2

AEAAeAI?ss IAAeE*IEO IAOE OE?A?IE

?INOEOOO EA?Ae?IEIA??

?i. aeaae. I.Ae. NO?AAEANEA

?ooeaiei Na?a?e Ieeieaeiae/

OAeE: 616.127-005.8+616.127-005.4]:612.172

AAIIAeEIAI?*I? AeAOA?I?IAIOE AEAEO?E*II?

IANOAA?EUeIINO? NA?Oess O OAI?EO IA ?ON, ssE?

IA?AIANEE ?IOA?EO I?IEA?AeA

14.01.11. — Ea?ae?ieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a-1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a ?inoeooo? ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea AII
Oe?a?ie.

Iaoeiaee ea??aiee:

aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee Ia?oiiaiei
Ieaenaiae? Ieeieaeiae/ caa?aeoaa/ a?aeae?eaiiy ?aai?iaoe?? oa
?ioaineaii? oa?ai?? ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea
AII Oe?a?ie.

Io?oe?ei? iiiiaioe:

aeaaeai?e IAI Oe?a?ie, aeieoi? iaaee/ieo iaoe, i?ioani? Iieaaiei Ieaen?e
Ieaen?eiae/, caa?aeoaa/ a?aeae?eii aenia?aiaioaeueii? ea?ae?ieia??
?inoeoooo o?c?ieia?? ?i. I.I. Aiaiiieueoey IAI Oe?a?ie;

aeieoi? iaaee/ieo iaoe, i?ioani? N??aiei TH??e Ieeieaeiae/ caa?aeoaa/
a?aeae?eaiiy neiioiiaoe/ii? a?ia?oaic?? c eaai?aoi???th
aeno?aei?ii?aeueieo iaoiae?a e?eoaaiiy ?inoeoooo ea?ae?ieia?? ?i. aeaae.
I.Ae. No?aaeanea AII Oe?a?ie.

I?ia?aeia onoaiiaa:

Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y IIC Oe?a?ie, eaoaae?a
oa?ai?? ? 2.

Caoeno aeena?oaoe?? a?aeaoaeaoueny » 18 » o?aaiy 1999 ?. i 10 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.616.01 i?e ?inoeooo?
ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea AII Oe?a?ie, (252151 i. Ee?a,
aoe. Ia?iaeiiai iiie/aiiy, 5).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeoooo
ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea AII Oe?a?ie, (252151 i.Ee?a,
aoe. Ia?iaeiiai iiie/aiiy 5).

Aaoi?aoa?ao ?ic?neaiee » 17 » ea?oiy 1999 p.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Aeaye N.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. Aino?ee iioa?eo iiiea?aea aei oaia?ioiueiai /ano
i?iaeiaaeo? caeiaoe iaeia c ia?oeo iinoeue o no?oeoo?i nia?oiinoi
ianaeaiiy i?iieneiai ?icaeiaieo e?a?i. Oea aecia/a? i?ii?eoaoiinoue
iaoeiaeo aeine?aeaeaiue, ni?yiiaaieo ye ia oaeineiiaeaiiy oaeoeee
aaaeaiiy oai?eo a aino?iio ia?iiaei iioa?eoo iiiea?aea, oae i ia
ai?ioueao c aiaeaeaeaieie ianeiaeeaie oeueiai caoai?thaaiiyth —
na?oeaaith iaaeinoaoi?noth oa oeoii/eiaeie ii?ooaiiyie ?eoio na?oey, ui
caa?iaeothoue aeeooth (I.A. Iaco? 1983, 1985, Estes N. et al. 1986, Kim
H. et al. 1991). Ia aeeaey/enue ia cia/i? oni?oe a e?eoaaii? aino?iai
ia??iaeo ?ioa?eoo i?iea?aea ia oieoaeueiiio aoai?, a ie?aieo a?oiao
oai?eo eoioeyoeaia nia?oi?noue ia?aaeuo? 10% ca ia?oee ??e i?ney
aeieeiaiiy caoai?thaaiiy, i?e/iio a?eueoa /anoea oe??? nia?oiino?
aeiaiaeeoueny ia ?aioiao nia?oue aiane?aeie oeoii/eiaeo oao?a?eoi?e
(Andresen D. et al. 1990, Amsterdam E. et al. 1990).

Aeey aeine?aeaeaiiy iaoai?ci?a ?icaeoeo oeoii/eiaeo ii?ooaiue ?eoio
na?oey a ee?i?/i?e i?aeoeoe? c 1972 ?. canoiniaothoue ?iaaceaia
aeaeo?io?c?ieia?/ia aeine?aeaeaiiy na?oey, ui aeeth/a? i?ia?aiiaaio
aiaeiea?ae?aeueio noeioeyoe?th oeoii/e?a na?oey (Brugada J., Brugada P.
et al. 1972, 1984, 1989, Hessen S. et al. 1990). Ia oaia??oi?e /an oeae
iaoiae aaaaea?oueny iaea?eueo ?ioi?iaoeaiei o ieai? aeyaeaiiy
aeaeo?e/ii? ianoaa?eueiino? i?iea?aea oa ii?oieia?/iiai a?eoiiaaiiiai
noano?aoo ? canoiniao?oueny o ??cieo eaoaai??e oai?eo, a oiio /ene? o
oai?eo ia ?oai?/io oai?iao na?oey, ye? ia?aianee ?ioa?eo i?iea?aea. Ca
inoaii? ?iee aeaiee iaoiae ana oe?oa canoiniao?oueny aeey aeae?eaiiy
oai?eo c aenieei ?eceeii, i?aeai?o aaeaeaaoii? oa?ai?? oa eiio?ieth ??
aoaeoeaiino? (A.A. Aia?ia oa ni?aaao. 1993, 1995, TH.E. Eaee oa ni?aaao.
1989, 1991, Bourk J et al. 1991, Carbucicchio C. 1998).

?acii c oeei, o no/ani?e e?oa?aoo?? iaia? aeaieo a?aeiinii caeaaeiino?
aeae?a ?iaeoeiaaieo i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe??
oeoii/eiaeo oao?ea?ae?e o oai?eo, ye? ia?aianee ?ioa?eo i?iea?aea, a?ae
ia?aiao??a aioo??oiueina?oeaai? aaiiaeeiai?ee oa ae?aaeaiino? ee?i?/ieo
i?iya?a na?oeaai? iaaeinoaoiino?. Iaeiae a?aeiii, ui ianinia ooieoe?y
na?oey ia? i?yiee aieea ia oieoaeueio oa i?neyoieoaeueio eaoaeuei?noue
oai?eo, ye? ia?aianee aino?ee ?ioa?eo i?iea?aea (Luisada A. et al. 1985,
Bigger J. et al. 1987, Tseffer M., Braunwald E. 1990).

Oaeei /eiii, aeeiiaiiy iaoeiaiai aeine?aeaeaiiy, a yeiio aoei a
i?iaaaeaii ni?anoaaeaiiy iieaciee?a aioo??oiueina?oeaai?? aaiiaeeiai?ee,
aecia/aieo iaoiaeii aeaii??ii? aoiea?ae?ia?ao??, c aeaieie i?ia?aiiaaii?
noeioeyoe?? oeoii/e?a na?oey, i?iaaaeaii? o oai?eo a ??ci? oa?i?ie i?ney
ia?aianaiiai aino?iai ?ioa?eoo i?iea?aea, ? aeooaeueiei oa ia? iaoeiaa ?
i?aeoe/ia cia/aiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa “Aaiiaeeiai?/i? aeaoa?i?iaioe aeaeo?e/ii? ianoaa?eueiino? na?oey
o oai?eo ?ON, ye? ia?aianee ?ioa?eo i?iea?aea” aeeiiaia a ?aieao oaie
“I?iaiicoaaiiy ia?aa?ao ia?ieneciaeueieo ii?ooaiue na?oeaaiai ?eoio,
iiaoi?ieo aino?eo ii?ooaiue ei?iia?iiai e?iaiia?ao ? ?ic?iaea caoiae?a
ii ?o i?io?eaeoeoe? c iaoith caiia?aaiiy ?aioiai? na?oeaai? nia?o?.”

Iaoa ? caaea/? aeine?aeaeaiiy. Aea/eoe aca?iica’ycie iieaciee?a
aioo??oiueina?oeaai? aaiiaeeiai?ee oa ?iaeoeiaaiino? oeoii/eiaeo
oao?ea?ae?e o oai?eo ia ?ON o i?aeaino?iio ia??iae? ?ioa?eoo i?iea?aea
ia 2–3-io oeaei? caoai?thaaiiy oa o oai?eo ia i?ney?ioa?eoiee
ea?ae?ineea?ic (o oa?i?ie a?eueoa 6 i?nyoe?a i?ney ia?aianaiiai aino?iai
?ioa?eoo i?iea?aea) aeey ioe?iee ?eceeo ?icaeoeo caa?iceeaeo aeey aeeooy
a?eoi?e oa ?aioiai? nia?o?. Aeey aeinyaiaiiy iaoe aoee iinoaaeaie
ianooii? caaea/?:

1. Aea/eoe oa ni?anoaaeoe /anoioo oa aeaee ?iaeoeiaaieo i?e
i?ia?aiiaai?e noeioeyoe?? oeoii/e?a na?oey oeoii/eiaeo oao?a?eoi?e a
??ci? oa?i?ie i?ney ia?aianaiiai aino?iai ?ioa?eoo i?iea?aea.

2. Aeine?aeeoe aca?iica’ycie aeae?a ?iaeoeiaaieo oeoii/eiaeo
oao?ea?ae?e oa noaio aioo??oiueina?oeaai? aaiiaeeiai?ee a ??ci? oa?i?ie
i?ney ia?aianaiiai aino?iai eioa?eoo i?iea?aea.

3. Aecia/eoe caeaaei?noue i?ae aaiiaeeiai?/ieie ia?aiao?aie na?oey oa
o?aceea?noth i?iea?aea aei niiioaieo oa ?iaeoeiaaieo i?ae /an
aeaeo?io?c?ieia?/ieo aeine?aeaeaiue na?oey oeoii/eiaeo oao?ea?ae?e.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. A ?acoeueoao? i?iaaaeaiiai
aeine?aeaeaiiy io?eiai? iia? iaoeia? aeai? uiaei aieeao iieaciee?a
aioo??oiueina?oeaai? aaiiaeeiai?ee oa aaiiao??? ii?iaeieie e?aiai
oeoii/ea ia oi?ioaaiiy oaiiiaio aeaeo?e/ii? ianoaa?eueiino? i?iea?aea ca
aeaieie i?ia?aiiaaii? noeioeyoe?? oeoii/e?a o oai?eo ia ?ON a ??ci?
oa?i?ie i?ney ia?aianaiiai ?ioa?eoo i?iea?aea.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. A?aoiaoth/e ?acoeueoaoe
aeeiiaii? ?iaioe, i?iaaaeaiiy ?iaaceaiiai aeaeo?io?c?ieia?/iiai
aeine?aeaeaiiy na?oey c iaoith aeyaeaiiy aeaeo?e/ii? ianoaa?eueiino?
i?iea?aea (a?eoiiaaiiiai noano?aoo) ?aeiiaiaeiaaii oai?ei ia aino?ee
?ioa?eo i?iea?aea c aiaa?eciaie na?oey, ai?ciaeaie coieiee e?iaiia?ao a
aiaiiac?, o?eaaeith e?aioeoii/eiaith iaaeinoaoi?noth oa c aeeeyoaoe??th
ii?iaeieie e?aiai oeoii/ea. Iieacaia iaaeioe?euei?noue i?iaaaeaiiy c
oe??th iaoith i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey o oai?eo
aino?ei ?ioa?eoii i?iea?aea oa iino?ioa?eoiei ea?ae?ineea?icii ?c
ca?a?no?iaaieie niiioaiieie iaiaaeaie no?eei? oeoii/eiai? oao?ea?ae??.

?aeiiaiaeiaai? ??ci? i?aeoiaee i?e e?eoaaii? iiiiii?oieo oa iie?ii?oieo
oeoii/eiaeo oao?ea?ae?e o oai?eo ia aino?ee ?ioa?eo i?iea?aea (ia 2–3
oeaei? caoai?thaaiiy) oa ia iino?ioa?eoiee ea?ae?ineea?ic.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy a i?aeoeeo. Aeai?, io?eiai?
i?e aeeiiaii? ?iaioe, aeei?enoai? a iaaeaaeia?/iiio i?ioean? ia eaoaae??
ea?ae?ieia?? oa ooieoe?iiaeueii? ae?aaiinoeee Ee?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E. Ooi?ea IIC Oe?a?ie, eaoaae?ao
oa?ai?? oa ii?iaeueii? o?c?ieia?? iaaee/iiai ?inoeoooo Oe?a?inueei?
anioe?aoe?? ia?iaeii? iaaeeoeeie, ui i?aeoaa?aeaeaii aeoaie
ai?iaaaeaeaiiy. ?acoeueoaoe aeine?aeaeaiiy aoee ai?iaaaeaeai? a i?aeoeeo
?iaioe a?aeae?eaiiy ?aai?iaoe?? oa ?ioaineaii? oa?ai?? ?inoeoooo
ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea AII Oe?a?ie a oaeiae i?e
?ic?iaoe? iaoiaee/ieo ?aeiiaiaeaoe?e ii e?eoaaiith oai?eo ia ?ON c
ii?ooaiiyi na?oeaaiai ?eoio.

Iniaenoee aianie caeiaoaa/a. I?ae /an aeeiiaiiy aeena?oaoe?eii? ?iaioe
caeiaoaa/ ia iaoeiaee nooi?iue eaiaeeaeaoa iaaee/ieo iaoe ?ooeaiei N.I.
iniaenoi i?eeiaa o/anoue o i?iaaaeaii? ?iaaceaieo aeaeo?io?c?ieia?/ieo
aeine?aeaeaiue o oai?eo ia aino?ee ?ioa?eo i?iea?aea oa iino?ioa?eoiee
ea?ae?ineea?ic, ye? oa?eoee o ianoaaeaiiy, naiino?eii i?ia?a aiae?c oa
noaoenoe/io ia?iaeo io?eiaieo ?acoeueoao?a aeine?aeaeaiiy.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee aeena?oaoe?eii? ?iaioe
i?aaenoaaeai? o aeaeyae? aeiiia?aeae ia V Eiia?an? ea?ae?ieia?a Oe?a?ie
(Ee?a, 1997) oa ia ?anioae?eainuee?e iaoeia?e eiioa?aioe?? (Oa?e?a,
1994) ?acoeueoaoe oa aeniiaee ?iaioe aoee caneooai? oa iaaiai?ai? 25
/a?aiy 1998 ?ieo ia ni?euei?e iaoeia?e eiioa?aioe?? a?aeae?eaiue
?aai?iaoe?? oa ?ioaineaii? oa?ai??, aino?iai ?ioa?eoo i?iea?aea oa
a?aeiiaethaaeueiiai e?eoaaiiy Oe?a?inueeiai iaoeiai-aeine?aeiiai
?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea oa eaoaae?e
ea?ae?ieia?? oa ooieoe?iiaeueii? ae?aaiinoeee Ee?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E. Ooi?ea IIC Oe?a?ie.

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii n?i ae?oeiaaieo
?ia?o. *ioe?e noaoo? a «Oe?a?inueeiio ea?ae?ieia?/iiio aeo?iae?» oa o?e
oace aeiiia?aeae ia ?anioae?eainuee?e iaoeia?e eiioa?aioe?? (Oa?e?a,
1994) oa V Eiia?an? ea?ae?ieia?a Oe?a?ie (Ee?a, 1997).

No?oeoo?a aeena?oaoe??. Ci?no aeena?oaoe?? aeeeaaeaiee ia 120 noi??ieao
iaoeiiieniiai oaenoo ? neeaaea?oueny ?c anooio, iaeyaeo e?oa?aoo?e,
iienaiiy iaoa??ae?a oa iaoiae?a aeine?aeaeaiiy, ?icae?eo ?acoeueoao?a
aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e, nieneo aeei?enoaii? e?oa?aoo?e (175 aeaea?ae). ?iaioa
?ethno?iaaia 30 oaaeeoeyie oa 2 iaethieaie.

INIIAIEE CI?NO ?IAIOE

Ee?i?/ia oa?aeoa?enoeea oai?eo oa iaoiaeieia?y aeine?aeaeaiiy.

A oiae? i?iaaaeaiiy aeine?aeaeaiiy aoei ianoaaeaii 258 oai?eo ia
?oai?/io oai?iao na?oey (?ON), a oiio /ene? 201 oai?ee ia aino?ee
?ioa?eo i?iea?aea (A?I) oa 57 oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic
(I?EN). Na?aaei?e a?e oai?eo ia aino?ee ?ioa?eo i?iea?aea neeaa 52,1
?iee. Na?aae ianoaaeaieo oai?eo ia A?I 194 iaoe??ioa-/ieia?ee (96,5%), a
7 (3,5%) — ae?iee. Aino?ee ?ioa?eo i?iea?aea aoa o?ainio?aeueiei o 48,2%
ianoaaeaieo oai?eo, e?oiiiaiaieuaaei o 9,2% oai?eo, i?eeiaiaieuaaei o
2,4% oai?eo. Ia?aaeiy eieae?caoe?y ?ioa?eoo i?iea?aea a?aei?/aeanue o
45,7% oai?eo, caaeiy eieae?caoe?y — o 46,7% oai?eo, A?I
ia?aaeiuei-caaeiuei? eieae?caoe?? ?a?no?oaaany o 7,4% ianoaaeaieo
oai?eo. I?iaaaeaia oai?ei ia aino?ee ?ioa?eo i?iea?aea oa?ai?y aeeth/aea
aeei?enoaiiy i?o?ao?a (o 97,5% oai?eo), aaoa-aae?aiiaeieaoi??a (o 87,6%
oai?eo), ?ia?a?oi??a aia?ioaicei-ia?aoai?thth/iai oa?iaioo (o 23,8%
oai?eo), aaia??io, ani???io, i?e iayaiino? iieacaiue — ia?eioe/ieo oa
iaia?eioe/ieo aiaeaaoee?a, ae?o?aoee?a (o 25,8% oai?eo), a oaeiae
e?aeiea?io. Ie??i oeueiai, 34,3% oai?eo aoea i?iaaaeaia nenoaiia
o?iiaie?oe/ia oa?ai?y i?aia?aoaie no?aioie?iace, 12,9% oai?eo —
aioo??oiueiei?iia?iee o?iiaie?cen, a 4,4% oai?eo — ia?eooaiia
o?ainethi?iaeueia ei?iia?ia aia?iieanoeea.

Na?aaei?e a?e o a?oi? ianoaaeaieo oai?eo ia iino?ioa?eoiee
ea?ae?ineea?ic neeaaeaa 55,2 ?iee, ui ia a?ae??ciyeinue aeinoia??ii a?ae
a?oie oai?eo ia A?I (p>0,1). A?oia oai?eo ia iino?ioa?eoiee
ea?ae?ineea?ic oaeiae ia a?ae??ciyeanue a??ia?aeii a?ae a?oie oai?eo ia
A?I ca noaoaaei neeaaeii — 91,2% /ieia?e?a oa 8,8% ae?iie. Aeoiaey/e c
aeaieo ciai?oiuei? yeaeo?iea?ae?ia?aie oa aoiea?ae?ia?ao??,
iino?ioa?eoiee ea?ae?ineea?ic ia?aaeiuei? eieae?caoe?? aoa o 61,4%
oai?eo, caaeiuei? eieae?caoe?? — o 28,7% oai?eo, a ia?aaeiuei-caaeiuei?
eieae?caoe?? — o 10,5% oai?eo. Ia iiiaio i?iaaaeaiiy aeine?aeaeaiiy
oai?? ia iino?ioa?eoiee ea?ae?ineea?ic i?iaeiaaeoaaee io?eioaaoe
oa?ai?th aaoa-aae?aiiaeieaoi?aie (94,7% ianoaaeaieo oai?eo),
eia?a?oi?aie aia?ioaic?iia?aoai?thth/iai oa?iaioo (45,6% oai?eo),
i?o?aoaie (82,4% oai?eo), ani???iii, i?e iaiao?aeiino? — ae?o?aoeeaie
(35,9% ianoaaeaieo oai?eo)

AEiaeai oai?ee c /enea ianoaaeaieo ia iaea?aeoaaa aioea?eoi?/ieo
i?aia?ao?a IA, IC, III eean?a ca eeaneo?eaoe??th Vaughan–Williams (1984
?.) oa na?oeaaeo ae?eiceae?a. O aeiaaeeo aeei?enoaiiy aioea?eoi?/iiai
i?aia?aoo IA eeano (e?aeiea?io) o ainoi?iio ia??iae? ?ioa?eoo i?iea?aea
a?i a?aei?iyany ia iaio, i?ae ca o?e aeiae aei i?iaaaeaiiy i?ia?aiiaaii?
noeioeyoe?? oeoii/e?a na?oey.

On? oai??, aeeth/ai? a aeine?aeaeaiiy, i?aeeyaaee caaaeueiii?eeiyoiio
ee?i?/iiio, ?ino?oiaioaeueiiio oa eaai?aoi?iiio ianoaaeaiith c iae?eii
oa?aeoa?o oa aeeiai?ee ia?aa?ao iniiaiiai caoai?thaaiiy (aino?ee ?ioa?eo
i?iea?aea /e iino?ioa?eoiee ea?ae?ineea?ic). O oai?eo ia A?I ia ae?oaiio
oeaei? caoai?thaaiiy i?ney noaa?e?caoe?? caaaeueiiai noaio oa ciie
iae?ico i?iea?aea ia oii? i?iaeiaaeaiiy aacenii? oa?ai?? i?iaiaeeeinue
?iaaceaia yeaeo?io?c?ieia?/ia aeine?aeaeaiiy na?oey (AOAe). O oai?eo ia
iino?ioa?eoiee ea?ae?ineea?ic ?iaaceaia AOAe na?oey i?iaiaeeeinue oaeiae
i?ney noaa?e?caoe?? caaaeueiiai noaio oa i?iaaaeaiiy iiaiiai
ia?iaaceaiiai ianoaaeaiiy ia oii? i?ae?a?aii? aacenii? oa?ai??.
Aeaeo?io?c?ieia?/ia aeine?aeaeaiiy i?iaiaeeeinue i?e ii?iaeueiiio ??ai?
aeaeo?ie?o?a o ieaci? e?ia?. Iaia’yceiaith oiiaith i?iaaaeaiiy
?iaaceaiiai AOAe na?oey aoea aeia?ia?eueia ?ioi?iiaaia caiaea oai?iai.

Iniiaiei aoaiii ?iaaceaiiai aeaeo?io?c?ieia?/iiai aeine?aeaeaiiy
yaeyeanue i?ia?aiiaaia noeioeyoe?y oeoii/e?a na?oey, i?ioieie yei? aoa
?ic?iaeaiee ia i?aenoaa? cai?iiiiiaaiiai P. Brugada c ni?aaaoi?aie oa
ia?aaeaa/aa noeioeyoe?th oeoii/e?a c aa?o?aee i?aaiai oeoii/ea, a i?e
caaei?e eieae?caoe?? aiaieua ?ioa?eoo i?iea?aea — ? c o?aeoo a?aeoieo
i?aaiai oeoii/ea iine?aeiaii iaeiei, aeaiia oa o?ueiia aeno?anoeioeaie
ia oii? iaa’ycaiiai aaceniiai ?eoio noeioeyoe?? c ?ioa?aaeii i?ae
?iioeuenaie 600 inae, a iio?i 430 inae, c iinooiiaei ciaioaiiyi
?ioa?aae?a c/aieaiiy aeno?anoeioe?a ia 20-10 inae aei aeinyaiaiiy
?ao?aeoa?iino? oeoii/e?a aai ?iaeoeoe?? no?eei? oeoii/eiai? oao?ea?ae??.
E?ioeaaith oi/eith i?ioieieo aaaaeaee aeinyaiaiiy ?ao?aeoa?iino?
oeoii/e?a aai ?iaeoeoe?th no?eei? oeoii/eiai? oao?ea?ae??.

On? ?iaeoeiaai? oeoii/eia? oao?ea?ae?? eeaneo?eoaaee ye no?ee? aai
iano?ee?, iiiiii?oi? aai iie?ii?oi?. No?eeeie aaaaeaee ia?ienecie
oeoii/eiai? oao?ea?ae?? o?eaae?noth 30 nae oa a?eueoa, a oaeiae o
noi?iaiae? oaeaeeiai oa ae?aaeaiiai ii?ooaiiy aaiiaeeiai?ee ? oiio
aeiaaath/eie iaaaeiiai eoioaaiiy. Iano?eeeie aaaaeaee ia?ienecie
oeoii/eiai? oao?ea?ae?? o?eaae?noth a?eueoa 6 eiiieaen?a QRS, aea ia
a?eueoa 30 nae, ye? eoioaaeenue niiioaiii. Iiiiii?oieie aaaaeaee
oeoii/eia? oao?ea?ae?? c iaci?iaiith oi?iith eiiieaen?a QRS o eiaeiiio
?c ca?a?no?iaaieo a?aeaaaeaiue ciai?oiuei? YEA. Iie?ii?oieie aaaaeaee
oeoii/eia? oao?ea?ae?? ?c ci?iiith a iaeiiio ? oiio ae a?aeaaaeaii?
ciai?oiuei? YEA oi?iith eiiieaena QRS /e ?c ci?iiei iai?yieii
yeaeo?e/ii? in? na?oey.

Ia?aiao?e aioo??oiueina?oeaai? aaiiaeeiai?ee oa nei?ioeeao caeaoi?noue
i?iea?aea ioe?ithaaee aaciina?aaeiuei ia?aae i?iaaaeaiiyi YOAe na?oey
iaoiaeii aeaii??ii? yoiea?ae?ia?ao??, neio?ii?ciaaii? c YEA.
Aeei?enoiaoaaany yoiea?ae?ia?ao “Toshiba Sonolayer SSH 40 A” (ssiii?y),
ia’?i e?aiai oeoii/ea na?oey i?ae /an nenoiee oa ae?anoiee aecia/aany
iaoiaeii “ieiua-aeiaaeeia”, ca?aeii c ?aeiiaiaeaoe?yie Aia?eeainueei?
anioe?aoe?? na?oey.

Aeine?aeaeaiiy aeaeo?ie?o?a e?ia? cae?enithaaee ia aiae?caoi??
«Eiaan-Oa?a 2» (Oaaeoea??y).

?acoeueoaoe aeine?aeaeaiiy aoee noaoenoe/ii ia?iaeai? ?c aeei?enoaiiyi
t-e?eoa??y Nouethaeaioa ia AII ?AI ?NAO 386 ca aeiiiiiaith iaeaoa
noaoenoe/ieo i?ia?ai. A?aei?iiino? i?ae ii??aithaaieie a?oiaie
aaaaeaeenue aeinoia??ieie i?e p<0,05. ?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy. I?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey o 201 oai?iai ia aino?ee ?ioa?eo i?iea?aea oeoii/eiaa oao?ea?ae?y aoea ?iaeoeiaaia o 64 oai?eo (31,8%), ye? aoee aeae?eai? a 1-oo a?oio. 2-ao a?oio neeaee 137 oai?eo A?I (68,2% a?ae caaaeueii? e?eueeino? oai?eo), o yeeo i?e i?iaaaeaii? INON oeoii/eiaa oao?ea?ae?y ia aoea ?iaeoeiaaia. Aeyaeaii, ui a 1-e a?oi? aeinoia??ii a?eueoa oai?eo iaee iiaoi?iee A?I c o?ii?/ieie aiaa?eciaiee na?oey: 10,2% i?ioe 1,1% oai?eo a 2-e a?oi? (p<0,01), a oaeiae ia?aiineee coieieo e?iaiia?ao 10,2% oa 1,1% aeiaaee?a a?aeiia?aeii (p<0,01). I?ae 1-th oa 2-th a?oiaie aecia/aia aeinoia??ia ??cieoey i?ae /an ioe?iee ee?i?/ieo i?iya?a aeenooieoe?? e?aiai oeoii/ea. Oae, ia 10 aeiao A?I aino?a e?aioeoii/eiaa iaaeinoaoi?noue II eeano ca T. Killip niinoa??aaeanue o 22 ?c 64 oai?eo 1-? a?oie, oiae? eiee o 2-e a?oi? a?aeiia?aeiee nooi?iue AEOI aeyaeaiee a oeae oa?i?i o?euee? o 11 c 137 iaoe??io?a (34,3% o 1-e a?oi? i?ioe 8,0% o 2-e, p<0,02). O oai?eo 1-a?oie a ia?o? 10 ae?a A?I aeinoia??ii /ano?oa ?a?no?oaaeenue niiioaii? ia?ienecie oeoii/eiai? oao?ea?ae?? (o 40,6% oai?eo 1-? a?oie i?ioe 4,37% 2-? (p<0,001), aeei?enoiaoaaeenue ae?o?aoeee (o 48,5% aeiaaee?a o 1-e a?oi? i?ioe 25,2% o 2-e, p<0,01), ui iiynith?oueny a?eueoei ?iniianthaeaeaiiyi aino?i? e?aioeoii/eiai? iaaeinoaoiino? (AEOI) na?aae oai?eo 1-? a?oie. Caa?oa? ia naaa oaaao oie oaeo, ui /anoioa ?iaeoeiaaiino? OO i?e i?iaaaeaii? INON o a?oi? oai?eo aino?ei ?ioa?eoii i?iea?aea c? niiioaiieie ia?ieneciaie oeoii/eiai? oao?ea?ae?? aoea 76,9 % (?iaeoeoe?y OO aeieeea o 20 c 26 oai?eo), ui aeinoia??ii aeua, i?ae /anoioa ?iaeoeoe?? OO i?e i?iaaaeaii? aeine?aeaeaiiy o an?e aeai?oe? oai?eo c A?I (?iaeoeoe?y OO a?aecia/aeanue o 64 oai?eo c 201, ui neeaei 31,8%, p<0,001). A caeaaeiino? a?ae aeaeo ?iaeoeiaaii? i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey oeoii/eiai? oao?ea?ae?? on? oai?? 1-? a?oie aoee a?aeianai? aei iaei??? c /ioe?ueio i?aea?oi (?en. 1). picscalex100010009000003b80b00000800420100000000050000000902000000000500 00000102ffffff000400000004010d000400000002010200050000000c025b010f020300 00001e00040000002701ffff030000001e00040000002701ffff050000000b0200000000 030000001e00050000000102ffffff0005000000090200000000040000002701ffff0300 00001e00050000000102ffffff00050000000902000000000700000016045b010f020000 0000040000002701ffff030000001e00050000000102ffffff0005000000090200000000 0700000016045b010f0200000000040000002701ffff030000001e00050000000102ffff ff0005000000090200000000070000001604550109020600060009000000fa0200000100 0000000000002200040000002d0100000400000004010d00040000000201020008000000 26060f000600ffffffff000009000000fa02050000000000ffffff002200040000002d01 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0102ffffff00040000002d01050007000000160423018d0108012101040000002d010700 040000002d0107000400000004010d0004000000020101000b000000320a0a0121010800 000034312520d1ccd8d2040000002701ffff030000001e00050000000102ffffff000500 00000902000000000700000016045b010f0200000000040000002d010600040000002d01 0500040000002d010200040000002d010100070000001b04200187000701140004000000 2d010500040000002d010600040000002d010100040000002d0102000500000009020000 0000050000000102ffffff00040000002d0105000700000016041e018200080118000400 00002d010700040000002d0107000400000004010d0004000000020101000b000000320a 0a0118000800000032322520d1cfd8d2040000002701ffff030000001e00050000000102 ffffff00050000000902000000000700000016045b010f0200000000040000002d010600 040000002d01050005000000090200000000050000000102ffffff00040000002d010500 040000002701ffff050000000c025b010f02030000001e00050000000102ffffff000500 0000090200000000040000002701ffff050000000b0200000000030000001e0005000000 0102ffffff0005000000090200000000040000002701ffff030000000000 ?en. 1 A?aenioeiaa ni?aa?aeiioaiiy aeae?a oeoii/eiaeo oao?ea?ae?e, ?iaeoeiaaieo i?e INON, o oai?eo ia A?I 1A (26 oai?eo) c ?iaeoeoe??th i?e i?iaaaeaii? INON no?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?? (NIOO), 1A (14 oai?eo), o yeeo aoea ?iaeoeiaaia no?eea iie?ii?oia oeoii/eiaa oao?ea?ae?y (NIOO), 1A (15 oai?eo) c ?iaeoeoe??th i?e i?iaaaeaii? INON iano?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?? (INIOO) oa 1A (9 oai?eo) c ?iaeoeoe??th iano?eei? iie?ii?oii? oeoii/eiai? oao?ea?ae?? (INIOO). Aeyaeaii, ui o oai?eo, ye? ia?aianee niiioaii? ia?ienecie OO, no?eea iiiiii?oia oeoii/eiaa oao?ea?ae?y ?iaeoeoaaeanue aeinoia??ii /ano?oa (42,3% aeiaaee?a i?ioe 12,9% (p<0,001) I?ae /an aiae?co aiaiianoe/ieo aeaieo aeyaeaii, ui oai?? c ?iaeoeoe??th (INIOO) (1A i?aea?oia) aeinoia??ii /ano?oa, i?ae oai?? aac ?iaeoeoe?? OO (2 a?oia) no?aaeaeaee a?ae a?ia?oii?/ii? oai?iae: 66,6% i?ioe 26,9% (p<0,01). Aeieaaee i?aeie io/ea A?na aeinoia??ii /ano?oa ?a?no?oaaeenue a 1A i?aea?oi? ii??aiyii c 2 a?oiith: 7,6% i?ioe 1,1% (p<0,05).O ii??aiyii? c oai?eie aac ?iaeoeoe?? OO o?ii?/i? aiaa?ecie na?oey aeinoia??ii /ano?oa ?a?no?oaaeenue a 1A i?aea?oi? (11,5% i?ioe 1,1%, p<0,01) oa a 1A i?aea?oi? (14,2% i?ioe 1,1%, p<0,002). Oai??, o yeeo i?e i?iaaaeaii? INON ?iaeoeoaaeanue no?eea oeoii/eiaa oao?ea?ae?y, aeinoia??ii /ano?oa, i?ae oai?? aac ?iaeoeoe?? OO, ia?aiineee ai?ciaee coieiee e?iaiia?ao. Oae, a 1A i?aea?oi? (c ?iaeoeoe??th no?eei? iiiiii?oii? OO) oae? ai?ciaee aoee ca?a?no?iaai? o 7,6% oai?eo i?ioe 1,1% a 2 a?oi? (p<0,05), a 1A i?aea?oi? (c ?iaeoeoe??th no?eei? iie?ii?oii? OO) o 14,2% i?ioe 1,1% (p<0,002). Aeey oai?eo c ?iaeoeoe??th iano?eeeo OO oaei? caeiiii??iino? ia aeyaeaii. I?ae /an aiae?co aeeaeie A?I aeyaeaii, ui eeoa a 1A i?aea?oi? o ii??aiyii? c 2 a?oiith aeinoia??ii /ano?oa aoa ca?a?no?iaaiee o?ainio?aeueiee ?ioa?eo i?iea?aea (76,9% i?ioe 43,0%, p<0,002) ?, a?aeiia?aeii, aeinoia??ii ??aeoa -e?oiiiaiaieuaaee ?ioa?eo i?iea?aea (23,0% i?ioe 53,5%, p<0,01). A 1A i?aea?oi?, ui oaeiae ia a?ae??ciyeanue aeinoia??ii a?ae 2 a?oie ca /anoioith ia?aaei?o oa caaei?o ?ioa?eo?a i?iea?aea, aeinoia??ii /ano?oa ?a?no?oaaeenue A?I ia?aaeiuei-caaeiuei? eieae?caoe?? (21,4% i?ioe 6,5% a 2 a?oi?, p<0,05), a a 1A i?aea?oi? aeinoia??ii /ano?oa ?icaeaaeenue aino?? aiaa?ecie na?oey (34,6% i?ioe 16,2%, p<0,05). ?aiiy iino?ioa?eoia noaiiea?ae?y ia oieoaeueiiio aoai? aeinoia??ii /ano?oa, ii??aiyii c 2 a?oiith, ?a?no?oaaeanue o oai?eo 1A (40,0% i?ioe 17,5%, p <0,05) oa 1A (44,4% i?ioe 17,5%, p<0,05) i?aea?oi, oiae? ye aeey ?aooe i?aea?oi 1 a?oie aeinoia??ii? ??cieoe? ca oeei iieacieeii ia aeyaeaii. Ao??iaaio?eeoey?i? aeieaaee aeinoia??ii /ano?oa, o ii??aiyii? c 2 a?oiith, ?a?no?oaaeenue o oai?eo 1A i?aea?oie (44,4% i?ioe 14,5%, p<0,02). Ia 10 aeiao A?I ?iciianthaeaeaii?noue aino?i? e?aioeoii/eiai? iaaeinoaoiino? II eeano ca T. Killip aoea aeinoia??ii aeuith ii??aiyii c 2 a?oiith oai?eo a 1A i?aea?oi? (30,7% i?ioe 8,0%, p<0,001), a 1A i?aea?oi? (42,8% i?ioe 8,0%, p<0,001) oa a 1A i?aea?oi? (40,0% i?ioe 8,0%, p<0,001), oiae? ye aeey 1A i?aea?oie iiae?ai?o aeinoia??ieo a?aei?iiinoae ia aeyaeaii. Aeinoia??ia ??cieoey ciaeaeaia i?e ii??aiyii? iieaciee?a aioo??oiueina?oeaai? aaiiaeeiai?ee a a?oi? oai?eo aac ?iaeoeoe?? OO c aeayeeie i?aea?oiaie 1 a?oie. Oae, a 1A i?aea?oi?(c ?iaeoeoe??th no?eei? iiiiii?oii? OO) o ii??aiyii? c 2 a?oiith aoa aeinoia??ii aeuei e?ioeaai-ae?anoie?/iee ?iaeaen (105,06,2 ie/i2 i?ioe 89,12,0 ie/i2, p<0,002) oa e?ioeaai-nenoie?/iee ?iaeaen (63,15,1 ie/i2 i?ioe 52,41,8ie/i2, p<0,02), oiae? ye o?aeoe?y aeeeaeo e?aiai oeoii/ea ? na?oeaaee ?iaeaen aeinoia??ii ia a?ae??ciyeenue. 1A i?aea?oia (c ?iaeoeoe??th i?e INON iano?eei? iiiiii?oii? OO) aeinoia??ii a?ae??ciyeanue a?ae 2 a?oie ca aaee/eiith e?ioeaai-ae?anoie?/iiai ?iaeaena(101,85,8 ie/i2 i?ioe 89,12,0 ie/i2, p<0,05). A 1A i?aea?oi? (c ?iaeoeoe??th iano?eei? iie?ii?oii? OO) o ii??aiyii? c 2 a?oiith (aac ?iaeoeoe?? OO i?e i?iaaaeaii? INON) aoea aeinoia??ii ieae/ith o?aeoe?y aeeeaeo e?aiai oeoii/ea (34,84,3% i?ioe 42,11,0%, p<0,05),?aooa ae ia?aiao??a aaiiaeeiai?ee ia iaea aeinoia??ii cia/eieo a?aei?iiinoae. A?aoiaoth/e iniaeeaa ee?i?/ia oa i?iaiinoe/ia cia/aiiy niiioaiieo ia?ieneci?a oeoii/eiai? oao?ea?ae??, iaie c iaoith aea/aiiy aieeao aaiiaeeiai?/ieo iieaciee?a ia oi?ioaaiiy a?eoiiaaiiiai noano?aoo o oai?eo ia A?I aoei i?iaaaeaii ii??aiyiiy ia?aiao??a aioo??oiueina?oeaai? aaiiaeeiai?ee a a?oiao oai?eo ?c niiioaiieie OO oa aac niiioaiieo OO, aea c ?o ?iaeoeoe??th i?e i?iaaaeaii? INON. I?e oeueiio aeyaeaii, ui e?ioeaai-ae?anoie?/iee ?iaeaen neeaa o oeeo a?oiao a?aeiia?aeii 106,07,7 ie/i2 ? 106,85,8ie/i2, (p>0,1), e?ioeaai-nenoie?/iee ?iaeaen — 66,06,61
ie/i2 oa 63,26,2 ie/i2 (p>0,1), o?aeoe?y aeeeaeo e?aiai oeoii/ea —
39,52,2% ? 38,22,2% (p>0,1), na?oeaaee ?iaeaen — 2,90,2 e/oa/i2 oa
2,70,2 e/oa/i2 (p>0,1). Oaeei /eiii, aeinoia??ieo a?aei?iiinoae ca
i?iaiae?ciaaieie iieacieeaie i?ae ii??aithaaieie a?oiaie oai?eo ia
ciaeaeaii.

Oaeiae aeyaeaii, ui a?oia oai?eo ia A?I ?c niiioaiieie ia?ieneciaie OO
ia iaea aeinoia??ieo a?aei?iiinoae i? ca iaeiei ?c i?iaiae?ciaaieo
ia?aiao??a aaiiaeeiai?ee a?ae 1A i?aea?oie (oai?? c ?iaeoeoe??th no?eei?
iiiiii?oii? OO i?e i?iaaaeaii? INON)- o an?o aeiaaeeao (p>0,1).

A oie aea /an ciaeaeai? aeinoia??i? a?aei?iiino? ia?aiao??a
aaiiaeeiai?ee i?e ii??aiyii? a?oie oai?eo c? niiioaiieie ia?ieneciaie
oeoii/eiai? oao?ea?ae?? a aino?iio ia??iae? ?ioa?eoo i?iea?aea c 2
a?oiith oai?eo (aac ?iaeoeoe?? OO i?e i?iaaaeaii? i?ia?aiiaaii?
noeioeyoe?? oeoii/e?a na?oey). Oae, o a?oi? oai?eo ?c niiioaiieie
ia?ieneciaie OO aoa aeinoia??ii aeuei e?ioeaai-ae?anoie?/iee ?iaeaen
(106,07,7 ie/i2 i?ioe 89,12,0 ie/i2, p<0,01) oa e?ioeaai-nenoie?/iee ?iaeaen (66,06,61 ie/i2 i?ioe 52,41,8ie/i2, p<0,01), oiae? ye o?aeoe?y aeeeaeo e?aiai oeoii/ea oa na?oeaaee ?iaeaen a oeeo a?oiao aeinoia??ii ia a?ae??ciyeenue I?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey o 57 oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic aoee aeae?eai? aea? a?oie oai?eo. 29 oai?eo (50,8% a?ae caaaeueii? e?eueeino? ianoaaeaieo) c ?iaeoeoe??th i?e i?iaaaeaii? INO oeoii/eiai? oao?ea?ae?? neeaee 3 a?oio, a 28 oai?eo (49,2% a?ae caaaeueii? e?eueeino? ianoaaeaieo), o yeeo oeoii/eiaa oao?ea?ae?y ia aoea ?iaeoeiaaia — 4 a?oio. Na?aaei?e a?e oai?eo 3 a?oie neeaa 56,22,4 ?iee, ui ia a?ae??ciyeinue aeinoia??ii a?ae na?aaeiueiai a?eo oai?eo a 4 a?oi? — 54,33,1 ?iee (p>0,1). 3 oa 4 a?oie aoee ni?anoaaeai? ca noaoaaei neeaaeii: /ieia?ee
neeaee 93,1% a 3 a?oi? i?ioe 89,2% a 4 a?oi? (p>0,1), ae?iee
a?aeiia?aeii — 6,9% a 3 a?oi? i?ioe 10,8% a 4 a?oi? (p>0,1).

I?ae /an aiae?co aiaiianoe/ieo aeaieo aeyaeaii, ui c /enea oai?eo 3
a?oie coieieo e?iaiia?ao ?ai?oa ia?aianee 20,6% oai?eo, ui ia
a?ae??ciyeinue aeinoia??ii a?ae aiaeia?/iiai iieacieea a 4 a?oi? — 17,8%
oai?eo (p>0,1). A oie aea /an o oai?eo 3 a?oie aeinoia??ii /ano?oa, i?ae
a 4 a?oi?, ?a?no?oaaeenue niiioaii? ia?ienecie oeoii/eiai? oao?ea?ae??
(48,2% i?ioe 10,7%, p<0,01). Caa?oa? ia naaa oaaao oa, ui a a?oi? oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic, ye? a aiaiiac? iaee niiioaii? ia?ienecie oeoii/eiai? oao?ea?ae??, /anoioa ?iaeoeoe?? OO i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey aoea aeinoia??ii aeuith, i?ae o an?e a?oi? oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic ? neeaea 94,1% i?ioe 50,8% (p<0,001). A caeaaeiino? a?ae aeaeo ?iaeoeiaaii? i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey oeoii/eiai? oao?ea?ae?? an? oai?? 3-? a?oie aoee a?aeianai? aei iaei??? c /ioe?ueio i?aea?oi (?en. 2). picscalex100010009000003f40b00000800a20100000000050000000902000000000500 00000102ffffff000400000004010d000400000002010200050000000c025b0177020300 00001e00040000002701ffff030000001e00040000002701ffff050000000b0200000000 030000001e00050000000102ffffff0005000000090200000000040000002701ffff0300 00001e00050000000102ffffff00050000000902000000000700000016045b0177020000 0000040000002701ffff030000001e00050000000102ffffff0005000000090200000000 0700000016045b01770200000000040000002701ffff030000001e00050000000102ffff ff0005000000090200000000070000001604550171020600060007000000fc0200008080 80000000040000002d01000009000000fa02000001000000000000002200040000002d01 010007000000fc020000ffffff000000040000002d010200050000000902ffffff000400 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6d01ed007001ed007601ed007901ec007c01ec008201eb008501eb008801ea008d01e900 9001e9009301e8009801e7009b01e7009d01e600a201e500a501e500a701e400ac01e300 af01e200b101e200b501e100b801e000ba01df00be01de00c001dd00c201dd00c601db00 c701da00c901da00cc01d800ce01d800d001d700d301d500d401d400d401a00007000000 fc020000969696008020040000002d01060004000000f0010500050000000902ffffff00 05000000010296969600d600000024036900d401a000d301a100d001a300ce01a400cc01 a400c901a600c701a600c601a700c201a900c001a900be01aa00ba01ab00b801ac00b501 ad00b101ae00af01ae00ac01af00a701b000a501b100a201b1009d01b2009b01b3009801 b3009301b4009001b5008d01b5008801b6008501b7008201b7007c01b8007901b8007601 b9007001b9006d01b9006a01ba006401ba006001bb005d01bb005701bb005401bb005001 bc004a01bc004701bc004301bc003d01bc003a01bd003601bd003001bd002d01bd002901 bd002301bd001f01bd001c01bd001601bc001201bc000f01bc000901bc000501bc000201 bc00fc00bb00f800bb00f500bb00ef00ba00ec00ba00e900ba00e300b900e000b900dd00 b900d700b800d400b700d100b700cb00b600c800b600c500b500c000b400bd00b400ba00 b300b500b200b300b200b000b100ab00b000a900b000a600af00a200ae009f00ad009d00 ad009900ab009700ab009500aa009100a9008f00a8008d00a7008900a6008800a5008600 a4008300a3008100a2008000a1007d00a0007c009f007a009e0078009d0077009c002901 8c00d401a00009000000fa02000000000000000000002200040000002d01050004000000 2d010200040000002701ffff030000001e00040000002d010600040000002d0101000500 0000010296969600050000000902ffffff000700000016045b0177020000000004000000 2d010500040000002d010200040000002701ffff030000001e00040000002d0106000400 00002d01010005000000010296969600050000000902ffffff000700000016045b017702 0000000007000000fc020000000000000000040000002d01070004000000f00106000400 00002d01050004000000f00101000400000004010d002d000000f7000003140000000000 800000000080000080800000000080008000800000808000c0c0c000c0dcc000a6caf000 fffbf000a0a0a40080808000ff00000000ff0000ffff00000000ff00ff00ff0000ffff00 ffffff000400000034020100040000002d010400040000002d010300070000001b045400 74013300f300040000002d010700040000002d010500040000002d010300040000002d01 0400050000000902ffffff0005000000010296969600040000002d010700070000001604 52006f013400f70010000000fb02efff000000000000bc02000000cc0000002241726961 6c00cc00040000002d010600040000002d01060005000000090200000000050000000102 ffffff000400000004010d0004000000020101000c000000320a3600f700090000003238 2520cdd1ccd8d200040000002701ffff030000001e00050000000102ffffff0005000000 0902000000000700000016045b01770200000000040000002d010500040000002d010700 040000002d010400040000002d010300070000001b0420019e010401f300040000002d01 0700040000002d010500040000002d010300040000002d01040005000000090200000000 050000000102ffffff00040000002d0107000700000016041e0199010501f70004000000 2d010600040000002d0106000400000004010d0004000000020101000b000000320a0701 f7000800000033382520d1ccd8d2040000002701ffff030000001e00050000000102ffff ff00050000000902000000000700000016045b01770200000000040000002d0105000400 00002d010700040000002d010400040000002d010300070000001b04b4005d029600e701 040000002d010700040000002d010500040000002d010300040000002d01040005000000 090200000000050000000102ffffff00040000002d010700070000001604b20058029700 eb01040000002d010600040000002d0106000400000004010d0004000000020101000c00 0000320a9900eb010a00000031372520cdd1cfd8d220040000002701ffff030000001e00 050000000102ffffff00050000000902000000000700000016045b017702000000000400 00002d010500040000002d010700040000002d010400040000002d010300070000001b04 b5006d0096000700040000002d010700040000002d010500040000002d01030004000000 2d01040005000000090200000000050000000102ffffff00040000002d01070007000000 1604b300680097000b00040000002d010600040000002d0106000400000004010d000400 0000020101000b000000320a99000b000800000031372520d1cfd8d2040000002701ffff 030000001e00050000000102ffffff00050000000902000000000700000016045b017702 00000000040000002d010500040000002d01070005000000090200000000050000000102 ffffff00040000002d010700040000002701ffff050000000c025b017702030000001e00 050000000102ffffff0005000000090200000000040000002701ffff050000000b020000 0000030000001e00050000000102ffffff0005000000090200000000040000002701ffff 030000000000 ?en. 2 A?aenioeiaa ni?aa?aeiioaiiy aeae?a oeoii/eiaeo oao?ea?ae?e, ?iaeoeiaaieo i?e INON o oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic 3A (11 oai?eo) c ?iaeoeoe??th i?e i?iaaaeaii? INON no?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?o (NIOO), 3A (5 oai?eo), o yeeo aoea eiaeoeiaaia no?eea iie?ii?oia oeoii/eiaa oao?ea?ae?y (NIOO), 3A (8 oai?eo) c ?iaeoeoe??th iano?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?? (INIOO) oa 3A (5 oai?eo) c ?iaeoeoe??th iano?eei? iie?ii?oii? oeoii/eiai? oao?ea?ae?? (INIOO). O oai?eo ?c niiioaiieie ia?ieneciaie OO /anoioa ?iaeoeoe?? no?eeie iiiiii?oii? oeoii/eiai? oao?ea?ae?? aoea aeinoia??ii aeuith ? neeaea 68,7% (p<0,001). A i?aea?oiao oai?eo c ?iaeoeoe??th i?e i?iaaaeaii? INON no?eeeo oeoii/eiaeo oao?ea?ae?e aeinoia??ii /ano?oa ii??aiyii c 4 a?oiith oai?eo (aac ?iaeoeoe?? oeoii/eiaeo oao?a?eoi?e) ?ai?oa ?a?no?oaaeenue niiioaii? ia?ienecie OO: a 3A i?aea?oi? a 90,9% aeiaaee?a i?ioe 10,7% a 4 a?oi? (p<0,001), a 3A i?aea?oi? o 60,0% oai?eo i?ioe 10,7% a 4a?oi? (p<0,01). Aeey i?aea?oi c ?iaeoeoe??th i?e INON iano?eeeo OO oaeeo aeinoia??ieo a?aei?iiinoae a?ae 4 a?oie ia aeyaeaii. Aeinoia??i? a?aei?iiino? ciaeaeai? i?e ii??aiyii? iieaciee?a aioo??oiueina?oeaai? aaiiaeeiai?ee a?oie oai?eo aac ?iaeoeoe?? OO c 3A i?aea?oiith (?iaeoeoe?y i?e i?iaaaeaii? INON no?eei? iiiiii?oii? OO). Oae, a 3A i?aea?oi? ii??aiyii c 4 a?oiith aoa aeinoia??ii aeuei e?ioeaai-ae?anoie?/iee ?iaeaen (139,514,2 ie/i2 i?ioe 99,65,6 ie/i2, p<0,01), e?ioeaai-nenoie?/iee ?iaeaen (95,111,9 ie/i2 i?ioe 59,83,8 ie/i2, p<0,001), aeinoia??ii ieae/a o?aeoe?y aeeeaeo e?aiai oeoii/ea (32,41,9% i?ioe 41,61,7% p<0,01), oiae? ye na?oeaaee ?iaeaen aeinoia??ii ia a?ae??ciyany. A?aoiaoth/e iniaeeaa ee?i?/ia oa i?iaiinoe/ia cia/aiiy niiioaiieo ia?ieneci?a oeoii/eiai? oao?ea?ae??, iaie c iaoith aea/aiiy aieeao aaiiaeeiai?/ieo iieaciee?a ia oi?ioaaiiy a?eoiiaaiiiai noano?aoo o oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic aoei i?iaaaeaii ii??aiyiiy ia?aiao??a aioo??oiueina?oeaai? aaiiaeeiai?ee a a?oiao oai?eo c? niiioaiieie OO oa aac niiioaiieo OO, aea c ?o ?iaeoeoe??th i?e i?iaaaeaii? INON. I?e oeueiio e?ioeaai-ae?anoie?/iee ?iaeaen (EAe?) neeaa a oeeo a?oiao a?aeiia?aeii 120,412,2 ie/i2 ? 91,94,9 ie/i2 (p<0,05), e?ioeaai-nenoie?/iee ?iaeaen (EN?) — 76,59,4 ie/i2 ? 57,73,2 ie/i2 (p>0,05), o?aeoe?y aeeeaeo (OA) e?aiai oeoii/ea — 37,62,3% ?
39,21,5% (p>0,1), na?oeaaee ?iaeaen (N?) — 3,20,4 e/oa/i2 ? 2,40,2
e/oa/i2 (p>0,1). Oaeei /eiii, a a?oi? oai?eo c? niiioaiieie ia?ieneciaie
oeoii/eiai? oao?ea?ae?? aoa aeinoia??ii aeuei e?ioeaai-ae?anoie?/iee
?iaeaen, ca ?ioeie i?iaiae?ciaaieie iieacieeaie aeinoia??ieo
a?aei?iiinoae i?ae ii??aithaaieie a?oiaie oai?eo ia aeyaeaii. A?oia
oai?eo iino?ioa?eoiei ea?ae?ineea?icii c? niiioaiieie ia?ieneciaie OO ia
iaea aeinoia??ieo a?aei?i ca aeiaeiei c i?iaiae?ciaaieo ia?aiao??a
aaiiaeeiai?ee a?ae 3A i?aea?oie (oai?? c ?iaeoeoe??th no?eei?
iiiiii?oii? OO i?e i?iaaaeaii? INON)

I?eaaaeai? oaeoe aeicaieythoue ?icaeyaeaoe ?iaeoeoe?th i?e i?iaaaeaii?
INON o oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic no?eei? iiiiii?oii? OO ye
/eiiee,yeee ia? oa ae ee?i?/ia cia/aiiy, ui e aeyaeaiiy o oai?eo ia
iino?ioa?eoiee ea?ae?ineea?ic niiioaiieo ia?ieneci?a OO. Io?eiai? i?e
i?iaaaeaiiio aeine?aeaeaii? aeai? aeacothoue oaeiae ia oa, ui ye o a?oi?
oai?eo c? niiioaiieie ia?ieneciaie OO, oae ? a a?oi? c ?iaeoeoe??th
no?eei? iiiiii?oii? OO aoea aeinoia??ii a?eueo ae?aaeaia ae?eyoaoe?y
e?aiai oeoii/ea.

C iaoith aea/aiiy aieeao aaiiaeeiai?/ieo iieaciee?a ia oi?ioaaiiy
a?eoiiaaiiiai noano?aoo o oai?eo ia aino?ee ?ioa?eo i?iea?aea aoei
i?iaaaeaia ii??aiyiiy ia?aiao??a aioo??oiueina?oeaai? aaiiaeeiai?ee a
a?oiao c? niiioaiieie ia?ieneciaie oeoii/eiai? oao?ea?ae?? oa aac ieo,
aea c ?iaeoeoe??th OO i?e INON. Aeyaeaii, ui aeinoia??ieo a?aei?i ca
oeeie iieacieeaie i?ae ii??aithaaieie a?oiaie oai?eo iaia?, iaeiae
iaeaea? a?oie aeinoia??ii a?ae??ciyeenue a?ae a?oie oai?eo aac
?iaeoeoe?? oeoii/eiai? oao?ea?ae?? a?eueoeie aaee/eiaie
e?ioeaai-ae?anoie?/iiai oa e?ioeaai-nenoie?/iiai ?iaeaen?a.

A oie aea /an i?e ii??aiyii? aiaeia?/ieo iieaciee?a o oai?eo
iino?ioa?eoiei ea?ae?ineea?icii e?ioeaai-ae?anoie?/iee ?iaeaen aeyaeany
aeinoia??ii aeuei o a?oi? oai?eo c? niiioaiieie ia?ieneciaie oeoii/eiai?
oao?ea?ae?? o ii??aiyii? c a?oiith aac ieo, aea c iiceoeaiei
?acoeueoaoii INON. I?e oeueiio a?oia oai?eo c ?iaeoeoe??th OO i?e INON,
aea aac niiioaiieo ia?ieneci?a oeoii/eiai? oao?ea?ae??, ia
a?ae??ciyeanue aeinoia??ii ca ia?aiao?aie aaiiaeeiai?ee, ui
aiae?coaaeenue, a?ae a?oie c iaaaoeaiei ?acoeueoaoii i?ia?aiiaaii?
noeioeyoe?? oeoii/e?a na?oey.

Io?eiai? aeai? iiaeooue na?ae/aoe i?i oa, ui o oai?eo ia iino?ioa?eoiee
ea?ae?ineea?ic ae?eyoaoe?y ii?iaeieie e?aiai oeoii/ea na?oey aeeiio?
?ieue “ioneiaiai iaoai?cio” o ?aae?caoe?? aaea noi?iiaaiiai
a?eoiiaaiiiai noano?aoo oa aeieeiaii? niiioaiieo iaiaae?a oeoii/eiai?
oao?ea?ae??. Ia a?aei?io a?ae oeueiai, i?e aino?iio ?ioa?eo? i?iea?aea
ae?eyoaoe?y ii?iaeieie e?aiai oeoii/ea, aieeaath/e ia oi?ioaaiiy
a?eoiiaaiiiai noano?aoo, ia yaey?oueny “ioneiaei iaoai?ciii” eiai
?aae?caoe??, ine?eueee iieacieee aioo??oiueina?oeaai? aaiiaeeiai?ee o
a?oiao c? niiioaiieie ia?ieneciaie OO oa aac ieo, aea c iiceoeaiei
?acoeueoaoii INON, aeinoia??ii ia a?ae??ciythoueny.

AENIIAEE

1. I?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey oeoii/eia?
oao?ea?ae?? ?iaeoeothoueny o 32% oai?eo ia aino?ee ?ioa?eo i?iea?aea oa
o 51% oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic (?<0,05). O oai?eo c? niiioaiieie ia?ieneciaie oeoii/eiai? oao?ea?ae?? /anoioa ?? ?iaeoeoe?? aeinoia??ii aeua ? neeaaea? 77% na?aae oai?eo ia aino?ee ?ioa?eo i?iea?aea oa 94% na?aae oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic. 2. O oai?eo ia aino?ee ?ioa?eo i?iea?aea c ?iaeoeoe??th oeoii/eiai? oao?ea?ae?? /ano?oa, i?ae o oai?eo aac ?iaeoeoe??, ?a?no?othoueny o?ii?/i? aiaa?ecie na?oey (10,2% i?ioe 1,1%), ai?ciaee coieiee e?iaiia?ao (10,2% i?ioe1,1%), niiioaii? ia?ienecie oeoii/eiai? oao?ea?ae?? (40,6% i?ioe 4,4%) oa aino?a e?aioeoii/eiaa iaaeinoaoi?noue(34,4% i?ioe 8,0%). Iaoe??ioe c ?iaeoeoe??th no?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?? /ano?oa, i?ae oai?? aac ?iaeoeoe??, iaee o?ii?/i? aiaa?ecie na?oey (11,5% i?ioe 1,1%) oa coieieo e?iaiia?ao a aiaiiac? (7,7% i?ioe 1,1%), o oai?eo c ?iaeoeoe??th no?eei? iie?ii?oii? oeoii/eiai? oao?ea?ae?? oaeiae /ano?oa ?a?no?othoueny o?ii?/i? aiaa?ecie na?oey (14,3% i?ioe 1,1%) oa coieiee e?iaiia?ao a aiaiiac? (14,3% i?ioe 1,1%). 3. ?iaeoeoe?y no?eeeo oeoii/eiaeo oao?ea?ae?e i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey o oai?eo iino?ioa?eoiei ea?ae?ineea?icii aeicaiey? o 95% aeiaaee?a aeyaeyoe oai?eo c ai?ciaeaie niiioaiieo no?eeeo OO, a ?iaeoeoe?y iano?eeeo oeoii/eiaeo oao?ea?ae?e aeinoia??ii /ano?oa ?a?no?o?oueny o oai?eo c ?aiiueith iino?ioa?eoiith noaiiea?ae?ath, ui na?ae/eoue i?i ?ieue ?ac?aeoaeueii? ?oai?? o aaiac? aeacaieo a?eoi?e. 4. Oai?? c? niiioaiieie ia?ieneciaie oeoii/eiai? oao?ea?ae?? oa c ?iaeoeoe??th no?eei? iiiiii?oii? OO i?e i?iaaaeaii? i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey c?noaaeythoueny i?ae niaith ca aaiiaeeiai?/ieie ia?aiao?aie ye i?e aino?iio ?ioa?eo? i?iea?aea, oae ? i?e iino?ioa?eoiiio ea?ae?ineea?ic? ? oa?aeoa?ecothoueny iayai?noth ae?eyoaoe?? ii?iaeieie e?aiai oeoii/ea 5. Ae?anoie?/ia ae?eyoaoe?y e?aiai oeoii/ea o oai?eo ia aino?ee ?ioa?eo i?iea?aea ? oaeoi?ii oi?ioaaiiy a?eoiiaaiiiai noano?aoo, a i?e?aeiaiiy aei ia? ca?eueoaiiy ?ici???a na?oey i?ae /an nenoiee ni?ey? ?iaeoeiaaiino? no?eeeo iiiiii?oieo oeoii/eiaeo oao?ea?ae?e. O oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic o aaiac? oeueiai aeaeo a?eoi?e ia? cia/aiiy aeenooieoe?y e?aiai oeoii/ea ia oii? ca?eueoaiiy ia'?i?a na?oey. 6. O oai?eo c ?iaeoeoe??th iie?ii?oieo oeoii/eiaeo oao?ea?ae?e a?aenooi?e ?o ca'ycie c ae?eyoaoe??th ii?iaeieie e?aiai oeoii/ea, a ?a?no?aoe?y iano?eeeo oeoii/eiaeo oao?ea?ae?e o oai?eo ia aino?ee ?ioa?eo i?iea?aea niinoa??aa?oueny a a?oi? c? cieaeaiith o?aeoe??th aeeeaeo, ui ca oiiae /anoiai aeyaeaiiy o oeeo oai?eo ?aiiuei? iino?ioa?eoii? noaiiea?ae?? iiaea na?ae/eoe i?i ?oai?/iee aaiac oeueiai aeaeo a?eoi?e. 7. C?noaaeaii?noue ia?aiao??a aioo??oiueina?oeaai? aaiiaeeiai?ee o a?oi? oai?eo ia aino?ee ?ioa?eo i?iea?aea c iayai?noth niiioaiieo oeoii/eiaeo oao?ea?ae?e, a a?oi? c ?iaeoeoe??th no?eei? iiiiii?oii? oeoii/eiai? oao?ea?ae?? oa a a?oi? oai?eo c iayai?noth aeaeo?e/ii? ianoaa?eueiino? na?oey aac niiioaiieo ia?ieneci?a OO na?ae/aoue i?i i?ia?aeio ?ieue aaiiaeeiai?/ieo oaeoi??a o oi?ioaaii? a?eoiiaaiiiai noano?aoo, a oie /an ye i?e iino?ioa?eoiiio ea?ae?ineea?ic? ae?eyoaoe?y ii?iaeieie e?aiai oeoii/ea iiaea aooe iniiaiei ioneiaei iaoai?ciii o ?aae?caoe?? a?eoiiaaiiiai noano?aoo I?AEOE*I? ?AEIIAIAeAOe?? 1. I?iaaaeaiiy i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey ? aacia/iei iaoiaeii aeine?aeaeaiiy ? ?aeiiaiaeo?oueny oai?ei ia aino?ee ?ioa?eo i?iea?aea c iayai?noth aiaa?eci na?oey, ai?ciae?a coieiee e?iaiia?ao a aiaiiac?, iciae aino?i? e?aioeoii/eiai? iaaeinoaoiino?, yea o?eia?oueny aei 10-? aeiae caoai?thaaiiy, aeeeyoaoe?? ii?iaeieie e?aiai oeoii/ea ca aeaieie aeaii??ii? aoiea?ae?ia?ao?? c iaoith aeyaeaiiy a?eoiiaaiiiai noano?aoo caa?iceeaeo aeey aeeooy a?eoi?e. 2. A?aoiaoth/e oie oaeo, ui o 77% oai?eo ia aino?ee ?ioa?eo i?iea?aea oa o 94% oai?eo ia iino?ioa?eoiee ea?ae?ineea?ic ?c ca?a?no?iaaieie niiioaiieie iaiaaeaie oeoii/eiai? oao?ea?ae?? ?acoeueoao i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey aoa iiceoeaiei, eiai i?iaaaeaiiy c iaoith aeyaeaiiy aeaeo?e/ii? ianoaa?eueiino? i?iea?aea o aeaiiai eiioeiaaioo oai?eo iaaeioe?eueia. Iaoith ?iaaceaiiai yeaeo?io?c?ieia?/iiai aeine?aeaeaiiy o aeaiiio aeiaaeeo iiaea aooe eeoa eiio?ieue ca aaeaeaaoi?noth e?eoaaiiy. 3. I?iaieoaaiiy i?ae /an i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey iie?ii?oieo oeoii/eiaeo oao?ea?ae?e ? i?aenoaaith aeey cae?eniaiiy oe?eani?yiiaaieo caoiae?a aeey iie?auaiiy aioo??oiueiei?iia?iiai e?iaiia?ao (aeeth/ath/e o??o?a?/i? ao?o/aiiy), a i?e ?iaeoeoe?? iiiiii?oieo oao?ea?ae?e iaiao?aeia oa?ai?y, ni?yiiaaia ia ciaioaiiy ?ici???a ii?iaeieie e?aiai oeoii/ea. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Ia?oiiaiei A.I., E?eei I.E., Iiiia A.?., ?ooeaiei N.I., Aioiiia A.ss. Eeeieei-aaiiaeeiaie/aneay oa?aeoa?enoeea aieueiuo ino?ui eioa?eoii ieiea?aea n yeaeo?e/aneie ianoaaeeueiinoueth na?aeoea // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae.- 1994.- ? 2.- N. 17-22. 2.Aia?ia A.A., Ia?oiiaiei A.I., E?eei I.E., Iiiia A.?., ?ooeaiei N.I., Aioiiia A.ss. I?eiaiaiea iaia?aiii?ioaeoi?ia i?e ino?ii eioa?eoa ieiea?aea: aicaeaenoaea ia yeaeo?e/aneoth ianoaaeeueiinoue na?aeoea e aaiiaeeiaieeo // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae.- 1996.- ? 3.- N.24-28. 3. Ia?oiiaiei A.I., E?eei I.E., Ouii/ei I.I., Eooie? N.I., ?ooeaiei N.I.,AEo?eei O.A. Iniaaiiinoe yeaeo?ioeceieiae/aneeo yooaeoia aioea?eoie/aneeo i?aia?aoia I e III eeannia o aieueiuo EAN, ia?aianoeo eioa?eo ieiea?aea // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae.-1997.- ? 3.- N.7-12. 4. Aecye A.A., Aai?ia E.TH., Aieuiaoe A.ss., Oaaeioeia E.I., Ai?iuoe A.A., O?eoiiiaa I.I., Eieiieaoe A.A., Aaeea? A.O., Aaeeia A.TH., Ieoaeue/aiei I.E., Aia?ia A.A., Ia?oiiaiei A.I., E?eei I.E., ?ooeaiei N.I., Aiiniaa A.I., I?oaeeee E.A., Eoaeeae A.Ae., Naaeei A.A., Iaoyaeaiei A.C., No?iaaiiaa I.A., Ieaiiaa I.I., Eaioei I.A., Aa?aaiiiae/ I.I., Oaeiee A.O., Iaaeee N.N., *a?eaaneee A.A., sseiaeia E.ss., *oao/iay E.E., *oao/iue A.I., Iaeay E.O., Eiieoea I.I., Ca?ea/aoeeay E.O., Eauaiei A.A., Aeueoi ss.A., Eiiiiinia N.I., A?eoeia A.E. Ia?aue iiuo i?eiaiaiey oeaiaaiai aeoeaaoi?a ieacieiiaaia i?e eioa?eoa ieiea?aea a Oe?aeia: aeaiiua iiiaioeaio?iaiai enneaaeiaaiey // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae.-1997.- ? 3.- N.51-56. 5. Ia?oiiaiei A.I., E?eei I.E., Iiiia A.?., ?ooeaiei N.I Yeaeo?ioeceieiae/aneea yooaeou yeciaaiiiai oinoie?aaoeia (iaioiia) o aieueiuo ino?ui eioa?eoii ieiea?aea // Oac. aeiee. ?anioaeeeaineie iao/iie eiioa?aioeee "Aeooaeueiua aii?inu iaoiaaiaca, aeeaaiinoeee e ea/aiey aoa?ineea?ica e eoaie/aneie aieacie na?aeoea."-Oa?ueeia.- 1994.- N.162. 6. Ia?oiiaiei A.I., E?eei I.E., Iiiia A.?., ?ooeaiei N.I. Eeeie/aneay oa?aeoa?enoeea aieueiuo ino?ui eioa?eoii ieiea?aea, ineiaei?iiui yeaeo?e/aneie ianoaaeeueiinoueth na?aeoea // Oac. aeiee. ?anioaeeeaineie iao/iie eiioa?aioeee "Aeooaeueiua aii?inu iaoiaaiaca, aeeaaiinoeee e ea/aiey aoa?ineea?ica e eoaie/aneie aieacie na?aeoea."-Oa?ueeia.- 1994.- N. 162-163. 7. A?ueue AE.A., Ia?oiiaiei A.I., Oeey? E.A., Iiiia A.?., Oieiaeaiei I.I., ?ooeaiei N.I. I?ioeeaeoeea ?aiiaeaee?iaaiey eaaiai aeaeoaei/ea o aieueiuo n eioa?eoii ieiea?aea n iiiiuueth i?aaeoeoaea // Iaoa?eaeu V eiia?anna ea?aeeieiaia Oe?aeiu.- Eeaa.- 1997.- N.72. AIIOAOe?ss ?ooeaiei N.I. Aaiiaeeiai?/i? aeaoa?i?iaioe aeaeo?e/ii? ianoaa?eueiino? na?oey o oai?eo ia ?ON, ye? ia?aianee ?ioa?eo i?iea?aea. — ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.11 — ea?ae?ieia?y. ?inoeooo ea?ae?ieia?? ?i. aeaae. I.Ae. No?aaeanea AII Oe?a?ie, Ee?a, 1999. Ianoaaeaii 258 oai?eo ia ?ON (201 ia aino?ee ?ioa?eo i?iea?aea, 57 ia i?ney?ioa?eoiee ea?ae?ineea?ic) c i?iaaaeaiiyi i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey oa aeaii??ii? aoiea?ae?ia?ao??. Aeyaeai? ee?i?/i? oa aaiiaeeiai?/i? oaeoi?e, ui ni?eythoue aeieeiaiith aeaeo?e/ii? ianoaa?eueiino? na?oey o aeaii? eaoaai??? oai?eo. Ooi/iai? iieacaiiy aei i?iaaaeaiiy i?ia?aiiaaii? noeioeyoe?? oeoii/e?a na?oey. Eeth/ia? neiaa: ?ioa?eo i?iea?aea, i?ia?aiiaaia noeioeyoe?y oeoii/e?a na?oey, aeaeo?e/ia ianoaa?euei?noue na?oey. ANNOTATION Rukchlenko S.N Haemodynamic determinants of electric instability of the heart in CAD patients survived after myocardial infarction. Institute of Cardiology acad N.D. Strazhesko AMS Ukrainian, Kiev, 1999. Ukrainian. 258 patients with CAD (201 with acute myocardial infarction and 57 with postinfarction cardiosclerosis) in whom programmed ventricular stimulation and 2-D echocardiography were performed. Clinical and haemodynamic factors leading to electric instability of the myocardium in this group of patients were determined. Indications for the programmed ventricular stimulation were developed. Key words: acute myocardial infarction, programmed ventricular stimulation, electric instability of the myocardium. AIIIOAOeEss ?ooeaiei N.I. Aaiiaeeiaie/aneea aeaoa?ieiaiou yeaeo?e/aneie ianoaaeeueiinoe na?aeoea o aieueiuo EAN, ia?aianoeo eioa?eo ieiea?aea. — ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.11-ea?aeeieiaey. Einoeooo ea?aeeieiaee ei. aeaae. I.Ae. No?aaeanei AII Oe?aeiu, Eeaa, 1999. I?e i?iaaaeaiee i?ia?aiie?oaiie noeioeyoeee aeaeoaei/eia na?aeoea o 201 aieueiiai ino?ui eioa?eoii ieiea?aea aeaeoaei/eiaay oaoeea?aeey auea eiaeooee?iaaia o 64 aieueiuo, /oi ninoaaeei 31,8% io iauaai /enea ianeaaeiaaiiuo aieueiuo n IEI. *anoioa eiaeoeoeee AEO i?e i?iaaaeaiee INAEN a a?oiia aieueiuo ino?ui eioa?eoii ieiea?aea ni niiioaiiuie ia?ieneciaie aeaeoaei/eiaie oaoeea?aeee ninoaaeea 76,9% (eiaeoeoeey AEO ioia/aeanue o 20 ec 26 aieueiuo), /oi aeinoiaa?ii auoa, /ai ai anae auai?ea aieueiuo n IEI (p<0,001). O 26 aieueiuo i?e i?iaaaeaiee INAEN auea eiaeooee?iaaia noieeay iiiiii?oiay aeaeoaei/eiaay oaoeea?aeey, /oi ninoaaeei 40,6% io eiee/anoaa aieueiuo n eiaeoeoeeae AEO eee 12,9% io anao ianeaaeiaaiiuo aieueiuo n IEI. A oi aea a?aiy o aieueiuo, ia?aianoeo niiioaiiua ia?ieneciu AEO, noieeay iiiiii?oiay aeaeoaei/eiaay oaoeea?aeey eiaeooee?iaaeanue aeinoiaa?ii /aua — a 42,3% neo/aaa (p<0,001). Noieeay iieeii?oiay aeaeoaei/eiaay oaoeea?aeey auea eiaeooee?iaaia o 14 aieueiuo, /oi ninoaaeyao 21,8% io /enea aieueiuo n eiaeoeoeeae AEO. O 15 aieueiuo i?e i?iaaaeaiee INAEN auea eiaeooee?iaaia ianoieeay iiiiii?oiay aeaeoaei/eiaay oaoeea?aeey yoi ninoaaeyao 23,4% io /enea aieueiuo n eiaeoeoeeae AEO. Ianoieeay iieeii?oiay aeaeoaei/eiaay oaoeea?aeey auea eiaeooee?iaaia o 9 aieueiuo, /oi ninoaaeei 14,0% io /enea aieueiuo IEI n eiaeoeoeeae AEO. I?e i?iaaaeaiee i?ia?aiie?oaiie noeioeyoeee aeaeoaei/eia na?aeoea o 57 aieueiuo n iinoeioa?eoiui ea?aeeineea?icii aeaeoaei/eiaay oaoeea?aeey auea eiaeooee?iaaia 29 aieueiuo, /oi ninoaaeei 50,8% io iauaai eiee/anoaa ianeaaeiaaiiuo. A a?oiia aieueiuo n iinoeioa?eoiui ea?aeeineea?icii, o eioi?uo auee auyaeaiu niiioaiiua ia?ieneciu aeaeoaei/eiaie oaoeea?aeee, /anoioa eiaeoeoeee AEO i?e i?iaaaeaiee i?ia?aiie?oaiie noeioeyoeee aeaeoaei/eia na?aeoea auea aeinoiaa?ii auoa e ninoaaeea 94,1% (p<0,001). O 11 aieueiuo i?e i?iaaaeaiee INAEN auea eiaeooee?iaaia noieeay iiiiii?oiay aeaeoaei/eiaay oaoeea?aeey (yoi ninoaaeei 37,9% io eiee/anoaa aieueiuo 3-e a?oiiu, eee 19,3% io anao ianeaaeiaaiiuo aieueiuo n iinoeioa?eoiui ea?aeeineea?icii). O aieueiuo ni niiioaiiuie ia?ieneciaie AEO /anoioa eiaeoeoeee noieeie iiiiii?oiie aeaeoaei/eiaie oaoeea?aeee auea aeinoiaa?ii auoa e ninoaaeea 68,7% (p<0,001). O 5 aieueiuo i?e INAEN auea eiaeooee?iaaia noieeay iieeii?oiay aeaeoaei/eiaay oaoeea?aeey /oi ninoaaeyao 17,2% io /enea aieueiuo 3-e a?oiiu. O 8 aieueiuo i?e i?iaaaeaiee INAEN eiaeooee?iaaia ianoieeay iiiiii?oiay aeaeoaei/eiaay oaoeea?aeey — 27,5% io /enea aieueiuo a 3-e a?oiiu. O 5 aieueiuo i?e INAEN eiaeooee?iaaia ianoieeay iieeii?oiay aeaeoaei/eiaay oaoeea?aeey yoi ninoaaeei 17,2% io /enea aieueiuo iinoeioa?eoiui ea?aeeineea?icii n eiaeoeoeeae AEO. Anai ianeaaeiaaiui aieueiui i?iaiaeeeanue aeaooia?iay yoiea?aeeia?aoey. Auyaeaiu eeeie/aneea e aaiiaeeiaie/aneea oaeoi?u, niinianoaothuea aicieeiiaaieth yeaeo?e/aneie ianoaaeeueiinoe na?aeoea. Ooi/iaiu iieacaiey e i?iaaaeaieth i?ia?aiie?oaiie noeioeyoeee aeaeoaei/eia na?aeoea Eeth/aaua neiaa: eioa?eo ieiea?aea, i?ia?aiie?oaiay noeioeyoeey aeaeoaei/eia na?aeoea, yeaeo?e/aneay ianoaaeeueiinoue na?aeoea. Nienie oiiaieo nei?i/aiue A?I — aino?ee ?ioa?eo i?iea?aea AEOI — aino?a e?aioeoii/eiaa iaaeinoaoi?noue ?ON — ?oai?/ia oai?iaa na?oey IIOO — iano?eea iiiiii?oia oeoii/eiaa oao?ea?ae?y IIOO — iano?eea iie?ii?oia oeoii/eiaa oao?ea?ae?y I?EN — i?ney?ioa?eoiee ea?ae?ineea?ic INON — i?ia?aiiaaia noeioeyoe?y oeoii/e?a na?oey NIOO — no?eea iiiiii?oia oeoii/eiaa oao?ea?ae?y NIOO — no?eea iie?ii?oia oeoii/eiaa oao?ea?ae?y OO — oeoii/eiaa oao?ea?ae?y AOAe — aeaeo?io?c?ieia?/ia aeine?aeaeaiiy

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