6

OA?E?ANUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

IIEssEIA Aiaoie?e ?aaai?eiae/

OAeE 616.13-004.6:577.115:577.352.24-073.53

CIA*AIIss ??AeEIIIE?ENOAE?*IIAI (IACIII?OIIAI)

NOAIO E?I?Ae?A O IAOIAAIAC? AOA?INEEA?ICO

OA Ae?AAIINOEOe? AOA?IAAIIEO AeENE?I?AeAI?E

(ee?i?ei-aenia?eiaioaeueia aeine?aeaeaiiy)

14.01.11 — ea?ae?ieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Oa?e?a — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioo aeeiiaii a Iaeanueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? IIC
Oe?a?ie.

Iaoeiaee eiinoeueoaio aeieoi? iaaee/ieo iaoe, i?ioani? TH?eia
Aeaaeeneaa Ieoaeeiae/, Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao,
caa?aeoaa/ eaoaae?e aini?oaeueii? oa?ai??

Io?oe?ei? iiiiaioe aeaaeai?e AII Oe?a?ie, aeieoi? iaaee/ieo iaoe,
i?ioani?, Aecye Aai?a?e A?eoi?iae/, Aei?i?iiao?ianueea aea?aeaaia
iaaee/ia aeaaeai?y, ?aeoi? aeaaeai??, caa?aeoaa/ eaoaae?e aini?oaeueii?
oa?ai?? ? 2

— aeieoi? iaaee/ieo iaoe, i?ioani? Eiaaeue Na?a?e Ieeieaeiae/, ?inoeooo
oa?ai?? AII Oe?a?ie, i. Oa?e?a, caa?aeoaa/ a?aeae?eo a?oa??aeueii?
a?ia?oii??

— aeieoi? iaaee/ieo iaoe, i?ioani? I?eiiia Aaaeei Aieiaeeie?iae/,
Oa?e?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe, caa?aeoaa/
eaoaae?e oaeaeei? oa iaa?aeeeaaeii? aeiiiiiae

I?ia?aeia i?aai?caoe?y ?inoeooo ea?ae?ieia?? ?i. aeaae.
 I.Ae. No?aaeanea AII Oe?a?ie, a?aeae?e aoa?ineea?ico oa ?oai?/ii?
oai?iae na?oey, i. Ee?a

Caoeno a?aeaoaeaoueny 28 aeiaoiy 1999 ?. i 1230 aiae. ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.600.04 i?e Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca aae?anith: 310022, i. Oa?e?a,
i?. Eai?ia, 4.

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ca aae?anith: 310022, i. Oa?e?a,
i?. Eai?ia, 4.

Aaoi?aoa?ao ?ic?neaiee 27 aa?aniy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio E.?. Ia/a?aiei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Na?oeaai-noaeeii? caoai?thaaiiy, ui coiiaeai?
aoa?ineea?ioe/iei o?aaeaiiyi, caeiathoue /?eueia i?noea na?aae i?e/ei
?iaae?aeecaoe?? oa nia?oiino? ianaeaiiy a on?o aac aeiyoeo ?icaeiooeo
e?a?iao na?oo ? ? iaeaaaeeea?oith nioe?aeueiith oa iaaee/iith i?iaeaiith
no/aniino?. [AIC, 1998].

Na?aae /eneaiieo oai??e aoa?ineea?ico oieanoa?eiiaa eiioeaioe?y, o
no/ani?e ?ioa?i?aoaoe?? — e?iii?ioa?aeia, caeeoa?oueny aeii?ioth/ith.
Iaeiae, ia caaaeath/e ia aeinyaioo? oni?oe o aea/ai? aoa?iaaiaco,
iaoai?cie i?e/eiii-iane?aeeiaiai ca’yceo a?ia?oieanoa?eiai?? oa
e?i?aeii? ?io?eueo?aoe?? ?ioeie a?oa??e, c iaeiiai aieo, oa i?aeneeaii?
ee?oeiii? i?ie?oa?aoe??, ui ? aieiaiith eaieith iaoiaaiaco
aoa?ineea?ico, c ?ioiai — caeeoathoueny iac’yniaaieie [?aiei A.N.,
Nie?iia A.I., 1989; Gertz S.D., Kurgan A., 1988].

O?iiaioeeoa?iiio aaiinoaco iaaeathoue aaaeeeaiai cia/aiiy o iaoiaaiac?
?ON [Iaeay E.O. e niaao., 1977, Ee?e/oe A.O., Oaa?oe TH.A., 1998].
Ia?aeiiee iaoai?ci aca?iiae?? ieanoeiie e?ia? cia/iith i??ith
caaacia/o?oueny aeaeo?e/ieie aeanoeainoyie oeeo ee?oei [Ia?einyi ?.A. e
niaao., 1985]. Aaee/eia aeaeo?e/iiai ca?yaeo ee?oeiieo aeaiaio?a
aecia/a?oueny ia o?eueee eiioeaio?aoe??th ia ciai?oi?e iiaa?oi?
ieaciaoe/ii? iaia?aie ?ii?a, aea oaeiae ??aeeiiie?enoae?/ieie
aeanoeainoyie e?i?ae?a, ui aoiaeyoue aei ?? neeaaeo [Aa?aniaa E.A.,
Aeeiia E.I., 1983].

A?aeiii, ui iicaee?oeii? e?i?aee o?aaeaii? aoa?ineea?icii a?oa??aeueii?
no?iee ooai?ththoue ??aeeiiie?enoae?/io oaco (iacioaco) [Ieioe ?.A.
Eiiiiaiei A.A. 1981; Adams C.W.M., Bayliss O.B., 1975]. Neeaaei?
e?i?aei? ??aeeiiie?enoae?/i? no?oeoo?e ca iaaieo oiia caeaoi? aeyaeyoe
naaiaoi- oa i’?ciaeaeo?e/i? aoaeoe, a oaeiae iiey?ecoaaoeny i?ae ae??th
ciai?oiueiai aeaeo?e/iiai iiey [Aio?a C.TH. e niaao., 1989].
Aaciina?aaei? aeyaeaiiy oaeeo aeanoeainoae e?i?aeieo ??aeeeo e?enoae?a,
ye? oi?iothoueny a a?oa??aeuei?e no?ioe?, iiaei a i?eaanoe aei ooi/iaiiy
aai iaa?oue ia?ainieneaiiy ?ie? e?i?ae?a a aoa?iaaiac? ?, oaeei /eiii,
neoaeeoe iaa?oiooaaiiyi aeey ?ic?iaee iiaeo iaoiae?a ae?aaiinoeee
aoa?iaaiieo aeene?i?aeai?e, a a ia?niaeoea? — cania?a i?io?eaeoeee oa
e?eoaaiiy aoa?ineea?ico.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?th
aeeiiaii a Iaeanueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? a ?aieao
caoaa?aeaeaii? IIC Oe?a?ie IAe? eaoaae?e aini?oaeueii? oa?ai?? «Aea/eoe
?ieue iacioaciiai noaio e?i?ae?a a aoa?iaaiac? oa ?ic?iaeoe ia iniia?
io?eiaieo aeaieo iaoiae ae?aaiinoeee oa noaie iaaeeeaiaioicii? ei?aeoe??
aoa?iaaiieo aeene?i?aeai?e» (iaoeiaee ea??aiee — i?io. TH?eia A.I.,
a?aeiia?aeaeueiee aeeiiaaaoeue — aeioe. Iieyeia A.?., ?
aea?ae?a?no?aoe?? UA 01001976 P).

Iaoa ?iaioe — c’ynoaaiiy ?ie? ??aeeie?enoae?/ieo e?i?ae?a a aoa?iaaiac?
? ?ic?iaea ia iniia? io?eiaieo aeaieo niiniao ae?aaiinoeee aoa?iaaiieo
aeene?i?aeai?e.

A?aeiia?aeii aei iinoaaeaii? iaoe aei caaea/ ?iaioe aoiaeeei:

a) aeine?aeaeaiiy iioe/ieo ? aeaeo?e/ieo aeanoeainoae e?i?aeieo
aeeth/aiue ?ioeiaeueii? iaieiiee a?oa??e oai?eo ia aoa?ineea?ic;

a) aeine?aeaeaiiy ii?ooaiue e?iii?ioa?aeiiai o?ainii?oo i?ae ieaciith
e?ia? e o?aaeaiith aoa?ineea?icii a?oa??aeueiith no?ieith o oai?eo ye
oiiae oi?ioaaiiy e?i?aeaie ?ioeie ??aeeie?enoae?/ii? oace;

a) ioe?iea cia/eiino? /anoeiai? o/ano? aieiaieo e?i?ae?a (OE, a?eueiee
ON, a?euei? AEE, OA, anoa?eo?eiaaiee ON oa caaaeueiee ON) o oi?ioaaii?
aeaeo?e/ieo aeanoeainoae noia?ieo e?i?ae?a a?oa??aeueii? no?iee oai?eo
ia aoa?ineea?ic;

a) aeine?aeaeaiiy nenoaie IIE o ieaci? e?ia? e a?oa??aeuei?e no?ioe?
oai?eo ia aoa?ineea?ic ? ioe?iea cia/eiino? ?? aeoeaiino? o oi?ioaaii?
aeaeo?e/ieo aeanoeainoae e?i?ae?a a?oa??aeueii? no?iee oai?eo ia
aoa?ineea?ic;

ae) aeine?aeaeaiiy aieeao ??aeeie?enoae?/ii? oace ia oa?aeoa? ?inoo ?
i?ie?oa?aoeaio aeoeai?noue ee?oei o eoeueoo?? oa in vivo a aenia?eiaio?
ia oaa?eiao;

a) aeine?aeaeaiiy ?ie? ??aeeie?enoae?/iiai noaio e?i?ae?a a aa?aaaoe??
o?iiaioeeo?a;

ae) ?ic?iaea niiniao ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. Aia?oa anoaiiaeaii, ui
iicaee?oeii? ??aeeie?enoae?/i? e?i?aei? aeeth/aiiy ?ioeiaeueii? iaieiiee
a?oa??e, o?aaeaieo aoa?ineea?icii, i?e oaiia?aoo?? aioo??oiueiai
na?aaeiaeua i?aai?cio (37 — 38,5 °N) iathoue naaiaoi-, aioenaaiaoi- ?,
ioaea, i’?ciaeaeo?e/i? aeanoeaino?.

Aia?oa anoaiiaeaii, ui anioe?eiaaia c o?ainoi?iaoe??th EIi o OA
?oeioaaiiy i?ienoeo ee?oei ? aeeea e?i?ae?a, ui i?noyoueny a ieo, o
iicaee?oeiiee i?ino?? ? ?acoeueoaoii oaciaiai ia?aoiaeo oeeo e?i?ae?a c
aii?oiiai o ??aeeie?enoae?/iee noai.

Aia?oa anoaiiaeaii, ui ia noaae?? EIi a ?ioeio i?iieeathoue EIA ? EAA.
Ia?o? caaacia/othoue aeinoaaeo ON ? i?aeaeathoueny iaiai?ioiiio
eaoaaie?cio, ae?oa? aeiinyoue ON o ieacio e?ia?. Ia noaae?? OA o?ainii?o
EIA a a?oa??aeueio no?ieo ciaioo?oueny, a EAA, ui i?iieeathoue aei ia?,
eaoaaie?cothoue. I?e aoa?iiaoic? i?iieeiaiiy a ?ioeio EI on?o eean?a
cieaeaia. Naeaeoeai?noue ? ??cia ?ioaineai?noue i?yiiai e cai?ioiiai
o?ainii?oo EI i?ae e?ia’th e ie?aieie ae?eyieaie a?oa??aeueii? no?iee
noai?th? oiiae aeey eieaeueiiai ca?eueoaiiy a inoaii?o eiioeaio?aoe??
anoa?eo?eiaaiiai ON ? oaciaiai ia?aoiaeo e?i?aeieo eiiiiiaio?a c
aii?oiiai o ??aeeie?enoae?/iee noai.

Aia?oa anoaiiaeaii, ui na?aae e?i?ae?a (OE, a?eueiee ON, a?euei? AEE,
OA, anoa?eo?eiaaiee ON oa caaaeueiee ON) iaea?eueoith i??ith aieeaathoue
ia oi?ioaaiiy aeaeo?e/ieo aeanoeainoae noia?ieo ??aeeie?enoae?/ieo
e?i?ae?a aoa?ineea?ioe/ieo aeaiaio?a — OA oa caaaeueiee ON.

Aia?oa anoaiiaeaii, ui ia oi?ioaaiiy aeaeo?e/ieo aeanoeainoae
??aeeie?enoae?/ieo e?i?ae?a aoa?ineea?ioe/ieo aeaiaio?a aieeaa?
aeoeai?noue ia?aeeniiai ieeneaiiy.

Aia?oa aenia?eiaioaeueii anoaiiaeaii, ui iicaee?oeiii ?icoaoiaai? ??aee?
e?enoaee aeoeaothoue i?ie?oa?aoe?th ioi/oth/eo ee?oeiieo aeaiaio?a.
Oaeei /eiii, iicaee?oeii? ??aeeie?enoae?/i? e?i?aei? ooai?aiiy
a?oa??aeueii? no?iee caeaoi? ?i?oe?thaaoe ii?oiaaiac aoa?ineea?ioe/ii?
aeyoee, ui i?aeoaa?aeaeo? ?ieue ON a aoa?iaaiac?, cia/ei?noue
oieanoa?eiiai? oai??? aoa?ineea?ico ? aeicaiey? ?icaeiooe ?? o
??aeeie?enoae?/io eiioeaioe?th. I?aeaeuaiiy i?ie?oa?aoeaii? aeoeaiino?
ee?oei i?e eiioaeo? c ??aeeie?enoae?/ieie no?oeoo?aie iaoiiaeaii
caeaoi?noth inoaii?o iaeiie/oaaoe aeaeo?e/iee ca?yae.

?ic?iaeaia ??aeeie?enoae?/ia eiioeaioe?y aoa?iaaiaco eiinie?aeo?
oieanoa?eiiao oai??th c noaeeiiith ? iineoue oi?aa?naeueiee oa?aeoa?. Ia
iniia? oyaeaiue i?i ?ieue o iaoiaaiac? aoa?ineea?ico aeaeo?e/ieo
e?i?aeieo ??aeeeo e?enoae?a, ye? ciaoiaeyoueny o neeaae? ?ioeiaeueii?
iaieiiee a?oa??aeueii? no?iee, cai?iiiiiaai?:

§ a?iioaca, ui aeicaiey? iiynieoe ia?aaaaeio eieae?caoe?th
aoa?ineea?ioe/ieo o?aaeaiue o i?ieneiaeueieo a?aeae?eao, i?noeyo aeaei?a
? a?oo?eaoe?e a?oa??aeueiiai ?onea;

§ a?iioaca, ui ?ioa?i?aoo? iaoai?ci aoa?iaaiii? ae?? a?oa??aeueii?
a?ia?oaic??;

§ a?iioaca eaeueoeeioaaiiy a?oa??e i?e aoa?ineea?ic?;

§ a?iioaca, ui noino?oueny ?ie? IIE o iaoiaaiac? aoa?ineea?ico;

§ a?iioaca, ui iiynith? cia/aiiy AEE o iaoiaaiac? aoa?ineea?ico ?
iaoai?ci aoa?iaaiii? oa i?ioeaoa?ineea?ioe/ii? ae?? iane/aieo ?
aenieiiaiane/aieo AEE a?aeiia?aeii;

§ a?iioaca, ui noino?oueny ?ie? EAA a aoa?iaaiac?.

Aia?oa anoaiiaeaii, ui i?e aeene?i?aeai?yo aoa?iaaiiiai oa?aeoa?o
aa?aaaoe?eia caeaoi?noue e?ia’yieo ieanoeiie (I oaca aa?aaaoe??)
ca?eueoo?oueny o ca’yceo c? ci?iith ??aeeie?enoae?/ieo aeanoeainoae
ieaciaoe/ieo iaia?ai oeeo ee?oei.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. 1. Anoaiiaeaiiy ?ai?oa
iaa?aeiieo iaoai?ci?a aoa?iaaiaco a?aee?eaa? iiaeeea?noue ?ic?iaee iiaeo
iaoiae?a i?io?eaeoeee ? e?eoaaiiy caoai?thaaiue, iaoiiaeaieo
aoa?ineea?icii.

?acoeueoaoe oai?aoe/ieo ?ic?iaie aeena?oaoe?? aeei?enoai? o iaa/aeueiiio
i?ioean? o oaeeo caeeaaeao:

§ eaoaae?a aini?oaeueii? oa?ai?? Iaeanueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo ;

§ eaoaae?a iaoieia?/ii? o?c?ieia?? Iaeanueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo;

§ eaoaae?a i?iiaaeaaoeee aioo??oi?o oai?ia ? 1 Iaoe?iiaeueiiai
iaaee/iiai oi?aa?neoaoo;

§ eaoaae?a oa?ai?? ? 1 Ee?anueei? iaaee/ii? aeaaeai?? i?neyaeeieiiii?
ina?oe.

2. «Niin?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e” (iaoaio Oe?a?ie
? 19490 A; ni?aaao. – TH?eia A.I., Oaae/oe I.I., ?oaeaiei ?.I.)
aeei?enoaiee o oaeeo e?eoaaeueieo caeeaaeao:

§ 411 ie?oaeiee a?enueeiaee aini?oaeue;

§ ee?i?/ia e?ea?iy ? 2 i. Iaeane;

§ ee?i?/ia e?ea?iy ? 10 i. Iaeane.

?ic?iaeaiee «Niin?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e» ii??aiyii c
caaaeueii i?eeiyoeie e?i?aeieia?/ieie iieacieeaie ia? i?aeaeuaio
/ooeea?noue. I?e ?aae?caoe?? niiniao /enei cae?enithaaieo iia?aoe?e
iaiaaeaii, aeo?aoe /ano iaaaeee?, ui ?iaeoue iiaeeeaei eiai aeei?enoaiiy
aeey aeni?an-ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e ia o?eueee a
ee?i?/i?e i?aeoeoe?, aea e i?e ianiaeo ai?aeai?ieia?/ieo ianoaaeaiiyo
ianaeaiiy.

Iniaenoee aianie caeiaoaa/a. O ?iaio? iaae aeaea?aeaie ?ioi?iaoe?? c
iaeyaeo e?oa?aoo?e iaaeaia aeiiiiiaa aeioeaioii eaoaae?e aini?oaeueii?
oa?ai?? Iaeanueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo
I?ieiiiaith O.I. Aeania iaeyae, aiae?c e?oa?aoo?ieo aeaieo,
oi?ioethaaiiy iaae??oaieo caaea/ ii i?iaeai? cae?eniai? caeiaoaa/ai
naiino?eii.

Aeine?aeaeaiiy iioe/ieo aeanoeainoae e?i?ae?a a?oa??aeueii? no?iee
oai?eo ia aoa?ineea?ic ? ?ic?iaea iaoa??ae?a, ui noinothoueny oaciaiai
noaio e?i?ae?a oa i?ienoeo ee?oei, cae?eniai? caeiaoaa/ai naiino?eii.

Aeine?aeaeaiiy aeaeo?e/ieo aeanoeainoae e?i?ae?a a?oa??aeueii? no?iee
oai?eo ia aoa?ineea?ic i?iaaaeaii a ?aieao ni?eueii? ?iaioe c aeioeaioii
eaoaae?e aenia?eiaioaeueii? o?ceee Iaeanueeiai aea?aeaaiiai oi?aa?neoaoo
?i. ?.?. Ia/ieeiaa I.I. Oaae/oeii oa ea?iaaieie iei ani??aioaie ?
nooaeaioaie Aa?iyeii ?.I., ?oaeaiei ?.I., Oaa/aiei E.Ae.,
Aia?inetheii O.A. oa Oaae/oeii I.I. Ii oeueiio ?icae?eo ?iaioe iniaenoi
caeiaoaa/ai iaa?oioiaaii iaoo ? neeaaeaii ieai aeine?aeaeaiue,
cae?eniaii ii??aiyiiy io?eiaieo aeaieo c aeaieie e?oa?aoo?e, aeaia
?ioa?i?aoaoe?y iaoio?c?ieia?/ii? noo? aeine?aeaeoaaieo i?ioean?a,
noi?ioeueiaai? aeniiaee.

Iaoeia? ?ic?iaee, i?enay/ai? ?ie? ii?ooaiue e?iii?ioa?aeiiai o?ainii?oo
? nenoaie IIE o oi?ioaaii? e?i?aeaie a?oa??aeueii? no?iee oai?eo ia
aoa?ineea?ic ??aeeie?enoae?/ii? oace aeeiiai? caeiaoaa/ai naiino?eii.

Iaoaiaoe/ia iiaeaethaaiiy e?enoaeio?i?/ieo aeanoeainoae e?i?ae?a
a?oa??aeueii? no?iee oai?eo ia aoa?ineea?ic aeeiiai? ?acii c aeioeaioii
eaoaae?e aenia?eiaioaeueii? o?ceee Iaeanueeiai aea?aeaaiiai oi?aa?neoaoo
?i. ?.?. Ia/ieeiaa Oaae/oeii I.I. oa ani??aioii eaoaae?e ano?iiii??
oeueiai oi?aa?neoaoo Oaeoiii E.N. Ii oeueiio ?icae?eo ?iaioe iniaenoi
caeiaoaa/ai iaa?oioiaaia iaoa aeine?aeaeaiiy, cae?eniaii ii??aiyiiy
io?eiaieo aeaieo c aeaieie e?oa?aoo?e, aeaia ?ioa?i?aoaoe?y o?ce/ii?
noo? aeine?aeaeoaaieo i?ioean?a, noi?ioeueiaai? aeniiaee.

Aenia?eiaioaeuei? aeine?aeaeaiiy ia eoeueoo?ao ee?oei ? oaa?ei, a oaeiae
iaoeia? ?ic?iaee, i?enay/ai? c’ynoaaiith ?ie? ??aeeie?enoae?/ieo
e?i?ae?a o ii?oiaaiac? aoa?ineea?ioe/ii? aeyoee, aeeiiai? caeiaoaa/ai
naiino?eii.

Eiiiiceoe?? ?a/iaei c naaiaoiaeaeo?e/ieie aeanoeainoyie i?eaioiaeaii ?
iaaeaii aeey ?iaioe aieiaiei iaoeiaei ni?a?ia?oieeii eaai?aoi??? ??aeeeo
e?enoae?a ?inoeoooo e?enoaeio?ceee ?AI Aa?aniaaei E.I. (Iineaa).

?iaioa c eoeueoo?aie ee?oei, o oiio /ene? c canoinoaaiiyi ?aae?ieia?/ieo
iaoiae?a, eiinoeueoiaaia ea??aieeii eaai?aoi??? oa?iaeioeeoie?iaoeee
Iieieia?/iiai iaoeiaiai oeaio?o ?AII i?ioani?ii Aeia?ei?iei ss.A.
(Iineaa).

Aeine?aeaeaiiy aa?aaaoe?eieo aeanoeainoae o?iiaioeeo?a ? iaoeia?
?ic?iaee, i?enay/ai? aea/aiith iaoai?ci?a aa?aaaoe?? oeeo ee?oei i?e
aeene?i?aeai?yo o oai?eo ia ?ON, aeeiiai? caeiaoaa/ai naiino?eii.
I?ea?iaeueiee niin?a aecia/aiiy aa?aaaoe?eii? caeaoiino? o?iiaioeeo?a
?ic?iaeaii ?acii c anenoaioii eaoaae?e aini?oaeueii? oa?ai?? Iaeanueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo *a?iyeii A.A.

Niin?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e ?ic?iaeaii ?acii ?c
caa?aeoaa/ai eaoaae?e aini?oaeueii? oa?ai?? Iaeanueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo i?ioani?ii TH?eiaei A.I., aeioeaioii eaoaae?e
aenia?eiaioaeueii? o?ceee Iaeanueeiai aea?aeaaiiai oi?aa?neoaoo
?i. ?.?. Ia/ieeiaa Oaae/oeii I.I. ? ea?iaaiei iei ani??aioii
?oaeaiei ?.I.

Aeiiea?ia?ao?y aeeiiaia iacaeaaeiei aeine?aeieeii — aeioeaioii eaoaae?e
i?iiaaeaaoeee aioo??oi?o oai?ia. Iaeanueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo Eieii?eoeai N.I. Ii oeueiio ?icae?eo ?iaioe iniaenoi
caeiaoaa/ai iaa?oioiaaii iaoo ? neeaaeaii ieai aeine?aeaeaiue,
cae?eniaii ?ic?aooiee, ui iaa?oioiaothoue niin?a, i?iaaaeaii ii??aiyiiy
io?eiaieo aeaieo c aeaieie e?oa?aoo?e, noi?ioeueiaaii aeniiaee.

On? ee?i?/i? aeine?aeaeaiiy (iieooaaiiy e iaeyae oai?eo, ?ioa?i?aoaoe?y
aeaeo?iea?ae?ia?ai ? eaai?aoi?ieo aeaieo), ia?iaea ia?aeiiiai iaoa??aeo
oa iaoaiaoe/ia ia?iaea caaaeaieo aeaieo aeeiiai? caeiaoaa/ai naiino?eii.

Iaoa, caaea/?, on? aeniiaee, caaaeueia eiioeaioe?y aeieoi?nueei?
aeena?oaoe??, a oaeiae ?acoeueoaoe ? ?oi? iaaiai?aiiy noi?ioeueiaai? ?
aeeeaaeai? iniaenoi caeiaoaa/ai.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Aieiai? iieiaeaiiy aeena?oaoe??
iia?aeiieai? ia ieaioi? “Aeooaeuei? ieoaiiy aa??ao??? o ee?i?oe?
aioo??oi?o oai?ia” (?inoia-ia-Aeiio, 1992), II iaoe?iiaeueiiio eiia?an?
aa?iioieia?a ? aa??ao??a Oe?a?ie (Ee?a, 1994), XV i?aeia?iaei?e
eiioa?aioe?? c ??aeeeo e?enoae?a (Oai?ueia, Aoaeaiaoo, 1994),
i?aeia?iaei?e eiioa?aioe?? c eaca??a (Eaiaaea, Eaaaae, 1994), III
??caeayi?e eiioa?aioe?? c o?ceee ? o?i?? ??aeeeo e?enoae?a ?inoeoooo
o?ceee IAI Oe?a?ie (Ee?a, 1995), XV aaia?aeuei?e eiioa?aioe?? c a’yceeo
?a/iaei (?oae?y, Iaa?a, 1996), XVII eiioa?aioe?? e?a?i NIAe c
aeenia?nieo nenoai (Iaeana, 1996), III i?aeia?iaeiiio c’?cae? c
e?io?iiieo ??aeeeo e?enoae?a (?aaiiai, 1997).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 24 ?iaioe, c yeeo
1 — iiiiin?aia iiiia?ao?y, 13 — noaoae o iaoeiaeo aeo?iaeao (9 —
naiino?eieo), 1 — iaoaio (o ni?aaaoi?noa?), 9 — o iaoa??aeao
eiioa?aioe?e ? c’?cae?a.

Ianya ? no?oeoo?a ?iaioe. Aeena?oaoe?y aeeeaaeaia ia 299 noi??ieao eoaee
aoiaeyoue anooi ? iniiaia /anoeia, ui i?noeoue iaeyae e?oa?aoo?e
(1 ?icae?e), iaoiaee aeine?aeaeaiiy (1 ?icae?e), ee?i?/i? oa
aenia?eiaioaeuei? aeine?aeaeaiiy (7 ?icae?e?a), aiae?c oa ocaaaeueiaiiy
?acoeueoao?a aeine?aeaeaiiy, aeniiaee. Aeena?oaoe?y i?noeoue 40
oaaeeoeue oa 49 ?enoie?a, ui noaiiaeoue 13 ? 22 noi??iee a?aeiia?aeii.
Nienie e?oa?aoo?e aeeth/a? 473 iaeiaioaaiiy (267 ?ia?o a/aieo
a?o/eciyieo oa e?a?i NIAe ? 206 i?aoeue ?iicaiieo aaoi??a) ia
60 noi??ieao.

ci?no ?iaioe

Oa?aeoa?enoeea iaoiaeieia?? oa iaoiae?a aeine?aeaeaiiy. Aeine?aeaeoaai?
o?aaiaioe o?aaeaieo aoa?ineea?icii a?oa??e 24 oai?eo (on? /ieia?ee a?eii
47-65 ?ie?a) io?eiai? i?ae /an o??o?a?/ieo ao?o/aiue, i?iaaaeaieo c
i?eaiaeo iae?oa?oth/iai aoa?ineea?ico noaeei ieaei?o e?ioe?aie. Aeey
eiio?ieueieo aeine?aeaeaiue aeei?enoiaoaaee o?aaiaioe a?oa??e aac iciae
aoa?ineea?ico, io?eiai? i?e iia?aoeaieo ao?o/aiiyo o ca’yceo c oyaeeeie
o?aaiaie ieaei?o e?ioe?aie. Iioe/i? aeanoeaino? e?i?aeieo aeeth/aiue
?ioeiaeueii? iaieiiee aea/aee ca aeiiiiiaith iiey?ecaoe?eii?
i?e?ineii??, aeaeo?e/i? aeanoeaino? — oeyoii aecia/aiiy iiaa?oiaai? oa
ia’?iii? eiioeaio?aoe?? aeaeo?e/ii ca?yaeaeaieo oeaio??a iaoiaeii
aieueooa?aaeieo oa?aeoa?enoee.

Ia iniia? ii??aiyeueiiai oa ei?aeyoe?eiiai aiae?co eiioeaio?aoe?e
e?i?ae?a o ieaci? e?ia? oa ae?eyieao ?ioeie c ??cieie aoa?ineea?ioe/ieie
aeaiaioaie (EIi, OA e AA), ye? aecia/aeeny o 23 oai?eo ca aeiiiiiaith
oiieioa?iai? o?iiaoia?ao??, ?iaeee aeniiaee i?i e?iii?ioa?aeiee
o?ainii?o i?ae e?ia’th oa a?oa??aeueiith no?ieith.

Noai i?ioean?a IIE o ieaci? e?ia? oa a?oa??aeuei?e no?ioe? 27 oai?eo
eiio?iethaaee ca noaiii aeoeaiino? aeooao?ii?aaeoeoace oa
aeooao?iiia?ieneaeace, a oaeiae eiioeaio?aoe?e iaeiiiaiai
ae?aeueaeaa?aeo, ae??iiaeo eii’thaao?a, eaeoaoo, i??oaaoo, iaeaoo oa
ienaeiaoeaoaoo.

Aeine?aeaeoaaee aieea AoAe, aeaioiaeaieo aii?oieo oa
??aeeiiie?enoae?/ieo noi?oae ao???a ON ia oa?aeoa? ?inoo oa
i?ie?oa?aoeaio aeoeai?noue ee?oeiieo eoeueoo? — aia??iiaeueieo
o?a?iaeano?a ethaeeie ? ee?oei e?i?? CaOv (i?iaaaeaii 8 na??e
aeine?aeaeaiue), a oaeiae ?ciaeaeo?e/ii? oa c aeanoeainoyie
naaiaoiaeaeo?ee?a eiiiiceoe?e, ui aeeth/athoue o naaa iio?aeia
oa?oai?eo, ia no?oeoo?io i?aai?caoe?th oa i?ie?oa?aoeaio aeoeai?noue
ee?oeiieo aeaiaio?a a?oa??aeueii? no?iee aenia?eiaioaeueieo oaa?ei
(aeei?enoaii 11 niaae). ?acoeueoaoe io?eioaaee ca aeiiiiiaith na?oeiai?
i?e?ineii??, 3I-oei?aeeiiai? iicia/ee oa iioieiai? oeeoioeoi?eiao???.

Aiae?c ei?aeyoe?eieo ca’yce?a i?ae iieacieeii caeaoiino? e?i?aeii?
o?aeoe?? ieacie e?ia? aei ooai?aiiy ??aeeiiie?enoae?/ii? oace oa
iieacieeaie aa?aaaoe?eii? ooieoe?? o?iiaioeeo?a, aeine?aeaeaii? ca
aeiiiiiaith ?ic?iaeaiiai niiniao, aeaa ciiao ioe?ieoe cia/aiiy
iaciii?oiiai noaio ieaciaoe/ii? iaia?aie oeeo ee?oei a aa?aaaoe?eiiio
i?ioean?.

Aeey ioe?iee o 100 /ieia?e (30 i?aeoe/ii caei?iaeo in?a ? 70 oai?eo ia
?ON) caeaoiino? e?i?aeii? o?aeoe?? ieacie e?ia? aei ooai?aiiy
??aeeiiie?enoae?/ii? oace c iaoith ae?aaiinoeee aoa?iaaiieo
aeene?i?aeai?e canoiniaoaaee eaca?io aeeo?aeoiiao??th. Ae?aaiinoe/ia
cia/aiiy niiniao iaa?oioiaoaaee aeiiea?aia?ia?ao?/iei aeine?aeaeaiiyi.

Aea??ee ii??aithaaee ca aeiiiiiaith ia?aiao?e/iiai oa iaia?aiao?e/iiai
e?eoa???a Nouethaeaioa, ia?aiao?e/iiai e?eoa??th O?oa?a, ??cieoeth
/anoio — e?eoa??th “o?-eaaae?ao”. I?e aecia/aii? caeaaeiino? aa??aoe??
iaeieo e?euee?nieo iieaciee?a a?ae ?ioeo canoiniaoaaee eiao?oe??io
ei?aeyoe?? r. Ia?iaeo ?acoeueoao?a iioieiai? oeeoioeoi?eiao??? a
eii?aeeiaoao ?iciiae?eo ee?oei ca oacaie ee?oeiiiai oeeeeo i?iaiaeeee ca
aeiiiiiaith ?ic?iaeaieo aeey AII aeai?eoi?a ? i?ia?ai. Iaoaiaoe/ia
iiaeaethaaiiy e?enoaeio?i?/ieo aeanoeainoae e?i?ae?a ?ioeie
cae?enithaaee iaoiaeii aaaaoiaei??ii? ?aa?an?? ca aeiiiiiaith
eiii’thoa?ii? i?ia?aie Mathcad 7.0 Professional.

Aenia?eiaioaeuei? aeine?aeaeaiiy aeeiiai? o a?aeiia?aeiino? aei “I?aaee
i?iaaaeaiiy ?ia?o c aeei?enoaiiyi aenia?eiaioaeueieo oaa?ei” (Iaeac IIC
O?N? ? 601 a?ae 17.09.87 ?.).

O ?icae?eao 4 – 9 aeeeaaeai? ianooii? ?acoeueoaoe ?iaioe. I?e
aeine?aeaeaii? o iiey?eciaaiiio na?oe? ae?eyiie ?ioeiaeueii? iaieiiee
o?aaiaio?a a?oa??e c EIi, io?eiaieo a?ae in?a aac iciae ae?aaeaiiai
aoa?ineea?ico, o iaaeao o?c?ieia?/ieo oaiia?aoo? (37 – 38,5 °N)
??aeeiiie?enoae?/i? aeeth/aiiy, ye i?aaeei, ia aeyaeyee aai a aeayeeo
iieyo ci?o i?e?ineiio ciaoiaeeee iiiaeeiie? ?icoaoiaai? a ee?oei?
e?enoaee. Inoaii? aeyaeyee neaaeee nooi?iue iioe/ii? ai?cio?ii?? ?, o
ca’yceo c oeei, iaaeinoaoiuei /?oei a?coae?coaaeeny. Aeine?aeaeaiiy oeo
naieo i?aia?ao?a o a?eueo oe?ieiio oaiia?aoo?iiio ?ioa?aae? iieacaei, ui
i?e a?eueo iecueeeo oaiia?aoo?ao (25 – 29 °N), ye i?aaeei, a iieyo ci?o
??aeeiiie?enoae?/ieo aeeth/aiue aoei iaaaaaoi (2 – 6), a i?e
oaiia?aoo?ao 30 – 34 °N e?euee?noue iaciii?oieo no?oeoo?, ?icoaoiaaieo a
ee?oeiao, ??cei ca?eueooaaeanue. I?e i?aeaeuaii? oaiia?aoo?e aei 35 °N ?
a?eueoa aieiaia iana e?i?ae?a ciiao iaaoaaea ?cio?iiieo aeanoeainoae.

I?e aeine?aeaeaii? ae?eyiie ?ioeie o?aaiaio?a a?oa??e c EIi, io?eiaieo
a?ae oai?eo c oyaeeeie oi?iaie aoa?ineea?ico, a iaaeao o?c?ieia?/ieo
oaiia?aoo? ii?yae c ??aeeiiie?enoae?/ieie aeeth/aiiyie, ?icoaoiaaieie a
ee?oei?, /anoi aeyaeyee a?eueo aaeee? iicaee?oeii? neoi/aiiy iaciii?oieo
e?i?ae?a. I?e oeueiio o?aaa caaaeeoe ia oa, ui a aeine?aeaeoaaieo EIi
iaee i?noea ii/aoeia? yaeua o?a?ico (o??o?a?/i?e ?aeiino?oeoe??
i?aeaeaaaee noaeeie, ye? aoee cia/iith i??ith o?aaeai? aoa?ineea?icii ?
noaiiciaai?). Ia noaae?? OA e?euee?noue iicaee?oeiieo
??aeeiiie?enoae?/ieo e?i?aeieo neoi/aiue, ui ceeaathoueny o aaeee?
eiiaeiia?aoe, i?e oaiia?aoo?? 37 – 38,5 °N cia/ii ca?eueooaaeanue, a ia
noaae?? AA ai?cio?iii? e?i?aee aoa?iiaoicieo ian iaeaea iiai?noth
caiiaithaaee i?aia?ao.

I?e ?a?no?aoe?? aieueooa?aaeieo oa?aeoa?enoee ae?eyiie ?ioeiaeueii?
iaieiiee c aaoa?iaaiiei o?aaeaiiyi aoa?ineea?ioe/iei i?ioeanii aeyaeaii
aea? oace iiey?ecaoe?? — aioenaaiaoiaeaeo?e/ia oa naaiaoiaeaeo?e/ia. I?i
oea na?ae/eoue iayai?noue niiioaiii? iiey?ecaoe?? — cia/ia ? aaeueie
??cea, aea ana ae /ano?oa aacia?a?aia ca?eueoaiiy ca?yaeo
aeine?aeaeoaaieo ia’?eo?a i?e e?eoe/ieo cia/aiiyo iaeeaaeaiiai
aeaeo?e/iiai iiey. sse aeaeii c oaaeeoe? 1, i?e ca?eueoaii?
iai?oaeaiino? aeaeo?e/iiai iiey (0 ? 5 A) aaee/eia niiioaiii?
iiey?ecaoe?? a NO ia?aaeuoaaea aaee/eio iiey?ecaoe?? a ANO i?e
aeine?aeaeaii? c?ace?a c EIi o 48,7 ?ace (p < 0,001), OA — o 30,9 ?ace (p < 0,001) e AA — o 34,9 ?ace (p < < 0,001). I?e cieaeaii? iai?oaeaiino? aeaeo?e/iiai iiey (5 ? 0 A), iaaiaee, niinoa??aaee ia?ao?ae NO o ANO, i?ae /an yeiai aaee/eia iiey?ecaoe?? ciaioeeany o 96,3 ?ace (p > 0,05), 52,6 ?ace (p < 0,001) ? 38,6 ?ace (p < 0,001) a?aeiia?aeii. E?eoe/i? aaee/eie iai?oaeaiino? aeaeo?e/iiai iiey, i?e yeeo niinoa??aaee oacia? ia?aoiaee (ANO ? NO), eieeaaeeny o iaaeao 1,43 — 3,03 A. Iaea i?noea iaae?acia oaiaeaioe?y aei ciaioaiiy oe??? aaee/eie c i?ia?anoaaiiyi aoa?ineea?ioe/iiai i?ioeano (EIi ? OA ? AA) ye i?e ia?aoiae? ANO a NO,? oae ? i?e ia?aoiae? NO a ANO (p > 0,05). Ne?ae
a?aecia/eoe, ui aaee/eie iai?oaeaiino? iaeeaaeaiiai a aenia?eiaio?
aeaeo?e/iiai iiey a?aeiia?aeathoue aaee/eiai iai?oaeaiino? aeaeo?e/iiai
iiey, ui aeieea? a oiiaao ?aaeueiiai e?iaioieo [Iieaeaa A.I. e niaao.,
1978]

I?e ca?eueoaii? iai?oaeaiino? aeaeo?e/iiai iiey ?ic?aooiie ca?yae?a a
ANO iieacaa, ui ?oiy aaee/eia a iaeano? OA, ii??aiyii c iaeanoth EIi,
c?inea ia 87,4 % (p < 0,01), a i?e o?ainoi?iaoe?? OA a AA ciaioeeany ia 23,7 % (p < 0,01). A oe?eiio a?ae ii/aoeo ?icaeoeo aoa?ineea?ioe/iiai i?ioeano aei eiai Oaaeeoey 1 ?acoeueoaoe aecia/aiiy aaee/eie ca?yaeo (Q·10-9 Ee) a ANO ? NO ae?eyiie a?oa??aeueii? no?iee c ??cieie noaae?yie aoa?ineea?ico (M m) EIi (n = 9)OA (n = 22)AA (n = 24)ANONOANONOANONO05 A50 A05 A50 A05 A50 A05 A50 A05 A50 A05 A50 A123456 78910111212,2 1,79,1 ±4,5595,9 ±98,1875,5 ±419,122,9 ±5,612,9 ±2,8709,2 ±84,3676,1 ±113,417,5 ±2,814,8 ±2,6610,2 ±45,8569,6 ±49,9 P1-3 0< 0,001 P5-7 0< 0,001 P9-11 0< 0,001 P2-4 0> 0,05

P6-8 0< 0,001 P10-12 0< 0,001 P1-5 0< 0,01* P5-9 0< 0,01* P1-9 0< 0,01* P2-6 0> 0,05*

P6-10 0> 0,05*

P2-10 0> 0,05* P3-7 0> 0,05*

P7-11 0< 0,01* P3-11 0> 0,05*

P4-8  0< 0,05* P8-12 0< 0,05* P4-12 0< 0,05*___________________________________________________________________ _____________________ I?ei?oea: i?e aecia/aii? ??aiy cia/eiino? ?ica?aeiinoae, ia iii?/aiiai c??i/eith, aeei?enoaii iaia?aiao?e/iee e?eoa??e Nouethaeaioa; (*) — aeei?enoaii ia?aiao?e/iee e?eoa??e O?oa?a. 32 caaa?oaiiy (EIi ??AA) aaee/eia ca?yae?a a ANO c?inea ia 43,0 % (p<0,01) (aeea. oaae. 1). I?e cieaeaii? iai?oaeaiino? aeaeo?e/iiai iiey a ANO ca?eueoaiiy ca?yae?a a iaeano? OA, ii??aiyii c iaeanoth EIi, ia 41,4 %, a iaeano? AA, ii??aiyii c iaeanoth OA, ia 14,9 %, a oaeiae a iaeano? AA, ii??aiyii c iaeanoth EIi, ia 5 % ia aoei noaoenoe/ii aeinoia??iei (aeea. oaae. 1). I?e ca?eueoaii? iai?oaeaiino? aeaeo?e/iiai iiey a NO ca?eueoaiiy ca?yae?a a iaeano? OA, ii??aiyii c iaeanoth EIi, ia 19,0 % aoei iaaeinoia??iei, ciaioaiiy a iaeano? AA, ii??aiyii c iaeanoth OA, ia 14,0 % — aeinoia??iei (p < 0,01), a ?ica?aei?noue a ca?yaeao i?ae EIi oa AA iacia/iith ? iaa??ia?aeiith (aeea. oaae. 1).I?e cieaeaii? iai?oaeaiino? aeaeo?e/iiai iiey a NO aeyaeee aeinoia??ia (p < 0,01) ciaioaiiy ca?yae?a a oiae? i?ia?anoaaiiy aoa?ineea?ioe/iiai i?ioeano — EIi ? OA (ia 22,8 %), OA ? AA (ia 15,8 %), a ca?yaee a iaeano? AA aoee iaioa ca?yae?a a iaeano? EIi ia 34,9 % (p < 0,01) (aeea. oaae. 1, ?en. 1). I?e ciyoo? iaeeaaeaiiai ciai? aeaeo?e/iiai iiey o an?o c?aceao ?ioeiaeueii? iaieiiee a?oa??e oai?eo ia aoa?ineea?ic, ui i?noyoue EIi, OA oa AA, aeyaeaii caeeoeiaee ca?yae, yeee ?icaeyaea?oueny ye yaeua a?noa?aceno. Ii??aiyiiy na?aaei?o aaee/ei a?noa?aceno ae?eyiie ?ioeie c ??cieie noaae?yie aoa?ineea?ico (oaae. 2) iieacaei, ui aaee/eia caeeoeiaiai ca?yaeo aoea iaeiaioith o i?noeyo eieae?caoe?? EIi e iii?oii c?inoaea (ia 188,0 %; p < 0,05) o i?noeyo eieae?caoe?? OA. I?e??no aaee/eie ca?yaeo ia ae?eyieao ?ioeie c AA, ii??aiyii c ae?eyieaie ?ioeie c OA, noaiiaea 13,2 % (p < 0,05). A aaee/eia caeeoeiai? iiey?ecaoe?? a iaeano? AA a?eueo i?ae o 3,3 ?ace ia?aaeuoaaea oaeo a iaeano? EIi (p<0,01). Oaaeeoey 2 ?acoeueoaoe aecia/aiiy aaee/eie a?noa?aceno (Q·10-9 Ee) ae?eyiie a?oa??aeueii? no?iee c ??cieie noaae?yie aoa?ineea?ico (M ± m) EIi (n=9)OA (n=22)AA (n=22)?1231—22—33—421,7 ± 4,862,6 ± 12,570,8 ± 11,1< 0,05> 0,05< 0,05I?ei?oea: i?e aecia/aii? ??aiy cia/eiino? ?ica?aeiinoae aeei?enoaii ia?aiao?e/iee e?eoa??e Nouethaeaioa. Aeine?aeaeaiiy aieueooa?aaeieo oa?aeoa?enoee ae?eyiie ?ioeie c EIi o a?oi? in?a, ui ia no?aaeaeathoue iaoiiaeaieie aoa?ineea?icii caoai?thaaiiyie, aeaeo?e/ii? iiey?ecaoe?? ia aeyaeei (Q = 0). Iaaaaeai? ?acoeueoaoe iiey?ecaoe?eii? i?e?ineii?? oa aei???a aieueooa?aaeieo oa?aeoa?enoee a?oa??aeueii? no?iee i?ae /an aoa?ineea?ico aeacothoue ia oa, wmetafile8? ?? ?? ?–???????????? ??????? ????????? ??????? ????? uee??? ???????????ue??????????-?? ???u??????"????-????$?A?y?Cy?C?A??A?y? ???u??????????"????-????ue??yyy??????-?????????-?? ???u??????"????-????$?A?iCiCy?A?y?A?i???-????-??? ??????-?? ???u??????"????-????$?A?OCOCiA?iA?O???-????-??? ??????-?? ???u??????"????-????$?A?AeCAeCOA?OA?Ae???-????-? ????????-?? ???u??????"????-????$?A?±C±CAeA?AeA?±???-????-? ????????-?? ???u??????"????-????$?A??en. 1. Aieueooa?aaei? oa?aeoa?enoeee ae?eyiie ?ioeie c EIi, OA ? AA o NO ui c i?ia?anoaaiiyi aoa?ineea?ico (EIi OA AA) a'yce?noue e?i?ae?a, ye? i?noyoueny a ?ioei? a?oa??e ca?eueoo?oueny, o ca’yceo c /ei oaeiae ca?eueoo?oueny oaiia?aoo?iee ?ioa?aae ?nioaaiiy ??aeeiiie?enoae?/ii? oace, ? aaea ia noaae?? OA aai iaa?oue i?e ii/aoeiaeo iciaeao o?a?ico a iaeano? EIi /anoeia e?i?aeieo aeeth/aiue i?e o?c?ieia?/ieo oaiia?aoo?ao ciaoiaeeoueny a ??aeeiiie?enoae?/iiio noai?. Oiae? ye a iaeano? EIi ?ioeie, yea ia ia? iciae o?a?ioecaoe??, ??aeeiiie?enoae?/ia oaca ?nio? i?e a?eueo iecueeeo oaiia?aoo?ao. Oaeei /eiii, ?oeioaaiiy i?ienoeo ee?oei ?ioeiaeueii? iaieiiee a?oa??e ethaeeie e aeeea e?i?ae?a, ye? i?noyoueny a ieo, o iicaee?oeiiee i?ino??, ui anioe?eiaaii c o?ainoi?iaoe??th EIi a OA [Schwartz C.J. et al., 1991] a?aeaoaa?oueny, i/aaeaeii, o ca’yceo c oaciaei ia?aoiaeii oeeo e?i?ae?a i?e oaiia?aoo?? aioo??oiueiai na?aaeiaeua i?aai?cio (37 – 38,5 °N) c aii?oiiai o ??aeeiiie?enoae?/iee noai. Iicaee?oeii? ??aeeiiie?enoae?/i? neoi/aiiy ??aeeeo e?i?aeieo noi?oae aaoa?iaaiieo aoa?ineea?ioe/ieo aeaiaio?a iathoue naaiaoi ? aioenaaiaoiaeaeo?e/i? aeanoeaino?. Ia?ao?ae ANO a NO a?aeaoaa?oueny i?e oaiia?aoo?? 37 – 38,5 °N e e?eoe/ieo aaee/eiao iai?oaeaiino? iaeeaaeaiiai aeaeo?e/iiai iiey, ii??aiyiieo c aaee/eiaie iai?oaeaiino? aeaeo?e/iiai iiey, ui aeieea? a a?oa??aeueiiio ?one? a ia??iae i?ioiaeaeaiiy ioeueniai? oaee?. A NO iicaee?oeii? e?i?aei? ooai?aiiy a?oa??aeueii? no?iee aeaeo?e/ii iiey?eciaai?. O a?aeiia?aeiino? aei aeaieo oai?aoe/ii? oa aenia?eiaioaeueii? e?enoaeio?ceee [Aio?a C.TH. e niaao., 1989] iiaeia oaa?aeeoe, ui ??aeeiiie?enoae?/i? e?i?aei? no?oeoo?e a?oa??aeueii? no?iee, ye? iathoue naaiaoi e aioenaaiaoiaeaeo?e/i? aeanoeaino?, a aeaeo?iiaai?oiiio iie? i?ae /an i?ioiaeaeaiiy ioeueniai? oaee? oa ia?aiaaeo a?oa??aeueiiai oeneo aeyaeythoue i'?ciaeaeo?e/iee aoaeo. Caaaeath/e ia aeeeaaeaia aeua, ne?ae i?eionoeoe, ui ia iaaiiio aoai? iioiaaiaco, o ca’yceo c ii?ooaiiyie e?iii?ioa?aeiiai neeaaeo ieacie e?ia?, i?yiiai ? cai?ioiiai o?ainii?oo EI i?ae ieaciith e?ia? oa noaeeiiith no?ieith, a inoaii?e aeieeathoue oiiae aeey oi?ioaaiiy e?i?aeieo aeeth/aiue c iacioacieie e naaiaoiaeaeo?e/ieie aeanoeainoyie. Iniaeeaee ?ioa?an noaiiaeyoue ?acoeueoaoe ii??aiyeueiiai aeine?aeaeaiiy ai?noo e?i?ae?a a iaeano? EIi oa OA ye ?oaaaeo, ui ? a?aei?aaiei ioieoii o ii?oiaaiac? aoa?ineea?ioe/ii? aeyoee. Oae, aeinoia??i? eiioeaio?aoe?ei? c?ooaiiy oi?eioeenue OA ? anoa?eo?eiaaiiai ON, ai?no yeeo a?aeiia?aeii ca?eueoeany ia 39,7 oa 30,3 % a OA ii??aiyii c EIi. Ciaioaiiy ai?noo a?eueiiai ON ?acii ?c ca?eueoaiiyi ai?noo anoa?eo?eiaaiiai ON coiiaeei i?aeaeuaiiy eiao?oe??ioa anoa?eo?eaoe?? a 1,9 ?ace. Aaaeeeai oaeiae a?aei?oeoe ??cea cieaeaiiy aei iacia/iiai ei?aeyoe?eiiai ca’yceo ai?noo anoa?eo?eiaaiiai ON o ieaci? e?ia? oa OA ii??aiyii c oaeei o ieaci? oa EIi. Oaeei /eiii, i?eiouaiiy, a?aeiia?aeii aei yeiai ca?eueoaiiy ai?noo anoa?eo?eiaaiiai ON a ?ioei? i?e o?a?ic? iia’ycaia c? ca?eueoaiiyi eiai o?ainii?oo c EIA [Aeoa?o A.I. e niaao., 1981], aeaeyaea? noii?aiei. A?eueo oiai, yeui acyoe aei oaaae ae?acio oaiaeaioe?th aei cieaeaiiy ai?noo a?eueiiai ON (ia 32,2 %), iii?oio oaiaeaioe?th aei cieaeaiiy ai?noo caaaeueiiai ON (ia 13,4 %) oa caaaeueieo e?i?ae?a (ia 10,3 %) i?e o?ainoi?iaoe?? EIi a OA, ne?ae i?eionoeoe, ui o?ainii?o EIA a OA, ii??aiyii c ??aiai o?ainii?oo a EIi, cieaeaiee. Oea i?eiouaiiy i?aeoaa?aeaeo?oueny ciaioaiiyi ei?aeyoe?eieo ca’yce?a ai?noo a?eueiiai ON, anoa?eo?eiaaiiai ON, caaaeueiiai ON ? caaaeueieo e?i?ae?a o ieaci? OA, aenieeo aai iii?oieo o ieaci? e EIi. I?e aiae?c? ei?aeyoe?e ai?noo ?ioeo e?i?ae?a o ieaci? e?ia? e ?ioei? ne?ae a?aei?oeoe ??cei c?ineee iiceoeaiee ca'ycie eiioeaio?aoe?e OE o ieaci? oa OA (o ieaci? oa EIi — iacia/ia). EAA aeeth/athoue a?ey 50 % an?o OE, ui i?noyoueny o o?ainii?oieo EI [Thompson G.R., 1983]. C oeueiai aeieeaa?, ui caeaaeiee a?ae ai?noo a ieaci? ??aaiue OE cia/iith i??ith caaacia/o?oueny EAA. E??i oiai, a?aeiii, ui ia a?aei?io a?ae EIi, aea ON anoa?eo?eo?oueny, aieiaiei /eiii, iea?iiaith eeneioith ca aeiiiiiaith oeaieiiiai oa?iaioo aoeee-EiA: oieanoa?ie-o?ainoa?ace [?aiei A.N., Nie?iia A.I., 1989] (i?e aenia?eiaioaeueiiio aoa?ineea?ic? a?aei?/aii cia/ia i?aeaeuaiiy aeoeaiino? oeueiai oa?iaioo o no?ioe? ai?oe [Brokerhoff H., Jensen R., 1978]), o OA aieiaio e?euee?noue anoa?eo?oeiaaiiai ON noaiiaeoue ON-e?iieaao. ?aaeoe?y anoa?eo?eaoe?? e?iieaaith eeneioith, yea iaeaaeeoue aei /enea iacai?iieo AEE, ia? i?noea o ieaci? e?ia?, aieiaiei /eiii, o /anoeao i?aeo?aeoe?? EAA3 aeeeth/ii ca aeiiiiiaith oa?iaioo eaoeeoei-oieanoa?ie-aoeeeo?ainoa?ace [McIntyre N., Harry D.S., 1992]. Oaeei /eiii, ON-e?iieaao, yeee ciaoiaeyoue o OA, ia? ieaciaiia iioiaeaeaiiy. Aaaaeaiiy oaa?eiai c aenia?eiaioaeueiei aoa?ineea?icii ON c iiaea?eiith iicia/eith (14N oa 3I) i?aeoaa?aeeei, ui a ai?oo ii?yae c a?eueiei ON iaaeoiaeyoue ao??e ON, ye? i?aeaeathoueny /anoeiaiio a?ae?ie?co [Stender S., 1979]. A AA na?aae ao???a ON /anoea ON-ieaaoo ia?aaaaea? [Aeoa?o A.I. e niaao., 1981]. sse a?aeiii, EI ie?aieo eean?a iathoue caeaoi?noue cae?enithaaoe ni?yiiaaiee o?ainii?o ON a i?aai?ci?: EI iecueeeo aonoei — aei ee?oei ??cieo oeaiei, na?aae ieo ? aei ee?oei a?oa??aeueii? no?iee, a EAA, iaaiaee, aeoeaiooaaoe ON c ee?oeiieo iaia?ai oa EI iecueeeo aonoei [Goldstein J.L., Brown M.S. 1987]. Ia iniia? io?eiaieo aeaieo neeaaea?oueny a?aaeaiiy i?i eieaeuei?noue, naeaeoeai?noue oa ??cio ?ioaineai?noue i?yiiai oa cai?ioiiai o?ainii?oo EI i?ae e?ia’th oa a?oa??aeueiith no?ieith ia ??cieo noaae?yo aoa?ineea?ico. Ia noaae?? EIi a ?ioeio i?iieeathoue EIA oa EAA. Ia?o? caaacia/othoue aeinoaaeo ON ? i?aeaeathoueny iaiai?ioiiio eaoaaie?cio, ?io? aeiinyoue ON aei ieacie e?ia?. Ia noaae?? OA o?ainii?o EIA a a?oa??aeueio no?ieo cieaeo?oueny, a i?iieeath/? aei ia? EAA, i/aaeaeii, cia/iith i??ith cao?eiothoueny o oeaieiao ? eaoaaie?cothoue. A ?acoeueoao? ?nioth/ee i?ae ieaciith e?ia? oa EIi aaeain ?iciiae?eo ON ii?ooo?oueny, a ??aaiue anoa?eo?eiaaiiai ON cia/ii c?inoa?. I?e aoa?iiaoic?, yeee ii?oieia?/ii oa?aeoa?eco?oueny oi?ioaaiiyi ae?aaeaii? o?a?icii? eainoee, i?iieeiaiiy a ?ioeio ye EIA, oae ? EAA cia/ii cieaeaia, i?i ui iiaeia noaeeoe, aeoiaey/e c? cieaeaiiy ei?aeyoe?eieo ca’yce?a ai?noo o?aeoe?e e?i?ae?a o ieaci? oa a cii? o?aaeaiiy a?oa??aeueii? no?iee. Aeeeth/aiiy noaiiaeoue iii?oii ca?eueoaia ei?aeyoe?eia caeaaei?noue i?ae eiioeaio?aoe?yie anoa?eo?eiaaiiai ON, yea iaiaaii ? ?acoeueoaoii cieaeaiiy ??aiy anoa?eo?eaoe?? — ia 35,3 % ciaioeeany eiioeaio?aoe?y anoa?eo?eiaaiiai ON, aeaui cieceany eiao?oe??io anoa?eo?eaoe??, ?, oaeei /eiii, a?aeiiaeaiiy ??aiiaaae oeeo i?ioean?a o ieaci? e?ia?, aea eiao?oe??io anoa?eo?eaoe?? neeaa 0,83, ? noaeeiiith no?ieith. Iaoai?cie aea??eiai? i?iieeiino? ie?aieo ae?eyiie ?ioeiaeueii? iaieiiee i?ae /an aoa?ineea?ico caeeoathoueny iac'yniaaieie [Aaa?ei ?.C. e niaao., 1989]. E?enoae?/i? e aeaeo?e/i? aeanoeaino? aaaaoieiiiiiaioieo ??aeeeo e?enoae?a aecia/athoueny noeoii?noth cia/iiai /enea /eiiee?a ? a ia?oo /a?ao o?i?/iei neeaaeii oeeo ?a/iaei. Iaoaiaoe/ia iiaeaeue a?noa?aceno iiaeiia aeeth/aoe an? ia?aiao?e, ui aeinoia??ii aieeaathoue ia eiai aaee/eio. O ca'yceo c a?aenooi?noth ai??i?ii? ?ioi?iaoe?? aoea i?eeiyoa e?i?eia iiaeaeue, ye?noue yei? aecia/aee ca i?i?ioiii iaci?uaii? ioe?iee caeeoeiai? aeenia?n?? ??. Oiio eiai aaee/eia iieno?oueny aaaaoii??iith ?aa?an??th aeaeo: wmetafile8? ??ae??????????? ???????????yyy????.????1?????? ???????  ????&??yyyy?????Ayyycyyy@??A?? ???&? ?MathType???????uAth??????aea cj — ia?aiao?e e?i?eii? iiaeae?, aecia/ai? c oiiae i?i?ioio aaee/eie ???wmetafile8? ??1??????????? ???????????yyy????.????1?????? ??????? `????&??yyyy?????AyyyYyyy@???? ???&? ?MathType??P? ???u?????????"????-?????c????c?C???u~yae?????Ii??aithaaee ny iiaeae?, ui a?ae??ciythoueny e?euee?noth ia?aiao??a ? iine?aeiai?noth aeeth/aiiy ?o o iiaeaeue. Oaeee i?aeo?ae aeicaieea aeae?eeoe cia/ei?, o ?aieao e?i?eii? iiaeae?, oaeoi?e. Io?eiaii oae? /enaeuei? iiaeae?. Aeey aeiaaeeo EIi: wmetafile8? ??J??????????? ???????????yyy????.????1?????? ??????? `@6???&??yyyy?????Ayyy?yyy?6???? ???&? ?MathType?? ???uAy ????Aeey aeiaaeeo OA: wmetafile8? ??o??????????? ???????????yyy????.????1?????? ??????? ` 6???&??yyyy?????Ayyy1/2yyy`6???? ???&? ?MathType?? ???uAy ????Aeey aeiaaeeo AA: wmetafile8? ?? ??????????? ???????????yyy????.????1?????? ??????? ? 7???&??yyyy?????Ayyy»yyy`7??» ?? ???&? ?MathType??a???uAy ????aea AON — /anoea anoa?eo?eiaaiiai oieanoa?eio; AON — /anoea a?eueiiai oieanoa?eio; CON — /anoea caaaeueiiai oieanoa?eio; CE — /anoea caaaeueieo e?i?ae?a. Oaeei /eiii, ni?aa?aeiioaiiy e?i?aeieo eiiiiiaio?a aieeaa? ia ?ici?? aeaeo?e/iiai a?noa?aceno ??aeeie?enoae?/ieo e?i?ae?a ?ioeie a?oa??e. Na?aae e?i?ae?a, ui iaea?eueoith i??ith aecia/athoue a?noa?acen, aa?oi aeae?eeoe OA ? caaaeueiee ON. OA, aoaeo/e iiaiei neeaaeiei ao??ii ae?oea?eio, i?noyoue caeeoee iane/aieo AEE. ?ieue OA ? AEE o iaoiaaiac? aoa?ineea?ico caeeoa?oueny iaaeinoaoiuei c'yniaaiith. Oaeei /eiii, aea/aiiy aieeao aee?ieo eeneio ia oacia? ia?aoiaee e?i?ae?a a?oa??aeueii? no?iee (aii?oiee noai ??aeeie?enoae?/iee noai) ? ?oith aeaeo?e/io iiey?ecaoe?th iiaea yaeyoe niaith ia?niaeoeaiee iai?yiie o e?i?aeieia?/ieo aeine?aeaeaiiyo aoa?iaaiaco. A a?eo?ioeeoao oa ieaci? e?ia? oai?eo ia aoa?ineea?ic, ii??aiyii c a?oiith i?aeoe/ii caei?iaeo in?a, aeyaeaia cia/ia i?aeaeuaiiy eiioeaio?aoe?e iaeiiiaiai ae?aeueaeaa?aeo oa ae??iiaeo eii’thaao?a, ui na?ae/eoue i?i i?aeneeaiiy aeoeaiino? IIE. E??i oiai, a a?eo?ioeeoao niinoa??aaee ca?eueoaiiy ai?noo a?aeiiaeaieo oa ieeneaieo oi?i o?ie?a, oiae? ye a ieaci? aeyaeyeiny ciaioaiiy a aeaa ?ace aeenoeueo?aeieo a?oi. Aeinoia??ia cieaeaiiy ai?noo aeenoeueo?aeieo a?oi o ieaci? i?e ae?aaeai?e oaiaeaioe?? aei iaeiie/aiiy noeueoa?ae?eeueieo a?oi coiiaeei ca?eueoaiiy a?aeiioaiiy SH-/SS-a?oie. Ia oii? aeoeaaoe?? ia?aeenieo i?ioean?a i?ioiaeeei i?aeneeaiiy aeoeaiino? aeooao?ii?aaeoeoace oa aeooao?iiia?ieneaeace — oa?iaio?a, ui aa?ooue o/anoue, a?aeiia?aeii, a i?ioeanao a?aeiiaeaiiy aeooao?iio e ?icuaieaiiy a?ae?iia?ieneae?a. Iaeiie/aiiy a a?eo?ioeeoao a?aeiiaeaiiai iaoaaie?oo iaeaoo ?, ye iane?aeie, cieaeaiiy a?aeiioaiue ieeneaieo iaoaaie?o?a (i??oaaoo, ienaeiaoeaoaoo) aei a?aeiiaeaiiai iaeaoo na?ae/eoue i?i iiaeeeaa cieaeaiiy ooieoe?iioaaiiy eeth/iaeo oa?iaio?a oeeeeo E?aana. O ieaci? e?ia?, ye ? a a?eo?ioeeoao, ca?eueooaaany ai?no iaoaaie?o?a ae?eie?co oa oeeeeo E?aana: a?aeiiaeaieo — eaeoaoa e iaeaoa, ieeneaieo —?ienaeiaoeaoaoa e i??oaaoa. Aiane?aeie oeueiai a ieaci? e?ia? ciaiooaaeenue ni?aa?aeiioaiiy ieeneaiiai iaoaaie?oo i??oaaoo aei a?aeiiaeaieo — eaeoaoo e iaeaoo. Ni?aa?aeiioaiiy ieeneaiiai iaoaaie?oo ienaeiaoeaoaoo aei a?aeiiaeaiiai iaeaoo a ieaci? e?ia? oai?eo ii??aiyii c eiio?ieueiith a?oiith ia ci?ithaaeinue, oiae? ye a a?eo?ioeeoao aoei cieaeaiei. A ?acoeueoao? aiae?co ei?aeyoe?eieo ca’yce?a aeine?aeaeoaaieo iieaciee?a a a?eo?ioeeoao oa a?oa??aeuei?e no?ioe?, a oaeiae o ieaci? e?ia? oa a?oa??aeuei?e no?ioe? anoaiiaeaii iiceoeai? caeaaeiino? i?ae ai?noii SH-a?oi oa iaaaoeaia i?ae ai?noii eaeoaoo i?e aeine?aeaeaii? a?eo?ioeeo?a oa oeaieie no?iee a?oa??e, ui na?ae/eoue i?i i?aeneeaiiy ieenethaaeueieo i?ioean?a ?, ye iane?aeie, ca?eueoaiiy ieeneaiino? aioo??oiueiai ee?oeiiiai na?aaeiaeua a a?oa??yo. Aiae?c ca’yce?a aeine?aeaeoaaieo iieaciee?a ieacie e?ia? e a?oa??aeueii? no?iee aeyaea ei?aeyoe?th, ui noino?oueny o?eueee SH-a?oi. A?aeiii, ui i?aeaeuaiiy eiioeaio?aoe?? a?eueieo ?aaeeeae?a o ??aeeiiie?enoae?/ieo e?i?aeieo no?oeoo?ao cieaeo? oaiia?aoo?i? ia?aiao?e oaciaeo ia?aoiae?a — aii?oiee noai ??aeeiiie?enoae?/iee noai aii?oiee noai [Aeyiaeaia E.E., E?eeooiiaeoen I.E., 1989]. A aeaiee /an ia ??ai? a?iioace aeeneooo?oueny ?ieue ieeneaieo oi?i e?i?ae?a o ?icaeoeo aoa?ineea?ico [Grundy S.M., 1993]. O aeine?aeao ia ia?eoiiaaeueieo iae?ioaaao ieo?, ?ieoaiaaieo c ieeneaieie EIA ethaeeie, iieacaii, ui oe? ee?oeii? aeaiaioe o?ainoi?ioaaeeny o i?ieno? ee?oeie, ye? aeoioeththoue ia ao??e ON (cia/ia iaeiie/aiiy yeeo a?aei?/aia o ee?oeiao, iaaaioaaeaieo aoeaoeeueiaaieie EIA) oa a?ae?iia?ieneaee e?i?ae?a, a i?iaeoeoe ieeneaiiy ON, iaoaaie?ci yeeo cia/iith i??ith a?ae??ciy?oueny a?ae iaoaaie?cio anoa?eo?eiaaiiai ON [Kritharides L. et al., 1993]. C o?aooaaiiyi i?aeaeuaiiy ?ioaineaiino? IIE i?ae /an aoa?ineea?ico iiaeia i/?eoaaoe ia iayai?noue oaeeo naieo i?ienoeo ee?oei a ?ioei?, /a?ac oa ui ieeneai? aea?eaaoe ON ciaeaeaii a eoeueoo?aeueieo aeaaeeii’yciaeo ee?oeiao ai?oe oa aaciina?aaeiuei a no?ioe? o?aaeaieo a?oa??e ethaeeie [Grundy S.M., 1993]. Iaeiae e?enoaeio?ce/i? aeanoeaino? ieeneaieo oi?i e?i?ae?a a?ieia?/iiai iioiaeaeaiiy oa ?oi?o noi?oae ?ai?oa ia aea/aeenue. Iaoaiaoe/ia iiaeaethaaiiy e?enoaeio?i?/ieo aeanoeainoae e?i?ae?a ?ioeie i?e aoa?ineea?ic? a caeaaeiino? a?ae aeoeaiino? IIE aeicaieeei iaea?aeaoe oae? ?acoeueoaoe: o aeiaaeeo AA aeinoaoiueith aeinoia??i?noue ia? eeoa u4 (aeia??/a eiia??i?noue 70 %), o aeiaaeeo OA — eeoa u5 (aeia??/a eiia??i?noue 88 %). O ?acoeueoao? aaee/eia a?noa?aceno ai?ieneio?oueny iaaaaeaieie ieae/a caeaaeiinoyie. Aeey OA: wmetafile8? ??J??????????? ???????????yyy????.????1?????? ??????? @A5???&??yyyy?????Ayyy?yyy?5??i?? ???&? ?MathType?? ???u?th??????ci?uaia caeeoeiaa aeenia?n?y ? = 61,0. Aeey AA: wmetafile8? ????????????? ???????????yyy????.????1?????? ??????? @?+???&??yyyy?????Ayyy?yyy@+??i?? ???&? ?MathType?? ???u?th??????ci?uaia caeeoeiaa aeenia?n?y ? = 32,5. Oaeei /eiii, aeoeai?noue IIE a iaeano? aoa?ineea?ioe/ieo o?aaeaiue aieeaa? ia aaee/eio aeaeo?e/iiai a?noa?aceno ??aeeie?enoae?/ieo e?i?ae?a ?ioeie. Na?aae aeine?aeaeoaaieo iieaciee?a IIE, ui i?e ei?aeyoe?eiiio aiae?c? na?ae/eee i?i caaaeaiee aieea, ne?ae cacia/eoe iaeiiiaee aeueaeaa?ae (aeey aeiaaeeo OA) ? ae??iia? eii'thaaoe (aeey aeiaaeeo AA). I?iaaaeaia aeine?aeaeaiiy iieacaei, ui ie?aeiei i?aeoiaeii o ae??oaii? caaea/? iienaiiy e?enoaeio?i?/ieo aeanoeainoae e?i?ae?a ?ioeie iiaea aooe noai?aiiy iiaeae?, yea aeeth/a? an? a?aeii? o e?enoaeio?i?? ia?aiao?e, ui iiaeooue aecia/aoe ??aeeie?enoae?/i? e aeaeo?e/i? aeanoeaino? oeeo e?i?ae?a. Aeeiai?/i?noue o?i?/ieo ? o?ce/ieo i?ioean?a aeiionea? a?aeiia?aei? ci?ie ia?aiao??a iiaeae? o i?ioean? ?icaeoeo aoa?ineea?ico (EIi OA AA). Oeae i?aeo?ae iio?aao? ?ic?iaee neeaaeii? iaoaiaoe/ii? oai??? ? aaeeei? e?eueeino? oaeoe/iiai iaoa??aeo. Aeine?aeaeoaaee aieea aeao?eoo aoa?iiaoicieo aeyoie oa aeaioiaeaieo ??aeeiiie?enoae?/ii? oa aii?oii? e?i?aeieo noi?oae ia oa?aeoa? ?inoo oa i?ie?oa?aoeaio aeoeai?noue aia??iiaeueieo o?a?iaeano?a ethaeeie, a oaeiae aieea aeuaaeacaieo e?i?aeieo noi?oae ia oa?aeoa? ?inoo oa i?ie?oa?aoeaio aeoeai?noue CaOv. *anoeio eiaeiiai c?acea AoAe, io?eiaiiai noa?eeueii c ai?o iiia?eeo oai?eo, iiia?aaeiuei i?aeaeaaaee oaieia?e ia?iaoe? a nooeeueii-noa?ee?caoe?ei?e oao? i?e T° = 200 °N i?ioyaii 2 aiaeei, ui aeicaieeei ii??aiyoe aieea aoa?iiaoicieo ian c ?iaeoeaiaaieie oa ia?iaeoeaiaaieie oa?iieaa?eueieie oeaieiieie oaeoi?aie ?inoo. Iaeii/anii i?iaaee 8 na??e aeine?aeaeaiue. Ia?aae iin?aii eoeueoo?e aia??iiaeueieo o?a?iaeano?a ethaeeie a I na??? aeine?aeaeaiue ia aei? eoeueoo?aeueieo oeaeii?a ?ici?uoaaee AoAe, ia i?aeaeaiee oaieia?e ia?iaoe?, o II na??? — AoAe, i?aeaeaiee oaieia?e ia?iaoe?, a III na??? — ??aeeiiie?enoae?/io i?e T° =37 °N noi?o oieanoa?eiiaeo ao???a AEE, a IV na??? — aii?oio i?e T° =37 °N noi?o oieanoa?eiiaeo ao???a AEE. V na??y aeine?aeaeaiue c eoeueoo?ith AOE aoea eiio?ieueiith. A VI oa VII na??yo aenia?eiaioo aeine?aeaeaiiy i?iaiaeeee ia ee?oeii?e e?i?? CaOv a?aeiia?aeii c ??aeeiiie?enoae?/iith oa aii?oiith i?e T° =37 °N eiiiiceoe?yie oieanoa?eiiaeo ao???a AEE. VIII na??y aeine?aeaeaiue c eoeueoo?ith CaOv i?aaeea ca eiio?ieueio. O I na??? aenia?eiaioaeueieo aeine?aeaeaiue ia 5 aeiao a?aecia/aee ia?aaaaeii i???ioiaaiee ??no o?a?iaeano?a o iai?yi? AoAe. *a?ac 10 ae?a niinoa??aaee ooai?aiiy nai???aeieo "oeaio??a" ?inoo o?a?iaeano?a a ioi/aii? aoa?iiaoicieo ian, ui i?noyoue aee?iiiae?ai? aeeth/aiiy. Ia 20 aeaiue aeine?aeo AoAe aoa u?eueii ioi/aiee o?a?iaeanoaie ? ?iiae? i?aeaeaaaany aeoeaiiio oaaioeeoico. A eoeueoo?ao II na??? aeine?aeaeaiue, aea aoa?iiaoici? iane iiia?aaeiuei i?aeaeaaaee oaieia?e ia?iaoe?, iii?oieo a?aei?i o ?aaeoe?? ee?oei ia AoAe a?ae eoeueoo? I na??? aeine?aeaeaiue aeyaeaii ia aoei. O III na??? aeine?aeaeaiue ?c noi?ooth oieanoa?eiiaeo ao???a AEE, ??aeeiiie?enoae?/ii? i?e T°=37 °N, ia 5 aeiao iiaeia aoei a?aecia/eoe ci???ioiaaiee a a?e e?i?aeieo ian ??no ee?oeiieo aeaiaio?a, a ia 10 aeaiue neoi/aiiy ye e?i?ae?a oae ? AoAe aeaeyaeaee "oeaio?aie" ?inoo aeey i?ie?oa?oth/eo ee?oei. A IV na??? aeine?aeaeaiue c noi?ooth oieanoa?eiiaeo ao???a AEE, aii?oiith i?e T°=37 °N, ia 5 oa 10 aeiao niinoa?aaeaiiy o?a?iaeanoe ia aeyaeyee noeeueiino? iiey?ecoaaoeny a iai?yi? e?aiaeue e?i?ae?a, a a aeayeeo aeiaaeeao a?aei?/aeiny iaiaaaiiy ee?oei oieeiooe eiioaeoo c ieie. O eoeueoo?ao, ui ?ic?ineeny /a?ac 20 aei?a, aea ee?oeie aeiooaii eiioaeooaaee c aii?oiith e?i?aeiith noi?ooth, o?a?iaeanoe ?icoaoiaoaaeeny acaeiaae e?ath e?i?aeii? e?aie?. Oe? ee?oeie, ia anooiath/e o eiioaeo c e?i?aeaie, ia?inoaee oa ?ieainoethaaee aeacaiee noano?ao. A oie aea /an o aeine?aeao c AoAe oa ??aeeiiie?enoae?/iith e?i?aeiith noi?ooth a?aecia/aee ?oo o?a?iaeano?a ni?yiiaaiee o a?e e?i?aeieo ian oa i?iieeiaiiy eaiaeiieacie aeayeeo c ieo aei e?aeiai? ciie e?i?aeieo e?aiaeue. Oa?aeoa? ?inoo oa i?ie?oa?aoeaia aeoeai?noue ee?oei a eoeueoo?ao I ianaaeo aoee aiaeia?/ieie iienaiiio aeua. O VI oa VII na??yo aeine?ae?a /a?ac 10 ? 20 aei?a aoee a?aecia/ai? ?ica?aeiino? i?ae aeine?aeieie eoeueoo?aie CaOv c ??aeeiiie?enoae?/iith oa aii?oiith i?e T°=37 °N eiiiiceoe?yie oieanoa?eiiaeo ao???a AEE. Oe? ?ica?aeiino? noinoaaeeny oa?aeoa?o aca?iiae?? ee?oei c e?i?aeiith ianith. Oae, o aeine?aeao c aii?oieie e?i?aeaie ia niinoa??aaee aaciina?aaeiuei? aca?iiae?? inoaii?o c ee?oeiieie aeaiaioaie. I?ae ee?oeiaie oa e?i?aeiith ianith aeyaeyee a?eueio a?ae ee?oei u?eeiiiiae?aio ciio. A?eueo oiai, ee?oeie ooai?thaaee e?aeia? oeiiiiae?ai? no?oeoo?e, ye? iaaaaeothoue  aenoeeaiiy ia?iaia?th/iai ai?oae?th, ui neaeeoue ia aacaeuei?e iaia?ai?. Ii?yae c oei, a?aecia/aii i?a?aoe?th ie?aieo ee?oei, a a a?eueo i?ci? no?iee (/a?ac 30 – 35 aei?a) — i?i?inoaiiy aei aeacaii? ii?iaeieie ie?aieo ee?oeiieo oyae?a. Ee?oeie, ui i?a?oaaee aei u?eeiiiiae?aii? ciie aoee ?ic'?aeiai?, ia ?icieanooaaeeny, o ?oi?e oeeoiieaci? i?noeeany iii??ia e?euee?noue oaiieo a?aioe, iiaeeeai, e?i?aeieo aeeth/aiue. ?ioo ea?oeio niinoa??aaee o aeine?aeao c ??aeeiiie?enoae?/iith noi?ooth oieanoa?eiiaeo ao???a AEE. ?c c?inoaiiyi iiiioa?o ee?oeie u?eueii ioi/oaaee e?i?aei? iane. *a?ac 10 – 20 aei?a ei?aeii "ee?oeie – e?i?aeia iana" ia iaa iianthaee /?oei? ae?aciino?. Iiaeia aoei niinoa??aaoe a?inoaiiy ieano?a ee?oei oa ie?aieo ee?oeiieo aeaiaio?a o e?i?aeio iano. *a?ac 30 aei?a ii e?ath e?i?aeieo ieyi oi?ioaaeanue ciia ee?oei, caiiaiaieo oaiieie a?aioeaie. I?e aeine?aeaeaii? aieeao ??aeeiiie?enoae?/ii? oa aii?oii? i?e T°=37 °N eiiiiceoe?e oieanoa?eiiaeo ao???a AEE, a oaeiae ON ia neioac aeaciene?eaiioeea?iiai? eeneioe ca aeiiiiiaith 3I-oei?aeeiiai? iicia/ee c’yniaaii, ui iaciii?oia oi?ia oeeo e?i?ae?a ? ON iathoue i?eaeecii iaeiaeiao aaeueioth/o i?ie?oa?aoeaio aeoeai?noue ee?oei e?i?? CaOv ae?th (NA50 50 % aoaeoeaia aeica.  200 iea/ie). Aaeueioth/ee aieea aii?oii? oi?ie noi?o? oieanoa?eiiaeo ao???a AEE ia i?ie?oa?aoe?th ee?oei aoa a?eueo neaaeei (NA50  300 iea/ie). Ca aeiiiiiaith iioieiai? oeeoioeoi?eiao??? a aenia?eiaio? ia oaa?eiao (aeei?enoiaoaaee niaae) aea/aee aieea iaciii?oii? (ui ia? naaiaoiaeaeo?e/io oaco) oa aii?oii? no?oeoo? ia i?ie?oa?aoeaio aeoeai?noue ee?oei a?oa??e no?iee. I?ney 20-aeaiii? aeniiceoe?? o oeaieiao naaiaoiaeaeo?e/ieo oa ?ciaeaeo?e/ii? eiiiiceoe?e, ii??aiyii c eiio?ieai, i?ie?oa?aoeaia aeoeai?noue ioi/oth/eo ee?oei i?e aca?iiae?? c I, ui aeeth/a? i?aaee iioe/ii aeoeaiee ?ciia? o??aeueiiai aeii?oeo, oa c II, ui aeeth/a? e?aee iioe/ii aeoeaiee ?ciia? o??aeueiiai aeii?oeo, aa??aioaie noi?oae (naaiaoiaeaeo?eee) aeinoia??ii ca?eueoeeany, a?aeiia?aeii ia 21,9 oa 26,4 % (p < 0,01). A oie aea /an ca?eueoaiiy i?oioe/ii? aeoeaiino? i?ae ae??th ?ciaeaeo?e/ii? noi?o?, ui aeeth/a? i?aaee oa e?aee aeoeai? ?ciia?e o??aeueiiai aeii?oeo (III aa??aio), ii??aiyii c eiio?ieai aoei ia oaeei cia/iei (8,2 %) oa iaaeinoia??iei. I?oioe/ia aeoeai?noue, ui aecia/aeany ia ae?eyieao aca?iiae?? oeaieie c I oa II aa??aioaie naaiaoiaeaeo?e/ieo eiiiiceoe?e, ii??aiyii c III aa??aioii, ye ? a ii??aiyii? c eiio?ieai, aoea iii?oii aeuith, a?aeiia?aeii ia 12,6 ? 16,8 % (p < 0,05). ?ica?aeiino? i?ie?oa?aoeaii? aeoeaiino?, ui aecia/aeany i?ae ae??th naaiaoiaeaeo?ee?a, ye? i?noyoue i?aaee oa e?aee ?ciia?e iioe/ii aeoeaieo aeiaaaie (I oa II aa??aioe), aoee iacia/ieie oa iaaeinoia??ieie. I?e aeine?aeaeaii? a?noieia?/ieo i?aia?ao?a ae?eyiie a?oa??aeueii? no?iee c ?iieaioiaaiei I aa??aioii noi?o? (naaiaoiaeaeo?ee) a ioi/aii? oeeo /oaei??aeieo aeeth/aiue ?ioeie aai i?ae?ioeiaeueiiai i?inoi?o niinoa??aaee ?ic?inoaiiy iiaeioaaeueii? oeaieie — ca?eueoaiiy i?iaeoeoe?? o?a?iaeano?a, aieieii oa aii?oii? ?a/iaeie. A a ?yae? aeiaaee?a iaea i?noea i?a?aoe?y aei ?ioeiaeueii? iaieiiee aeaaeeii’yciaeo ee?oei. Iaoiii?oieia?/i? ci?ie a?oa??aeueii? no?iee i?ney ?iieaioaoe?? II aa??aioo noi?o? (oaeiae naaiaoiaeaeo?ee) aoee aiaeia?/ieie iienaiei aeua. ?ioo ea?oeio niinoa??aaee a ae?eyieao oeaieie, ye? aeeth/aee III aa??aio noi?o? (?ciaeaeo?ee). A?aei?ie aoee o a?aenooiino? iano?eueee ae ae?aaeaii? ee?oeiii? ?aaeoe?? ye c aieo ii?aeioaaeueii? oeaieie, oae ? aeaaeeii’yciaeo ee?oei. Nooi?iue aeyaeaiino? iaoiii?oieia?/ieo ci?i o oeueiio aeiaaeeo ia iaaaaaoi ia?aaeuoaaea oae? ia eiio?ieueieo ae?eyieao noaeeiii? no?iee, ye? i?aeaeaaaee oeieai aieee aac aaaaeaiiy yeeo-iaaoaeue ?a/iaei. Oaeei /eiii, eiioaeo ee?oeiieo eoeueoo? (aia??iiaeueieo o?a?iaeano?a ethaeeie oa ee?oei e?i?? CaOv) c e?i?aeieie ??aeeiiie?enoae?/ieie eiiiiiaioaie aeao?eoo aoa?iiaoicieo aeyoie c ?iaeoeaiaaieie oeaieiieie oaeoi?aie ?inoo oaeiae ye ? eiioaeo oeeo eoeueoo? c ??aeeiiie?enoae?/iith noi?ooth ao???a ON i?aeaeuo? i?ie?oa?aoeaio aeoeai?noue oeeo ee?oei. ?iieaioiaai? aei a?oa??aeueii? no?iee aenia?eiaioaeueieo oaa?ei ??aeeiiie?enoae?/i? no?oeoo?e c naaiaoiaeaeo?e/ieie aeanoeainoyie i?aeaeuothoue i?ie?oa?aoeaio aeoeai?noue ioi/oth/eo ee?oeiieo aeaiaio?a oa aeeeeeathoue o?a?ic. C ?ioiai aieo, ye iieacaee aeine?aeaeaiiy, i?iaaaeai? c aeei?enoaiiyi 3I-oei?aeeiiai? iicia/ee, iaeiie/aiiy aioo??oi?o ee?oeiieo e?i?ae?a c ??aeeiiie?enoae?/ieie aeanoeainoyie ni?aaey? oeeoioiene/io ae?th. Aii?oi? no?oeoo?e, ye o aeine?aeao in vitro, oae ? a aeine?aeao in vivo, ia ni?aaeythoue iaoia?ieia?/ii? ae??, iiae?aii? aei ae?? ??aeeeo e?enoae?a. Aeeeaaeaia aeua aeicaiey? aaaaeaoe, ui ??aeeiiie?enoae?/i? e?i?aei? ooai?aiiy caeaoi? aeoeaoaaoe i?ie?oa?aoe?th ee?oeiieo aeaiaio?a oa aeeeeeaoe o?a?iaaiiee aoaeo a ioi/oth/eo oeaieiao a?oa??aeueii? no?iee ?, oaeei /eiii, ?i?oe?thaaoe ii?oiaaiac aoa?ineea?ioe/ii? aeyoee. Iaoia?ieia?/ia ae?y ??aeeiiie?enoae?/ieo e?i?ae?a, i/aaeaeii, iaoiiaeaia aeaeo?e/iith iiey?ecaoe??th ? (aai) iayai?noth ca?yaeo iiaa?oi? inoaii?o. Cai?iiiiiaaia eiioeaioe?y aoa?iaaiaco iineoue oi?aa?naeueiee oa?aeoa?. C ?? aeiiiiiaith iiaeia iiynieoe ia?aaaaeio a?eueo?noue iaeiie/aieo i?e aea/aii? aoa?ineea?ico oaeo?a, ui aein? ia io?eiaee aeinoaoiuei /?oei? ?ioa?i?aoaoe??. Oae, iiaeia aaaaeaoe, ui a?oa??aeueia a?ia?oaic?y, yea ? iaei??th c i?ia?aeieo i?e/ei ?icaeoeo aoa?ineea?ico, i?aeneeth? i'?ciaeaeo?e/iee aoaeo, ui aeieea? a e?i?aeieo ??aeeiiie?enoae?/ieo no?oeoo?ao ?ioeie i?ae /an i?ioiaeaeaiiy ioeueniai? oaee?. Ia?aaaaeio eieae?caoe?th aoa?ineea?ioe/ieo aeaiaio?a o ii/aoeiaeo a?aeae?eao, a oaeiae a i?noeyo aeaei?a oa a?oo?eaoe?e a?oa??aeueiiai ?onea iiaeia iia'ycaoe c oei, ui ye ?ac o oeeo ae?eyieao e?iaiiinii? nenoaie aeniea oaeaee?noue e?iaioieo e oo?aoeaioiee ?oo e?ia? iaoiiaeththoue aeieeiaiiy a?eueo neeueieo aeaeo?iiaai?oieo iie?a ?, oaeei /eiii, a?eueo cia/io aeaeo?e/io iiey?ecaoe?th ??aeeiiie?enoae?/ieo no?oeoo? a iaaeao ae?? oeeo iie?a. Eaeueoeeiic a?oa??aeueii? no?iee i?ae /an aoa?ineea?ico iiaeia ?icaeyaeaoe ye ?acoeueoao eiiiainaoe?? ?iiaie eaeueoe?th aeaeo?e/iiai ca?yaeo iiey?eciaaieo e?i?aeieo aeeth/aiue (oae caaiee o e?enoaeio?ceoe? ?iiiee eiiiainaoe?eiee oa? Aaeueiaieueoea). Aeoeaaoe?y IIE noi?iaiaeaeo?oueny ?ioaineo?eaoe??th aoa?ineea?ioe/iiai i?ioeano, a i?aeaeuaiiy eiioeaio?aoe?? a?eueieo ?aaeeeae?a ci?ith? oaiia?aoo?o oaciaiai ia?aoiaeo aii?oiee noai ??aeeiiie?enoae?/iee noai. E??i oiai, a?eueii?aaeeeaeueia ieeneaiiy ni?ey? iane/aiith AEE, ui ia? cia/aiiy aeey ci?ie e?enoaeio?ce/ieo aeanoeainoae neeaaeieo e?i?aeieo eiiiiceoe?e. C?inoaiiy aaeaino iane/ai? AEE / iaiane/ai? AEE noi?iaiaeaeo?oueny ca?eueoaiiyi ?eceeo ?icaeoeo aoa?ineea?ico. I?ioeaoa?ineea?ioe/io ae?th iathoue iiaaa-3 iaiane/ai? AEE. Iiaeia i?eionoeoe, ui aaeain aeuaaeacaieo AEE iaoiiaeth? aii?oiee aai ??aeeiiie?enoae?/iee noai e?i?ae?a a?oa??aeueii? no?iee. Noaia ??aeeiiie?enoae?/ii? eiioeaioe?? aoa?ineea?ico iaaaaeaia ia ?en. 2. Oaeei /eiii, iaaaaeai? ?acoeueoaoe aeine?aeaeaiue aeicaieythoue c iiaeo iiceoe?e oyaeoe ?ieue ON, aeene?i?aeai?e oa aeene?iii?ioa?aeai?e a aoa?iaaiac?. A?aeiiee iinooeao I.I. Ai?/eiaa “aac oieanoa?eio iaia aoa?ineea?ico”, aeiiiaiaiee A.I. Eeeiiaei: "aac aoa?iaaiieo aeene?i?aeai?e iaia aoa?ineea?ico" o na?oe? io?eiaieo aeaieo iiaeia noi?ioethaaoe oae: "Aac ??aeeiiie?enoae?/ieo e?i?ae?a iaia aoa?ineea?ico". Oei naiei aecia/aii oi/eo noeeaiiy oieanoa?eiiai? (e?iii?ioa?aeii?) oa noaeeiii? eiioeaioe?e aoa?ineea?ico. I?e aea/aii? aca?iica'yceo i?ae caeaoi?noth e?i?aeii? o?aeoe?? ieacie e?ia? aei ooai?aiiy iacioace oa aa?aaaoe?eiith ooieoe??th o?iiaioeeo?a c’yniaaii, ui aaee/eia iaciii?oieo ae?eyiie e?i?aeii? o?aeoe?? ieacie e?ia? iaea aenieee nooi?iue iiceoeaii? ei?aeyoe?eii? caeaaeiino? c iieacieeii T1 (/an ii/aoeo aa?aaaoe??) (p<0,01), iii??io — c iieacieeii T2 (/an aa?aaaoe??) (p<0,01), iii?oio — c iieacieeii T3 (oaeaee?noue aa?aaaoe??) (p<0,01), iii??io, aea noaoenoe/ii iaaeinoia??io — c iieacieeii T4 (/an iaeneiaeueii? aa?aaaoe??) (p>0,05). Ca’ycie iieacieea
caeaoiino? e?i?ae?a ieacie e?ia? aei ooai?aiiy iacioace c iieacieeii T5
(oaeaee?noue aeacaa?aaaoe??) aoa a?aenooi?e.

sse a?aeiii, I oaca aa?aaaoe?? o?iiaioeeo?a oa?aeoa?eco?oueny oaeeie
iieacieeaie aa?aaaoia?aie: /anii niiioaiii? aa?aaaoe?? (T1), a oaeiae,
/anoeiai, oaeaee?noth oa /anii ?iaeoeiaaii? aa?aaaoe?? (T2 oa T3
a?aeiia?aeii) [Ia?eoiaia A.I., e niaao., 1980]. ?ioaineai?noue I oace
aa?aaaoe?eiiai i?ioeano iia’ycothoue c aaee/eiith aeaeo?e/iiai ca?yaeo
ieanoeiie e?ia?, i?e i?aeaeuaii? yei? aa?aaaoe?eia caeaoi?noue
ciaioo?oueny, a i?e cieaeaii? — ca?eueoo?oueny [Eaaoia A.A., e niaao.,
1980]. C?iaeaii i?eiouaiiy, ui I oaca aa?aaaoe?? o?iiaioeeo?a caeaaeeoue
a?ae aeaeo?e/iiai ca?yaeo, iaoiiaeaiiai ??aeeiiie?enoae?/ieie
aeanoeainoyie ieaciaoe/ieo iaia?ai oeeo ee?oei [Aeaaeeie?ia N.N., e
niaao., 1979]. O naith /a?ao ??aeeiiie?enoae?/iee noai ee?oeiieo iaia?ai
aecia/a?oueny ni?aa?aeiioaiiyi e?i?aeieo eiiiiiaio?a, ye? aoiaeyoue aei
?oiueiai neeaaeo. Anoaiiaeaii ei?aeyoe?ei? ca’ycee i?ae ai?noii ON
[Aeaaeeie?ia N.N., e niaao., 1979], e?cieaoeeo?io, no?iaii??e?io,
oinoaoeae?eoie?io [*ayei I.I., 1990], e?iieaai?, a?ao?aeiiiai?,
iea?iiai? oa ?ioeo AEE [Aeaaeeie?ia N.N., e niaao., 1979] o ieaci? e?ia?
oa o?iiaioeeoao. C oeueiai aeieeaa?, ui aeyaeai? ei?aeyoe?ei? ca’ycee
i?ae iieacieeaie aa?aaaoe?eii? ooieoe?? (I oace) oa caeaoi?noth
e?i?aeii? o?aeoe?? ieacie e?ia? aei ooai?aiiy ??aeeiiie?enoae?/ii? oace
na?ae/eoue i?i aaao iacioaciiai noaio iaia?ai o i?ioean? aa?aaaoe??
ieanoeiie e?ia?. Oaeei /eiii, iiaeia i?eionoeoe, ui o oai?eo ia ?ON
i?aeaeuaiiy aa?aaaoe?eii? ooieoe?? o?iiaioeeo?a (I oace) cia/iith i??ith
? iane?aeeii aeene?i?aeai??, ci?i e?i?aeiiai neeaaeo oa
??aeeiiie?enoae?/ieo aeanoeainoae ieaciaoe/ii? iaia?aie oeeo ee?oei.

 

 

Ca aeiiiiiaith eaca?ii? aeeo?aeoiiao??? o i?aia?aoao e?i?aeii? o?aeoe??
ieacie e?ia? an?o ianoaaeaieo in?a aeyaeyee ??aeeiiie?enoae?/i?
aeeth/aiiy, na?aaeiy a?eoiaoe/ia aaee/eia (D) yeeo aa??thaaea a iaaeao
10,18 — 22,32 iei. I?e ii??aiyii? na?aaei?o a?eoiaoe/ieo aaee/ei oeeo
aeeth/aiue o a?oi? iaoe??io?a c ?ON oa a a?oi? in?a aac ee?i?/ii
ae?aaeaieo caoai?thaaiue, ui coiiaeai? aoa?ineea?ioe/iei o?aaeaiiyi,
c’yniaaii, ui a a?oi? oai?eo oeae iieaciee ia?aaeuoaaa oaeee o in?a, ui
ia iathoue ?ON aai ?ioeo caoai?thaaiue, iia’ycaieo c aoa?ineea?icii, ia
13,3 % (oaae. 3).

Oaaeeoey 3

?acoeueoaoe aecia/aiiy na?aaei?o a?eoiaoe/ieo aaee/ei ae?eyiie
e?enoae?caoe?? e?i?aeii? o?aeoe?? ieacie e?ia? o in?a, ui ia oai??thoue
ia iaoiiaeai? aoa?ineea?icii caoai?thaaiiy (eiio?ieueia a?oia),
oa o oai?eo ia ?ON (M ? m), iei

Eiio?ieueia a?oiaOai?? ia ?ON?15,9 ? 0,5718,3 ? 0,29< 0,01 Aiae?c ei?aeyoe?eiiai ca’yceo aeiiea?aia?ia?ao?/iiai iieacieea ?iaeaeno ?acenoaioiino? ai?oe (IR) c iieacieeii na?aaeiuei? aaee/eie ??aeeiiie?enoae?/ieo ae?eyiie e?i?aeii? o?aeoe?? ieacie e?ia? i?iaeaiiino?oaaa iii?oiee, ui iaaeeaea?oueny aei aenieiai, nooi?iue ?oiuei? iaa?iaii? caeaaeiino?. I?e ia/eneaii? eiao?oe??io?a ei?aeyoe?? IR ai?oe oa caaaeueiii?eeiyoeo o ee?i?/i?e i?aeoeoe? ia?ea??a aoa?ineea?ico — eiioeaio?aoe?e caaaeueiiai ON, i?a-?-EI, ?-EI, ON ?-EI, ON ?-EI, oa eiao?oe??ioa aoa?iaaiiino? c’yniaaii, ui aaee/eie oeeo eiao?oe??io?a iaio aaaii? (oaae. 4). Oaeei /eiii, ii??aiyeueiee aiae?c aeaieo iieacaa, ui o oai?eo ia aoa?ineea?ic na?aaeiy a?eoiaoe/ia aaee/eia ??aeeiiie?enoae?/ieo /anoeiie aeinoia??ii ia?aaeuo? oaeo o in?a, ui ia iathoue ee?i?/ii ae?aaeaieo caoai?thaaiue, ye? coiiaeai? aoa?ineea?icii. Aeecueeee aei aenieiai nooi?iue iaaaoeaiiai ei?aeyoe?eiiai ca’yceo i?ae IR ai?oe oa na?aaeiueia?eoiaoe/iith aaee/eiith ??aeeiiie?enoae?/ieo ooai?aiue na?ae/eoue oaeiae i?i oa, ui i?ia?anoaaiiy aoa?ineea?ioe/iiai i?ioeano noi?iaiaeaeo?oueny ca?eueoaiiyi ?ici???a oeeo iaciii?oieo aeeth/aiue. Ae?aiacii ii?iaeueieo cia/aiue na?aaeiuei? aaee/eie iaciii?oieo /anoeiie ia/enethaaee o a?aeiia?aeiino? aei i?eeiyoiai o e?i?aeieia?? aecia/aiiy ii?ie aeey ?ioeo e?i?aeieia?/ieo iieaciee?a ye M 10 % [Eeeiia A.I., Ieeoeue/aaa I.A., 1995]. A ?acoeueoao? i?iaaaeaieo ia/eneaiue iaae? ii?ie ae?eyiie e?enoae?caoe?? noaiiaeee 10,92 — 16,80 iei. Oaaeeoey 4 Oa?aeoa?enoeea ei?aeyoe?eieo ca’yce?a aaee/eie IR ai?oe c na?aaeiueith aaee/eiith ??aeeiiie?enoae?/ieo aeeth/aiue e?i?aeii? o?aeoe?? ieacie e?ia? e eiioeaio?aoe?yie e?i?ae?a oa EI ieacie e?ia? (n = 100) IieacieerpNa?aaeiy a?eoiaoe/ia aaee/eia ??aeeiiie?enoae?/ieo aeeth/aiue e?i?aeii? o?aeoe?? ieacie e?ia? Caaaeueiee ON i?a-?-EI ?-EI ON ?-EI ON ?-EI Eiao?oe??io aoa?iaaiiino? -0,64 -0,43 -0,31 -0,30 -0,27 0,41 -0,52 < 0,01 < 0,01 < 0,05 < 0,05 < 0,05 < 0,01 < 0,01 I?e ii??aiyii? ?acoeueoao?a aeine?aeaeaiiy e?i?aeii? o?aeoe?? ieacie e?ia? i?aeoe/ii caei?iaeo in?a oa iaoe??io?a c ?ON c’yniaaii, ui na?aaeiy a?eoiaoe/ia aaee/eia ??aeeiiie?enoae?/ieo /anoeiie o inoaii?o ia?aaeuo? oaeo o a?oi? i?aeoe/ii caei?iaeo ethaeae ia 32,0 % (oaae. 5). Oaaeeoey 5 ?acoeueoaoe aecia/aiiy na?aaei?o a?eoiaoe/ieo aaee/ei ae?eyiie e?enoae?caoe?? e?i?aeii? o?aeoe?? ieacie e?ia? o caei?iaeo in?a oa oai?eo ia ?ON (M ? m), iei Eiio?ieueia a?oia (n=30)Oai?? ia ?ON (n=70)p13,9 ? 0,4418,3 ? 0,29< 0,001 O a?aeiia?aeiino? aei aecia/aii? ii?ie na?aae 70 oai?eo ia ?ON ca?eueoaiiy na?aaeiueiai ?ici??o ??aeeiiie?enoae?/ieo aeeth/aiue aeyaeaii o 49 (70 %), oiae? ye na?aae 30 in?a aac ee?i?/ii ae?aaeaieo caoai?thaaiue, ui coiiaeai? aoa?ineea?icii, o 8 (26,7 %), ui ca?aeii c? noaoenoe/iith ioe?ieith noaiiaeoue aeinoia??io ??cieoeth (p<0,001). Aeniiaee 1. Oieanoa?eiiaa, o no/ani?e ?ioai?aoaoe?? — e?iii?ioa?aeia, oai??y aoa?iaaiaco ? iaea?eueo iaa?oioiaaiith ? io?eiaea oe?iea iioe?aiiy. Aiaeii/an, caeeoa?oueny iac'yniaaiei iecea aaaeeeaeo ieoaiue, ui noinothoueny aoa?ineea?ico, na?aae yeeo aieiaieie ?: § iaoai?ci i?e/eiii-iane?aeeiaiai ca'yceo a?ia?oieanoa?eiai??, aeene?iii?ioa?aeai?? ? e?i?aeii? ?io?eueo?aoe?? ?ioeie c ii?oiaaiacii aoa?ineea?ioe/ii? aeyoee; § iniaeeaino? i?yiiai e cai?ioiiai o?ainii?oo oieanoa?eio oa ?ioeo e?i?ae?a i?ae ieaciith e?ia? ? ae?eyieaie a?oa??aeueii? no?iee c ??ciith ae?aaeai?noth aoa?ineea?ioe/iiai i?ioeano; § cia/aiiy ??aeeie?enoae?/iiai noaio e?i?ae?a ?ioeie a?oa??e a aoa?iaaiac?; § e?i?aeieia?/i? iieacieee, ui aeei?enoiaothoueny o ee?i?oe?, iaaeinoaoiueith i??ith a?aeaeaathoue ??aaiue aoa?iaaiieo ii?ooaiue o nenoai? e?i?aeiiai iai?io. Oaeei /eiii, ne?ae aeciaoe, ui o aeaiee /an a?aenooiy oi?aa?naeueia oai??y aoa?ineea?ico, yea iiaea a ?ioai?aooaaoe e ia'?aeiaoe iaeiie/ai? i?e aea/aii? aoa?iaaiaco oaeoe. Ae??oaiiy cacia/aieo ieoaiue aeicaieeoue ci?oeieoe iiceoe?? oieanoa?eiiai? (e?iii?ioa?aeii?) oai???, eiinie?aeoaaoe ?? c ?ioeie eiioeaioe?yie, o oiio /ene? noaeeiiith oa ia?aeeniith, ? iiaea neoaoaaoe iniiaith aeey ?ic?iaee ?ioi?iaoeaieo iaoiae?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e, a o ia?niaeoea? — aoaeoeaieo iaoiae?a e?eoaaiiy ? i?io?eaeoeee aoa?ineea?ico. 2. In vitro onoaiiaeaii, ui ??aeeie?enoae?/i? e?i?aei? eiiiiiaioe aoa?ineea?ioe/ieo o?aaeaiue i?e oaiia?aoo?? 37,5 0,5 N iathoue aioenaaiaoi- oa naaiaoiaeaeo?e/i? aeanoeaino?. Na?aaei? aaee/eie u?eueiino? aeaeo?e/ieo ca?yae?a ??aeeie?enoae?/ieo e?i?ae?a o naaiaoiaeaeo?e/i?e oac? noaiiaeyoue ia ae?eyieao o?ainoi?iaoe?? e?i?aeii? ieyie o o?a?icio aeyoeo (595,9  98,1)9 Ee/ni2, ia noaae?? o?a?icii? aeyoee — (709,2 84,3)9 Ee/ni2, aoa?iiaoicii? aeyoee — (610,2 45,8)9 Ee/ni2. Ca?aeii c caeiiaie e?enoaeio?ceee ??aeeie?enoae?/i? naaiaoiaeaeo?e/i? e?i?aee ?ioeie ca iaaieo oiia ni?iiiaei? aeyaeyoe i'?ciaeaeo?e/i? aeanoeaino?. An? oiiae aeey i?iyao ??aeeie?enoae?/ieie e?i?aeaie ?ioeie naaiaoi – ? i'?ciaeaeo?e/ieo aeanoeainoae a oiiaao aeeoo?ae?yeueiino? aeio?eiothoueny. 3. Ia noaae?? e?i?aeii? ieyie c ieacie e?ia? a ?ioeio i?iieeathoue e?iii?ioa?aee iecueei? oa aeniei? aonoeie. Ia?o? caaacia/othoue aeinoaaeo oieanoa?eio ? i?aeaeathoueny iaiai?ioiiio eaoaaie?cio, ae?oa? — aeiinyoue oieanoa?ei o ieacio e?ia?. Ia noaae?? o?a?icii? aeyoee o?ainii?o e?iii?ioa?ae?a ieceith aonoeie a ?ioeio cieaeo?oueny, a i?iieeath/? aei ia? e?iii?ioa?aee aeniei? aonoeie eaoaaie?cothoue. Ia noaae?? aoa?iiaoico i?iieeiaiiy a ?ioeio e?iii?ioa?ae?a on?o eean?a cieaeaii. Naeaeoeaia ciaioaiiy ?ioaineaiino? i?yiiai e cai?ioiiai o?ainii?oo e?iii?ioa?ae?a ??cii? aonoeie i?ae ieaciith e?ia? e ie?aieie ae?eyieaie ?ioeie, a oaeiae iineeaiiy i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a a a?oa??aeuei?e no?ioe? i?ecaiaeyoue aei ci?ie neeaaeo noia?ieo e?i?ae?a ?ioeiaeueii? iaieiiee. Ni?aa?aeiioaiiy e?i?aeieo eiiiiiaio?a ii?yae c ?ioeie oaeoi?aie aecia/a? aeaeo?e/i? aeanoeaino? ??aeeie?enoae?/ieo noia?ieo e?i?ae?a aoa?ineea?ioe/ieo o?aaeaiue a?oa??e. 4. ?oeioaaiiy i?ienoeo ee?oei ?ioeie c aeeeaii e?i?ae?a ,ui oo?eiothoueny a ieo, o iicaee?oeiiee i?ino?? ? o?ainoi?iaoe?y e?i?aeii? ieyie o o?a?icio aeyoeo anioe?eiaai? c oaciaei ia?aoiaeii i?e o?c?ieia?/ieo oaiia?aoo?ao aioo??oiueiee?oeiieo e?i?ae?a c aii?oiiai o ??aeeie?enoae?/iee noai. 5. A aenia?eiaio? ia ee?oeiieo eoeueoo?ao ? oaa?eiao iicaee?oeii? aeaeo?e/i? ??aee? e?enoaee aeoeaothoue i?ie?oa?aoe?th iaaeieeoi?o ee?oeiieo aeaiaio?a ? aeeeeeathoue o?a?iaaiiee aoaeo a a?oa??aeuei?e no?ioe?. Iaoia?ieia?/ia ae?y ??aeeeo e?enoae?a coiiaeaia i?iyaii ?oi?o aeaeo?e/ieo aeanoeainoae. Aeeeaaeaia aeicaiey? aenoiooe ??aeeie?enoae?/io e?i?aeio eiioeaioe?th aoa?ineea?ico, nooue yei? iieyaa? a oiio, ui aeeth/aiiy e?i?aeieo ??aeeeo e?enoae?a ?ioeie a?oa??e ethaeeie, ye? iathoue niiioaii? aeaeo?e/i? aeanoeaino?, ni?iiiaei? ?i?oe?thaaoe ii?oiaaiac aoa?ineea?ioe/ii? aeyoee. 6. ??aeeie?enoae?/ia eiioeaioe?y eiinie?aeo? oieanoa?eiiao oai??th aoa?ineea?ico c noaeeiiith ? iineoue oi?aa?naeueiee oa?aeoa?, ui aea? iiaeeea?noue iaa?oiooaaoe ?yae a?iioac: § ia?aaaaeia eieae?caoe?y aoa?ineea?ioe/ieo o?aaeaiue o i?ieneiaeueieo a?aeae?eao, i?noeyo aeaei?a ? a?oo?eaoe?e a?oa??aeueiiai ?onea iaoiiaeaia ae?aaeaiith a?eueoith i??ith a oeeo ae?eyieao iai?oaeai?noth aeaeo?iiaai?oiiai iiey ?, ioaea, i?aeneeaiiyi aeaeo?e/ii? iiey?ecaoe?? ??aeeie?enoae?/ieo e?i?aeieo eiiiiiaio?a ?ioeie; § ?i?oe?aoe?y ii?oiaaiaco aoa?ineea?ioe/ii? aeyoee i?ae aieeaii a?oa??aeueii? a?ia?oaic?? ? ?acoeueoaoii i?aeneeaiiy i'?ciaeaeo?e/ii? iiey?ecaoe?? ??aeeie?enoae?/ieo e?i?aeieo eiiiiiaio?a ?ioeie; § eaeueoeeiic i?e aoa?ineea?ic? iaoiiaeaiee iino?eiith eiiiainaoe??th aeaeo?e/iiai ca?yaeo ??aeeie?enoae?/ieo e?i?aeieo eiiiiiaio?a ?ioeie ?iiaie eaeueoe?th; § iaoai?ci aoa?iaaiii? ae?? aeoeaaoe?? nenoaie ia?aeeniiai ieeneaiiy e?i?ae?a ?aae?co?oueny aiane?aeie oaciaiai ia?aoiaeo e?i?ae?a ?ioeie — aii?oiee noai  ??aeeie?enoae?/iee noai; § iaoai?ci aoa?iaaiii? ? i?ioeaoa?iaaiii? ae?? iane/aieo ? aenieiiaiane/aieo aee?ieo eeneio a?aeiia?aeii ?aae?co?oueny aiane?aeie ci?ie oiia oaciaiai ia?aoiaeo — aii?oiee noai  ??aeeie?enoae?/iee noai; § eieaeueia iaeiie/aiiy anoa?eo?eiaaiiai oieanoa?eio e?iii?ioa?ae?a aeniei? aonoeie a a?oa??aeuei?e no?ioe? ? oaciaee ia?ao?ae e?i?ae?a e?i?aeii? ieyie — aii?oiee noai  ??aeeie?enoae?/iee noai ? oaeoi?ii, ui ?i?oe?th? ii?oiaaiac aoa?ineea?ioe/ii? aeyoee. 7. ??aeeie?enoae?/i? aeanoeaino? ieaciaoe/ieo iaia?ai o?iiaioeeo?a cia/iith i??ith aecia/athoue aa?aaaoe?eiee i?ioean oeeo ee?oei ? ?aae?cothoue iaoai?ci i?aeaeuaiiy ooieoe?? aa?aaaoe?? (?? I oace) i?e aoa?iaaiieo aeene?i?aeai?yo. 8. Ca?eueoaiiy caeaoiino? e?i?aeii? o?aeoe?? ieacie e?ia? aei e?enoae?caoe?? ? ia?ea?ii aoa?ineea?ioe/iiai i?ioeano. O yeino? ae?aaiinoe/iiai e?eoa??th aoa?iaaiii? aeene?i?aeai?? iiaea aooe aeei?enoaia na?aaeiy a?eoiaoe/ia aaee/eia ae?eyiie e?enoae?caoe?? (D) ia i?aeeeaaeeioe? e?i?aeii? o?aeoe?? ieacie e?ia?, aecia/aeueia ca aeiiiiiaith eaca?ii? aeeo?aeoiiao???. I?e cia/aii? D  16,3 iei eiinoaoothoue a?aenooi?noue aoa?iaaiii? aeene?i?aeai??, i?e cia/aii? D  16,3 iei — ?? iayai?noue. Ii??aiyii c ?ioeie e?i?aeieia?/ieie iieacieeaie aoa?iaaiiino? aeene?i?aeai?e — c ai?noii o ieaci? e?ia? caaaeueiiai oieanoa?eio, i?a-?-e?iii?ioa?ae?a, ?-e?iii?ioa?ae?a, oieanoa?eio e?iii?ioa?ae?a aeniei? aonoeie, eiao?oe??ioii aoa?iaaiiino? — iieaciee aecia/aiiy caeaoiino? e?i?aeii? o?aeoe?? ieacie e?ia? aei ooai?aiiy ??aeeie?enoae?/ii? oace ia? i?aeaeuaio /ooeea?noue. i?aeoe*I? ?aeiiaiaeaoe?? “Niin?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e” (iaoaio Oe?a?ie 19490A, IE? G 33/92) cae?enith?oueny oaeei /eiii. C ieacie e?ia? ca iaoiaeii Oie/a aeae?eythoue noia?i? e?i?aee. E?aieth ?ic/eiaieo e?i?ae?a iaiinyoue ia i?aaeiaoia neei ? i?ney aeia?thaaiiy ?ic/eiieea iae?eaathoue iie?eaiei neeii. Aeyaeaiiy ? aecia/aiiy ?ici???a ae?eyiie e?enoae?caoe?? o e?i?aei?e ieyi? cae?eniththoue ca aeiiiiiaith eaca?ii? aeeo?aeoiiao???. sse aeaea?aei na?oea aeei?enoiaothoue aae?e-iaiiiaee eaca?, c aeiaaeeiith oaee? 0,6328 iei. I?ii?iue na?oea, i?iiouaiee /a?ac e?i?aeio ieyio, iiiaaea? ia i?oaiue c iaianaiith n?oeith iiey?ieo eii?aeeiao. Ia i?oai? niinoa??aathoue ieyie, ye? aeieeathoue a ?acoeueoao? ?iciiae?eo aeeo?aaoth/iai ? ?icn?yiiai na?oea aiane?aeie /a?aoaaiiy ae?eyiie c ai?cio?iiieie oa ?cio?iiieie aeanoeainoyie. Io?eiaia ia i?oai? cia?aaeaiiy ?a?no?othoue oioia?ao?/iei iaoiaeii. Aeyaaeaiiy ?iciiae?eo ae?eyiie e?enoae?caoe?? ca ?ici??aie i?iaiaeyoue o a?aeiia?aeiino? c oai???th I?, yea aeei?enoiao? iaaeeaeaiiy aeeo?aeoe?? O?aoiaioa?a aeey aeiaaeeo iaeeo eoo?a ?icn?thaaiiy (< 100) ? a iaeano? iaeiai iiey. I?e aecia/aii? na?aaeiuei? a?eoiaoe/ii? aaee/eie ae?eyiie e?enoae?caoe?? D  16,3 iei — ?iaeoueny aeniiaie i?i a?aenooi?noue aoa?iaaiii? aeene?i?aeai??, i?e D > 16,3 iei — i?i ?? iayai?noue.

?ic?iaeaieee “Niin?a ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e” ia?
i?aeaeuaio /ooeea?noue. I?e ?aae?caoe?? niiniao /enei iia?aoe?e, ui
iaiao?aeii aeeiioaaoe iaaaeeea, aeo?aoe /ano iae?, ui ?iaeoue iiaeeeaei
eiai aeeai?enoaiiy aeey aeni?an-ae?aaiinoeee aoa?iaaiieo aeene?i?aeai?e
ia eeoa o ee?i?/i?e i?aeoeoe?, aea e i?e ianiaeo ai?aeai?ieia?/ieo
ianoaaeaiiyo ianaeaiiy.

Nienie iaoeiaeo ?ia?o, iioae?eiaaiEo CA oaiITH aeena?oaoe??

1. Iieyeia A.A. Eeieaeu, aoa?ineea?ic e o?iiaic. – Iaeanna: AICO E?YIOO,
1997. – 204 n.

2. Iieyeia A.A. AEeaeeie?enoaeee/aneia ninoiyiea eeieaeia e aoa?ineea?ic
(enneaaeiaaiea ia eoeueoo?a eeaoie) // O?c?ieia?/iee aeo?iae. – 1995. –
? 3-4. – N. 90-96.

3. Iieyeia A.A. Enneaaeiaaiea eeieaeia ieaciu e?iae e a?oa?eaeueiie
noaiee o aieueiuo aoa?ineea?icii //Oe?a?inueeee ea?ae?ieia?/iee aeo?iae.
– 1995. – ? 6. – N.32-34.

4. Iieyeia A.?. ??aeeiiie?enoae?/iee (iacioaciee) noai e?i?ae?a oa
i?iiiiae?ai? ee?oeie a?oa??aeueii? no?iee i?ae /an aoa?ineea?ico //
Iaaee/i? ia?niaeoeae. – 1997. – O. ??. – ? 4. – N. 19-21.

5. Iieyeia A.A. AEeaeeie?enoaeee/aneia (iacioaciia) ninoiyiea eeieaeia e
aa?aaaoeey o?iiaioeeoia o aieueiuo eoaie/aneie aieaciueth na?aeoea //
Oe?a?inueeee ea?ae?ieia?/iee aeo?iae. – 1997. – Aei. ??. – ? 4. –
N. 11-13.

6. Iieyeia A.A. Yeaeo?e/aneea aeeaeeea e?enoaeeu e aoa?ineea?ic
(yenia?eiaioaeueiia enneaaeiaaiea) // Oe?a?inueeee ea?ae?ieia?/iee
aeo?iae. – 1997. – Aei. ??. – ? 4. – N. 101-103.

7. Iieyeia A.A. Ii?aaeaeaiea niiniaiinoe eeieaeiie o?aeoeee ieaciu e?iae
e ia?aciaaieth aeeaeeie?enoaeee/aneie oacu eae iaoiae aeeaaiinoeee
aoa?iaaiiuo aeeneeieaeaiee.// Oe?a?inueeee ea?ae?ieia?/iee aeo?iae. –
1997. – Aei. ??. – ? 5. – N. 21-24.

8. Iieyeia A.A. I?ioeaiaoa?ineea?ioe/aneia aeaenoaea eeiii?ioaeaeia
aunieie ieioiinoe – ?aaeueiinoue eee ieo?// Oe?a?inueeee ea?ae?ieia?/iee
aeo?iae. – 1998. – ? 4. – N. 74-77.

9. Iieyeia A.A. Ninoiyiea ia?aeeniiai ieeneaiey eeieaeia a e?iae e
a?oa?eaeueiie noaiea aieueiuo aoa?ineea?icii.// Aanoiee i?iaeai aeieiaee
e iaaeeoeeiu. – 1998. – ? 9. – N. 60-67.

10. Iieyeia A.?. A?oa??aeueia a?ia?oaic?y ? aoa?ineea?ic: a?iioaca
i?e/eiii-iane?aeeiaiai ca’yceo // Iaeanueeee iaaee/iee aeo?iae. – 1998.
– ? 4. – N. 33-35.

11. Iieyeia A.A., Oaae/oe A.I. Yeaeo?e/aneea naienoaa eeieaeia
aoa?ineea?ioe/aneeo ii?aaeaiee a?oa?eaeueiie noaiee /aeiaaea //
Oe?a?inueeee ea?ae?ieia?/iee aeo?iae. – 1997. – Aei. ??. – ? 6. – N.
14-18.

12. Iieyeia A.A., I?ieiiiaa O.I. Eeieaeu, eeiii?ioaeaeu, aoa?ineea?ic e
eoaie/aneay aieaciue na?aeoea (iaci? eeoa?aoo?u) // Oe?a?inueeee
ea?ae?ieia?/iee aeo?iae. – 1998. – ? 9. – N. 5-10.

13. Iieyeia A.A., I?ieiiiaa O.I., Eieiieaoe N.I. Ioeaiea cia/eiinoe
iieacaoaeae oeueo?acaoeiaie niiia?aoee a aeeaaiinoeea
aoa?ineea?ioe/aneiai ii?aaeaiey a?oa?ee // Aanoiee i?iaeai aeieiaee e
iaaeeoeeiu. – 1998. – ? 9. – N. 68-74.

14. Iieyeia A.A., Oaae/oe A.I., Oaeoi E.N. E?enoaeeioeie/aneea naienoaa
eeieaeia a?oa?eaeueiie noaiee i?e aoa?ineea?ica (iaoaiaoe/aneia
iiaeaee?iaaiea) // A?niee i?iaeai a?ieia?? ? iaaeeoeeie – 1998. – ? 22.
– N. 95-99.

15. Iaoaio 19490A Oe?a?ie IEE G ? 33/92. Niin?a ae?aaiinoeee aoa?iaaiieo
aeene?i?aeai?e /A.A. Iieyeia, A.I. TH?eia, I.I. Oaae/oe, ?.I. ?oaeaiei
(Oe?a?ia). – ?  95073442; Cayae. 21.07.95; Iioae. 25.12.97, Athe. 6. –
5 n.

16. Iieyeia A.?. Oaciaee noai e?i?ae?a oa i?iiiiae?ai? ee?oeie
a?oa??aeueii? no?iee ethaeeie // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae
(aeiaeaoie) (Iaoa??aee V eiia?. ea?ae?ieia?a Oe?a?ie 12-14 o?aaiy 1997
?., i. Ee?a). – 1996. – ? 3. – N. 59-60.

17. Iieyeia A.?., TH?eia A.I., Oaae/oe I.I., ?oaeaiei ?.I. A?iioaca
eaeueoe?thaaiiy a?oa??e i?e iayaiino? aoa?ineea?ico // Oe?a?inueeee
ea?ae?ieia?/iee aeo?iae (aeiaeaoie). (Iaoa??aee V eiia?. ea?ae?ieia?a
Oe?a?ie 12-14 o?aaiy 1997 ?., i. Ee?a). – 1996. – ? 3. – N. 60.

18. Iieyeia A.A., TH?eia A.I. Iaciii?oiia ninoiyiea e ninoaa eeieaeia
i?e aoa?ineea?ica a iicaeiai iioiaaiaca // Oacenu aeieeaaeia ieaioia
“Aeo. aii?. aa?ea?o?ee a eeeieea aioo?aiieo aieaciae» (28-30 ai?.
1992 a., ?inoia-ia-Aeiio). – ?inoia-ia-Aeiio, 1992. – N. 129-131.

19. Iieyeia A.?., TH?eia A.I., Oaae/oe I.I., Eieii??oeue N.I.
Ae?aeaeo?e/ia niaeo?ineii?y e?i?aeii? o?aeoe?? ieacie e?ia? oai?eo ia
aoa?ineea?ic // Oace aeii. IV c’?cae ea?ae?ieia?a Oe?a?ie:
(15-17 aa?aniy 1993 ?., Aei?i?iiao?ianuee). – Ee?a, 1993. – N. 27.

20. Iieyeia A.?., Oaae/oe I.I. Eiioeaio?aoe?y aeaeo?e/ii ca?yaeaeaieo
oeaio??a a o?aaeaieo aoa?ineea?icii no?ieao a?oa??e oa aieea
aoa?iiaoiciiai aeao?eoo ia ee?oeiio i?ie?oa?aoe?th // Oace aeii. IV
c’?cae ea?ae?ieia?a Oe?a?ie: (15-17 aa?aniy 1993 ?., Aei?i?iiao?ianuee).
– Ee?a, 1993. – N. 36.

21. Iieyeia A.?. ??aeeie?enoae?/iee noai e?i?ae?a oa i?ie?oa?aoeaia
aeoeai?noue eoeueoo?e aia??iiaeueieo o?a?iaeano?a ethaeeie // Oace aeii.
II iaoe?iiaeueiiai eiia?ano aa?iioieia?a ? aa??ao??a Oe?a?ie:
(4-6 aeiao. 1994 ?., Ee?a): A 2 /. –Ee?a, 1994. – *. II. – N. 516.

22. Poliakov A.E., Yurlov V.M., Fedchouk A.P., Rudenko R.A.,
Shevchenko L.D. Ferroelectric phase transitions in liquid crystalline
state of arteria walls affected by atherosclerosis // 15-th
International Liquid Chrystal Conference (July 3-8, Hungary, Budapest):
Abstracts. – Budapest, 1994. – Vol. 2. – Sessions G-I. –P. 856.

23. Iieyeia A.A., Oaae/oe A.I., ?oaeaiei ?.A., Aa?iye A.I., Oaae/oe A.A.
Naaiaoiyeaeo?e/aneea oaciaua ia?aoiaeu a aeeaeeie?enoaeee/aneie oaca
aauanoaa noaiie a?oa?ee ii?aae?iiuo aoa?ineea?icii // Oac. aeiee. 17-ie
eiio. no?ai NIA “Aeenia?niua nenoaiu”: (23-27 naio. 1996 a., Iaeanna).
–Iaeanna, 1996. – N. 211-212.

24. Aa?iye A.I., Oaae/oe A.I., Iieyeia A.A., Eiaaeue/oe E.E. ?ieue
eeio?iiiie oacu a oi?ie?iaaiee aoa?ineea?ica // III-d International
meeting on lyotropic liquid crystals (December 16-18, 1997, Russia,
Ivanovo): Abstracts. – Ivanovo, 1997. – P. 111.

aAEEO? O OAENO? NEI?I*AIIss

AA — aoa?iiaoicia aeyoea

ANO — aioenaaiaoiaeaeo?e/ia oaca

AoAe — aoa?iiaoiciee aeao?eo

AEE — aee?i? eeneioe

?ON — ?oai?/ia oai?iaa na?oey

EAA — e?iii?ioa?aee aeniei? aonoeie

EIA — e?iii?ioa?aee iecueei? aonoeie

EI — e?iii?ioa?aee

EIi — e?i?aeia ieyia

IIE — ia?aeenia ieeneaiiy e?i?ae?a

NO — naaiaoiaeaeo?e/ia oaca

OA — o?eae?oea?eaee

OA — o?a?icia aeyoea

OE — oinoie?i?aee

ON — oieanoa?ei

CaOv — cancer ovarium

Iieyeia A.?. Cia/aiiy ??aeeiiie?enoae?/iiai (iaciii?oiiai) noaio
e?i?ae?a o iaoiaaiac? aoa?ineea?ico oa ae?aaiinoeoe? aoa?iaaiieo
aeene?i?aeai?e (ee?i?ei-aenia?eiaioaeueia aeine?aeaeaiiy). — ?oeiien.

Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe ca
niaoe?aeuei?noth: 14.01.11 — Ea?ae?ieia?y, Oa?e?anueeee aea?aeaaiee
iaaee/iee oi?aa?neoao, Oa?e?a, 1999.

Aeena?oaoe?y i?enay/aia ieoaiiyi aoa?iaaiaco ? ae?aaiinoeee aoa?iaaiieo
aeene?i?aeai?e. O ?iaio? ?icaeaa?oueny iiaee iai?yiie o ?aieao e?i?aeii?
oai??? aoa?ineea?ico ia iniia? oyaeaiiy i?i eeth/iao ?ieue
??aeeie?enoae?/ieo e?i?ae?a o aoa?iaaiac?. Anoaiiaeaii, ui ii/aoie
aoa?ineea?ioe/iiai i?ioeano anioe?eiaaiee c oaciaei ia?aoiaeii e?i?ae?a
?ioeie c aii?oiiai o ??aeeie?enoae?/iee noai; ??aeeie?enoae?/i? e?i?aee
aoa?ineea?ioe/ieo o?aaeaiue iathoue niiioaii? aeaeo?e/i? aeanoeaino?,
aiane?aeie /iai caeaoi? aeoeaoaaoe ee?oeiio i?ie?oa?aoe?th oa
?i?oe?thaaoe o?a?ic, ui ? noooth ii?oiaaiaco aoa?ineea?ioe/ii? aeyoee.
Iieacaii, ui oi?ioaaiiy e?i?aeaie ??aeeie?enoae?/ii? oace a ?ioei?
a?aeaoaa?oueny aiane?aeie ii?ooaiiy e?i?aeiiai o?ainii?oo — ieacia e?ia?
a?oa??aeueia no?iea. ?ic?iaeaii iaoaiaoe/i? iiaeae?, ui iienothoue
e?enoaeio?i?/i? aeanoeaino? e?i?ae?a. Aeaii ?ioa?i?aoaoe?th iaoai?cio
iineeaiiy aa?aaaoe?? o?iiaioeeo?a (?? I oace) i?e aoa?iaaiieo
aeene?i?aeai?yo. Cai?iiiiiaaii /ooeeaee niin?a ae?aaiinoeee aoa?iaaiieo
aeene?i?aeai?e, ui a?oioo?oueny ia aecia/aii? caeaoiino? e?i?aeii?
o?aeoe?? ieacie e?ia? aei ooai?aiiy ??aeeie?enoae?/ii? oace. Iniiai?
?acoeueoaoe ?iaioe ai?iaaaeaeai? o ee?i?/io i?aeoeeo ? iaa/aeueiee
i?ioean.

Eeth/ia? neiaa: aoa?ineea?ic, e?i?aee, ??aeeiiie?enoae?/iee noai,
ae?aaiinoeea.

Iieyeia A.A. Cia/aiea aeeaeeie?enoaeee/aneiai (iaciii?oiiai) ninoiyiey
eeieaeia a iaoiaaiaca aoa?ineea?ica e aeeaaiinoeea aoa?iaaiiuo
aeeneeieaeaiee (eeeieei-yenia?eiaioaeueiia enneaaeiaaiea). — ?oeiienue.

Aeenna?oaoeey ia nieneaiea iao/iie noaiaie aeieoi?a iaaeeoeeineeo iaoe
ii niaoeeaeueiinoe: 14.01.11 — Ea?aeeieiaey, Oa?ueeianeee
ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Oa?ueeia, 1999.

Aeenna?oaoeey iinayuaia aii?inai aoa?iaaiaca e aeeaaiinoeee aoa?iaaiiuo
aeeneeieaeaiee. A ?aaioa ?acaeaaaony iiaia iai?aaeaiea a eeieaeiie
oai?ee aoa?ineea?ica ia iniiaa i?aaenoaaeaiey i eeth/aaie ?iee
aeeaeeie?enoaeee/aneeo eeieaeia a aoa?iaaiaca.

Enneaaeiaaia eioeia ii?aaeaiiuo aoa?ineea?icii a?oa?ee ieaeieo
eiia/iinoae 24 aieueiuo e ia ii?aaeaiiuo aoa?ineea?icii o 9 aieueiuo.
O?aaiaiou a?oa?ee iieo/aiu ai a?aiy oe?o?ae/aneeo iia?aoeee,
i?iaaaeaiiuo ii iiaiaeo iaeeoa?e?othuaai aoa?ineea?ica e a nayce n
oyaeaeuie o?aaiaie ieaeieo eiia/iinoae.

I?e enneaaeiaaiee i?aia?aoia eioeiu a iiey?eciaaiiii naaoa i?e
oaiia?aoo?a 37 – 38,5 N iieacaii, /oi ia/aei aoa?ineea?ioe/aneiai
i?ioeanna – ?ac?ooaiea iaienouo eeaoie eioeiu – annioeee?iaaii n oaciaui
ia?aoiaeii eeieaeia a?oa?eaeueiie noaiee ec aii?oiiai a
aeeaeeie?enoaeee/aneia ninoiyiea.

In vitro onoaiiaeaii, /oi aeeaeeie?enoaeee/aneea eeieaeu
aoa?ineea?ioe/aneeo yeaiaioia niiniaiu i?iyaeyoue naaiaoi- e
aioenaaiaoiyeaeo?e/aneea naienoaa. Oae, n?aaeiea aaee/eiu ieioiinoe
yeaeo?e/aneeo ca?yaeia a naaiaoiyeaeo?e/aneie oaca ninoaaeee a o/anoeao
o?ainoi?iaoeee eeieaeiiai iyoia a oea?icioth aeyoeo
(595,9  98,1)109 Ee/ni3, ia noaaeee oea?iciie aeyoee —
(709,2  84,3)109 Ee/ni3, aoa?iiaoiciie aeyoee — (610,2  45,8)
109 Ee/ni3.Ana oneiaey aeey i?iyaeaiey aeeaeeie?enoaeee/aneeie eeieaeaie
eioeiu naaiaoi- e iueaciyeaeo?e/aneeo naienoa a oneiaeyo
aeeaeeine?enoaeee/oinoe niaethaeathony.

N?aaieoaeueiue e ei??aeyoeeiiiue aiaeec niaea?aeaiey eeieaeia a ieacia
e?iae e ?acee/iuo ii noaaeeyi aoa?ineea?ioe/aneeo yeaiaioao iicaieee
naeaeaoue neaaeothuea auaiaeu. Ia noaaeee eeieaeiiai iyoia ec ieaciu
e?iae a eioeio i?iieeatho eeiii?ioaeaeu ieceie e aunieie ieioiinoe. Ia
noaaeee oea?iciie aeyoee o?ainii?o eeiii?ioaeaeia ieceie ieioiinoe a
eioeio nieaeaaony, a i?iieeathuea a iaa eeiii?ioaeaeu aunieie ieioiinoe
eaoaaieece?otho. Ia noaaeee aoa?iiaoica i?iieeiiaaiea a eioeio anao
eeannia eeiii?ioaeaeia nieaeaii. Naeaeoeaiia oiaiueoaiea i?yiiai e
ia?aoiiai o?ainii?oa eeiii?ioaeaeia ?acee/iie ieioiinoe i?eaiaeeo e
eciaiaieth ninoaaa noiia?iuo eeieaeia eioeiiie iaiei/ee. Niioiioaiea
eeieaeiuo eiiiiiaioia ia?yaeo n ae?oaeie oaeoi?aie ii?aaeaeyao oaciaia
ninoiyiea noiia?iuo eeieaeia aoa?ineea?ioe/aneeo ii?aaeaiee a?oa?ee.

Iaoaiaoe/aneia iiaeaee?iaaiea e?enoaeeioeie/aneeo naienoa eeieaeia
eioeiu iieacaei, /oi a oi?ie?iaaiee eo yeaeo?e/aneeo naienoa iaeaieueoaa
cia/aiea eiatho iieacaoaee aeieaaiai niaea?aeaiey o?eaeeoea?eaeia e
iauaai oieanoa?eia, a oaeaea eioaineaiinoue ia?aeeniiai ieeneaiey
eeieaeia.

A yenia?eiaioa ia eeaoi/iuo eoeueoo?ao (yia?eiiaeueiua oea?iaeanoe
/aeiaaea e eeaoee eeiee cancer ovarium) e aeeaioiuo (niaaee)
onoaiiaeaii, /oi aiaeeaoi/iua aeeaeeea yeaeo?e/aneea e?enoaeeu
aeoeae?otho i?ieeoa?aoeeth ie?oaeathueo eeaoi/iuo yeaiaioia e
eieoeee?otho oea?ic a a?oa?eaeueiie noaiea. Iaoiaeieiae/aneia aeaenoaea
aeeaeeeo e?enoaeeia iaoneiaeaia i?iyaeaieai eo yeaeo?e/aneeo naienoa.

Eceiaeaiiia iicaieyao ?acaeoue iauai?eciaiioth eeieaeioth oai?eth
aoa?ineea?ica a aeeaeeie?enoaeee/aneoth eiioeaioeeth. Nooue eioi?ie
caeeth/aaony a oii, /oi oaciaue ia?aoiae eeieaeia eioeiu aii?oiiai a
aeeaeeie?enoaeee/aneia ninoiyiea niiniaai eieoeee?iaaoue ii?oiaaiac
aoa?ineea?ioe/aneie aeyoee. AEeaeeie?enoaeee/aneay oai?ey aoa?ineea?ica
iineo oieaa?naeueiue oa?aeoa?. Ia aa iniiaa i?aaeeiaeai ?yae aeiioac.

Ei??aeyoeeiiiue aiaeec iieacaoaeae eeieaeiiai ninoaaa, niiniaiinoe
eeieaeiie o?aeoeee ieaciu e?iae e ia?aciaaieth aeeaeeie?enoaeee/aneie
oacu e aa?aaaoeeiiiie ooieoeee o?iiaioeeoia o 27 aieueiuo eoaie/aneie
aieaciueth na?aeoea iicaieeee i?eeoe e auaiaeo i oii, /oi
aeeaeeie?enoaeee/aneea naienoaa ieaciaoe/aneeo iaia?ai yoeo eeaoie a
cia/eoaeueiie ia?a ii?aaeaeyao aa?aaaoeeiiiue i?ioeann e ?aaeecotho
iaoaieci iiauoaiey ooieoeee aa?aaaoeee (aa I oacu) i?e aoa?iaaiiuo
aeeneeieaeaieyo.

Aeey ioeaiee o 70 aieueiuo eoaie/aneie aieaciueth na?aeoea e
30 i?aeoe/anee caei?iauo eeoe niiniaiinoe eeieaeiie o?aeoeee ieaciu
e?iae e ia?aciaaieth aeeaeeie?enoaeee/aneie oacu n oeaeueth aeeaaiinoeee
aoa?iaaiiuo aeeneeieaeaiee eniieueciaaee eaca?ioth oea?aeoiiao?eth.
Aeeaaiinoe/aneoth cia/eiinoue niiniaa iainiiaaee
aeiiiea?aiaaia?aoe/aneei enneaaeiaaieai. A ea/anoaa aeeaaiinoe/aneiai
e?eoa?ey aoa?iaaiiie aeeneeieaeaiee eniieueciaaee n?aaeithth
a?eoiaoe/aneoth aaee/eio o/anoeia e?enoaeeecaoeee (Ae) ia iiaeeiaeea
eeieaeiie o?aeoeee ieaciu e?iae. I?e cia/aiee Ae  16,3 iei
eiinoaoe?iaaee ionoonoaea aoa?iaaiiie aeeneeieaeaiee, i?e cia/aieyo
Ae > 16,3 iei – a? iaee/ea. *oanoaeoaeueiinoue niiniaa iiaeoaa?aeaeaia
n?aaiaieai n iauai?eiyouie eeieaeieiae/aneeie iieacaoaeyie.

Iniiaiua ?acoeueoaou ?aaiou aiaae?aiu a eeeie/aneoth i?aeoeeo e o/aaiue
i?ioeann.

Eeth/aaua neiaa: aoa?ineea?ic, eeieaeu, aeeaeeie?enoaeee/aneia
ninoiyiea, aeeaaiinoeea.

Polyakov A.E. The significance of liquid crystalline (mesomorphic) state
of lipids in the pathogenesis of atherosclerosis and atherogenic
dislipidemia diagnostics (clinical-experimental exploration). —
Manuscript.

Thesis for a doctor’s degree by speciality 14.01.11 — Nardiology,
Kharkov state medical university, Kharkov, 1999.

The dissertation is devoted to the problem of atherogenesis and
diagnostics atherogenous dislipidemia. The new direction is being
developed within the framework of the lipid theory of an
atherosclerosis. It is based of the idea about a key role of liquid
crystal lipids in atherogenesis. It is estimated that the beginning of
atherosclerotic process is associated with phase transition of intima
lipids from amorphous state to a liquid crystal state. Liquid crystal
lipids of atherosclerotic affections have spontaneous electrical
properties. That makes them capable to activate cell proliferation and
to initiate a fibrosis, that is the essence of a morphogenesis of an
atherosclerotic plaque. It is shown, that formation of a liquid crystal
phase in an intima by lipids occurs owing to infringement of lipid
transport — a blood plasma an arterial wall. The mathematical models
describing crystal-chemical properties of lipids are developed. The
interpreting of the mechanism of intensifying an aggregation of
thrombocytes (of its first phase) at atherogenous dislipidemia is given.
The sensitive way of diagnostics atherogenous dislipidemia is offered,
that is based on definition of ability of a lipid fraction of a blood
plasma to form a liquid crystal phase. The basic results of work are
introduced into clinical practice and educational process.

Key words: atherosclerosis, lipids, liquid crystal state, diagnostics.

I?aeienaii aei ae?oeo 16.09.1999 ?. Oi?iao ???? 1/16.Oi. ae?oe. a?e.
1,9. Oe?aae 100 i?ei.

Iaae?oeiaaii o iie?a?ao?/iiio oeaio?? o??ie Nenoaia-Na?a?n Iaeana,
270078, aoe. Einiiiaao?a, 34, io. 111.Oae.: (0482) 619-130, 698-978

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