i?i?noa?noai ioi?iie caei?ia’y oe?a?ie

oe?a?inueea iaaee/ia noiiaoieia?/ia aeaaeai?y

Ia i?aaao ?oeiieno

OAeE 616.716.8-002-053.2-085

OEA*AIEI Iaaei ?aaiiae/

iaoiaaiaoe/i? iniaeeaino? caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee
o ae?oae oa aeeoa?aioe?eiaai? i?aeoiaee aei ?o

e?eoaaiiy

14.01.22 – noiiaoieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Iieoaaa –1998

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Oe?a?inuee?e iaaee/i?e noiiaoieia?/i?e aeaaeai?? IIC
Oe?a?ie (?aeoi? – aeieoi? iaaee/ieo iaoe, i?ioani?, caneoaeaiee ae?y/
iaoee ? oaoi?ee Oe?a?ie I.N.Ne?eii?eia) ia eaoaae?? aeeoy/i?
noiiaoieia??.

Iaoeia? eiinoeueoaioe: aeieoi? iaaee/ieo iaoe, i?ioani?, caneoaeaiee
ae?y/ iaoee ? oaoi?ee Oe?a?ie Ne?eii?eia Ieeiea Na?a?eiae/, Oe?a?inueea
iaaee/ia noiiaoieia?/ia aeaaeai?y, caa?aeoaa/ eaoaae?e iia?aoeaii?
o??o?a?? oa oiiia?ao?/ii? aiaoii??

aeieoi? iaaee/ieo iaoe, i?ioani? ?EAAEIA Ieaa Aaneeueiae/, Oe?a?inueea
iaaee/ia noiiaoieia?/ia aeaaeai?y, caa?aeoaa/ eaoaae?e o??o?a?/ii?
noiiaoieia??

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani?, caneoaeaiee ae?y/
iaoee ? oaoi?ee Oe?a?ie EOOeAAEssE Aaea??e ?na?ae/, Oa?e?anueeee
aea?aeaaiee iaaee/iee oi?aa?neoao, caa?aeoaa/ eaoaae?e aeeoy/i?
noiiaoieia??

aeieoi? iaaee/ieo iaoe, i?ioani? OA?UeEIA Eaii?ae A?eoi?iae/,
Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?iai? aeaaeai?ea I.I.Aiaiiieueoey,
caa?aeoaa/ eaoaae?e aeeoy/i? o??o?a?/ii? noiiaoieia??

aeieoi? iaaee/ieo iaoe, i?ioani? AeE*EI ?aaai Ieeeoi?iae/,
Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y, caa?aeoaa/ eaoaae?e
aeeoy/i? noiiaoieia??

I?ia?aeia onoaiiaa: Euea?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao IIC
Oe?a?ie, eaoaae?a aeeoy/i? noiiaoieia??

Caoeno a?aeaoaeaoueny “22” a?oaeiy 1998 ?ieo i 11 aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? A/aii? ?aaee Ae 44.601.01 i?e Oe?a?inuee?e iaaee/i?e
noiiaoieia?/i?e aeaaeai?? (314024, i. Iieoaaa, aoe. Oaa/aiea, 23).

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? aeaaeai?? ca
aae?anith i.Iieoaaa, aoe. Oaa/aiea, 23.

Aaoi?aoa?ao ?ic?neaiee “6” eenoiiaaea 1998 ?ieo.

A/aiee nae?aoa?

niaoe?ae?ciaaii? A/aii? ?aaee,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
I.A.Aieiaei

2

caaaeueia oa?aeoa?enoeea ?iaioe

Aeooaeuei?noue oaie. Caiaeuei? i?ioeane uaeaiii-eeoeaai? ae?eyiee (CI
UEAe) o ae?oae caeiathoue /?eueia i?noea a iiiaieeaoo?? noiiaoieia?/ieo
caoai?thaaiue. Oea iaoiiaeaii ?o cia/iith /anoioith,
?iciianthaeaeai?noth ? iie?ii?o?ciii ee?i?/ieo i?iya?a (A.A.?iaeinueeee
? ni?aaao., 1983; I.A.?eaaeia, 1987; TH.A.THnoaia, 1988;
O.E.Aeoniooaiaaeiaa, 1994; E.A.Oa?ueeia, A.?.Eooeaaeye, 1997). A ?o
no?oeoo?? i?aaaeththoue e?ioaaeai?oe, aaeaiioeaaiiie, iaeiioiaaiiee
inoaii??e?o ? n?aeaaeai?oe (I.A.?eaaeia, 1987; I.I.Oeiioa?a,
?.A.E?iae?anue, 1997; E.A.Oa?ueeia ? ni?aaao., 1997).

E??i e?euee?nieo a?aei?iiinoae a oiiaao nueiaiaeaiiy a?aecia/a?oueny
aa?aneaiee ia?aa?a aino?eo caiaeueieo i?ioean?a, ia?ao?ae ?o a o?ii?/io
oi?io, ii/ano?oaee aeiaaeee oyaeeeo oneeaaeiaiue (?.A.Aoiaaeeoiaa, 1993;
TH.Oa/e?ia ? ni?aaao., 1993; A.A.Oeaioeei, 1996; R.H.Hang et.al., 1990).

?noioi? ci?ie a ee?i?/iiio ia?aa?c? aino?eo iaeiioiaaiieo ?
iaiaeiioiaaiieo caiaeueieo caoai?thaaiue iaoiiaeai? c?inoaiiyi no?eeino?
caoaeiee?a aei aioea?ioee?a ? ii?ooaiiyi ?ioiieia?/ii? ii??iino?
i?aai?cio, iia’ycaieo c ia?aoe?iiaeueiei e?eoaaiiyi, i?aeaeuaiiyi ??aiy
nainea?e?caoe?? oa iia??oaiiyi aeieia?/iiai noaio ioi/oth/iai
na?aaeiaeua (A.I.Iaeueie/aiei, 1993; ?.I.Aioue ? ni?aaao., 1994;
O.E.Aeoniooaiaaeiaa, 1994; A.I.?oc?i ? ni?aaao., 1995; I.I.Oeiioa?a,
1995).

Ianooaai? aeieia?/i? iaaa?acaee ?iaeyoue iaiao?aeiei ocaaaeueiaiiy
ai?aeai?ieia?/ieo, aenia?eiaioaeueieo ee?i?/ieo aeaieo oa no/anieo
iaoiaaiaoe/ieo eiioeaioe?e aieeao aeciaaiieo oa aiaeiaaiieo oaeoi??a ia
i?aai?ci (TH.A.A?eiaae/, A.E.Aaioe, 1993; I.?.?oaeiaa ? ni?aaao., 1994;
I.?.Niiey?, C.?.I?eoei, 1994; A.I.Ooiaeei, 1996).

Eiiieaenia o??o?a?/ia ? iaaeeeaiaioicia e?eoaaiiy caiaeueieo
caoai?thaaiue ia iiaea aooe iiaiioe?iiei aac /?oeiai ?icoi?iiy ?ioiieo
ii?ooaiue, iaoai?ci?a ?o aeieeiaiiy ? oeyo?a ei?aeoe?? (A.I.Ae?aii?e ?
ni?aaao., 1994; I.O.?aaieoeueea ? ni?aaao., 1995; A.I.Caineia ?
ni?aaao., 1997).

I?eionea?oueny, ui iaia?aiiaeanoaa?e?coth/? iaoai?cie oi?aa?naeuei? aeey
a?ieia?/ieo nenoai ? ia caeaaeaoue a?ae oa?aeoa?o iaoieia?/iiai i?ioeano
(caiaeaiiy, o?aaia ? ?io.). I?e ?o iaaei??i?e aeoeaiino?, ni?iaieiaai?e
?ioaeoe?eiei, aea?a?/iei, ?ioiieia?/iei oaeoi?aie aeai? /eiieee
ii/eiathoue a?ae?a?aaaoe i?iaieoth/o ?ieue a caioneo eaioethaiai?
?aaeoe??, iai?aaeaii? ia aeoea?caoe?th aeanoaa?e?caoe?? ee?oeiieo
iaia?ai (A.A.Aa?aaie ? ni?aaao., 1991; TH.A.Aeaae?i??ia ? ni?aaao.,
1991; I.I.Aine?anainueeee, A.I.Oea/aiei, 1991).

E??i oiai, i?e aeieeiaii? caiaeueieo i?ioean?a ?icaeaathoueny
iae?i-aiaeie?eii? ii?ooaiiy, ye? i?iyaeythoueny aeenaaeainii o
ooieoe?thaaii? aiaeie?eiii? nenoaie (I.N.?aaea?eue, 1991; A.A.Aa?y/eo ?
ni?aaao., 1991).

Iniaeeai a?ae/ooii oe? ci?ie i?iyaeythoueny o in?a, ui i?aeeyaee ae??
?ii?coth/iai aei?ii?ithaaiiy (TH.?.Iineaeaa, 1991; ?.A.Aaaaeana?iaa,
N.I.Oii?ia, 1995; O.TH.Aaae/, 1996).

Oaeei /eiii, no/ania i?ia?aeia eiioeaioe?y iaoiaaiaco caiaeueieo
caoai?thaaiue aaco?oueny ia oyaeaii? i?i nooo?ao ?ieue ?ioiieo,
iaia?aiiaeanoaa?e?coth/eo oa aiaeie?eiieo i?ioean?a ? iaoai?ci?a, ye? ?o
?aae?cothoue. ? ana ae, ia oaia??oi?e /an, ie?ai? eaioethae iaoiaaiaco
caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee, iniaeeai o ae?oae, a
aeinoaoi?e i??? ia aena?oeai?.

A?aenooi?noue iiaeeaeaieo ciaiue i?i neeaaeia? ?o iaoiaaiaco ni?e/eiy?
a?aeiia?aei? o?oaeiiu? o ae??oaii? ieoaiiy i?aeaeuaiiy yeino? aeiiiiiae
oai?ei oe??? eaoaai??? ca ?aooiie aeeoa?aioe?eiaaiiai e?eoaaiiy, ui
i?aaenoaaey? oai?aoe/io ? i?aeoe/io aeooaeuei?noue i?iaeaie.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa ? o?aaiaioii iaoeiai-aeine?aeieoeueeeo ?ia?o: “Iaoai?cie
iioeiaeaeaiiy coai-uaeaiii? nenoaie, ?acenoaioi?noue i?aai?cio ?
iaa?oiooaaiy cania?a i?io?eaeoeee, oa?ai?? ? ?aaa?e?oaoe?? iniiaieo
noiiaoieia?/ieo caoai?thaaiue” ? aea?aeaaii? ?a?no?aoe?? 0197V018550 ?
“Aea/aiiy ?ie? aca?iica’yceo a?eueii?aaeeeaeueieo, aaiieiaaoethth/eo,
?ioiieo iaoai?ci?a o iaoiaaiac? caoai?thaaiue, iia’ycaieo c ae??th
i?aeaeuaieo aeic ?ii?coth/iai aei?ii?ithaaiiy oa ?ic?iaea iaoiae?a ?o
iaoiaaiaoe/ii? ei?aeoe?? iaia?aiinoaa?e?coth/eie oa iie?iaioeaeieie
i?aia?aoaie” ? aea?aeaaii? ?a?no?aoe?? 0193V024034.

Iaoa ?iaioe – ia i?aenoaa? eiiieaeniiai aeine?aeaeaiiy eaioetha?a
iaoiaaiaco caiaeueieo caoai?thaaiue uaeaiii-eeoeaai? ae?eyiee o ae?oae
i?aeaeueoe aoaeoeai?noue ?o e?eoaaeueieo, i?io?eaeoe/ieo ?
?aaa?e?oaoe?eieo caoiae?a.

Aeey aeinyaiaiiy iinoaaeaii? iaoe iaiao?aeii aoei ae??oeoe ne?aeoth/?
caaea/?:

1. Aea/eoe iniaeeaino? ee?i?ei-eaai?aoi?ieo oa?aeoa?enoee iaeiioiaaiieo
? iaiaeiioiaaiieo caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee o
ae?oae c a?aooaaiiyi aioa- ? iinoiaoaeueiiai ia??iae?a ?icaeoeo.

2. Aeaoe i?e?ia?ieia?/io ? ?ioiieia?/io oa?aeoa?enoeee ??cieo
iicieia?/ieo oi?i caiaeueieo i?ioean?a.

3. Aeine?aeeoe noai i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a (IIE) ?
oaeoi??a aioeieneaeaioiiai caoenoo (AIC) e?ia?, ?ioiai? ??aeeie oa
ia?ioeaeiiai nae?aoo.

4. Aecia/eoe aieea caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee ia
ooieoe?iiaeueiee noai aiaeie?eiieo caeic oa anoaiiaeoe ?o cia/aiiy a
caoenii-eiiiainaoi?ieo ?aaeoe?yo i?aai?cio.

5. Ia i?aenoaa? ioe?iee io?eiaieo ?acoeueoao?a ?ic?iaeoe a?iioaoe/io
noaio ao?iiaoiaaiaco aino?eo caiaeueieo caoai?thaaiue uaeaiii-eeoeaai?
ae?eyiee oa caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo (OII) o
ae?oae, iioei?coaaoe oaeoeeo eiiieaeniiai e?eoaaiiy ?o ca ?aooiie
aeeoa?aioe?eiaaiiai canoinoaaiiy ?ioiiei?aaoth/eo,
iaia?aii-noaa?e?coth/eo i?aia?ao?a ? aaeaioiaaio. Ai?iaaaeeoe a i?aeoeeo
?ic?iaeai? iaoiaee e?eoaaiiy, aecia/eoe ?o aeiiii?/io aoaeoeai?noue.

Iaoeiaa iiaecia. A ?iaio? aia?oa i?aaenoaaeaia ee?i?ei-eaai?aoi?ia
oa?aeoa?enoeea aino?eo caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee ?
o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o ae?oae c o?aooaaiiyi iniaeeainoae
ia?aa?ao aioa- oa iinoiaoaeueiiai ia??iae?a ?o ?icaeoeo.

Aia?oa anoaiiaeaii, ui ?icaeoie caiaeueieo caoai?thaaiue
uaeaiii-eeoeaai? ae?eyiee o ae?oae caeiiii??ii noi?iaiaeaeo?oueny
noi?an??th ee?oeiieo ? aoii?aeueieo oaeoi??a caoenoo e?ia?, ?ioiai?
??aeeie oa ia?ioeaeiiai nae?aoo, a?eueo ae?aaeaio o ae?oae, ye? i?aeiaee
ae?? ?ii?coth/iai aei?ii?ithaaiiy.

Aia?oa aecia/aii, ui nooi?iue aeoea?caoe?? i?ioean?a ia?aeeniiai
ieeneaiiy e?i?ae?a i?e caiaeueieo caoai?thaaiiyo uaeaiii-eeoeaai?
ae?eyiee iia’ycaiee ia o?eueee c aaciina?aaeiueith ae??th
iaia?aiiaeanoaa?e?coth/eo iaoai?ci?a, aea iaoiiaeaia ? aeao?oeeoii
oaeoi??a aioeieneaeaioiiai caoenoo.

Aia?oa o ae?oae c ??cieie iicieia?/ieie oi?iaie caiaeueieo i?ioean?a
uaeaiii-eeoeaai? ae?eyiee i?iaaaeaia eiiieaenia ioe?iea eiioeaio?aoe??
ai?iii?a (OOA, O3, O4, ei?oecieo, ?inoe?io) a ne?iaaooe? e?ia? a
aeeiai?oe? e?eoaaiiy.

Aia?oa anoaiiaeaii, ui ia /an ee?i?/iiai iaeoaeaiiy o ia?aaaaeii?
a?eueoino? ae?oae, ye? io?eioaaee o?aaeeoe?eia e?eoaaiiy, ? iniaeeai o
oai?eo, ye? i?aeiaee ae?? ?ii?coth/iai aei?ii?ithaaiiy, ia
a?aeaoaa?oueny ii?iae?caoe?? iieaciee?a ?ioi?oaoo, ia?aeeniiai ieeneaiiy
e?i?ae?a, aioeieneaeaioiiai caoenoo oa ai?iiiaeueiiai noaoono.

Ia iniia? i?iaaaeaieo aeine?aeaeaiue aia?oa i?aaenoaaeai? oi?aa?naeuei?
neeaaeia? eiiiiiaioe iaoiaaiaco aino?eo caiaeueieo caoai?thaaiue
uaeaiii-eeoeaai? ae?eyiee oa caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai
ia?ioeoo o ae?oae, ui aeicaieeei ia’?aeiaoe ?o a a?iioaoe/io noaio
ao?iiaoiaaiaco.

Aia?oa cai?iiiiiaaii a e?eoaaii? aino?eo caiaeueieo i?ioean?a
uaeaiii-eeoeaai? ae?eyiee ? o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o
ae?oae aeey caaaeueiiai ? i?noeaaiai canoinoaaiiy aeeoa?aioe?eiaai?
eiia?iaoe?? e?ea?nueeeo cania?a, yeei i?eoaiaii? ?ioiiei?aaoth/?,
aioeieneaeaioi? oa aaeaioiaaii? aeanoeaino?.

I?aeoe/ia cia/aiiy. I?aeoe/iei e?ea?yi-noiiaoieiaai cai?iiiiiaaii
eiiieaen aeinooiieo eaai?aoi?ieo iaoiae?a ianoaaeaiiy ae?oae c aino?eie
iaeiioiaaiieie ? iaiaeiioiaaiieie caiaeueieie i?ioeanaie
uaeaiii-eeoeaai? ae?eyiee oa o?ii?/iei ia?aio?iaoiciei ia?ioeoii.

C iaoith ia’?eoeaii? ioe?iee ia?aa?ao aino?eo caiaeueieo i?ioean?a
uaeaiii-eeoeaai? ae?eyiee oa o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o
ae?oae iaiao?aeii i?iaiaeeoe aeeiai?/iee eiio?ieue ca oeeoieia?/iith ?
i?e?ia?ieia?/iith ea?oeiith ?aiaaiai aenoaeaoo ? ia?ioeaeiiai nae?aoo.

Aeey i?iaiicoaaiiy ia?aa?ao caoai?thaaiiy oa aecia/aiiy aeioe?eueiino?
i?ecia/aiy eo?niai? aeice ?ioiiei?aaoth/eo i?aia?ao?a ne?ae i?iaiaeeoe
aecia/aiiy ee?oeiieo ? aoii?aeueieo oaeoi??a caoenoo a ne?iaaooe? e?ia?,
?ioia?e ??aeei? ? ia?ioeaeiiio nae?ao?. Cai?iiiiiaaii i?inoee o
aeeiiaii? iaoiae aecia/aiiy aaeoa?eoeeaeii? aeoeaiino? e?cioeeio a
?ioia?e ??aeei? oa ia?ioeaeiiio nae?ao?.

Aea/aiiy iieaciee?a ia?aeeniiai ieeneaiiy e?i?ae?a oa aioeieneaeaioiiai
caoenoo a e?ia?, ?ioia?e ??aeei? ? ia?ioeaeiiio nae?ao? i?aeoe/ii aea?
iiaeeea?noue aecia/aoe aoaeoeai?noue e?eoaaeueieo caoiae?a oa
eiio?iethaaoe i?ioean noaa?e?caoe?? ee?oeiieo iaia?ai.

Iii?oi??ia ca eiioeaio?aoe??th ai?iii?a a ne?iaaooe? e?ia? (OOA, O3,
ei?oecie) aeicaiey? ioe?ieoe aieea e?eoaaeueieo caoiae?a ia ia?aa?a
caoai?thaaiiy ? iaaea? i?aai aea??eiai aeei?enoiaoaaoe aaeaioiaaie.

Aeeoa?aioe?eiaaia canoinoaaiiy e?ea?nueeeo cania?a i?e caiaeueieo
i?ioeanao uaeaiii-eeoeaai? ae?eyiee ni?ey? iie?ioaiith ?o ee?i?/iiai
ia?aa?ao, nei?i/aiith no?ie?a ia?aaoaaiiy ia e?ea?iyiiio e?aeeo,
ciaioaiith e?eueeino? ? o?eaaeino? ?aoeeaeea?a o?ii?/iiai ia?ioeoo oa
i?iaeiaaeaiith eiai ?ai?n??. Caaaeueiee aeiiii?/iee aoaeo aea?aeaaieo
aeo?ao i?e iaaeaii? noaoe?iia?ii? ? aiaoeaoi?ii? aeiiiiiae oeei
eaoaai??yi oai?eo neeaa 370,13 a?eaaiue ca aeiao.

Iniaenoee aianie caeiaoaa/a. Aeena?oaoe?eia ?iaioa ? naiino?eiei
iaoeiaei aeine?aeaeaiiyi, aeeiiaiei ia aac? eaoaae?e noiiaoieia??
aeeoy/iai a?eo, oeaio?aeueii? iaoeiai-aeine?aeii? eaai?aoi???
Oe?a?inueei? iaaee/ii? noiiaoieia?/ii? aeaaeai??, Iieoaanueeiai
iaeaniiai oeaio?o ?aaa?e?oaoe?? e?ea?aeaoi??a aaa??? ia *AAN, aeeoy/eo
i?nueeeo noiiaoieia?/ieo iie?ee?i?e i. Iieoaae ? *a?i?aiaa,
uaeaiii-eeoeaaeo a?aeae?eaiiyo Iieoaanueei? oa *a?i?a?anueei? iaeanieo
e?ea?aiue, o??o?a?/iiio ? aaiaoieia?/iiio a?aeae?eaiiyo Iieoaanueei?
i?nueei? aeeoy/i? ee?i?/ii? e?ea?i?, oeaio?aeueii? i?nueei?
aaeoa??ieia?/ii? eaai?aoi??? i. Iieoaae. Naiino?eii i?iaaaeaii ee?i?/ia
? /anoeiai eaai?aoi?ia ianoaaeaiiy 50 caei?iaeo ae?oae, 830 oai?eo oa ?o
e?eoaaiiy, noaoenoe/ia ia?iaea aeaieo ? ?o ?ioa?i?aoaoe?y.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe aeine?aeaeaiue
iia?aeiieaii ? iaaiai?aii ia eiioa?aioe?yo iieiaeeo o/aieo (Iieoaaa,
1987-1988); eiioa?aioe?? iieiaeeo a/aieo c i?aeia?iaeiith o/anoth
(Iieoaaa, 1988); iaeanieo nai?ia?ao aeeoy/eo e?ea??a-noiiaoieia?a
(Iieoaaa, 1987-1997); i?nueeeo nai?ia?ao iaae?ao??a (Iieoaaa, 1987-1991,
1997); can?aeaiiyo iaeaniiai iaoeiaiai oiaa?enoaa noiiaoieia?a (Iieoaaa,
1988, 1991); ?anioae?eainuee?e iaoeia?e eiioa?aioe?? (Iieoaaa, 1991);
VII c’?cae? noiiaoieia?a O?N? (Euea?a, 1989); eiioa?aioe??, i?enay/ai?e
70-??//th IAeIN? (Iieoaaa, 1991); I?aeaea?aeaai?e iaoiaee/i?e ia?aae?
aeeniaina?ieo oeaio??a iaoieia?? neeiieo caeic (Iineaa, 1992);
Anaoe?a?inueeeo iaoeiai-i?aeoe/ieo eiioa?aioe?yo e?ea??a-noiiaoieia?a
(Iieoaaa, 1996; Iaeana, 1997; Ee?a, 1998); ?icoe?aiiio can?aeaii?
ai?iaaoe?eii? A/aii? ?aaee OINA (Iieoaaa, 1998).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 35 iaoeiaeo ?ia?o: o
oiio /ene? 15 noaooae o oeaio?aeueieo iaoeiaeo aeaeaiiyo ? 20 – o
ca??ieeao iaoeiaeo i?aoeue, 3 ?ioi?iaoe?ei? eenoe, io?eiaii iina?ae/aiiy
ia iaoaio oa 8 ?aoe?iiae?caoi?nueeeo i?iiiceoe?e.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy a i?aeoeeo. Oaeineiiaeai?
iaoiaee ianoaaeaiiy ae?oae c aino?eie caiaeueieie i?ioeanaie
uaeaiii-eeoeaai? ae?eyiee ? o?ii?/iei ia?aio?iaoiciei ia?ioeoii oa
?ic?iaeai? e?eoaaeuei? eiiieaene ai?iaaaeaeaii a ee?i?eao eaoaae?
noiiaoieia?? aeeoy/iai a?eo, o??o?a?/ii? noiiaoieia??, i?neyaeeieiiii?
i?aeaioiaee e?ea??a OINA, E?einueeiai iaaee/iiai ?inoeoooo; ee?i?eao
uaeaiii-eeoeaai? o??o?a?? Iieoaanueei? ? *a?i?a?anueei? iaeanieo
e?ea?aiue; o??o?a?/ieo a?aeae?eaiiyo aeeoy/eo e?ea?aiue i. Iieoaae,
*a?i?aiaa, E?aiai/oea; iaeanieo ? aeeoy/eo noiiaoieia?/ieo iie?ee?i?e
Noi, Aeiiaoeueea, Eueaiaa, AEeoiie?a, N?ioa?iiiey, Iinueea.

?ic?iaeai? iaoiaee aecia/aiiy aaeoa?eoeeaeii? aeoeaiino? e?cioeeio
?ioiai? ??aeeie ? ia?ioeaeiiai nae?aoo oa aea/aiiy ai?noo i?iaeoeo?a IIE
a ieo iaoiaeii oai?ethi?ianoeaioe?? aeei?enoiaothoueny a ?iaio?
Iieoaanueei? i?nueei? aaeoa??ieia?/ii? eaai?aoi??? oa OeIAeE OINA.

Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 231 noi??ioe?
cae?eiaiai iaoeiiieniiai oaenoo ? neeaaea?oueny ?c anooio, aiae?oe/iiai
iaeyaeo e?oa?aoo?e, iieno ia’?eo?a ? iaoiae?a aeine?aeaeaiiy, 8 aeaa
aeanieo aeine?aeaeaiue, ?ic?aooieo aeiiii?/ii? aoaeoeaiino?, iaaiai?aiiy
io?eiaieo ?acoeueoao?a, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e ? ia?ae?eo
e?oa?aoo?e, yeee i?noeoue 495 i?ei??iee?a a?o/eciyieo oa 150 ?iicaiieo
aaoi??a. ?iaioa ?ethno?iaaia 107 oaaeeoeyie ? 56 ?enoieaie.

ci?no ?iaioe

Ia’?eoe ? iaoiaee aeine?aeaeaiue. Iaoa??aee iniaenoiai aeine?aeaeaiiy
aacothoueny ia aiae?c? ?acoeueoao?a ee?i?ei-eaai?aoi?iiai ianoaaeaiiy
i?ioyaii 10 ?ie?a (1987-1997) 830 ae?oae c aino?eie ai?eieie caiaeueieie
i?ioeanaie uaeaiii-eeoeaai? ae?eyiee oa o?ii?/iei ia?aio?iaoiciei
ia?ioeoii. C aino?ei ai?eiei e?ioaaeai?oii niinoa??aaee 240 oai?eo
(29%), c aino?ei ai?eiei e?ioaaeai?oii o ae?oae, ye? i?aeiaee ae??
?ii?coth/iai aei?ii?ithaaiiy – 117 (14%), c aaeaiioeaaiiiith – 150
(18%), c aino?ei iaeiioiaaiiei inoaii??e?oii o?ea ieaeiuei? uaeaie – 147
(18%), c o?ii?/iei ia?aio?iaoiciei ia?ioeoii – 176 (21%). Oeii/ee?a aoei
448 (54%), ae?a/aoie – 382 (46%). A?e oai?eo a?ae 2 i?nyoe?a aei 15
?ie?a. Eiio?ieueio a?oio neeaee 50 i?aeoe/ii caei?iaeo ae?oae,
iaoeaioe?a i. Iieoaae o a?oe? a?ae 3 aei 15 ?ie?a.

Ee?i?/ia ianoaaeaiiy oai?eo neeaaeaeiny c caaaeueiiai iaeyaeo,
iieooaaiiy, c’ynoaaiiy nea?a, aiaiiaco caoai?thaaiiy oa aiae?co aioa- ?
iinoiaoaeueiiai ia??iae?a ?icaeoeo aeeoeie, ia?oeo neiioii?a
caoai?thaaiiy. Anoaiiaethaaeanue eieae?caoe?y ? iioe?aiiy caiaeueiiai
i?ioeano, oa?aeoa? aieth, aecia/aany caaaeueiee noai, oa?aeoa?
oaiia?aoo?ii? ?aaeoe??, ooieoe?iiaeuei? ii?ooaiiy. I?e iaiao?aeiino?
oai?? eiinoeueooaaeenue e?ea?yie ?ioeo niaoe?aeueiinoae. I?iaiaeeeanue
aeeiai?/ia a?coaeueia ioe?iea ai?eiiai aenoaeaoo ? ia?ioeaeiiai nae?aoo,
?o oeeoieia?/ia oa i?e?ia?ieia?/ia aeine?aeaeaiiy ca caaaeueiii?eeiyoeie
iaoiaeeeaie.

A ?iaio? ie ei?enooaaeenue eeaneo?eaoe??th aino?eo caiaeueieo i?ioean?a
oaeaiii-eeoeaai? ae?eyiee I.I.Nieioeaaa ? I.I.Oeiioa?aa (1989), a aeey
o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo eeaneo?eaoe??th I.A.?eaaeiaa
(1987). Noaae?? ia?aa?ao ?aiueiaiai i?ioeano ioe?ithaaee ca?aeii
?aeiiaiaeaoe?e I.?.Eoc?ia ? A.I.Einoth/aiea (1990).

Caa?? ia?ioeaeiiai nae?aoo i?e o?ii?/iiio ia?ioeo? ?iaeee c?aieo
iaouana?oea i?ioyaii 10 oaeeei aac noeioeyoe?? ca aeiiiiiaith
cai?iiiiiaaieo iaie ieanoeeiaeo eaoaoa??a (?aoe. i?iiiceoe?? ? 1650 a?ae
02.10.92 ?., ? 1696 a?ae 12.03.93 ?.).

Aecia/aiiy eaeeioeeoa?iiai ?iaeaeno ?ioieneeaoe?? i?iaiaeeee ca
oi?ioeith ss.ss.Eaeueo-Eae?oo (I.?.Eoc?i, A.I.Einoth/aiie, 1990).

Aeine?aeaeaiiy ?ioiiiai noaoono e?ia?, ?ioiai? ??aeeie, ia?ioeaeiiai
nae?aoo (O-, A-, I-e?ioioeeo?a, ?ioiiaeiaoe?i?a A, I, G, S IgA)
i?iaiaeeeinue ca aeiiiiiaith noaiaea?oieo ?ioiieia?/ieo oano?a
(E.A.Eaaaaeaa, ?.Ae.Iiiye?ia, 1990). Aaeoa?eoeeaeio aeoeai?noue
e?cioeeio ?ioiai? ??aeeie ? ia?ioeaeiiai nae?aoo aea/aee ca?aeii
?ic?iaeaii? iaie iaoiaeeee (I.?.Oea/aiei ? ni?aaao., 1993).

Aeeiai?eo iieaciee?a ia?aeeniiai ieeneaiiy e?i?ae?a oa aioeieneaeaioiiai
caoenoo a e?ia?, ?ioia?e ??aeei? oa ia?ioeaeiiio nae?ao? aea/aee ii
ai?noo ae??iiaeo eii’thaao?a (AeE) – (I.I.Aine?anainueeee, A.A.Ooiaiia,
1982), niiioaiiiio aaiie?co a?eo?ioeeo?a (NAA) – (A.A.Nie??/aa,
?.?.Iaooo?n, 1979), iaeiie/aiith iaeiiiaiai aeeaeueaeaa?aeo (IAeA) –
(TH.A.Aeaaeei??ia, A.?.A?/aeia, 1972), eaoaeace (I.A.A?o?iiaa, 1988),
noia?ieneaeaeeniooace (NIAe) – (I.N.A?onia ? ni?aaao., 1976),
oea?oeiieaci?io (E.I.Eiea, A.N.Eaieoi?eia, 1982). Aeoeai?noue eaoaeace a
?ioia?e ??aeei? ? ia?ioeaeiiio nae?ao? aecia/aee ca iaoiaeii Aaea ?
Coaeiai? (I.A.A?o?iiaa, 1988). E??i oiai, noai i?ioean?a IIE ioe?ithaaee
iaoiaeii oai?ethi?ianoeaioe?? (I.A.Eocuei?ia ? ni?aaao., 1983).

Aeey oanooaaiiy ooieoe?? a?iio?co, ueoiaeaeii?, iaaeie?eiaeo oa
i?aeoeoieiai? caeic aecia/aee a ne?iaaooe? e?ia? ai?no oe?aio?iiiiai
ai?iiia a?iio?ca (OOA), o?eeiaeoe?iio?ia (O3), oe?ien?ia (O4),
ei?oeciea, ?inoe?ia ?aae?i?ioiieia?/iei iaoiaeii ca aeiiiiiaith
noaiaea?oieo iaai??a ne?iaaoie. ??aaiue OOA aecia/aee ca aeiiiiiaith
iaai?o RIA-mat-TSH o??ie “Aee-Iaeeeie?iaeo”; O3, O4, ei?oecieo oa
?inoe?io ?c canoinoaaiiyi ?aae?i?ioiieia?/ieo iaai??a aeine?aeiiai
ae?iaieoeoaa ?AIO AI Aaea?on?. Aeoeai?noue c?ace?a i?ae?aoiaoaaee ca
aeiiiiiaith aia?aoo “Aaoa-1”.

Caa?? aaiicii? e?ia? aeey ?ioiieia?/ieo, a?io?i?/ieo ?
?aae?i?ioiieia?/ieo aeine?aeaeaiue i?iaiaeeee o an?o oai?eo c?aieo ia
1-2 ? 6-7 aeiae, i?e inoaii??e?o? aeiaeaoeiai ia 12-13 aeiao, a i?e
aino?iio ai?eiiio e?ioaaeai?o? o ae?oae, ye? i?aeiaee ae?? ?ii?coth/iai
aei?ii?ithaaiiy oa o?ii?/iiio ia?ioeo? ua ? /a?ac i?nyoeue a?ae ii/aoeo
caoai?thaaiiy. O ca’yceo c oei, ui a ia??iae ?ai?n?? OII aiaeie?eiiee
noaoon oai?eo ia a?ae??ciyany a?ae eiio?ieueii? a?oie ae?oae, aeai?
?aae?i?ioiieia?/ieo aeine?aeaeaiue ia iaaiaeyoueny.

Ae?aaiinoe/ia oeueo?acaoeiaa ianoaaeaiiy neeiieo caeic cae?enithaaeiny
ca aeiiiiiaith aia?aoo AEIEA SSD-500 c aeei?enoaiiyi e?i?eiiai aeao/eea
7,5 IAoe a ?aaeueiiio ?aaeei?.

?aioaaiieia?/ia aeine?aeaeaiiy ieaeiuei? uaeaie oa i?eaooieo caeic
?iaeee a aeaio i?iaeoe?yo – i?yi?e ? aieia?e (I.A.?aaoo?ia,
I.I.*oi?ei?ia, 1991).

Caaaeueia e?euee?noue i?eaaoieo ? niaoe?aeueieo iaoiae?a aeine?aeaeaiue
neeaea 57195.

Noaoenoe/io ia?iaeo oeeo?iaiai iaoa??aeo i?iaaaeaii ia ia?niiaeuei?e AII
?AI ?N/AO 386 DX/2 ca aeiiiiiaith iaeaoo i?eeeaaeieo i?ia?ai c
aeei?enoaiyi ia?aiao?e/ieo (e?eoa??e Nouethaeaioa) noaoenoe/ieo
iieaciee?a. ?ic?aooiie aeiiii?/ii? aoaeoeaiino? e?eoaaeueieo caoiae?a
i?iaiaeeee ca?aeii aeac?aie A.A.Aieiaoaaaa ? ni?aaao. (1982).

?acoeueoaoe aeanieo aeine?aeaeaiue

Ca aeaieie iaoi? ee?i?ee e?ioaaeai?o, aaeaiioeaaiiia, aino?ee
iaeiioiaaiiee inoaii??e?o o?ea ieaeiuei? uaeaie oa o?ii?/iee
ia?aio?iaoiciee ia?ioeo neeaee 42% a?ae on??? e?eueeino? noaoe?iia?ieo
noiiaoieia?/ieo oai?eo ? 11% a?ae caaaeueii? e?eueeino? ae?oae c
aino?ith o??o?a?/iith iaoieia??th.

I?iaaaeaiee iaie aiae?c aioo??oiueioo?iaiiai ia??iaeo ?icaeoeo aeicaieea
anoaiiaeoe, ui o ianoaaeaieo ae?oae iaoa?? iaee iaoieia?/i? ii?ooaiiy
ia?aa?ao aaa?oiino? a 671 aeiaaeeo (81%) i?ioe 10 (20%) a eiio?ieuei?e
a?oi?. Ii?ooaiiy iieiaiai? ae?yeueiino? niinoa??aaeinue o 234 iaoa??a
(28%) i?ioe 4 (8%) a eiio?ieuei?e a?oi?. Ia a?oaeiiio aeaiaeiaoaaii?
aei ?ieo ciaoiaeeeanue 81 aeeoeia (10%) i?ioe 28 (56%) a a?oi?
caei?iaeo ae?oae. Ae?oe, ye? ciaoiaeeeenue ia ooo/iiio oa ci?oaiiio
aeaiaeiaoaaii? /ano?oa oai??ee i?ioyaii ia?oiai ?ieo aeeooy – 427 (52%),
i?ae ae?oe eiio?ieueii? a?oie – 14 (28%).

Iayai?noue o?ii?/ieo caoai?thaaiue i?aai?a ? nenoai aeyaeaii o 542
ae?oae ?c 830 (65%). Aea/aiiy aiaiiaco caoai?thaaiiy aeicaieeei
anoaiiaeoe, ui aeieeiaiith aino?iai caiaeaiiy oa caaino?aiith OII o 654
ae?oae (79%) ia?aaeoaaa iaoyaeeeaee i?aii?a?aeiee oii.

Aacoiiaii, ui aeuacaaaeai? iani?eyoeea? oaeoi?e a cia/i?e i???
aieeaathoue ia ?aii?e iioiaaiac, i?ecaiaeyoue aei cieaeaiiy
caoenii-aaeaioaoe?eieo iiaeeeainoae aeeoy/iai i?aai?cio oa
noai?ththoue ia?aaeoiiae aeey oi?ioaaiiy o ae?oae iaoieia?/iiai
neiioiiieiiieaeno, yeee iiaea ?aae?coaaoeny iaa?oue i?e i?i?iaeuei?e
ae?? ia oeaieie UEAe iani?eyoeeaeo /eiiee?a.

A a?eueoino? aeiaaee?a aino?? CI UEAe oa caaino?aiiy OII
noi?iaiaeaeoaaeeny iia??oaiiyi caaaeueiiai noaio, oaiia?aoo?iith
?aaeoe??th, yaeuaie ?ioieneeaoe?? oa i?enei?aiiyi OIA. Eaeeioeeoa?iee
?iaeaen ?ioieneeaoe?? caeaaeaa a?ae ee?i?/ieo i?iya?a ? iicieia?/ii?
oi?ie caoai?thaaiiy oa noaiiaea: i?e aino?iio ai?eiiio e?ioaaeai?o?
1,270,09, i?e aino?iio ai?eiiio e?ioaaeai?o? o ii?ii?iaieo ae?oae
1,310,11, aaeaiioeaaiii? – 1,980,22, i?e inoaii??e?o? 2,340,14,
caaino?aii? OII 1,220,08 i?ioe 0,900,06 a eiio?ieuei?e a?oi? ae?oae.

I?e aea/aii? oeeoieia?/ii? ea?oeie ai?eiiai aenoaeaoo ia /an
aini?oae?caoe?? i?e an?o oi?iao aino?i? iaoieia?? a i?aia?aoao
aecia/aeanue cia/ia e?euee?noue aeao?eoo, a?eo?ioeeo?a, aeano?oeiaaieo
iaeo?io?e?a, iiiaeeiieeo e?ioioeeo?a.

A ia?ioeaeiiio nae?ao?, io?eiaiiio a ia??iae caaino?aiiy, aeyaeyeeny
/enaeuei? neiie/aiiy iaeo?io?e?a, cia/ia /anoeia yeeo aoea c
ii?oieia?/iieie iciaeaie aeano?oeoe??, e?ioi?aei? ee?oeie, aiceiio?ee,
iiiaeeiie? iiiioeeoe, ?ieiee cono??/aeeny ee?oeie oeee?iae?e/iiai ?
ieineiai ai?oae?y. A ia??iae ?ai?n?? OII, ia aeeaey/enue ia
a?aenooi?noue ee?i?/ieo i?iya?a caoai?thaaiiy, a i?aia?aoao anoaiiaeaia
iayai?noue ?ic??ciaieo a?oi iaeo?io?e?a, iiiaeeiie? e?ioioeeoe ?
ai?oae?aeuei? ee?oeie.

Oeueo?acaoeiaa ianoaaeaiiy, yea i?iaiaeeeiny ae?oyi c eieae?caoe??th
caiaeueiiai i?ioeano a i?eaooii-aeoaaeuei?e ae?eyioe? c iaoith
aeeoa?aioe?aeueii? ae?aaiinoeee ? ooi/iaiiy ae?aaiico, aeicaieeei
anoaiiaeoe i?e e?ioaaeai?o? iayai?noue a?iiaoiaaiieo ooai?aiue (a?ae 1
aei 4) iai?aeii? oi?ie, ??cieo ?ici???a, c /?oeeie eiioo?aie, ioi/aieo
aoiou?eueiaiith oeaieiith caeice.

I?e OII eainoea aeaeyaeaea ou?eueiaiith, a naia caeica iaea
iaiaeii??aeio no?oeoo?o ca ?aooiie i?enooiino? a ia?aio?i?
a?iiaoiaaiieo ae?eyiie (n?aeaeoac?a) ?ici??aie a?ae 1 aei 4 ii a
ae?aiao??, iaaeiei yeeo ?icoaoiaoaaeeny ?? aoiou?eueiai? oeaieie.

Aea/aiiy aeaeiaiai neeaaeo i?e?iaii? oei?e ai?eieo ina?aaee?a ? nae?aoo
o?aaeaieo caeic a ia??iae caaino?aiiy OII anoaiiaeei i?aaaethaaiiy
cieioenoeo noao?eieie?a (Staph. aureus), ai?aea?iaeueieo noao?eieie?a
(Staph. epidermidis) oa aaiie?oe/ieo no?aioieie?a (Str. haemoliticus),
ye? aieiae?ee ae?aaeaiith a?ieia?/iith aeoeai?noth.A iacia/i?e
e?eueeino? aeiaaee?a eieia? ooaie ooai?thaaee anioe?aoe?? c ?ioeie
i?e?ii?aai?ciaie. Ieaciieiaaoethth/? noao?eieiee a?aeiineeenue, a
iniiaiiio, aei 2 ? 3 oaaia?oi, a no?aioieiee aei na?ieia?/ieo a?oi A,
B, D. ?o e?euee?noue noaiiaeea 107 – 109.

I?e aino?iio ai?eiiio e?ioaaeai?o? o ae?oae, ye? i?aeiaee ae??
?ii?coth/iai aei?ii?ithaaiiy, oa i?e OII a oac? ?ai?n?? ca?eueooaaeanue
ieoiia aaaa ai?aea?iaeueieo noao?eieie?a (Staph. epidermidis) oa
iaaaiie?oe/ieo no?aioieie?a (Str. anhaemoliticus) c iii??iith oa
neaaeith oa?iaioaoeaiith aeoeai?noth. C?inoaea e?euee?noue aeiaaee?a
aeae?eaiiy anioe?aio?a, ui aeacoaaei ia ii?ooaiiy a aeinenoai?
i?e?ia?ioeeiico. ?o e?euee?noue aoea cia/ii iaioith – 105 – 107 .

Caa?oa? ia naaa oaaao oaeo iie?aioea?ioeei?acenoaioiino? aeae?eaieo
i?e?ia?a, iniaeeai aei aioea?ioee?a ia?oiai iieie?iiy, caoa aiie
i?iyaeyee ae?aaeaio /ooeea?noue aei oeaoaeinii?ei?a, aaioai?oeeio ?
e?ieii?oeeio.

sse iieacaee ?acoeueoaoe iaoeo aeine?aeaeaiue, CI UEAe, ye? aea/aeeny a
aeai?e ?iaio?, iathoue ?yae caaaeueieo aeaiaio?a iaoiaaiaco ?
noi?iaiaeaeothoueny aiiieia?/ieie ci?iaie iieaciee?a ianiaoeeo?/ii?
?acenoaioiino? i?aai?cio, ia?aeeniiai ieeneaiiy e?i?ae?a ?
ai?iiiaeueiiai aaeaino. Oaeee ca’ycie i?ae aeacaieie nenoaiaie
yaey?oueny caeiiii??iei, oiio ui ?o aca?iia?aeiineie caaacia/othoue
aaeaeaaoia ? iiaiioe?iia ?aaaoaaiiy i?aai?cio ia ethaee iioeiaeaeoth/ee
oaeoi?, a oiio /ene? caiaeaiiy ? ?ii?coth/a aei?ii?ithaaiiy.

Eiaa?aioieie eaioethaaie i?ae oeeie nenoaiaie iiaeooue aenooiaoe ee?oeie
e?ia?: iiiioeeoe, e?ioioeeoe, iie?ii?oiiyaea?i? eaeeioeeoe, aiaeiaaii?
?ioiiiiaeoeyoi?e (N.A.Eaoeeinueeee ? ni?aaao., 1992; ?.I.Eaeaeaoaa,
1995).

An? caiaeuei? caoai?thaaiiy noi?iaiaeaeoaaeeny iaeiioeiieie ci?iaie
iieaciee?a ?ioiii? nenoaie (oaae. 1): cieaeaiiy a?aenioeo O-ee?oei
(A-?OE) ia oii? ca?eueoaiiy a?aenioeo A-ee?oei (I-?OE), ciaioaiiyi
?ioii?aaoeyoi?iiai eiao?oe??ioo (O-oaeia?e/O-noi?ani?e) ca ?aooiie
ia?aaaaeiiai cieaeaiiy oaio?e?i?acenoaioieo O-ee?oei ? ca?eueoaiiy
oaio?e?i/ooeeaeo. Ia aeeeth/aii, ui ii?ooaiiy ni?aa?aeiioaiiy
?ioii?aaoeyoi?ieo iiioeyoe?e O-e?ioioeeo?a a?ae?a?a? i?ia?aeio ?ieue a
?icaeoeo aeen?ioiiaeiaoe?iai?? ? oi?ioaaiiy aoi?eiii? ?ioiii?
iaaeinoaoiino?.

A e?oa?aoo?? inoaii?o ?ie?a iieacaii, ui i?ney ae?? iaeeo aeic
?aae?aoe?? o?eaaeee /an niinoa??aathoueny ii?ooaiiy ?ioiii? nenoaie ? a
?yae? aeiaaee?a aiie ia?aoiaeyoue a iiao ye?noue (N.A.Eii?na?aiei ?
ni?aaao., 1994). I?e oeueiio a?aeaoaathoueny no?oeoo?i? ci?ie a
noaiiioeyoe?yo O-ee?oei, cieaeo?oueny e?euee?noue i?e?iaeieo e?ea??a, ui
iiaea aecia/aoe i?aeaeuaio /ooeea?noue aei aaeoa??aeueieo ? i?ioicieieo
?ioaeoe?e.

Ae?enii, iaie a a?oi? ae?oae c aino?ei ai?eiei e?ioaaeai?oii, ye?
i?aeiaee ae?? ?ii?coth/iai aei?ii?ithaaiiy, aeyaeaii cia/iee aeenaaeain
o ni?aa?aeiioaii? O-oaeia??a ? O-noi?ani??a ca ?aooiie ciaioaiiy aeie?
ia?oeo oa i?aeaeuaiiy inoaii?o, cieaeaiiy e?eueeino? A-e?ioioeeo?a,
?ioiiaeiaoe?i?a A ? G, ui aeaco? ia iaaaeaeaaoi?noue ?ioiii?
a?aeiia?ae? i?aai?cio ia caiaeaiiy o oe??? eaoaai??? oai?eo.

Ne?ae caoaaaeeoe, ui i?e an?o iicieia?/ieo oi?iao caiaeueieo i?ioean?a
UEAe niinoa??aaeinue i?eai?/aiiy ?ioiieia?/iiai ?aca?ao ?ioiai? ??aeeie
(oaae. 1), a i?e OII ? ia?ioeaeiiai nae?aoo – ciaiooaaeanue
eiioeaio?aoe?y S Ig A (8,921,42 i?ioe 15,071,27), cieaeoaaeanue
aaeoa?eoeeaeia aeoeai?noue e?cioeeio (156,3415,51 i?ioe 224,4917,27).

A iaoeo aeine?aeaeaiiyo aoea a?aenooiy /?oea caeaaei?noue i?ae
eiioeaio?aoe??th Ig A a ne?iaaooe? e?ia? ? S Ig A a ?ioia?e ??aeei? oa
ia?ioeaeiiio

nae?ao?. I?e aino?iio ai?eiiio e?ioaaeai?o? o ae?oae ?c cii,
caa?oaeiaieo ?aae?iioee?aeaie ? inoaii??e?o? S Ig A cieaeoaaany ?acii c
Ig A, a i?e e?ioaaeai?o?, aaeaiioeaaiii? ? OII a noaae?? caaino?aiiy
niinoa??aaeinue cieaeaiiy S Ig A ia oii? i?aeaeuaiiy Ig A a ne?iaaooe?
e?ia?. A oac? ?ai?n?? OII iaei i?noea cieaeaiiy S Ig A eeoa a
ia?ioeaeiiio nae?ao?.

I?iaaaeaiee noaoenoe/iee nenoaiiee aiae?c aeicaieea anoaiiaeoe, ui oaea
ni?aa?aeiioaiiy ci?i eiioeaio?aoe?? S Ig A ? Ig A aecia/a?oueny
i?aeaeuaiiyi ei?oecieo. Ci?ie ae ??ai?a ?ioeo ai?iii?a (OOA, O3, O4,
?inoe?io) iathoue iacia/iee aieea ia oeth nenoaio.

A?aoiaoth/e aaaeeeaee iaoiaaiaoe/iee ca’ycie i?ae caiaeaiiyi,
i?ioeanaie ?ioi?oaoo ? noaiii ia?aeeniiai ieeneaiiy e?i?ae?a
(Ae.I.Iayinueeee, 1991; N.Eiai ? ni?aaao., 1983), ie aea/eee noai
a?eueii?aaeeeaeueiiai ieeneaiiy a e?ia?, ?ioia?e ??aeei? ? ia?ioeaeiiio
nae?ao? (oaae. 2, 3, 4).

Caa?oa? ia naaa oaaao oie oaeo, ui ?icaeoie an?o aino?eo CI UEAe ia
/an aini?oae?caoe?? oa caaino?aiiy OII noi?iaiaeaeo?oueny iineeaiiyi
a?ioai?ethi?ianoeaioe?? e?ia?, i?aeaeuaiiyi ??aiy ae??iiaeo eii’thaao,
niiioaiiiai aaiie?co a?eo?ioeeo?a, c?inoaiiyi iaeiie/aiiy IAeA a ?o
iaia?aiao, i?aeaeuaiiyi aeoeaiino? NIAe oa oea?oeiieaci?io ia oii?
cieaeaiiy eaoaeace. Iiae?ai? ci?ie aoee aeyaeai? a ?ioia?e ??aeei? ?
ia?ioeaeiiio nae?ao?. Ie iiai?noth iiae?ey?ii oi/eo ci?o A.?.Ieo/aiea
(1996) a?aeiinii oiai, ui i?aeaeuaiee neioac oea?oeiieaci?io ? NIAe
iineoue oa?aeoa? aaeaioeaiiai, a cieaeaiiy aeoeaiino? eaoaeace aeaco? ia
iacia/i? eiiiainaoi?i? iiaeeeaino? nenoaie AIC o ae?oae.

O ae?oae c aino?ei ai?eiei e?ioaaeai?oii, ye? i?iaeeaaee ia ?aae?aoe?eii
caa?oaeiaieo oa?eoi??yo, ci?ie aoee o??? ae iai?aaeaiino?, ca
aeeeth/aiiyi cieaeaiiy aeoeaiino? NIAe ? iaci?iiino? ??aiy
oea?oeiieaci?io, iaeiiai c aieiaieo aioeieneaeaio?a ne?iaaoee e?ia?.
Oae? ?acoeueoaoe cana?ae/othoue i?i iaae?iiy aioeieneaeaioiiai caoenoo
ia caaaeueiiio oa i?noeaaiio ??aiyo ? ?icaeoie “neiae?iio
ia?ieneaeaoe??” (A.I.Aiae?ueia, 1990; O.I.Aeaayoe?ia, 1990).

Ca iaoei ia?aeiiaiiyi, aeoeaaoe?y i?ioean?a IIE a aeaieo aeiaaeeao,
yaey?oueny neeaaeiaei eiiiiiaioii neiae?iio aaeaioaoe??. Aeano?oeoe?y
a?iiaia?ai, yea aeieea? a ?acoeueoao? caiaeaiiy ca ?aooiie eiai
aeueoa?aoeaieo /eiiee?a oa iia?aoeaia ao?o/aiiy iaoiiaeththoue
noeioeyoe?th ?ie?aoe?? ei?oecieo, aeoea?coth/e oei naiei ianiaoeeo?/i?
iaoai?cie aiioe?iiaeueii-aieueiaiai no?ano.

Aeine?aeaeaiiyie anoaiiaeaii, ui ?ioaineo?eaoe?y IIE ? i?eai?/aiiy AIC
a on?o a?oiao oai?eo ciaoiaeyoueny a i?yi?e caeaaeiino? a?ae iayaiino?
noiooi?o caoai?thaaiue, ?iciianthaeaeaiiy caiaeueiiai i?ioeano ?

iiyae oneeaaeiaiue. Oa?aeoa?iei ? oa, ui aeoeaaoe?y IIE i?aeaeuo?oueny
i?iii?oe?eii cieaeaiith oa?iaioaoeaiiai eaioethaa AIC.

A ia??iae ?ai?n?? OII niinoa??aaeanue oaiaeaioe?y aei iie?auaiiy
iieaciee?a IIE ? AIC, iaeiae aeoeai?noue eaoaeace caeeoaeanue iecueeith,
iniaeeai a ?ioia?e ??aeei? ? ia?ioeaeiiio nae?ao?. Inoaii? na?ae/eoue
i?i iaiao?aei?noue i?iaaaeaiiy ?aaa?e?oaoe?eii? oa?ai?? a oeae ia??iae
caoai?thaaiiy.

Oaaeeoey 4. A?io?i?/i? iieacieee ia?ioeaeiiai nae?aoo i?e OII

o ae?oae a aeeiai?oe? e?eoaaiiy

Ia??iae ia?aa?ao OII oa iaoiae e?eoaaiiyCaaino?aiiy?ai?n?y?
i/iIieacieeI?ae-oe/ii caei?i-a?Aei e?eo-aaiiyI?ney o?aaee-oe?eiiai
e?eo-aaiiyI?ney cai?i-iiii-aaiiai e?eo-aaiiyAei e?eo-aaiiyI?ney
o?aaee-oe?eiiai e?eo-aaiiyI?ney cai?i-iiii-aaiiai
e?eo-aaiiy1.Na?oeinoia, ?ii/nae1720342726107356*20625
389*20314362*21017348*18689 352*18174 3642. ?ioaineai?noue na?/aiiy,
?ii/nae1468

1212279 134*1934 1251638 1321987 132*1635 1281487 1243.IAeA, ii/aoeiaee
??aaiue, ieiieue/e1,44 0,136,12 0,18*4,76 0,15*1,96 0,422,54 0,24*1,63
0,191,28 0,314.IAeA, i?ney 1,5 aiae. ?ieo-aaoe??,ieiieue/e1,72
0,1510,670,29*7,65 0,21*2,78 0,24*4,18 0,32*2,42 0,21*1,77 0,225.I?e??no
IAeA, %38,7173,3460,7141,8364,5748,4738,286. NIAe, IAe-0,03 0,01-0,23
0,04*-0,17 0,04*-0,03 0,02-0,03 0,02-0,03 0,02-0,03 0,017. Eaoaeaca,
IAe1,23 0,110,72 0,12*0,940, 10*1,08 0,120,92 0,10*0,96 0,09*1,27 0,11

I?e ??cieo caiaeueieo oa ?ioaeoe?eieo caoai?thaaiiyo o ae?oae /ooeeai
?aaao? a?iioaeaii-a?iio?ca?ia nenoaia, i?e/iio oey ?aaeoe?y iia’ycaia c?
ci?iaie noaio ?ioiii? nenoaie (A.A.Oii?i ? ni?aaao., 1991). Oaea
neia?a?/ia ae?y aeinyaa?oueny oeyoii i?yiiai aieeao ai?iii?a ia
iieacieee ?ioiii? nenoaie, /a?ac ai?iiie oeiona, oeyoii aeei?enoaiiy
caaaeueieo iaae?aoi??a (?.I.Eaeaeaoaa, 1995; I.E.Blalock,1994).

Iaie aoea aea/aia eiioeaio?aoe?y OOA, O3, O4, ei?oecieo ? ?inoe?io
(oaae. 5). Aeey aino?iai e?ioaaeai?oo ? aaeaiioeaaiiie oeiiaei yaeyeinue
cieaeaiiy eiioeaio?aoe?? O3. A?aenooi?noue aaeaeaaoiiai i?aeaeuaiiy
iaoaaie?/ii-aeoeaiiai ai?iiia O3 i?e aino?iio caiaeaii? e?ioaoe/ieo
aoce?a o ii?ii?iaieo ae?oae iiaea neoaeeoe iciaeith cieaeaiiy
ooieoe?iiaeueieo iiaeeeainoae oe?ai?aeii? nenoaie o oe??? eaoaai???
oai?eo. Cieaeaiiy ae ??aiy O4, a??ia?aeii, iia’ycaia c i?aeaeuaiith
iio?aaith eiai i?aai?ciii a oiiaao aieeao ?ii?coth/iai aei?ii?ithaaiiy
oa caiaeaiiy.

A.A.Ai?y/eo ? ni?aaao. (1995) aaaaeathoue, ui cieaeaiiy O3 aeieea?
aiane?aeie noi?an?? ooieoe?? ueoiaeaeii? caeice ca ?aooiie i?aeaeuaiiy
eiioeaio?aoe?? ei?oecieo. Iaeiae, ie ia iiaeaii iiai?noth iiaiaeeoenue
c oe??th aeoieith, oiio ui i?e aeayeeo aeaeao iaoieia??, cie?aia
aino?iio ai?eiiio e?ioaaeai?o?, ie ?a?no?oaaee iacia/ia ca?eueoaiiy
??aiy ei?oecieo, oi/ eiioeaio?aoe?y O3 aoea cia/ii cieaeaia.
Ia?aeii?noue ii?ooaiiy ooieoe?? ueoiaeaeii? caeice i?aeoaa?aeaeo?oueny
a?aenooi?noth cia/ieo ci?i ??aiy OOA i?e e?ioaaeai?o? oa aaeaiioeaaiii?.

I?e inoaii??e?o? o?ea ieaeiuei? uaeaie ci?ie eiioeaio?aoe?? ai?iii?a
aoee iaea?eueo ae?aaeai?: i?aeaeuoaaany ai?no a e?ia? OOA ? ei?oecieo,
cieaeaany – O3 ? ?inoe?io. Cieaeaiiy ?inoe?io i?e i?aeaeuaii? ei?oecieo
iiaea cana?ae/oaaoe i?i aeniaaeaiiy eiai i?iaeoeoe?? aeey eiiiainaoe??
aoaeaaiaeiiai iai?io. E??i oiai ?inoe?i aieiae?? ae?aaeaiith aeoeai?noth
?inoeiaiai oaeoi?o ? a oiiaao ianeaii? aeano?oeoe?? e?noee oa ioi/oth/eo
i’yeeo oeaiei iiaea i?aeaeuoaaoenue eiai iio?aaa aeey ?aia?aoeaii?
?aaaia?aoe??.

Iaoiaiiiii?/iith iniaeea?noth e?ioaaeai?oo o ae?oae ?c cii caa?oaeiaieo
?aae?iioee?aeaie, aoei aeiaaio?eaaea i?aeaeuaiiy ??aiy ei?oecieo, ui
iiaei a?aeia?aaeaoe aenieo iai?oaeai?noue aaeaioeaieo i?ioean?a a
ii??aiyii? c ae?oueie ?c /enoeo ?aa?ii?a (I.A.Na?a??a ? ni?aaao., 1998).
Iiae?aia yaeua ie oaeiae niinoa??aaee i?e aaeaiioeaaiii? ? inoaii??e?o?.

I?e caaino?aii? OII ?icaeaathoueny aiaeie?eii? ii?ooaiiy, ye?
i?iyaeythoueny ci?iaie a ooieoe?thaaii? a?iio?ca?ii-oe?ai?aeii? nenoaie,
iaoiiaeaieie ii?ooaiiyi iaoai?ci?a cai?ioiueiai ca’yceo ?, a??ia?aeii,
cieaeaiiyi /ooeeaino? ?aoeaioi?iiai aia?aoo ueoiaeaeii? caeice.

Cieaeaiiy iieaciee?a ee?oeiii? ? aoii?aeueii? eaiie ?ioi?oaoo i?e
aino?eo ai?eieo i?ioeanao UEAe iiaeia iiynieoe aeenooieoe?iiaeueieie
ii?ooaiiyie a ?iaio? a?iio?ca?ii-oe?ai?aeii? nenoaie. I?aeaeuaiiy
??aiy OOA aeceaa? cieaeaiiy caaaeueii? e?eueeino? O-e?ioioeeo?a,
cieaeaiiy ae ??aiy O3 i?ecaiaeeoue aei i?eai?/aiiy aeoeaiino? A-nenoaie
?ioi?oaoo ?, caeiiii??ii, ae?iaee aeayeeo aioeo?e, ui aeaco? ia
ae?aaeaio aca?ii?aaoeyoe?th ?ioiii? ? iae?iaiaeie?eiii? nenoai.

Ocaaaeueithth/e io?eiai? ?acoeueoaoe, ie noai?eee a?iioaoe/io noaio
ao?iiaoiaaiaco aino?eo caiaeueieo caoai?thaaiue uaeaiii-eeoeaai?
ae?eyiee oa caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o ae?oae
(?en. 1).

Ii?ooaiiy, ye? aeieeathoue a i?aai?ci? aaa?oii? i?ae aieeaii
iani?eyoeeaeo aeci- ? aiaeiaaiieo /eiiee?a, iiaeooue i?ecaiaeeoe aei
iioeiaeaeaiiy AeIE ? iiyae niaaeeiaeo ci?i o iiaiia?iaeaeaiiai
(A.I.Aeeeueiai, 1987). Iaeiie/aiiy iaaooeo o iinoiaoaeueiiio ia??iae?
noeeueieo oaeoi??a i?ecaiaeeoue aei cieaeaiiy caoenii-aaeaioaoe?eieo
iiaeeeainoae i?aai?cio aeeoeie oa ni?ey? ?iceaaeo i?e?ia?ioeaiico. Ca
oeeo oiia aeoea?caoe?y aooii?e?ioei?e iineeth? ?ecee aeieeiaiiy aino?iai
caiaeai-

iy /e caaino?aiiy o?ii?/ieo caoai?thaaiue uaeaiii-eeoeaai? ae?eyiee, yea
i?aeeyaa? cia/iiio aioeaaiiiio iaaaioaaeaiith. O aeiaaeeo ?o ?icaeoeo
niinoa??aa?oueny iiaeeo?eaoe?y no?oeoo?e oa ooieoe?? aaaaoueio i?aai?a ?
nenoai (cieaeaiiy ?ioiieia?/iiai iioaioe?aeo i?aai?cio, iineeaiiy
i?ioean?a a?eueii?aaeeeaeueiiai ieeneaiiy, iaae?iiy ??aiy
aioeieneaeaioiiai caoenoo, ii?ooaiiy iae?i-aiaeie?eiii? ?aaoeyoe??).

Aeoiaey/e ?c anoaiiaeaieo i?ia?aeieo neeaaeiaeo eiiiiiaio?a
iaoiaaiaco, ye? aa?ooue o/anoue a ia?aa?c? aino?eo CI UEAe ? OII iaie
aeae?eai? aieiai? i?eioeeie iaoiaaiaoe/iiai e?eoaaiiy:

· naiaoe?y aiaieua caiaeaiiy;

· naeaeoeaia aioeaaeoa??aeueia oa?ai?y;

· aeei?enoaiiy ?ioiiei?aeoi??a;

· aeei?enoaiiy aioeieneaeaio?a;

· aeei?enoaiiy aaeaioiaai?a.

Aiae?c ?acoeueoao?a ee?i?ei-eaai?aoi?ieo aeine?aeaeaiue, i?iaaaeaiee o
oai?eo, ye? io?eioaaee o?aaeeoe?eia e?eoaaiiy (aioea?ioeee,
noeueoai?eai?aee, a?iinainea?e?coth/? i?aia?aoe, a?oai?iioa?ai?y, OA* ia
aiaieua caiaeaiiy, ioeea?iao iao??y i?e i?iaaaeaii? i?io?eaeoe/ieo
caoiae?a o oai?eo ia OII), aeicaieea anoaiiaeoe eiai iaaeioe?euei?noue,
ui niiioeaei ian aei ?ic?iaee noai eiiieaeniiai aeeoa?aioe?eiaaiiai
e?eoaaiiy a i?neyiia?aoe?eiiio ia??iae? aeey eiaeii? iicieia?/ii? oi?ie
caoai?thaaiiy:

· aino?ee ai?eiee e?ioaaeai?o: oeiae?i N5, oieioa?ie-aoeaoao,
anei?ooei, ae?acie?i i?ioyaii ia??iaeo noaoe?iia?iiai e?eoaaiiy;

· aino?ee ai?eiee e?ioaaeai?o o ae?oae, ye? i?aeiaee ae?? ?ii?coth/iai
aei?ii?ithaaiiy: oeiae?i N7, ia?ae?ioaoe/ia aaaaeaiiy aioea?ioee?a,
oieioa?ie-aoeaoao, anei?ooei, ae?aacie i?ioyaii ia??iaeo
noaoe?iia?iiai e?eoaaiiy ? ua ai?iaeiaae 21 aeiae i?ney aeienee,
ae?acie?i i?ioyaii 7 ae?a;

· aaeaiioeaaiiia: oeiae?i N7, ia?ae?ioaoe/ia aaaaeaiiy aioea?ioee?a,
oieioa?ie-aoeaoao, anei?ooei (a iiaeai?i?e aeic?), ae?acie?i i?ioyaii
noaoe?iia?iiai e?eoaaiiy.

E??i oiai, an?i ae?oyi oeeo a?oi i?ioyaii ia?oeo o?ueio ae?a i?ney
iia?aoeaiiai ao?o/aiiy i?iaiaeeee naiaoe?th ?aiiaiai oiaeo ? ii?iaeieie
ai?eieea 1% ?ic/eiii e?cioeeio, /a?ac 30 oaeeei a ?aiiaee o?ae aaiaeeee
5% ?ic/ei oi?o?ieo, ae?aioaaee eiai, ia ?aio iaeeaaeaee oeaieiiee
aoaeaoeaaee ni?aaio AOO-I. Oai?ei, c eieae?caoe??th caiaeueiiai i?ioeano
a i?eaooii-aeoaaeuei?e ae?eyioe?, aeiaeaoeiai i?iaiaeeee ?inoeeyoe?th a
i?ioieiao nenoaio 1% ?ic/eio e?cioeeio. Ii/eiath/e c 2 aeiae
canoiniaoaaee eaca?ioa?ai?th ii aeoioieoo?i?e iaoiaeeoe? a ?aaeei? 5-25
iAo/ni2, aeniiceoe?y 1-2 oaeeeie N7, i?ecia/aee ianaae eii??oeaai?
ciie, e?eoaaeueio a?iianoeeo o?e?aciaa i?ioaiiy ii?iaeieie ?ioa 1%
?ic/eiii e?cioeeio. I?ney iaeeaaeaiiy ia?aeiii-a?aeno?i/aieo oa?a (4-5
aeiaa) ia ?aio ?iaeee aie?eaoe?? c a?iicieai AI.

· aino?ee iaeiioiaaiiee inoaii??e?o o?ea ieaeiuei? uaeaie:

Ia?o? o?e aeiae an?i ae?oyi i?iaiaeeeanue ?iooc?eia oa?ai?y (10% ?ic/ei
aetheice, ?ic/ei ??iaa?a, ?inoe?i ii 1 IAe ia 4 a?aie aetheice, ?ic/ei
anei?a?iiai? eeneioe, 7,5% oei?enoee eae?e). Aioo??oiueii’yciai
aaiaeeee oeaoaeinii?eie ia?oi? aaia?aoe?? o?e/? ia aeiao i?ioyaii 7-10
ae?a, oeiae?i N10, oieioa?ie-aoeaoao, i?eia?o, ae?aacie, ae?acie?i –
i?ioyaii /ano ia?aaoaaiiy ia noaoe?iia?iiio e?eoaaii?.

A ?aiiaee o?ae i?ioyaii 5 ae?a aaiaeeany aioea?ioee (e?ieii?oeei) oa 5%
?ic/ei oi?o?ieo. Ii/eiath/e c ae?oai? aeiae i?ecia/aee eaca?ioa?ai?th ii
neaioth/?e iaoiaeeoe? a ?aaeei? 25 iAo/ni2, aeniiceoe?y 5-10 oaeeei
i?ioyaii 12 ae?a. I?ney i?ioeaaeo?e iaeeaee iia’yceo c i?oaoeeaeii, a
i?e ia?aoiae? ?aiiaiai i?ioeano a 2 oaco c a?iicieai AI. Uiaeaiii, ii
5-6 ?ac?a ia aeiao, i?iaiaeeee i?ioaiiy ii?iaeieie ?ioa ?ic/eiaie 1%
e?cioeeio ? o?e/? — 5% oi?o?ieo. E?eoaaeueia o?ceoeueoo?a aeeth/aea
niaoe?aeuei? ai?aae aeey aeoaaeueieo ? i?i?/ieo i’yc?a.

· OII a oac? caaino?aiiy: oeiae?i N3, oieioa?ie-aoeaoao, anei?ooei,
ae?acie?i i?ioyaii 7 ae?a, o?ueio?aciaa ?inoeeyoe?y a i?ioieiao
nenoaio caeice 1% ?ic/eio e?cioeeio, c iine?aeoth/ei ui?aciaei
ianoaaiiyi ?? ? aaaaeaiiyi i?ney oeueiai 5% ?ic/eio oi?o?ieo, i?ioaiiy
ii?iaeieie ?ioa 1% ?ic/eiii e?cioeeio i’youe ?ac?a ia aeaiue,
aae?e-iaiiiaa ii?ii?ithaaiiy ae?eyiee ?icoaooaaiiy caeice ii
aeoioieoo?i?e iaoiaeeoe? a ?aaeei? 5-15 iAo/ni2, aeniiceoe?y 1-2 oaeeeie
N7, iia’ycee c aeeiaeneaeii oa ?iaeiiaoaoeeiiaith iaccth, eaaeee ianaae
caeic 3-4 ?ace ia aeaiue aei ? i?ney ?aee.

· OII a oac? ?ai?n??: oieioa?ie-aoeaoao, anei?ooei, ae?aacie i?ioyaii
21 aeiae, naiaoe?y i?ioieiai? nenoaie caeice ?ic/eiaie 1% e?cioeeio ? 5%
oi?o?ieo i?ioyaii 3-o ae?a c ianooiiei aaaaeaiiyi ia 4 aeiao ie??
iae?ieoe (4 ?ace c ?ioa?aaeii a 5 aei?a), i?ioaiiy ii?iaeieie ?ioa 1%
?ic/eiii e?cioeeio aei ? i?ney ?aee, ia iaeanoue caeice —
?icoieoniaaiee io/ie eaca?a a ?aaeei? 1 iAo/ni2, aeniiceoe?y 2 oaeeeie
N10 (iaoaio Oe?a?ie ? 24547A). I?ioe?aoeeaeeai? caoiaee aeeiioaaeeny
aea?/? ia ??e — aaniith oa ainaie.

Aeicoaaiiy an?o i?aia?ao?a i?iaiaeeeiny c a?aooaaiiyi a?eo oa aaae
oai?eo ae?oae: aioea?ioeee oeaoaeinii?eiiaiai ?yaeo ia?oi? aaia?aoe??
aeey aioo??oiueii’yciaiai aaaaeaiiy – 50-100 ia/ea; aioea?ioeee aeey
ia?ae?ioaoe/iiai aaaaeaiiy – ?aciaa aeica neeaaea? 1/4 aeiaiai? aeice
(aeiaiaa aeica aaioai?oeeio – 3-5 ia/ea, e?ieii?oeeio – 10-20 ia/ea);
oeiae?i 1-5 ia ia aeiao; oieioa?ie-aoeaoao – 5-10 ia ia aeiao; anei?ooei
0,025 – 0,1 a ia aeiao; ae?acie?i 0,02 – 0,15 a ia aeiao; ae?aacie (aei
1 ?ieo – 0,001 a ia aeiao; 1-3 ?iee – 0,002 a; 4-8 – 0,003 a; 9-12 –
0,004 a; noa?oa 12 ?ie?a – 0,005 a ia aeiao); i?eia?o (ae?oyi ynaeueiiai
a?eo ii 2 ianoeeee ia aeiao, aeioe?eueiiai – ii 4, oe?eueiiai – ii 7).

C iaoith anoaiiaeaiiy aoaeoeaiino? cai?iiiiiaaieo iaie e?eoaaeueieo
eiiieaen?a aoei i?iaaaeaii ii??aiyeueiee aiae?c ?acoeueoao?a, io?eiaieo
a?ae ?o canoinoaaiiy, c o?aaeeoe?eiei e?eoaaiiyi (oaae. 1-5).

Ia ia??iae ee?i?/iiai iaeoaeaiiy oai?eo c aino?ei ai?eiei e?ioaaeai?oii,
ye? io?eioaaee o?aaeeoe?eia e?eoaaiiy, e?euee?noue O-oaeia??a a e?ia?
caeeoaeanue iecueeith, a ??aaiue Ig G aenieei. A?aei?/aeanue aeayea
noaa?e?caoe?y i?ioean?a ieenethaaeueiiai iaoaaie?cio, iaeiae iieacieee
oai?ethi?ianoeaioe??, NAA, i?e??no IAeA, aeoeai?noue NIAe caeeoaeeny
i?aeaeuaieie. Iie?auoaaany ai?iiiaeueiee noaoon.

A ?ioia?e ??aeei? ia oeae /an ??aaiue S Ig A ? aaeoa?eoeeaeia
aeoeai?noue e?cioeeio iaee oaiaeaioe?th aei i?aeaeuaiiy, i?e??no IAeA
aoa iaeaea oaeei, ye ? ia iiiaio aini?oae?caoe??.

Canoinoaaiiy ?ic?iaeaiiai iaie e?eoaaeueiiai eiiieaeno aeicaieeei
iiai?noth ii?iae?coaaoe ia 6-7 aeiao niinoa?aaeaiiy ?ioiieia?/i?,
a?io?i?/i?, ai?iiiaeuei? iieacieee ye a e?ia?, oae ? a ?ioia?e ??aeei?.

O ae?oae c aino?ei ai?eiei e?ioaaeai?oii, ye? i?aeiaee ae??
?ii?coth/iai aei?ii?ithaaiiy ? io?eioaaee neiioiiaoe/ia e?eoaaiiy, ia
/an e?ea?aeaoe?? aino?eo yaeu caiaeaiiy e?euee?noue O-e?ioioeeo?a,
O-oaeia??a, ??ai? Ig A ? G a e?ia? caeeoeeeny iecueeeie, a e?euee?noue
O-noi?ani??a aenieith. Iieacieee A?I, AIC ? ai?iiiaeueiiai noaoono
iacia/ii iie?auoaaeeny.

A ?ioia?e ??aeei? ??aaiue S Ig A ? aaeoa?eoeeaeia aeoeai?noue
e?cioeeio iacia/ii i?aeaeuoaaeenue, a?aeaoaaeinue iie?auaiiy i?ioean?a
ieenethaaeueiiai iaoaaie?cio.

I?e ianoaaeaii? /a?ac i?nyoeue i?ney iia?aoeaiiai ao?o/aiiy
e?euee?noue O-noi?ani??a caeeoeeany aenieith,a ??ai? Ig A ? G iecueeeie.
Caa??aaeinue oaeiae i?aeaeuaiiy iieaciee?a oai?ethi?ianoeaioe?? ? IAeA
i?ney ?ieoaaoe?? oa cieaeaiiy aeoeaiino? eaoaeace. ??ai? ai?iii?a
noaa?e?coaaeeny.

A ?ioia?e ??aeei? S Ig A ? aaeoa?eoeeaeia aeoeai?noue e?cioeeio
caeeoaeeny iecueeeie, a iieacieee oai?ethi?ianoeaioe?? ? OAE-?aaaoth/eo
i?iaeoeo?a aenieeie.

I?e canoinoaaii? cai?iiiiiaaiiai iaie e?eoaaiiy aaea aei 6-7 aeiae
a?aeaoaaeanue ii?iae?caoe?y a?eueoino? iieaciee?a ?ioi?oaoo a e?ia?, aea
e?euee?noue O-noi?ani??a caeeoeeanue aenieith, a ??aaiue Ig G iecueeei.
Iieacieee oai?ethi?ianoeaioe?? oa OAE-?aaaoth/eo i?iaeoeo?a oaeiae
a??ia?aeii ia?aaeuoaaee na?aaeiueinoaoenoe/i? iieacieee caei?iaeo
ae?oae, ye ? ??aaiue ei?oecieo.

A ?ioia?e ??aeei? ia oeae /an ??aaiue S Ig A caeeoaany iecueeei, caoa
niinoa??aaeanue ii?iae?caoe?y aeoeaiino? e?cioeeio. Iieacieee
oai?ethi?ianoeaioe?? ? IAeA i?ney ?ieoaaoe?? ia?aaeuoaaee iieacieee
eiio?ieueii? a?oie, a aeoeai?noue eaoaeace aoea iecueeith.

Ii?iae?caoe?? ae an?o eaai?aoi?ieo iieaciee?a, ye? aea/aeenue, aaeaeiny
aeinyaoe eeoa i?ney i?ny/iiai eo?no iaaeeeaiaioiciiai e?eoaaiiy.

I?e o?aaeeoe?eiiio e?eoaaii? aaeaiioeaaiiie ia /an ee?i?/iiai iaeoaeaiiy
a e?ia? iaei i?noea iacia/ia iie?auaiiy ee?oeiii? oa aoii?aeueii? eaiie
?ioi?oaoo ca ?aooiie i?aeaeuaiiy caaaeueii? e?eueeino?
O-e?ioioeeo?a, O-oaeia??a oa Ig G. E?euee?noue O-noi?ani??a caeeoeeanue
a??ia?aeii aenieith. Iieacieee oai?ethi?ianoeaioe?? oa OAE-?aaaoth/eo
i?iaeoeo?a ciaoiaeeeenue ia aenieiio ??ai?, aioeieneaeaioiee iioaioe?ae
i?aai?cio caeeoaany iecueeei. Ai?iiiaeueiee noaoon i?aeoe/ii ia
a?ae??ciyany a?ae ae?oae eiio?ieueii? a?oie.

A ?ioia?e ??aeei? i?ine?aeeiaoaaeanue oaiaeaioe?y aei i?aeaeuaiiy ??aiy
S Ig A ? aaeoa?eoeeaeii? aeoeaiino? e?cioeeio oa iie?auaiiy i?ioean?a
IIE. Iaeiae e?ioeaaee ??aaiue IAeA caeeoaany aenieei, a eiai i?e??no a
1,3 ?ace ia?aaeuoaaa iieaciee caei?iaeo ae?oae. Iacia/ii c?inoaa
aioeieneaeaioiee iioaioe?ae.

Aeei?enoaiiy cai?iiiiiaaiiai iaie e?eoaaeueiiai eiiieaeno aeicaieeei
aeinyaoe ia 6-7 aeiao ii?iae?caoe?? ianiaoeeo?/ieo oaeoi??a caoenoo,
noaa?e?coaaoe ieenethaaeueiee iaoaaie?ci ? ??ai? ai?iii?a.

O?aaeeoe?eia e?eoaaiiy aino?iai iaeiioiaaiiiai inoaii??e?oo o?ea
ieaeiuei? uaeaie iaoiiaeei iacia/ia iie?auaiiy aei 6-7 aeiae iieaciee?a
?ioi?oaoo a e?ia?. Ia 12-13 aeiao caaaeueia e?euee?noue O-e?ioioeeo?a,
O-oaeia??a ? O-noi?ani??a ii?iae?coaaeanue, i?ioa a??ia?aeii c??n
a?aenioie A-e?ioioeeo?a ? ciaioeeanue e?euee?noue I-ee?oei, a ??ai?
Ig M oa G caeeoeeenue iecueeeie. Inoaoi/ia ii?iae?caoe?y an?o iieaciee?a
i?ine?aeeiaoaaeanue eeoa i?e ianoaaeaii? /a?ac i?nyoeue, e??i ??aiy Ig
G, yeee oae ? caeeoeany iecueeei.

??aaiue S Ig A ? aaeoa?eoeeaeia aeoeai?noue e?cioeeio ia 6-7 ? 12-13
aeiae niinoa?aaeaiiy aoee iecueeeie, a ?o a?aeiinia ii?iae?caoe?y
niinoa??aaeanue /a?ac i?nyoeue i?ney iia?aoeaiiai ao?o/aiiy.

Ca 6-7 ae?a e?eoaaiiy a?aeaoeanue iacia/ia iiceoeaia aeeiai?ea ?
a?io?i?/ieo iieaciee?a a e?ia?, yea i?inoaaeoaaeanue aei ia??iaeo
ee?i?/iiai iaeoaeaiiy. Iaeiae ??aaiue OAE-?aaaoth/eo i?iaeoeo?a
caeeoeany aenieei iaa?oue /a?ac i?nyoeue i?ney iia?aoeaiiai ao?o/aiiy.

A ?ioia?e ??aeei? niinoa??aaeinue a?eueo iia?eueia cieaeaiiy aeoeaiino?
i?ioean?a A?I oa i?aeaeuaiiy oaeoi??a AIC, aea ?o na?aaeiueinoaoenoe/i?
aaee/eie a??ia?aeii ??cieeeny a?ae eiio?ieueieo, iaa?oue ia 12-13 aeiao.
Ia aeeaey/enue ia a?aenooi?noue ee?i?/ieo i?iya?a ia?aianaiiai
caiaeaiiy e?noee ieaeiuei? uaeaie, i?e ianoaaeaii? /a?ac i?nyoeue, ??ai?
OAE-?aaaoth/eo i?iaeoeo?a ia?aaeuoaaee, a aeoeai?noue NIAe ? eaoaeace
aoee ieae/eie ca iieacieee eiio?ieueii? a?oie ae?oae.

Aeeiai?/ia aeine?aeaeaiiy ??ai?a ai?iii?a aeicaieeei anoaiiaeoe, ui ia
ia??iae ee?i?/iiai iaeoaeaiiy a?aeaoaaeanue ii?iae?caoe?y nae?aoe?? OOA
? ?inoe?io. ??aaiue O3 iacia/ii c?inoaa, a ei?oecieo cieaeaany. Iiaia
a?aeiiaeaiiy ??aiy O3 iaei i?noea eeoa /a?ac 2 oeaei? i?ney aeienee ?c
noaoe?iia?o, /iai ia iiaeia neacaoe i?i ei?oecie, iieaciee yeiai
caeeoaany aeaui i?aeaeuaiei.

I?e eiiieaeniiio e?eoaaii? inoaii??e?oo aaea ia 6-7 aeiao caaaeueia
e?euee?noue O-e?ioioeeo?a, O-oaeia??a oa ??aaiue Ig A a?aeiia?aeaee
iieacieeai o caei?iaeo ae?oae. Aei 12-13 aeiae a?aeaoaaeanue
ii?iae?caoe?y ?ioeo neeaaeiaeo /anoei ?ioi?oaoo, e??i Ig G,
noaa?e?caoe?y yeiai anoaiiaeaia eeoa /a?ac i?nyoeue a?ae iiiaioo
aini?oae?caoe??.

Ee?i?/iee ia?aa?a caoai?thaaiiy noi?iaiaeaeoaaany a?aeiiniith
ii?iae?caoe??th ??aiy S Ig A oa aaeoa?eoeeaeii? aeoeaiino? e?cioeeio a
?ioia?e ??aeei? aaea ia 12-13 aeiao ? iaeaea aaniethoiith /a?ac i?nyoeue
i?ney iia?aoeaiiai ao?o/aiiy.

A e?ia? i?ine?aeeiaoaaeinue a?eueo oaeaeea noaiiaeaiiy iieaciee?a
ieenethaaeueiiai iaoaaie?cio, i?ae i?e o?aaeeoe?eiiio e?eoaaii?, ? i?e
ianoaaeaii? oai?eo ia /an ee?i?/iiai iaeoaeaiiy caeeoeeenue
i?aeaeuaieie eeoa iieaciee na?oeinoie ? ??aaiue IAeA i?ney
?ieoaaoe??. A?aeiiaeaiiy ?o aaee/ei ie niinoa??aaee /a?ac 2 oeaei? ii
aeienoe? ?c noaoe?iia?o.

A ?ioia?e ??aeei? a?aeaoaaeinue iinooiiaa aeeiai?/ia cieaeaiiy ai?noo
i?iaeoeo?a IIE oa i?aeaeuaiiy oaeoi??a AIC aei 12-13 aeiae, a
ii?iae?caoe?y ?o na?aaeiueinoaoenoe/ieo aaee/ei aeyaeaia /a?ac i?nyoeue
i?ney iia?aoeaiiai ao?o/aiiy.

Ia 6-7 aeiao a?aeaoaaeanue noaa?e?caoe?y ??ai?a OOA, ?inoe?io, a ia
12-13 – O3 oa ei?oecieo.

Ii caaa?oaii? o?aaeeoe?eiiai e?eoaaiiy caaino?aiiy OII a e?ia? ae?oae
niinoa??aaeinue iacia/ia i?aeaeuaiiy e?eueeino? O-oaeia??a ? ??aiy Ig G
oa cieaeaiiy O-noi?ani??a, iaeiae ?o na?aaeiueinoaoenoe/i? cia/aiiy
caeeoeeeny a??ia?aeii a?aei?iieie a?ae iieaciee?a eiio?ieueii? a?oie
ae?oae. Caa??aaany i?aeaeuaiei iieaciee NAA, ??aaiue IAeA i?ney
?ieoaaoe??. Aeoeai?noue eaoaeace iacia/ii c?inoaea. ??ai? OOA ? O3
cieaeoaaeenue.

A ?ioia?e ??aeei? c??n ??aaiue S Ig A, aaeoa?eoeeaeia aeoeai?noue
e?cioeeio aoea iecueea, na?oeinoia i?aeaeuaia, a?aenioie i?e?inoo IAeA
caeeoeany ia iiia?aaeiueiio ??ai?, a aeoeai?noue eaoaeace o?ioe
i?aeaeueeanue.

A ia?ioeaeiiio nae?ao? ??aaiue S Ig A ? aeoeai?noue e?cioeeio
caeeoeeenue a??ia?aeii iecueeeie (10,351,34 ? 172,0714,83 a?aeiia?aeii).
A?aei?/aii oaeiae iacia/ia cieaeaiiy aeoeaiino? i?ioean?a IIE oa
iie?auaiiy aioeieneaeaioiiai iioaioe?aeo.

Ia /an e?ea?aeaoe?? yaeu caaino?aiiy o ae?oae, ye? io?eioaaee
?ic?iaeaiee iaie e?eoaaeueiee eiiieaen, a e?ia? aecia/aeanue
ii?iae?caoe?y an?o iieaciee?a ee?oeiii? ? aoii?aeueii? eaiie ?ioi?oaoo,
e??i ??aiy Ig G. Noaa?e?coaaeenue i?ioeane IIE, AIC oa ??ai? ai?iii?a.

A ?ioia?e ??aeei? niinoa??aaeinue cia/ia i?aeaeuaiiy ??aiy S Ig A ?
aaeoa?eoeeaeii? aeoeaiino? e?cioeeio oa ii?iae?caoe?y iieaciee?a
ieenethaaeueiiai iaoaaie?cio.

A nae?ao? i?eaooieo caeic ??aaiue S Ig A ? aeoeai?noue e?cioeeio
iaaeeaeaeenue aei ??ai?a caei?iaeo ae?oae (13,891,20 ? 201,4815,41
a?aeiia?aeii). Ia aeeaey/enue ia i?aeaeuaiiy na?oeinoie ? IAeA i?ney
?ieoaaoe??, aeoeai?noue NIAe ? eaoaeace aeinyaaee iieaciee?a caei?iaeo
ae?oae.

Aiae?c ?acoeueoao?a i?ioe?aoeeaeeaiiai e?eoaaiiy a a?oiao ii??aiyiiy
aeicaieea anoaiiaeoe, ui o oai?eo, ye? io?eioaaee cai?iiiiiaaiee
eiiieaen, ca a?eueo ei?ioeee i?ii?aeie /ano iie?auoaaeenue ee?oeiiee
neeaae ia?ioeaeiiai nae?aoo, eiai ?aieia?/i? aeanoeaino? oa
ooieoe?iiaeueiee noai i?eaooieo caeic.

?acoeueoaoe ?ioiieia?/ieo ? a?io?i?/ieo aeine?aeaeaiue e?ia?,
io?eiai? i?ney caaa?oaiiy o?aaeeoe?eiiai i?ioe?aoeeaeeaiiai e?eoaaiiy
OII, aeyaeee a?aeiiaeaiiy e?eueeino? O-oaeia??a. ??aaiue Ig G aoa
iecueeei. A?aeaoaaeanue oaeiae ii?iae?caoe?y iieacieea na?oeinoie,
OAE-?aaaoth/eo i?iaeoeo?a oa aeoeaiino? eaoaeace.

A ?ioia?e ??aeei? ??aaiue S Ig A oa aeoeai?noue e?cioeeio i?aeoe/ii ia
ci?ithaaeenue. Caeeoeeanue a??ia?aeii aenieith na?oeinoia ? cieaeaiith
aeoeai?noue eaoaeace.

Ia oeae /an a ia?ioeaeiiio nae?ao? ??aaiue S Ig A oa aaeoa?eoeeaeia
aeoeai?noue e?cioeeio caa?aaeeny ia iiia?aaeiueiio ??ai? (12,861,29 ?
170,6615,68 a?aeiia?aeii). Iie?iooaaany i?ioean A?I, iaeiae iieaciee
na?oeinoie, IAeA i?ney ?ieoaaoe?? ? eiai i?e??no caeeoeeeny a??ia?aeii
a?aei?iieie a?ae eiio?ieueieo aaee/ei, ye ? aeoeai?noue eaoaeace.

I?ney i?iaaaeaiiy cai?iiiiiaaiiai iaie i?ioe?aoeeaeeaiiai e?eoaaiiy OII
aaeaeiny ii?iae?coaaoe e?euee?noue oee?eoethth/eo a e?ia? O-oaeia??a,
??aaiue Ig G oa ieenethaaeueiee iaoaaie?ci.

A ?ioia?e ??aeei? ? ia?ioeaeiiio nae?ao? ??aaiue S Ig A oa aeoeai?noue
e?cioeeio aoee aeecueeeie aei ii?ie (aeey ia?ioeaeiiai nae?aoo 14,881,22
? 218,6918,16 a?aeiia?aeii), noaa?e?coaaeenue i?ioeane IIE oa
aioeieneaeaioiee iioaioe?ae a oeeo a?ieia?/ieo noano?aoao.

I?e aea/aii? ee?i?/ii? aoaeoeaiino? a?ae canoinoaaiiy o?aaeeoe?eieo
i?ioe?aoeeaeeaieo caoiae?a anoaiiaeaii, ui e?euee?noue caaino?aiue i?ney
ia?oiai ?ieo e?eoaaiiy nei?ioeeinue a 1,6 ?ac?a, a ca 10 ?ie?a a 3,8. A
oie /an, eiee i?e canoinoaaii? cai?iiiiiaaiiai eiiieaeno ?o
e?euee?noue i?ioyaii ?ieo ciaioeeanue a 2,1 ?ac?a, ca 10 — a 8,5.

Ocaaaeueithth/e ?acoeueoaoe aeine?aeaeaiue ie ae?eoee aeniiaeo, ui
aeeoa?aioe?eiaaia canoinoaaiiy a eiiieaeniiio e?eoaaii? ae?oae c
aino?eie caiaeueieie i?ioeanaie uaeaiii-eeoeaai? ae?eyiee oa o?ii?/iei
ia?aio?iaoiciei ia?ioeoii oeiae?io, a?iaioeieneaeaio?a i?yii? ae?? ?
aaeaioiaaio aeicaiey? iie?ioeoe ?o ia?aa?a ca ?aooiie ae?aaeaiiai
?ioiiei?aaoth/iai, iaia?aiinoaa?e?coth/iai oa aaeaioaoe?eiiai aoaeo?a.

Ee?i?/ia niinoa?aaeaiiy aeicaieeei anoaiiaeoe, ui o oai?eo, ye?
io?eioaaee iaoiaaiaoe/ia e?eoaaiiy a a?eueo ei?ioe? no?iee
a?aeaoaaeanue ii?iae?caoe?y caaaeueiiai noaio, e?ea?aeaoe?y aino?eo
yaeu caiaeaiiy, iie?auaiiy i?e?ia?ieia?/ii? ? oeeoieia?/ii? ea?oei
?aiiaiai aenoaeaoo, ia?ioeaeiiai nae?aoo oa E??, ui aeicaieeei ciaioeoe
o?eaae?noue ia?aaoaaiiy oai?eo ia e?ea?iyiiio e?aeeo: i?e aino?iio
ai?eiiio e?ioaaeai?o? ia 1,1, aino?iio ai?eiiio e?ioaaeai?o? o ae?oae,
ye? i?aeeyaee ae?? ?ii?coth/iai aei?ii?ithaaiiy ia 1,3, aaeaiioeaaiii?
ia 1,4, inoaii??e?o? ia 3,2, caaino?aii? OII ia 1,6 e?aeei-aei?a.

Caaaeueiee aeiiii?/iee aoaeo a?ae aeei?enoaiiy cai?iiiiiaaieo iaie
iaoiaaiaoe/ieo e?eoaaeueieo eiiieaen?a neeaa 370,13 a?eaaiue ca aeiao.

AENIIAEE

1. Ii?ooaiiy ?icaeoeo aeeoeie a aioa- ? iinoiaoaeueiiio ia??iaeao a
cia/i?e i??? a?aeia?aaea?oueny ia iioiaaiac? ? i?ecaiaeeoue aei
cieaeaiiy caoenii-aaeaioaoe?eieo iiaeeeainoae i?aai?cio, ni?ey?
oi?ioaaiith a iueiio iaoieia?/iiai neiioiiieiiieaeno (aoi?eiiee
?ioiiaeao?oeeo, aeoea?caoe?y a?eueii?aaeeeaeueiiai ieeneaiiy, cieaeaiiy
aioeieneaeaioiiai iioaioe?aeo, no?ani?iee aieea), yeee ?aae?co?oueny a
oeaieiao uaeaiii-eeoeaai? ae?eyiee a 11% aeiaaee?a a?ae caaaeueii?
e?eueeino? ae?oae c ai?eiith o??o?a?/iith iaoieia??th.

2. I?ia?aeieie i?e?ii?aai?ciaie a ao?ieia?? e?ioaaeai?oo,
aaeaiioeaaiiie, inoaii??e?oo oa caaino?aii? o?ii?/iiai ia?aio?iaoiciiai
ia?ioeoo o ae?oae ? cieioenoee ? ai?aea?iaeueiee noao?eieiee (Staph.
aureus, epidermidis), aaiie?oe/iee no?aioieie (Str. haemoliticus) a
iiiieoeueoo??, ye? aieiae?thoue ae?aaeaieie iaoiaaiieie aeanoeainoyie
oa aioea?ioeei?acenoaioi?noth. O ae?oae, ye? i?aeiaee aieeao
?ii?coth/iai aei?ii?ithaaiiy, niinoa??aaeinue i?aaaethaaiiy
oiiaii-iaoiaaiieo eieiaeo eoeueoo? oa ?o anioe?aoe?e.

3. Aino?? caiaeuei? caoai?thaaiiy uaeaiii-eeoeaai? ae?eyiee, o?ii?/iee
ia?aio?iaoiciee ia?ioeo a oac? caaino?aiiy noi?iaiaeaeothoueny
noi?an??th ee?oeiii? oa aoii?aeueii? eaiie ?ioi?oaoo e?ia?, ?ioiai?
??aeeie, ia?ioeaeiiai nae?aoo. Iaea?eueo ?ioi?iaoeaieie iieacieeaie ?
O-e?ioioeeoe (A-?OE), ?ioiiaeiaoe?i G ne?iaaoee e?ia?, S Ig A oa
aaeoa?eoeeaeia aeoeai?noue e?cioeeio ?ioiai? ??aeeie ? ia?ioeaeiiai
nae?aoo. ??ciiiai?aaeai?noue ci?i eiioeaio?aoe?? S Ig A a ?ioia?e
??aeei? ? ia?ioeaeiiio nae?ao? oa ?ioiiaeiaoe?io A ne?iaaoee e?ia?
aecia/a?oueny ??aiai ei?oecieo.

4. Aino?? caiaeuei? i?ioeane uaeaiii-eeoeaai? ae?eyiee o ae?oae ?
o?ii?/iee ia?aio?iaoiciee ia?ioeo oa?aeoa?ecothoueny aeoea?caoe??th
a?eueii?aaeeeaeueiiai ieeneaiiy oa ?ia?aoaaiiyi aeoeaiino?
aioeieenethaaeueieo oa?iaio?a e?ia?, ?ioiai? ??aeeie oa ia?ioeaeiiai
nae?aoo. I?e o?ii?/iiio ia?ioeo? aeai? ii?ooaiiy caa??aathoueny iaa?oue
a ia??iae ?ai?n??. O ae?oae c e?ioaaeai?oii, ye? i?aeiaee ae??
?ii?coth/iai aei?ii?ithaaiiy, ?icaeaa?oueny “neiae?ii ia?ieneaeaoe??”.

5. ?ioaa?aoeaia ? aeeoa?aioe?eiaaia ?aaoeyoe?y ia?aa?ao aino?iai
caiaeaiiy e?ioaoe/ieo aoce?a, ieaeiuei? uaeaie oa caaino?aiiy
o?ii?/iiai ia?ioeoo iaoiiaeth?oueny ??aiai OOA, O3, ei?oecieo, ae?y
yeeo iai?aaeaia ia ?aae?caoe?th aaeaioaoe?eii-eiiiainaoi?ieo ?aaeoe?e
i?aai?cio. O ae?oae, ye? iaee iaoyaeeeaee ?aae?aoe?eiee aiaiiac,
niinoa??aa?oueny aeoeaia ?aaeoe?y a?iio?ca?ii-iaaeie?eiai? nenoaie oa
cieaeaiiy ooieoe?iiaeueii? aeoeaiino? ueoiaeaeii? ? i?aeoeoieiai?
caeic. I?e caaino?aii? o?ii?/iiai ia?ioeoo ii?ooo?oueny i?eioeei
iaaaoeaiiai cai?ioiueiai ca’yceo i?ae a?iio?cii ? ueoiaeaeiith caeicith.

6. A eiiieaen? iaoiaaiaoe/iiai aieeao ia ia?aa?a aino?eo caiaeueieo
caoai?thaaiue oa o?ii?/iiai ia?ioeoo o ae?oae aaaeeeaa i?noea caeia?
canoinoaaiiy i?aia?aoo iie?iaioeaeii? i?e?iaee oeiae?io ? e?cioeeio, ui
ni?ey? ii?aeiaiith aoaeo?a ?ioiiei?aeoe?? ? noaa?e?caoe?? ee?oeiieo oa
aoii?aeueieo oaeoi??a caoenoo ia ??ai? oe?e?niiai i?aai?cio ? ii?iaeieie
?ioa, cie?aia.

7. I?aeaeuaiiy i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a, cieaeaiiy
aeoeaiino? oa?iaioaoeaii? aioeieneaeaioii? nenoaie oa aaeaioaoe?eieo
iiaeeeainoae i?aai?cio aeeoeie a ia??iae ii/aoeiaeo ee?i?/ieo i?iya?a
aino?eo caiaeueieo i?ioean?a uaeaiii-eeoeaai? ae?eyiee ? i?e
o?ii?/iiio ia?ioeo?, caeaaei?noue ?o ci?i a?ae iicieia?/ii? oi?ie
caoai?thaaiiy, neoaeaoue iieacaiiyi aei naeaeoeaiiai aeei?enoaiiy a
caaaeueiiio ? i?noeaaiio e?eoaaii? aioeieneae?a oa aaeaioiaai?a.

8. Eiia?iiaaia canoinoaaiiy e?ea?nueeeo cania?a aeey aeeoa?aioe?eiaaiiai
e?eoaaiiy c aeei?enoaiiyi ?ioiiei?aeoi??a (oeiae?i, e?cioeei),
aioeieneaeaio?a (oieioa?ie-aoeaoao, anei?ooei, anei?a?iiaa eeneioa,
oi?o?ie, ie?y iae?ieoe), aaeaioiaaio ae?aacieo, oeaieiiiai aoaeaoeaaiai
ni?aaioo AOO-I, i?oaoeeaeo, eaca?iiai aei?ii?ithaaiiy oa e?eoaaeueii?
o?ceoeueoo?e caaacia/eei iie?ioaiiy ia?aa?ao caiaeueieo caoai?thaaiue ?
i?enei?aiiy ii?iae?caoe?? ee?i?ei-eaai?aoi?ieo iieaciee?a. I?io?eaeoe/i?
caoiaee i?e o?ii?/iiio ia?ioeo? aeicaieeee cia/ii ciaioeoe e?euee?noue
?aoeeaeea?a, ?o o?eaae?noue, iie?aueee ooieoe?iiaeueio aeoeai?noue
i?eaooieo caeic oa ?aieia?/i? aeanoeaino? nae?aoo (Iaoaio Oe?a?ie ?
24547 A).

I?AEOE*I? ?AEIIAIAeAOe??

1. Aeey ia’?eoeaii? ioe?iee ia?aa?ao aino?eo caiaeueieo i?ioean?a
uaeaiii-eeoeaai? ae?eyiee ? o?ii?/iiai ia?ioeoo aeioe?eueii i?iaiaeeoe
aeeiai?/ia oeeoieia?/ia oa i?e?ia?ieia?/ia aeine?aeaeaiiy ?aiaaiai
aenoaeaoo ? ia?ioeaeiiai nae?aoo, aecia/aiiy ??aiy S Ig A,
aaeoa?eoeeaeii? aeoeaiino? e?cioeeio, iieaciee?a oai?ethi?ianoeaioe?? a
?ioia?e ??aeei? oa ia?ioeaeiiio nae?ao?.

2. A ee?i?/i?e i?aeoeoe? aeeoy/i? uaeaiii-eeoeaai? o??o?a??
i?iiiio?oueny canoiniaoaaoe ne?aeoth/? aeeoa?aioe?eiaai? e?eoaaeuei?
eiiieaene:

· aino?ee ai?eiee e?ioaaeai?o: oeiae?i N5, oieioa?ie-aoeaoao,
anei?ooei, ae?acie?i i?ioyaii /ano ia?aaoaaiiy a noaoe?iia??;

· aino?ee ai?eiee e?ioaaeai?o o ae?oae, ye? i?aeiaee ae?? ?ii?coth/iai
aei?ii?ithaaiiy: oeiae?i N7, ia?ae?ioaoe/ia aaaaeaiiy aaioai?oeeio aai
e?ieii?oeeio, oieioa?ie-aoeaoao, anei?ooei, ae?aacie i?ioyaii ia??iaeo
noaoe?iia?iiai e?eoaaiiy ? aeiaeaoeiai i?ioyaii 21 aeiae i?ney aeienee,
ae?acie?i i?ioyaii 7 ae?a;

· aaeaiioeaaiiia: oeiae?i N7, ia?ae?ioaoe/ia aaaaeaiiy aaioai?oeeio aai
e?ieii?oeeio, oieioa?ie-aoeaoao, anei?ooei (iiaeai?ia aeica), ae?acie?i
i?ioyaii ia??iaeo noaoe?iia?iiai e?eoaaiiy.

On?i oai?ei oeeo a?oi i?iaiaeeoueny iine?aeiaia naiaoe?y ?aiaaiai oiaeo
? ii?iaeieie ai?eieea ?ic/eiaie 1% e?cioeeio oa 5% oi?o?ieo, iaeeaaeaiiy
ia ?aiaao iiaa?oith oeaieiiiai aoaeaoeaaiai ni?aaioo (AOO-I),
eaca?ioa?ai?y ii aeoioieoo?i?e iaoiaeeoe? a ?aaeei? 5-25 iAo/ni2 c
aeniiceoe??th 1-2 oaeeeie i?ioyaii 6-7 ae?a, ianaae eii??oeaai? ciie
N7-9 oa e?eoaaeueia a?iianoeea.

· aino?ee iaeiioiaaiiee inoaii??e?o o?ea ieaeiuei? uaeaie: ?iooc?eia
oa?ai?y i?ioyaii o?ueio ae?a (10% ?ic/ei aetheice, ?ic/ei ??iaa?a,
?inoe?i 1 IAe ia 4 a?aie aetheice, ?ic/ei anei?a?iiai? eeneioe, 7,5%
oei?enoee eae?e), ia’?i yei? aecia/a?oueny a?eii oa aaaith aeeoeie.
Aioo??oiueii’yciai oeaoaeinii?eie ia?oi? aaia?aoe?? oa oeiae?i N7-10,
oieioa?ie-aoeaoao, i?eia?o, ae?acie?i, ae?aacie i?ioyaii /ano
ia?aaoaaiiy a noaoe?iia??.

Ne?ae i?iaiaeeoe aeoeaia aaaaeaiiy a ?aiaaee o?ae ?ic/ei?a e?ieii?oeeio
? oi?o?ieo i?ioyaii 5 ae?a, o?e ?ace ia aeiao, eaca?ioa?ai?y ii
neaioth/?e iaoiaeeoe? a ?aaeei? 25 iAo/ni2, aeniiceoe?y 5-10 oaeeei
i?ioyaii 12 ae?a, iaeaaeaiiy i?ioyaii 5 ae?a iia’ycee c i?oaoeeaeii, a
iio?i c a?iicieai AI. I?ioaiiy ii?iaeieie ?ioa ?ic/eiaie 1% e?cioeeio ?
5% oi?o?ieo, e?eoaaeueia o?ceoeueoo?a aeey aeoaaeueii? ? i?i?/ii?
ioneoeaoo?e.

· o?ii?/iee ia?aio?iaoiciee ia?ioeo a ia??iae caaino?aiiy: oeiae?i N3,
oieioa?ie-aoeaoao, anei?ooei, ae?acie?i i?ioyaii 7 ae?a, ?inoeeyoe?y a
i?ioieiao nenoaio 1% ?ic/eio e?cioeeio c iine?aeoth/ei ianoaaiiyi caeice
? aaaaeaiiyi ?ic/eio oi?o?ieo, i?ioaiiy ii?iaeieie ?ioa ?ic/eiii 1%
e?cioeeio 5 ?ac?a ia aeaiue, eaca?ioa?ai?y ii aeoioieoo?i?e iaoiaeeoe? a
?aaeei? 5-25 iAo/ni2 c aeniiceoe??th 1-2 oaeeeie N7, iia’ycee c
aeeiaeneaeii oa ?iaeiiaoaoeeiiaith iaccth, eaaeee ianaae caeice 3-4 ?ace
ia aeaiue i?ioyaii 3-5 oaeeei aei ? i?ney ?aee;

· o?ii?/iee ia?aio?iaoiciee ia?ioeo a ia??iae ?ai?n??:
oieioa?ie-aoeaoao, anei?ooei, ae?aacie i?ioyaii 21 aeiae. ?inoeeyoe?y
e?ea?nueeeo i?aia?ao?a a i?ioieiao nenoaio i?iaiaeeoueny a oae?e
iine?aeiaiino?: i?ney ianoaaiiy caeice ? /anoeiaiai a?aeoiaeaeaiiy c ia?
ca’yceiaiai nae?aoo aaiaeeoueny 0,3-0,5 ie 1% ?ic/eio e?cioeeio, /a?ac
10-15 oaeeei caeico iiaoi?ii ianothoue ? i?ney aaaeoaoe?? ai?noo
aeiaeaoeiai aaiaeyoue 5% ?ic/ei oi?o?ieo. I?ioeaaeo?a cae?enith?oueny
uiaeaiii i?ioyaii 3 aei?a. Ia 4 aeaiue aaiaeeoueny ie?y iae?ieoe 0,4-0,7
ie. Iiaoi?i? aaaaeaiiy ?? cae?eniththoue ua o?e/? c ?ioa?aaeii a i’youe
ae?a, i?iaiaeeoueny i?ioaiiy ii?iaeieie ?ioa (aei ? i?ney ?aee) 1%
?ic/eiii e?cioeeio. Ia ae?eyieo i?iaeoe?? caeice aae?e-iaiiiaee eaca? c
aeei?enoaiiyi ?icoieoniaaieo ianaaeie a ?aaeei? 1 iAo/ni2, o?eaae?noue
i?ioeaaeo?e 2-3 oaeeeie N10. I?ioe?aoeeaeeaia e?eoaaiiy i?iaiaeeoueny
aea?/? ia ??e (aaniith ? ainaie).

Aeicoaaiiy e?ea?nueeeo i?aia?ao?a c ?ic?aooieo ia ea/iane o?ea oa ia
aeiao:

· aioea?ioeee oeaoaeinii?eiiaiai ?yaeo ia?oi? aaia?aoe?? aeey
aioo??oiueii’yciaiai aaaaeaiiy – 50-100 ia/ea;

· aioea?ioeee aeey ia?ae?ioaoe/iiai aaaaeaiiy – ?aciaa aeica neeaaea?
1/4 aeiaiai? aeice (aeiaiaa aeica aaioai?oeeio – 3-5 ia/ea, e?ieii?oeeio
– 10-20 ia/ea);

· oeiae?i 1-5 ia ia aeiao;

· oieioa?ie-aoeaoao – 5-10 ia ia aeiao;

· anei?ooei 0,025 – 0,1 a ia aeiao;

· ae?acie?i 0,02 – 0,15 a ia aeiao;

· ae?aacie (aei 1 ?ieo – 0,001 a ia aeiao; 1-3 ?iee – 0,002 a; 4-8 ?ie?a
– 0,003 a; 9-12 ?ie?a – 0,004 a; noa?oa 12 ?ie?a – 0,005 a ia aeiao);

· i?eia?o (ae?oyi ynaeueiiai a?eo ii 2 ianoeeee ia aeiao, aeioe?eueiiai
– ii 4, oe?eueiiai – ii 7).

3. C iaoith caiia?aaiiy oa nai?/anii? ei?aeoe?? iiaeeeaeo oneeaaeiaiue
? ii?ooaiue a caaaeueiiio ? i?noeaaiio noaoon? o ae?oae, ye? ia?aianee
aino?? ai?ei? caoai?thaaiiy uaeaiii-eeoeaai? ae?eyiee oa oai??th/eo ia
o?ii?/iee ia?aio?iaoiciee ia?ioeo, iaiao?aeiee iaaeyae ia o?eueee
e?ea?y-noiiaoieiaa, a e niaoe?ae?no?a ?ioeo i?io?e?a. Iioeiaeueiith
oi?iith ?o icaei?iaeaiiy ? aeeniaina?ia caaacia/aiiy, a o?eaae?noue
?aaa?e?oaoe?eiiai ia??iaeo ? ianya e?eoaaeueieo caoiae?a iiaeii?
ae??ooaaoenue ?iaeea?aeoaeueii a caeaaeiino? a?ae iicieia?/ii? oi?ie
caoai?thaaiiy ? iayaiino? noiooiuei? iaoieia??.

nienie iaoeiaeo i?aoeue, iioae?eiaaieo ca oaiith

aeena?oaoe??

noaoo? o oeaio?aeueieo iaoeiaeo aeaeaiiyo

1. Canoinoaaiiy aioeieneaeaio?a o eiiieaeniiio e?eoaaii? ae?oae c
aino?ei ai?eiei e?ioaaeai?oii, ye? i?aeaeaaaeenue aieeao ?ii?coth/iai
ii?ii?iaiiy //Iiaeie noiiaoieia??.– 1997.– ? 4.– N. 95-97.

2. ?aioaaiieia?/ia oa?aeoa?enoeea o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo
o ae?oae //Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.– 1997.– ? 21.– N.
83-89.

3. Ioe?iea aoaeoeaiino? e?eoaaeueieo caoiae?a i?e caaino?aii?
o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o ae?oae ii iieacieeao oeeoia?ai
ia?ioeaeiiai nae?aoo // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.– 1997.– ?
24.– N. 36-43.

4. Oeyoe ei?aeoe?? ai?iiiaeueieo ii?ooaiue o ae?oae c aino?ei ai?eiei
e?ioaaeai?oii, ye? i?aeeyaee ae?? ?ii?coth/iai aei?ii?ithaaiy //I?iaeaie
aeieia?? oa iaaeeoeeie.– 1997.– ? 1-2.– N.47-49 (ni?aaao.
I.N.Ne?eii?eia).

5. Ci?ie ye?nieo ? e?euee?nieo oa?aeoa?enoee i?e?iaii? oei?e
ia?ioeaeiiai nae?aoo a aeeiai?oe? e?eoaaiiy caaino?aiiy o?ii?/iiai
ia?aio?iaoiciiai ia?ioeoo o ae?oae, aeoeaiee ia?aa?a // Aanoiee i?iaeai
aeieiaee e iaaeeoeeiu.– 1997.– ? 25.– N. 134-139.

6. Aeeiaieea eciaiaiee eiioiieiae/aneeo iieacaoaeae o aeaoae i?e ino?ii
aiieiii iaeiioiaaiiii inoaiieaeeoa ieaeiae /aethnoe //Aanoiee
noiiaoieiaee.– 1998.– ? 1.– N. 53-56.

7. Ae?aaiinoe/ia ?ioi?iaoeai?noue oeueo?acaoeiaiai aeine?aeaeaiiy i?e
iaoieia?? i?eaooieo caeic o ae?oae // Aanoiee i?iaeai aeieiaee e
iaaeeoeeiu.– 1997.– ? 27.– N. 79-84.

8. I?e?ia?ieia?/ia oa?aeoa?enoeea aino?iai ai?eiiai e?ioaaeai?oa o
ae?oae, ye? i?aeeyaee ae?? ?ii?coth/iai aei?ii?ithaaiiy //I?iaeaie
aeieia?? oa iaaeeoeeie.– 1997.– ? 1-2.– N. 49-51.

9. I?ioe?aoeeaeeai? caoiaee o ae?oae, oai?eo ia o?ii?/iee
ia?aio?iaoiciee ia?ioeo // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.–
1997.– ? 30.– N. 41-47.

10. Ai?iiiaeueiue noaoon o aeaoae i?e ino?ii aiieiii iaeiioiaaiiii
inoaiieaeeoa ieaeiae /aethnoe //Aanoiee noiiaoieiaee.– 1998.– ? 2.– N.
63-65.

11. ?acoeueoaoeai?noue aeeniaina?iiai caaacia/aiiy ae?oae c o?ii?/iei
ia?aio?iaoiciei ia?ioeoii // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.–
1997.– ? 31.– N. 118-123.

12. Ei??aeoeey i?ioeannia ia?aeeniiai ieeneaiey eeieaeia o aeaoae i?e
ino?ii aiieiii iaeiioiaaiiii inoaiieaeeoa ieaeiae /aethnoe //Aanoiee
noiiaoieiaee.– 1998.– ? 2.– N. 66-69.

13. Aioeieneaeaioia nenoaia ? ia?aeenia ieeneaiiy e?i?ae?a a ?ioia?e
??aeei? i?e aino?iio ai?eiiio e?ioaaeai?o? o ae?oae, ye? i?aeaeaaaeenue
aeiaaio?eaae?e ae?? iaeeo aeic ?ii?coth/iai aei?ii?ithaaiiy // Aanoiee
i?iaeai aeieiaee e iaaeeoeeiu.– 1998.– ? 9.– N. 94-101 (ni?aaao.
I.A.?eaaeia).

14. Ninoiyiea ooieoeee nenoaiu aeiioec – ueoiaeaeiay aeaeaca i?e
ia?ioeoa o aeaoae //Noiiaoieiaey.– 1988.– ? 3.– N. 65-67 (niaao.
A.Ae.Neaei?a, I.A.?uaaeia, AE.Oeyooa).

15. Iiuo aeeniaina?ecaoeee o aeaoae n ainiaeeoaeueiuie caaieaaaieyie
nethiiuo aeaeac //Niaa?oainoa. i?aai. oi?i noiiao. iiiiue ianaeaieth:
O?oaeu OeIEEN.– I.: 1986.– O. 17.– N. 129-131 (niaao. I.A.?uaaeia).

iaoaio

16. Can?a i?io?eaeoeee caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo
o ae?oae. Iaoaio Oe?a?ie ? 24547 A a?ae 21.07.98 ?.

noaoo? o ca??ieeao iaoeiaeo i?aoeue

17. Aaeoa?eoeeaeia aeoeai?noue e?cioeeio ?ioiai? ??aeeie o ae?oae,
i?iiia?iaaieo c aino?eie oi?iaie aiaiaeeoeeoo //Aeooaeuei? ieoaiiy
noiiaoieia?? oa caaaeueii? iaaeeoeeie: Iaoe. eiio. aei 30-??//y noiiao.
o-oo oa 70-??//y i?io. A.?.Ne?ioe.– Aei?i?iiao?ianuee, 1993.– N. 187-189
(ni?aaao. I.A.Ao?ae?e, E.?.Ai?uiaa, A.I.Eueaiae/).

18. Ai?iiiaeueiee niaeo? ieacie e?ia? ae?oae c aino?ei ai?eiei
e?ioaaeai?oii uaeaiii-eeoeaai? ae?eyiee, ye? i?aeeyaee ae?? iaeeo aeic
?ii?coth/iai aei?ii?iaiiy //Aeooaeuei? ieoaiiy i?oiiaaee/ii?
noiiaoieia??: Ca. iaoe. i?aoeue iaoe.-i?aeo. eiio.– Iieoaaa, 1996.– N.
121-123.

19. Oeeoieia?/ia ea?oeia ia?ioeaeiiai nae?aoo a aeeiai?oe? e?eoaaiiy
caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o ae?oae //Aeooaeuei?
ieoaiiy i?oiiaaee/ii? noiiaoieia??: Ca. iaoe. i?aoeue iaoe.-i?aeo.
eiio.– Iieoaaa, 1996.– N. 123-124.

20. Nenoaia ?aaaeeeoaoeee e aeeniaina?iia iaania/aiea aeaoae, aieueiuo
o?iie/aneei ia?aioeiaoiciui ia?ioeoii //Eiiieaeniia ea/aiea e
i?ioeeaeoeea noiiao. caaieaaaiee: Iaoa?. VII nuacaea noiiaoieiaia ONN?.–
Eeaa, 1989.– N. 317-318 (niaao. I.A.?uaaeia, E.A.ssoeaiei).

21. Iee?iaeieiae/aneay oa?aeoa?enoeea ino?uo aiieiuo eeioaaeaieoia
/aethnoii-eeoeaaie iaeanoe o aeaoae //Ii?oiooieoeeiiaeueiua e
eeeie/aneea aniaeou i?iaeai noiiaoieiaee: Iaoa?. iao/.-i?aeo. eiio.–
Aeiiaoee, 1993.– *. 3.– N. 69.

22. I?eiaiaiea oeiaeeia a eiiieaeniii ea/aiee aeaoae n ino?uie aiieiuie
eeioaaeaieoaie /aethnoii-eeoeaaie iaeanoe //Aeooaeuei? ieoaiiy
noiiaoieia?? aeeoy/iai a?eo ? i?oiaeiio??: Iaoa?. aeii.– Iieoaaa, 1993.–
N. 78-79 (niaao. A.A.Ao?aeee, I.I.E?e/aaneay).

23. Aeeeoaeueiinoue noaoeeiia?iiai ea/aiey aeaoae n ainiaeeoaeueiuie
caaieaaaieyie /aethnoii-eeoeaaie iaeanoe ?aaeeiaeoeaii caa?yciaiiie ciiu
// Aeooaeuei? ieoaiiy noiiaoieia?? aeeoy/iai a?eo ? i?oiaeiio??: Iaoa?.
aeii.– Iieoaaa, 1993.– N. 79-80 (niaao. A.A.Ao?aeee, E.I.Ianeae,
A.I.Ianeae).

24. ?ioiieia?/iee noaoon ii?iaeieie ?ioa o ae?oae c aino?ei ai?eiei
e?ioaaeai?oii, ye? i?aeeyaee ae?? ?ii?coth/iai aei?ii?iaiiy //Iniiai?
noiiaoieia?/i? caoai?thaaiiy, ?o i?io?eaeoeea oa e?eoaaiiy: Iaoa?.
aeii.– Iieoaaa, 1996.– N. 92-93.

25. Aeei?enoaiiy oeiae?io, aioeieneaeaio?a ? aae?e-iaiiiaiai eaca?a a
eiiieaeniiio e?eoaaii? caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo
o ae?oae //Aeooaeuei? ieoaiiy oai?aoe/ii? oa ee?i?/ii? iaaeeoeeie ia
no/aniiio ??ai?: Iaoa?. aeii. iaoe. eiio.– Iieoaaa, 1996.– N. 410-411.

26. E?ioio?iiia aioeaaeoa??aeueia oa?ai?y a einieaeniiio e?eoaaii?
aino?eo ai?eieo e?ioaaeai?o?a uaeaiii-eeoeaai? ae?eyiee o ae?oae
//Aeooaeuei? ieoaiiy oai?aoe/ii? oa ee?i?/ii? iaaeeoeeie ia no/aniiio
??ai?: Iaoa?. aeii. iaoe. eiio.– Iieoaaa, 1996.– N. 412.

27. Noai i?e?ia?ioeaiico ?ioiai? ii?iaeieie oa ?aie ?
aioea?ioeei-/ooeea?noue eiai i?aaenoaaiee?a i?e aino?iio iaeiioiaaiiiio
inoaii??e?o? ieaeiuei? uaeaie o ae?oae //Aeooaeuei? ieoaiiy oai?aoe/ii?
oa ee?i?/ii? iaaeeoeeie ia no/aniiio ??ai?: Iaoa?. aeii. iaoe. eiio.–
Iieoaaa, 1996.– N. 413-414.

?ioi?iaoe?ei? eenoe

28. Aeeniaina?ecaoeey aeaoae n ainiaeeoaeueiuie caaieaaaieyie nethiiuo
aeaeac: Eioi?i. ienueii.– Eeaa, 1987.– 2 n. (niaao.: I.A.?uaaeia).

29. Iaoiae e?eoaaiiy aino?eo ai?eieo e?ioaaeai?o?a uaeaiii-eeoeaai?
ae?eyiee o ae?oae, ye? i?aeeyaee ae?? ?ii?coth/iai aei?ii?ithaaiiy:
?ioi?i. eeno.– Ee?a, 1997.– 2 n.

30. Iaoiae i?io?eaeoeee caaino?aiiy o?ii?/iiai ia?aio?iaoiciiai
ia?ioeoo o ae?oae: ?ioi?i. eeno.– Ee?a, 1997.– 2 n.

oace iaoeiaeo aeiiia?aeae

31. Ea/aiea o?iie/aneiai ia?aioeiaoiciiai ia?ioeoa o aeaoae a ia?eiae
iaino?aiey //Aeooaeueiua aii?inu noiiaoieiaee: Oac. IX ?anioae. eiio.
iieiaeuo o/aiuo.– Iieoaaa, 1988.– N. 107-108.

32. I?ioeeaeoeea iaino?aiey o?iie/aneiai ia?aioeiaoiciiai ia?ioeoa o
aeaoae //Aeooaeueiua aii?inu noiiaoieiaee: Oac. IX ?anioae. eiio.
iieiaeuo o/aiuo.– Iieoaaa, 1988.– N. 108-109.

33. Acaeiiioiioaiey iee?iaeieiae/aneiai iaecaaea n iee?iaiie oei?ie
nae?aoa ieieiooiuo aeaeac a ii?ia e i?e ia?ioeoa o aeaoae
//Iao/ii-oaoie/aneee i?ia?ann, io?aia ie?oaeathuae n?aaeu: Oac. aeiee.
iae. iao/.-i?aeo. eiio.– Iieoaaa, 1988.– N. 61-62.

34. ?aaeoeey i?aaiecia ?aaaiea, no?aaeathuaai o?iie/aneei ia?ioeoii, ia
ino?ia yeciaaiiia ia?aioeaaeaeaiea //Iao/ii-oaoie/aneee i?ia?ann, io?aia
ie?oaeathuae n?aaeu: Oac. aeiee. iae. iao/.-i?aeo. eiio.– Iieoaaa,
1988.– N. 63-63 (niaao. I.A.?uaaeia).

35. Eiioiiiiaeoee?othuaa aeeyiea iao?ey ioeeaeiaoa a eiiieaeniii
ea/aiee o?iie/aneiai ia?aioeiaoiciiai ia?ioeoa o aeaoae
//Iao/ii-oaoie/aneee i?ia?ann, caei?iauea naeueneiai ianaeaiey,
ooiaeaiaioaeueiua e i?eeeaaeiua i?iaeaiu iaaeeoeeiu e aeieiaee: Oac.
aeiee. iae. iao/.-i?aeo. eiio.– Iieoaaa, 1989.– N. 88.

36. No?oeoo?a e /anoioa ainiaeeoaeueiuo caaieaaaiee /aethnoii-eeoeaaie
iaeanoe o aeaoae //Ninoiyiea i?oiaeiioe/aneie iiiiue a NNN? e
ia?niaeoeau aa ?acaeoey: Oac. I Ananithc. eiio.– Iieoaaa, 1990.– N.
168-169 (niaao. A.A.Aaiyeei).

37. Oeeoieiae/aneay oa?aeoa?enoeea ?aiaaiai yenoaeaoa i?e ino?uo
eeioaaeaieoao o aeaoae //Aeooaeueiua aii?inu noiiaoieiaee: Oac. aeiee.
eiio., iina. 70-eaoeth ei-oa.– Iieoaaa, 1991.– N. 225-226.

38. Aeeiaieea no?oeoo?u e /anoiou ainiaeeoaeueiuo cathieaaaiee
/aethnoii-eeoeaaie iaeanoe o aeaoae //Iaoeiaa anoaoaoa tha?ey?a: Oac.
aeii. iaoe.-i?aeo. eiio., i?ena. 70-??//th i?io. I.O.Iaeneiaiea.–
Iieoaaa, 1992.– N. 179-181 (niaao. A.A.Ao?aeee, I.I.E?e/aaneay).

39. Ninoiyiea iieacaoaeae naiaiaeii?aaeeeaeueiiai ieeneaiey niaoaiiie
nethiu e ia?ioeaeiiai nae?aoa o aeaoae e eeoe iieiaeiai aic?anoa
//Iaoeiaa anoaoaoa tha?ey?a: Oac. aeii. iaoe.-i?aeo. eiio., i?ena.
70-??//th i?io. I.O.Iaeneiaiea.– Iieoaaa, 1992.– N. 181-182 (niaao.
I.A.?uaaeia, E.A.ssoeaiei, A.A.Ao?aeee, I.TH.Aiae?eyiiaa).

aiioaoe?y

Oea/aiei I.?. Iaoiaaiaoe/i? iniaeeaino? caiaeueieo i?ioean?a
uaeaiii-eeoeaai? ae?eyiee o ae?oae oa aeeoa?aioe?eiaai? i?aeoiaee aei ?o
e?eoaaiiy.– ?oeiien.

Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe ca
niaoe?aeuei?noth 14.01.22 – noiiaoieia?y.– Oe?a?inueea iaaee/ia
noiiaoieia?/ia aeaaeai?y, Iieoaaa, 1998 ??e.

Aeena?oaoe?y i?enay/aia ieoaiiyi iaoiaaiaco oa aeeoa?aioe?eiaiiio
e?eoaaiith aino?eo caiaeueieo caoai?thaaiue uaeaiii-eeoeaai? ae?eyiee oa
o?ii?/iiai ia?aio?iaoiciiai ia?ioeoo o ae?oae. A ?iaio? i?aaenoaaeaiee
iiaee iai?yiie o aea/aii? iaoai?ci?a ?icaeoeo oa e?eoaaiiy caiaeueieo
i?ioean?a uaeaiii-eeoeaai? ae?eyiee. Aecia/ai? iniaeeaino? nenoaie
?ioi?oaoo, noaio i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a, oaeoi??a
aioeieneaeaioiiai caoenoo, ai?iiiaeueiiai noaoono a ne?iaaooe? e?ia?,
?ioia?e ??aeei? oa ia?ioeaeiiio nae?ao?. Iieacaia aeniea ?ioiiei?aaoth/a
aeoeai?noue oeiae?io ? e?cioeeio oa ae?aaeaia iaia?aiinoaa?e?coth/a ae?y
eiiieaeno i?e?iaeieo aioeieneaeaio?a. Aeei?enoaiiy eaca?ioa?ai??,
aoaeaoeaaiai ni?aaioo oa i?o?aoeeaeo ia i?noeaaiio ??ai? ni?eyei a?eueo
oaeaee?e e?ea?aeaoe?? yaeu caiaeaiiy. I?iaaaeaii anaa?/iee ii??aiyeueiee
aiae?c ?acoeueoao?a canoinoaaiiy o?aaeeoe?eieo ? cai?iiiiiaaieo niinia?a
oa?ai??, ui aeicaieeei anoaiiaeoe aenieo aoaeoeai?noue eiiieaeniiai
aeeoa?aioe?eiaaiiai e?eoaaiiy oa ?aaa?e?oaoe?eieo caoiae?a i?e aino?eo
caiaeueieo i?ioeanao uaeaiii-eeoeaai? ae?eyiee oa o?ii?/iiio
ia?aio?iaoiciiio ia?ioeo? o ae?oae. Cai?iiiiiaai? noaie e?eoaaiiy
ciaeoee oni?oia aeei?enoaiiy a ?yae? noiiaoieia?/ieo ee?i?e.

Eeth/ia? neiaa: ae?oe, uaeaiii-eeoeaaa ae?eyiea, caiaeuei? i?ioeane,
iaoiaaiac, e?eoaaiiy.

aiiioaoeey

Oea/aiei I.E. Iaoiaaiaoe/aneea iniaaiiinoe ainiaeeoaeueiuo i?ioeannia
/aethnoii-eeoeaaie iaeanoe o aeaoae e aeeooa?aioee?iaaiiua iiaeoiaeu e
eo ea/aieth.– ?oeiienue.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie aeieoi?a iaaeeoeeineeo iaoe ii
niaoeeaeueiinoe 14.01.22 – noiiaoieiaey.–Oe?aeineay iaaeeoeeineay
noiiaoieiae/aneay aeaaeaiey, Iieoaaa, 1998 a.

Aeenna?oaoeey iinayuaia aii?inai iaoiaaiaca e aeeooa?aioee?iaaiiiai
ea/aiey ino?uo ainiaeeoaeueiuo caaieaaaiee /aethnoii-eeoeaaie iaeanoe e
o?iie/aneiai ia?aioeiaoiciiai ia?ioeoa o aeaoae. A ?aaioa i?aaenoaaeaii
iiaia iai?aaeaiea a eco/aiee iaoaieciia ?acaeoey e ea/aiey
ainiaeeoaeueiuo i?ioeannia /aethnoii-eeoeaaie iaeanoe. Ii?aaeaeaiu
iniaaiiinoe nenoaiu eiioieoaoa, ninoiyiea i?ioeannia ia?aeeniiai
ieeneaiey eeieaeia, oaeoi?ia aioeieneaeaioiie caueou, ai?iiiaeueiiai
noaoona a nuai?ioea e?iae, ?ioiaie aeeaeeinoe e ia?ioeaeiii nae?aoa.
Iieacaia aunieay eiioiiei??aae?othuay aeoeaiinoue oeiaeeia e eecioeeia,
au?aaeaiiia iaia?aiinoaaeeece?othuaa aeaenoaea eiiieaena i?e?iaeiuo
aioeieneaeaioia. Eniieueciaaiea eaca?ioa?aiee, oaea?iaeiiai ni?aaioa e
ieoaoeeaea ia ianoiii o?iaia niinianoaiaaei aieaa auno?ie eeeaeaeaoeee
i?iyaeaiee ainiaeaiey. I?iaaaeai iiiainoi?iiiee n?aaieoaeueiue aiaeec
?acoeueoaoia eniieueciaaiey o?aaeeoeeiiiuo e i?aaeeiaeaiiuo niiniaia
oa?aiee, /oi iicaieeei onoaiiaeoue aunieoth yooaeoeaiinoue eiiieaeniiai
aeeooa?aioee?iaaiiiai ea/aiey e ?aaaeeeoaoeeiiiuo ia?ii?eyoee i?e ino?uo
ainiaeeoaeueiuo i?ioeannao /aethnoii-eeoeaaie iaeanoe e o?iie/aneii
ia?aioeiaoiciii ia?ioeoa o aeaoae. I?aaeeiaeaiiua noaiu ea/aiey iaoee
oniaoiia i?eiaiaiea a ?yaea noiiaoieiae/aneeo eeeiee.

Eeth/aaua neiaa: aeaoe, /aethnoii-eeoeaaay iaeanoue, ainiaeeoaeueiua
i?ioeannu, ea/aiea.

summary

P.I.tkachenko. Pathogenetic peculiarities of inflamatory processes of
maxillofacial area in children and differentiated approaches to its
treatment. – Manuscript.

The thesis is submited for the degree of a Doctor of medicine on the
speciality 14.01.22 – stomatology. – Ukrainian medical stomatological
academy, Poltava, 1998.

The dissertation is devoted to the problem of pathogenesis and
differentiated treatment of acute inflamatory deseases of maxillofacial
area and chronic parenchymatous parotitis in children. In the work there
was developed the new direction in the study of mechanisms of
development and treatment of the inflamatory processes in maxillofacial
area. There were determined the peculiarities of the immunity system,
the state of lipid peroxideoxidation processes, factors of antioxidant
protection, hormonal status in blood serum, oral liquid and parotid
secretion. There were shown the high immunocorrective effectiveness of
thymalin, lysocim, the expressed membrane-stabilizing action of natural
antioxidant complex. The use of laser therapy, carbon sorbent and
nitacidis at the local level promoted the more rapid liquidation of
inflamatory manifestations. There was conducted the many-sided
comparative analysis of the results of the use of traditional and the
proposed methods of therapy. That allowed to find out the high
effectiveness of complex differentiated treatment and rehabilitative
measures in acute inflamatory processes of maxillofacial area and
chronic parenchymatous parotitis in children. The proposed schemes of
therapy found the successful employment in several dental clinics.

Key words: children, maxillofacial area, inflamatory process,
pathogenesis, treatment.

Aeneiaethth iiaeyeo ni?a?ia?oieeai OeIAeE OINA oa Iieoaanueei? i?nueei?
aaeoa??ieia?/ii? eaai?aoi??? ca ni?eyiiy o i?iaaaeaii? aeine?aeaeaiue.

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