?INOEOOO IAAe?AO??? AEOOA?NOAA ? A?IAEIEIA??

AEAAeAI?? IAAeE*IEO IAOE OE?A?IE

NA?A??IEI NA?A?E AIEIAeEIE?IAE*

OAeE 618.3+616-053.1+616-053.31:614.876

INIAEEAINO? ?IOIIEIA?*IIAI NOAOONO NENOAIE IAOE-IEIAe-IIAIIA?IAeAEAIEE O
AAA?OIEO A OIIAAO Ae?? IAEEO AeIC ?AAe?AOe??

14.01.01 — Aeooa?noai ? a?iaeieia?y

A a o i ? a o a ? a o

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

EE?A — 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a ?inoeooo? iaae?ao???, aeooa?noaa ? a?iaeieia??
Aeaaeai?? iaaee/ieo iaoe Oe?a?ie

Iaoeiaee ea??aiee- aeieoi? iaaee/ieo iaoe, i?ioani?

Aeaoeaae/ Aaeaioeia ?aaeieei?aia

?inoeooo iaae?ao???, aeooa?noaa ? a?iaeieia?? AII Oe?a?ie

caa?aeoth/a aeooa?nueeiai a?aeae?eaiiy aeno?aaai?oaeueieo

caoai?thaaiue aaa?oieoIo?oe?ei? iiiiaioe:- aeieoi? iaaee/ieo iaoe,
i?ioani? /eai-ei?aniiiaeaio IAI

? AII Oe?a?ie Noaiaie?anueea Aaeeia Einoyioei?aia

Iaoe?iiaeueiee iaaee/iee oi?aa?neoao

i?ioani? eaoaae?e aeooa?noaa ? a?iaeieia?? N 1- aeieoi? iaaee/ieo
iaoe, i?ioani?

Eenyiee Ieeiea ?aaiiae/

Ea??aiee eaai?aoi??? ?ioiieia?? ?inoeoooo iae?io??o?a??

AII Oe?a?ie ?i. aeaae. A.I. ?iiiaeaiiaaI?ia?aeia i?aai?caoe?y
Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i.

I.E.Ooieea IIC Oe?a?ie, eaoaae?a aeooa?noaa ? a?iaeieia??

N 1

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 22 ” a?oaeiy 1998 ?. i 13-00aiae.
ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae.26.553.01 ii caoenoo
aeena?oaoe?e ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaoe ca
niaoe?aeueiinoyie “Iaae?ao??y”, “Aeooa?noai ? a?iaeieia?y” i?e ?inoeooo?
iaae?ao???, aeooa?noaa ? a?iaeieia?? AII Oe?a?ie (254050, i. Ee?a — 50,
aoe. Iaio?euenueeiai, 8).

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? ?inoeoooo
iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie (254050, i. Ee?a — 50,
aoe. Iaio?euenueeiai, 8).

Aaoi?aoa?ao ?ic?neaiee “ 19 ” eenoiiaaea 1998 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Eaaoi?ia E.A.CAAAEUeIA OA?AEOA?ENOEEA
?IAIOE

Aeooaeuei?noue oaie. Eaoano?ioa 1986 ?ieo ia *i?iiaeeuenuee?e AAN
i?ecaaea aei ?aae?iaeoeaiiai caa?oaeiaiiy cia/ieo ii ieiu? oa?eoi??e ?
aieeao ?aae?aoe?eieo oaeoi??a ia ianaeaiiy, yea i?iaeeaa? ia oeeo
oa?eoi??yo (TH.I.Ni?aeaiei, 1991; A.A. Aa?ueyooa?, 1995). Iniaeeao
o?eaiao aeeeeea? caei?ia’y aaa?oieo ae?iie oa ?o iioiinoai, a?ae yeiai
caeaaeeoue iaeaooi? iaoe??, ui iaoiiaeth? iaiao?aei?noue aea/aiiy
i?ieiiaiaaiiai aieeao iaeeo aeic ?aae?iaeoeaiiai aei?ii?ithaaiiy ia
i?aai?ci aaa?oii?, ieiaea ? iiaiia?iaeaeaiiai. Oey i?iaeaia ye a
oai?aoe/iiio, oae ? a i?aeoe/iiio ieai? ? iaei??th c i?ia?aeieo a
no/aniiio aeooa?noa? ? iaaee/i?e ?aae?ieia??.

I?ney aaa??? ia *AAN ca?aeii c aeaieie e?oa?aoo?e (A.I.Eoeueyiiaa e
niaao., 1992; A.E.E?aniiiieueneee e niaao. 1992; A.I.Aaioeeianeee, 1993;
A.A.Eieii?eoeaaa, E.A.Ae?aeaiei, 1993; A.?.Aeaoeaae/, E.A.Aooiai, 1993)
a?aei?/a?oueny c?inoaiiy oaeeo oneeaaeiaiue aaa?oiino? ? iieia?a, ye
aanoice, aiai??, iaaeiiooaaiiy, cao?eiea ?icaeoeo ieiaea, e?iaioa/?, a
oaeiae ii?ooaiiy ?aiiuei? iinoiaoaeueii? aaeaioaoe?? iiaiia?iaeaeaieo.

I?e/eie ?inoo oeeo oneeaaeiaiue ? iaoiaaiac ?o ?icaeoeo caeeoathoueny
iaaeinoaoiuei onoaiiaeaieie. Ia?niaeoeaiei iai?yieii iiooeo ? aecia/aiiy
?o iaoiaaiaco aeyaeeinue aea/aiiy ?ie? ?ioiieia?/ieo ?aaeoe?e, aaeaea
ii?ooaiiy ?o ooieoe?iioaaiiy ? iaoiaaiaoe/iei noano?aoii oi?ioaaiiy
niiaoe/ii? iaoieia?? (A.I. *a?ieoia oa ni?aaao., 1991; A.A. *oiae oa
ni?aaao., 1996). ?ioiia nenoaia iaea?eueo /ooeeaa aei ae?? ?ii?coth/i?
?aae?aoe?? (O.I. Iiiianueea, 1993), oiio aieea *i?iiaeeuenueei?
eaoano?ioe a on?e nai?e aaaaoia?aiiino? iicia/eany ia ?ioiieia?/ieo
iieacieeao. Aeeiai?ea oeeo iieaciee?a a?ae?aco i?ney aaa??? ? /a?ac 12
?ie?a ia? nai? iniaeeaino?, ye? iaoiiaeai? aeicith ii?ii?iaiiy, oi/a ?
ia caaaeaee c /?oeith ei?aeyoe??th, iayai?noth iiia?aaeiuei? oa
noiooiuei? niiaoe/ii? iaoieia??, nioe?aeueieo, aeiiii?/ieo, iiaooiaeo ?
ae?iaie/eo oaeoi??a.

I?iaeaia iaoa?einueei-ieiaeiaeo ?ioiieo aca?iia?aeiinei c o?aooaaiiyi
ciie ?aae?iaeoeaiiai caa?oaeiaiiy aea/aia iaaeinoaoiuei. Ia iaio
aaaeeeaith ? i?iaeaia ii?iae?caoe?? ?ioiieia?/ieo ii?ooaiue a nenoai?
iaoe-ieiae-iiaiia?iaeaeaiee aeey noai?aiiy a?eueo ni?eyoeeaeo oiia
ia?aa?ao aaa?oiino? ? ?icaeoeo ieiaea.

A aeinooii?e e?oa?aoo?? ie ia cono??ee ?ia?o, ye? aena?oethaaee a noai
aooi?ioiieo i?ioean?a (iayaiino? aooiaioeo?e aei yaea?ieo eiiiiiaio?a
ee?oeie, ??aiy aioeoinoie?i?aeieo aioeo?e) ? oei?/ii? aeoeaiino?
ne?iaaoee e?ia? a caeaaeiino? a?ae aeice iaeiie/aiiy ?aae?iioee?ae?a.

E??i oiai, a e?oa?aoo?? a?aenooi? ?iaioe ii ?ic?iaoe? ?ioiieia?/iiai
ianii?oo iiaiia?iaeaeaiiai a?ae iaoa??a, ye? iino?eii i?iaeeaathoue a
oiiaao o?eaaeiai aieeao iaeeo aeic ?aae?aoe??. I?ae oei, aea/aiiy oeeo
ieoaiue iaiao?aeii aeey nai?/aniiai i?iaaaeaiiy
e?eoaaeueii-i?io?eaeoe/ieo caoiae?a, ui aeicaieeoue cieceoe /anoioo
oneeaaeiaiue c aieo iaoa?? ? ieiaea o oaeeo aaa?oieo.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa aeeiiaia a?aeiia?aeii c ieaiii iaoeiai-aeine?aeieo ?ia?o
?inoeoooo IAA AII Oe?a?ie ? ? o?aaiaioii eiiieaenii? oaie “Aea/eoe
aeeiai?eo noaio caei?iay ?aae?aoe?eii iino?aaeaeaeiai ianaeaiiy Oe?a?ie
c iiceoe?? ?aeeii? a?ieia?/ii? nenoaie iaoe-ieaoeaioa-ieiae-aeeoeia” (?
aea?aeaaii? ?a?no?aoe?? 01.96 E 016153), yea aoiaeeoue a Aea?aeaaio
i?ia?aio iaoeiai-aeine?aeieo ?ia?o uiaei i?i?i?caoe?? iane?aee?a aaa???
ia *AAN (? 01.91.00.42252).

Iaoa aeine?aeaeaiiy. Iaoeiai iaa?oiooaaoe oa ?ic?iaeoe eiiieaen
e?eoaaeueii-i?io?eaeoe/ieo caoiae?a, ni?yiiaaieo ia ei?aeoe?th ?ioiieo
ii?ooaiue a iaoa?einueei-ieiaeiaiio eiiieaen? o aaa?oieo ?aa?iia aaa???
ia *AAN c o?aooaaiiyi caa?oaeiaiiy Cs ciie i?iaeeaaiiy.

Caaea/? aeine?aeaeaiiy:

1. Aea/eoe ia?aa?a aaa?oiino?, iieia?a, noai ieiaea ? iiaiia?iaeaeaiiai
a oiiaao o?eaaei? ae?? iaeeo aeic ?aae?aoe?? c o?aooaaiiyi ciie
?aae?iaeoeaiiai caa?oaeiaiiy ? aeice iaeiie/aiiy ?aae?iioee?ae?a.

2. Aeaoe ioe?ieo noaio nenoaie ?ioiiaaiaca iaoa?einueei-ieiaeiaiai
eiiieaena o aaa?oieo ?aa?iia aaa??? ia *AAN.

3. C’ynoaaoe noai oei?/ii? ne?iaaoeiai? aeoeaiino?, iayaiino?
aooiaioeo?e aei yaea?ieo eiiiiiaio?a ee?oeie oa ??aiy aioeoinoie?i?aeieo
aioeo?e o aeaiiai eiioeiaaioo aaa?oieo oa ?o iiaiia?iaeaeaieo.

4. Aecia/eoe aca?iicaycie i?ae iieacieeaie ?ioiiiai noaoono
iaoa?einueei-ieiaeiaiai eiiieaeno ? iniaeeainoyie aeooa?nueeeo ?
ia?eiaoaeueieo oneeaaeiaiue.

5. ?ic?iaeoe ?ioiieia?/iee ianii?o iiaiia?iaeaeaiiai ia iniia?
io?eiaieo aeaieo.

6. ?ic?iaeoe iaoiaee ei?aeoe?? ii?ooaiue ?ioiieia?/iiai noaoono nenoaie
iaoe-ieiae-iiaiia?iaeaeaiee o aaa?oieo eiio?ieueiaaieo ii ?aae?aoe??
oa?eoi??e ? aea/eoe ?o aoaeoeai?noue.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. Aeaia ia’?eoeaia ioe?iea noaio
caei?ia’y aaa?oieo, ye? i?iaeeaathoue ia ?aae?aoe?eii caa?oaeiaieo
oa?eoi??yo, aecia/aia /anoioa, no?oeoo?a ? iniiai? i?e/eie aeooa?nueeeo
? ia?eiaoaeueieo oneeaaeiaiue a caeaaeiino? a?ae aeice iaeiie/aiiy
?aae?iioee?ae?a ? ciie ?aae?iaeoeaiiai caa?oaeiaiiy Cs 137. Aia?oa o
oaeeo aaa?oieo aea/aii oa ioe?iaii noai ?ioiieia?/iiai noaoono nenoaie
iaoe-ieiae-iiaiia?iaeaeaiee oa aeae?eaii a?oio iiaiia?iaeaeaieo c
aenieei nooiaiai ?eceeo ?icaeoeo aooi?ioiii? iaoieia?? a iaeaooiueiio.
?ic?iaeaii ?ioiieia?/iee ianii?o iiaiia?iaeaeaiiai. Aia?oa iaoiaeii
ei?aeyoe?eiiai aiae?co aeyaeai? ca’ycee i?ae ??aiai aioeoinoie?i?aeieo
aioeo?e ? /anoioith aeieeiaiiy oneeaaeiaiue ia?eiaoaeueiiai ia??iaeo o
aeaiiai eiioeiaaioo aaa?oieo. Iaoeiai iaa?oioiaaii ? ?ic?iaeaii
iaoiaaiaoe/ii iaoiiaeai? aa??aioe ei?aeoe?? ?ioiieia?/ieo ii?ooaiue
iaoa?einueei-ieiaeiaiai eiiieaeno o aaa?oieo ?aa?iia aaa??? ia *AAN.
Iieacaia aeioe?euei?noue i?ecia/aiiy ?ioiiei?eaoth/eo i?aia?ao?a,
aioeieneaeaio?a, aeacaa?aaaio?a, aeaei?ii?aio?a oa aioeeiaaoeyio?a a
i?io?eaeoeoe? ia?eiaoaeueii? iaoieia?? o aaa?oieo, ye? i?iaeeaathoue a
ciiao ?aae?aoe?eiiai caa?oaeiaiiy.

I?aeoe/ia cia/aiiy io?eiaiieo ?acoeueoao?a. Ia iniia? iiaeeaeaiiai
eiiieaeniiai aeine?aeaeaiiy nenoaie ?ioi?oaoo iaoa?einueei-ieiaeiaiai
eiiieaeno aecia/aii aeiaeaoeia? e?eoa??? ae?aaiinoeee aooi?ioiii?
iaoieia?? o iiaiia?iaeaeaieo a?oie ?aae?aoe?eiiai ?eceeo. ?ic?iaeaii
aeiaeaoeiaee eiiieaen ianoaaeaiiy aaa?oieo ?aa?iia aaa??? ia *AAN,
iai?aaeaiee ia aeyaeaiiy oaeoi??a ?eceeo aeieeiaiiy aeooa?nueeeo ?
ia?eiaoaeueieo oneeaaeiaiue. Cai?iiiiiaaii iaoiae
e?eoaaeueii-i?io?eaeoe/ieo caoiae?a a caeaaeiino? a?ae oa?aeoa?o
?ioiieia?/ieo ii?ooaiue, iayaiino? aioeoinoie?i?aeiiai neiae?iio, ui
ni?ey? cieaeaiith aeooa?nueeeo ? ia?eiaoaeueieo oneeaaeiaiue.

?acoeueoaoe aeine?aeaeaiiy ai?iaaaeaeai? a i?aeoeeo ?iaioe ?iaeiiii?/ieo
caeeaae?a Ee?anueei?, Aeiiaoeueei?, *a?i?a?anueei?, AEeoiie?nueei? oa
Eoaainueei? iaeanoae.

Oai?aoe/i? iieiaeaiiy oa i?aeoe/i? ?aeiiaiaeaoe?? aeei?enoiaothoueny ia
eo?nao i?aeaeuaiiy eaae?o?eaoe?? aeooa??a-a?iaeieia?a Ee?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe IIC Oe?a?ie, eo?nao
?ioi?iaoe?? ? noaaeoaaiiy i?e ?inoeooo? iaae?ao???, aeooa?noaa oa
a?iaeieia?? AII Oe?a?ie.

Iniaenoee aianie caeiaoaa/a:

1. I?iaaaeaii ee?i?ei-noaoenoe/iee aiae?c ia?aa?ao aaa?oiino? ? iieia?a,
noaio ieiaea ? iiaiia?iaeaeaiiai a caeaaeiino? a?ae ciie caa?oaeiaiiy Cs
137 (5609 ?noi??e iieia?a).

2. Ee?i?/ia eiiieaenia ianoaaeaiiy 150 aaa?oieo, ye? iino?eii
i?iaeeaathoue a oiiaao ae?? iaeeo aeic ?aae?aoe??, oa 50 caei?iaeo
ae?iie c oiiaii “/enoeo” oa?eoi??e.

3. Caaacia/aii aecia/aiiy a?oi aaa?oieo aeey aeine?aeaeaiiy nenoaie
?ioi?oaoo.

4. E?eoaaiiy aaa?oieo ca cai?iiiiiaaiei eiiieaenii i?io?eaeoe/ieo ?
e?eoaaeueieo caoiae?a c iiaeaeueoith ioe?ieith eiai aoaeoeaiino?.

5. Aiae?c io?eiaieo aeaieo oa ?o iaoaiaoe/ia ia?iaea.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee aeena?oaoe??
i?aaenoaaeai? ia eiioa?aioe?? iieiaeeo a/aieo Oe?a?ie (A?iieoey, 1995);
I?aeia?iaeiiio neiiic?oi? “Immunology of reproduction” (Ee?a, 1996);
iaoeiaeo eiioa?aioe?yo “Aeieia?y ? ethaeeia” (Ee?a, 1995, 1996, 1997);
Anana?oiueiio eiia?an? aeooa??a-a?iaeieia?a (FIGO) — Aeai?y, Eiiaiaaaai
(1997); eiioa?aioe?? iieiaeeo a/aieo ?inoeoooo iaae?ao???, aeooa?noaa oa
a?iaeieia?? AII Oe?a?ie (Ee?a, 1997).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 10 ?ia?o, ?c ieo 3
— o i?ia?aeieo aeo?iaeao, 2 — o ca??ieeao iaoeiaeo i?aoeue, 5 — o oacao
iaoeiaeo eiioa?aioe?e, eiia?an?a.

Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aena?oeaia ia 147 noi??ieao
iaoeiiieniiai oaenoo ? neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e,
/ioe?ueio ?icae?e?a aeanieo aeine?aeaeaiue, aiae?co oa ocaaaeueiaiiy
io?eiaieo ?acoeueoao?a, aeniiae?a ? i?aeoe/ieo ?aeiiaiaeaoe?e. Iieaae/ee
e?oa?aoo?e i?noeoue 248 aeaea?ae. ?iaioa ?ethno?iaaia 27 oaaeeoeyie ? 5
iaethieaie, ye? aeeeaaeai? ia 22 noi??ieao.

CI?NO ?IAIOE

I’a?eo oa iaoiaee aeine?aeaeaiiy. Aeey ae??oaiiy iinoaaeaieo caaaeaiue
i?iaaaeaii ee?i?ei-noaoenoe/iee aiae?c /anoioe ? oa?aeoa?o aeooa?nueeeo
? ia?eiaoaeueieo oneeaaeiaiue, noaio caei?ia’y o 5609 aaa?oieo aeaio
?aa?ii?a AEeoiie?nueei? iaeano? c ??aiai caa?oaeiaiiy ii Cs 137 a?ae 15
aei 40 Ku/km2 (Ia?iaeeoeueeee ?aeii — 2 ciia), oa a?ae 5 aei 15 Ku/km2
(Ia?ooeueeee ?aeii — 3 ciia). Eiiieaenii ianoaaeaii 150 aaa?oieo, ye?
iino?eii iaoeathoue a ?aae?aoe?eii eiio?ieueiaaieo ?aeiiao (iniiaia
a?oia: 65 — ?c 2 ciie, 85 — ?c 3-?), oa 50, ye? i?iaeeaathoue o
a?aeiinii “/enoeo” ?aeiiao Ee?anueei? iaeano? (i. ssaioei) — a?oia
ii??aiyiiy.

E??i caaaeueiiai ee?i?ei-eaai?aoi?iiai oa ?ino?oiaioaeueiiai ianoaaeaiiy
a eiaei?e a?oi? aea/aee iieacieee ee?oeiiiai oa aoii?aeueiiai ?ioi?oaoo
iaoa?einueei-ieiaeiaiai eiiieaeno. Aeine?aeaeaiiy i?iaiaeeee a
aeeiai?oe? aaa?oiino?, aei ? i?ney e?eoaaiiy. ?aae?iiao??th i?aai?cio
iaoa?? i?iaiaeeee ca aeiiiiiaith e?/eeueieea aei??thaaiiy ethaeeie (EAE
— Scaner 2M) ia?aeaeueii c niaeo?iiao???th e?ia? ae?iee ? noaeei
ioiiaeie. Iaie aecia/aii cia/i? eieeaaiiy ieoiii? aeoeaiino? ?cioii?a o
aaa?oieo iaeiiai ? oiai ae ?aa?iia. Eieeaaiiy ai?noo ?aae?iioee?ae?a
(Cs 134, Cs 137, K 40) a e?ia? iaoa?? aoei a iaaeao 1,5 — 2,1 Ae/ea, a
e?ia? noaeei ioiiaeie — 1,0 — 1,7 Ae/ea. A ieaoeaio? ii aeaiei
TH.A.Aeaaeaeiai? (1996), ai?no ?aae?iioee?ae?a aoa cia/ii aeuei ?
eieeaaany a iaaeao 1,2 — 4,9 ? a?eueoa Ae/ea, ui na?ae/eoue i?i cao?eieo
inoaii?o a ieaoeaio? aiane?aeie ci?i ?? no?oeoo?ieo iniaeeainoae.

E?euee?niee ai?no iniiaieo ?aaoeyoi?ieo noaiiioeyoe?e O- ?
A-e?ioioeeo?a, NK-ee?oei aecia/aee iaoiaeii aeaieieuei?iai? i?ioi/ii?
oeoi?eiao??? ca aeiiiiiaith iaai??a iiiieeiiaeueieo aioeo?e i?ioe
ia?ea??a e?ioioeeo?a oaeia??a-?iaeoeoi??a (CD4+),
noi?ani??a-oeeoioienee?a (CD8+), O-e?ioioeeo?a (CD3+), A-e?ioioeeo?a
(CD19+), iaoo?aeueieo e?ea??a (CD16+/56+) ae?iaieoeoaa o??ie Becton
Dikason NOA. ??ai? ?ioiiaeiaoe?i?a A, G, M — oeyoii ?aae?aeueii?
?ioiiaeeooc?? o aae? ii Manchini et al. (1965). Ioe?ieo oaaioeeoa?ii?
aeoeaiino? iaeo?io?eueieo a?aioeioeeo?a cae?enithaaee ca iaoiaeii
i?ioi/ii? oeeoioeoi?eiao???; ai?no oee?eoethth/eo ?ioiieo eiiieaen?a
(Oe?E) aecia/aee niaeo?ioioiiao?e/ii i?ney inaaeaeaiiy ?o c ne?iaaoie
iie?aoeeaiae?eieai (6 % IAA).

Aioeoinoie?i?aei? aioeo?ea aecia/aee noaiaea?oieie iaoiaeaie
?ioiioa?iaioiiai aiae?co c aeei?enoaiiyi iaai?o ?aaeoea?a SIA ANTI
Cardiolipin (Sigma, USA) ca i?ioieieii, ui aeiaea?oueny aei iaai?o.
Iayai?noue aooiaioeo?e aei yaea?ieo eiiiiiaio?a ee?oeie — iaoiaeii
oaa?aeioaciiai ?ioiieia?/iiai aiae?co, a oaeiae a e?euee?ni?e ?aaeoe??
ca’ycoaaiiy eiiieaiaioo a i?e?iiinoaiiaoe?. Oei?/io ne?iaaoeiao
aeoeai?noue (ONA) aecia/aee ii caeaoiino? aeine?aeaeaieo c?ace?a
?iaeoeoaaoe aeic??aaiiy e?ioioeeo?a naeac?iee oeiaeoiiiaaieo ieoae. Ca
oeo? ONA i?eeiaee inoaii? ?icaaaeaiiy ne?iaaoee, ui iaoiiaeth? 50 %
?aaeoeoe?th /enea niiioaiieo ?icaoie i?e aeei?enoaii? aioee?ioioeeoa?ii?
ne?iaaoee. Aeine?aeaeaiiy i?iaiaeeee a eaai?aoi??? ?ioiieia?? ?
?aae?ieia?? ?inoeoooo IAA AII Oe?a?ie, o a?aeae?e? iieaeoey?ieo iniia
naieioeee ?inoeoooo a?io?i?? AI Oe?a?ie oa II «A???a» i?e ?inoeooo?
o?ceee.

Aeey ioe?iee noaio oa oa?aeoa?o na?oeaai? ae?yeueiino? ieiaea
i?iaiaeeee ea?ae?ioieia?ao?/ia aeine?aeaeaiiy c aeei?enoaiiyi
iano?aniaiai oanoo ia a?iiii?oi?? “BMT 9141” o??ie RFT. Aeai?
ea?ae?ioieia?aie ioe?ithaaee ca oeaeith W. Fisher (1976). Ioe?iea noaio
oaoiieaoeaioa?iiai eiiieaeno i?iaiaeeeanue ca aeiiiiiaith
oeueo?acaoeiai? aoia?ao?? oa ieaoeaioia?ao?? ia aia?ao? “Aloca — 260”
(ssiii?y).

Aiae?c ia?aa?ao aaa?oiino?, iieia?a oa i?neyiieiaiaiai ia??iaeo o
ae?iie ?aa?iia aaa??? ia *AAN aoei i?iaaaeaii c o?aooaaiiyi noaio iaoa??
oa ieiaea, ciie caa?oaeiaiiy Cs 137, ci?i a nenoai? ?ioi?oaoo
iaoa?einueei-ieiaeiaiai eiiieaeno.

Noai iiaiia?iaeaeaieo ioe?ithaaee ca aeaieie ee?i?/iiai ianoaaeaiiy
iae?aco i?ney ia?iaeaeaiiy (ia 1-e oa 5-e oaeeei?) ca 10 aaeueiith
oeaeith Aiaa?, aeaieie o?ce/iiai ?icaeoeo oa iniaeeainoyie ia?aa?ao
?aiiueiai iaiiaoaeueiiai ia??iaeo.

Noaoenoe/ia ia?iaea ?acoeueoao?a aeine?aeaeaiue i?iaiaeeeanue ia IAII.
On? oeeo?ia? aeai? ia?iaeai? iaoiaeii aa??aoe?eii? noaoenoeee
(E.N.Eaieinueeee, 1964; I.O.?aeeoeeee, 1967). Aeey ioe?iee
aeinoia??iino? (?) ??cieoe? i?ae a?oiaie iieaciee?a aeei?enoiaoaaee
t-e?eoa??e Nouethaeaioa (O. Oaie, 1972). A ?iaio? aoa i?eeiyoee ??aaiue
?iia??iino? ?0,05. Ioe?ieo ??cieoe? a ?ici??ao aeieae (a?aenioe?a)
aecia/aee ca e?eoa???i (eooiaiai ia?aoai?aiiy O?oa?a).

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy.

C iaoith aeyaeaiiy caeiiii??iinoae ae?? ia i?aai?ci aaa?oieo
aeno?aiaeueii? neooaoe?? a ia??iae iaeneiaeueiiai ?aae?aoe?eiiai
iaaaioaaeaiiy oa a ianooiiiio iaeeo aeic ?aae?aoe?? i?iaaaeaii
ii??aiyeueiee aiae?c aeeiai?ee noaio ?o caei?ia’y, iniaeeainoae ia?aa?ao
aaa?oiino? oa iieia?a ia oa?eoi??yo c ??ciei ??aiai caa?oaeiaiiy ii
oeac?th. Anoaiiaeaii, ui /anoioa oneeaaeiaiue aaa?oiino? ? iieia?a o
ae?iie ?aa?iia aaa??? c caa?oaeiaiiyi Cs 40 Ku/ei2 ? aeua nooo?ai
ia?aaeuo? iieacieee ii ?aeiio, aea u?euei?noue caa?oaeiaiiy a?oioo
cia/ii ieae/a (aei 15 Ku/ei2). Oea na?ae/eoue i?i iani?eyoeeaee aieea
?aae?aoe?eieo oaeoi??a ia ia?aa?a aaa?oiino? o ae?iie, ui iino?eii
iaoeathoue a eiioai?iiaaiiio ?aa?ii? (?en. 1). *anoith iaoieia??th aoee
i?ci? aanoice (29,23%, 17,65% i?ioe 8,0% a a?oi? ii??aiyiiy, ?0,05).
Caa?ica ia?a?eaaiiy aaa?oiino? a?aecia/aia o 36,92 %, 23,53 % ? 12,0 %
a?aeiia?aeii. O aaa?oieo ?aa?iia aaa??? ia *AAN cia/ii /ano?oa a
ii??aiyii? c “/enoeie” oa?eoi??yie cono??/a?oueny cao?eiea ?icaeoeo
ieiaea (19,7%, 16,1% ? 6,0%, ?0,05) oa eiai a?iien?y (39,3%, 34,7% ?
4,0%, ?0,05), ui iia’ycaii c iani?iiiaei?noth ai?iiiaeueii? ooieoe??
ieaoeaioe, ?? ?ioiieia?/iiai aa?’??o oa iaoaaie?/ieie ii?ooaiiyie a
iaoa?einueei-ieiaeiaiio eiiieaen?. Ia?aae/ani? iieiae o aeaiiai
eiioeiaaioo ae?iie cono??/athoueny o 2,2 ?ace /ano?oa, i?ae o aaa?oieo
a?oie ii??aiyiiy (?0,05). Anoaiiaeaia ei?aeyoeaia caeaaei?noue /anoioe
aeooa?nueei? iaoieia?? ? ??aiy caa?oaeiaiiy Cs 137 ciie i?iaeeaaiiy
(r = +0,7, ?0,05), yea ia caaaeaee ei?aethaaea c aeicith ii?ii?iaiiy.

I?e aiae?c? niiaoe/ii? caoai?thaaiino? aaa?oieo aecia/aii, ui iaea?eueoo
ieoiio aaao ia? cae?ciaeao?oeeoia aiai?y, cia/ia c?inoaiiy yei?
a?aei?/a?oueny o an?o a?oiao ianoaaeaieo (?0,05). Ca?eueoeeanue oaeiae
/anoioa i??eiiao?eo?a, ?ani??aoi?ieo ?ioaeoe?e, ui iiaea aooe iia’ycaii
c i?eai?/aiiyi nenoaie ?ioi?oaoo, iniaeeai o ae?iie c ?? ciie
?aae?aoe?eiiai eiio?iey. O?iaai?oaeueia ?ioaeoe?y a naith /a?ao,
i?eaiaeeoue aei ?inoo /anoioe ?ioaeoe?eii-caiaeueii? iaoieia??
i?neyiieiaiaiai ia??iaeo ? oo?iaiiai ?io?eoaaiiy ieiaea ?
iiaiia?iaeaeaiiai. Ne?ae a?aei?oeoe c?inoaiiy a 2,5 — 3 ?ace /enea
iae?i-oee?eoeyoi?ieo anoai?e, ye? i?ioyaii aaa?oiino? i?ia?anothoue,
i?eeiath/e a ?yae? aeiaaee?a iani?eyoeeaee ia?aa?a c
aaaaoi-a?noea?aeueieie e?ecaie.

Na?aae oneeaaeiaiue iieia?a ne?ae a?aecia/eoe ianai?/ania a?aeoiaeaeaiiy
iaaeieiie?aeieo aiae (18,46 %, 16,47 % i?ioe 10,0 %, ?0,05), neaae?noue
?iaeiai? ae?yeueiino? (21,54 %, 17,65 % ? 6 %, ?0,05), e?iaioa/? (15,38
%, 11,76 % i?ioe 4 % a a?oi? ii??aiyiiy). *anoioa ano?en??
iiaiia?iaeaeaieo neeaea 39,7 % ? 6,0 % a?aeiia?aeii (?0,05). Oeyoii
iia?aoe?? eana?aaa ?icoeio ?ic?iaeaeaii 16,5 % ?

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000000000000000000000000000000000000Oaaeeoey 1

Noai nenoaie ?ioi?oaoo iaoa?einueei-ieiaeiaiai eiiieaeno o aaa?oieo a
oiiaao ae?? iaeeo aeio ?aae?aoe?? (?? iieiaeia aaa?oiino?)

Aaa?oi? ae?ieeIiaiia?iaeaeai? (ioiiaeiia e?ia) Iieaciee nenoaie
?ioi?oaoo2 ciia3 ciiaA?oia ii??aiyiiy2 ciia3 ciiaA?oia
ii??aiyiiyT-e?ioioeeoe, %51,24±1,98*
**58,17±2,4459,87±3,7653,8±1,952,71±2,8355,19±1,7B-e?ioioeeoe,
%10,82±0,98*12,61±2,0314,83±1,5614,48±2,01*17,14±1,8719,4±1,38NK-ee?oeie
, %9,23±1,68*9,89±2,5114,34±1,7312,48±1,7*14,29±1,1818,91±2,34T-oaeia?e
(CD4+), %39,6±2,5239,78±1,6445,82±2,631,2±1,8*33,74±1,4936,8±2,1T-noi?
(CD8+),
%30,1±2,89*32,46±2,78*43,54±3,0823,9±2,42*24,56±1,1*29,72±1,21T-oaeia?e/
T-noi?ani?e1,35±0,11*1,23±0,06*1,01±0,091,34±0,11,3±0,071,2±0,08Ig G,
a/e9,25±0,4*9,97±0,69*12,06 ±0,819,04 ±0,45*10,2±0,22*11,1±0,4Ig A,
a/0,82±0,130,91±0,081,25±0,110,02±0,005*0,023±0,008*0,002±0,003Ig M,
a/e0,83±0,12*0,96±0,041,17±0,090,19±0,010,23±0,020,1±0,09Oaaioeeoa?ia
/enei52,93±4,47* **63,27±2,43*78,92±3,2833,65±5,29*
**63,27±2,4376,73±4,36Oaaioeeoa?iee ?iaeaen526,87±23,84*
**618,8±23,48*776,42±17,31590,43±8,06* **603,8±18,49624,4±22,65Oe?E,
iae. iio.u?eueiino?269,0±8,07* **201,0±9,5*125,0±6,9175,0±9,4*
**152,0±7,0*122±8,3Aioeioeeaa?i? aioeo?ea, %18,46*16,476,026,56* **15,29
*4,0Aioeoinoie?i?aei? aioeo?ea, %47,69* **30,59*8,0I?ei?oea. * —
??cieoey c a?oiith ii??aiyiiy aeinoia??ia (p < 0,05) ** - ??cieoey i?ae iieacieeaie aaa?oieo 2 oa 3 ciie caa?oaeiaiiy Cs aeinoia??ia (p < 0,05) 17,0 % ae?iie, a a?oi? ii??aiyiiy eana?aaiai ?icoeio ia aoei. Ia?eiaoaeueia nia?oi?noue caeeoa?oueny aenieith ? neeaaea? a?aeiia?aeii 27,0 i/ii, 17,7 i/ii. Ne?ae a?aei?oeoe aenieo /anoioo o ii?iae?eue ?aa?iia aaa??? ia *AAN i?neyiieiaiaeo ai?eii-naioe/ieo caoai?thaaiue. Oae, iae/ano?oa cono??/aeenue oae? oneeaaeiaiiy ye aiaeiiao?eo (5 %, 3,52 % ? 2,0 % a?aeiia?aeii), noa?iaiethoe?y iaoee (15,38 %, 10,59 % ? 4,0 %). Aiae?c /anoioe ? no?oeoo?e i?neyiieiaiaeo oneeaaeiaiue iieacaa, ui inoaii? a?eueoa i?ae a 2,5 ?ace /ano?oa a?aei?/athoueny i?ney ia?aae/anieo iieia?a (?0,05). Ee?i?/i? niinoa?aaeaiiy ca ia?aa?aii iaiiaoaeueiiai ia??iaeo o ae?oae a?ae iaoa??a, ye? iaoeathoue ia caa?oaeiaieo oa?eoi??yo, iieacaa, ui ia??iae aaeaioaoe?? iaa a?aeoeeaiiy a?ae ii?iaeueiiai ia?aa?ao (cieaeaiiy i’yciaiai oiiono, ?aoeaen?a, ii?ooaiiy iiceiaiai e?iaiia?ao, iiaoi?ia iaae?iiy iane o?ea oa ?i.) o 2,5 ?ace /ano?oa, i?ae o ae?oae iaoa??a a?oie ii??aiyiiy. Oaeei /eiii, o aaa?oieo, ye? iino?eii iaoeathoue ia ?aae?aoe?eii caa?oaeiaieo oa?eoi??yo c aeinoaoiuei aenieith /anoioith cono??/athoueny aeooa?nuee? ? ia?eiaoaeuei? oneeaaeiaiiy, ui iaoiiaeth? iaiao?aei?noue ?ic?iaee eiiieaena e?eoaaeueii-i?io?eaeoe/ieo caoiae?a aeey i?aeaeuaiiy eiiiainaoi?ieo iaoai?ci?a iaoa?einueei-ieiaeiaiai eiiieaeno o aeaii? eaoaai??? ae?iie. C oe??th iaoith i?iaaaeaii aea/aiiy ?ioiieia?/iiai noaoono nenoaie iaoe-ieiae-iiaiia?iaeaeaiee, a caaacia/aii? ii?iaeueii? ae?yeueiino? yei? aaaeeeao ?ieue a?ae?a?a? nenoaia ?ioi?oaoo, yea iaea?eueo /ooeeaa aei ae?? ?aae?aoe??. sse iieacaa aiae?c io?eiaiieo aeaieo, o aaa?oieo, ui iaoeathoue ia ?aae?aoe?eii caa?oaeiaieo oa?eoi??yo, niinoa??aa?oueny aeenaaeain eaiie nenoaie ?ioi?oaoo aaea ia ii/aoeo aaa?oiino? ? i?ia?aneaii ca?eueoo?oueny a ?? aeeiai?oe?, ui i?iyaey?oueny aee?eaeaiith a?aeiia?aeaeth ia aaa?oi?noue (oaae.1). A ianoaaeaieo a?oiao, ye a ?-e, oae ? a ??-e iieiaei? aaa?oiino?, niinoa??aaeinue cieaeaiiy e?eueeino? iniiaieo iiioeyoe?e e?ioioeeo?a: O-, A- e?ioioeeo?a ? NK- ee?oei, i?e/iio ??aaiue inoaii?o a ? iieiaei? aoa aeinoia??ii ieae/ee a ianoaaeaieo a?oiao ii??aiyii c eiio?ieai (7,23+1,4 % ? 9,34+1,7 % i?ioe 11,8+1,8 % a a?oi? ii??aiyiy, ?0,05). ??ai? O-e?ioioeeo?a a ? iieiaei? aaa?oiino? neeaaeaee a ae?oa?e cii? - 57,32+2,76 %, a o?ao?e - 58,4+3,6 % i?ioe 61,3+3,1 % a a?oi? ii??aiyiiy. ??aaiue A-e?ioioeeo?a noaiiaea a?aeiia?aeii 12,3+1,8 %, 14,9+1,7 % ? 15,8+2,3 % oa aoa aeinoia??ii ieae/ee a ae?oa?e iieiaei? aaa?oiino? o ae?iie, ye? i?iaeeaaee a ae?oa?e cii? caa?oaeiaiiy Cs 137 . I?e aiae?c? ai?noo noaiiioeyoe?e O-e?ioioeeo?a - O-oaeia??a ? O-noi?ani??a, ye? aaaaeathoueny aieiaieie ?aaoeyoi?aie ?ioiii? nenoaie, a ia?o?e iieiaei? aaa?oiino? a ianoaaeaieo a?oiao niinoa??aaeanue oaiaeaioe?y aei cieaeaiiy ye O-oaeia??a (40,72,61, 43,673,2 ? 44,92,89 %), oae ? O-noi?ani??a (31,542,03, 33,21,9 ? 36,181,08 %), i?e/iio inoaii? cieaeoaaeenue cia/ii a?eueoa, ui i?ecaiaeeei aei c?inoaiiy ?ioii?aaoeyoi?iiai ?iaeaena (O-oaeia?e/O-noi?ani?e). A ae?oa?e iieiaei? aaa?oiino? cieaeaiiy O-noi?ani??a a ianoaaeaieo a?oiao aoei aeinoia??ia ? i?ecaiaeeei aei c?inoaiiy ni?aa?aeiioaiiy O-oaeia?e/O-noi?ani?e (?0,05). Cieaeaiiy ooieoe?? O-noi?ani??a i?eaiaeeoue aei ia?aaaaeaiiy noeioethth/iai aieeao O-oaeia??a, a oiio /ene? ? ia A-ee?oeie, ye? i?iaeoeothoue aooiaioeo?ea. Ui noino?oueny iieaciee?a aoii?aeueiiai ?ioi?oaoo, oi a?aei?/aii cieaeaiiy ??ai?a iniiaieo eean?a ?ioiiaeiaoe?i?a (?0,05). Ciaioaiiy eiioeaio?aoe?? Ig G a e?ia? iaoa?? (9,25+0,4, 9,9+0,69 a/e i?ioe 12,06+0,81 a/e a a?oi? ii??aiyiiy, ?0,05) noi?iaiaeaeo?oueny cieaeaiiyi eiai ??aiy a ioiiaeii?e e?ia? (9,04+0,45, 10,2+0,22 a/e ? 11,1+0,4 a?aeiia?aeii, ?0,05), aea i?ia?aeiei ? ieaoeaioa?ia iaaeinoaoi?noue oa ?? iaoaaie?/ia iani?iiiaei?noue, yea iia??oo? oiiae ia?aoiaeo Ig G a?ae iaoa?? aei ieiaeo. Oea i?ecaiaeeoue aei i?eai?/aiiy ?ioi?oaoo o iiaiia?iaeaeaiiai oa iiaea iaoiiaeoe ii?ooaiiy i?ioean?a aaeaioaoe??. Ia 7-8 aeiao aeeooy Ig G i?iaeiaaeoaaa cieaeoaaaoenue ? neeaaeaa 8,7+0,26 a/e i?ioe 11,1+0,8 a/e (?0,05). Aeai? iaoeo aeine?aeaeaiue iieacaee, ui i?e iaeiie/aii? ?aae?iioee?ae?a a i?aai?ci? iaoa?? (2,9 ? a?eueoa Ae/ea) a?aeaoaa?oueny oo?iaia aioeaaiia noeioeyoe?y ?ioiii? nenoaie ieiaea. Oea i?aeoaa?aeaeo?oueny iayai?noth a ioiiaeii?e e?ia? Ig A oa a?eueo aenieei ??aiai a ii??aiyii? c a?oiith eiio?iey Ig M (?0,05). I?i oa, ui Ig A i Ig M ieiaeiaiai iioiaeaeaiiy na?ae/eoue ?o aeeiai?ea o iinoiaoaeueiiio ia??iae? - a?aenooi?noue cieaeaiiy ?o ??aiy a ia?o? 7 aei?a aeeooy, yea oa?aeoa?ii aeey iaoaaie?cio a?ee?a iaoa?einueeiai iioiaeaeaiiy. Ia ia?aae/aniee caione ?ioiii? nenoaie ieiaea aeaco? i?aeaeuaiee ??aaiue O-e?ioioeeo?a (56,87+1,2 %) o oaei? a?oie ae?oae, iayai?noue ?ioiieo eiiieaen?a oa ciaioaiiy e?eueeino? O-noi?ani??a (23,9+2,42 % ? 29,7+1,2 %, ?0,05). Oae? iniaeeaino? ieiaeiaiai ?ioiiiai noaoono ? oiiii aeey oi?ioaaiiy ci?iii? ?aaeoeaiino? o ae?oae, a iciaee aioeaaiii? noeioeyoe?? iiaeia a?aeianoe aei i?iaiinoe/ieo e?eoa???a ?icaeoeo o ae?oae aea?a?/ieo ?aaeoe?e. Iayai?noue o iiaiia?iaeaeaieo a 20,13 % aeiaaee?a (?? ciia – 26,56 ? 15,29 % - a ???-e cii?) aioeioeeaa?ieo aioeo?e, a oaeiae cieaeaiiy oei?/ii? aeoeaiino? ne?iaaoee e?ia? o 61,07 % iiaiia?iaeaeaieo i?ioe 6 % a a?oi? ii??aiyiiy (?0,05) na?ae/eoue i?i ii?ooaiiy ?ioiieia?/ii? oiea?aioiino? ? iiaea aooe iciaeith ?icaeoeo a iaeaooiueiio aooi?ioiieo caoai?thaaiue. Aecia/aia a?oia ?eceeo na?aae iiaiia?iaeaeaieo ii ?icaeoeo aooi?ioiii? iaoieia??, i?e/iio /enaeuei?noue oe??? a?oie i?iaeiaaeo? ca?eueooaaoenue. Ia iniia? io?eiaieo aeaieo ?ic?iaeaii ?ioiieia?/iee ianii?o iiaiia?iaeaeaiiai. Aeine?aeaeaiiy noaio eiiieaeniooai?aiiy aeicaieeei aeyaeoe iayai?noue ?ioiieo eiiieaen?a a ne?iaaooe? e?ia? o an?o ianoaaeaieo aaa?oieo. I?aeaeuaiiy ??aiy oee?eoethth/eo ?ioiieo eiiieaen?a a 2-3 ?ace (269,0+8,07 i?ioe 125,5+6,9 iae.iio.u?eueiino?, ?0,05) ca iaoeie aeaieie noi?iaiaeaeo?oueny ca?eueoaiiyi /anoioe oneeaaeiaiue aaa?oiino? oa iieia?a. I?ine?aeaeo?oueny /?oeee aca?iica'ycie i?ae iecueeei ??aiai Ig G, ye iane?aeie niiaeeaaiiy ?o aeey ?iaeoeaaoe?? aioeaai?a ieiaea, ye? iinooiathoue a e?iaioie iaoa??, ? aenieith u?euei?noth ?ioiieo eiiieaen?a, ye iane?aeie oeueiai niiaeeaaiiy. I?e aenieeo ??aiyo Oe?E (a?eueoa i?ae 125,0+6,9 iae.iio.u?e.), ye iieacaee iao? aeai?, ae?oe ia?iaeaeothoueny a noai? ao?en?? o 1,5 ?ace /ano?oa i?ae i?e iecueeeo ??aiyo. Aeyaeaia cai?ioiy caeaaei?noue i?ae ??aiai Ig G ? u?euei?noth ?ioiieo eiiieaen?a (r = - 0,49, ?0,05). Ia?aaaaeia a?eueo?noue aioeaai?a aoaeoeaii ae?i?io?oueny ee?oeiaie oaaioeeoa?ii? nenoaie i?ney aca?iiae?? c aioeo?eaie, oiaoi a i?ioean? ooai?aiiy Oe?E. A oie aea /an o 81,5 % aaa?oieo, ui iaoeathoue a Ia?iaeeoeueeiio ?aeii?, oa o 72,9 % a Ia?ooeueeiio aoee cia/ii ieae/eie iieacieee oaaioeeoa?ii? aeoeaiino? (?0,05). Oae? ae ci?ie aoei aeyaeaii aeey ?ioiai iieacieea oaaioeeoa?ii? aeoeaiino? - oaaioeeoa?iiai ?iaeaeno (?0,05). I?i iaai? ci?ie ?ioiieia?/ii? oiea?aioiino? i?aai?cio aaa?oieo a?oi ?aae?aoe?eiiai ?eceeo a a?e aeoeaaoe?? aooi?ioiieo i?ioean?a na?ae/eoue ? aeniea /anoioa aeieeiaiiy aioeoinoie?i?aeieo aioeo?e. Na?aae ianoaaeaieo ae?iie aioeoinoie?i?aeiee oaeoi? aeyaeaii o 47,69 % ae?iie a 2 cii?, 30,59 % - a 3 cii? i?ioe 6,0 % a a?oi? ii??aiyiiy (?0,05). Aeyaeaia i?yia ei?aeyoe?y i?ae ia?eiaoaeueiith iaoieia??th (oo?iaia cao?eiea ?icaeoeo ieiaea, eiai a?iien?y) oa iayai?noth aioeoinoie?i?aeieo aioeo?e (r=+0,69, ?0,05). Aooi?ioii? ii?ooaiiy a ?acoeueoao? iie?eeiiaeueii? aeoeaaoe?? A-e?ioioeeo?a, iayaiino? aioeo?e aei yaea?ieo eiiiiiaio?a ee?oeie /anoi anioe?ththoueny c aioeoinoie?i?aeieie aioeo?eaie o aeiaaeeao ia?aae/aniiai ia?a?eaaiiy aaa?oiino?, i?ciueiai aanoico, ieaoeaioa?ii? iaaeinoaoiino?, o?iiaioeeoiiai?? oa ?i. (A.I.Neaeaeueieeiaa e niaao., 1996; I.I.?iaeeianueea, 1997; E.Vogt et al., 1996). I?e aaa?oiino?, yea ?icaeaa?oueny ia oaeiio oii?, oe? ?iceaaee a ?ioii?e nenoai? iiaeooue caa??aaoenue, a iiaeooue iineethaaoenue ? i?eaiaeeoe aei i?eai?/aiiy /e iai?oaeaiiy ie?aieo eaiie caoenii? nenoaie i?aai?cio, ui iiaea aooe iaei??th c i?e/ei ?icaeoeo aeooa?nueeeo oneeaaeiaiue oa ?ioaeoe?eii? iaoieia??. Oea aecia/a? iaiao?aei?noue i?iaaaeaiiy ianiaoeeo?/ii? oa ?ioiiei?eaoth/i? oa?ai?? i?ioyaii aaa?oiino? ? a i?neyiieiaiaiio ia??iae?. Iaie ?ic?iaeaii eiiieaen e?eoaaeueii-i?io?eaeoe/ieo caoiae?a aeey aaa?oieo, ye? iino?eii iaoeathoue a ciiao ?aae?aoe?eiiai caa?oaeiaiiy, c o?aooaaiiyi c?ooaiue a nenoai? ?ioi?oaoo. A?i aeeth/a? i?iaeoeoe e?eoaaeueiiai oa?/oaaiiy (“Iie?nie”, “Aeaea?aea”); i?aia?aoe ?aae?ii?ioaeoi?ii? ae?? (iaeoeie, ii?nueea eaionoa, o?oi/a?, “Aioa?inaaeue”); ?ioiiiiaeoethth/o oa?ai?th (nieai?i, “?ioiae”, oeiie?i); aioeieneaeaioe (oieioa?iea aoeaoao, eaa?oeaoei); aeacaa?aaaioe (aoeaoeenae?oeeeiaa eeneioa, ae?i???aeaiie). I?e iayaiino? eiaaoeiiaoe/ieo oneeaaeiaiue oa i?e aenieeo oeo?ao aioeoinoie?i?aeieo aioeo?e i?ecia/aeenue aioeeiaaoeyioe (o?aeneia??i). Aea/aiiy aoaeoeaiino? eiiieaenii? oa?ai?? i?iaaaeaii o 100 aaa?oieo, ye? i?iaeeaathoue a oiiaao aeieia?/iiai caa?oaeiaiiy. A?oio ii??aiyiiy neeaee 50 ae?iie, ye? io?eioaaee o?aaeeoe?eio oa?ai?th (iin?aiee “Iniaeeaino? ia?aa?ao aaa?oiino?, ?iae?a, noaio iiaiia?iaeaeaieo o ae?iie, ye? caciaee ?aae?aoe?eiiai aieeao aiane?aeie *i?iiaeeuenueei? eaoano?ioe”, Ee?a, 1997). Ioe?ieo aoaeoeaiino? e?eoaaiiy i?iaiaeeee ia i?aenoaa? aiae?co ia?aa?ao aaa?oiino?, iieia?a oa iieaciee?a nenoaie ?ioi?oaoo iaoa?einueei-ieiaeiaiai eiiieaeno. I?iaaaeaiee aiae?c iieacaa aenieo aoaeoeai?nue canoinoaaiiy ?aeiiaiaeiaaiiai eiiieaena oa?ai??: 72 % ae?iie a?aei?oeee iie?auaiiy caaaeueiiai noaio, ii?iae?coaaany aiaoeo, caaaeueia i?aoeacaeaoi?noue (i?ioe 28 % a a?oi? ii??aiyiiy, ?0,05). I?ney i?iaaaeaiiai e?eoaaiiy niinoa??aaeenue iiceoeai? ci?ie a ?ioii?e nenoai? iaoa?einueei-ieiaeiaiai eiiieaeno. Cai?iiiiiaaia oa?ai?y ia? aea??eiao ?ioiiiiaeoethth/o ae?th ia caaaeueiee ioe O-e?ioioeeo?a, ia ?o noaiiioeyoe?? (O-oaeia??a ? O-noi?ani??a), ui a e?ioeaaiio ?acoeueoao? ii?iae?co? ooieoe?iioaaiiy aoaeoeaieo eaiie ?ioi?oaoo. Aeyaeyeanue oaiaeaioe?y aei ii?iae?caoe?? ??aiy O- ? A-e?ioioeeo?a, i?e/iio ??ai? A-e?ioioeeo?a aoee aeinoia??ii ieae/? o ae?iie Ia?iaeeoeueeiai ?aeiia (?0,05), i?ae aieeaii e?eoaaiiy ??aaiue ?o i?aeaeueany aei 13,81,84 % i?ioe 10,820,98 % a a?oi? ii??aiyiiy (?<0,05). Oaeo ae oaiaeaioe?th iaee ??ai? NK-ee?oei (aei 10,2+1,68 i?ioe 9,23+1,68), a oaeiae IgA (?0,05) . I?ae aieeaii e?eoaaiiy ??ai? IgG i IgM a iaio ianoaaeaieo a?oiao i?aeaeueeenue i?ae /an e?eoaaiiy ? aeinyaee ??ai?a eiio?ieueii? a?oie (?0,05). O ianoaaeaieo a?oiao niinoa??aaeinue i?aeaeuaiiy iieaciee?a ianiaoeeo?/ii? ?acenoaioiino? i?aai?cio. Oaaioeeoa?iee ?iaeaen i?aeaeueany o ae?iie Ia?iaeeoeueeiai ?aeiia aei 678,2425,12 i?ioe 526,8723,84 a a?oi? ii??aiyiiy (?0,05) ? aei 731,6527,12 i?ioe 618,823,48 o aaa?oieo Ia?o/nueeiai (?0,05). Aea yeui a 3 cii? caa?oaeiaiiy Cs 137 oeae iieaciee noaoenoe/ii ia a?ae??ciyany a?ae iieaciee?a a?oie ii??aiyiiy, oi a 2 cii? a?i caeeoaany aeinoia??ii ieae/ee i?ae a eiio?ieuei?e a?oi?, ? oea ia aeeaey/enue ia aeinoia??ia i?aeaeuaiiy eiai a ii??aiyii? c a?oiith, yea io?eioaaea o?aaeeoe?eia e?eoaaiiy. Oea na?ae/eoue i?i aeeaie? ii?ooaiiy ianiaoeeo?/ii? ?acenoaioiino? i?aai?cio aaa?oieo, ui iaoeathoue a ?? cii? caa?oaeiaiiy, ? ua ?ac i?aee?aneth? iaiao?aei?noue ?aoaeueiiai niinoa?aaeaiiy ? i?iaaaeaiiy o ieo e?eoaaeueii-i?io?eaeoe/ieo caoiae?a, c canoinoaaiiyi ?ioiiiiaeoethth/eo i?aia?ao?a. Ci?ie ??ai?a noaiiioeyoe?e O-e?ioioeeo?a (O-oaeia??a ? O-noi?ani??a) a?aeaoaaeinue a a?e ?o i?aeaeuaiiy, i?e/iio ia oii? iacia/iiai ca?eueoaiiy O-oaeia??a noaoenoe/ii aeinoia??ii ca?eueooaaany ??aaiue O-noi?ani??a, ui i?ecaiaeeoue aei ii?iae?caoe?? ni?aa?aeiioaiiy O-oaeia?e/O-noi?ani?e a ianoaaeaieo a?oiao. Oae, ??aaiue O-oaeia??a o ae?iie Ia?iaeeoeueeiai ?aeiio ca?eueoeany c 39,62,52 aei 43,242,54 %, O-noi?ani??a c 30,12,89 aei 41,451,35 % (?0,05), a Ia?ooeueeiio ?aeii? - O-oaeia??a c 39,781,64 aei 41,391,89 % ? O-noi?ani??a c 32,462,78 aei 38,741,34 % (?0,05). Oea ia? aaeeea cia/aiiy, ine?eueee a iao /an aaaaea?oueny, ui ci?ie aaeaino O-oaeia??a ? O-noi?ani??a a a?e noi?an?? ? aaaeeeaei iaoai?ciii ?ioiieia?/iiai caaacia/aiiy aaa?oiino?. I?ae aieeaii eiiieaenii? oa?ai?? cia/ii cieceeenue ??ai? Oe?E (?0,05), a?aei?/aeiny ciaioaiiy iaeaea a 1,5 ?ace oeo??a aioeoinoie?i?aeieo aioeo?e ? aioeo?e aei niaaeeiaiai iaoa??aeo ee?oeie ye a e?ia? iaoa??, oae ? a noaeeiao ioiiaeie. Iiceoeaii aieeaa? ?aeiiaiaeiaaia iaie oa?ai?y ia ia?aa?a aaa?oiino?, iieia?a, noai ieiaea ? iiaiia?iaeaeaiiai. *anoioa oneeaaeiaiue o oaeeo aaa?oieo iii?oii ieae/a, i?ae o ae?iie, ye? io?eioaaee o?eueee o?aaeeoe?eia e?eoaaiiy (?0,05). I?e oeueiio caa?ica ia?a?eaaiiy aaa?oiino? a?aei?/aia o 12,0 % ae?iie i?ioe 26,0 % a a?oi? ii??aiyiiy (?0,05). *anoioa i?ci?o aanoic?a ? a?iien?y ieiaea ciaioeeanue a?eueo i?ae o 2 ?ace, neaae?noue ?iaeiai? ae?yeueiino? ? e?iaioa/? a 1,5 ?ace (?0,05). Ciaioeeanue /anoioa aiai?? aaa?oieo ia 15,0 %, ano?en?e iiaiia?iaeaeaieo ia 12,0 %. Ia?aa?a ia??iaeo ?aiiuei? iaiiaoaeueii? aaeaioaoe?? o iiaiia?iaeaeaieo, iaoa?? yeeo io?eioaaee eiiieaenio oa?ai?th, aoa cia/ii e?auei. Caoai?thaai?noue iiaiia?iaeaeaieo neeaea 16,0 % i?e 36,0 % o ae?oae a?oie ii??aiyiiy. Oaeei /eiii, ?acoeueoaoe aeine?aeaeaiue i?aeoaa?aeeee aenieo aoaeoeai?noue ?aeiiaiaeiaaii? oa?ai??, yea ni?ey? cieaeaiith /anoioe ?icaeoeo aeooa?nueei? ? ia?eiaoaeueii? iaoieia??, ui a cia/i?e i??? iaoiiaeaii ii?iae?caoe??th iieaciee?a nenoaie ?ioiiaaiaco. Oaea aoaeoeai?noue oa?ai?? aeicaiey? ?aeiiaiaeoaaoe ?? aeey ai?iaaaeaeaiiy a i?aeoeeo. AENIIAEE 1. O ae?iie a?oie ?aae?aoe?eiiai ?eceeo aaa?oi?noue ? iieiae noi?iaiaeaeothoueny cia/iith /anoioith oneeaaeiaiue (i?ci? aanoice, caa?ica ia?a?eaaiiy aaa?oiino?, aiai??, cao?eiea ?icaeoeo ieiaea, a?iien?y, ianai?/ania a?aeoiaeaeaiiy iaaeieiieiaeieo aiae, aiiiae?? iieiaiai? ae?yeueiino?, e?iaioa/?, ano?en?y iiaiia?iaeaeaiiai). Iaea?eueoa /anoioa oneeaaeiaiue niinoa??aa?oueny o ae?iie, ye? i?iaeeaathoue a ae?oa?e cii? caa?oaeiaiiy Cs 137. Oe? iieacieee ei?aethaaee c ??aiai caa?oaeiaiiy i?noey i?iaeeaaiiy oa ia caaaeaee ei?aethaaee c aeicith ii?ii?iaiiy. 2. O ae?iie, ye? i?iaeeaathoue a oiiaao ae?? iaeeo aeic ?aae?aoe??, ia? i?noea i?eai?/aiiy ??cieo eaiie ee?oeiiiai ? aoii?aeueiiai ?ioi?oaoo, ianiaoeeo?/ieo oaeoi??a caoenoo, /anoioa ? oa?aeoa? yeiai iaoiiaeai? ia?aa?aii aaa?oiino? ? ?? oa?i?iii. Aeenaaeain o ni?aa?aeiioaii? O-oaeia??a oa O-noi?ani??a a noi?iio cieaeaiiy inoaii?o, ciaioaiiy e?eueeino? O- e?ioioeeo?a ? ?ioiiaeiaoe?i?a G, M, i?aeaeuaiiy Oe?E, cieaeaiiy aeoeaiino? ianiaoeeo?/ieo oaeoi??a caoenoo oa aenie? oeo?e aioeoinoie?i?aeieo aioeo?e, na?ae/eoue i?i aeaci?aai?caoe?th o?c?ieia?/ii? ?ioiii? a?aeiia?ae? oa i?aeaeuaiiy aooinainea?e?caoe?? i?aai?cio aaa?oii?. 3. Iiaiia?iaeaeai? iaoa??a a?oie ?aae?aoe?eiiai ?eceeo iathoue ii?ooaiiy ?ioiieia?/iiai aiiainoaco, ye? coiiaeththoue noeeuei?noue aei ?icaeoeo aoi?eiieo ?ioiiaeao?oeeoieo noai?a oa oi?ioaaiiy aooi?ioiii? iaoieia??. 4. I?i iaai? ci?ie ?ioiieia?/ii? oiea?aioiino? iiaiia?iaeaeaieo a?oi ?eceeo ii ?icaeoeo aooi?ioiii? iaoieia?? na?ae/eoue iayai?noue a ioiiaeii?e e?ia? Oe?E, Ig A oa a?eueo aenieee ??aaiue Ig M, ciaioaiiy O-noi?ani??a, iayai?noue aioeo?e aei niaaeeiaiai iaoa??aeo ee?oeie, cieaeaiiy oei?/ii? aeoeaiino? ne?iaaoee. 5. Iayai?noue a ioiiaeii?e e?ia? IgA oa a?eueo aenieee ??aaiue a ii??aiyii? c a?oiith eiio?iey IgM ia ? iieacieeii ?ioaeoe?eiiai i?ioeano, a a?aeia?aaea? oo?iaio aioeaaiio noeioeyoe?th ?ioiii? nenoaie ieiaea. Cieaeaiiy eiioeaio?aoe?? IgG ii?yae c a?aeoeeaiiyi o noai? aaeaioaoe?? na?ae/eoue i?i iecueeee ??aaiue ianeaiiai ?ioi?oaoo o aeaii? eaoaai??? iiaiia?iaeaeaieo oa ca?eueoo? ?ecee aaeoa??aeueii-a??onieo oneeaaeiaiue a iaiiaoaeueiiio ia??iae?. 6. Nooo?aa ii?ooaiiy iieaciee?a O- ? A-e?ioioeeo?a, ni?aa?aeiioaiiy O-?aaoeyoi?ieo ee?oei, i?eai?/aiiy aoii?aeueiiai ?ioi?oaoo, cieaeaiiy oaaioeeoa?ii? aeoeaiino? iaeo?io?e?a, aenieee oeo? aioeoinoie?i?aeieo aioeo?e o aaa?oieo a?oie ?aae?aoe?eiiai ?eceeo ? iaei??th c i?e/ei ?icaeoeo aeooa?nueeeo ? ia?eiaoaeueieo oneeaaeiaiue oa ? iniiaith iaoiaaiaoe/iiai iaa?oiooaaiiy aeey i?ecia/aiiy ?ioiiei?eaoth/eo i?aia?ao?a. 7. Aaeineiiaeaiee eiiieaen e?eoaaeueii-i?io?eaeoe/ieo caoiae?a c canoinoaaiiyi i?iaeoeo?a e?eoaaeueiiai oa?/oaaiiy, aioeieneaeaio?a, ?ioiiiiaeoethth/eo i?aia?ao?a, aeacaa?aaaio?a, ?aae?ii?ioaeoi??a, a i?e aioeoinoie?i?aeiiio neiae?ii? - aioeeiaaoeyio?a, ni?ey? ii?iae?caoe?? iieaciee?a ?ioi?oaoo, iie?auaiith caaaeueiiai noaio aaa?oieo ?aa?iia aaa??? ia *AAN, ciaioaiith /anoioe aeooa?nueeeo ? ia?eiaoaeueieo oneeaaeiaiue, ui aeicaiey? ?aeiiaiaeoaaoe eiai aeey oe?ieiai ai?iaaaeaeaiiy a i?aeoeeo. I?AEOE*I? ?AEIIAIAeAOe?? 1. A a?oio ?eceeo ii ?icaeoeo aeooa?nueeeo ? ia?eiaoaeueieo oneeaaeiaiue ne?ae a?aeiineoe aaa?oieo, ye? iino?eii ciaoiaeyoueny a oiiaao ae?? iaeeo aeic ?aae?aoe??. A eiiieaen ianoaaeaiue oaeeo aaa?oieo oa ?o iiaiia?iaeaeaieo iaiao?aeii aeeth/aoe aea/aiiy iieaciee?a nenoaie ?ioi?oaoo c o?aooaaiiyi ?aae?iiao??? iaoa?einueei-ieiaeiaiai eiiieaeno (EAE) ? ??aiy caa?oaeiaiiy Cs i?noey i?iaeeaaiiy. 2. Aeey i?iaiicoaaiiy ?icaeoeo aooi?ioiii? iaoieia?? o ae?oae a iaeaooiueiio ?aeiiaiaeothoueny ianooii? eiie?aoi? oaeoi?e ?eceeo: o iaoa??: - aenie? oeo?e aioeoinoie?i?aeieo aioeo?e a e?ia? (a?eueoa 23 eie?a?aoe?iiieo iaeeieoeue a 1 ie); - aenie? ??ai? oee?eoethth/eo ?ioiieo eiiieaen?a (aeua 150 iae. iio. u?eueiino?) o iiaiia?iaeaeaieo: - ciaioaiiy e?eueeino? O-noi?ani??a (aei 23%); - iiyaa a ioiiaeii?e e?ia? Ig A oa a?eueo aenieee ??aaiue Ig M (0,19 a/e); - iiyaa oee?eoethth/eo ?ioiieo eiiieaen?a (aeua 120 iae. iio. u?eueiino?); - iayai?noue aioeo?e aei niaaeeiaiai iaoa??aeo ee?oeie; - cieaeaiiy oei?/ii? aeoeaiino? ne?iaaoee e?ia? (ieae/a 1/32). 3. C iaoith i?io?eaeoeee ? ei?aeoe?? ii?ooaiue nenoaie ?ioi?oaoo o aaa?oieo ?aa?iia aaa??? ia *AAN ?aeiiaiaeo?oueny e?eoaaeueii-i?io?eaeoe/iee eiiieaen, ui aeeth/a? i?iaeoeoe e?eoaaeueiiai oa?/oaaiiy, aioeieneaeaioe, aeacaa?aaaioe, ?ioiiei?eaoth/? i?aia?aoe, aeaei?ii?aioe c ?aae?iiao?e/iei eiio?ieai aei ? i?ney e?eoaaiiy. I?e iayaiino? eiaaoeiiaoe/ieo oneeaaeiaiue oa i?e aenieeo oeo?ao aioeoinoie?i?aeieo aioeo?e i?ecia/athoueny aioeeiaaoeyioe. NIENIE I?AOeUe, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. Iniaeeaino? ?ioiieia?/iiai noaoono o aaa?oieo a?oie ?aae?aoe?eiiai ?eceeo // Iaae?ao??y, aeooa?noai ? a?iaeieia?y. - 1997. - N 6. - N. 71 - 72. 2. Aieea iaeeo aeic ?ii?coth/iai aei?ii?ithaaiiy ia nenoaio iaoe-ieaoeaio-ie?ae (iaeyae e?oa?aoo?e) // Iaae?ao??y, aeooa?noai ? a?iaeieia?y. - 1997. - N 6. - N. 89 - 92 (Aeaoeaae/ A.?., Iaa?ioeueea A.A., ssithoa N.I., Eieii?e/aiei O.A., Aeaaeaeiaa TH.A.). 3. Alterations of immune system of pregnant women and new-borne from radioactive contaminated areas // Acta Obstetricia et Gynecologica Scandinavica. - 1997. - V.76, N 167. - P.103. 4. Ae?aaiinoeea ? i?io?eaeoeea iaaeiiooaaiiy o aaa?oieo, ye? iaoeathoue ia eiio?ieueiaaieo ii ?aae?aoe?? oa?eoi??yo // Ca??iee iaoeiaeo i?aoeue “Iaaeiiooaaiiy aaa?oiino?.” - Ee?a, 1997. - N. 295-297 (Iie?ee A.I., ssithoa N.I., Aeaaeaeiaa TH.A.). 5. Iniaaiiinoe eiioiiie nenoaiu o aa?aiaiiuo e eo iiai?iaeaeaiiuo, i?iaeeaathueo a ciia ?aaeeiaeoeaiiai caa?yciaiey // Iaoa?eaeu iao/ii-i?aeoe/aneie eiioa?aioeee “*a?iiaueue e caei?iauea ianaeaiey”. - *anoue 2. - Eeaa, 1994. - N. 154-156 (Iie?ee A.A., Iaaeaaaeue A.E., *a?iuoia A.I., Ieeoeeia E.E., ?aaeuo O.A.). 6. Ae?aaiinoeea noaio ieiaea o aaa?oieo, ye? iaoeathoue ia eiio?ieueiaaieo oa?eoi??yo // Oace aeiiia?aeae iaoeiai-i?aeoe/ii? eiioa?aioe?? aeooa??a-a?iaeieia?a Oe?a?ie “Ooieoe?iiaeuei? iaoiaee aeine?aeaeaiiy a aeooa?noa? oa a?iaeieia??”. - Aeiiaoeuee, 1994. - N. 232 (ssithoa N.I., Iie?ee A.A., Aeaaeaeiaa TH.A.). 7. Disturbances of immune system of pregnant women from radioactive contaminated areas // International symposium "Immunology of reproduction". - Kiev (Ukraine). - 1996. - P. 59. 8. Aeaye? aniaeoe ?ioiieia?/ieo ci?i a iaoa?einueei-ieiaeiaiio eiiieaen? o aaa?oieo, ui i?iaeeaathoue ia oa?eoi??yo, iino?aaeaeaaoeo aiane?aeie aaa??? ia *AAN // Oace aeiiia?aeae eiioa?aioe?? iieiaeeo a/aieo “Aeooaeuei? ieoaiiy aeooa?noaa oa a?iaeieia??”. - A?iieoey, 1995. - N. 168-169. 9. Ae?aaiinoeea a?iien?? ieiaea o ae?iie, ui iaoeathoue ia eiio?ieueiaaieo oa?eoi??yo // Oace aeiiia?aeae eiioa?aioe?? iieiaeeo a/aieo “Aeooaeuei? ieoaiiy aeooa?noaa oa a?iaeieia??”. - A?iieoey, 1995. - N. 50-51 (Aeaaeaeiaa TH.A., ssithoa N.I.). 10. Features of current of pregnancy and deliveries at the women of region of Chernobyl disaster // Book of abstracts “13th congress of the European association of gynecologists and obstetricians (EAGO)”. - Jerusalem (Israel). - 1998. - P. 97. AIIOAOe?ss Na?a??iei N.A. Iniaeeaino? ?ioiieia?/iiai noaoono nenoaie iaoe-ieiae-iiaiia?iaeaeaiee o aaa?oieo a oiiaao ae?? iaeeo aeic ?aae?aoe??. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.01 - aeooa?noai ? a?iaeieia?y. - ?inoeooo iaae?ao???, aeooa?noaa ? a?iaeieia?? AII Oe?a?ie, Ee?a, 1998. ?iaioa i?enay/aia ieoaiiyi i?io?eaeoeee oa oa?ai?? aeooa?nueeeo ? ia?eiaoaeueieo oneeaaeiaiue o aaa?oieo, ui iaoeathoue a oiiaao iino?eiiai aieeao iaeeo aeic ?ii?coth/iai ii?ii?iaiiy. Anoaiiaeaii caeaaei?noue i?ae /anoioith oneeaaeiaiue aaa?oiino? ? iieia?a oa u?euei?noth caa?oaeiaiiy Cs ciie i?iaeeaaiiy. Aecia/aii iniaeeaino? ?ioiieia?/iiai noaoono nenoaie iaoe-ieiae-iiaiia?iaeaeaiee, ia iniia? yeeo aeae?eaia a?oia ?eceeo ii ?icaeoeo aooi?ioiii? iaoieia?? na?aae ae?oae. ?ic?iaeaii ?ioiieia?/iee ianii?o iiaiia?iaeaeaiiai. Cai?iiiiiaaii iaoiae i?io?eaeoeee ? oa?ai??, ni?yiiaaiee ia ei?aeoe?th aeyaeaieo ii?ooaiue, yeee aeicaiey? cieceoe /anoioo oneeaaeiaiue c aieo iaoa?? ? ieiaea, iieacaia eiai aoaeoeai?noue. Eeth/ia? neiaa: aaa?oi?noue, iieiae, ieiae, iiaiia?iaeaeaiee, ?ioi?oao, ?ii?coth/a ii?ii?iaiiy. AIIIOAOeEss Na?aeaiei N.A. Iniaaiiinoe eiioiieiae/aneiai noaoona nenoaiu iaoue-ieiae-iiai?iaeaeaiiue o aa?aiaiiuo a oneiaeyo aeaenoaey iaeuo aeic ?aaeeaoeee. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.01 - aeooa?noai e aeiaeieiaey. - Einoeooo iaaeeao?ee, aeooa?noaa e aeiaeieiaee AII Oe?aeiu, Eeaa, 1998. ?aaioa iinayuaia aii?inai i?ioeeaeoeee e oa?aiee aeooa?neeo e ia?eiaoaeueiuo ineiaeiaiee o aa?aiaiiuo, i?iaeeaathueo a oneiaeyo iinoiyiiiai aicaeaenoaey iaeuo aeic eiiece?othuaai eceo/aiey. Onoaiiaeaia caaeneiinoue iaaeaeo /anoioie ineiaeiaiee aa?aiaiiinoe, ?iaeia e ieioiinoueth caa?yciaiey Cs ciiu i?iaeeaaiey. Auyaeaiu iniaaiiinoe eiioiieiae/aneiai noaoona nenoaiu iaoue-ieiae-iiai?iaeaeaiiue, ia iniiaa eioi?uo auaeaeaia a?oiia ?enea ii ?acaeoeth aooieiioiiie iaoieiaee n?aaee aeaoae. ?ac?aaioai eiioiieiae/aneee ianii?o iiai?iaeaeaiiiai. I?aaeeiaeai eiiieaen i?ioeeaeoeee e oa?aiee, iai?aaeaiiue ia ei??aeoeeth auyaeaiiuo ia?ooaiee, iicaieythuee nieceoue /anoioo ineiaeiaiee ni noi?iiu iaoa?e e ieiaea, iieacaia aai yooaeoeaiinoue. Eeth/aaua neiaa: aa?aiaiiinoue, ?iaeu, ieiae, iiai?iaeaeaiiue, eiioieoao, eiiece?othuaa iaeo/aiea. ANNOTATION Sergiyenko S.V. Peculiarites of the immunological status of system mother-foetus-newborn in pregnant women in conditions of action of small dozes of radiation. - Manuscript. Thesis for scientific degree of candidate of medical sciences by speciality 14.01.01 - obstetric and gynaecology. - Institute paediatric, obstetric and gynaecology, Acadamy of Medical Sciences of Ukraine, Kiev, 1998. The study is devoted to problem of preventive maintenance and therapy of obstetric and perinatal complications in the pregnant woman living in conditions of constant influence of small dozes of ionising radiation. The dependence between frequancy of pregnancy and delivery complications and density of Cs pollution of a of residing zone is established. The features of the immunological status of mother-foetus-newborn system are revealed, on the basis of which the group of risk on development of a autoimmune pathology among children is allocated. Immunological passport of newborn is work out. The complex of preventive maintenance and therapies directed on correction of revealed infringements, allowing to lower frequency of complications is offered. Its efficiency is shown. Key words: pregnancy, foetus, new-born, immunity, ionising irradiation.

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