A?eioea?eianueeee aea?aeaaiee aa?a?iee oiiaa?neoao

*i?iicoa Ieeiea Iao?iae/

OAeE 619: 617. 57/. 58]: 636. 2. 053.

Ci?ie a?ee?a ? a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa
ne?iaaooe? e?ia? i?e anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi?
ooaeiae (ee?i?ei-aenia?eiaioaeuei? aeine?aeaeaiiy)

16.00.05 – aaoa?eia?ia o??o?a?y

Aaoi?aoa?ao

aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa aaoa?eia?ieo iaoe

Aiea Oea?eaa — 1999

Aeena?oaoei?th ? ?oeiien.

?iaioa aeeiiaia a Aieioea?eianueeiio aea?aeaaiiio aa?a?iiio
oiiaa?neoao?

Iaoeiaee ea?iaiee aeieoi? aaoa?eia?ieo iaoe,i?ioani?

Icaeainueeee Aioaeie Eineiiae/,
Iieoaanueeee

aea?aeaaiee
nieuenueeiainiiaea?nueeee iinoeooo,

caaiaeoaa/ eaoaae?e oi?o?ai? oa
aeooa?noaa

Ioioeieii iiiiaioe:

aeieoi? aaoa?eia?ieo iaoe, i?ioani? eaoaae?e o??o?a??
Iaoe?iiaeueiiai aa?a?iiai oi?aa?neoaooAi?enaae/ Aieiaeeie? Ai?eniae/

eaiaeeaeao aiieiai/ieo iaoe, aeioeaio TH?/aiei Eaii?ae ?aaiiae/,

Oa?e?anueeee ciiaaoa?eia?iee ?inoeooo, caaiaeoaa/ eaoaae?e oi?o?ai?

I?iaiaeia onoaiiaa

Ai?iiacueeee aea?aeaaiee aa?a?iee oi?aa?neoao, i. Ai?iiaae, ?inienueea
Oaaea?aoe?y

Caoeno aeena?oaoei? aiaeaoaeaoueny «__23_.09. 1999 ?. i __14 aiaeeii ia
caniaeaiii niaoeiaeiciaaii? a/aii? ?aaee Ae 27.821.02 i?e
Aieioea?eianueeiio aea?aeaaiiio aa?a?iiio oiiaa?neoaoi ca aae?anith:
256400, Ee?anueea iaeanoue, i. Aiea Oea?eaa, aoe. Noaaeuainueea,
126; iaa/aeueiee ei?ion 5, aoae. 1

C aeena?oaoei?th iiaeia iciaeiieoenue o aiaeiioaoei Aieioea?eianueeiai
aea?aeaaiiai aa?a?iiai oiiaa?neoaoo: i. Aiea Oea?eaa, Niai?ia ieiua,
8/1.

Aaoi?aoa?ao ?icineaiee «__21___»___08____1999 ?ieo.

A/aiee nae?aoa? niaoeiaeiciaaii? a/aii?

?aaee, eaiaeeaeao aaoa?eia?ieo iaoe
I.I.Noaaeiee

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Cia/iiai iioe?aiiy na?aae iiaie?a’y aaeeei? ?iaaoi?
ooaeiae iaaoee a?o?eoe ?ioaeoe?eiiai oa ia?ioaeoe?eiiai iioiaeaeaiiy.
A.N. Naiaiia (1985) iia?aeiiey?, ui, caeaaeii a?ae oiia oo?eiaiiy,
caoai?thaai?noue ia a?o?eo na?aae ei??a oa iieiaeiyeo ia a?aeaiae?ae?
iiaea noaiiaeoe 6–11,2%. Ca aeaieie A.A. Ai?enaae/a (1989), o ca’yceo c
ae??th eiiieaeno ao?ieia?/ieo oaeoi??a a?o?eoe iiaeooue cono??/aoeny o
3–7% iiaie?a’y oaa?ei. I?e ianoaaeaii? aeayeeo ainiiaea?noa Ee?anueei?
iaeano? N.A. ?oaeaiei ? A.E. ?caeainueeee (1997) aeyaeyee 2,9–3,6%
oaa?ei, oai?eo ia a?o?eo. I?e aeaiiio caoai?thaaii? ao?aoe iiei/ii?
i?iaeoeoeaiino? iiaeooue neeaaeaoe 30–45%, ciaioaiiy na?aaeiueiaeiaiaiai
i?e?inoo iane o?ea – 6–9% (A?aothoa ?.N., Ai?enaae/ A.A., 1988).

Caaaeath/e ia iioe?aiiy oai?ia noaeia?a na?aae iiaie?a’y aaeeei?
?iaaoi? ooaeiae, ?nio? iio?aaa a ii?aoethaaii? iiaeo, a?eueo aoaeoeaieo
iaoiae?a oa cania?a e?eoaaiiy oe??? iaoieia??. Oea, o naith /a?ao,
iio?aao? a?eueo aeeaieiai aea/aiiy iaoai?ci?a ?icaeoeo oa ia?aa?ao
aeaiiai caoai?thaaiiy o oaa?ei.

Ieoaiith iaoiaaiaco a?o?eo?a o oaa?ei i?enay/aii aaaaoi iaoeiaeo
i?aoeue. I?ioyaii o?eaaeiai /ano aeine?aeieeaie aea/a?oueny ?ieue
i?aeaeuaiiai aioo??oiueinoaeiaiaiai oeneo oa ?ioa?ioeaioe?? noaeiaa a
?icaeoeo a?o?eo?a, ci?ie a?eeiaiai neeaaeo a neiia?aeuei?e ??aeei?,
i?iieeiino? eai?ey?ii-oeaieiiiai aa?’??o neiia?aeueii? iaieiiee, aieea
nainea?e?caoe?? ia ?icaeoie oa ia?aa?a a?o?eo?a o ae/e?a, noai
i?ioaie?oe/ii? oa o?a?eiie?oe/ii? nenoai neiia?aeueii? ??aeeie i?e
aeaiiio caoai?thaaii? (Iiaaaeaiei E.A., 1948; Ai?enia I.N., 1972;
Iaoaaaa A.A., 1978; Naiaiia A.N., 1985; ?oaeaiei N.A., ?caeainueeee
A.E., 1997).

I?ioa, i?e aea/aii? anaioe/ieo a?o?eo?a iica oaaaith ia?aaoaaei cia/aiiy
a?ee?a aino?i? oace, n?aeiaeo eeneio, ae?eii?ioa?ae?a, ye? aeeiiothoue a
i?aai?ci? ooieoe?th ianiaoeeo?/iiai caoenoo, a ?o eiioeaio?aoe?y ?
ianiaoeeo?/iei iieacieeii ?aaeoeaiino? i?aai?cio (Ao?aiia I.I., 1982;
Noaeieueieeia A.A., 1985). Caeeoathoueny iac’yniaaieie i?iaeaie
ii?ooaiiy iai?io ae?eicai?iiae?eai?a, ??aaiue yeeo a?aeia?aaea?
iayai?noue aeano?oeoeaieo i?ioean?a o oeaieiao (Iaaa?ia E.A., Oeoi?aiei
I.E., 1979).

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa
aeeiioaaeany ca?aeii c eaoaae?aeueiith oaiaoeeith iaoeiai-aeine?aeii?
?iaioe.

Iaoa ?iaioe. Iaoith aeine?aeaeaiiy aoei aea/aiiy ci?i ai?noo a?ee?a ?
a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia?
i?e anaioe/ieo a?o?eoao ? ii?aoethaaiiy ia oe?e iniia? iaoiaaiaoe/ii
iaa?oioiaaieo iaoiae?a ?o e?eoaaiiy.

Aeey aeinyaiaiiy iaoe iaiao?aeii aoei ae??oeoe ianooii? caaaeaiiy:

– aea/eoe ai?no caaaeueiiai a?eea ? eiai neeaae, cie?aia ??aaiue a?ee?a
aino?i? oace, o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? iieiaeiyeo
aaeeei? ?iaaoi? ooaeiae a ii?i? ? a aeeiai?oe? anaioe/ieo a?o?eo?a;

– aea/eoe ai?no n?aeiaeo eeneio, ae?eii?ioa?ae?a, ae?eicai?iiae?eai?a o
neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? iieiaeiyeo aaeeei? ?iaaoi?
ooaeiae a ii?i? ? a aeeiai?oe? anaioe/ieo a?o?eo?a;

– ii?aoethaaoe oa i?iaanoe ee?i?/io ioe?ieo ? iaoiaaiaoe/ia
iaa?oiooaaiiy aeayeeo iaoiae?a e?eoaaiiy i?e anaioe/ieo a?o?eoao o
iieiaeiyeo aaeeei? ?iaaoi? ooaeiae.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a.

1. Aia?oa aea/aii ??aaiue a?ee?a aino?i? oace, n?aeiaeo eeneio,
ae?eii?ioa?ae?a oa ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei? oaeyo o
ii?i?.

2. Aia?oa aea/aii aeeiai?eo a?ee?a aino?i? oace, n?aeiaeo eeneio,
ae?ei-i?ioa?ae?a oa ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei? i?e
anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae.

3. Aia?oa aea/aii aoaeoeai?noue ? iaoeiai iaa?oioiaaii iaoiaaiaoe/iee
iaoiae e?eoaaiiy i?e anaioe/ieo a?o?eoao o oaeyo oeyoii
aioo??oiueinoaeiaiai? ?i’?eoe?? iie?a?i?ei??ie?aeiio (ooo/iiai cai?iieea
neiia?aeueii? ??aeeie) c a?ae?iei?oeciiii oa e?aeiea?iii.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a iieyaa? o oiio, ui aaoi?ii
?ice?eo? iia? iaoai?cie iaoiaaiaco anaioe/ieo a?o?eo?a o iieiaeiyeo
aaeeei? ?iaaoi? ooaeiae, ii?aoeueiaaiee aoaeoeaiee iaoiae ?o e?eoaaiiy
oeyoii aioo??oiueinoaeiaiai? ?i’?eoe?? iie?a?i?ei??ie?aeiio c
a?ae?iei?oeciiii oa e?aeiea?iii.

Iaea?aeai? ?acoeueoaoe aeei?enoiaothoueny i?e /eoaii? eaeoe?e oa
i?iaaaeaii? eaai?aoi?ii-i?aeoe/ieo caiyoue c o??o?a?? ia oaeoeueoaoao
aaoa?eia?ii? iaaeeoeeie A?eioea?e?anueeiai AeAO, IAO, Iieoaanueeiai
aea?aeaaiiai n?euenueeiainiiaea?nueeiai ?inoeoooo, a ?inoeooo?
i?neyaeeieiiiiai iaa/aiiy ENAI i?e AAeAO, i?e e?eoaaii? oaa?ei o
o??o?a?/i?e ee?i?oe? oi?aa?neoaoo oa o ainiiaea?noaao Ee?anueei?
iaeano?.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii naiino?eii aeeiiaii aanue ianya
aenia?eiaioaeueieo aeine?aeaeaiue, c?iaeaii aiae?c oa ocaaaeueiaiiy
iaea?aeaieo ?acoeueoao?a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe ?iaioe aeiiia?aeaeenue
ia ui??/ieo iaoeiai-i?aeoe/ieo eiioa?aioe?yo
i?ioani?nueei-aeeeaaeaoeueeiai neeaaeo A?eioea?e?anueeiai AeAO, ??-e
I?aeia?iaei?e iaoeiai-i?aeoe/i?e eiioa?aioe?? c i?iaeai ia?ioaeoe?eii?
iaoieia?? oaa?ei (i. A?ea Oea?eaa, 45 /a?aiy 1998 ?.), ia can?aeaii?
iaoeiai-oaoi?/iiai oiaa?enoaa ?i. ?.?. Ia/ieeiaa A?eioea?e?anueeiai
AeAO.

Ioae?eaoe??. ?acoeueoaoe aenia?eiaioaeueieo aeine?aeaeaiue iioae?eiaai?
o 5 noaooyo, ui aeeoee o «A?nieeo A?eioea?e?anueeiai aea?aeaaiiai
aa?a?iiai oi?aa?neoaoo».

No?oeoo?a oa ianya aeena?oaoe??. ?iaioa aeeeaaeaia ia 164 noi??ieao
iaoeiiieniiai oaenoo, ?ethno?iaaia 9 ?enoieaie, 18 oaaeeoeyie ? aeeth/a?
anooi, iaeyae e?oa?aoo?e, aeani? aeine?aeaeaiiy oa ?o iaaiai?aiiy,
aeniiaee oa i?iiiceoe?? ae?iaieoeoao, nienie aeei?enoaieo e?oa?aoo?ieo
aeaea?ae c 317 , o oiio /ene? 54 ?iicaiieo.

AEA?? IAI?ssI?A AeINE?AeAEAIIss, IAOA??AE OA IAOIAeE AEEIIAIIss ?IAIOE

Aeine?aeaeaiiy aeeiioaaeenue i?ioyaii 1996–1999 ??. o ENI ?i. Aaooo?ia
oa «Iaye» Ee?anueei? iaeano?, a iaa/aeueii-aeine?aeiiio ainiiaea?noa? oa
a oiiaao ee?i?ee eaoaae?e o??o?a?? A?eioea?e?anueeiai AeAO. Ca oeae
ia??iae aoei i?aeaeaii ee?i?/iiio ianoaaeaiith 1432 aieiae aaeeei?
?iaaoi? ooaeiae ??cieo a?eiaeo a?oi, c yeeo aoei aeyaeaii 246 oaa?ei
(17,18%) c o??o?a?/ieie caoai?thaaiiyie e?ioe?aie. Na?aae ieo ia a?o?eo
oai??ei 49 aie?a (19,92%). Ia?aaaaeii a?aaeaany oa?caeueiee noaeia,
caiaeueiee i?ioean oa?aeoa?ecoaaany anaioe/iei ia?aa?aii.

Ine?eueee niiioaii? a?o?eoe aeieeaee ia iaeii/anii ? ae?aaiinooaaeenue
ia ??cieo noaae?yo caoai?thaaiiy, ui ia aeaaaei iiaeeeaino? aea/aoe
ci?ie o neeaae? neiia?aeueii? ??aeeie a aeeiai?oe? caiaeueiiai i?ioeano,
iaoa??aeii aeey aeeiiaiiy aeena?oaoe?eii? ?iaioe aoee ae/ee /i?ii-?yai?
ii?iaee 4–6-i?ny/iiai a?eo c aenia?eiaioaeueii aeeeeeaieie ca
iaoiaeeeith A.N. Naiaiiaa (1979) anaioe/ieie a?o?eoaie.

A?aeiia?aeii aei iinoaaeaieo caaaeaiue aoei i?iaaaeaii o?e na???
aeine?ae?a c aea/aiiy a?eeiaiai neeaaeo, ai?noo n?aeiaeo eeneio,
ae?eii?ioa?ae?a, ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei? oa
ne?iaaooe? e?ia? iieiaeiyeo aaeeei? ?iaaoi? ooaeiae a ii?i?, i?e
anaioe/ieo a?o?eoao oa i?e aeayeeo iaoiaeao ?o e?eoaaiiy.

O ia?o?e na??? aeine?ae?a (16 aie?a) aea/aee iacaai? iieacieee o
neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? ee?i?/ii caei?iaiai iieiaeiyeo
aaeeei? ?iaaoi? ooaeiae, ye? a iiaeaeueoiio aaaaeaee ca ii?io.
Neiia?aeueio ??aeeio io?eioaaee oeyoii ioieoe?? oa?caeueiiai noaeiaa
/a?ac ia?aaeiueiciai?oi?e /e ia?aaeiueiaioo??oi?e aeai?ioe.

O ae?oa?e na??? aeine?ae?a (16 aie?a) aea/aee ci?ie a?eeiaiai neeaaeo,
ai?noo n?aeiaeo eeneio, ae?eii?ioa?ae?a, ae?eicai?iiae?eai?a o
neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? iieiaeiyeo aaeeei? ?iaaoi?
ooaeiae a aeeiai?oe? aenia?eiaioaeueii aeeeeeaiiai anaioe/iiai a?o?eoo
oa?caeueiiai noaeiaa.

Aenia?eiaioaeuei? a?o?eoe aeeeeeaee ia oii? nainea?e?caoe??. Aeey
oeueiai oaa?eiai i?aeoe??ii aaiaeeee na?aeo ne?iaaoeo e?ia? eiiy ii 15
ie o?e/?, c ?ioa?aaeii o 2 aeiae. Ia 21-e aeaiue a?ae inoaiiuei?
nainea?e?coth/i? ?i’?eoe?? i?ney nii?iaeiyth/i? ioieoe?? oa?caeueiiai
noaeiaa a eiai ii?iaeieio aaiaeeee 10 ie 20%-iiai ?ic/eio iao??th
oei?eaeo oa 0,3 ie oa?iaioeiiai? ie??. O aeeiai?oe? caoai?thaaiiy
i?iaiaeeee caaaeueia aeine?aeaeaiiy oaa?ei oa ianoaaeaiiy o?aaeaiiai
noaeiaa, i?e yeiio caa?oaee oaaao ia iciaee i?noeaai? caiaeueii?
?aaeoe??: oaiia?aoo?o, a?eue, eiinenoaioe?th ia?aa?oeeoey?ieo oeaiei oa
aeai?io?a noaeiaa, i?aaiieaioe/i? iieacieee neiia?aeueii? ??aeeie. Ia
3-th, 7-o ? 11-o aeiao caoai?thaaiiy i?iaiaeeee aeine?aeaeaiiy
ii?oieia?/iiai neeaaeo e?ia?, a?eeiaiai neeaaeo, ai?noo n?aeiaeo eeneio,
ae?eii?ioa?ae?a ? ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei? o?aaeaiiai
noaeiaa oa ne?iaaooe? e?ia? oaa?ei.

O o?ao?e na??? aeine?ae?a ii?aoeueiaaii oa i?iaaaeaii ee?i?/io ioe?ieo
? iaoiaaiaoe/ia iaa?oiooaaiiy iaoiaeo e?eoaaiiy i?e anaioe/ieo a?o?eoao
o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae. O ca’yceo c oeei aoei noi?iiaaii
aeine?aeio (10 aie.) oa eiio?ieueio (11 aie.) a?oie ae/e?a c
aenia?eiaioaeueieie anaioe/ieie a?o?eoaie oa?caeueiiai noaeiaa,
e?eoaaiiy yeeo i?iaiaeeee ia 3-th aeiao caoai?thaaiiy. Oaa?eiai
aeine?aeii? a?oie i?ney nii?iaeiyth/i? ioieoe?? ii?iaeieie noaeiaa
aioo??oiueinoaeiaiai iaeii?aciai ?i’?eooaaee 10–15 ie 15%-iiai ?ic/eio
iie?a?i?ei??ie?aeiio c aeiaeaaaiiyi 2 ie (50 ia) noniaic??
a?ae?iei?oeciio aoeaoaoo, 1 ie 10%-iiai ?ic/eio e?aeiea?io
a?ae?ioei?eaeo oa 1 ie 4%-iiai ?ic/eio aaioai?oeeio noeueoaoo. O
eiio?ieuei?e a?oi? e?eoaaiiy i?iaiaeeee caaaeueiii?eeiyoei iaoiaeii:
aioo??oiueinoaeiaiai ?i’?eooaaee 5–6 ie (125–150 ia) noniaic??
a?ae?iei?oeciio aoeaoaoo oa 10 ie 0,5%-iiai ?ic/eio iiaiea?io c
aeiaeaaaiiyi 1 ie 4%-iiai ?ic/eio aaioai?oeeio noeueoaoo. I?e
iaiao?aeiino? aeayeei oaa?eiai ?i’?eoe?th iiaoi?thaaee ia 5-o aeiao
e?eoaaiiy.

O i?ioean? e?eoaaiiy i?iaiaeeee caaaeueia aeine?aeaeaiiy oaa?ei iaio
a?oi, ianoaaeaiiy o?aaeaiiai noaeiaa, a ia 5-o oa 9-o aeiao e?eoaaiiy
aeine?aeaeoaaee ii?oieia?/iee neeaae e?ia?, ai?no a?ee?a, n?aeiaeo
eeneio, ae?eii?ioa?ae?a, ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei?
o?aaeaiiai noaeiaa oa ne?iaaooe? e?ia?.

Aaiaoieia?/i? aeine?aeaeaiiy (e?euee?noue a?eo?ioeeo?a, eaeeioeeo?a,
??aaiue aaiiaeia?io oa eaeeia?aio) i?iaiaeeee caaaeueiii?eeiyoeie
iaoiaeaie.

O neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? aecia/aee ai?no caaaeueiiai
a?eea (oi?o?eiaaiei iaoiaeii ca a?o?aoiaith ?aaeoe??th), a?eeiaee neeaae
(oeyoii ciiaeueiiai aeaeo?ioi?aco aeine?aeiiai iaoa??aeo a
iie?ae?eeai?aeiiio aae? c ianooiiei oa?aoaaiiyi 0,25%-iei ?ic/eiii
Eoiann? a?eeueyioiaiai aeaeeoiiai R-250 oa aeaineoiiao???th ia
aiae?caoi?? oi?aa?ai AO-1 ca B.G.Davis, 1964), ai?no n?aeiaeo eeneio
(oioiaeaeo?ieiei?eiao?e/iei iaoiaeii ca F.Hess, 1957), ??aaiue
ae?eii?ioa?ae?a oa ae?eicai?iiae?eai?a (o?aeoe?eiei iaoiaeii ca
E.A.Iaaa?iaui oa I.E.Oeoi?aiei, 1979).

Io?eiaiee oeeo?iaee iaoa??ae ia?iaeaiee noaoenoe/ii ia i?ia?aiiaaiiio
i?e?ieaeueeoeyoi?? «SHARP» EL-506 P c aecia/aiiyi na?aaeiuei?
a?eoiaoe/ii? (M), noaoenoe/ii? iiieeee na?aaeiuei? a?eoiaoe/ii? (m).
A??ia?aei?noue ??cieoe? (p) i?ae na?aaei?ie a?eoiaoe/ieie aeaio
aa??aoe?eieo ?yae?a aecia/aee ca e?eoa???i aeinoia??iino? (t) ?
oaaeeoeyie Nouethaeaioa. ??cieoeth i?ae aeaiia aaee/eiaie aaaaeaee
a??ia?aeiith i?e ??ai?e iiaeeeaino? p<0,05; 0,01; 0,001. ?ACOEUeOAOE AeINE?AeAEAIUe OA ?O AIAE?C Ee?i?ei-aaiaoieia?/i? ci?ie i?e aenia?eiaioaeueieo anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae C aeieeiaiiyi aenia?eiaioaeueieo anaioe/ieo a?o?eo?a iaea?eueoi? ?ioaineaiino? caiaeueia ?aaeoe?y iaaoaaea ia 3-th aeiao caoai?thaaiiy. Oai?? oaa?eie caeaa?eueoiai ia?aaoaaee o eaaea/iio iieiaeaii?. I?aeaeuoaaeanue oaiia?aoo?a o?ea (39,6–40,00N), /anoioa ioeueno (100–110 iiooiao?a ca oa) oa aeeoaiiy (26–32 aeeoaeueieo ?oo?a ca oa). I?ae /an ?ooo niinoa??aaee eoeueaaa?noue ii??ii? e?ioe?aee aenieiai nooiaiy, o niiei? oai?a e?ioe?aea aoea o iai?ac?aiooiio a oa?caeueiiio noaeia? iieiaeaii? ? oi?eaeanue i?aeeiae eeoa ca/aiii. Ianeai? ?ooe o noaeia? aeeeeeaee neeueiee a?eue. I?noeaai aeyaeyee ca?eueoaiiy ia’?io o?aaeaiiai noaeiaa (aeiaaeeia iaoaaoo neeaaeaea 37,0–39,5 ni i?ioe 29,0–30,0– o caei?iaeo oaa?ei), ia/?oe?noue eiai eiioo??a oa ?iceeoa, aa?y/a ia aeioee ? neeueii aieth/a i?eiooaiiy oeaiei. Aeai?ioe noaeiaa aoee a?ae/ooii aeiiaiai? ? oeoeooth/?, i?e ?o ioieoe?? aeae?eyeanue cia/ia e?euee?noue ??aeei? iai?ici?i? neiia?? a?ae nieii’yii-aeiaoiai aei oaiii-aeiaoiai eieuei?o c ieano?aoeyie o?a?eio. O oeae /an o e?ia? aeyaeyee ciaioaiiy e?eueeino? a?eo?ioeeo?a (a 1,4 ?ace; ?0,001), ??aiy aaiiaeia?io (a 1,3 ?ace; ?0,01) oa ca?eueoaiiy ai?noo eaeeioeeo?a (a 1,3 ?ace; ?0,01). O eaeeia?ai? a?aeaoaaeinue ca?eueoaiiy e?ioioeeo?a (a 1,2 ?ace; ?0,001), iiiioeeo?a (o 2,3 ?ace; ?0,001), aiceiio?e?a (a 1,7 ?ace; ?0,01), iaee/eiyaea?ieo (a 1,8 ?ace; ?0,001) oa thieo (?0,001) iaeo?io?e?a i?e ciaioaii? naaiaioiyaea?ieo ?o oi?i (o 2,1 ?ace; ?0,001). ?c 7-? aeiae caoai?thaaiiy a?aeaoaaeinue aeayea iie?auaiiy caaaeueiiai noaio oaa?ei oa ?o ?ooiai? aeoeaiino?. Caaaeueia oaiia?aoo?a o?ea, /anoioa ioeueno oa aeeoaiiy eieeaaeenue o o?c?ieia?/ieo iaaeao. A?aeaoaaeinue aeayea cieaeaiiy aeoeaiino? caiaeueii? ?aaeoe??. I?e ioieoe?? noaeia?a aeyaeyee cieaeaiiy a’yceino? neiia?aeueii? ??aeeie, a a aeayeeo oaa?ei – ciaioaiiy ?? e?eueeino?. Ia 11-o aeiao caoai?thaaiiy o a?eueoino? oaa?ei (69%) i?ae /an ?ooo niinoa??aaee eoeueaaa?noue iecueeiai nooiaiy oa /anoeiaa iie?aiiy oai?ith e?ioe?aeith o niiei?. I?noeaai aeyaeyee ciaioaiiy ia’?io o?aaeaiiai noaeiaa (aei 33,5–34,5 ni) oa iaiaaeaia, u?eueia, aieth/a, iaaa?y/a i?eiooaiiy oeaiei o eiai ae?eyioe?. I?ioa, o /anoeie oaa?ei (31%) a?aei?/aee eoeueaaa?noue na?aaeiueiai nooiaiy oa aeia?a ae?aaeai? iciaee i?noeaai? caiaeueii? ?aaeoe??. O aaaaoueio oaa?ei niinoa??aaee ciaioaiiy e?eueeino? neiia?aeueii? ??aeeie ia oii? cieaeaii? ?? a’yceino?. O oeae /an o oai?eo oaa?ei, ii??aiyii c? caei?iaeie, aoa ieae/ee ??aaiue aaiiaeia?io (a 1,2 ?ace; ?0,05), a?eo?ioeeo?a (a 1,3 ?ace; ?0,05) oa eaeeioeeo?a (a 1,2 ?ace; ?0,05). Iieacieee eaeeia?aie iaee oaiaeaioe?th aei ii?iae?caoe??, i?ioa ?noioii ieae/ei aoa ??aaiue naaiaioiyaea?ieo iaeo?io?e?a (?0,001). O iiaeaeueoiio (20–35-a aeiaa caoai?thaaiiy) a a?eueoino? oaa?ei (81%) aoea a?aenooiy eoeueaaa?noue i?ae /an ?ooo, aiie iiai?noth iie?aeeny o?aaeaiith e?ioe?aeith o niiei?, iciaee i?noeaai? caiaeueii? ?aaeoe?? a ae?eyioe? noaeiaa ia niinoa??aaeenue. I?ioa, o /anoeie oaa?ei (19%) iaa?oue ia 45-o aeiao a?ae ii/aoeo caoai?thaaiiy aeyaeyee eoeueaaa?noue iecueeiai nooiaiy i?ae /an ?ooo, ca?eueoaiiy ia’?io o?aaeaiiai noaeiaa oa iaiaaeaia, ou?eueiaia, ia aieth/a ? ia aa?y/a i?eiooaiiy eiai oeaiei, ui na?ae/eoue i?i ?icaeoie o?ii?/iiai o?a?iceoo. Oaeei /eiii, aenia?eiaioaeuei? anaioe/i? a?o?eoe oa?aeoa?ecothoueny a?ia?a?a?/iei oeiii caiaeaiiy ? o?eaaeei eiai ia?aa?aii i?e iayaiino? ?iceeoiai, aa?y/iai ? aieth/iai i?eiooaiiy oeaiei o ae?eyioe? noaeiaa, na?icii-o?a?eiiciiai aeiioo a eiai ii?iaeieio, ?noioiei iia??oaiiyi caaaeueiiai noaio oaa?ei, i?eai?/aiiyi a?eo?iiiaco. C iiaeaeueoei ia?aa?aii caoai?thaaiiy iiaeeea? ye ee?i?/ia naiiaeaeoaeaiiy oaa?ei, oae ? oneeaaeiaiiy (o?ii?/iee o?a?iceo o?aaeaiiai noaeiaa). Ci?ie ai?noo caaaeueiiai a?eea ? eiai o?aeoe?e o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? i?e aenia?eiaioaeueieo anaioe/ieo a?o?eoao Neiia?aeueia ??aeeia ee?i?/ii caei?iaiai iieiaeiyeo aaeeei? ?iaaoi? ooaeiae i?noeoue o 5,8 ?ac?a iaioa caaaeueiiai a?eea, i?ae ne?iaaoea e?ia? (?0,001). Neeaae a?eea neiia?aeueii? ??aeeie oa ne?iaaoee e?ia? iiae?ai? a ye?niiio, aea a?ae??ciythoueny o e?euee?niiio a?aeiioaii? ? aeeth/athoue ianooii? o?aeoe?? (%): i?aaeueaoi?ie (2,860,26 o neiia?? oa 1,880,14 o ne?iaaooe?), aeueaoi?ie (a?aeiia?aeii 40,211,61 oa 29,680,85), -aeiaoe?ie (15,580,50 oa 13,340,40), oea?oeiieaci?i (3,700,27 oa 2,890,15), o?ainoa?eie (6,220,22 oa 6,900,21), aaioiaeia?ie (7,000,20 oa 6,090,20), Ig G (15,270,59 oa 27,550,50), A (5,220,27 oa 7,590,49), a?eee S-o?aeoe?? (3,940,26 oa 4,080,14). ?c ?icaeoeii aenia?eiaioaeueiiai anaioe/iiai a?o?eoo (3-y aeiaa caoai?thaaiiy) a?aeaoaaeinue ca?eueoaiiy eiioeaio?aoe?? caaaeueiiai a?eea o ne?iaaooe? e?ia? (a 1,1 ?ace; ?0,001) ?, iniaeeai, a neiia?aeuei?e ??aeei? (o 4,9 ?ace; ?0,001). O iiaeaeueoiio (7-a ? 11-a aeiaa caoai?thaaiiy) eiai ??aaiue o ne?iaaooe? e?ia? cieaeoaaany aei ii?ie (?0,05), a o neiia?aeuei?e ??aeei? ?noioii a?ae??ciyany a?ae ai?noo o caei?iaeo oaa?ei (?0,001) ? aoa o 5,4 ?ac?a aeuei ia 7-o aeiao caoai?thaaiiy oa o 4,5 ?ac?a – ia 11-o. Ia 3-th aeiao caoai?thaaiiy o neiia?aeuei?e ??aeei? i?aeaeueany a 1,8 ?ace ??aaiue Ig G (aei 27,000,60%; ?0,001), a 1,6 ?ace – Ig A (aei 8,540,32%; ?0,001), a 1,2 ?ace – aaioiaeia?i?a (aei 8,480,20%; ?0,001), o?ainoa?ei?a (aei 7,740,17%; ?0,001), a 1,7 ?ace – oea?oeiieaci?io (aei 6,200,16%; ?0,001) oa ciaioeany a 1,9 ?ace ai?no aeueaoi?i?a (aei 21,110,81%; ?0,001), a 1,1 ?ace– -aeiaoe?i?a (aei 13,730,40%; ?0,001). O ne?iaaooe? e?ia? a oeae ia??iae ciaioeany ai?no Ig G (aei 24,550,29%; ?0,001), i?aeaeueany ??aaiue aaioiaeia?i?a (aei 7,550,13%; ?0,001), o?ainoa?ei?a (aei 8,450,17%; ?0,001), oea?oeiieaci?io (aei 4,770,22%; ?0,001), a??ia?aeieo ci?i ?ioeo o?aeoe?e ia aeyaeaii (?0,05). Ia 7-o aeiao caoai?thaaiiy, ii??aiyii c iiia?aaei?i aeine?aeaeaiiyi, o neiia?aeuei?e ??aeei? i?aeaeueany ??aaiue i?aaeueaoi?i?a (a 1,6 ?ace; ?0,001), Ig G (ia 3,2%; ?0,01), A (ia 1,78%; ?0,001), a?ee?a S-o?aeoe?? (a 1,7 ?ace; ?0,001), cieceany ai?no aeueaoi?i?a (a 1,3 ?ace; ?0,01), -aeiaoe?i?a (ia 1,63%; ?0,01) oa a?ee?a aino?i? oace – oea?oeiieaci?io (a 1,4 ?ace; ?0,001), o?ainoa?ei?a (ia 0,84%; ?0,05), aaioiaeia?i?a (ia 0,82%; ?0,01). O ne?iaaooe? e?ia?, a?aeiia?aeii, i?aeaeueany ai?no Ig G (ia 2,44%; ?0,05) ? ciaioeany oea?oeiieaci?io (o 2,1 ?ace; ?0,001). Oaaeeoey 1 Ai?no caaaeueiiai a?eea o ne?iaaooe? e?ia? oa neiia?aeuei?e ??aeei? a aeeiai?oe? anaioe/iiai a?o?eoo, a/e ??aeeie Caei?ia? Aeiaa caoai?thaaiiyo?aai?cioOaa?eie3-y7-a11-aNe?iaaoea e?ia?66,02 1,5073,13 0,5664,68 2,19*68,30 1,80*Neiia?aeueia ??aeeia11,45 0,6755,47 1,2361,95 4,5951,82 7,88I?ei?oea. * ?0,05, ii??aiyii c ee?i?/ii caei?iaeie oaa?eiaie. Ci?ie ?aooe iieaciee?a a??ia?aei?. O iiaeaeueoiio (ia 11-o aeiao caoai?thaaiiy) o neiia?aeuei?e ??aeei? aoa iaioee ai?no aeueaoi?i?a (o 2,3 ?ace; ?0,001), -aeiaoe?i?a (a 1,3 ?ace; ?0,01), i?aeaeuaiee ??aaiue i?aaeueaoi?i?a (a 1,8 ?ace; ?0,01), oea?oeiieaci?io (a 1,8 ?ace; ?0,001), Ig G (a 1,8 ?ace; ?0,001), A (o 2 ?ace; ?0,001), a?ee?a S-o?aeoe??? (a 1,7 ?ace; ?0,01), ii??aiyii c? caei?iaeie oaa?eiaie. O ne?iaaooe? e?ia?, a?aeiia?aeii, aoa ieae/ee ??aaiue i?aaeueaoi?i?a (a 1,5 ?ace; ?0,01), -aeiaoe?i?a (ia 0,99%; ?0,05), i?aeaeuaiee ai?no o?ainoa?ei?a (ia 0,68%; ?0,05), Ig G (ia 1,71 %; ?0,05). Uiaei ?ioeo o?aeoe?e a??ia?aeieo ci?i ia aoei aeyaeaii (?>0,05).

O a?aeaeaeaiee a?ae ii/aoeo caoai?thaaiiy oa?i?i (45-a aeiaa) ai?no
caaaeueiiai a?eea o neiia?aeuei?e ??aeei? ia iiaa?oaany aei ii?ie o
aeaeoaeaeeo ia oeae /an oaa?ei (18,672,50 a/e; ?0,01) ?, iniaeeai,
oai?eo ia o?ii?/iee o?a?iceo (31,032,60 a/e; ?0,001). Caeeoaeanue
?noioiith ??cieoey o?aeoe?eiiai neeaaeo a?eea neiia?aeueii? ??aeeie i?ae
caei?iaeie oaa?eiaie, oeie, ui aeaeoaeaee oa oai?eie ia o?ii?/iee
o?a?iceo: aoa cieaeaiee ??aaiue aeueaoi?i?a (o 2,9 ?ace o oai?eo oa o 2
?ace o aeaeoaeaeeo; ?0,001), i?aeaeuaiee ai?no -aeiaoe?i?a (a?aeiia?aeii
a 1,4 oa 1,3 ?ace; ?0,001), Ig G (a 1,6 oa 1,3 ?ace; ?0,001), A (a 1,8
?ace; ?0,001 oa a 1,5 ?ace; ?0,01), a?ee?a S-o?aeoe?? (a 1,8 oa 1,5
?ace; ?0,001). O oaa?ei, ui aeaeoaeaee, aoa i?aeaeuaiee a 1,3 ai?no
aaioiaeia?io (?0,01), a 1,3 ?ace – i?aaeueaoi?i?a (?0,05), a 1,5 ?ace –
o?ainoa?ei?a (?0,05), o oai?eo ia o?ii?/iee o?a?iceo – a 1,6 ?ace
oea?oeiieaci?io (?0,001) oa a 1,2 ?ace – aaioiaeia?i?a (?0,001).

Oaeei /eiii, c ?icaeoeii aenia?eiaioaeueiiai anaioe/iiai a?o?eoo, o
ca’yceo c ?noioiei ca?eueoaiiyi i?iieeiino? neiia?aeueii? iaieiiee, o
neiia?aeuei?e ??aeei? i?aeaeuo?oueny ai?no aenieiiieaeoey?ieo a?ee?a i?e
iaaeinoaoiueiio ca?eueoaii? ?? ?ia?a?oi?iiai iioaioe?aeo. Ai?no a?ee?a
aino?i? oace ye oaeoi??a ianiaoeeo?/iiai caoenoo i?aai?cio
i?aeaeuo?oueny ia ii/aoeo caoai?thaaiiy, aea cieaeo?oueny c iiaeaeueoei
eiai ia?aa?aii. Aeaeoaeaiiy oaa?ei a?aeaoaa?oueny ia oii? i?aeaeuaiiy
ai?noo a?ee?a aino?i? oace oa ?ia?a?oi?iiai iioaioe?aeo neiia?aeueii?
??aeeie.

Ci?ie ai?noo a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa
ne?iaaooe? e?ia? i?e aenia?eiaioaeueieo anaioe/ieo a?o?eoao

Neiia?aeueia ??aeeia ee?i?/ii caei?iaeo oaa?ei, ii??aiyii ?c ne?iaaoeith
e?ia?, i?noeoue o 25,6 ?ac?a iaioa n?aeiaeo eeneio (?0,001), o 3,2 ?ace
– ae?eii?ioa?ae?a (?0,001), o 13,6 ?ac?a – ae?eicai?iiae?eai?a
(?0,001).

C ?icaeoeii aenia?eiaioaeueiiai anaioe/iiai a?o?eoo (3-y aeiaa
caoai?thaaiiy) o neiia?aeuei?e ??aeei? ?noioii i?aeaeuoaaany ??aaiue
n?aeiaeo eeneio (o 25,5 ?ace; ?0,001), ae?eii?ioa?ae?a (o 4,6 ?ace;
?0,001) oa ae?eicai?iiae?eai?a (o 4,8 ?ace; ?0,001). O ne?iaaooe? e?ia?,
a?aeiia?aeii, ca?eueooaaany ai?no n?aeiaeo eeneio (a 1,4 ?ace; ?0,001),
ae?eicai?iiae?eai?a (a 1,6 ?ace; ?0,001), a ??aaiue ae?eii?ioa?ae?a
a??ia?aeii ia ci?ieany (?0,05).

O iiaeaeueoiio (7-a aeiaa caoai?thaaiiy) a neiia?aeuei?e ??aeei?
cieceany ??aaiue n?aeiaeo eeneio (ia 13%; ?0,001) oa ca?eueoeany –
ae?eicai?iiae?eai?a (ia 17%; ?0,001), ii??aiyii c iiia?aaei?ie
aeine?aeaeaiiyie. O ne?iaaooe? e?ia? ciaioeany ai?no n?aeiaeo eeneio (ia
6%; ?0,05), ae?eii?ioa?ae?a (ia 18%; ?0,001), a ai?no
ae?eicai?iiae?eai?a ii?iae?coaaany (?0,05).Ia 11-o aeiao caoai?thaaiiy,
ii??aiyii c? caei?iaeie oaa?eiaie, o neiia?aeuei?e ??aeei? oai?eo oaa?ei
aoa aeuei oi?no n?aeiaeo eeneio (o 16 ?ac?a; ?0,001), ae?eii?ioa?ae?a (o
2,6 ?ace; ?0,001) ? ae?eicai?iiae?eai?a (o 6,4 ?ace; ?0,001). O
ne?iaaooe? e?ia?, a?aeiia?aeii, aoa aeuei oi?no ae?eii?ioa?ae?a (a 1,4
?ace; ?0,001), ae?eicai?iiae?eai?a (a 1,3 ?ace; ?0,001) oa n?aeiaeo
eeneio (a 1,1 ?ace; ?0,05).

Oaaeeoey 2

Ai?no a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa ne?iaaooe?
e?ia? i?e aenia?eiaioaeueieo anaioe/ieo
a?o?eoao

IieacieeeCaei?ia? Aeiaa
caoai?thaaiiyOaa?eie 3-y 7-a 11-aN?aeia?
e-oe, iaeeieoeue Aanna211,25 8,80

8,25 1,42288,32 5,59

210,73 4,70272,38 4,63

183,40 5,03234,69 5,93

128,33 4,61Ae?eii?ioa?aee, ia/e395,00 31,06

123,13 12,18428,27 16,01*

561,76 18,78353,27 10,74*

591,23 11,43563,46 16,33

316,75 15,51Ae?eicai?iiae?eaie, ia/e556,73 24,43

41,06 2,12866,11 29,61

196,64 3,07568,75 15,04*

230,00 5,01703,37 16,13

262,57 5,88I?ei?oea. 1. *enaeueiee — ne?iaaoea e?ia?, ciaiaiiee —
neiia?aeueia ??aeeia.

2. * ?0,05, ii??aiyii c ee?i?/ii caei?iaeie
oaa?eiaie.

Ci?ie ?aooe iieaciee?a a??ia?aei?.

O a?aeaeaeaiee a?ae ii/aoeo caoai?thaaiiy oa?i?i (45-a aeiaa) o
aeaeoaeaeeo ia oeae /an oaa?ei ?, iniaeeai, oai?eo ia o?ii?/iee
o?a?iceo, aoa i?aeaeuaiee oi?no n?aeiaeo eeneio (a?aeiia?aeii 21,675,45
iae. Aanna; ?0,05 oa 121,6716,00 iae. Aanna; ?0,001), ae?eii?ioa?ae?a
(302,0516,92 oa 46528,79 ia/e; ?0,001) ? ae?eicai?iiae?eai?a (56,922,89
oa 157,438,18 ia/e; ?0,001), ii??aiyii c ee?i?/ii caei?iaeie.

Oaeei /eiii, i?e aenia?eiaioaeueiiio anaioe/iiio a?o?eo? a neiia?aeuei?e
??aeei? i?aeaeuo?oueny ai?no n?aeiaeo eeneio ? ae?eii?ioa?ae?a ye
oaeoi??a ianiaoeeo?/iiai caoenoo i?aai?cio ia ii/aoeo caoai?thaaiiy,
iaeiae cieaeo?oueny c iiaeaeueoei eiai ia?aa?aii. ??aaiue aeano?oeoeaieo
yaeu o noaeia? (ai?no ae?eicai?iiae?eai?a) ?noioii i?aeaeuo?oueny ia
ii/aoeo caoai?thaaiiy ? caeeoa?oueny ia aenieiio ??ai? c iiaeaeueoei
eiai ia?aa?aii. Aeaeoaeaiiy oaa?ei noi?iaiaeaeo?oueny iaiaaeaiiyi
aeano?oeoeaieo yaeu o noaeia? i?e i?aeaeuaiiio ai?no? oaeoi??a
ianiaoeeo?/iiai caoenoo a neiia?aeuei?e ??aeei?.

IAA?OIOOAAIIss CANOINOAAIIss 15%-IIAI ?IC*EIO IIE?A?I?EI??IE?AeIIO C
A?Ae?IEI?OECIIII OA E?AeIEA?III I?E AENIA?EIAIOAEUeIEO ANAIOE*IEO
A?O?EOAO O IIEIAeIssEO AAEEEI?

?IAAOI? OOAeIAE

Ee?i?ei-aaiaoieia?/i? ci?ie i?e e?eoaaii?

I?e e?eoaaii? oai?? oaa?eie aeine?aeii? a?oie aaea ia 2–3-th aeiao i?ney
?i’?eoe?? iaee caaeia?eueiee caaaeueiee noai, a iieacieee caaaeueii?
oaiia?aoo?e o?ea, /anoioe ioeueno oa aeeoaiiy eieeaaeenue o iaaeao
ii?ie. Iie?aueeanue ?ooiaa aeoeai?noue oaa?ei. Niinoa??aaeenue
eoeueaaa?noue ii??ii? e?ioe?aee iecueeiai nooiaiy i?ae /an ?ooo oa
ei?ioei/ania iiaia iie?aiiy o niiei?. Ianeai? ?ooe cia/ii? aiie?ooaee
aeeeeeaee a?eue. Ciaioeany ia’?i oai?iai noaeiaa, eiai eiioo?e noaee
a?eueo ae?acieie. O ae?eyioe? noaeiaa aeyaeyee iaiaaeaia, ou?eueiaia,
iacia/ii aieth/a, c ia?noioiei i?aeaeuaiiyi i?noeaai? oaiia?aoo?e
i?eiooaiiy oeaiei. Neiia?aeuei? aeai?ioe noaeiaa aoee a?ae/ooi? ?
oeoeooth/?.

Ia 4–5-o aeiao e?eoaaiiy niinoa??aaee ?noioia iie?auaiiy caaaeueiiai
noaio oaa?ei, a?aenooi?noue eoeueaaaino? i?ae /an ?ooo oa iiaia iie?aiiy
oai?ith e?ioe?aeith o niiei?. Ciaioeany ia’?i ooeiaeaeaiiai noaeiaa, a
eiai ae?eyioe? aoei iaiaaeaia, ou?eueiaia, aacaie?nia ? aac i?aeaeuaiiy
i?noeaai? oaiia?aoo?e i?eiooaiiy oeaiei. Eiioo?e neiia?aeueieo aeai?io?a
ia a?ae??ciyeenue a?ae caei?iaiai noaeiaa, aoee oeoeooth/?, i?e ?o
ioieoe?? aeae?eyeanue aeinoaoiy e?euee?noue a’ycei?, aea aeaui iooii?,
nieii’yii-aeiaoiai eieuei?o neiia?aeueii? ??aeeie.

O oaa?ei eiio?ieueii? a?oie iie?auaiiy noaio a?aeaoeiny eeoa ia 4– 5-o
aeiao e?eoaaiiy, aea /anoei? c ieo (27%) i?iaiaeeee iiaoi?io
aioo??oiueinoaeiaiao ?i’?eoe?th. Ee?i?/ia aeaeoaeaiiy oaa?ei
eiio?ieueii? a?oie a?aeaoeiny ia 7– 8-o aeiao e?eoaaiiy.

Oaeei /eiii, aioo??oiueinoaeiaiaa aaaaeaiiy 10–15 ie 15%-iiai ?ic/eio
iie?a?i?ei??ie?aeiio, 2 ie (50 ia) noniaic?? a?ae?iei?oeciio aoeaoaoo, 1
ie 10%-iiai ?ic/eio e?aeiea?io oa 1 ie 4%-iiai ?ic/eio aaioai?oeeio
noeueoaoo aeicaiey? ia 2–4 aeiae nei?ioeoe oa?i?i e?eoaaiiy oai?eo ia
anaioe/iee a?o?eo oaeyo, ii??aiyii c o?aaeeoe?eiei iaoiaeii –
aioo??oiueinoaeiaiaei aaaaeaiiyi 5–6 ie (125–150 ia) noniaic??
a?ae?iei?oeciio aoeaoaoo ia 10 ie 0,5%-iiai ?ic/eio iiaiea?io, 1 ie
4%-iiai ?ic/eio aaioai?oeeio noeueoaoo.

Ia 9-o aeiao e?eoaaiiy, ii??aiyii c? caei?iaeie oaa?eiaie, o e?ia? o
e?ia? oai?eo aoa ieae/ee ??aaiue a?eo?ioeeo?a (a 1,3 ?ace a aeine?aei?e;
?0,01 oa a 1,5 ?ace – o eiio?ieuei?e; ?0,001), eaeeioeeo?a
(a?aeiia?aeii a 1,2 ?ace; ?0,05 oa a 1,4 ?ace; ?0,01), aaiiaeia?io (a
1,3 ?ace; ?0,05 oa a 1,4 ?ace; ?0,001). O eaeeia?ai? aoa cia/ii a?eueoee
a?aenioie thieo (1,520,18 oa 2,480,19%; ?0,001) ? iaee/eiyaea?ieo
iaeo?io?e?a (a 1,7 ?ace a iaio a?oiao; ?0,001), iiiioeeo?a (ia 0,75% a
aeine?aei?e; ?0,05), aiceiio?e?a (a 1,6 ?ace o eiio?ieuei?e; ?0,05),
ieae/ee oi?no naaiaioiyaea?ieo iaeo?io?e?a (ia 2,48% o eiio?ieuei?e;
?0,001), e?ioioeeo?a (ia 4,82 oa 4,43%; ?0,001).

Ioaea, o oaa?ei aeine?aeii? a?oie ii?yae c ee?i?/iei iaeoaeaiiyi
a?aeaoaaeinue a?eueo oaeaeea a?aeiiaeaiiy ii?oieia?/iiai neeaaeo e?ia?,
i?ae o eiio?ieuei?e a?oi? oaa?ei.

Ci?ie ai?noo caaaeueiiai a?eea ? eiai o?aeoe?e o neiia?aeuei?e ??aeei?
oa ne?iaaooe? e?ia? i?e e?eoaaii?

Ia 5-o aeiao e?eoaaiiy, ii??aiyii c iieacieeaie aei eiai i?iaaaeaiiy,
i?aeaeueany ??aaiue caaaeueiiai a?eea o neiia?aeuei?e ??aeei? oaa?ei
aeine?aeii? (ia 26%; ?0,001) oa eiio?ieueii? (ia 28%; ?0,001) a?oie.

O neiia?aeuei?e ??aeei? oaa?ei aeine?aeii? a?oie ca?eueoeany ai?no
aeueaoi?i?a (ia 2,83%; ?0,05), oea?oeiieaci?io (a 1,6 ?ace; ?0,001),
aenieei caeeoaany ai?no o?ainoa?ei?a, aaioiaeia?i?a. A?aeiiaeany aei
iieaciee?a o caei?iaeo oaa?ei ai?no -aeiaoe?i?a, ?noioii ciaioeeanue
ieoiia aaaa Ig G (ia 6,48%; ?0,001) ? a?ee?a S-o?aeoe?? (a 1,4 ?ace;
?0,001). O oaa?ei eiio?ieueii? a?oie, a?aeiia?aeii, ca?eueoeany ai?no
oea?oeiieaci?io (a 1,4 ?ace; ?0,05), o?ainoa?ei?a (ia 1,7%; ?0,01), ia
aenieiio ??ai? caeeoaany ai?no aaioiaeia?i?a, ?noioii ciaioeeanue ieoiia
aaaa Ig G (ia 5,91%; ?0,001).

Oaaeeoey 3

Ai?no caaaeueiiai a?eea o ne?iaaooe? e?ia? oa neiia?aeuei?e ??aeei? i?e
e?eoaaii? anaioe/iiai a?o?eoo , a/e

??aeeie i?aai?cioCaei?ia? oaa?eieOai?? oaa?eieAeiaa
e?eoaaiiy5-a9-aNe?iaaoea e?ia?66,02 ± 1,50 73,13 ± 0,5675,08 ± 0,91

75,45 ± 0,82 69,37 ± 0,49

70,25 ± 1,60 *Neiia?aeueia ??aeeia11,45 ± 0,6755,47 ± 1,23 69,85 ±
0,93

70,96 ± 1,24 54,00 ± 0,66

57,50 ± 2,39 I?ei?oea. 1. *enaeueiee – aeine?aeia, ciaiaiiee –
eiio?ieueia a?oie.

2. * ?0,05, ii??aiyii c ee?i?/ii caei?iaeie
oaa?eiaie.

Ci?ie ?aooe iieaciee?a a??ia?aei?.

O ne?iaaooe? e?ia? a oeae ia??iae oaeiae i?aeaeueany ai?no caaaeueiiai
a?eea ia 3% a aeine?aei?e ( ?0,05) oa eiio?ieuei?e ( ?0,05) a?oiao. I?e
oeueiio o oaa?ei aeine?aeii? a?oie i?aeaeueany ai?no i?aaeueaoi?i?a (a
1,9 ?ace; ?<0,001), Ig G (ia 1,5%; ?0,01), A (a 1,5 ?ace; ?0,001), oea?oeiieaci?io (a 1,6 ?ace; ?0,001), caeeoeany i?aeaeuaiei oi?no o?ainoa?ei?a, aaioiaeia?i?a, cieceany ai?no aeueaoi?i?a (a 1,3 ?ace; ?0,001), -aeiaoe?i?a (ia 2,09%; ?0,001) oa a?ee?a S-o?aeoe?? (ia 0,82%; ?0,001). O eiio?ieuei?e a?oi?, a?aeiia?aeii, i?aeaeueany ai?no i?aaeueaoi?i?a (a 1,7 ?ace; ?0,001), Ig G (ia 2,89%; ?0,01), oea?oeiieaci?io (a 1,2 ?ace; ?0,05), o?ainoa?ei?a (a 1,2 ?ace; ?0,001), caeeoaany i?aeaeuaiei oi?no aaioiaeia?i?a, cieceany ai?no aeueaoi?i?a (a 1,4 ?ace; ?0,001). O iiaeaeueoiio, ia 9-o aeiao e?eoaaiiy, oi?no caaaeueiiai a?eea o neiia?aeuei?e ??aeei? oaa?ei iaio a?oi ciaioeany, aea, ii??aiyii c? caei?iaeie, caeeoaany ?noioii aeuei o aeine?aei?e (o 4,7 ?ace; ?<0,001) oa eiio?ieuei?e (o 5 ?ac?a; ?<0,001) a?oiao. I?e oeueiio a aeine?aei?e a?oi? aoa cia/ii aeuee ??aaiue oea?oeiieaci?io (o 2,6 ?ace; ?0,001), o?ainoa?ei?a (ia 2,58%; ?0,001), aaioiaeia?i?a (ia 2,9%; ?0,001), Ig G (ia 2,46%; ?0,05), A (o 2 ?ace; ?0,001) oa ieae/ee oi?no aeueaoi?i?a (a 1,8 ?ace; ?0,001), ii??aiyii c? caei?iaeie oaa?eiaie, uiaei ?ioeo o?aeoe?e ci?ie aoee iaa??ia?aeieie (?0,05). O oaa?ei eiio?ieueii? a?oie, a?aeiia?aeii, niinoa??aaee aeuee ??aaiue i?aaeueaoi?i?a (a 1,4 ?ace; ?0,001), oea?oeiieaci?io (o 2,3 ?ace; ?0,001), o?ainoa?ei?a (ia 2,36%; ?0,01), aaioiaeia?i?a (ia 3,64%; ?0,001), Ig G (ia 3,82%; ?0,001), A (a 1,8 ?ace; ?0,001), ieae/ee ai?no aeueaoi?i?a (o 2 ?ace; ?0,001). O ne?iaaooe? e?ia? a oeae ia??iae oaeiae ciaioeany ai?no caaaeueiiai a?eea o oaa?ei iaio a?oi. I?e oeueiio o aeine?aei?e a?oi? aoa aeuee ai?no oea?oeiieaci?io (a 1,9 ?ace; ?0,001), o?ainoa?ei?a (ia 2,05%; ?0,001), aaioiaeia?i?a (ia 1,15%; ?0,001) ? ieae/ee– -aeiaoe?i?a (a 1,3 ?ace; ?0,001), Ig G (ia 2,18%; ?0,05), ii??aiyii c? caei?iaeie oaa?eiaie. O oaa?ei eiio?ieueii? a?oie, a?aeiia?aeii, niinoa??aaee aeuee oi?no i?aaeueaoi?i?a (ia 0,95%; ?0,01), oea?oeiieaci?io (a 1,9 ?ace; ?0,001), aaioiaeia?i?a (ia 1,89%; ?0,001), iacia/ii i?aeaeuaiee– o?ainoa?ei?a (ia 1,03%; ?0,05) oa ieae/ee– aeueaoi?i?a (ia 3,52%; ?0,001), Ig G (ia 2,08%; ?0,001), a?ee?a S-o?aeoe?? (ia 0,65%; ?0,01), -aeiaoe?i?a (ia 1,88%; ?0,001). Oaeei /eiii, i?e e?eoaaii? oaa?ei iaio a?oi o neiia?aeuei?e ??aeei? i?aeaeuo?oueny ai?no a?ee?a aino?i? oace ye oaeoi??a ianiaoeeo?/iiai caoenoo i?aai?cio, ?ia?a?oi?iee iioaioe?ae neiia?aeueii? ??aeeie oa iaiaaeo?oueny i?iieei?noue neiia?aeueii? iaieiiee aeey aenieiiieaeoey?ieo a?ee?a. Ci?ie ai?noo a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? i?e e?eoaaii? Ia 5-o aeiao e?eoaaiiy o neiia?aeuei?e ??aeei? oaa?ei iaio a?oi niinoa??aaee ?noioia i?aeaeuaiiy ai?noo n?aeiaeo eeneio (ia 11% a aeine?aei?e; ?0,05 oa ia 21% o eiio?ieuei?e; ?0,001) ? ae?eii?ioa?ae?a (a?aeiia?aeii a 1,6 oa 1,7 ?ace; ?0,001). O aeine?aei?e a?oi? ai?no ae?eicai?iiae?eai?a cieceany ia 20% (?0,001), o eiio?ieuei?e – ia 47% (?0,001), ui coiiaeaii canoinoaaiiyi a?ae?iei?oeciio o aaeee?e e?eueeino?. O oeae /an o ne?iaaooe? e?ia? oaa?ei aeine?aeii? a?oie i?aeaeueany ai?no n?aeiaeo eeneio (ia 10%; ?0,05), ae?eii?ioa?ae?a (ia 44%; ?0,05), o eiio?ieuei?e – ciaioeany ai?no ae?eii?ioa?ae?a (ia 17%; ?0,05) oa ?noioii ia ci?ieany ai?no n?aeiaeo eeneio (303,0018,39 i?ioe 288,325,59 iae. Aanna o oai?eo; ?0,05). I?ioa o oaa?ei iaio a?oi cieceany ai?no ae?eicai?iiae?eai?a (ia 18% a aeine?aei?e; ?0,001 oa ia 30% o eiio?ieuei?e; ?0,001). O iiaeaeueoiio cieceany ai?no n?aeiaeo eeneio ? ae?eii?ioa?ae?a o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? oaa?ei iaio a?oi. Ia 9-o aeiao e?eoaaiiy, ii??aiyii c? caei?iaeie oaa?eiaie, o neiia?aeuei?e ??aeei? oai?eo oaa?ei iaio a?oi aoa aeuee oi?no n?aeiaeo eeneio (212,007,00 iae. Aanna o aeine?aei?e oa 224,139,00 o eiio?ieuei?e; ?0,001) ? ae?eii?ioa?ae?a (a?aeiia?aeii 800,12 28,62 ia/e; ?0,001 oa 727,50 11,77 ia/e; ?0,001). O ne?iaaooe? e?ia?, a?aeiia?aeii, oaeiae aoa aeuee oi?no n?aeiaeo eeneio (260,006,98 iae. Aanna a aeine?aei?e oa 276,365,71 o eiio?ieuei?e; ?0,001), a ??aaiue ae?eii?ioa?ae?a aoa ieae/ei o aeine?aei?e a?oi? (233,84 13,20 ia/e i?ioe 395,00 31,06; ?0,05) ? a??ia?aeii ia a?ae??ciyany o eiio?ieuei?e (?>0,05).

Oaaeeoey 4

Ai?no ae?eicai?iiae?eai?a o ne?iaaooe? e?ia? oa neiia?aeuei?e ??aeei?
i?e e?eoaaii? anaioe/iiai a?o?eoo, ia/e

??aeeie i?aai?cioCaei?ia? oaa?eieOai?? oaa?eie Aeiaa
e?eoaaiiy5-a9-aNe?iaaoea e?ia?556,73 ± 24,43866,11 ± 29,61 711,54 ±17,27

606,99 ±35,95 * 625,38 ±13,30

804,20 ± 2 8,91 Neiia?aeueia ??aeeia 41,06 ± 2,12 196,64 ± 3,07
156,77 ± 6,43

104,62 ±3,94 113,23 ± 5,96

156,15 ± 2,88 I?ei?oea. 1. *enaeueiee – aeine?aeia, ciaiaiiee –
eiio?ieueia a?oie.

2. * ?0,05, ii??aiyii c ee?i?/ii caei?iaeie
oaa?eiaie.

Ci?ie ?aooe iieaciee?a a??ia?aei?.

Ai?no ae?eicai?iiae?eai?a i?iaeiaaeoaaa aeeiai?/ii cieaeoaaoenue o
aeine?aei?e a?oi?, aea caeeoaany cia/ii aeuei, i?ae o caei?iaeo oaa?ei
(o 2,8 ?ace o neiia?aeuei?e ??aeei?; ?<0,001 oa ia 12% – o ne?iaaooe? e?ia?; ?0,05). O eiio?ieuei?e a?oi? ?o oi?no ca?eueoeany (?0,001) ? aoa aeuei a?ae iieaciee?a caei?iaeo oaa?ei (?0,001) ? oaa?ei aeine?aeii? a?oie (?<0,001) ye o neiia?aeuei?e ??aeei?, oae ? a ne?iaaooe? e?ia?. Oaeei /eiii, i?e e?eoaaii? aenia?eiaioaeueieo anaioe/ieo a?o?eo?a o neiia?aeuei?e ??aeei? oaa?ei iaio a?oi i?aeaeuo?oueny ai?no n?aeiaeo eeneio oa ae?eii?ioa?ae?a ye oaeoi??a ianiaoeeo?/iiai caoenoo i?aai?cio. Aea o aeine?aei?e a?oi? ai?no ae?eicai?iiae?eai?a cia/ii ieae/ee, ui na?ae/eoue i?i a?eueo ?aii? ? aeeiai?/ia iaiaaeaiiy aeano?oeoeaieo yaeu o noaeia?. AENIIAEE 1. Na?aae o??o?a?/ieo caoai?thaaiue e?ioe?aie o aaeeei? ?iaaoi? ooaeiae a?o?eoe noaiiaeyoue 19,9%. 2. Aenia?eiaioaeuei? a?o?eoe, aeeeeeai? ia oii? nainea?e?caoe??, oa?aeoa?ecothoueny a?ia?a?a?/iei oeiii caiaeaiiy ? o?eaaeei eiai ia?aa?aii i?e iaya- iino? aeeoociiai, aa?y/iai ? aieth/iai i?eiooaiiy oeaiei o ae?eyioe? noaeiaa oa na?icii-o?a?eiiciiai aeiioo a eiai ii?iaeieio. 3. Neiia?aeueia ??aeeia ee?i?/ii caei?iaiai iieiaeiyeo aaeeei? ?iaaoi? ooaeiae i?noeoue caaaeueiee a?eie (11,45±0,67 a/e) oa ianooii? eiai o?aeoe?? (%): i?aaeueaoi?ie – 2,86±0,26; aeueaoi?ie – 40,21±1,61; -aeiaoe?ie – 15,58±0,50; oea?oeiieaci?i – 3,70±0,27; o?ainoa?eie – 6,22±0,22; aaioiaeia?ie – 7,00±0,20; Ig G – 15,27±0,59; A – 5,22±0,27; a?eee S-o?aeoe?? – 3,94±0,26. Aei ?? neeaaeo aoiaeyoue n?aeia? eeneioe – 8,25±1,42 iae. Aanna, ae?eii?ioa?aee – 123,13±12,18 ia/e, ae?eicai?iiae?eaie – 41,06±2,12 ia/e. 4. Anaioe/i? a?o?eoe o ae/e?a ia ?aii?o noaae?yo noi?iaiaeaeothoueny i?aeaeuaiiyi oi?noo caaaeueiiai a?eea o neiia?aeuei?e ??aeei? (o 4,9 ?ace; ?<0,001) oa ne?iaaooe? e?ia? (a 1,1 ?ace; ?<0,001). 5. C ?icaeoeii anaioe/iiai caiaeaiiy noaeiaa o neiia?? a??ia?aeii i?aeaeuo?oueny ai?no Ig G (a 1,8 ?ace), A (a 1,6 ?ace), oea?oeiieaci?io (a 1,6 ?ace), o?ainoa?ei?a (a 1,2 ?ace), aaioiaeia?i?a (a 1,2 ?ace) i?e iaeii/aniiio ciaioaii? ai?noo aeueaoi?i?a (a 1,9 ?ace) oa -aeiaoe?i?a (ia 1,85%). O iiaeaeueoiio (ia 7-11-o aeiao) i?iaeiaaeo? cieaeoaaoenue ai?no aeueaoi?i?a, -aeiaoe?i?a, a?ee?a aino?i? oace (?<0,05) i?e a??ia?aeiiio i?aeaeuaii? Ig G, A, a?ee?a S-o?aeoe?? oa i?aaeueaoi?i?a (?<0,001). 6. O oai?eo oaa?ei ia ii/aoeo caiaeueiiai i?ioeano niinoa??aa?oueny c?inoaiiy ai?noo n?aeiaeo eeneio o ne?iaaooe? e?ia? (aei 288,32±5,59 iae. Aanna i?e ii?i? 211,25±8,80; ?<0,001) ?, iniaeeai, o neiia?aeuei?e ??aeei? (aei 210,73±4,70 iaeeieoeue Aanna; ?<0,001). O iiaeaeueoiio (ia 11-o aeiao caoai?thaaiiy) a?aeaoaa?oueny aeeiai?/ia cieaeaiiy ai?noo n?aeiaeo eeneio ye o ne?iaaooe? e?ia? (aei 234,69±5,93 iae. Aanna; ?<0,001), oae ? a neiia?aeuei?e ??aeei? (aei 128,3±4,61iae. Aanna; ?<0,001). 7. Ia ii/aoeo ?icaeoeo anaioe/iiai a?o?eoo o neiia?aeuei?e ??aeei? a?aeaoaa?oueny i?aeaeuaiiy ai?noo ae?eii?ioa?ae?a (aei 561,76±18,78 oa 591,23±11,43 ia/e ia 3-th ? 7-o aeiao caoai?thaaiiy; ?<0,001) oa ?o cieaeaiiy o iiaeaeueoiio (aei 316,75±15,51 ia/e ). O ne?iaaooe? e?ia? ?o i?aeaeuaiiy (aei 563,46±16,33 ia/e; ?<0,001) ?a?no?o?oueny eeoa ia 11-o aeiao caoai?thaaiiy. 8. Caiaeueiee i?ioean o noaeia? ae/e?a oa?aeoa?eco?oueny a??ia?aeiei i?aeaeuaiiyi ai?noo ae?eicai?iiae?eai?a o neiia?? (a?ae 196,64±3,07 ia/e ia 3-th aeiao aei 262,57±5,88 ia 11-o; ?<0,001 ), oiae? ye o ne?iaaooe? e?ia? iaeaeuee ?o oi?no niinoa??aaee ia ii/aoeo caoai?thaaiiy (866,11±29,61 ia/e i?e ii?i? 556,73±24,43; ?<0,001). 9. E?eoaaiiy oaeyo c anaioe/iei a?o?eoii oeyoii ?i’?eoe?? o ii?iaeieio noaeiaa 10– 15 ie 15%-iiai ?ic/eio iie?a?i?ei??ie?aeiio, 2 ie (50 ia) noniaic?? a?ae?iei?oeciio aoeaoaoo, 1 ie 10%-iiai ?ic/eio e?aeiea?io a?ae?ioei?eaeo ? 1 ie 4%-iiai ?ic/eio aaioai?oeeio noeueoaoo aeicaiey? nei?ioeoe oa?i?i aeaeoaeaiiy oai?eo oaa?ei ia 2-4 aei?, ii??aiyii c o?aaeeoe?eiei iaoiaeii (?<0,001). 10. E?eoaaeueia aoaeoeai?noue aeei?enoaieo cania?a ni?ey? ii?iae?caoe?? ia?aa?ao caiaeueii? ?aaeoe??, ca?eueoaiith o neiia?aeuei?e ??aeei? ai?noo caaaeueiiai a?eea, oea?oeiieaci?io, o?ainoa?ei?a, aaioiaeia?i?a (?<0,001), a?aeiiaeaiith ??aiy -aeiaoe?i?a i?e ?noioiiio ciaioaii? Ig G oa a?ee?a S-o?aeoe??. 11. Canoinoaaiiy cai?iiiiiaaiiai iaoiaeo e?eoaaiiy noi?iaiaeaeo?oueny i?aeaeuaiiyi o neiia?aeuei?e ??aeei? ai?noo n?aeiaeo eeneio (c 210,73±4,7 aei 234,0±8,19 ie. Aanna; ?<0,05), ae?eii?ioa?ae?a (c 561,76±18,78 aei 927,85± 53,56 ia/e; ?<0,001) oa aeeiai?/iei cieaeaiiyi oi?noo ae?eicai?iiae?eai?a (c 196,64±3,07 aei 113,23±5,96 ia/e; ?<0,001) ia oii? iaiaaeaiiy aeano?oeoeaieo i?ioean?a o noaeia?. I?IIICEOe?? AE?IAIEOeOAO Aeey e?eoaaiiy oaeyo c anaioe/ieie na?icii-o?a?eiicieie a?o?eoaie i?iiiio?ii i?ney nii?iaeiyth/i? ioieoe?? noaeiaa aaiaeeoe a iueiai 10–15 ie 15%-iiai ?ic/eio iie?a?i?ei??ie?aeiio, 2 ie (50 ia) noniaic?? a?ae?iei?oeciio aoeaoaoo, 1 ie 10%-iiai ?ic/eio e?aeiea?io a?ae?ioei?eaeo ? 1ie 4%-iiai ?ic/eio aaioai?oeeio noeueoaoo c ?ioa?aaeii 3– 4 aeiae aei ee?i?/iiai aeaeoaeaiiy. NIENIE INIIAIEO I?AOeUe, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. *i?iicoa I. I. Ai?no ae?eii?ioa?ae?a o neiia?aeuei?e ??aeei? iieiaeiyeo aaeeei? ?iaaoi? ooaeiae // A?niee A?eioea?e?a. aea?ae. aa?a?. oi-oo. – Aei. 3. – *. 1. – A?ea Oea?eaa, 1997. – N. 167 – 169. 2. ?caeainueeee A. E., *i?iicoa I. I. Iniaeeaino? iai?io ae?eii?ioa?ae?a ne?iaaoee e?ia? oa neiia?aeueii? ??aeeie i?e anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae // A?niee A?eioea?e?a. aea?ae. aa?a?. oi-oo. – Aei. 5. – *. 2. – A?ea Oea?eaa, 1998. – N. 164 – 169. 3. *i?iicoa I. I., ?caeainueeee A. E. Aoaeoeai?noue aeayeeo iaoiae?a e?eoaaiiy anaioe/ieo a?o?eo?a o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae // A?niee A?eioea?e?a. aea?ae. aa?a?. oi-oo. – Aei. 7. – *. 1. – A?ea Oea?eaa, 1998. – N. 91 – 95. 4. *i?iicoa I. I., ?euei?oeueeee I. A. A?eeiaee iai?i o ne?iaaooe? e?ia? oa neiia?aeuei?e ??aeei? i?e anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae // A?niee A?eioea?e?a. aea?ae. aa?a?. oi-oo. – Aei. 7. – *. 1. – A?ea Oea?eaa, 1998. – N. 95 – 100. 5. *i?iicoa I. I. Ci?ie ai?noo a?eea oa eiai o?aeoe?e o neiia?aeuei?e ??aeei? iieiaeiyeo aaeeei? ?iaaoi? ooaeiae i?e e?eoaaii? anaioe/ieo a?o?eo?a // A?niee A?eioea?e?a. aea?ae. aa?a?. oi-oo. – Aei. 8. – *. 1. – A?ea Oea?eaa, 1999. – N. 265–270. *i?iicoa I. I. Ci?ie a?ee?a ? a?eeiai-aoaeaaiaeieo niieoe o neiia?aeuei?e ??aeei? oa ne?iaaooe? e?ia? i?e anaioe/ieo a?o?eoao o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae (ee?i?ei-aenia?eiaioaeuei? aeine?aeaeaiiy). – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa aaoa?eia?ieo iaoe ca niaoe?aeuei?noth 16.00.05 – aaoa?eia?ia o??o?a?y. – A?eioea?e?anueeee aea?aeaaiee aa?a?iee oi?aa?neoao, A?ea Oea?eaa, 1999. Aeena?oaoe?y i?enay/aia aea/aiith ?ie? aeayeeo iieaciee?a neiia?aeueii? ??aeeie a iaoiaaiac? anaioe/ieo a?o?eo?a o iieiaeiyeo aaeeei? ?iaaoi? ooaeiae ? ii?aoethaaiith ia oe?e iniia? iaoiaaiaoe/ii iaa?oioiaaieo iaoiae?a e?eoaaiiy. Aea/aii ai?no a?ee?a aino?i? oace – oea?oeiieaci?io, o?ainoa?ei?a, aaioiaeia?i?a, a oaeiae n?aeiaeo eeneio, ae?eii?ioa?ae?a ? ae?eicai?iiae?eai?a o neiia?aeuei?e ??aeei? ee?i?/ii caei?iaiai iieiaeiyeo aaeeei? ?iaaoi? ooaeiae oa ?o ci?ie a aeeiai?oe? aenia?eiaioaeueiiai anaioe/iiai a?o?eoo. Iaea?aeai? ?acoeueoaoe aeine?aeaeaiue aeaee ciiao ii?aoethaaoe ? ?aeiiaiaeoaaoe ae?iaieoeoao iaoiae e?eoaaiiy, yeee aeineoue oaeaeei iaiaaeo? aeoeai?noue caiaeueii? ?aaeoe?? a noaeia? ? aeicaiey? ?noioii nei?ioeoe oa?i?i e?eoaaiiy oai?eo oaa?ei. *i?iicoa I. I. Eciaiaiey aaeeia e aaeeiai-oaeaaiaeiuo niaaeeiaiee a neiiaeaeueiie aeeaeeinoe e nuai?ioea e?iae i?e anaioe/aneeo a?o?eoao o iieiaeiyea e?oiiiai ?iaaoiai neioa (eeeieei-yenia?eiaioaeueiua enneaaeiaaiey). – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/?iie noaiaie eaiaeeaeaoa aaoa?eia?iuo iaoe ii niaoeeaeueiinoe 16.00.05 – aaoa?eia?iay oe?o?aey. – Aaeioea?eianeee ainoaea?noaaiiue aa?a?iue oieaa?neoao, Aaeay Oea?eiaue, 1999. Aeenna?oaoeey iinayuaia eco/aieth ?iee iaeioi?uo iieacaoaeae neiiaeaeueiie aeeaeeinoe a iaoiaaiaca anaioe/aneeo a?o?eoia o iieiaeiyea e?oiiiai ?iaaoiai neioa e ?ac?aaioea ia yoie iniiaa iaoiaaiaoe/anee iainiiaaiiuo iaoiaeia ea/aiey. Eco/aii niaea?aeaiea aaeeia ino?ie oacu – oea?oeiieacieia, o?ainoa??eiia, aaioiaeiaeiia, a oaeaea neaeiauo eeneio, aeeeii?ioaeaeia e aeeeicaieiiaeeeaiia a neiiaeaeueiie aeeaeeinoe eeeie/anee caei?iaiai iieiaeiyea e?oiiiai ?iaaoiai neioa. Onoaiiaeaii, /oi neiiaeaeueiay aeeaeeinoue eeeie/anee caei?iauo oaeyo niaea?aeeo iauee aaeie (11,45 0,67 a/e) e neaaeothuea aai o?aeoeee (%): i?aaeueaoieiu– 2,860,26; aeueaoieiu– 40,211,61; -aeiaoeeiu – 15,580,50; oea?oeiieaciei – 3,700,27; o?ainoa??eiu – 6,220,22; aaioiaeiaeiu – 7,000,20; Ig G – 15,270,59; A – 5,220,27; aaeee S-o?aeoeee – 3,940,26. A ninoaa neiiaeaeueiie aeeaeeinoe aoiaeyo neaeiaua eeneiou – 8,251,42 aae. Aanna, aeeeii?ioaeaeu – 123,1312,18 ia/e e aeeeicaieiiaeeeaiu – 41,062,12 ia/e. Eco/aiu oaeaea eciaiaiey niaea?aeaiey oeacaiiuo iieacaoaeae neiiaeaeueiie aeeaeeinoe a aeeiaieea yenia?eiaioaeueiuo anaioe/aneeo a?o?eoia o iieiaeiyea e?oiiiai ?iaaoiai neioa. Onoaiiaeaii, /oi niaea?aeaiea aaeeia ino?ie oacu, neaeiauo eeneio e aeeeii?ioaeaeia eae oaeoi?ia ianiaoeeoe/aneie caueou i?aaiecia aic?anoaao a ia/aea ainiaeeoaeueiiai i?ioeanna a nonoaaa, ii nieaeaaony n iineaaeothuei aai oa/aieai. O?iaaiue aeano?oeoeaiuo yaeaiee a nonoaaa (niaea?aeaiea aeeeicaieiiaeeeaiia) cia/eoaeueii iiauoaaony a ia/aea caaieaaaiey e inoaaony aeinoaoi/ii aunieei aeeeoaeueiia a?aiy. Iieo/aiiua ?acoeueoaou enneaaeiaaiee iicaieeee ?ac?aaioaoue iaoiae ea/aiey i?e anaioe/aneeo a?o?eoao, eioi?ue caeeth/aaony ai aioo?enonoaaiii aaaaeaiee 10–15 ie 15%-iiai ?anoai?a iieeaeieeie??ieeaeiia (eneonnoaaiiiai caiaieoaey neiiaeaeueiie aeeaeeinoe) n 2 ie (50 ia) noniaicee aeae?iei?oeciia aoeaoaoa, 1 ie 10%-iiai ?anoai?a eeaeieaeia e 1 ie 4%-iiai ?anoai?a aaioaieoeeia noeueoaoa. Onoaiiaeaii, /oi i?e oaeii ea/aiee eeeie/aneia aucaei?iaeaiea aeeaioiuo i?ienoiaeeo ia 4– 5-e aeaiue aai i?iaaaeaiey, a oi a?aiy eae i?e o?aaeeoeeiiiuo iaoiaeao (aioo?enonoaaiia aaaaeaiea 5– 6 ie – 125–150 ia – noniaicee aeae?iei?oeciia aoeaoaoa ia 0,5%-iii iiaieaeia) – ia 7– 8-e. I?aaeeaaaaiia ea/aiea niinianoaiaaei iiauoaieth a neiiaeaeueiie aeeaeeinoe aaeeia ino?ie oacu, neaeiauo eeneio e aeeeii?ioaeaeia eae oaeoi?ia ianiaoeeoe/aneie caueou i?aaiecia i?e nieaeaiee aeeeicaieiiaeeeaiia – iieacaoaey aeano?oeoeaiuo yaeaiee. Iieo/aiiua ?acoeueoaou enneaaeiaaiee iicaieeee ?aeiiaiaeiaaoue i?iecaiaenoao aeey ea/aiey anaioe/aneeo a?o?eoia o e?oiiiai ?iaaoiai neioa aioo?enonoaaiia aaaaeaiea 10–15 ie 15%-iiai ?anoai?a iieeaeieeie??ieeaeiia n 2 ie (50 ia) noniaicee aeae?iei?oeciia aoeaoaoa, 1 ie 10%-iiai ?anoai?a eeaeieaeia aeae?ioei?eaea e 1 ie 4%-iiai ?anoai?a aaioaieoeeia noeueoaoa n eioa?aaeii 3– 4 aeiy aei eeeie/aneiai aucaei?iaeaiey. Chornozub N.P. The changes of proteins and protein-carbohydrates in synovial fluid and blood serum at aseptical arthritis in young cattle (clinical and experimental investigation). – Manuscript. The thesis for a candidates degree of veterinary sciences, specialty 16.00.05 – Veterinary Surgery. – Bila Tserkva State Agrarian University, Bila Tserkva, 1999. The dissertation is devoted to the studying the role some indices of synovial fluid in the pathogenesis of aseptical arthritis in young cattle. Using the obtained results there was developed the propriate method of the treatment of the aseptical arthritis. There were studied the acute stage protein content (ceruloplasmine, transferines, haptoglobines), the sialic acids, glicoproteids and glicosaminoglicanes in synovial fluid there were studied too. We compared the changes of the indices in synovial fluid of healthy animals and ones withe aseptical arthritis. The obtained results allow us to develop and recommend for wider using the treatment methods that normalize the activity of inflammation in joints and greatly the time of sich animals treatment.

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