I?i?noa?noai ioi?iie caei?ia’y Oe?a?ie

CAII??CUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

OEUAIEI ??eia Aaeaioei?aia

OAeE 616.1-008.6-072:616.12-008.

331.1:616.379-008.64

CIA*AIIss OOIEOe?IIAEUeIEO OA OA?IAEIEIA?*IEO I?IA A IOe?IOe? NOAIO
NA?OeAAI-NOAeEIII? NENOAIE O OAI?EO IA OeOE?IAEE Ae?AAAO OA A?OA??AEUeIO
A?IA?OAIC?TH

14.01.11 — ea?ae?ieia?y

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Caii??aeaey — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Aei?i?iiao?ianuee?e aea?aeaai?e iaaee/i?e aeaaeai??

IIC Oe?a?ie.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

i?ioani? Ia?oeaaa Oaoyia
Ieaen??aia,

Aei?i?iiao?ianueea aea?aeaaia
iaaee/ia aeaaeai?y,

caa?aeoaa/ eaoaae?e
oaeoeueoaonueei? oa?ai?? oa

aiaeie?eiieia??.

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani? Ooooae ?aai Ieoaeeiae/, Caii??cueeee
aea?aeaaiee ?inoeooo oaeineiiaeaiiy e?ea??a IIC Oe?a?ie, caa?aeoaa/
eaoaae?e oa?ai?? ? 2;

aeieoi? iaaee/ieo iaoe, i?ioani? Eiaaeue Na?a?e Ieeieaeiae/, ?inoeooo
oa?ai?? AII Oe?a?ie (i. Oa?e?a), caa?aeoaa/ a?aeae?eo
a?oa??aeueii? a?ia?oii??.

I?ia?aeia onoaiiaa:

?inoeooo ea?ae?ieia?? ?i. I.Ae.No?aaeanea AII Oe?a?ie, a?aeae?e
anaioe?aeueii? a?ia?oaic?? (i. Ee?a).

Caoeno aeena?oaoe?? a?aeaoaeaoueny «_ 26__»_____n?/iy____2000 ?ieo i
«__13 00 » aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae
17.600.02 i?e Caii??cueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? IIC
Oe?a?ie ca aae?anith: 69035, i. Caii??aeaey, i?. Iayeianueeiai, 26.

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Caii??cueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ( 69035, i. Caii??aeaey,

i?. Iayeianueeiai, 26).

Aaoi?aoa?ao ?ic?neaiee «__25___» ____a?oaeiy_____ 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani?
Aieioei I.A.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Na?aae caoai?thaaiue na?oeaai-noaeeiii? nenoaie
ia?oa i?noea ii ?iciianthaeaeaiino? iin?aea? a?oa??aeueia a?ia?oaic?y,
yeo ?a?no?othoue, ca aeaieie AIIC (1996), o 10 — 20 % aei?ineiai
ianaeaiiy a?eueoino? e?a?i na?oo. Aei aea?aeaa c aenieith
?iciianthaeaeai?noth a?oa??aeueii? a?ia?oaic?? a?aeiineoueny ? Oe?a?ia,
a ye?e ca?a?no?iaaii iiiaae 5 iei. oai?eo (Ni??iiaa ?.I. oa ni?aaao.,
1997; Eiaaeaiei A.I. e niaao., 1999). No?eea i?aeaeuaiiy a?oa??aeueiiai
oeneo ni?e/eiy? ?inoeueo, na?oeaao iaaeinoaoi?noue, caoai?thaaiiy ie?ie,
?icoa?oaaiiy ai?oe, ??cei i?aeaeuo? ?ecee ?ioa?eoo i?iea?aea,
ieeethc?eieo caoai?thaaiue ia?eoa?e/ieo noaeei. A?oa??aeueia a?ia?oaic?y
? iaeiei c aieiaieo oaeoi??a eaoaeueiino? a?ae iniiaieo
na?oeaai-noaeeiieo caoai?thaaiue. Cia/ia /anoeia oneeaaeiaiue,
aeiiii?/i? caeoee, aenieee ??aaiue ?iaae?aeiino? oa nia?oiino?, c
iaeiiai aieo, oa ?nioth/? iiaeeeaino? oni?oiiai ei?eaoaaiiy i?aeaeuaiiai
??aiy a?oa??aeueiiai oeneo, c ae?oaiai aieo, coiiaeththoue
aeooaeuei?noue oe??? i?iaeaie.

Iaei??th c iaea?eueo aeooaeueieo i?iaeai ee?i?/ii? iaaeeoeeie
caeeoa?oueny oaeiae oeoe?iaee ae?aaao. Oea iaoiiaeaii eiai cia/iei
iioe?aiiyi, ?aii?i ?icaeoeii oyaeeeo oneeaaeiaiue, ui i?ecaiaeyoue aei
iia??oaiiy yeino? aeeooy, aenieei ??aiai eaoaeueiino?, iaaeinoaoiueith
iiaiioith oyaeaiue i?i ao?ieia?th oa iaoiaaiaoe/i? iaoai?cie
caoai?thaaiiy (Aeaaeia E.E. e niaao., 1994; Aoeiia A.N., 1996).
Ca?aeii c ai?aeai?ieia?/ieie aeine?aeaeaiiyie, iioe?ai?noue oeoe?iaiai
ae?aaaoo iaaieiii ca?eueoo?oueny a on?o e?a?iao na?oo, neeaaeath/e a
i?iieneiai ?icaeiaieo ?aa?iiao a na?aaeiueiio 1,5 — 4 % ianaeaiiy (
Aoeiia A.N. e niaao., 1991; Aaeaaieeei I.E., 1993; Olefsky J.M., Sherwin
R.S., 1985).

Noaeeii? oneeaaeiaiiy ? iniiaiith i?e/eiith ?iaae?aeiino? oa
i?aeaeuaiiy nia?oiino? i?e oeoe?iaiio ae?aaao?. Iniaeeaa i?noea na?aae
caoai?thaaiue na?oeaai-noaeeiii? nenoaie ye i?e ?inoe?icaeaaeiiio, oae
? i?e ?inoe?iiacaeaaeiiio oeoe?iaiio ae?aaao? caeia? a?oa??aeueia
a?ia?oaic?y, /anoioa yei? o oai?eo ia ae?aaao a 1,5 — 2 ?ace ? a?eueoa
ia?aaeuo? iioe?ai?noue a?oa??aeueii? a?ia?oaic?? na?aae ianaeaiiy a
oe?eiio (Aeaaeia E.E. e niaao., 1996; Kingston S.M., Barry G., 1988).

I?iaeaia a?oa??aeueii? a?ia?oaic?? i?e oeoe?iaiio ae?aaao? a inoaii?
?iee ana oe?oa i?eaa?oa? oaaao aeine?aeiee?a. Aea/athoueny oiie?
a?io?i?/i? oa iae?iaoii?aeuei? iaoai?cie, ui aa?ooue o/anoue a ??
?icaeoeo oa noaiiaeaii?; anoaiiaeaia ?ieue aiaeioae?aeueii?
aeenooieoe??, aeoeaaoe?? i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a a ??
i?ia?anoaaii?; i?aeoaa?aeaeaii cia/aiiy i?aeaeuaiiai a?oa??aeueiiai
oeneo a i?ia?anoaaii? ae?aaaoe/ii? iao?iiao??; i?iaeiaaeothoue aea/aoeny
aaiiaeeiai?/i? aniaeoe noaio na?oeaai-noaeeiii? nenoaie i?e
a?oa??aeuei?e a?ia?oaic?? (Eieiiieneay I.A. e niaao., 1989.; E?ooeeiaa
A.A., 1990; Coaeiaa N.O. e niaao., 1991; Oanoaeiaa I.A., Aeaaeia E.E.,
1993; Aoeiia A.N., 1996; Nieieia A.E., Cae/eeiaa I.N., 1996;
Feldt-Rassmussen B. et al., 1987; DCCT, 1993; Nonose N. at al., 1993).

Ne?ae a?aei?oeoe, ui e?eoaaiiy a?oa??aeueii? a?ia?oaic?? i?e oeoe?iaiio
ae?aaao? ? aeaeaei ia ae??oaiith i?iaeaiith. Iacaaaeath/e ia oa, ui
e?ea? aieiae?? aeineoue oe?ieei aeai?ii aioea?ia?oaiceaieo cania?a,
i?aia?aoe, ui aaeeaathoueny aei iei?oiueiai /ano, ia caaaeaee
aoaeoeai?, iathoue aaaaoi iia?/ieo ae?e (Aeaca? A.A., Aeyaeaii
iniaeeaino? eiiiainaoi?ii-i?enoinoaaeueieo ?aaeoe?e na?oeaai-noaeeiii?
nenoaie o a?aeiia?aeue ia ooieoe?iiaeuei? iaaaioaaeoaaeuei? i?iae c
ia?ai?iith iieiaeaiiy o?ea o i?inoi?? o oai?eo ia ??ci? oeie oeoe?iaiai
ae?aaaoo oa a?oa??aeueii? a?ia?oaic??. Anoaiiaeaia ?ioi?iaoeai?noue
ianeaii? i?oinoaoe/ii? oa aioei?oinoaoe/ii? i?ia a ioe?ioe?
?aaeoeaiino? aia?aoa e?iaiia?ao o oeeo eaoaai??e oai?eo. Aia?oa
cae?eniaii ii??aiyeueia aeine?aeaeaiiy aaiiaeeiai?/ieo aoaeo?a eaiioaio
oa aaeaa?cooaio o oai?eo ia oeoe?iaee ae?aaao i?e noi?niiio i?iaaaeaii?
aino?iai oa?iaeieia?/iiai oanoo oa ooieoe?iiaeueieo iaaaioaaeoaaeueieo
i?ia. Anoaiiaeaii a?aei?iiino? aaiiaeeiai?/ii? a?aeiia?ae? ia
iaeii?aciaee i?eeii eaiioaio oa aaeaa?cooaio o oai?eo ia ??ci? oeie
oeoe?iaiai ae?aaaoo, ye? no?aaeaeathoue ia a?ia?oii?/io oai?iao ?
neiioiiaoe/io a?oa??aeueio a?ia?oaic?th. Iieacaii iaiaeiicia/iee aieea
oeeo i?aia?ao?a ia eiiiainaoi?i? ?aaeoe?? na?oeaai-noaeeiii? nenoaie o
oai?eo ia oeoe?iaee ae?aaao.

I?aeoe/ia oe?ii?noue ?iaioe. Canoinoaaiiy eiiieaenii? iaoiaeeee
aeine?aeaeaiiy na?oeaai-noaeeiii? nenoaie ia i?aenoaa?
?aiiie?ea?ae?ia?ao?/iiai iaoiaeo c aeei?enoaiiyi iaaaioaaeoaaeueieo i?ia
aeicaieeei i?iaanoe aeeaiea ??ciia?/ia aea/aiiy ooieoe?iiaeueiiai noaio
nenoaie e?iaiia?ao o oai?eo ia oeoe?iaee ae?aaao, aeyaeoe iniaeeaino?
aaiiaeeiai?ee, oa?aeoa?i? aeey oai?eo ia ae?aaao I oa II oei?a ?
a?oa??aeueio a?ia?oaic?th ??ciiai aaiaco. Iieacaia ?ioi?iaoeai?noue
ooieoe?iiaeueieo i?ia ?c ci?iith iieiaeaiiy o?ea a ioe?ioe? ?aaeoeaiino?
na?oeaai-noaeeiii? nenoaie oa aeiaaaeaia aeioe?euei?noue aeeth/aiiy
ianeaii? i?oinoaoe/ii? oa aioei?oinoaoe/ii? i?ia a eiiieaen ianoaaeaiiy
oai?eo ia ae?aaao, iniaeeai ia oe? a?oa??aeueii? a?ia?oaic??.

Noi?nia canoinoaaiiy aino?iai oa?iaeieia?/iiai oanoo, ianeaii?
i?oinoaoe/ii? oa aioei?oinoaoe/ii? i?ia aeicaieeei, ii?yae c aea/aiiyi
aaiiaeeiai?/ieo aniaeo?a ae?? aioea?ia?oaiceaieo i?aia?ao?a eaiioaio ?
aaeaa?cooaio, ioe?ieoe ?o aieea ia noaeeiio ?aaeoeai?noue ?
eiiiainaoi?ii-i?enoinoaaeuei? ?aaeoe?? na?oeaai-noaeeiii? nenoaie o
oai?eo c ??cieie oeiaie ae?aaaoo ? a?oa??aeueii? a?ia?oaic??.

Aeyaeai? iniaeeaino? aaiiaeeiai?/ii? a?aeiia?ae? ia iaeii?aciaee i?eeii
aeacaieo i?aia?ao?a o oai?eo ia oeoe?iaee ae?aaao I oa II oei?a c
a?ia?oaiceaiei neiae?iiii ??ciiai iioiaeaeaiiy iiaeooue aooe
canoiniaai? aeey aeeoa?aioe?eiaaiiai aeiai?o a?iioaiceaii? oa?ai?? o
aeaii? eaoaai??? oai?eo.

?acoeueoaoe aeine?aeaeaiue ao?eaii a i?aeoeeo ?iaioe
aiaeie?eiieia?/iiai ? ea?ae?ieia?/iiai a?aeae?eaiue i?nueei? ee?i?/ii?
e?ea?i? ? 9, oa?aiaaoe/iiai a?aeae?eaiiy i?nueei? ee?i?/ii? e?ea?i? ? 6
i.Aei?i?iiao?ianueea. Iaoa??aee ?iaioe aeei?enoiaothoueny a iaa/aeueiiio
i?ioean? eaoaae?e oaeoeueoaonueei? oa?ai?? oa aiaeie?eiieia??
Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii? aeaaeai??.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii ia?niiaeueii i?iaiae?ciaaia
iaoeiaa e?oa?aoo?a c aea?aii? oaiaoeee, i?iaaaeaiee ?ioi?iaoe?eiee
iiooe. Aeanii?o/ii i?iaaaeaii ianoaaeaiiy oai?eo ca?aeii c i?ia?aiith
aeine?aeaeaiiy. ?icoeo?iaea aeaieo ooieoe?iiaeueieo aeine?aeaeaiue, ?o
ia?aeiia ia?iaea, oi?ioaaiiy a?oi ? noaoenoe/ia ia?iaea ?acoeueoao?a
aeine?aeaeaiue ia ia?niiaeueiiio eiii’thoa?? i?iaaaeai? aaoi?ii
ia?niiaeueii. Naiino?eii iaienaii iaeyae e?oa?aoo?e, i?iaaaeaii aiae?c
io?eiaieo ?acoeueoao?a, noi?ioeueiaaii aeniiaee ? i?aeoe/i?
?aeiiaiaeaoe??, ui aeieeaathoue c ?acoeueoao?a aeaiiai aeine?aeaeaiiy.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aoee i?aaenoaaeai? ia IV c’?cae? ea?ae?ieia?a Oe?a?ie
(Aei?i?iiao?ianuee, 1993), OVI iaeani?e iaoeiai-i?aeoe/i?e eiioa?aioe??
c no/anieo ieoaiue ee?i?/ii? aiaeie?eiieia?? (A?iieoey, 1993), ia
iaoeiai-i?aeoe/ieo eiioa?aioe?yo «Aeeaaao — i?iaeaia iaua/aeiaa/aneay»
(Aei?i?iiao?ianuee, 1997, 1998, 1999), V ?in?enueeiio iaoe?iiaeueiiio
eiia?an? «*aeiaae e eaea?noai» (Iineaa, 1998), iaoeiaeo nan?yo
Aei?i?iiao?ianueeiai iaaee/iiai ?inoeoooo a 1993 — 1994 ?.?. Ai?iaaoe?y
aeena?oaoe?? a?aeaoeany 13 ea?oiy 1999 ?. ia ?icoe?aiiio can?aeaii?
eaoaae?e oaeoeueoaonueei? oa?ai?? oa aiaeie?eiieia?? Aei?i?iiao?ianueei?
aea?aeaaii? iaaee/ii? aeaaeai??.

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 11 iaoeiaeo ?ia?o (4 c
ieo — a oeaio?aeueieo aeo?iaeao). 8 ?ia?o i?aeaioiaeai? a ni?aaaoi?noa?,
3 — naiino?eii.

Ianya ? no?oeoo?a ?iaioe. Aeena?oaoe?y aeeeaaeaia ia 162 noi??ieao,
neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, 4 ?icae?e?a aeanieo
aeine?aeaeaiue, iaaiai?aiiy io?eiaieo ?acoeueoao?a, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e. ?iaioa ?ethno?iaaia 34 oaaeeoeyie, ui
noaiiaeoue 25 noi??iie. A?ae?ia?ao?y i?noeoue 196 ?ia?o ee?eeeoeath ? 71
— eaoeiith, ui neeaaea? 27 noi??iie.

INIIAIA *ANOEIA

Ee?i?/ia oa?aeoa?enoeea oai?eo. Ianoaaeaii 166 oai?eo ia oeoe?iaee
ae?aaao a?eii a?ae 17 aei 65 ?ie?a, eio?? ciaoiaeeeeny ia e?eoaaii? a
aiaeie?eiieia?/iiio a?aeae?eaii? 9 i?nueei? ee?i?/ii? e?ea?i? i.
Aei?i?iiao?ianueea. C ieo 117 oai?eo ia ?inoe?icaeaaeiee oeoe?iaee
ae?aaao, 49 oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao. Na?aae
oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao o 39 in?a ia a?aei?/aeinue
i?aeaeuaiiy a?oa??aeueiiai oeneo i? a aiaiiac?, i? ca ia??iae e?eoaaiiy
a noaoe?iia?? (na?aaei?e a?e a a?oi? 37,2 ± 1,8 ?ie?a, na?aaeiy
o?eaae?noue ae?aaaoo — 11,46 ± 1,23 ?ie?a, na?aaei?e ??aaiue
nenoie?/iiai a?oa??aeueiiai oeneo 124,9 ± 2,01 ii ?o.no.,
ae?anoie?/iiai a?oa??aeueiiai oeneo — 80,64 ± 1,2 ii ?o.no.), o 25 in?a
ae?aaiinoiaaia a?ia?oii?/ia oai?iaa II noaae?? (na?aaei?e a?e 50,44 ±
1,5 ?ie?a, na?aaeiy o?eaae?noue ae?aaaoo — 17,04 ± 1,22 ?ie?a, na?aaeiy
o?eaae?noue a?oa??aeueii? a?ia?oaic?? — 13,32 ± 3,45 ?iee, na?aaei?e
??aaiue nenoie?/iiai a?oa??aeueiiai oeneo — 169,54 ( 3,09 ii ?o.no,
ae?anoie?/iiai — 96,08 ( 0,77 ii ?o.no.), o 53 in?a ae?aaiinoiaaia
neiioiiaoe/ia a?oa??aeueia a?ia?oaic?y aiane?aeie ae?aaaoe/ii?
iao?iiao?? (na?aaei?e a?e 40,39 ± 1,80 ?ie?a, na?aaeiy o?eaae?noue
oeoe?iaiai ae?aaaoo — 16,32 ± 1,00 ??e, na?aaeiy o?eaae?noue a?ia?oaic??
— 8,78 ± 2,23 ?ie?a, na?aaei?e ??aaiue nenoie?/iiai a?oa??aeueiiai oeneo
— 164,82 ± 3,2 ii ?o.no, na?aaei?e ??aaiue ae?anoie?/iiai oeneo —
96,04 ± 1,28 ii.?o.no.). Na?aae oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee
ae?aaao o 15 in?a i?aeaeuai? oeeo?e a?oa??aeueiiai oeneo ia
?a?no?oaaeenue (na?aaei?e a?e — 55,43 ± 2,84 ?iee, na?aaeiy o?eaae?noue
ae?aaaoo — 11,29 ± 1,99 ?ie?a, na?aaei?e ??aaiue nenoie?/iiai
a?oa??aeueiiai oeneo — 131,71 ± 3,3 ii ?o.no. ? ae?anoie?/iiai — 79,43
± 2,47 ii ?o. no), o 34 in?a ae?aaiinoiaaia a?ia?oii?/ia oai?iaa II
noaae?? (na?aaei?e a?e — 55,32 ± 0,90 ?ie?a, na?aaeiy o?eaae?noue
oeoe?iaiai ae?aaaoo — 12,38 ±

Ia?aeiia aeine?aeaeaiiy oeaio?aeueii? aaiiaeeiai?ee i?iaiaeeeiny a
ia?o? 2 — 3 aeiae ia?aaoaaiiy oai?iai a noaoe?iia??, i?ney
iiia?aaeiueiai ianoaaeaiiy ? aeeeth/aiiy aioea?ia?oaiceaieo cania?a. A
oie aea aeaiue i?iaiaeeeinue iiaoi?ia ianoaaeaiiy a oiiaao aino?iai
oa?iaeieia?/iiai oanoo /a?ac 1,5 — 2 aiaeeie i?ney i?eeiio eaiioaio
(o??ia «A??noieue Iae??n», NOA) a aeic? 25 ia aai aaeaa?cooaio (o??ia
«AVD», Aa?iai?y) a aeic? 1 ia.

?acoeueoaoe ?iaioe aoee ia?iaeai? ca caaaeueiii?eeiyoeie iaoiaeeeaie
aa??aoe?eii? noaoenoeee (Ia?eia A.I., 1969; Eaaiia TH.E., Iiai?aethe
I.I., 1990) ca aeiiiiiaith aeaeo?iiieo oaaeeoeue «Microsoft Excel — 7.0»
c aeei?enoaiiyi ia?niiaeueiiai eiii’thoa?a IAII IBM 486.

?ACOEUeOAOE AeINE?AeAEAIIss, ?O AIAE?C OA IAAIAI?AIIss

Aea/aiiy iieaciee?a aaiiaeeiai?ee o oai?eo ia oeoe?iaee ae?aaao
aeicaieeei anoaiiaeoe iaai? caeiiii??i? ii?ooaiiy nei?i/oaaeueii?
ooieoe?? na?oey, ia?eoa?e/iiai iii?o noaeei, aia?aaoe/ieo aeo?ao
i?iea?aea caeaaeii a?ae oeio ae?aaaoo ? iayaiino? a?oa??aeueii?
a?ia?oaic??.

Aiae?c iieaciee?a ia’?iiiai e?iaioieo (OI, OIE, O?, N?) aeyaea
cieaeaiiy ?o cia/aiue o an?o oai?eo a ii??aiyii? c eiio?ieai (? < 0,01). A?eueo cia/ia ciaioaiiy oeeo iieaciee?a na?aae oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao a?aei?/a?oueny a a?oi? oai?eo ia a?ia?oii?/io oai?iao: OI - 62,81 ± 4,26 ie, OIE - 4,66 ± 0,31 e/oa. Ca iieacieeaie OIE ? N? oey a?oia a??ia?aeii a?ae??ciyeany a?ae a?oi oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao aac a?ia?oaic?? ? a niieo/aii? c neiioiiaoe/iith a?oa??aeueiith a?ia?oaic??th. Ua a?eueo? a?aei?iiino? iieaciee?a ia'?iiiai e?iaioieo aeyaeaii o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao. Aiie a??ia?aeii a?ae??ciyeeny ia o?eueee a?ae a?oie eiio?ieth, aea e a?ae a?oi oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao, neeaaeath/e aeey OI - 49,85 ± 4,14 ie a a?oi? aac a?ia?oaic?? oa 52,47 ± 2,65 ie a a?oi? c a?ia?oii?/iith oai?iaith, aeey OIE: 3,64 ± 0,29 e/oa a a?oi? aac a?oa??aeueii? a?ia?oaic?? oa 3,93 ± 0,20 e/oa a a?oi? c a?ia?oii?/iith oai?iaith (? < 0,05). Aiaeia?/i? ci?ie aoee anoaiiaeai? ? aeey iieaciee?a oaeaeeino? ?ooo e?ia?: aiie aeyaeeenue i?i?iaeueieie o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao, a??ia?aeii a?ae??ciyth/enue ye a?ae eiio?ieth, oae ? a?ae iieaciee?a IOA oa EO?E a a?oiao oai?eo ia ?inoe?icaeaaeiee ae?aaao (? < 0,05). A??ia?aeii aeu? cia/aiiy ia?eoa?e/iiai noaeeiiiai iii?o a ii??aiyii? c eiio?ieai aeyaeai? o an?o oai?eo (? < 0,001). I?e oeueiio a?eueo cia/i? a?aei?iiino? anoaiiaeaii o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao a ii??aiyii? c oai?eie ia ?inoe?icaeaaeiee ae?aaao. A oie aea /an ca iieacieeii CINI aeyaeaii ae?aaeai? a?aei?iiino? i?ae a?oiaie c ii?iaeueiei oa i?aeaeuaiei a?oa??aeueiei oeneii. Na?aae oai?eo ia oeoe?iaee ae?aaao ? oeio iieaciee CINI a a?oi? oai?eo c ii?iaeueiei a?oa??aeueiei oeneii noaiiaea 1477,29 ± 67,74 ae?i·n-1·ni-5, a a?oi? oai?eo ia a?ia?oii?/io oai?iao - 2302,18 ± 159,88 ae?i·n-1·ni-5, a a?oi? oai?eo ia neiioiiaoe/io a?ia?oaic?th - 1797,98 ± 80,19 ae?i·n-1·ni-5 (? < 0,01). A a?oi? oai?eo ia oeoe?iaee ae?aaao ?? oeio c ii?iaeueiei a?oa??aeueiei oeneii iieaciee CINI noaiiaea 2232,73 ± 194,23 ae?i·n-1·ni-5, a a a?oi? oai?eo ia a?ia?oii?/io oai?iao - iaaaaaoi a?eueoa - 2706,36 ± 139,69 ae?i·n-1·ni-5 (0,05< ? < 0,10). Aiaeii/an a?oie oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao c ii?iaeueiei oa i?aeaeuaiei a?oa??aeueiei oeneii a??ia?aeii ??cieeenue ii iieacieeo III, eio?ee noaiiaea a?aeiia?aeii 49,74 ± 4,56 ? 63,26 ± 3,42 ae?i·n-1·ni-5/i2 (?< 0,05). O oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao c a?oa??aeueiith a?ia?oaic??th ??ciiai aaiaco aeyaeaii a?aei?ii? ni?aa?aeiioaiiy i?ia?aeieo aaiiaeeiai?/ieo iieaciee?a: o oai?eo c a?ia?oii?/iith oai?iaith a?eueo iecuee? cia/aiiy OI ? OIE oa a?eueo aenie? - CINI ? III, a o oai?eo, ui no?aaeaeathoue ia neiioiiaoe/io a?oa??aeueio a?ia?oaic?th, iaaiaee, a?aei?/athoueny aeineoue aenie? iieacieee ia'?iiiai e?iaioieo ia oe? iii??ii i?aeaeuaiiai ia?eoa?e/iiai noaeeiiiai iii?o. Aeyaeai? iniaeeaino? iiaeia iiynieoe a?aei?iiinoyie a iaoiaaiac? a?ia?oii?/ii? oai?iae ? neiioiiaoe/ii? (iao?iaaiii?) a?oa??aeueii? a?ia?oaic??. Aiae?c iieaciee?a nei?i/oaaiino? i?iea?aea iieacaa a??ia?aeia cieaeaiiy o oai?eo ia oeoe?iaee ae?aaao o ii??aiyii? c eiio?ieai o?eueee ?iaeaeno nei?i/oaaiino? i?iea?aea (?NI) (? < 0,02). I?e oeueiio a?eueo cia/ia eiai ciaioaiiy aeyaeeiny o oai?eo ia ?inoe?iiacaeaaeiee ae?aaao. O oai?eo ia oeoe?iaee ae?aaao ? oeio c ii?iaeueiei a?oa??aeueiei oeneii iieaciee ?NI aei??aithaaa 12,14 ± 0,64 i.i., o oai?eo ia a?ia?oii?/io oai?iao - 11,44 ± 0,76 i.i., o oai?eo ia neiioiiaoe/io a?ia?oaic?th - 10,25 ± 0,53 i.i., a oie /an, ye o oai?eo ia oeoe?iaee ae?aaao II oeio aac a?oa??aeueii? a?ia?oaic?? cia/aiiy ?NI noaiiaeei 8,23 ± 0,73 i.i., a o oai?eo c a?ia?oii?/iith oai?iaith - 8,95 ± 0,72 i.i. Ne?ae a?aei?oeoe o an?o oai?eo ia oeoe?iaee ae?aaao a??ia?aeia i?aeaeuaiiy aia?aaoe/ieo aeo?ao i?iea?aea ? ?iaioe na?oey a ii??aiyii? c eiio?ieai (? < 0,001), a oaeiae a??ia?aei? a?aei?iiino? ca oeeie iieacieeaie i?ae a?oiaie c a?oa??aeueiith a?ia?oaic??th ? c ii?iaeueiei a?oa??aeueiei oeneii. sseui a a?oi? oai?eo aac a?oa??aeueii? a?ia?oaic?? c ae?aaaoii I oeio iieaciee CA noaiiaea 12,69 ± 0,17 ao/e, o oai?eo c ae?aaaoii II oeio - 12,88 ± 0,28 ao/e, oi na?aae oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao a a?oi? c a?ia?oii?/iith oai?iaith a?i aei??aithaaa 16,04 ± 0,18 ao/e, c neiioiiaoe/iith a?oa??aeueiith a?ia?oaic??th - 15,82 ± 0,21 ao/e oa o oai?eo ia ?inoe?iiacaeaaeiee ae?aaao ? a?ia?oii?/io oai?iao - 16,31 ± 0,21 ao/e (? < 0,001). Aiae?c iieacieea ?iaeaeno aei?noeino? i?iea?aea (?AEI) iieacaa, ui o oai?eo ia oeoe?iaee ae?aaao a?aei?/a?oueny iia??oaiiy ae?anoie?/iiai ?icneaaeaiiy i?iea?aea, i?i ui na?ae/eoue cieaeaiiy ?AEI o an?o oai?eo a ii??aiyii? c eiio?ieai (? < 0,05). I?e oeueiio ??cieoey i?ae a?oiaie oai?eo aeyaeeanue iaa??ia?aeiith, ca aeeeth/aiiyi a?oie oai?eo ia ae?aaao I oeio ? neiioiiaoe/io a?ia?oaic?th, a ye?e ?AEI aeyaeany i?i?iaeueiei ? a??ia?aeii a?ae??ciyany a?ae iieacieea ?AEI a ?ioeo a?oiao. O oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao c ii?iaeueiei a?oa??aeueiei oeneii cia/aiiy ?AEI noaiiaeei 1,006 ± 0,037 i.i., c a?ia?oii?/iith oai?iaith - 0,931 ± 0,047 i.i., Iiae?aiei /eiii i?iyeeny oaeaee?ni? iieacieee, iieacieee iiooaeiino? na?oey oa ?iaeaen nei?i/oaaiino? i?iea?aea, o?eueee a a?oi? oai?eo ia ae?aaao I oeio ? neiioiiaoe/io a?ia?oaic?th aeeiai?ea ?NI oaeoe/ii aoea a?aenooiy. A?eueo iii?oi? a?aei?iiino? noinothoueny eieeaaiue a i?oinoac? iieaciee?a CINI ? CA. sseui a a?oi? oai?eo ia oeoe?iaee ae?aaao ? oeio c ii?iaeueiei a?oa??aeueiei oeneii eiino?eeoeaia noaeeiia ?aaeoe?y aoea ae?aaeaia iaioa, i?ae o a?oi? caei?iaeo, aea ana ae iaea oo ae ni?yiiaai?noue, oi o oai?eo c a?oa??aeueiith a?ia?oaic??th aiia aoea a?aenooiy. Aei oiai ae a a?oiao oai?eo c i?aeaeuaiei a?oa??aeueiei oeneii a?aei?/aeinue nooo?aa ciaioaiiy iieaciee?a aia?aaoe/ieo cao?ao i?iea?aea (? < 0,05), a o a?oi? oai?eo aac a?ia?oaic?? aeeiai?ea oeeo iieaciee?a aoea iacia/iith. Aeeiai?ea ?AEI o oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao iaei a?ae??ciyeanue a?ae a?oie caei?iaeo, iacaeaaeii a?ae ??aiy a?oa??aeueiiai oeneo. O oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao ci?ie aaiiaeeiai?/ieo iieaciee?a a i?oinoac? o ii??aiyii? c ai?eciioaeueiei iieiaeaiiyi ua a?eueoith i??ith a?ae??ciyeenue a?ae a?oie caei?iaeo. Aeeiai?ea iieaciee?a na?oeaaiai aeooiaoo, oaeaeeino? ?ooo e?ia?, caaaeueiiai noaeeiiiai iii?o, ?iaeaeno nei?i/oaaiino? i?iea?aeo aoea ae?aaeaia ua iaioa, i?ae i?e ae?aaao? I oeio, iniaeeai a a?oi? c ii?iaeueiei a?oa??aeueiei oeneii. Iai?aaeai?noue ci?i CINI a a?oi? oai?eo ia oeoe?iaee ae?aaao ?? oeio c ii?iaeueiei a?oa??aeueiei oeneii aoea oaeith ae, ui ? a aiaeia?/i?e a?oi? oai?eo ia ae?aaao I oeio, oiaoi a?aei?/aeanue neaaei ae?aaeaia eiino?eeoeaia eiiiainaoi?ia ?aaeoe?y, a o oai?eo c a?ia?oii?/iith oai?iaith aeyaeeanue ia?aaeienaeueia ?aaeoe?y ciaioaiiy oiiono ia?eoa?e/ieo noaeei. ?aaeoe?y ?AEI a i?oinoac? o oai?eo ia ?inoe?iiacaeaaeiee ae?aaao aoea oaeith ae iacia/iith, ui e o oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao oa a a?oi? caei?iaeo. Ioe?ithth/e a oe?eiio ci?ie ia?aiao??a e?iaiia?ao o oai?eo ia oeoe?iaee ae?aaao iaio oei?a i?e aeeiiaii? ianeaii? i?oinoaoe/ii? i?iae, ne?ae a?aei?oeoe iaai? iniaeeaino? oa?aeoa?o ?aaeoeaiino? na?oeaai-noaeeiii? nenoaie, iia'ycai? c oeiii ae?aaaoo ? iayai?noth a?oa??aeueii? a?ia?oaic??. Aeey oai?eo ia iai?oanoiee oeoe?iaee ae?aaao, c iii??ieie oa ae?aaeaieie i?iyaaie ae?aaaoe/ieo aia?iiao?e, iayai?noth ae?aaaoe/ii? ia?eoa?e/ii? iie?iae?iiao?? i?eoaiaii? ci?ie ?aaeoeaiino? na?oeaai-noaeeiii? nenoaie a a?e ciaioaiiy ?aaeoe?? nei?i/oaaeueii? ooieoe?? i?iea?aea oa cieaeaiiy eiino?eeoeaii? ooieoe?? noaeei. Oe? ?acoeueoaoe i?aeoaa?aeaeothoueny e?oa?aoo?ieie aeaieie (Ia?oeei?e ?.I., 1994). A?eueo ae?aaeai? ci?ie i?eoaiaii? oai?ei ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao aiane?aeie iayaiino? ae?aaeaieo i?e?iaia?iiao?e ? ii/aoeiaeo aai iii??ieo aeya?a aoa?ineea?ico noaeei, a oaeiae o?aaeaiiy i?iea?aea (ae?aaaoe/ia ea?ae?iiao?y ? neea?ioe/i? ci?ie i?iea?aea). I?e iaio oeiao oeoe?iaiai ae?aaaoo ne?ae a?aecia/eoe ??cieoeth a aeeiai?oe? ia?eoa?e/iiai iii?o ? aia?aaoe/ieo cao?ao i?iea?aea caeaaeii a?ae iayaiino? a?ia?oaic??: i?e ii?iaeueiiio a?oa??aeueiiio oeneo caa??aa?oueny neaaea eiino?eeoeaia i?enoinoaaeueia ?aaeoe?y ia i?oinoac ? oaeoe/ii ia i?iythoueny aia?aaoe/i? cao?aoe i?iea?aea, a oie /an ye i?e iayaiino? a?oa??aeueii? a?ia?oaic?? noaeeiia ?aaeoeai?noue ??cei cieaeaia, ui aeyaey?oueny o a?aenooiino? ci?i CINI /e eiai ia?aaeienaeueiiio ciaioaii? ia oii? cieaeaiiy aia?aaoe/ieo cao?ao. I?e aioei?oinoaoe/iiio aei?iaoaaii? a?aeaoaa?oueny ca?eueoaiiy iaaaioaaeaiiy ia'?iii, ui ciaoiaeeoue nai? a?aeia?aaeaiiy a oaeeo o?c?ieia?/ieo ?aaeoe?yo na?oeaai-noaeeiii? nenoaie, ye i?aeaeuaiiy iieaciee?a ia'?iiiai e?iaioieo, a oaeiae iiooaeiino? na?oey, c iaeii/aniei ciaioaiiyi ia?eoa?e/iiai iii?o noaeei ye eiiiainaoi?ii? noaeeiii? ?aaeoe?? aeey i?aeo?eiee nenoaiiiai ? i?aaiiiai (iiceiaiai ? ea?ae?aeueiiai) e?iaioieo ia iioeiaeueiiio ??ai?. Iiae?aia ?aaeoe?y a iaoiio aeine?aeaeaii? aoea aeyaeaia a a?oi? eiio?ieth, aea aeeiai?ea CINI (ciaioaiiy ia 13%) ? OIE (ca?eueoaiiy ia 19%) o ii??aiyii? c ai?eciioaeueiei iieiaeaiiyi (? < 0,05) aoea ae?aaeaia i?eaeecii iaeiaeiaith i??ith, aea iineea ??ciini?yiiaaiee oa?aeoa?. A oie aea /an niinoa??aaeiny i?aeaeuaiiy aaiiaeeiai?/ii? iiooaeiino? na?oey, iiooaeiino? e?aiai oeoii/ea (? < 0,01), iacia/i? i?aeaeuaiiy ?NI ? cieaeaiiy ?AEI aiane?aeie oneeaaeiaiue ei?iia?iiai e?iaioieo a oiiaao ca?eueoaiiai e?iaioieo. CA oaeoe/ii ia ci?ithaaeenue a ca'yceo c a?aenooi?noth ae?aaeaii? aeeiai?ee a?oa??aeueiiai oeneo. A oie aea /an o oai?eo ia oeoe?iaee ae?aaao anoaiiaeaii cia/ia ca?eueoaiiy iieaciee?a OIE oa OI, a oaeiae AIN, a?eueo ae?aaeaia o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao (? < 0,05). Iacaaaeath/e ia ca?eueoaiiy ia'?iieo iieaciee?a, o a?eueoino? oai?eo a?aeiia?aeia cieaeaiiy CINI aoei ae?aaeaia a iaio?e i???, oiaoi eiiiainaoi?ia noaeeiia ?aaeoe?y aoea iineaaeaia. Iniaeeai iii?oiith oey iaa?aeiia?aei?noue aeyaeeanue a iaio a?oiao oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao, a oaeiae o oai?eo ia ?inoe?icaeaaeiee ae?aaao c i?aeaeuaiei ??aiai a?oa??aeueiiai oeneo. Cia/ieo a?aei?iiinoae oeeo ci?i o oai?eo ia ae?aaao I oeio c a?ia?oii?/iith oai?iaith ? neiioiiaoe/iith a?oa??aeueiith a?ia?oaic??th ie ia aeyaeee. A oie aea /an ne?ae a?aecia/eoe iaioee i?e??no ?NI o a?aeiia?aeue ia i?aeaeuaiiy OI ? OIE o an?o oai?eo c a?ia?oaiceaiei neiae?iiii. Iiae?aia ?aaeoe?y aoea a?eueo oa?aeoa?ia aeey oai?eo ia a?ia?oii?/io oai?iao, iniaeeai i?e I oei? oeoe?iaiai ae?aaaoo. Aiaeii/an i?e iayaiino? a?ia?oaiceaiiai neiae?iio niinoa??aaeinue a??ia?aeia cieaeaiiy ?AEI, ui ciaeoei nai? a?aeia?aaeaiiy iaeiaeiaith i??ith i?e iaio oeiao ae?aaaoo, iacaeaaeii a?ae aaiaca a?ia?oaic??. Iiae?ai? ?aaeoe?? iiaeia ?icoe?ithaaoe ye cieaeaiiy i?enoinoaaeueieo ?aaeoe?e i?iea?aea aiane?aeie neeaaeiiai o?aaeaiiy na?oey i?e oeoe?iaiio ae?aaao?, iayaiino? a?ia?o?io?? i?iea?aea e?aiai oeoii/ea ? ae?aaaoe/ii? ea?ae?iiao??. Oaeei /eiii, ianeaia i?oi- oa aioei?oinoaoe/ia i?iae aeicaieythoue io?eiaoe aeiaeaoeiao aaaeeeao ?ioi?iaoe?th i?i ooieoe?iiaeueiee noai na?oeaai-noaeeiii? nenoaie, nooi?iue ?aaeoeaiino? noaeeiiiai eiiiiiaioa oa i?iea?aea i?e oeoe?iaiio ae?aaao?, iniaeeai i?e iayaiino? a?oa??aeueii? a?ia?oaic??. Iaeii?aciaee i?eeii eaiioaio oa aaeaa?cooaio o oai?eo ia oeoe?iaee ae?aaao ? a?oa??aeueio a?ia?oaic?th noi?iaiaeaeoaaany aeinoaoi?i a?iioaiceaiei aoaeoii (? < 0,001), a?eueo ae?aaeaiei ia aaeeaaiiy eaiioaio a a?oi? oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao oa a?ia?oii?/io oai?iao, a ia i?eeii aaeaa?cooaio - o oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao oa neiioiiaoe/io a?oa??aeueio a?ia?oaic?th, a oaeiae o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao ? a?ia?oii?/io oai?iao. O a?eueoino? oai?eo a?aecia/aeanue aeia?a ia?aiinei?noue ia?oi? aeice i?aia?aoo aac ae?aaeaieo yaeu i?oinoaoe/ii? a?iioii??. A a?oi? oai?eo ia ?inoe?icaeaaeiee ae?aaao oa a?ia?oii?/io oai?iao a?iioaiceaiee aoaeo eaiioaio aoa iaoiiaeaiee ae?aaeaiei cieaeaiiyi ia?eoa?e/iiai iii?o (? < 0,01), i?e oeueiio a?aei?/aeinue ca?eueoaiiy iieaciee?a OI oa OIE, ?AEI, cieaeaiiy cao?ao aia?a?? ? ?iaioe na?oey. A oie aea /an o oai?eo c neiioiiaoe/iith a?oa??aeueiith a?ia?oaic??th AENIIAEE 1. O oai?eo ia oeoe?iaee ae?aaao iathoue i?noea ii?ooaiiy ooieoe?iiaeueiiai noaio na?oeaai-noaeeiii? nenoaie, eio?? i?iyaeythoueny o cieaeaii? na?oeaaiai aeooiaoo, nei?i/oaaeueii? caeaoiino? i?iea?aea, i?aeaeuaii? ia?eoa?e/iiai iii?o noaeei ? aia?aaoe/ieo cao?ao na?oey, a iia??oaii? ae?anoie?/iie ooieoe?? i?iea?aea, a oaeiae a ii?ooaii? ?aaeoeaiino? na?oey ? noaeei i?e i?iaaaeaii? i?oi- ? aioei?oinoaoe/ieo i?ia. Iniaeeai cia/i? ci?ie aeyaeaii o oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao. 2. I?e ??cieo aa??aioao a?oa??aeueii? a?ia?oaic?? o oai?eo ia oeoe?iaee ae?aaao I oeio ?niothoue nooo?a? a?aei?iiino? o aaiiaeeiai?/iiio noaoon?. Aeey oai?eo ia a?ia?oii?/io oai?iao oa?aeoa?ii cieaeaiiy ia'?iieo iieaciee?a, nooo?aa i?aeaeuaiiy ia?eoa?e/iiai iii?o, o a?eueoino? oai?eo (60 %) aeyaey?oueny a?iie?iaoe/iee oei e?iaiia?ao. Iniaeea?noth neiioiiaoe/ii? a?oa??aeueii? a?ia?oaic?? ? iii??ia i?aeaeuaiiy noaeeiiiai iii?o i?e caa?aaeaiiio ia'?iiiio e?iaioieo, iia??oaiiy ae?anoie?/ii? ooieoe?? i?iea?aea, iayai?noue o a?eueoino? oai?eo a?ia?- (48,9 %) oa aoe?iaoe/iiai (22,2 %) oei?a e?iaiia?ao. 3. Oai?ei ia oeoe?iaee ae?aaao i?eoaiaiia cieaeaiiy i?enoinoaaeueieo iiaeeeainoae na?oeaai-noaeeiii? nenoaie. Ca aeaieie ianeaii? i?oinoaoe/ii? i?iae i?i oea na?ae/aoue iineaaeaiiy eiino?eeoeaii? ?aaeoe?? noaeei oa iaaaeaeaaoi?noue ciaioaiiy na?oeaaiai aeooiaoo, a ca aeaieie aioei?oinoaoe/ii? i?iae - iaaeinoaoi?noue aaciaeeeaoaoi?ii? ?aaeoe?? oa iia??oaiiy ae?anoie?/iiai ?icneaaeaiiy i?iea?aea. 4. Aaiiaeeiai?/i? ci?ie o a?aeiia?aeue ia i?oinoaoe/iee aieea a a?eueo?e i??? iia'ycai? c iayai?noth a?ia?oaiceaiiai neiae?iio, i?ae c oeiii oeoe?iaiai ae?aaaoo, ui a?aeia?aaeo?oueny o oaeoe/i?e a?aenooiino? ci?i ia?eoa?e/iiai noaeeiiiai iii?o oa o cieaeaii? cao?ao aia?a?? na?oey o oai?eo c a?oa??aeueiith a?ia?oaic??th i?e iaio oeiao oeoe?iaiai ae?aaaoo. 5. Ci?ie aaiiaeeiai?ee o a?aeiia?aeue ia aioei?oinoaoe/iee aieea iia'ycai? ye c oeiii oeoe?iaiai ae?aaaoo, oae ? c iayai?noth a?oa??aeueii? a?ia?oaic??. Aeey oai?eo ia ?inoe?iiacaeaaeiee oeoe?iaee ae?aaao oa?aeoa?ia cia/ia i?aeaeuaiiy ia'?iieo iieaciee?a oa aaiiaeeiai?/ii? iiooaeiino? na?oey iacaeaaeii a?ae ??aiy a?oa??aeueiiai oeneo. O oai?eo ia iaeaeaa oeie oeoe?iaiai ae?aaaoo c a?ia?oaiceaiei neiae?iiii, ia? i?noea cieaeaiiy ?iaeaeno aei?noeino? i?iea?aeo iacaeaaeii a?ae aaiaco a?oa??aeueii? a?ia?oaic??. 6. O oai?eo ia a?ia?oii?/io oai?iao oa oeoe?iaee ae?aaao I oa II oei?a a?iioaiceaiee aoaeo eaiioaio iaoiiaeth?oueny cieaeaiiyi caaaeueiiai ia?eoa?e/iiai iii?o, a o oai?eo c neiioiiaoe/iith iao?iaaiiith a?oa??aeueiith a?ia?oaic??th ia oe? ae?aaaoo I oeio - ia?aaaaeiei aieeaii ia ia'?ii? iieacieee e?iaiia?ao. Eaiioai ia ia? iaaaoeaiiai aieeao ia eiiiainaoi?ii - i?enoinoaaeuei? ?aaeoe?? na?oeaai - noaeeiii? nenoaie i?e oeoe?iaiio ae?aaao?. 7. A?iioaiceaiee aoaeo aaeaa?cooaio o oai?eo ia oeoe?iaee ae?aaao noi?iaiaeaeo?oueny iaiaeiicia/ieie ci?iaie ia?eoa?e/iiai iii?o: iaeiae?aaeaiith aeeiai?eith i?e ?inoe?icaeaaeiiio oeoe?iaiio ae?aaao? oa a?eueo cia/iith - i?e ?inoe?iiacaeaaeiiio oeoe?iaiio ae?aaao?, i?e a?aenooiino? nooo?aiai aieeao ia a?eueo?noue aaiiaeeiai?/ieo ia?aiao??a. O oai?eo ia oeoe?iaee ae?aaao aaeaa?cooai caeaoiee iineaaethaaoe noaeeiio ?aaeoeai?noue. I?AEOE*I? ?AEIIAIAeAOe?? 1. Ianeaia i?oinoaoe/ia ? aioei?oinoaoe/ia i?iae iiaeooue aooe ?aeiiaiaeiaai? aeey aeei?enoaiiy a ee?i?/i?e i?aeoeoe? c iaoith ioe?iee ooieoe?iiaeueiiai noaio na?oeaai-noaeeiii? nenoaie o oai?eo ia a?oa??aeueio a?ia?oaic?th ia oe? oeoe?iaiai ae?aaaoo. 2. I?e i?iaaaeaii? iaaaioaaeoaaeueieo i?ia ?c ci?iith iieiaeaiiy o?ea iaea?eueo ?ioi?iaoeaiith ? aeeiai?ea iieaciee?a na?oeaaiai aeooiaoo, ia?eoa?e/iiai noaeeiiiai iii?o, ?iaeaeno nei?i/oaaiino? i?iea?aea. I?e i?iaaaeaii? ianeaii? i?oinoaoe/ii? i?iae ne?ae a?aoiaoaaoe oaeiae iieaciee aia?aaoe/ieo cao?ao, a i?e i?iaaaeaii? aioei?oinoaoe/ii? i?iae - iieaciee aaiiaeeiai?/ii? iiooaeiino? na?oey oa ?iaeaen aei?noeino? i?iea?aeo, yeee aeicaiey? aeyaeoe ?aca?ai? iiaeeeaino? i?iea?aea. 3. A oiiaao niaoe?ae?ciaaieo ea?ae?ieia?/ieo oa aiaeie?eiieia?/ieo a?aeae?eaiue a eiiieaen aeiaeaoeiaiai ianoaaeaiiy oai?eo ia oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th aeioe?eueii aeeth/aoe cai?iiiiiaaiee ooieoe?iiaeueii-oa?iaeieia?/iee oano c iaoith aaeaeaaoiiai i?aeai?o a?iioaiceaii? oa?ai?? oa aeeiai?/iiai eiio?ieth ca ?? aoaeoeai?noth. Noi?nia canoinoaaiiy aino?iai oa?iaeieia?/iiai oanoo ? ooieoe?iiaeueieo i?oi- oa aioei?oinoaoe/ii? i?ia o a?eueoino? (70,8 %) aeiaaee?a aeicaiey? anoaiiaeoe aaiiaeeiai?/iee iaoai?ci ae?? aioea?ia?oaiceaieo i?aia?ao?a oa ioe?ieoe ?o aieea ia eiiiainaoi?ii-i?enoinoaaeuei? ?aaeoe?? nenoaie e?iaiia?ao o oai?eo ia oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th 4. I?e oeoe?iaiio ae?aaao? ca iayaiino? a?ia?oii?/ii? oai?iae ?aeiiaiaeo?oueny aeeoa?aioe?eiaaia i?ecia/aiiy aioea?ia?oaiceaii? oa?ai??: oai?ei ia ?inoe?icaeaaeiee ae?aaao aaaeai?oa i?ecia/aoe eaiioai, a oai?ei ia ?inoe?iiacaeaaeiee ae?aaao - aaeaa?cooai. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. Ia?oeaaa O.I., Oeuaiei I.A., Ia?oeeiie ?.I. Iioi?iaoeaiinoue i?oinoaoe/ii? i?iae oa i?iae c o?ce/iei iaaaioaaeaiiyi i?e aeine?aeaeaii? nei?i/oaaeueii? caeaoiino? i?iea?aea o oai?eo ia oeoe?iaee ae?aaao // Iaaee/i? ia?niaeoeae. - 1997. - O. II, ? 3. - N. 19 - 21. 2. Ia?oeaaa O.A., Ia?oeeiee A.I., Oeuaiei E.A. Aeeaaiinoe/aneia cia/aiea ooieoeeiiaeueiuo i?ia a ioeaiea nie?aoeoaeueiie niiniaiinoe ieiea?aea o aieueiuo naoa?iui aeeaaaoii // E?ea?nueea ni?aaa. - 1997.- ? 4. - N. 114 - 118. 3. Oeuaiei I.A., Ia?oeeiie ?.I. Noai oeaio?aeueii? aaiiaeeiaiiee o oai?eo ia oeoe?iaee ae?aaao c ??cieie oi?iaie a?oa??aeueii? a?ia?oaic?? // Iaaee/i? ia?niaeoeae. - 1999. - O. IV, ? 1. - N. 35 - 38. 4. Oeuaiei ?.A. Aieea naeaeoeaiiai (1-aae?aiiaeieaoi?a aaeaa?cooaio ia iieacieee oeaio?aeueii? aaiiaeeiai?ee o oai?eo ia ?inoe?icaeaaeiee oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th // Iaaee/i? ia?niaeoeae. - 1999. - O. IV, ? 3, /. 1. - N. 28 - 31. 5. Iaaeaeei A.I., Oeuaiei I.A., Oa?aniaa I.E. Noai oeaio?aeueii? aaiiaeeiaiiee o oai?eo ia a?oa??aeueio a?ia?oaic?th i?e iayaiino? oeoe?iaiai ae?aaaoo // Oace aeii. IV c'?caeo ea?ae?ieia?a Oe?a?ie. - Aei?i?iiao?ianuee, 1993. - N. 58. 6. Oeuaiei I.A. Iniaeeaino? oei?a oeaio?aeueii? aaiiaeeiaiiee i?e ??cieo oi?iao a?oa??aeueii? a?ia?oaic?? o oai?eo ia oeoe?iaee ae?aaao // No/ani? ieoaiiy ee?i?/ii? aiaeie?eiieia??: Iaoa??aee XVI iae. iaoe.-i?aeo. eiio., i?enay/aii? 30-?i//th Aiiieoeueeiai iaeaniiai eeiii/iiai aiaeie?eiieia?/iiai aeeniaina?o. - A?iieoey, 1993. - N. 41. 7. Oeuaiei E.A., Ia?oeeiee A.I. Nia?aiaiiua iiaeoiaeu e ea/aieth a?oa?eaeueiie aeia?oaicee o aieueiuo naoa?iui aeeaaaoii // Oac. aeiee. iao/.-i?aeo. eiio. "Aeeaaao - i?iaeaia iaua/aeiaa/aneay". - Aeiai?iiao?iane, 1997. - Aui. 2. - N. 110 - 111. 8. Ia?oeeiee A.I., Oeuaiei E.A. Iniaaiiinoe oeaio?aeueiie aaiiaeeiaieee o aieueiuo einoeeicaaeneiui naoa?iui aeeaaaoii // Oac. aeiee. iao/.-i?aeo. eiio. "Aeeaaao - i?iaeaia iaua/aeiaa/aneay". - Aeiai?iiao?iane, 1997. - Aui. 2. - N. 68 - 70. 9. Oeuaiei E.A., Ia?oeeiee A.I., Oeuaaieiaa I.I. I?eiaiaiea oa?iaeieiae/aneie i?iau aeey i?iaiice?iaaiey eiaeeaeaeoaeueiiai aeiioaiceaiiai yooaeoa eaiioaia o aieueiuo a?oa?eaeueiie aeia?oaiceae ia oiia naoa?iiai aeeaaaoa // V ?in. iaoeeiiaeueiue eiia?ann "*aeiaae e eaea?noai". - I., 1998. - N. 531. 10. Oeuaiei E.A., Oeuaaieiaa I.I., Ianoa?on E.I. Ioeaiea aeiioaiceaiiai e aaiiaeeiaie/aneiai yooaeoia aaeaa?cooaia o aieueiuo naoa?iui aeeaaaoii ia oiia a?oa?eaeueiie aeia?oaicee // Oac. aeiee. iao/.- i?aeo. eiio. "Aeeaaao - i?iaeaia iaua/aeiaa/aneay". - Aeiai?iiao?iane, 1998. - Aui. 3. - N. 155 - 156. 11. Oeuaiei E.A. Aeeaaiinoe/aneea aiciiaeiinoe aioei?oinoaoe/aneie i?iau a ioeaiea ooieoeeiiaeueiiai ninoiyiey na?aea/ii-ninoaeenoie nenoaiu o aieueiuo naoa?iui aeeaaaoii // Oac. aeiee. iao/.- i?aeo. eiio. "Aeeaaao - i?iaeaia iaua/aeiaa/aneay". - Aeiai?iiao?iane, 1999. - Aui. 4. - N. 80 - 82. AIIOAOeIss Oeuaiei I.A. Cia/aiiy ooieoe?iiaeueieo oa oa?iaeieia?/ieo i?ia a ioe?ioe? noaio na?oeaai-noaeeiii? nenoaie o oai?eo ia oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.11 - ea?ae?ieia?y. - Caii??cueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Caii??aeaey, 1999. Aea/aiee noai oeaio?aeueii? aaiiaeeiaiiee o oai?eo ia oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th. Aeyaeaii iniaeeaino? aaiiaeeiaii/iiai noaoono oa ?aaeoeaiino? na?oeaai-noaeeiii? nenoaie o oai?eo ia oeoe?iaee ae?aaao I ? II oei?a, ui no?aaeaeathoue ia a?ia?oii?/io oai?iao oa neiioiiaoe/io a?oa??aeueio a?ia?oaic?th aiane?aeie ae?aaaoe/ii? iao?iiao??. Iieacaia ?ioi?iaoeai?noue ianeaii? i?oinoaoe/ii? oa aioei?oinoaoe/ii? i?ia i?e aeine?aeaeaii? ?aaaoaaiiy nenoaie e?iaiia?ao o a?aeiia?aeue ia iaaaioaaeoaaeuei? oanoe. Anoaiiaeai? iniaeeaino? aaiiaeeiaii/iiai aoaeoo eaiioaio oa aaeaa?cooaio o oai?eo ia oeoe?iaee ae?aaao oa a?oa??aeueio a?ia?oaic?th. Aeyaeaiee aieea oeeo i?aia?ao?a ia na?oeaai-noaeeiio ?aaeoeai?noue i?e oeoe?iaiio ae?aaao?. Aeiaaaeaia aeioe?euei?noue aeei?enoaiiy eiiieaenii? ooieoeiiiaeueii-oa?iaeieiai/ii? i?iae o ee?i?/i?e i?aeoeoe?. Eeth/ia? neiaa: oeaio?aeueia aaiiaeeiai?ea, ea?aeiiaaiiaeeiaiiea, oeoe?iaee ae?aaao, a?oa??aeueia a?ia?oaic?y, ooieoe?iiaeuei? i?iae, eaiioai, aaeaa?cooai. AIIIOAOeEss Oeuaiei E.A. Cia/aiea ooieoeeiiaeueiuo e eaea?noaaiiuo i?ia aeey ioeaiee ninoiyiey na?aea/ii-ninoaeenoie nenoaiu o aieueiuo naoa?iui aeeaaaoii e a?oa?eaeueiie aeia?oaiceae. - ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.11 - ea?aeeieiaey. - Caii?iaeneee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Caii?iaeuea, 1999. Oeaeueth ?aaiou yaeeinue eco/aiea ooieoeeiiaeueiiai ninoiyiey na?aea/ii-ninoaeenoie nenoaiu e ioeaiea aaiiaeeiaie/aneeo yooaeoia eaiioaia e aaeaa?cooaia o aieueiuo naoa?iui aeeaaaoii I e II oeiia, no?aaeathueo a?oa?eaeueiie aeia?oaiceae ?acee/iiai aaiaca. Auei ianeaaeiaaii 166 aieueiuo naoa?iui aeeaaaoii (n?aaeiee aic?ano 44,9 ± 2,3 aiaea). N?aaee 117 aieueiuo einoeeicaaeneiui naoa?iui aeeaaaoii auei 39 /aeiaae n ii?iaeueiui a?oa?eaeueiui aeaaeaieai, 25 aieueiuo, no?aaeathueo aeia?oiie/aneie aieaciueth II noaaeee, 53 aieueiuo, no?aaeathueo neiioiiaoe/aneie (iao?iaaiiie) a?oa?eaeueiie aeia?oaiceae. N?aaee 49 aieueiuo einoeeiiacaaeneiui naoa?iui aeeaaaoii o 15 /aeiaae auei ii?iaeueiia a?oa?eaeueiia aeaaeaiea, o 34 - aeeaaiinoe?iaaia aeia?oiie/aneay aieaciue II noaaeee. Eiio?ieueioth a?oiio ninoaaeee 28 i?aeoe/anee caei?iauo eeoe (n?aaeiee aic?ano 30,2 ± 3,8 aiaea). Oaiaoe/aneia ianeaaeiaaiea aeeth/aei ?aiiieeea?aeeia?aoe/aneia enneaaeiaaiea na?aea/ii-ninoaeenoie nenoaiu a iieia, a oaeaea i?e i?iaaaeaiee ianneaiie i?oinoaoe/aneie e aioei?oinoaoe/aneie i?ia n eniieueciaaieai iiai?ioiiai noiea, iicaieythuaai iiaeieiaoue aieiaiie eiiaoe iiae oaeii 60 a?aaeonia e iioneaoue aai ia 45 a?aaeonia. ?aiiieeea?aeeia?aoe/aneia enneaaeiaaiea aeeth/aei neio?iiioth ?aaeno?aoeeth oao?aiiey?iie a?oaeiie ?aia?aoee, a? ia?aie i?iecaiaeiie, YEA e oiiiea?aeeia?aoee. Ianeaaeiaaiea i?iaiaeeee a ia?aua 2 - 3 aeiy iinooieaiey a noaoeeiia?. Aieueiui n a?oa?eaeueiie aeia?oaiceae i?iaiaeeee iiaoi?iia enneaaeiaaiea /a?ac 1,5 /ana iinea iaeiie?aoiiai i?e?ia 25 ia eaiioaia eee 1 ia aaeaa?cooaia. A ?acoeueoaoa enneaaeiaaiey auee auyaeaiu ia?ooaiey ooieoeeiiaeueiiai ninoiyiey na?aea/ii-ninoaeenoie nenoaiu, i?iyaeythueany a nieaeaiee na?aea/iiai aua?ina, nie?aoeoaeueiie niiniaiinoe ieiea?aea, iiauoaiee ia?eoa?e/aneiai nii?ioeaeaiey ninoaeia, a oaeaea a oooaeoaiee aeeanoiee/aneie ooieoeee ieiea?aea. Au?aaeaiiinoue oeacaiiuo eciaiaiee a aieueoie ia?a iaoneiaeaia oeiii aeeaaaoa: iaeaieaa cia/eoaeueiia iiauoaiea ia?eoa?e/aneiai nii?ioeaeaiey, eae e nieaeaiea na?aea/iiai aua?ina, oa?aeoa?ii aeey einoeeiiacaaeneiiai naoa?iiai aeeaaaoa. Onoaiiaeaii, /oi iaee/ea e oa?aeoa? aeia?oaiceiiiiai neiae?iia yaeythony iaeieie ec aaaeoueo oaeoi?ia, aeeythueie ia ea?aeei-aaiiaeeiaieeo. O aieueiuo naoa?iui aeeaaaoii i?e iiauoaiee o?iaiy a?oa?eaeueiiai aeaaeaiey a aieueoae ia?a iiauoaiu ia?eoa?e/aneia nii?ioeaeaiea, yia?aaoe/aneea cao?aou ieiea?aea e aiaoiyy ?aaioa na?aeoea, /oi aieaa oa?aeoa?ii aeey aeia?oiie/aneie aieacie, /ai aeey neiioiiaoe/aneie aeia?oaicee. Iniaaiiinoyie aeia?oaiceiiiiai neiae?iia aneaaenoaea neiioiiaoe/aneie a?oa?eaeueiie aeia?oaicee, ia?yaeo n iiauoaiiuie iieacaoaeyie ia?eoa?e/aneiai nii?ioeaeaiey, yaeythony aeinoaoi/ii aunieea iieacaoaee oaea?iiai e ieiooiiai iau?iia, a oaeaea cia/eoaeueiia iiauoaiea aeeanoiee/aneie ?eaeaeiinoe ieiea?aea. Iaeaieaa /oanoaeoaeueiuie iieacaoaeyie, io?aaeathueie ooieoeeiiaeueiia ninoiyiea na?aea/ii-ninoaeenoie nenoaiu o aieueiuo naoa?iui aeeaaaoii, iniaaiii i?e iaee/ee a?oa?eaeueiie aeia?oaicee, yaeythony oaea?iue iau?i, ia?eoa?e/aneia nii?ioeaeaiea ninoaeia, ?anoiae yia?aee, eiaeaen nie?aoeiinoe ieiea?aea e eiaeaen ae?noeinoe ieiea?aea. Aiaeec ?acoeueoaoia ianneaiie i?oinoaoe/aneie e aioei?oi-noaoe/aneie i?ia iieacae eo eioi?iaoeaiinoue a ioeaiea ?aaeoeaiinoe na?aea/ii-ninoaeenoie nenoaiu o aieueiuo naoa?iui aeeaaaoii. Onoaiiaeaii nieaeaiea eiiiainaoi?iie ?aaeoeaiinoe aiia?aoa e?iaiia?auaiey i?e naoa?iii aeeaaaoa, iniaaiii o aieueiuo einoeeiiacaaeneiui aeeaaaoii, a oaeaea o aieueiuo a?oa?eaeueiie aeia?oaiceae. I?e yoii i?oinoaoe/aneay i?iaa nii?iaiaeaeaaony ineaaeaieai eiino?eeoeaiie ?aaeoeee ia?eoa?e/aneeo ninoaeia e iaiaa au?aaeaiiie ii n?aaiaieth n eiio?ieueiie a?oiiie noaiaiueth nieaeaiey iieacaoaeae na?aea/iiai aua?ina e iau?iiiai e?iaioiea ia aunioa i?iau. I?e aioei?oinoaoe/aneie i?iaa ioia/aii oiaiueoaiea aaciaeeeaoaoi?iie ?aaeoeee ninoaeia a ioaao ia au?aaeaiioth iaa?oceo iau?iii, oooaeoaiea ?aaeoeee ieiea?aea a aeaea iaaaeaeaaoii iaeiai i?e?inoa eiaeaena nie?aoeiinoe ieiea?aea e iiauoaiey aeeanoiee/aneie ?eaeaeiinoe ieiea?aea. Iaeiie?aoiue i?e?i eaiioaia e aaeaa?cooaia o aieueiuo naoa?iui aeeaaaoii e a?oa?eaeueiie aeia?oaiceae (i?aeiouanoaaiii n aeiieeiaoe/aneei oeiii e?iaiia?auaiey) nii?iaiaeaeaeny aeinoaoi/iui aeiioaiceaiui yooaeoii, aieaa au?aaeaiiui ia i?e?i eaiioaia o aieueiuo einoeeicaaeneiui naoa?iui aeeaaaoii e aeia?oiie/aneie aieaciueth, a ia i?e?i aaeaa?cooaia - o aieueiuo einoeeicaaeneiui naoa?iui aeeaaaoii a ni/aoaiee n neiioiiaoe/aneie a?oa?eaeueiie aeia?oaiceae e o aieueiuo einoeeiiacaaeneiui naoa?iui aeeaaaoii e aeia?oiie/aneie aieaciueth. Auyaeaii, /oi eaiioai ia ieacuaaao io?eoeaoaeueiiai aeeyiey ia i?eniiniaeoaeueiua ?aaeoeee na?aea/ii-ninoaeenoie nenoaiu, a oi a?aiy eae i?e?i aaeaa?cooaia i?eaiaeee e ineaaeaieth eiiiainaoi?ii-i?eniiniaeoaeueiie eiino?eeoeaiie ?aaeoeee ia?eoa?e/aneeo ninoaeia. Onoaiiaeaia iaiaeiicia/iinoue aaiiaeeiaie/aneiai ioaaoa ia iaeiie?aoiue i?e?i eaiioaia e aaeaa?cooaia o aieueiuo ?aciuie oeiaie naoa?iiai aeeaaaoa e a?oa?eaeueiie aeia?oaicee. Iieo/aiiua ?acoeueoaou iicaieytho ?aeiiaiaeiaaoue eniieueciaaiea eiiieaeniie ooieoeeiiaeueii-oa?iaeieiae/aneie i?iau o aieueiuo naoa?iui aeeaaaoii e a?oa?eaeueiie aeia?oaiceae aeey aeiiieieoaeueiie ioeaiee ninoiyiey na?aea/ii-ninoaeenoie nenoaiu e iiaeai?a ia/aeueiie aioeaeia?oaiceaiie iiiioa?aiee. Eeth/aaua neiaa: oeaio?aeueiay aaiiaeeiaieea, ea?aeeiaaiiaeeiaieea, naoa?iue aeeaaao, a?oa?eaeueiay aeia?oaicey, ooieoeeiiaeueiua i?iau, eaiioai, aaeaa?cooai. SUMMARY Tischenko I.V. The importance of functional and pharmacologic tests in estimation of cardio-vascular system state in patients with both diabetes mellitus and Arterial Hypertension. - Manuscript. The Thesis for the scientific degree of candidate of medical sciences in speciality 14.01.11 - cardiology. - Zaporozhye state medical university, Zaporozhye, 1999. The state of central hemodinamics was learned in patients with both diabetes mellitus and arterial hypertension. Peculiarities of hemodinamic state and reactivity of cardio-vascular system in patients with I and II types of diabetes and essential hypertension and symptomatic arterial hypertension due to diabetic nephropathy were revealed. The information of passive orthostatic and antiorthostatic tests for investigation of blood circulation system reaction in the time of load tests was shown. Peculiarities of capoten and adverzutene hemodinamic effects in diabetic hypertensive patients were determined. The influence of capoten and adverzutene for the vascular reaction by diabetes mellitus was revealed. Expedience for the clinical practice the complex functional-pharmacologic test was demonstrated. Key words: central hemodinamics, cardiohemodinamics, diabetes mellitus, arterial hypertension, functional tests, capoten, adverzutene.

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