e iiaoi?iiio ianoaaeaii?. A 3 a?oi? o iaoe??io?a i?ney
ieanoeee aei 3-ai i?nyoeth niinoa??aaeany iaioa aeeeaoaoe?y.

Io?eiai? ?acoeueoaoe na?ae/aoue i?i iaaeaaii?e?iiee aaiiaeeiai?/iee oii
o iaoe??io?a 2 a?oie oa iaaeinoaoith aoaeoeai?noue canoiniaaieo
oa?aiaaoe/ieo oa ?ioa?aaioe?eieo ao?o/aiue, ui aeeeoo? iaiao?aei?noue
iiooeo a?eueo ?ioi?iaoeaieo ia?ea??a aaiiaeeiai?ee oa a?eueo aaeaeaaoieo
iaoiae?a e?eoaaiiy.

A iaoiio aeine?aeaeaii? OI aoei i?iaaaeaia o 53 oai?eo: 16 (61,5%)
iaoe??io?a 1 a?oi?, 13 (59,1%) – 2 a?oie oa 24 (46,2%) iaoe??io?a 3
a?oie. ?oai?y i?iea?aeo ca ia??iae iii?oi?oaaiiy ia aoea ca?a?no?iaaia o
6 (37,5%) oai?eo 1 a?oie, 2 (15,4%) – 2 a?oie oa o 14 (58,3%) oai?eo 3
a?oie. Caaaeueia i?iea?ae?aeueia ?oai?y (I?) o?eaae?noth a?eueoa 60 oa
niinoa??aaeanue o 4 (40,0%) oai?eo 1 a?oie, o 2 (18,2%) 2 a?oie oa o 2
(20,0%) – 3 a?oie. A 1 a?oi? i?iea?ae?aeueia ?oai?y o aeaeyae? A?I, AA?I
oa ?o eiia?iaoe?? anoaiiaeaia c iaeiaeiaith /anoioith, a?aeiia?aeii o 3
(30%), o 4 (40,0%) oa o 3 (30,0%) oai?eo. O 2 a?oi? /ano?oa aeieeaea
?cieueiaaia ?oai?y: A?I aoea ca?a?no?iaaia o 4 (36,7%), AA?I — o 5
(45,4%) iaoe??io?a oa o?eueee o 2 (18,3%) oai?eo a?aei?/aeany
eiia?iaoe?y A?I oa AA?I. Aieiai? iieacieee OI iaaaaeai? o oaaeeoe? 2.

?acoeueoaoe OI aeicaieeee anoaiiaeoe iaea?eueo cia/io I? o iaoe??io?a 1
a?oie, a iaio?e i??? – 2 a?oie, i?e/iio ci?ie i?e ?icaeoeo A?I aoee
a?eueo cia/oueie o ii??aiyii? c AA?I. E??i oiai, o 41,7% oai?eo 3 a?oie
aoea ca?a?no?iaaia I? o aeaeyae? AA?I.

O oai?eo c ?IN (1 oa 2 a?oie) a?ey 25-30% I? i?eoiaeeeiny ia i?/i?
aiaeeie (0-6 aiae), i?e oeueiio a 1 a?oi? aianie A?I neeaaeaa 32,1%, a
AA?I – 20,7%, a oie /an ye o 2 a?oi? o i?/i? aiaeeie /ano?oa
?a?no?oaaeany AA?I (55,7%) o ii??aiyii? c A?I (6,8%). A 3 a?oi? ia
niinoa??aaeiny aeiaeiiai ai?ciaeo ?oai?? a oeae aiaeeiiee ?ioa?aae.

Oaaeeoey 2

Iniiai? iieacieee OI o oai?eo c ?IN oa a?oie eiio?ieth

Iieacieee1 a?oia2 a?oia3 a?oian A?I (ai/aeia.)2,2 + 0,041,3 + 0,2*—t
A?I (oa)42,7 + 8,131,5 + 9,9—st A?I (ii)1,7 + 0,391,1 + 0,08—n
AA?I(ai/aeia.)2,0 + 0,691,3 + 0,21,60 + 0,34t AA?I (oa)35,2 + 5,515,2 +
3,0*20,4 + 5,7***st AA?I (ii)1,5 + 0,291,2 + 0,111,31 + 0,12n I?
(ai./aeia.)2,7 + 0,671,5 + 0,211,60 + 0,34t I? (oa)50,3 + 8,127,3 +
7,820,4 + 5,7**st I? (ii)1,60 + 0,281,13 + 0,071,31 + 0,12I?ei?oea. * —
? 1-2 < 0,05; ** - P 1-3 < 0,01; *** - P 1-3 < 0,04 I?e aiae?c? ?acoeueoao?a OI /a?ac 3 i?n i?ney A?I iaea?eueo cia/ieie aoee ii?ooaiiy o 2 a?oi?, a ye?e /anoioa oa o?eaae?noue A?I oa AA?I ia?aaeuoaaee oe? iieacieee a 1 a?oi?, a oaeiae on? iieacieee a 3 a?oi?. A oie naiee /an aeai?an?y naaiaioo ST aoea aeeaoith a 1 a?oi? o ii??aiyii? c 2. I?e ni?anoaaeaii? ?acoeueoao?a OI c aeaieie 1-ai ianoaaeaiiy o oai?eo 1 a?oie a?aei?/aeiny ciaioaiiy /anoioe oa o?eaaeino? A?I i?e iaaiiio (oi/a ? iaa??ia?aeiiio) iiaeeaeaii? aeai?an?? naaiaioo ST. Ui noino?oueny iieaciee?a, ye? oa?aeoa?ecothoue AA?I, oi a ia?o?e a?oi? aiie i?aeoe/ii ia a?ae??ciyeenue ca aeiyoeii iieacieea ci?uaiiy naaiaioo ST, yeee ca?eueoeany i?e iiaoi?iiio ianoaaeaii?. O 2 a?oi? i?e iiaoi?iiio ianoaaeaii? o ii??aiyii? c 1-i /ano?oa aeieeaee ai?ciaee A?I, a oaeiae ca?eueoeeenue an? iieacieee, ui oa?aeoa?ecothoue AA?I. A 3 a?oi? i?enooie AA?I noaee ??aeoeie, oi/a ?o o?eaae?noue eeoeeany oaeith naiith (oaaeeoey3). Oaaeeoey 3 Iieacieee OI o oai?eo c ?IN oa a?oie eiio?ieth a aeeiai?oe? Iieacieee1 a?oia2 a?oia3 a?oian A?I (ai/aeia.)1,7 + 0,673,5 + 0,5---t A?I (oa)23,0 + 9,936,0 + 9,0---st A?I (ii)1,97 + 0,961,0 + 0,1---n AA?I(ai/aeia.)2,0 + 1,03,5 + 1,81,00 + 0,12t AA?I (oa)31,2 + 8,147,8 + 2,722,5 + 4,5st AA?I (ii)1,78 + 0,281,41 + 0,281,10 + 0,10 Oaeei /eiii, oai?? 3-? a?oie i?e a?aenooiino? ee?i?/ii? neiioiiaoeee o aeaeyae? ?IN, aea i?e iayaiino? AA?I i?e OI iiaeooue aooe a?aeianai? o a?oie i?aeaeuaiiai ?eceeo, ui i?aeoaa?aeaeo?oueny cieaeaiiyi aeeiiaii? ?iaioe i?e AAI oa ca?eueoaieie ii?iaeieiaie e?aiai oeoii/ea, i?e/iio ia o?eueee a noaoe?iia?iiio ia??iae?, aea e c iiaeaeueoei ca?eueoaiiyi EAeI oa ENI /a?ac 3 i?n i?ney A?I. O?eaaea iii?oi?oaaiiy AEA ca iaoiaeii Oieoa?a aea? iiaeeea?noue anoaiiaeoe ua iaeio oa?aeoa?io aeey ?IN ?eno, yea iieyaa? a iayaiino? o oeeo oai?eo /anoeo ai?ciae?a AA?I. I?e ii??aiyii? ?acoeueoao?a OI oai?eo c ?IN oa a?oie eiio?ieth anoaiiaeaii, ui /anoioa oa o?eaae?noue AA?I o iaio a?oiao i?eaeecii iaeiaeiaa, aea aeai?an?y naaiaioo ST i?e ?IN aeeaoa, i?ae a a?oi? ii??aiyiiy, a o?eaae?noue A?I aeiaoa ca AA?I. I?e aea/aii? oee?eaaeiino? anoaiiaeaii, ui a 1 a?oi? i?e I? a?aeiia?aeaa ii/aoeo o?ce/ii? aeoeaiino? oa niinoa??aaany a ia??iae 6-12 aiae. ?oai?y o 2 a?oi? ?a?no?oaaeany ??aiii??ii i?ioyaii aeiae. O 3 a?oi? i?e ?oai?? a?aeiia?aeaa iaeneioio o?ce/ii? aeoeaiino? (12-18 aiae). E??i oiai anoaiiaeaii, ui o iaoe??io?a c ?IN 25-30% I? ?a?no?o?oueny o i?/i? aiaeeie (0-6 aiae), i?e oeueiio a 2 a?oi? o oeae aiaeeiiee ?ioa?aae a?aei?/aeiny 55,7% AA?I. Aeeiai?/iee eiio?ieue iieacaa, ui /a?ac 3 i?n a 1 a?oi? a?aeaoaaeiny ciaioaiiy o?eaaeino? A?I. Ca?eueoaiiy na?aaeiueiai /ano i?iea?ae?aeueii? ?oai?? o oai?eo 2 a?oie aoei iaoiiaeaii ??ceei iia??oaiiyi iieaciee?a OI o 3 oai?eo, o yeeo eieeaaiiy aeiaiai? ?oai?? i?iea?aeo aoee a?ae 87 aei 184 oa, ui a?aeiia?aeaei iia??oaiith ee?i?/iiai ia?aa?ao. Ii?yae c oeei, o 70,0% oai?eo 2 a?oie niinoa??aaeany iiceoeaia aeeiai?ea iieaciee?a OI. Ui noino?oueny noaio aeoii?/ii? aeoeaiino?, oi i?e 1-io ianoaaeaii? niinoa??aaeiny ca?eueoaiiy oeoii/eiai? aeno?anenoie?? a?ae 1-? aei 3-? a?oie, a oie /an ye i?e iiaoi?iiio ianoaaeaii? o 2-e a?oi? a?aeaoaaeiny ia?inoaiiy aeno?anenoie??, a a 3- cieaeaiiy. Aaeia?aiiao??y i?iaiaeeeanue a?eueoino? oai?eo o an?o a?oiao (a?ae 81,2% aei 92%). Ca ea?ae?aeueieie i?e/eiaie AAI ia i?iaiaeeee o 15% oai?eo 1 a?oie, 18,8% - 2 a?oie oa o 7% - 3 a?oie. Aiae?c ?acoeueoao?a caeeoeiai? i?aoeacaeaoiino? iieacaa, ui o iaoe??io?a c ?IN o ii??aiyii? c a?oiith eiio?ieth a?aei?/aeeny a?eueo iecuee? cia/aiiy aeeiiaii? ?iaioe, ii?iaiaeo aaee/ei iiooaeiino?, ioeueno, “iiaea?eiiai aeiaooeo”. O?eaae?noue i?iae a 1 a?oi? neeaaeaea 9,0 + 1,06 oa, o 2 – 8,88 + 0,43 oa, o 3 - 11,54 + 0,72 oa (P2-3<0,05). Aeaa?aoe?? naaiaioo ST ?a?no?oaaee a na?aaeiueiio o 2,60 + 0,40 a?aeaaaeaiiyo 1 a?oie, o 2,57 + 0.37 – 2 a?oie oa o 2,5 +0.33 a?aeaaaeaiiyo 3 a?oie. Na?aaeiy aeeaeia aeai?an?? naaiaioo ST noaiiaeea a?aeiia?aeii 1,59 + 0,50 ii, 1,33 + 0,33 ii oa 1,38 + 0,23 ii . Aieiai? iieacieee AAI iaaaaeai? o oaaeeoe? 4. Oaaeeoey 4 Iniiai? iieacieee AAI o oai?eo A?I IieacieeeA?oia 1 n=20 A?oia 2 n=16A?oia 3 n=43A (eAi)2235 + 4062062 + 345 *3202 + 314W (Ao) 45,2 + 5,1 *46,9 + 4,5 *60,5 + 3,6*NN ii/.70,0 + 3,267,6 + 3,272,2 + 1,9*NN ii?.85,8 + 3,882,8 + 4,3 *93,1 + 2,3AO ii/. 124,7 + 3,6120,0 + 2,9120,5 + 2,2AO ii?.150,3 + 6,1141,4 + 4,6 *154,0 + 3,6IAe ii/.86,8 + 4,680,9 + 4,186,5 + 2,5IAe ii?.130,7 + 8,9117,7 + 8,1 *145,4 + 5,8IAe43,9 + 7,736,3 + 5,859,3 + 4,7IAe/A2,53 + 0,352,64 + 0,682,63 + 0,33I?ei?oea. * - ?<0,05 a ii??aiyii? c 3-e a?oiith. Iecueea oiea?aioi?noue (25 Ao) aei o?ce/iiai iaaaioaaeaiiy ca?a?no-?iaaia o 7 (35,0%) oai?eo 1 a?oie, 5 (31,2%) - 2 a?oie oa o 7 (16,9%) – 3 a?oie; na?aaeiy oiea?aioi?noue (50 Ao) – 9 (45,0%) iaoe??io?a 1 a?oie., 8 (50,0%) – 2 a?oie oa 17 (39,6%) – 3 a?oie. Aeniea oiea?aioi?noue (75 Ao oa aeua) – niinoa??aaeanue, a?aeiia?aeii, o 4 (20,0%), 3 (18,8%) oa 18 (41,8%) oai?eo. Aiae?c i?e/ei i?eieiaiiy AAI iieacaa, ui ?icaeoie aieth naiino?eii /e a ii?aeiaii? c caaeeoeith, a?eoi??th /e ci?iaie ia AEA /ano?oa niinoa??aaany a 1 a?oi?, a oie /an ye I? o aeaeyae? aeaa?aoe?e naaiaioo ST, ci?i coaoey O /e eiiieaeno QRS /ano?oa ?a?no?oaaeany o 2 a?oi?. Ci?ie AEA noaee i?e/eiith i?eieiaiiy AAI o 30% iaoe??io?a 1 a?oie, 50% - 2 a?oie oa 41,8% - 3 a?oie. Ii??aiyiiy ?acoeueoao?a AAI o oai?eo a?oie eiio?ieth, o yeeo i?ae/an OI ca?a?no?iaaia AA?I, anoaiiaeei a?eueo iecueeee ??aaiue aeeiiaii? ?iaioe, i?ae o iaoe??io?a c ?ioaeoieie ?acoeueoaoaie OI. Ni?anoaaeaiiy aeaieo AAI oa AoiEA ia aeicaieeei anoaiiaeoe caeaaeiino? i?ae iieacieeaie AAI oa ci?iaie ia’?i?a e?aiai oeoii/ea, a oie naiee /an a?aei?/aia ei?aeyoe?y i?ae ??aiai aeeiiaii? ?iaioe oa aaee/eiith OA ( a a?oiao c OA<40% oa OA>39%).

Aiae?c ?acoeueoao?a AAI a aeeiai?oe? /a?ac 3 i?n i?ney A?I iieacaa
ca?eueoaiiy oiea?aioiino? aei aeiciaaiiai o?ce/iiai iaaaioaaeaiiy o 2
a?oi?, a 3 a?oi? iie?auaiiy iieaciee?a iineei oa?aeoa? oaiaeaioe??, a 1
a?oi? a?aei?/aeiny ca?eueoaiiy e?eueeino? oai?eo, ui aeeiiaee na?aaei?e
??aaiue iaaaioaaeaiiy (83,3%). Ii?iaiao iiooaei?noue 75 Ao oa aeua
aeeiiaee 50% oai?eo 2 a?oie oa 75% — 3 a?oie. Aea/aiiy aieeao
i?iaaaeaii? oa?ai?? aeaei iiaeeea?noue anoaiiaeoe aoaeoeai?noue
nenoaiiiai o?iiaie?c?no o iaoe??io?a 1 a?oie; eiai aoaeo o 2 oa 3
a?oiao ia a?aei?/aany.

Oaeei /eiii, o oai?eo c ?IN o ii??aiyii? c a?oiith eiio?ieth anoaiiaeaii
cieaeaiiy oiea?aioiino? aei iaaaioaaeaiiy a aino?iio ia??iae? c
oaiaeaioe??th aei ?? ca?eueoaiiy a aeeiai?oe? /a?ac 3 i?n. Anoaiiaeaia
caeaaei?noue i?ae ?acoeueoaoaie AAI oa aaee/eiaie OA, a oaeiae o
iaoe??io?a 3 a?oie i?ae aeaieie AAI oa ?a?no?aoe??th i?e OI AA?I.

Caiaeo ia i?iaaaeaiiy EAA aoei io?eiaii o 46 oai?eo. C ieo 14
iaoe??io?a a?aeiineeeny aei 1 a?oie, 6 – aei 2 oa 26 – aei 3 a?oie. Ia
aeeaey/enue ia a?aeiinii iaaaeeeo e?euee?noue oai?eo, ui aeyaeeeny a
eiaei?e a?oi?, ni?anoaaeaiiy ?acoeueoao?a EAA o oai?eo c ?IN ( 1 oa 2
a?oie) c a?oiith eiio?ieth ? oe?eeii ei?aeoiei. Ei?iia?iaia?ia?ao?y aoea
aeeiiaia o 20 (41,7%) oai?eo c ?IN oa o 26 (46,2%) — 3 a?oie.
?cieueiaaia o?aaeaiiy EA aoei a?coae?ciaaii o 8 (40,0%) iaoe??io?a c ?IN
oa o 18 (69,2%) – aac ?IN. Aaaaoinoaeeiia o?aaeaiiy aeyaeeiny o 9 (45%)
oai?eo c ?IN oa o 5 (19,2%) – aac ?IN. Noaiicoaaiiy noaeei aei 75%
a?aei?/aeiny o 3 (15,0%) iaoe??io?a c ?IN oa o 3 (11,5%) – aac ?IN. Ca
eieae?caoe??th noaiic?a anoaiiaeaii, ui i?e ?IN i?ieneiaeuei? a?aeae?ee
o?aaeaeeny o 2 (25,0%) iaoe??io?a, na?aaeiy o?aoeia noaeei – o 3
(37,5%), aeenoaeuei? a?aeae?ee – oaeiae o 3 (37,5%). O oai?eo aac ?IN
i?ieneiaeuei?, na?aaei? oa aeenoaeuei? a?aeae?ee aoee o?aaeai?,
a?aeiia?aeii o 8 (44,4%), o 6 (33,3%) oa o 4 (22,3%) oai?eo. ?cieueiaaia
o?aaeaiiy EA a?aei?/aeiny o 4 (28,6%) oai?eo 1 a?oie, o 4 c 6 oai?eo 2
a?oie oa o 18 (69,2%) iaoe??io?a 3 a?oie. A?aenooi?noue aaiiaeeiai?/ii
cia/ouiai noaiico (<75%) niinoa??aaeiny o 3 oai?eo 1 a?oie oa 3 – 3 a?oie. Eiia?iiaaia o?aaeaiiy EA a?aei?/aeiny o 7 (50%) iaoe??io?a 1 a?oie, o 2 (33,3%) oai?eo 2 a?oie oa o 5 (19,2%) – 3 a?oie. Ia i?aenoaa? ?acoeueoao?a EAA 27 oai?ei aoea i?iaaaeaia ia?eooaiia o?ainethi?iaeueia aia?iieanoeea oa 6 – ai?oiei?iia?ia ooiooaaiiy (ia 6-10 oeaei? A?I). Ooiooaaiiy (1-3 ooioe) aoee aeeiiai? o?eueee oai?ei 1 oa 2 a?oi (c ?IN). Aia?iieanoeeo cae?enieee 5 oai?ei 1 a?oie (o 3 aac?acoeue-oaoii), o 2 - 2 a?oie ( o 1 – iaaoaeoeaia), o 20 – 3 a?oie (o 14 – aoaeoeaia). Oaeei /eiii, a ?acoeueoao? i?iaaaeaiiai aeine?aeaeaiiy anoaiiaeaii, ui o iaoe??io?a c ?IN, a ia?oo /a?ao 1 a?oie o ii??aiyii? c a?oiith eiio?ieth, a?aei?/a?oueny aaaaoinoaeeiia o?aaeaiiy (45% i?ioe 19,2%). Ui noino?oueny nooiaiy ei?iia?inoaiico, oi ia ciaeaeaii nooo?aeo a?aei?iiinoae o ii??aiyeueieo a?oiao. O oie naiee /an o iaoe??io?a c ?IN ??aeoa o ii??aiyii? c a?oiith eiio?ieth a?aei?/aeiny i?ieneiaeueia o?aaeaiiy EA. Iniaeeaino? iae?iaoii?aeueii? ?aaoeyoe?? o oai?eo c ?IN oa?aeoa?ecoaaeeny i?aeaeuaiiyi aeoeaiino? ?ai?io, aeueaeinoa?iio, a?eueiee o??ienei-4, oeeee?/iee aaeaiiceiiiiioinoao oa cieaeaiiyi oeeee?/iee aoaiiceiiiiioinoao. Ine?eueee oeeee?/iee aaeaiiceiiiiioinoao noeioeth? ae?th eaoaoieai?i?a oa aacinianoe/ieo ai?iii?a, oi ii?ooaiiy aaeaino i?ae oeeee?/iee aaeaiiceiiiiioinoao oa oeeee?/iee aoaiiceiiiiioinoao iiaea aooe iaeiei c oaeoi??a ?icaeoeo ?IN. Iayai?noue ?IN c o?aooaaiiyi ciaeaeaieo iniaeeainoae iae?iaoii?aeueii? nenoaie, iio?aao? a?eueo “aa?aneaii?” oa?ai?? aeiiaoi?aie NO, aaoa-aae?aiiaeieaoi?aie oa aioaaii?noaie eaeueoe?th. Oaeei /eiii, o oiae? i?iaaaeaiiai aeine?aeaeaiiy aeae?eai? ee?i?/i? a?oie c ?IN, a yeeo aeinyaiaii aoaeo i?e eiina?aaoeaiiio e?eoaaii?, aeinoaoiueiio aeey a?aeiiaeaiiy i?aoeacaeaoiino? ia ??ai? eaaei? ?iaioe. Iaaeeeaiaioicia e?eoaaiiy aeyaeeiny iaea?eueo aoaeoeaiei a in?a ?c noaiiea?ae??th, ui aia?oa aeieeea i?ney A?I, o yeeo iiaeeeai i?aeaeuaiiy ??aiy caeeoeiai? i?aoeacaeaoiino? aei ??aiy I ooieoe?iiaeueiiai eeano. A?aoiaoth/e, ui o 50% oeeo oai?eo aeyaeai? aeenoaeuei? oa iaeiinoaeeii? o?aaeaiiy EA i?e EAA, a oaeiae i?enooi?noue aacinianoe/iiai oaeoi?o a ?icaeoeo ?IN, i?iaaaeaiiy o??o?a?/iiai e?eoaaiiy oae?e eaoaai??? iaoe??io?a iio?aao? ia iaeiicia/iiai ??oaiiy. Aecia/ai? e?eoe/ii iaaeaaii?e?ii? iciaee aeey i?aeaeuaiiy caeeoeiai? i?aoeacaeaoiino? oa e?eoa??? iai?aaeaiiy oeeo oai?eo ia o??o?a?/io ei?aeoe?th. A?eueo iecueea a?aeiiaeaiiy caeeoeiai? i?aoeacaeaoiino? c? noaa?eueiith noaiiea?ae??th, ui ia?aaeoaaea ?IN oa ??aee? o?aaeaiiy aeenoaeueieo a?aeae?e?a ei?iia?ieo a?oa??e aeicaiey? aaaaeaoe oeae eiioeiaaio iaea?eueo iieacaiei aeey o??o?a?/ieo ao?o/aiue. Oaeiae aeiaaaeaia aeioe?euei?noue i?iaaaeaiiy OI o oai?eo A?I aac ?IN. A E N I I A E E 1. O oiae? aeine?aeaeaiiy ciaeaeaia iaiaeii??aei?noue ia?aa?ao ?IN, ui aeeeoo? iaiao?aei?noue aeeoa?aioe?aoe?? a no?oeoo?? oeueiai neiioiiieiiieaeno aeaio eaoaai??e oai?eo: 1 a?oia, o yeeo ?IN aeieea? ia oii? noaiiea?ae??, ui ia?aaeoaaea A?I oa 2 a?oia – o yeeo ?IN aeieea? i?ney A?I aia?oa. 2. Anoaiiaeaii, ui ?IN /ano?oa aeieea? o oai?eo i?ney ae??aii-aiaieuaaiai, iiaoi?iiai o?aaeaiiy oa ia oii? a?ia?oii?/ii? oai?iae o ii??aiyii? c a?oiith eiio?ieth. 3. Iie?auaiiy ee?i?/iiai noaio oai?eo c ?IN a aeeiai?oe? a?eueo cia/ia o 2 a?oi? – 54,5% o ii??aiyii? c iaoe??ioaie 1 a?oie – 38,5%. ?icaeoie ?IN ia caeaaeeoue a?ae nooiaith ii?ooaiue aioo??oiueina?oeaai? aaiiaeeiai?ee. 4. ?a?no?aoe?y i?iea?ae?aeueii? ?oai?? o 41,7% iaoe??io?a a?oie eiio?ieth i?e a?aenooiino? ee?i?/ii? neiioiiaoeee aeicaiey? a?aeianoe oeth eaoaai??th oai?eo aei a?oio i?aeaeuaiiai ?eceeo. 5. Iayai?noue oee?eaaeiino? ?icaeoeo ?oai?? a ianoaaeaieo a?oiao ?IN (56% I? ?a?no?o?oueny o aa/??i? oa i?/i? aiaeeie) oa ci?ie iieaciee?a a?ieia?/ii aeoeaieo ?a/iaei aeicaieythoue i?eionoeoe iayai?noue ooieoe?iiaeueiiai oaeoi?o a aaiac? ?IN. 6. O iaoe??io?a c ?IN, a ia?oo /a?ao 1 a?oie, o ii??aiyii? c a?oiith eiio?ieth ae?aaiinooaaeinue aaaaoinoaeeiia o?aaeaiiy (45% i?ioe 19,2%). O oai?eo c ?IN ??aeoa i?ae o a?oi? eiio?ieth a?aei?/aeiny i?ieneiaeueia (25,0% oa 44,4%) oa /ano?oa aeenoaeueia (50,0% oa 22,3%) o?aaeaiiy. 7. Iaaeeeaiaioicia e?eoaaiiy iaea?eueo aoaeoeaia a in?a c? noaiiea?ae??th, ui aia?oa aeieeea i?ney A?I, o yeeo iiaeeeai i?aeaeuaiiy caeeoeiai? i?aoeacaeaoiino? aei ??aiy I ooieoe?iiaeueiiai eeano. I?AEOE*I? ?AEIIAIAeAOe?? 1. I?e a?aenooiino? aoaeoo iaaeeeaiaioicii? oa?ai?? o oai?eo ?IN i?ioyaii aeaio i?nyoe?a i?ney A?I aeey ae??oaiiy ieoaiue iiaeaeueoi? oaeoeee e?eoaaiiy iieacaii i?iaaaeaiiy EAA. 2. Oai?ei c ?IN, ye?e ia?aaeoaaea noaa?eueia noaiiea?ae?y ia?aae A?I ?aeiiaiaeiaaia i?ecia/aiiy ?aieiaeo i?eeii?a i?aia?ao?a c iaoith iiia?aaeaeaiiy neiae?iio “?icoiaeaeoaaiiy”. 3. Iayai?noue a aaiac? ?IN ooieoe?iiaeueiiai oaeoi?a aeeeoo? iaiao?aei?noue i?ecia/aiiy aeai?e eaoaai??? oai?eo ?aoa?aeieo aioaaii?no?a eaeueoe?th i?oaaeei?iiaiai ?yaeo. 4. C iaoith aeyaeaiiy a?oi i?aeaeuaiiai ?eceeo iieacaia aeioe?euei?noue i?iaaaeaiiy OI o oai?eo A?I aac ?IN. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Ooiaeia A.A., Neaaecaaneay E.E., Aoaianiaa I.A., Iaeeiianeay E.Y. Nia?aiaiiua i?aaenoaaeaiey i ?aiiae iinoeioa?eoiie noaiiea?aeee. // A?a/. aeaei.- 1997. - ?2.- N. 15-19. 2. Neaaecaaneay E.E., Ooiaeia A.A., Iaeeiianeay E.Y., Aaaee E.I., Eoeaoee I.A., Oiiaiei TH.I., Ua?aae ss.TH., Aoaianiaa I.A. Oea?eeeyoeey aeaeoaei/ea o aieueiuo eioa?eoii ieiea?aea: oaeoi?u, ii?aaeaeythuea i?iaiic //A?a/.aeaei. - 1997. - ?4. - N. 46-48. 3. Neaaecaaneay E.E., Ooiaeia A.A., Ia?oiiaiei A.I., Nieieia TH.I., Eoeaoee I.A., Iaeeiianeay E.Y., Aaaee E.I., Aoaianiaa I.A. Iniaaiiinoe oa/aiey noaiiea?aeee o aieueiuo n eioa?eoii ieiea?aea a caaeneiinoe io i?iaiaeeiiai ea/aiey. // Oe?. ea?ae. aeo?iae. - 1997. - ?4. - N. 5-7. 4. Aoaianiaa I.A. ?aiiyy iinoeioa?eoiay noaiiea?aeey: iaoi-oeceieiae/aneea iaoaieciu, eeeieei-aiaeia?aoe/aneea ia?aeeaee, oa?aiaaoe/aneea iiaeoiaeu e i?iaiic.// Oe?.ea?ae.aeo?iae. - 1998. - ?3. - N. 60-65. 5. Aoaianiaa I.A. Iniaaiiinoe aioo?ena?aea/iie aaiiaeeiaieee o aieueiuo n ?aiiae iinoeioa?eoiie noaiiea?aeeae.// Oe?.ea?ae.aeo?iae. - 1998. - ?4. -N. 13-15. 6. Neaaecaaneay E.E., Ooiaeia A.A., Aoaianiaa I.A., Oiiaiei TH.I., Aieoaue I.N., Iaeiianeay E.Y. Eeeieei-ooieoeeiiaeueiua iniaaiiinoe e inoaoi/iay ?aaioi-niiniaiinoue o aieueiuo n ?aiiae iinoeioa?eoiie noaiiea?aeeae.// Oe?.ea?ae.aeo?iae. - 1998. - ?5. - N. 14-17. 7. Neaaecaaneay E.E., Aoaianiaa I.A., Ooiaeia A.A., Oiiaiei TH.I., Aaaee E.I., Iaeeiianeay E.Y. Aic?anoiua iniaaiiinoe ?acaeoey e oa/aiey ?aiiae iinoeioa?eoiie noaiiea?aeee. // Iaoa?eaeu iaoe.-i?aeo. Eiioa?aioe??: ?aaa?e?oaoe?y oai?eo iioeeiai a?eo ?c caoai?thaaiiyie na?aeoeaai-noaeeiii? nenoaie ? oea?aa?aeueiith noaeeiiith iaoieia??th. - Ee?a. - 1997. - N. 15-17. Aoaianiaa I.A. ?aiiy iino?ioa?eoia noaiiea?ae?y: ee?i?/ia oa?aeoa?enoeea, ooieoe?iiaeuei? iniaeeaino?, a?aeiiaeaiiy i?aoeacaeaoiino?. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.11 - ea?ae?ieia?y. - Oe?a?inueeee iaoeiai - aeine?aeiee ?inoeooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea IIC Oe?a?ie, Ee?a, 1999. Aeena?oaoe?y i?enay/aia anoaiiaeaiith ee?i?ei-ooieoe?iiaeueieo e?eoa???a ia’?eoea?caoe?? noaio oai?eo aino?ei ?ioa?eoii i?iea?aea c ?aiiueith iino?ioa?eoiith noaiiea?ae??th. Ia i?aenoaa? ?acoeueoao?a ianoaaeaiiy a aeeiai?oe? 100 oai?eo (48 c ieo c ?aiiueith iino?ioa?eoiith noaiiea?ae??th) aoee ?ic?iaeai? ee?i?ei-ae?aaiinoe/i? caoiaee, oa?aiaaoe/ia oaeoeea aaaeaiiy oai?eo c aeaaii?e?iiei ia?aa?aii oai?iae oa aenieei ?eceeii ?icaeoeo oneeaaeiaiue, iieacaiue ui aei aecia/aiiy no?ie?a iai?aoeacaeaoiino? oa o??o?a?/iiai ao?o/aiiy. Oae, iino?ioa?eoia noaiiea?ae?y aeinoia??ii /ano?oa aeieea? o oai?eo i?ney ae??aiiaiaieuaaiai oa iiaoi?iiai o?aaeaiiy, a oaeiae ia oii? a?ia?oii?/ii? oai?iae. ?? ?icaeoie ia caeaaeeoue a?ae nooiaith ii?ooaiue aioo??oiueina?oeaai? aaiiaeeiai?ee. Oee?eaaei?noue ?icaeoeo ?oai?? oa ci?ie iieaciee?a a?ieia?/ii aeoeaieo ?a/iaei aeicaieythoue i?eionoeoe iayai?noue ooieoe?iiaeueiiai oaeoi?o a aaiac? ?aiiuei? iino?ioa?eoii? noaiiea?ae??. I?aeaeuaiiy caeeoeiai? i?aoeacaeaoiino? /ano?oa niinoa??-aa?oueny a in?a c? noaiiea?ae??th, ui aia?oa aeieeea i?ney ?ioa?eoo, a oie /an ye oai?? c noaiiea?ae??th aei ? i?ney ?ioa?eoo iio?aaothoue o??o?a?/iiai ao?o/aiiy. Aoaianiaa I.A. ?aiiyy iinoeioa?eoiay noaiiea?aeey: eeeie/aneay oa?aeoa?enoeea, ooieoeeiiaeueiua iniaaiiinoe, ainnoaiiaeaiea o?oaei-niiniaiinoe.- ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.11 - ea?aeeieiaey. - Oe?aeineee iao/ii-enneaaeiaa-oaeueneee einoeooo ea?aeeieiaee ei.aeaae. I.Ae. No?aaeanei IC Oe?aeiu, Eeaa, 1999. N oeaeueth eco/aiey eeeieei-ooieoeeiiaeueiuo iniaaiiinoae oa/aiey EAN o aieueiuo ino?ui eioa?eoii ieiea?aea n ?aiiae iinoeioa?eoiie noaiiea?aeeae, ?ac?aaioee iaoiaeia iiauoaiey yooaeoeaiinoe ea/aiey, ainnoaiiaeaiey o?oaeiniiniaiinoe e aoi?e/iie i?ioeeaeoeee iiaoi?iuo ei?iia?iuo eaoano?io ianeaaeiaaii 100 aieueiuo n ino?ui eioa?eoii ieiea?aea a ino?ue ia?eiae e a aeeiaieea ( 48 ec ieo - aieueiua n ?aiiae iinoeioa?eoiie noaiiea?aeeae), eioi?ui i?iaiaeeee ouaoaeueiue aiaeec eeeie/aneiai oa/aiey ?aiiae iinoeioa?eoiie noaiiea?aeee, ioeaieo ooieoeeiiaeueiiai ninoiyiey eaaiai aeaeoaei/ea, inoaoi/iie ?aaioi-niiniaiinoe e iniaaiiinoae iieacaoaeae oieoa?ianeiai iiieoi?e-?iaaiey, eco/aiey oa?aeoa?a ii?aaeaiey ei?iia?iuo a?oa?ee. Ia iniiaaiee i?iaaaeaiey oe?ieiai niaeo?a enneaaeiaaiee inouanoaeai aiaeec iieo/aiiuo ?acoeueoaoia aeey onoaiiaeaiey eeeieei - ooieoeeiiaeueiuo iniaaiiinoae ?aiiae iinoeioa?eoiie noaiiea?aeee, ?ac?aaioaiu eeeieei-aeeaaiinoe/aneea iiaeoiaeu, oa?aiaaoe/aneay oaeoeea, iieacaiey e ii?aaeaeaieth n?ieia iao?oaeiniiniaiinoe e oe?o?ae/aneiio aiaoa-oaeuenoao. A oiaea i?iaaaeaiiiai enneaaeiaaiey auaeaeaiu eeeie/aneea a?oiiu n ?aiiae iinoeioa?eoiie noaiiea?aeeae, a eioi?uo aeinoeaioo yooaeo i?e eiina?aaoeaiii ea/aiee, aeinoaoi/iii aeey ainnoaiiaeaiey ?aaioiniiniaiinoe ia o?iaia eaaeie ?aaiou. Iaaeeeaiaioiciia ea/aiea ieacaeinue iaeaieaa yooaeoeaii o eeoe ni noaiiea?aeeae, aia?aua aicieeoae iinea ino?iai eioa?eoa ieiea?aea, o eioi?uo aiciiaeii iiauoaiea o?iaiy inoaoi/iie ?aaioiniiniaiinoe aei o?iaiy II ooieoeeiiaeueiiai eeanna. O/eouaay, /oi o 50% yoeo aieueiuo auyaeaiu aeenoaeueiua e iaeiininoaeenoua ii?aaeaiey ei?iia?iuo a?oa?ee i?e ei?iia?i-aiaeia?aoee, a oae aea i?enoonoaea aacinianoe/aneiai oaeoi?a a ?acaeoee ?aiiae iinoeioa?eoiie noaiiea?aeee; i?iaaaeaiea oe?o?ae/aneiai ea/aiey yoie eaoaai?ee iaoeeaioia o?aaoao iaiaeiicia/iiai ?aoaiey. Ii?aaeaeaiu e?eoe/anee iaaeaaii?eyoiua i?eciaee aeey iiauoaiey inoaoi/iie ?aaioiniiniaiinoe e, neaaeiaaoaeueii, e?eoa?ee iai?aaeaiey yoeo aieueiuo ia oe?o?ae/aneoth ei??aeoeeth. Aieaa ieceia ainnoaiiaeaiea inoaoi/iie ?aaioiniiniaiinoe o aieueiuo n i?aaeoanoaiaaaoae ?aiiae iinoeioa?eoiie noaiiea?aeee noaaeeueiie noaiiea?aeeae e ?aaeeea ii?aaeaiey aeenoaeueiuo ioaeaeia ei?iia?iuo a?oa?ee iicaieyao n/eoaoue yoio eiioeiaaio iaeaieaa iieacaiiui aeey oe?o?ae/aneeo aiaoaoaeuenoa. Iieacaia oeaeaniia?aciinoue i?iaaaeaiey oieoa?ianeiai iiieoi?e?iaaiey o aieueiuo ino?ui eioa?eoii ieiea?aea aac ?aiiae iinoeioa?eoiie noaiiea?aeee. Atanasova N.V. Early postinfarction angina: clinical characteristics, functional peculiarities, recovery of capacity for work. - Manuscript. Thesis for a candidate’s degree by speciality 14.01.11 - cardiology. - The Ukrainian Research Institute of Cardiology of Healthy of Ministry of Ukraine, Kyiv, 1999. Dissertation is devoted to the problem of definition of clinical and functional peculiarities in patients with acute myocardial infarction which was complicated by development of early postinfarction angina. On the results of investigation of 100 patients (postinfarction angina was in 48 of them) it was established clinical and diagnostical methods, therapeutical tactics in patients with favourable course of disease and high risk of development of complications, indications for definition of dates of capacity for work and surgical intervention. Early postinfarction angina was developed more often in patients with non-Q wave myocardial infarctions and reinfarctions and on the background of arterial hypertension. Its development does not depend on intracardiac hemodynamic. Circadian rhythm of ischemia and changes of biological active substances suppose the presense of functional factor in genesis of early postinfarction angina. Increasing of capacity for work is observed more often in patients, in whom angina was developed for the first time only after myocardial infarction, at same time patients with angina which was developed before infarction and preserved after it were need in surgical intervention. IA?AE?E OIIAIEO IICIA*AIUe AA?I - aacaieueiaa ?oai?y i?iea?aea A?I - aieueiaa ?oai?y i?iea?aea AAI - aaeia?aiiao??y A?I - aino?ee ?ioa?eo i?iea?aea AO - a?ia?oii?/ia oai?iaa AEA - aeaeo?iea?ae?ia?ao?y AoiEA - aoiea?ae?ia?ao?y ?I - ?ioa?eo i?iea?aea ?ON - ?oai?/ia oai?iaa na?oey EA - ei?iia?ia a?oa??y EAA - ei?iia?iaia?ia?ao?y EAeI - e?ioeaai-ae?anoie?/i?e ia’?i ENI - e?ioeaai-n?noie?/iee ia’?i I? - i?iea?ae?aeueia ?oai?y ?IN - ?aiiy iino?ioa?eoia noaiiea?ae?y OA - o?aeoe?y aeeeaeo OI - oieoa??anueea iii?oi?oaaiiy

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