Oaaea?aeueiia aaaionoai ii ia?aciaaieth
Oieueyooeineee ainoaea?noaaiiue oieaa?neoao
Aoiaieoa?iue einoeooo
Aeieeaae
Ii Aaciianiinoe aeeciaaeayoaeueiinoe
Ia oaio: «Aaa?ee ia oeie/aneeo i?aaei?eyoeyo».
Nooaeaioee ia?aiai eo?na
INO-101
?yaiaie Iaoaeuee Aaneeueaaiu
I?aiiaeaaaoaeue: Ciaieia
E?eia Aaeaioeiiaia
a. Oieueyooe
2007 a.
Aaa?ee ia oeie/aneeo i?aaei?eyoeyo.
Oeie/anee iianiua iauaeou (OII) – iauaeou ia?iaeiiai oicyenoaa,
i?iecaiaeyuea, o?aiyuea eee eniieuecothuea aaa?eeii-oeie/aneea iianiua
aauanoaa (AOIA).
A ianoiyuaa a?aiy a ia?iaeiii oicyenoaa oe?iei i?eiaiythony oeie/aneea
niaaeeiaiey, aieueoeinoai ec eioi?uo i?aaenoaaeytho iianiinoue aeey
/aeiaaea. Ec 10 iei oeie/aneeo niaaeeiaiee, i?eiaiyaiuo a
i?iiuoeaiiinoe, naeueneii oicyenoaa e auoo, aieaa 500 aunieioiene/iua e
iianiu aeey /aeiaaea.
E oeie/anee iianiui iauaeoai ioiinyo:
· I?aaei?eyoey oeie/aneie, iaooaia?a?aaaouaathuae i?iiuoeaiiinoe
· I?aaei?eyoey ieuaaie, iyniiiei/iie i?iiuoeaiiinoe, oeaaeieiiaeiaou,
i?iaeiaieuenoaaiiua aacu, eiathuea oieiaeeeueiua onoaiiaee, a eioi?uo a
ea/anoaa oeaaeiaaia eniieuecoaony aiieae
· Aiaeii/enoiua e ae?oaea nii?oaeaiey, eniieuecothuea oei?
· Neeaaeu n caianii neeueiiaeaenoaothueo oeie/aneeo aauanoa (NAessA)
I?e/eiaie aaa?ee ia i?iecaiaenoaa, eniieuecothuai oeie/aneea aauanoaa,
/aua anaai auaaao:
– ia?ooaiea i?aaee o?ainii?oe?iaee e o?aiaiey yaeiaeouo aauanoa
– ianiaethaeaiea i?aaee oaoieee aaciianiinoe
– auoiae ec no?iy aa?aaaoia, iaoaieciia, o?oaii?iaiaeia
– iaeni?aaiinoue n?aaenoa o?ainii?oe?iaee
– ?acaa?iaoecaoeey aieinoae o?aiaiey
– i?aauoaiea ii?iaoeaiuo caiania
Eaaeaeua nooee a ie?a ?aaeno?e?oaony ieiei 20 oeie/aneeo aaa?ee.
I?eia?aie iiaoo neoaeeoue:
1961a. 22 ethey a Aeca?aeeinea ec-ca ?ac?uaa oei?ii?iaiaea auea
ca?aaeaia oa??eoi?ey oeicaaiaea. 44 /aeiaaea iieo/eee io?aaeaiey
?acee/iie oyaeanoe.
1965a. 18 ethiy a Iiai-Eeiaoeeii iaoaeeo?ae/aneii eiiaeiaoa i?iecioea
ooa/ea aiieaea. 1 /aeiaae iiaea, 35 iieo/eee io?aaeaiey, iino?aaeaee
iiiaea aeeoaee ai?iaea, iaoiaeeaoeany a caeaieyo, aaoiaonao, o?aiaayo.
1983a. 15 iiya?y ia Eaia?ianeii II «I?ia?ann» iia?aaeaeaia oeenoa?ia n
60 oiiiaie oei?a. Iaeaei caiieieei oa??eoi?eth iauaaeeiaiey (5 oun. i?).
26 ?aaioieeia iiaeaee, aeanyoee iieo/eee io?aaeaiey ?acee/iie noaiaie
oyaeanoe.
A ?acoeueoaoa aaa?ee eee eaoano?io ia oeie/aneeo i?aaei?eyoeyo aicieeaao
i/aa oeie/aneiai ca?aaeaiey (IOC). A i/aaa oeie/aneiai ii?aaeaiey eee
ciia oeie/aneiai ca?aaeaiey (COC) iiaeao ieacaoueny naii i?aaei?eyoea e
i?eeaaathuay e iaio oa??eoi?ey. A niioaaonoaee n yoei auaeaeytho 4
noaiaie iianiinoe oeie/aneeo i?aaei?eyoee:
I. A ciio aiciiaeiiai ca?aaeaiey iiiaaeatho aieaa 75000 /aeiaae
II. A ciio aiciiaeiiai ca?aaeaiey iiiaaeatho 40000 – 75000 /aeiaae
III. A ciio aiciiaeiiai ca?aaeaiey iiiaaeatho iaiaa 40000 /aeiaae
IV. Ciia aiciiaeiiai oeie/aneiai ca?aaeaiey ia auoiaeeo ca i?aaeaeu
i?aaei?eyoey.
Iineaaenoaey aaa?ee ia oeie/aneeo i?aaei?eyoeyo ii?aaeaeythony
noaiaiueth iianiinoe oeie/aneeo aauanoa e eo oiene/iinoueth.
Ii iieacaoaeyi oiene/iinoe e iianiinoe oeie/aneea aauanoaa aeaeyo ia 4
eeanna:
1. /?acau/aeii iianiua (LC50 iaiaa 0,5 a/i3)1
2. auniei iianiua (LC50 aei 5 a/i3)1
3. oia?aiii iianiua (LC50 aei 50 a/i3)1
4. iaei iianiua (LC50 aieaa 50 a/i3)1
LC50 – eiioeaio?aoeey, aucuaathuay aeaaeue 50% aeeaioiuo,
iiaeaa?aioouo aicaeaenoaeth.
Ii oa?aeoa?o aicaeaenoaey ia i?aaieci /aeiaaea aaa?eeii-oeie/aneea
iianiua aauanoaa eee neeueiiaeaenoaothuea oeie/aneea aauanoaa aeaeyony
ia neaaeothuea a?oiiu:
1. aauanoaa oaeooathuaai aicaeaenoaey
A) n au?aaeaiiui i?eaeeaathuei yooaeoii (oei?)
A) ni neaai i?eaeeaathuei yooaeoii (oinaai)
2. aauanoaa iaua yaeiaeoiai aeaenoaey (neieeueiay eeneioa, oeeaieaeu,
oaa?iue aac)
3. aauanoaa oaeooathuaai e iauayaeiaeoiai aeaenoaey
A) n au?aaeaiiui i?eaeeaathuei yooaeoii (acioiay eeneioa,
niaaeeiaiey ooi?a)
A) ni neaai i?eaeeaathuei yooaeoii (na?iaiaei?iae, ieneaeu acioa)
4. iae?io?iiiua yaeu (oinoi?i?aaie/aneea niaaeeiaiey, na?ioaea?iae)
5. iae?io?iiiiai e oaeooathuaai aeaenoaey (aiieae, aeae?acei)
6. iaoaaiee/aneea yaeu (aeeoei?yoai, ieneae yoeeaia)
7. aauanoaa, eca?auathuea iaiai aauanoa (aeeienei, aaicioo?aeu)
E?iia oiai, ana AIOA aeaeyony ia auno?iaeaenoaothuea e
iaaeeaiiiaeaenoaothuea. I?e ii?aaeaiee ia?auie ea?oeia io?aaeaiey
?acaeaaaony auno?i, a ai aoi?ii neo/aa aei i?iyaeaiey ea?oeiu io?aaeaiey
i?ioiaeeo ianeieueei /ania, oae iacuaaaiue eaoaioiue ia?eiae (ne?uoue).
Aiciiaeiinoue aieaa eee iaiaa i?iaeieaeeoaeueiiai ca?aaeaiey ianoiinoe
caaeneo io noieeinoe oeie/aneiai aauanoaa. Noieeinoue aea, a naith
i/a?aaeue, caaeneo io oaiia?aoo?u eeiaiey aauanoaa. E ianoieeei
ioiinyony AIOA n oaiia?aoo?ie eeiaiey aei 130°C, a e noieeei – auoa
130°C. Ianoieeea ca?aaeatho ianoiinoue ca ieioou eee aeanyoee ieioo,
noieeea – io ianeieueeeo /ania aei ianeieueeeo ianyoeaa.
N iiceoeee i?iaeieaeeoaeueiinoe ii?aaeathuaai aeaenoaey e a?aiaie
ianooieaiey ii?aaeathuaai yooaeoa AIOA aeaeyony ia 4 a?oiiu:
1. ianoieeea n auno?iianooiathuei aeaenoaeai – neieeueiay eeneioa,
aiieae, ieneae oaea?iaea.
2. ianoieeea caiaaeeaiiiai aeaenoaey – oinaai, acioiay eeneioa.
3. noieeea n auno?iianooiathuei aeaenoaeai – oinoi?aaie/aneea
niaaeeiaiey, aieeei.
4. noieeea caiaaeeaiiiai aeaenoaey – na?iay eeneioa, oao?ayoeenaeiaoe.
Oa??eoi?ey, iiaeaa?aoayny ca?aaeaieth AIOA, ia eioi?ie iiaoo aicieeiooue
ianniaua ii?aaeaiey ethaeae, iacuaaaony i/aaii oeie/aneiai ii?aaeaiey
(IOI).
Ia ca?aaeaiiie oa??eoi?ee aauanoaa iiaoo iaoiaeeoueny a
eaiaeueii-aeeaeeii, ia?iia?aciii, ay?icieueiii e aaciia?aciii ninoiyiee.
I?e aua?ina a aoiinoa?o ia?iia?aciuo e aaciia?aciuo oeie/aneeo
niaaeeiaiee oi?ie?oaony ia?ae/iia ca?aaeaiiia iaeaei, eioi?ia a
caaeneiinoe io ieioiinoe aaca, ia?a aoaeao a oie eee eiie noaiaie
?annaeaaoueny a aoiinoa?a. Aacu n aunieei iieacaoaeai ieioiinoe (aieueoa
1) aoaeoo noaeeoueny ii caiea, a n ieioiinoueth iaiueoa 1 – auno?i
?annaeaaoueny a aunoeo neiyo aoiinoa?u.
A eiia/iii n/aoa, ciia oeie/aneiai ca?aaeaiey AIOA aeeth/aao 2
oa??eoi?ee: iiaeaa?aeaiiay iaiin?aaenoaaiiiio aicaeaenoaeth e oa, iaae
eioi?ie ?ani?ino?aieeinue ca?aaeaiiia iaeaei.
Oeacaiiua e iiiaea ae?oaea oaeoi?u, oa?aeoa?ecothuea ciio oeie/aneiai
ca?aaeaiey, iaiaoiaeeii o/eouaaoue i?e ieaie?iaaiee ?aaio ii
eeeaeaeaoeee iineaaenoaee aaa?ee ia oeie/anee iianiuo iauaeoao.
Iauea o?aaiaaiey e i?aaiecaoeee e i?iaaaeaieth aaa?eeii-nianaoaeueiuo
?aaio ia oeie/anee iianiuo i?aaei?eyoeyo onoaiaaeeaaao Ainoaea?noaaiiue
noaiaea?o ?O AINO ? 22.8-05-99.
A niioaaonoaee ni noaiaea?oii onoaiaaeeaaaony:
– aaa?eeii-nianaoaeueiua ?aaiou aeieaeiu ia/eiaoueny iaiaaeeaiii iinea
i?eiyoey ?aoaiey i i?iaaaeaiee iaioeiaeiuo ?aaio; aeieaeiu i?iaiaeeoueny
n eniieueciaaieai n?aaenoa eiaeeaeaeoaeueiie caueou i?aaiia aeuoaiey e
eiaee, niioaaonoaothueo oeie/aneie ianoaiiaea; aeieaeiu i?iaiaeeoueny
iai?a?uaii aeiai e ii/ueth a ethaoth iiaiaeo n niaethaeaieai
niioaaonoaothuaai ianoaiiaea ?aaeeia aeayoaeueiinoe nianaoaeae aei
iieiiai caaa?oaiey ?aaio.
– I?aaeaa?eoaeueii i?iaiaeeony ?acaaaeea aaa?eeiiai iauaeoa e ciiu
ca?aaeaiey, ianooaaia e a?aieoe ciiu ca?aaeaiey, ooi/iaiea ninoiyiey
aaa?eeiiai iauaeoa, ii?aaeaeaiea oeia /?acau/aeiie neooaoeee.
– Aaa?eeii-nianaoaeueiua ?aaiou
– Inouanoaeaiea ieacaiey iaaeeoeeineie iiiiue ii?aaeaiiui, eo
yaaeoaoeey.
– Eieaeecaoeey, iiaeaaeaiea, nieaeaiea aei ieieiaeueii aiciiaeiiai
o?iaiy aicaeaenoaey ii?aaeathueo oaeoi?ia.
Aeaaiua caaea/e oeie/aneie ?acaaaeee:
ue Ooi/iaiea iaee/ey e eiioeaio?aoeee io?aaeythueo aauanoa ia iauaeoa
?aaio, a?aieoe e aeeiaieee eciaiaiey oeie/aneiai ca?aaeaiey.
ue Iieo/aiea iaiaoiaeeiuo aeaiiuo aeey i?aaiecaoeee
aaa?eeii-nianaoaeueiuo ?aaio e ia? aaciianiinoe ianaeaiey.
ue Iinoiyiiia iaaethaeaiea ca eciaiaieai oeie/aneie ianoaiiaee a ciia
/?acau/aeiie neooaoeee, i?aaeoi?aaeaeaiea ia eciaiaiee ianoaiiaee.
Oeie/aneay ?acaaaeea aaaeaony iooai iniio?a, n iiiiuueth niaoeeaeueiuo
i?eai?ia.
Iaeiia?aiaiii a ciia ca?aaeaiey aaaeoony iieneiai-nianaoaeueiua ?aaiou.
Iiene i?iaiaeeony iooai aecoaeueiiai ianeaaeiaaiey oa??eoi?ee, caeaiee,
nii?oaeaiee, oeaoia e o.ae., a oaeaea ii?ina i/aaeaeoeaa e n iiiiuueth
niaoeeaeueiuo i?eai?ia a neo/aa ?ac?ooaiee e caaaeia.
Nianaoaeueiua ?aaiou i?iaiaeyony n iaycaoaeueiui i?eiaiaieai n?aaenoa
eiaeeaeaeoaeueiie caueou.
I?e nianaiee iino?aaeaaoeo ia oeie/aneii i?aaei?eyoee o/eouaaaony
oa?aeoa?, oyaeanoue ii?aaeaiey, ianoiiaoiaeaeaiea iino?aaeaaoaai.
I?e yoii inouanoaeythony neaaeothuea ia?ii?eyoey:
1. aeaaeiee?iaaiea iino?aaeaaoaai, iaoiaeyuaainy iiae caaaeaie, a oaeaea
a aeiee?iaaiiuo iiiauaieyo
2. yeno?aiiia i?ae?auaiea aeaenoaey iianiuo oeie/aneeo aauanoa ia
i?aaieci iooai i?eiaiaiey n?aaenoa eiaeeaeaeoaeueiie caueou.
3. ieacaiea ia?aie iaaeeoeeineie iiiiue.
Ia?aay iaaeeoeeineay iiiiuue:
1. auno?ia i?ae?auaiea aicaeaenoaey iianiuo oeie/aneeo aauanoa ia
i?aaieci iooai oaeaeaiey eaiaeue aauanoaa n ioe?uouo iiaa?oiinoae oaea,
i?iiuaaiey aeac e neecenouo.
2. Ainnoaiiaeaiea ooieoeeiie?iaaiey aaaeiuo nenoai i?aaiia iooai
neaaeothueo ia?ii?eyoee: eneonnoaaiiay aaioeeyoeey eaaeeo, iai?yiie
iannaae na?aeoea, i?i/euaiea aeuoaoaeueiuo iooae.
3. Iaeiaeeoue iiaycee ia ?aiu e eiiiaeeeciaaoue iia?aaeaeaiiua
eiia/iinoe.
4. Yaaeoe?iaaoue a iaaeeoeeineee ioieo.
Eieaeecaoeey i/aaa:
1. i?ae?auaiea aua?inia IOA
2. iinoaiiaea aeeaeeinoiuo caaan (aiaeyiuo eee iaeo?aeecothueo
?anoai?ia) a iai?aaeaiee aeaeaeaiey iaeaea IOA
3. nicaeaiea ainoiaeyueo oaieiauo iioieia a iai?aaeaiee aeaeaeaiey
iaeaea IOA
4. ?annaeaaiea e niauaiea iaeaea IOA aaciaicaeooiui iioieii
5. ia?aie/aiea ieiuaaee i?ieeaa e eioaineaiinoe enia?aiey IOA
6. nai? (ioea/ea) IOA a ?aca?aiua aieinoe
7. ioeaaeaeaiea i?ieeaa IOA oaa?aeie oaeaeeneioie eee iaeo?aeecothueie
aauanoaaie
8. canuiea i?ieeaa nuio/eie aauanoaaie
9. caaouaiea i?ieeaa niaoeeaeueiuie ninoaaaie n iineaaeothuae
iaeo?aeecaoeeae e auaicii
10. auaeeaaiea i?ieeaa.
Eeoa?aoo?a:
Aaciianiinoue aeeciaaeayoaeueiinoe / O.I. Oaai, I.A. Oaai. –
?inoia-ia-Aeiio: Oaieen, 2001.
*aeiaae a yeno?aiaeueiie neooaoeee / A.A. Ainothoei. – I.:
A?iaaea-i?ann, 2001.
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