3

I?I?NOA?NOAI IOI?IIE CAeI?IA”ss OE?A?IE

EE?ANUeEA IAAeE*IA AEAAeAI?ss I?NEssAeEIEIIII? INA?OE ?I. I.
E. UOIEEA

Eeeiainueea Iaeey A?eoi??aia

OAeE
616.361-002:616.342]-085.24

ACA?IICA”ssCIE NEI?I*OAAEUeII? OOIEOe?? AEIA*IIAI I?OO?A OA
II?OIEIA?*IIAI NOAIO NEECIAI? IAIEIIEE AANO?IAeOIAeAIAEUeII? CIIE

14. 01. 02- aioo??oi? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

EE?A-1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Noinueeiio aea?aeaaiiio oi?aa?neoao? I?i?noa?noaa
ina?oe Oe?a?ie.

Iaoeiaee ea??aiee:

aeieoi? iaaee/ieo iaoe, i?ioani?, I?EIANUeEEE A?EOI? OAE?ENIAE*,
Noinueeee aea?aeaaiee oi?aa?neoao I?i?noa?noaa ina?oe Oe?a?ie, eaoaae?a
oa?ai??? iaaee/iiai oaeoeueoaoo, i?ioani? eaoaae?e.

Io?oe?ei? iiiiaioe :

aeieoi? iaaee/ieo iaoe, i?ioani? AAAEI?IA E?Ae?ss ssE?AIA, Ee?anueea
iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i I. E.Uoieea IIC Oe?a?ie,
eaoaae?a n?iaeii? iaaeeoeeie, i?ioani? eaoaae?e.

aeieoi? iaaee/ieo iaoe, i?ioani? IAEAUOE AIAOIE?E IAO?IAE*,
Iaoe?iiaeuei?e iaaee/iee oi?aa?neoao ?i I.I. Aiaiiieueoey IIC Oe?a?ie,
eaoaae?a aini?oaeueii? oa?ai?? ? 2, i?ioani? eaoaae?e.

I?ia?aeia onoaiiaa: ?inoeooo oa?ai?? AII Oe?a?ie, a?aeae?eaiiy
aano?iaioa?ieia??, i. Oa?e?a.

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 17 ” /a?aiy 1999 ?. i 11-00
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.613.01 i?e
Ee?anuee?e iaaee/i?e aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I. E. Uoieea
IIC Oe?a?ie ca aae?anith: 254112, i. Ee?a, aoe. Aei?iaiaeeoeueea, 9,
aoae?oi??y ? 3.

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Ee?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I. E. Uoieea IIC Oe?a?ie ca
aae?anith: 254112, i. Ee?a, Aei?iaiaeeoeueea, 9.

Aaoi?aoa?ao ?ic?neaiee “ 15 ” o?aaiy 1999 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
I. ?. ?iiaiaiei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Ca aeaieie ??cieo aaoi??a (Aenaeue?iaeia
I.O.,1991; Iia??i A.A. oa ni?aaao.,1993; Aieioei I.O., Oaoei I.A.,1994;
Eaia?/oe E.A.,1994; No?ieeiI.I.,1996) ae?aceiaa oai?iaa
aeaaiaaeoeyoeiaei? eeoee(AOAeIE) noi?iaiaeaeo?oueny aeene?iac?yie
aeia/iiai i?oo?a(AEI) oa iicaia/?ieiaeo aeia/iaea?aeieo oeyo?a(IIAEAO) a
60-80% niinoa?aaeaiue. Iayai?noue noiooi?o aeene?iac?e IIAEAO o oai?eo
ia AO AeIE i?ecaiaeeoue aei ci?ie ee?i?/ii? ea?oeie caoai?thaaiiy,
oneeaaeith? ae?aaiinoeeo oa e?eoaaiiy iniiaiiai caoai?thaaiiy
(?aoao?eia TH. ?., No?ieei I. I.,1994; Eiia?ia O.?. oa ni?aaao., 1995;
Hoosshang M., Mollot M., Lorgan B., 1994).

I?iaeai? o?aaeaiiy i?aai?a aaiaoia?e?a?ii? ciie i?e AOAeIE
i?enay/ai? ?iaioe, a yeeo i?aee?aneth?oueny iioiaaiaoe/iee ca”ycie oa
ni?euei?noue aeaaiaaeoeyoeiaei? eeoee(AeIE) oa IIAEAO, aaoi?e
i?aee?aneththoue ni?euei?noue ?ia?aaoe?? neeciai? iaieiiee, i”ycaaeo oa
caeicenoeo no?oeoo? o ca”yceo c i?enooi?noth oae caaii?
“aioa?aeueii? ia?aiai? nenoaie“, ye iacaeaaeii? /anoeie aaaaoaoeaii?
ia?aiai? nenoaie, oa aiaeie?eiii? ?ioano?iaeueii? nenoaie (Ee?iia
I.E., 1974; Oaie?a I. I., 1978; ?aai/aieiaa ?.A., 1986). Ca?aeii
aeaiei e?oa?aoo?e (Aa?aoeia A.I.,1975; E?a?ae?aI. I.,1987;?aoao?eia
TH.?., I?eianueeee A.O., No?ieei I.I.,1995) neeciaa iaieiiea
aeaaiaaeoeyoeiaei? eeoee(NIAeIE) i?aaenoaaey? niaith ?aoeaioi?io ciio,
eio?a caaacia/o? ?aaoeyoe?th iioi?ii-aaaeoaoi?ii? ooieoe??
aeia/iaea?aeieo oeyo?a.

Iniiaiei ai?iiiaeueiei ?aaoeyoi?ii iioi?ii-aaaeoaoi?ii? ooieoe?? AEI ?
oieaoeenoie?i?i-iaie?aicei?i(OE-IC), eio?ee neioaco?oueny I-ee?oeiaie
NI AeIE. OE-IC aieeaa? ia nei?i/aiiy AEI oa ?icneaaeaiiy no?ieoa?a
Iaeae?, a oaeiae noeioeth? aecie?eiio ae?yeuei?noue i?aeoeoieiai?
caeice (Aaeea? E. ?., 1977; Mitsukawa T. et al., 1990; Ledeboer M. et
al., 1997). A oe?eiio ?yae? ?ia?o aea/aany ii?oieia?/iee noai NI AeIE
i?e AO AeIE (Aeaeoeae I.N., 1990; ?aoeiaa A. I. oa ni?aaao., 1990;
Iia??i A.A. oa ni?aaao., 1993; Eaia?/oe E.A.,1994). Aeeno?io?y oa
ao?io?y neeciai? iaieiiee(NI) aano?iaeoiaeaiaeueii? ciie
noi?iaiaeaeo?oueny cia/iei ciaioaiiyi e?eueeino? I-ee?oei oa
eiioeaio?aoe?? OE-IC o e?ia?, ui iiaea aooe ii/aoeiaei iaoai?ciii
?icaeoeo ii?ooaiue ne?i/oaaeueii? ooieoe?? AEI(Aaeea? E.?., A?yciiaa
I.A., ?eaaeea I.Ae.,1996).

Ca?aeii no/aniei iiaeyaeai iniiaiith i?e/eiith ii?oieia?/ieo ci?i NI
aano?iaeoiaeaiaeueii? ciie ? ?? ?io?eiaai?noue Helicobacter pylor?
(I?),

caaaeyee ?o aaeee?e i?ioaieaoe/i?e oa oeeoioiene/i?e aeoeaiino?, yea
i?ecaiaeeoue aei aeano?oeoeaii i?ie?oa?aoeaieo ci?i ee?oei (A?o?i E.
E, A?eai?”?a I.ss., ?naeia A.A., sseiaaiei A.I., 1993; Oa?/aieiI.A.,
Caai?oeei AE.A.,1998; Tytgat G.N.,1995). Aea ia oaia??oi?e /an
a?aenooi? aeine?aeaeaiiy aea a aea/aany aca?iica”ycie
iioi?ii-aaaeoaoi?ii? ooieoe?? AEI oa ii?oieia?/iiai noaio NI
aano?iaeoiaeaiaeueii? ciie ? ?? can?yiino? I?, noai ?-ee?oei NIAeIE oa
caeaaeiino? oe??? ooieoe?? a?ae ii?iae?caoe?? noaio NI
aano?iaeoiaeaiaeueii? ciie c aeeth/aiiyi aioeoaeaeiaaeoa?ii? oa?ai??.

Ca”ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Oaia
aeine?aeaeaiiy ? o?aaiaioii iaoeiai-aeine?aeii? ?iaioe iaaee/iiai
oaeoeueoaoo Noinueeiai aea?aeaaiiai oi?aa?neoaoo ? aea?ae?a?no?aoe??
0197U016606 “Noai aaaaoaoeaiiai caaacia/aiiy na?oeaai-noaeeiii? oa
o?aaii? nenoai o ae?oae oa aei?ineeo c aeieia?/ii iani?eyoeeai?
i?noeaaino?”.

Iaoa ? caaea/? aeine?aeaeaiiy. Iaoith aeaiiai aeine?aeaeaiiy aoea
?ic?iaea iaoiaaiaoe/ii iaa?oioiaaiiai iaoiaeo e?eoaaiiy noiooi?o
aeene?iac?e AEI a caeaaeiino? a?ae i?enooiino? Helicobacter pylori oa
ii?oieia?/iiai noaio NI aano?iaeoiaeaiaeueii? ciie. Aeey ?aae?caoe??
cacia/aii? iaoe iinoaaeai? ianooii? eiie?aoi? caaea/?:

1. Aea/eoe /anoioo oa oi?ie aeene?iac?e AEI o ianoaaeaieo oai?eo ia AO
AeIE

2. Aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao AO AeIE a ii?aeiaii? c
??cieie oeiaie aeene?iac?e AEI oa aca?iica”ycie oeio aeene?iac?e AEI c
o?eaae?noth caoai?thaaiiy ia AOAeIE oa a?e oai?eo.

3. I?iaanoe ii?oieia?/i? oa ii?oiiao?e/i? aeine?aeaeaiiy NI
aano?iaeoiaeaiaeueii? ciie i?e caaino?aii? AO AeIE oa i?ney e?eoaaiiy.

4. Aea/eoe ca aeiiiiiaith aeaeo?iiii? i?e?ineii?? noaio I-ee?oei NI
AeIE.

5. Aea/eoe /anoioo aeyaeaiiy oa nooi?iue can?yiino? NI
aano?iaeoiaeaiaeueii? ciie I? o ianoaaeaieo oai?eo.

6. Ni?anoaaeoe ii?oieia?/iee noai oa can?yi?noue NI
aano?iaeoiaeaiaeueii? ciie I? c /anoioith oa oa?aeoa?ii aeene?iac?e
AEI.

7. Aea/eoe aieea aioeoae?eiaaeoa?ii? oa?ai?? ia noai NI
aano?iaeoiaeaiaeueii? ciie ia /anoioo oa oei aeene?iac?? AEI.

8. ?ic?iaeoe iaoiaaiaoe/ii iaa?oioiaaiee iaoiae e?eoaaiiy aeene?iac?e
AEI o oai?eo ia AO AeIE.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. O ?acoeueoao? cae?eniaiiy
eiiieaeno ee?i?ei-?ino?oiaioaeueieo aeine?aeaeaiue aia?oa i?iaaaeaii
aeine?aeaeaiiy aieeao nooiaiy can?yiino? NI aano?iaeoiaeaiaeueii? ciie
I? ia oa?aeoa? aeene?iac?? AEI. Aeiaaaeaii, ui ii i??? c?inoaiiy
aaaeeino? AA e

aeoiaeai?oo oa nooiaiy can?yiino? NI aano?iaeoiaeaiaeueii? ciie
ca?eueoo?oueny e?euee?noue iaoe??io?a c noiooi?ie aeene?iac?yie AEI, a
oaeiae ci?ith?oueny ?o oa?aeoa?: ciaioo?oueny e?euee?noue niinoa?aaeaiue
a?ia?iioi?ii? aeene?iac?? oa ca?eueoo?oueny e?euee?noue oai?eo c
a?iiiioi?iith oi?iith aeene?iac?? AEI.

Aia?oa aea/aii noai I-ee?oei o oai?eo ia AO AeIE o ii?aeiaii? c
aeene?iac?yie AEI, oa anoaiiaeaii, ui i?e caaino?aii? AOAeIE a
?-ee?oeiao NIAeIE a?aeaoaathoueny ci?ie. ye? ia a?aeiiaeththoueny
iaa?oue i?ae /an ?ai?n?? AOAeIE.

?ic?iaeaii ?aoe?iiaeueiee, iaoiaaiaoe/ii iaa?oioiaaiee iaoiae
e?eoaaiiy aeene?iac?e AEI o oai?eo ia AO AeIE c o?aooaaiiyi nooeoo?e NI
aano?iaeoiaeaiaeueii? ciie oa i?enooiino? I? c i?ecia/aiiyi
aioeoae?eiaaeoa?ieo cania?a, ye? ciaioothoue aeoeai?noue AA e
aeoiaeai?oo oa iiceoeaii aieeaathoue ia oa?aeoa? ia?aa?ao noiooi?o
aeene?iac?e AEI.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. I?iaeaiiino?iaaia
caeaaei?noue aeene?iac?? AEI a?ae noaio NI aano?iaeoiaeaiaeueii? ciie
oa ?? can?yiino? I?.

Cai?iiiiiaaii iaoiaaiaoe/ii iaa?oioiaaiee iaoiae e?eoaaiiy aeene?iac?e
AEI c o?aooaaiiyi nooeoo?e NI aano?iaeoiaeaiaeueii? ciie oa ??
can?yiino? I?.

Oai?aoe/i? iieiaeaiiy aeena?oaoe?? aeeeaaeathoueny ia eaoaae?? oa?ai??
iaaee/iiai oaeoeueoaoo Noinueeiai aea?aeaaiiai oi?aa?neoaoo I?i?noa?noaa
ina?oe Oe?a?ie, Caii??cueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo IIC
Oe?a?ie, eaoaae?? oa?ai?? Caii??cueeiai ?inoeoooo oaeineiiaeaiiy
e?ea??a IIC Oe?a?ie, eaoaae?? oa?ai?? Oa?e?anueeiai ?inoeoooo
oaeineiiaeaiiy e?ea??a IIC Oe?a?ie, eaoaae?? oa?ai?? O?a?inueei?
iaaee/ii? noiiaoieia?/ii? aeaaeai?? IIC Oe?a?ie. Aeaeaii ?ioi?iaoe?eiee
eeno “Iaoiae aeei?enoaiiy aioeoae?eiaaeoa?ii? oa?ai?? i?e e?eoaaii?
noiooi?o aeene?iac?e aeia/iaea?aeieo oeyo?a o oai?eo c o?aaeaiiyie
neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie”. ?acoeueoaoe
aeine?aeaeaiiy ai?iaaaeaeaii a i?aeoeeo ioi?iie caei?ia”y: a
aano?iaioa?ieia?/iiio a?aeae?eaii? 5-? i?nueei? oa iaeanii? ee?i?/ii?
e?ea?i? i.Noie, a aano?iaioa?ia?/iiio a?aeae?eaii? iaeanii? ee?i?/ii?
oa 9-i? ee?i?/ii? e?ea?aiue i.Caii??aeaey. I?aeoe/ia aeei?enoaiiy
iaoa??ae?a aeena?oaoe?? i?aeoaa?aeaeo?oueny aeoaie ai?iaaaeaeaiiy c
a?aeiia?aeieo onoaiia.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii naiino?eii aecia/ai? caaaeaiiy
aeaiiai aeine?aeaeaiiy, i?iaiae?ciaaia iaoeiaa e?oa?aoo?a c i?iaeaie,
naiino?eii i?iaiaeeeinue ee?i?ei-aiaiianoe/ia ianoaaeaiiy oai?eo, aea??
oa i?ecia/aiiy e?eoaaiiy, eiio?ieue ca noaiii iaoe??io?a o i?ioean?
e?eoaaiiy, ?icoeo?iaea aeaieo oeueo?acaoeiaiai aeine?aeaeaiiy
nei?i/oaaeueii? ooieoe?? AEI, i?e?ioioia?aooaaiiy a?noieia?/ieo
c??c?a oa ?o ioe?iea, ii?oiiao?e/i? aeine?aeaeaiiy. Iniaenoi aaoi?ii
i?iaaaeaii

noaoenoe/iee aiae?c ?acoeueoao?a aeine?aeaeaiiy, iaienai? an?
?icae?ee aeena?oaoe??, noi?iiaai? aeniiaee oa cai?iiiiiaai? i?aeoe/i?
?aeiiaiaeaoe??. Ioi?ieaiiy aaoi?aoa?aoo cae?eniaii aaoi?ii naiino?eii.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aeiiia?aeaeenue: ia ?? Oe?a?inueeiio oeaei? aanoi?iaioa?ieia?a 23-25
aa?aniy 1997?. a i.Aei?i?iiao?ianuee; ia ?anioae?eainuee?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? “Aeinyaiaiiy oa iaae??oaii? ieoaiiy
aano?iaioa?ieia?? 7-8 ea?oiy 1998 ?. a i. Oa?e?a, a oaeiae ia ui??/ieo
iaoeiaeo nan?yo iaaee/iiai oaeoeueoaoo Noi AeO(1996-1998).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 6 ae?oeiaaieo

?ia?o, c ieo: 3 o i?io?eueieo iaaee/ieo aeo?iaeao, 3 o iaoa??aeao
c”?cae?a oa eiioa?aioe?e Oe?a?ie oa e?a?i NIAe.

Ianya oa no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 160
noi??ieao iaoeiiieniiai oaenoo oa neeaaea?oueny c? anooio, iaeyaeo
e?oa?aoo?e, 4 ?icae?e?a aeanieo aeine?aeaeaiue, aiae?co ?
ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiue, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e oa nieneo aeei?enoaieo aeaea?ae, yeee i?noeoue 275
aeaea?ae, c ieo 88 ca?oa?aeieo. ?iaioa ?ethno?iaaia 18 oaaeeoeyie, 26
?enoieaie, 5 a?ao?eaie.

CI?NO ?IAIOE

Eiioeiaaio ianoaaeaiiy oa iaoiaee aeine?aeaeaiiy. ?iaioa aeeiiaia ia
aac? aano?iaioa?ieia?/iiai a?aeae?eaiiy Noinueei? iaeanii? e?ea?i?.
Aoei ianoaaeaii 130 oai?eo ia AO AeIE(97 /ieia?e?a oa 33 ae?iie)
a?eii a?ae 17 aei 68 ?ie?a. O?eaae?noue caoai?thaaiiy noaiiaeea a?ae 0,5
aei 20 ?ie?a. Eiio?ieueio a?oio noaiiaeee 20 i?aeoe/ii caei?iaeo in?a
o a?oe? a?ae 17 aei 60 ?ie?a.

Aeey aea/aiiy aca?iica”yceo nei?i/oaaeueii? ooieoe?? AEI oa
ii?oieia?/ieo ci?i NI aano?iaeoiaeaiaeueii? ciie ie??i ee?i?/ieo
iaoiae?a ianoaaeaiiy oai?eo aoee canoiniaai? ne?aeoth/? iaoiaee
aeine?aeaeaiiy: o?a?iacioaaiaano?iaeoiaeaiineii?y(OAAAeN) c
i?eoe?eueiith a?iin??th NIAeIE oa oeoiea, a?noieia?/ia aeine?aeaeaiiy
a?iioao?a i?ney ?o oa?aoaaiiy aaiaoienee?i-aiceiii, ii?oiiao?e/ia
aeine?aeaeaiiy NI ueoiea; a?noieia?/ia aecia/aiiy Helicobacter
pylori(I?);oeueo?acaoeiaa aeine?aeaeaiiy nei?i/oaaeueii? ooieoe?? AEI;
aeaeo?iiii-i?e?ineii?/ia aeine?aeaeaiiy I-ee?oei NI AeIE.

Iayai?noue oa nooi?iue can?yiino? I? aio?aeueiiai a?aeae?eo oeoiea
aecia/aee ii?oieia?/iei iaoiaeii i?ney oa?aoaaiiy a?iioao?a ca
?iiaiianueeei — A?icith.

Oeueo?acaoeiaa aeine?aeaeaiiy AEI i?iaiaeeeinue ca iaoiaeeeaie,

iienaieie o no/ani?e e?oa?aoo??. Aecia/aee ia”?i AEI ye aei oae /a?ac 50
oaeeei i?ney aeia/ia?iiiai ni?aeaieo, yeee neeaaeaany c aeaio ne?eo
aeiaoe?a aai i?anoaeaia niaoaie. Ia”?i AEI aecia/aee ca oi?ioeith Iieye
A. C.(1968). Nei?i/oaaeueio ooieoe?th AEI ioe?ithaaee ii??aithth/e
ia”?ie AEI aei ? i?ney aeia/ia?iiiai ni?aeaieo, aecia/ath/e eiao?oe??io
nii?iaeiaiiy(Ein)(Iaeauoe A.I. oa ni?aaao.,1985). I?e ioe?ioe?
nei?i/oaaeueii? ooieoe?? AEI ie ei?enooaaeenue oei, ui o caei?iaeo in?a
i?ney aei/ia?iiiai ni?aeaieo AEI nei?i/o?oueny ia 1/3 — 2/3 a?ae
naiai ia?a?niiai ia”?io, i?e a?ia?e?iaoe/i?e aeene?iac?? nei?i/aiiy
AEI a?aeaoaa?oueny a?eueoa i?ae ia 66% , a i?e a?iie?iaoe/i?e
aeene?iac?? AEI nei?i/o?oueny iaio i?ae ia 33% a?ae naiai ia?a?niiai
ia”?io (Aioiiia I.N., ?ioaiia I.I.,1986).

I?iaaaeaii 16 aeaeo?iiii-i?e?ineii?/ieo aeine?aeaeaiue I-ee?oei NI
AeIE, c ieo: 4 o iaoe??io?a eiio?ieueii? a?oie, 6 — o oai?eo i?ae /an
caaino?aiiy, 6- i?ae /an ?ai?n?? AOAeIE. Oeueo?aoiie? c??ce, i?ney ?o
eiio?anooaaiiy oeeo?aoii naeioeth, aea/aeenue i?ae aeaeo?iiiei
i?e?ineiiii AIA-100A? i?e i?enei?thth/iio iai?oaeaii? 75 ea.
Ca?eueoaiiy i?aeae?aeinue aaeaeaaoia oe?eyi aeine?aeaeaiiy ?
eieeaaeinue o iaaeao 25000-50 000o.

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy. Na?aae ianoaaeaieo
oai?eo ia?aaaaeaee iniae /ieia?/i? noao? 97 in?a(74,6%), ae?iie aoei
33(25,4%). Na?aae /ieia?e?a iaea?eueoa e?euee?noue oai?eo
niinoa??aaeanue o a?eia?e a?oi? aei 20 ?ie?a, a na?aae ae?iie- o a?eia?e
a?oi? a?ae 30 aei 40 ?ie?a.

I?e ?iciiae?e? oai?eo iaio noaoae a caeaaeiino? a?ae o?eaaaeino?
caoai?thaaiiy ia AOAeIE aoei aeyaeaii, ui na?aae ae?iie iaea?eueoa
e?euee?noue oai?eo niinoa??aaeanue c ae?aceiaei aiaiiacii aei 1
?ieo(36,4%), a na?aae /ieia?e?a iaea?eueoa e?euee?noue iaoe??io?a
a?aecia/aeanue c o?eaae?noth caoai?thaaiiy a?ae 1 aei 5 ?ie?a(38,1%).
Oaeei /eiii, AOAeIE o /ieia?e?a ii/eia?oueny o a?eueo iieiaeiio a?oe? ?
ia iiiaio ianoaaeaiiy a iaeiaeiaeo a?eiaeo a?oiao /ieia?ee iathoue
a?eueo iiaeiaaeaiee ae?aceiaee aiaiiac, ui na?ae/eoue i?i a?eueo
aa?aneaiee ia?aa?a caoai?thaaiiy o ieo, a ii??aiyii? c ae?ieaie.

A caeaaeiino? a?ae oeio aeene?iac?? AEI oai?? aoee ?iciiae?eai? ia 3
a?oie: 1 a?oia-31 oai?ee c ii?iaeueiith nei?i/oaaeueiith ooieoe??th AEI;
2 a?.-56 oai?eo c a?iae?iaoe/iith aeene?iac??th AEI, 3 a?.-43 oai?eo c
a?iie?iaoe/iith aeene?iac??th AEI, o./. o 76,2% oai?eo ia AOAeIE
a?aecia/aeenue ii?ooaiiy nei?i/oaaeueii? ooieoe?? AEI. A?ia?e?iaoe/ia
oi?ia aeene?iac?? aeyaeaia o 43,1% ianoaaeaieo. Aiia noaiiaeea na?aae
/ieia?e?a — 39,1% oa 54,5% niinoa?aaeaiue na?aae ae?iie.A?iie?iaoe/ia
aeene?iac?y AEI aecia/aia o 33,1% ianoaaeaieo, a oiio /ene? na?aae

/ieia?e?a- 34,0 %, a ae?iee neeaaeaee 30,3 % niinoa?aaeaiue. Iaea?aeai?
aeai? ocaiaeaeothoueny c e?oa?aoo?ieie a?aeiiinoyie, ca?aeii yeeo
AOAeIE o 80-100% oai?eo noi?iaiaeaeo?oueny ii?ooaiiyie nei?i/oaaeueii?
ooieoe?? AEI(?aoao?eia TH. ?., No?ieei I. I.,1994; Eaia?/oe E. A.,
1994).

Aiae?coth/e iniiai? nea?ae oai?eo ia AO AeIE a ii?aeiaii? c
aeene?iac?yie AEI anoaiiaeaii, ui i?e a?iie?iaoe/i?e aeene?iac?? AEI,
ye i?aaeei, niinoa??aaany ieth/ee, iii??ii? ?ioaineaiino? a?eue o
i?aaiio i?ae?aaa?”?. I?e a?ia?e?iaoe/i?e oi?i? aeene?iac?? AEI oai??
nea?aeeeenue ia ia?aeiiiiae?aiee ?ioaineaiee a?eue o i?aaiio
i?ae?aaa?”?. Iacaeaaeii a?ae oeio aeene?iac?? AEI a?eue o i?aaiio
i?ae?aaa?”? aoa iia”ycaiee c i?eeiiii aino?i? ?ae?, /anoi ii?aeioaaany
c ii?ooaiiyie ?aaeeio oa?/oaaiiy, c ineoiaiioe?iiaeueieie no?anaie,
aaeeaaiiyi aeeiaieth. ??aae?aoe?y aieth aoea oeiiaith: /ano?oa a i?aaa
iea/a, ??aeoa a i?aao eiiaoeo, ae?eyieo na?oey.

Aiae?c aca?iica”yceo oeio aeene?iac?? AEI oa o?eaaeino? caoai?thaaiiy
ia AOAeIE iieacaa, ui o in?a c ae?aceiaei aiaiiacii aei 1 ?ieo, ia
caeaaeii a?ae noao? oai?eo, ia?aaaaeaea a?ia?e?iaoe/ia aeene?iac?y
AEI(48,6%). Na?aae oai?eo c o?eaae?noth caoai?thaaiiy ia AOAeIE
a?ae 1 aei 5 ?ie?a oaeiae ia?aaaaeaea a?ia?e?iaoe/ia oi?ia
aeene?iac?? AEI(44,8%), a oie aea /an ??cei ca?eueooaaeanue e?euee?noue
aeiaaee?a a?iie?iaoe/ii? oi?ie aeene?iac?e AEI (31,1%), ui
a?aeaoaaeinue ca ?aooiie

ciaioaiiy e?eueeino? oai?eo aac ii?ooaiue iioi?ii-aaaeoaoi?ii?
ooieoe?? AEI. I?e o?eaaeino? ae?aceiaiai aiaiiaco a?ae 5 aei 10 ?ie?a
a?iie?iaoe/ia oi?ia aeene?iac?? AEI aaea ?a?no?oaaeanue o 50,0%
aeiaaee?a. Caa?oa? ia naaa oaaao, ui na?aae oai?eo c o?eaae?noth
caoai?thaaiiy ia AO AeIE a?eueoa 10 ?ie?a cia/ii c?inea e?euee?noue
aeiaaee?a a?iie?iaoe/ii? aeene?iac?? AEI (52,9%) ? caeeoeeenue
eeoa iiiaeeiie? aeiaaeee ii?iie?iac?? AEI. Oaeei /eiii, /ei a?eueoa
o?eaae?noue caoai?thaaiiy ia AO AeIE, oei a?eueoa e?euee?noue oai?eo
c noiooi?ie aeene?iac?yie AEI, a oaeiae ci?ith?oueny ?o oa?aeoa?:
ia?aaaaeath/a ia ii/aoeo caoai?thaaiiy a?ia?e?iaoe/ia oi?ia ci?ith?oueny
a?iie?iaoe/iith, ui ei?aeth? c aeaieie Aenaeue?iaeiaa I.O.( 1991) oa
No?ieei I. I. (1996).

Aiae?c aca?iica”yceo oeio aeene?iac?? AEI oa a?eo oai?eo ia AOAeIE
iieacaa: na?aae oai?eo aei 50 ?ie?a ia?aaaaeaea a?ia?e?iaoe/ia
aeene?iac?y AEI. I?ney 50 e?oiueiai a?eo, ye na?aae /ieia?e?a oae ?
na?aae ae?iie, ii/eia? ia?aaaaeaoe a?iie?iaoe/ia oi?ia aeene?iac??
AEI(70,0%). Iniaeeai oea aeaeii ia oai?eo a?eiai? a?oie aieueoa 60
?ie?a-85,7% niinoa?aaeaiue. I?eaa?oa? oaaao, ui na?aae ae?iie c AO
AeIE aei 30 e?oiueiai a?eo, ia a?aei?io a?ae /ieia?e?a, ie ia ciaeoee
aeiaeiiai aeiaaeeo a?iie?iaoe/ii? oi?ie aeene?iac?? AEI.

Iaie anoaiiaeaii, ui o oai?eo ae?iie a?eii noa?oa 40 ?ie?a ia aoei
aeiaaee?a caa?aaeaiiy ii?iaeueii? nei?i/oaaeueii? ooieoe?? AEI, oiaoi
an? aiie iaee oo /e ?ioo oi?io aeene?iac?? AEI. Na?aae inoaii?o
nii/aoeo, aei 50 e?oiueiai a?eo, ia?aaaaea? a?ia?e?iaoe/ia oi?ia
aeene?iac?? AEI, a i?ney 50 ?ie?a — a?iie?iaoe/ia. Oea na?ae/eoue i?i
o?niee ca”ycie o?aaeaiiy NI aano?iaeoiaeaiaeueii? ciie oa
nei?i/oaaeueii? ooieoe?? AEI o oai?eo ia AOAeIE, aea na?aae ae?iie
i?ioean ci?ie oeio aeene?iac?? a?ae a?ia?- aei a?iie?iaoe/ii? oi?ie
aeene?iac?? AEI eaea iia?euei?oa, a ii??aiyii? c /ieia?eaie.

Aeey ioe?iee nei?i/oaaeueii? ooieoe?? AEI ie aeine?aeaeoaaee ci?ie
e?i?eieo ?ici???a AEI ye aei oae ? i?ney aeia/ia?iiiai ni?aeaieo.
Iioeiaeueiei aeey aea/aiiy nei?i/oaaeueii? ooieoe?? AEI ? ioe?iea
ia”?io AEI, a iaea?eueoo ?ioi?iaoe?th i?i nei?i/oaaeueio ooieoe?th AEI
aea? Ein AEI, yeee aeaco? ia i?ioeaioi? ci?ie ia”?io AEI i?ney i?iae,
oa aea? iiaeeea?noue ii??aithaaoe iieacieee a caeaaeiino? a?ae oeio
aeene?iac?? AEI, ia caaaeath/e ia ??ci? io?eiai? iniaia? aa??aoe??
e?i?eieo ?ici???a AEI.

Iaie anoaiiaeaii, ui i?e ii?iie?iac?? AEI Ein AEI noaiiaea 43,6+2,1%,
i?e a?ia?e?iaoe/i?e aeene?iac?? AEI Ein aoa o na?aaeiueiio 71,3+1,4%,
i?e a?iie?iaoe/i?e aeene?iac?? AEI Ein AEI aeyaeany 22,8+1,2%. I?e
ii??aiyii? ia”?io AEI caeaaeii a?ae noao? oai?eo i?e ??cieo oeiao
aeene?iac?? AEI noaoenoe/ii aeinoia??ii anoaiiaeaii ca?eueoaiiy eiai
ia”?io na?aae ae?iie ye aei oae ? i?ney aeia/ia?iiiai ni?aeaieo i?e
a?iie?iaoe/i?e aeene?iac?? AEI( ?<0,01). I?e aiaeineii?/iiio aeine?aeaeaii? anoaiiaeaii, ui iaoieia?/i? ci?ie a?aeaoaathoueny cia/ii /ano?oa c aieo aio?aeueiiai a?aeae?eo oeoiea oa eoeiaeoe? AeIE, i?ae c aieo ooiaeaeueiiai a?aeae?eo oeoiea. Iaea?aeai? iaie aeai? ocaiaeaeothoueny c aeniiaeaie ?ioeo aeine?aeiee?a(A?o?i E.E. oa ni?aaao., 1993). Aio?aeueiee aano?eo oa aeoiaeai?o aeyaeaii o an?o ianoaaeaieo. A?iceai? o?aaeaiiy NI eoeiaeoe? AeIE oa ?? aeaoi?iaoe?y a?aecia/aeanue /ano?oa na?aae /ieia?e?a. Iiiaeeiie? ae?acee eoeiaeoe? AeIE o /ieia?e?a niinoa??aaeenue ia?aaaaeii ia caaei?e no?ioe? eoeiaeoe? AeIE oa iaee ?ici??e a?eueoa 5 ii, a na?aae ae?iie niinoa??aaeanue ia?aaaaeia eieae?caoe?y iiiaeeiieeo ae?acie ia ia?aaei?e no?ioe? eoeiaeoe? AeIE c ?ici??aie iaioa 5 ii. *enaeuei? ae?acee eoeiaeoe? AeIE oaeiae niinoa??aaeenue /ano?oa na?aae /ieia?e?a i?ae na?aae ae?iie. Aano?eo oa aeoiaeai?o ? ia no?eueee ee?i?/i? iiiyooy, ne?eueee a?noieia?/i?, oiio a iiaeaeueoiio aeey i?aeoaa?aeaeaiiy ae?aaiico ie canoiniaoaaee a?noieia?/i? e?eoa???. I?e a?noieia?/iiio aeine?aeaeaii? AA aoa i?aeoaa?aeaeaiee o an?o oai?eo ia AOAeIE. Oae, a oe?eiio aac a?aooaaiiy noao? oai?eo AA Ino. aeyaeaii o 35,4% ianoaaeaieo, AA II no. a?aecia/aany a 46,1% niinoa?aaeaiue, AA IIIno. aeyaeaii o 18,5% oai?eo ia AO AeIE. I?e ?iciiae?e? oai?eo ca noaooth ie ia ciaeoee noaoenoe/ii aeinoia??ii? ??cieoe? a i?iyaao aaaeeino? AA. Aeoiaeai?o c ??ciei nooiaiai aaaeeino? aoei i?aeoaa?aeaeaii a?noieia?/ii oaeiae o an?o oai?eo. Iii??ii ae?aaeaiee aeoiaeai?o aoei aeyaeaii o 31,5% ianoaaeaieo, ae?aaeaiee aeoiaeai?o o 52,3%, aeoiaeai?o c ao?io??th o 16,2% oai?eo ia AOAeIE. I?e ?iciiae?e? oai?eo ca noaooth anoaiiaeaii, ui iii??ii ae?aaeaiee aeoiaeai?o aeyaeyany o 45,5% ae?iie, a na?aae /ieia?e?a eeoa a 26,8% niinoa?aaeaiue. Ae?aaeaiee aeoiaeai?o a?noieia?/ii i?aeoaa?aeaeaii o 45,5% ae?iie, a o /ieia?e?a a 54,6% niinoa?aaeaiue. Aeoiaeai?o c ao?io??th anoaiiaeaii o 9,0% ae?iie ? o 18,6% oai?eo /ieia?e?a. Oaeei /eiii, na?aae ae?iie, a ii??aiiyi? c /ieia?eaie, ia?aaaaeaea iiaa?oiaaa oi?ia aeoiaeai?oa ? cia/ii ??aeoa cono??/aeanue eiai ao?io?/ia oi?ia. Ie aea/eee /anoioo oa nooi?iue can?yiino? NI aano?iaeoiaeaiaeueii? ciie I? o iaoeo oai?eo. Aoei anoaiiaeii, ui o 84,6% ianoaaeaieo oai?eo AO AeIE a ii?aeiaii? c aeene?iac?yie AEI a?aecia/aeanue ?io?eiaai?noue HP. ?io?eiaai?noue I? ? no., aac aeeoa?aioe?aoe?? oai?eo ca noaooth, a?aecia/aeanue o 37(33,6%) oai?eo, can?yi?noue I? ?? no.- o 53(48,2%) ianoaaeaieo, a ?io?eiaai?noue I? ???no. aoea aecia/aia o 20 (18,2%) iaoe??io?a. I?e ni?anoaaeaii? nooiaiy can?yiino? I? oa aaaeeino? ii?oieia?/ieo ci?i c aieo NI aano?iaeoiaeaiaeueii? ciie, aoa i?aeoaa?aeaeaiee aca?iica”ycie nooiaiy aaaeeino? AA e aeoiaeai?oo oa nooiaiy can?yiino? NI HP. Oae, i?e AA I no. can?yi?noue I? Ino. niinoa??aaeanue o 82,2% oai?eo, II no. o 17,8% ianoaaeaieo. Na?aae iaoe??io?a c AA II no. can?yi?noue I? Ino. aoea aeyaeaia a 8,9% aeiaaee?a, IIno. o 77,8% ianoaaeaieo, III no. - o 13,3% oai?eo. I?e AA IIIno. ?io?eiaai?noue I? Ino. aeyaeaia ia aoea, I1 no. - o 34,5% oai?eo,oa can?yi?noue I? III no.-o 65,5% ianoaaeaieo. Iaea?aeai? iaie ?acoeueoaoe ni?aiaaeathoue c aeniiaeaie ?ioeo aaoi??a ui aei iaoiaaiaioe/ii? ?ie? I? a ?icaeoeo o?aaeaiue NI aano?iaeoiaeaiaeueii? ciie i?e AOAeIE (Oa?/aiei I. A., Caai?oeei AE.A.,1998; Tytgat G.N., 1995) oa? i?aeoaa?aeaeo? oaeo aca?iica”yceo a?noieia?/ieo ci?i NI aio?aeueiiai a?aeae?eo oeoiea oa aeoeaiino? AA c? nooiaiai can?yiino? HP. Oaeei /eiii, i?e AOAeIE iaoieia?/i? ci?ie, i?aeoaaaeaeai? a?noieia?/ii, a?aeaoaathoueny cia/ii /ano?oa c aieo NI aio?aeueiiai a?aeae?eo oeoiea oa eoeiaeoe? AeIE, i?ae c aieo NI ooiaeaeueiiai a?aeae?eo oeoiea. Iath/e ia oaac?, ui iaoith aeaii? ?iaioe aoei anoaiiaeaiiy caeaaeiino? nei?i/oaaeueii? ooieoe?? AEI a?ae ii?ioieia?/ieo ci?i NI aano?iaeoiaeaiaeueii? ciie, ie ia iiaee caeeoeoe aac oaaae iioieia?/iee noai I-ee?oei NIAeIE. Aeaeo?iiii-i?e?ineii?/ia aeine?aeaeaiiy I-ee?oei a oiiaao caaino?aiiy AOAeIE aeyaeei iayai?noue aiaieu aioo??oiueiee?oeiieo iae?ic?a oeeoiieaciaoe/ieo no?oeoo?. E?cen ciai?oi?o iaia?ai oa e?eno i?oioiiae??e na?ae/aoue i?i aeeaie? ii?ooaiiy ieenethaaeueii-a?aeiiaeo i?ioean?a a aiaeie?eiioeeoao AeIE. Na?ae/aiiyi oeeo ii?ooaiue ? ??cea cieaeaiiy nae?aoi?ii? aeoeaiino? oeeo ee?oei. Ui i?aeoaa?aeaeo?oueny aeyaeaiiyi ae?eyiie o?aaiaioaoe?? iaia?ai a?aioey?iiai aiaeiieaciaoe/iiai ?ao?e?eoia c ciaioaiiyi e?eueeino? ?eainii ia iiaa?oi? eiai iaia?ai, a oaeiae caaaeueia cieaeaiiy e?eueeino? ?eainii, ii?ooaiiy no?oeoo?e ieanoei/aoiai oeeoiieaciaoe/iiai eiiieaena Aieueaeae? oa cia/ia ciaioaiiy e?eueeino? nae?aoi?ieo a?aioe. Ana oea ?acii iiaea aanoe aei cieaeaiiy i?iaeoeoe?? ? OE-IC a i?aai?ci? ? aiane?aeie oeueiai-aei ii?ooaiue nei?i/oaaeueii? ooieoe?? AEI. I?ney e?eoaaiiy, a noaae?? ?ai?n??, oeueo?ano?oeoo?i? ci?ie i?aaiae I-ee?oei ia iineee aeano?oeoeaiiai iai?yieo.Iaeiae ??aaiue nae?aoi?ii? iiaeeeaino? ee?oei a oiiaao ?ai?n?? AOAeIE, noaey/e ii noaio oeueo?ano?oeoo?, caeeoaany iecueeei. Ci?ie no?oeoo?e i?oioiiae??e, c ciaioaiiyi e?eueeino? e?eno oa ?iciooaiiyi ciai?oiuei? iaia?aie na?ae/aoue i?i ii?ooaiiy a?iaia?aaoe/ieo i?ioean?a, ye? i?io?eathoue ia noai?e?ineii?/iiio ??ai?. Aeao?oeeo a?iaia?aaoe/iiai caaacia/aiiy neioaoe/ieo ?aaeoe?e aaaea aei iaiiaeeeaino? cae?eniaiiy aiaeie?eiioeeoaie aaeaeaaoieo aioo??oiueiee?oeiieo ?aia?aoeaieo i?ioean?a. Oea i?aeoaa?aeaeo?oueny aaeoie?caoe??th a?aioey?ii? aiaeiieaciaoe/ii? n?oee, eio?a ii?aeio?oueny c /anoeiaith aeano?oeoe??th eiai iaia?ai, ui na?aeioeoao? i?i nae?aoi?io iaiiaiioe?ii?noue ee?oei neioacoth/eo OE-IC. Oaeei /eiii, o oai?eo ia AOAeIE a noaae?? ?ai?n?? a ee?oeiao, neioacoth/eo OE-IC, i?ioeane ciaoiaeyoueny a aeeiai?/i?e ??aiiaac?, oiaoi iaeii/anii a?aeaoaathoueny ye aeeno?io?/i?, oae ? eiiiainaoi?ii-?aia?aoeai? i?ioeane. Noai oeueo?ano?oeoo?e ee?oei, neioacoth/eo OE-IC, aeicaiey? i?eionoeoe, ui i?e AO AeIE a noaae?? ?ai?n?? e?euee?noue aeae?ey?iiai OE-IC nooo?ai cieaeo?oueny. A e?oa?aoo?? ie ia ciaeoee aeineae?aeaiue ii aea/aiith noai?e?ineii?/ii? i?aai?caoe?? ?-ee?oei NIAeIE o oai?eo ia AOAeIE c noiooi?ie aeene?iac?yie AEI aea Aaeea? E.?. oa ni?aaao.(1996) a nai?o aeine?aeaeaiiyo aeacothoue ia cieaeaiiy eiioeaio?aoe?? o e?ia? OE-IC o oai?eo c ao?io?/iei aeoiaeai?oii, aecia/aii? ?aae?i?ioiieia?/iei iaoiaeii. I?e aiae?c? aca?iica”yceo nei?i/oaaeueii? ooieoe?? AEI oa ii?oieia?/ieo ci?i NI aio?aeueiiai a?aeae?eo oeoiea aeyaeaii, ui o oai?eo c AA?no. a 47,8% aeiaaee?a a?aecia/aeanue a?ia?e?iaoe/ia aeene?iac?y AEI, o 52,2% ianoaaeaieo nei?i/oaaeueia ooieoe?y AEI aoea ia ii?ooaia. Na?aae 60 oai?eo c AA??no. o 56,7% aeiaaee?a niinoa??aaeanue a?ia?iioi?ia aeene?iac?y AEI, a o 31,7% oai?eo a?aecia/aeanue a?iiiioi?ia aeene?iac?y. Eeoa o 11,7% iaoe??io?a oe??? a?oie niinoa??aaeanue ii?iie?iac?y AEI. Na?aae an?o 24 oai?eo c AA ???no. aeyaeaia a?iiiioi?ia aeene?iac?y AEI. I?e iii??ii ae?aaeaiiio aeoiaeai?o? o 56,1% oai?eo ia AO AeIE a?aecia/aeanue a?ia?e?iaoe/ia aeene?iac?y AEI, a o 43,9% aeiaaee?a nei?i/oaaeueia ooieoe?y AEI aoea ia ii?ooaia. Na?aae oai?eo c ae?aaeaiei aeoiaeai?oii a?ia?e?iaoe/ia aeene?iac?y AEI niinoa??aaeanue o 48,5% ianoaaeaieo, a?iie?iac?y AEI aeyaeaia o 32,4% oai?eo, ii?iie?iac?y AEI a?aecia/aeanue o 19,1% niinoa?aaeaiue. O an?o oai?eo c ao?io?/iei aeoiaeai?oii(21 oai?ee) aeyaeaia a?iiiioi?ia aeene?iac?y AEI. Aiae?coth/e aca?iica”ycie oeio aeene?iac?? AEI oa nooiaiy can?yiino? NI aio?aeueiiai a?aeae?ea oeoiea I? anoaiiaeaii, ui na?aae oai?eo c can?yi?noth I?? no. (37 iaoe??io?a) ii?iie?iac?y AEI a?aecia/aeanue o 64,8%, a?ia?e?iaoe/ia aeene?iac?y AEI aoea aeyaeaia o 35,2% oai?eo. Na?aae 53 ianoaaeaieo c ?io?eiaai?noth I? ??no. ii?iie?iac?y AEI a?aecia/aeanue o 9,4% in?a, a?ia?e?iaoe/ia oi?ia aeene?iac?? aoea aeyaeaia o 56,6% oai?eo, a a?iie?iaoe/ia aeene?iac?y AEI niinoa??aaeanue o 34,0% iaoe??io?a. O an?o 24 oai?eo ia AO AeIE c can?yi?noth I? ???no. a?aecia/aeanue a?iie?iaoe/ia oi?ia aeene?iac?? AEI. Oaeei /eiii, i?e aiae?c? acaa?iica”yceo nei?i/oaaeueii? ooieoe?? AEI oa ii?oieia?/ieo ci?i NI aano?iaeoiaeaiaeueii? ciie oa can?yiino? ?? I? anoaiiaeaii, ui ii i??? ia?inoaiiy nooiaiy AA oa aeoiaeai?oo oa ?io?eiaaiino? I?, oiaoi, nooiaiy aaaeeino? ii?oieia?/ieo ci?i c aeeno?io?/ieie oa ao?io?/ieie o?aaeaiiyie o iie?iaiiio ai?oae?th, ee?oeiao caeic oa aiaeie?eiieo ee?oeiao, niinoa??aa?oueny ca?eueoaiiy e?eueeino? oai?eo c aeene?iac?yie AEI a oe?eiio. E??i oiai, c oaeith ae iine?aeiai?noth niinoa??aa?oueny ci?ia oa?aeoa?o aeene?iac??: iinooiiaa ca?eueoaiiy e?eueeino? a?iie?iaoe/ii? ?? oi?ie ia oii? ciaioaiiy a?ia?e?iaoe/ii? oi?ie aeene?iac?? AEI. I?e AA ??? no. oa ao?io?/iiio aeoiaeai?oo e ?io?eiaaiino? I? ???no., aea ia?aaaaeathoue ao?io?/i? ci?ie a NI aano?iaeoiaeaiaeueii? ciie, a?aecia/aeanue eeoa a?iiiioi?ia aeene?iac?y AEI. Iaea?aeai? iaie aeai? i?i aca?iica”ycie nei?i/oaaeueii? ooieoe?? AEI oa ii?oieia?/iiai noaio NI aano?iaeoiaeaiaeueii? ciie o oai?eo ia AOAeIE ei?aeththoue c aeaieie e?oa?aoo?e, aea i?aee?aneth?oueny, ui aeae aeene?iaoe/ieo iie?ooaiue iia”ycaiee c oa?aeoa?ii caiaeueiiai i?ioeano a NI aano?iaeoiaeaiaeueii? ciie, nooi?iue aaaeeino? yeiai caeaaeeoue a?ae noaae?? AOAeIE(Ooeaee?ia ?. I., O?e?iiiia ?.I., 1986; ?aoeiaa A.I. oa ni?aaao., 1990; Iia??i A. A. oa ni?aaao., 1993).Oea aeicaiey? iaiieyaaoe ia aeoioe?, ui naia aeano?oeoeaieie ci?iaie NIAeIE, a oaeiae ciaioaiiyi /enea ee?oei, i?iaeooethth/eo OE-IC, ?iciianthaeaeaiinoth ? nooiaiai i?iyao oeueiai i?ioeano, aeenaaeainii o?aaieo ai?iii?a iiaeia iiynieoe a?iie?iac?th AEI. Ca iaoith aeoieith, aeieacii aca?iica”yceo oa?aeoa?o aeene?iac?? AEI oa ii?oieia?/iiai noaio NI aano?iaeoiaeaiaeueii? ciie oa ?? can?yiino? I? ? ?acoeueoaoe i?iaaaeaiiai e?eoaaiiy oai?eo. Aoei i?ie?eiaaii 63 oai?eo ia AO AeIE oa noiooi? aeene?iac?? AEI. Ianoaaeai? oai??, a caeaaeiino? a?ae neeaaeo i?iaaaeaiiai e?eoaaiiy, aoee ?iciiae?eai? ia 2 a?oie. Ia?oo a?oio(35 oai?eo) neeaaeaee iaoe??ioe, ye? iaea?aeoaaee eiiieaenia e?eoaaiiy c aeeth/aiiyi aioeoae?eiaaeoa?ieo i?aia?ao?a a ??cieo aa??aioao (aeieaoi?e I-2 a?noai?iiaeo ?aoeaioi??a, ?iaea?oi?e I+ E+ AOO-ace, aioea?ioeee). Ae?oao a?oio(28 in?a) neeaaeaee oai??, ye? e?eoaaeenue aiaoeaoi?ii oa iaea?aeoaaee aacenio i?ioeae?aceiao oa?ai?th aac cania?a, ni?yiiaaieo ia a?aaeeeaoe?th I?. Iaoe??ioai ae?oai? a?oie i?ecia/aee aeieaoi?e I-2 a?noai?iiaeo ?aoeaioi??a, ?iaea?oi?e I+ E+ AOO-ace, aioaoeeaei? i?aia?aoe. Iaeii/anii c oeei e?eoaaiiyi oai?ei iaio a?oi, a caeaaeiino? a?ae oeio aeene?iac?? AEI, i?iaiaeeeanue ?oiy iaaeeeaiaioicia ei?aeoe?y. I?ney i?iaaaeaiiai e?eoaaiiy oai?eo iaio a?oi i?e eiio?ie? I? can?yiino? anoaiiaeaii, ui na?aae 35 oai?eo, ye? iaea?aeoaaee aioeoae?eiaaeoa?io oa?ai?th, a?aaeeeaoe?? I? ia aaeaeinue aeinyaoe eeoa o 25,7% iaoe??io?a oe??? a?oie, a na?aae 28 oai?eo ae?oai? a?oie can?yi?noue I? caeeoeeanue o 71,4% ianoaaeaieo. I?e oeueiio o?aaa i?aee?aneeoe, ui a?aaeeeaoe?y I? ia aoea aeinyaiooa o iaoe??io?a ia?oi? a?oie c iiia?aaeiueith ?io?eiaai?noth I? ??? no. oa AA ???no. An? aeiaaeee oni?oiiai e?eoaaiiy oae?eiaaeoa??ico i?eoiaeyoueny ia iiia?aaeith can?yi?noue I? ? oa ?? no. Oaeei /eiii, aecia/ath/e nooi?iue ?io?eiaaiino? I? oa ii?oieia?/iee noai NI, iiaeia i?iaiicoaaoe aoaeo e?eoaaiiy oae?eiaaeoa??ico oa a aeiaaeeao can?yiino? I? ???no. aeei?enoiaoaaoe a?eueo ?ioaineaio oa o?eaaeo oa?ai?th ? i?e iaoeo aeine?aeaeaiiyo an? oai??, o yeeo i?e eiio?ie? can?yiino? I? caeeoaeanue ?io?eiaai?noue I?, i?iaeiaaeoaaee e?eoaaiiy ye oeueiai aeiaaathoue no/ani? ?aeiiaiaeaoe??. I?e ii?oieia?/iiio aeine?aeaeaii? NI aano?iaeoiaeaiaeueii? ciie o oai?eo ia?oi? a?oie i?ney aioeoae?eiaaeoa?ii? oa?ai?? anoaiiaeaii: o 12 oai?eo c AA ? no. oa ??cieie nooiaiyie ?io?eiaaiino? I? ii?iae?caoe?y ii?oieia?/iiai noaio NI aio?aeueiiai a?aeae?eo oeoiea niinoa??aaeanue o 6 iaoe??io?a oa a?aecia/aeanue 100% a?aaeeeaoe?y I?. Na?aae 16 oai?eo c AA ??no. oa ?io?eiaai?noth I? i?ney e?eoaaiiy noai NI aio?aeueiiai a?aeae?eo aeecueeee aei ii?ie a?aecia/aany o 5 iaoe??io?a, AA ? no. aeyaeaii o 6 ianoaaeaieo, AA ?? no.-o 5 iaoe??io?a oa niinoa??aaeenue eeoa iiiaeeiie? aeiaaee? can?yiino? I? ? oa ?? no. O an?o 7 oai?eo c AA ???no. oa ?io?eiaai?noth I? ???no. ii?iae?caoe?? ii?oieia?/iiai noaio NI oa a?aaeeeaoe?? I?, i?ney i?iaaaeaiiai e?eoaaiiy, aeinyaoe ia aaeaeinue. Oaeei /eiii, i?ney aioeoae?eiaaeoa?iiai e?eoaaiiy, o an?o oai?eo iie?aueany ii?oieia?/iee noai NI aano?iaeoiaeaiaeueii? ciie, a i?e AA ? no. a?aeaoaaeanue iaa?oue ii?iae?caoe?y a?noieia?/iiai noaio NI. O?eueee a aeiaaeeao AA ???no., ia aeeaey/enue ia io?eiaiiy ee?i?/iiai aoaeoo, iiceoeai? ci?ie a ii?oieia?/iiio noai? NI aano?iaeoiaeaiaeueii? ciie aoee iacia/i?. I?e ii?oieia?/iiio aeine?aeaeaii? NI aano?iaeoiaeaiaeueii? ciie o oai?eo, i?ie?eiaaieo aac canoinoaaiiy aioeoae?eiaaeoa?ieo cania?a, anoaiiaeaii, ui na?aae 10 oai?eo c ii?iaeueiei noaiii aio?aeueiiai a?aeae?eo oeoiea o 2 c ieo a?aecia/aeanue ?io?eiaai?noue I? ? no. O an?o 7 iaoe??io?a c AA ? no. niinoa??aaeanue can?yi?noue I?. Na?aae an?o 8 oai?eo c AA ??no. oaeiae aoea aeyaeaia ?io?eiaai?noue I? ??ciiai nooiaiy aaaeeino?. O 3 oai?eo ao?io?/iei AA a?aecia/aeanue ?io?eiaai?noue I? ?? oa ???no., oiaoi, o 71,4% ianoaaeaieo aoea anoaiiaeaia can?yi?noue I?. I?ney aioeoae?eiaaeoa?iiai e?eoaaiiy nei?i/oaaeueia ooieoe?y AEI i?eeoea aei ii?ie o 12 c 26 iaoe??io?a, aeene?iac?? AEI caeeoeeenue o 40,0% ianoaaeaieo, a na?aae oai?eo ae?oai? a?oie aeene?iac?? AEI niinoa??aaeenue i?ney e?eoaaiiy o 18 iaoe??io?a(64,3% niinoa?aaeaiue). Iaa?oue i?e canoino- aaii? aioeoae?eiaeoa?ii? oa?ai?? iie?auaiiy nei?i/oaaeueii? ooieoe?? AEI ia aaeaeinue aeinyaoe na?aae iaoe??io?a c iiia?aaeiueith can?yi?noth I? ???no. oa AA ???no. e ao?io?/iiio aeoiaeai?o?. Oe??? iaoe aaeaeinue aeinyaoe o?eueee a aeiaaeeao AA ? oa ??no., iii??iiio oa ae?aaeaiiio aeoiaeai?o? oa can?yiino? I? ?oa ?? nooiaiy, ia caeaaeii a?ae aa??aioo aioeoae?eiaaeoa?ii? oa?ai??. Ioaea, aioeoae?eiaaeoa?ia oa?ai?y oa a?aaeeeaoe?y NI aano?i-aeoiaeaiaeueii? ciie a?ae I? ciaioothoue aeoeai?noue AA oa aeoiaeai?oo oa iiceoeaii aieeaathoue ia oa?aeoa? ia?aa?ao noiooi?o aeene?iac?e AEI o oai?eo ia AO AeIE. Io?eiai? iaie aeai? aeiaiaeyoue aca?iica”ycie nei?i/oaaeueii? ooieoe?? AEI oa ii?oieia?/iiai noaio NI aano?iaeoiaeaiaeueii? ciie, a oaeiae i?aeoaa?aeaeothoue ia o?eueee aeoieo aaaaoueio aeine?aeiee?a i?i iaoiaaiaoe/io ?ieue I? a ?icaeoeo ii?oieia?/ieo ci?i NI aano?iaeoiaeaiaeueii? ciie o oai?eo ia AOAeIE , a e ?oith ?ieue a ?icaeoeo noiooi?o aeene?iac?? AEI. AENIIAEE 1.Na?aae 130 oai?eo ia AOAeIE anoaiiaeaii, ui ii?iie?iac?y AEI niinoa??aaeanue o 23,8% ianoaaeaieo, a?ia?e?iaoe/ia aeene?iac?y AEI o 43,1% iaoe??io?a, a a?iie?iaoe/ia oi?ia aeene?iac?? -o 33,1% in?a, o./. o 76,2% oai?eo aeyaeai? aeene?iac?? AEI. 2.Iayai?noue noiooi?o aeene?iac?e iicaia/?ieiaeo aeia/iaea?aeieo oeyo?a aieeaa? ia nooi?iue aaaeeino? ia?aa?ao AOAeIE. *anoioa oa oei aeene?iac?? AEI caeaaeaoue a?ae o?eaaeino? caoai?thaaiiy ia AOAeIE oa a?eo oai?eo: i?e ae?aceiaiio aiaiiaco aei 5 ?ie?a oa o iaoe??io?a aei 50 ?ie?a ia?aaaaea? a?ia?e?iaoe/ia aeene?iac?y, a i?e o?eaaeino? caoai?thaaiiy a?eueoa 5 ?ie?a oa o iaoe??io?a a?eii a?eueoa 50 ?ie?a ia?aaaaea? a?iiiioi?ia aeene?iaic?y AEI. 3. O an?o ianoaaeaieo oai?eo aeyaeaii AA oa aeoiaeai?o, nooi?iue aaaeeino? yeiai aca?iica”ycaiee c? nooiaiai ?io?eiaaiino? Ielicobacter pylori. 4. I?e caaino?aii? AOAeIEa I-ee?oeiao NI AeIE a?aeaoaathoueny aeano?oeoeai? ci?ie, ye? iiai?noth ia a?aeiiaeththoueny iaa?oue a ia??iae ?ai?n?? AOAeIE. 5. O 84,6 % oai?eo anoaiiaeaia ?io?eiaai?noue I?, can?yi?noue I? ? no. a?aecia/aeanue na?aae 33,6% ianoaaeaieo, ?? no.- o 48,2% in?a, a ?io?eiaai?noue I? ??? no. niinoa??aaeanue o 18,2% iaoe??io?a. 6.Ii i??? c?inoaiiy aaaeeino? AA e aeoiaeai?oo oa nooiaiy can?yiino? NI aano?iaeoiaeaiaeueii? ciie I? ca?eueoo?ueony e?euee?noue iaoe??io?a c noiooi?ie aeene?iac?yie AEI, a oaeiae ci?ith?oueny ?o oa?aeoa?: ciaioo?oueny e?euee?noue niinoa?aaeaiue a?ia?iioi?ii? oi?ie oa ca?eueoo?oueny e?euee?noue a?iiiioi?ii? aeene?iac?? AEI. 6.Aioeoae?eiaaeoa?ia oa?ai?y oa a?aaeeeaoe?y NI aano?iaeoiaeaiaeueii? ciie a?ae I? ciaioothoue aeoeai?noue AA oa aeoiaeai?oo, iiceoeaii aieeaathoue ia oa?aeoa? ia?aa?ao noiooi?o aeene?iac?e AEI. 7.A eiiieaenia e?eoaaiiy aeene?iac?e AEI o oai?eo c o?aaeaiiyie NI aano?iaeoiaeaiaeueii? ciie iaiao?aeii aeeth/aoe i?aia?aoe, ni?yiiaai? ia a?aaeeeaoe?th I? oa ii?iae?caoe?th ?? a?noieia?/iiai noaio. I?AEOE*I? ?AEIIAIAeAOe?? 1. C iaoith ae?aaiinoeee aeene?iac?e AEI ioe?iea eiai iioi?ii-aaaeoaoi?ii? ooieoe?? iiaeiia i?iaiaeeoenue /a?ac aecia/aiiy ia”?io oa eiao?oe??ioo nii?iaeiaiiy AEI. Eiao?oe??io nii?iaeiaiiy a?eueoa 66% na?ae/eoue i?i a?ia?e?iaoe/io aeene?iac?th AEI, a iaioa 33% - a?iie?iaoe/io oi?io aeene?iac??. 2.I?e aeene?iac?yo iicaia/?ieiaeo aeia/iaea?aeieo oeyo?a aeey caaacia/aiiy aaeaeaaoiiai iaoiaaiaoe/iiai e?eoaaiiy iio??aii aecia/aoe nooi?iue o?aaeaiiy NI aano?iaeoiaeaiaeueii? ciie oa nooi?iue can?yiino? ?? H?. Iiceoeaiee aoaeo ei?aeoe?? aeene?iac?e aeia/iiai i?oo?a iiaeia io?eiaoe i?e AA ? oa ?? no. oa ?io?eiaaiino? I? ? oa ?? no. 3.A eiiieaenia e?eoaaiiy aeene?iac?e iicaia/?ieiaeo aeia/iaea?aeieo oeyo?a o oai?eo c o?aaeaiiyie NI aano?iaeoiaeaiaeueii? ciie iaiao?aeii aeeth/aoe i?aia?aoe, ni?yiiaai? ia a?aaeeeaoe?th I? oa ii?iae?caoe?th ?? a?noieia?/iiai noaio. Ca iaoeie aeaieie, a oeeo aeiaaeeao iaea?eueo aaeaeith ? eiia?iaoe?y iiai?icieo a oaae. ii 20 ia 1-2 ?ace ia aeiao 2 oeaei? oa aiien?oeee?i 750 ia+ iao?ii?aeacie 500ia a oaae. 3 ?ace ia aeiao 10 aei?a. Ae?OEIAAI? ?IAIOE CA OAIITH AeENA?OAOe?? 1.Eeeiaineay I.A., Iaaci?ia A.I. Noaiee?ineiie/aneay i?aaiecaoeey ?-eeaoie o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee //Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.- 1998.-? 21.- N. 28-32. 2. Eeeiaineay I.A., I?eianeee A.O. Acaeiinaycue nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y e ii?oieiae/aneiai ninoiyiey neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu e aa ianaiaiaiiinoe Helicobacter pylori o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee // A?a/aaiia aeaei. -1998.- ? 8.- N. 79-83. 3. Eeeiaineay I.A. Aeeyiea aioeoaeeeiaaeoa?iie oa?aiee ia ii?oieiae/aneia ninoiyiea neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu e oa?aeoa? aeeneeiacee aeae/iiai iocu?y o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu .- 1999.- ? 2.- N. 44-48. 4. I?eianeee A.O., Eeeiaineay I.A., Eica A.E., I?ieiieoae I.A. I?ioeai?aoeeaeeaiay yooaeoeaiinoue aioeaaeoa?eaeueiie oa?aiee ycaaiiie aieacie aeaaiaaeoeaoeia?noiie eeoee oaeeeiaaeoa?iie yoeieiaee //Oace aeiiia?aeae ?? Oe?a?inueeiai oeaeiy aano?iaioa?ieia?a, 23-25 aa?aniy 1997 ?., Aei?i?iiao?ianuee, - Aei?i?iiao?ianuee, 1997- N. 98. 5. I?eianeee A.O., Eeeiaineay I.A., Eica A.E. Oa?aeoa? iioi?iie ooieoeee aiaia/aii/iuo aeae/iuo iooae a caaeneiinoe io ii?oieiae/aneiai ninoiyiey neecenoie iaiei/ee aio?aeueiiai ioaeaea aeaeoaeea e aeaaiaaeoeaoeia?noiie eeoee o aieueiuo ycaaiiie aieaciueth aeoiaeaiaeueiie eieaeecaoeee //?inneeneee aeo?iae aano?iyioa?ieiaee, aaiaoieiaee, eieii?ieoieiaee. I?eeiaeaiea ? 4 Iaoa?eaeu O?aoueae ?inneeneie Aano?iyioa?ieiae/aneie Iaaeaee, 15-21 iiya?y 1997a.,Iineaa.-I., 1997- O.7.-? 5.- N. 176. 6. I?eianeee A.O., Eeeiaineay I.A. Ii?oieiaey neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu e nie?aoeoaeueiay ooieoeey aeae/iiai iocu?y o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee // Iaoa??aee iaoeiaeo i?aoeue ?anioae?eainueei? iaoeiai-i?aeoe/ii? eiioa?aioe?? “Aeinyaiaiiy oa iaae??oai? ieoaiiy aano?iaioa?ieia?? ”, 7-8 ea?oiy 1998 ?.,Oa?e?a, - Oa?e?a, 1998- N.134. AIIOAOe?ss Eeeiainueea I.A. Aca?iica”ycie nei?i/oaaeueii? ooieoe?? aeia/iiai i?oo?a oa ii?oieia?/iiai noaio neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie.- ?oeiien. Aeena?oaoe?y ia caeiaoooy a/aiiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14. 01. 02.-aioo??oi? oai?iae.-Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I. E.Uoieea I?i?noa?noaa ioi?iie caei?ia”y Oe?a?ie, Eeia, 1999. Caoeua?oueny aeena?oaoe?y, a ye?e aeine?aeaeoaaeenue oa iaaiai?thaaeenue aeai? i?i aca?iica”ycie nei?i/oaaeueii? ooieoe?? aeia/iiai i?oo?a oa ii?oieia?/iiai noaio neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie oa ?? can?yiino? Helicobacter pylori o oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee. Aeai? caeiaoo? ca aeiiiiiaith oeueo?acaoeiaiai aeine?aeaeaiiy nei?i/oaaeueii? ooieoe?? aeia/iiai i?oo?a c canoinoaaiiyi aeia/iaiiiiai ni?aeaieo, ii?ioieia?/iiai oa ii?oiiao?e/iiai aeine?aeaeaiiy a?iioao?a neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie i?ney ?o oa?aoaaiiy aaiaoienee?i-aiceiii, ye? aoee iaea?aeai? i?ae /an oia?iacioaaiaano?iaeoiaeaiineii??; iayai?noue oa nooi?iue can?yiino? I? aio?aeueiiai a?aeae?eo oeoiea aecia/aee ii?oieia?/iei iaoiaeii i?ney oa?aoaaiiy a?iioao?a ca ?iiaiianueeei - A?icith; aeaeo?iiii? i?e?ineii?? aiaeie?eiieo ?-ee?oei neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie. Aeiaaaeaii aca?iica”ycie nei?i/oaaeueii? ooieoe?? aeia/iiai i?oo?a oa nooiaiy aaaeeino? aio?aeueiiai aano?eoo oa aeoiaeai?oo, aaaee?noue yeeo iaoiiaeth?oueny nooiaiai ?io?eiaaiino? neeciai? iaieieiee Helicobacter pylori. Anoaiiaeaii, ui aioeoae?eiaaeoa?ia oa?ai?y oa a?aaeeeaoe?y neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie a?ae Helicobacter pylori ciaioothoue aeoeai?noue aio?aeueiiai aano?eoo oa aeoiaeai?oo, iiceoeaii aieeaathoue ia oa?aeoa? ia?aa?ao noiooi?o aeene?iac?e. A eiiieaenia e?oeaaiiy noiooi?o aeene?iac?e aeia/iiai i?oo?a o oai?eo c o?aaeaiiyie neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie ?aeiiaiaeiaaii aeeth/aoe i?aia?aoe,ni?yiiaai? ia a?aaeeeaoe?th Helicibacter pylori oa ii?iae?caoe?th ?? a?noieia?/iiai noaio. Eeth/ia? neiaa: ae?aceiaa oai?iaa aeaaiaaeoeyoeiaei? eeoee, aio?aeueiee aano?eo, aeoiaeaiio, Helicobacter pylori, aeia/iee i?oo?, aeeneiiaciy, aiaeie?eii? ?-ee?oeie, aioeoae?eiaaeoa?i? caniae. ANNOTATION Klimanskay N.V. Interaction of contractive function of gallbladder and morphological state of gastroduodenal zone mucous membrane.- Manuscript. The dissertation for the completion of the candidate of medical science degree on the speciality 14.01.02-internal diseases. Kyiv Medical Academy of Post-Graduated Education named after P. Shupyk. Health Ministry of Ukraine, Kyiv, 1999. The dissertation in which the data on dependence of contractive function of gallbladder on morphological state of gastroduodenal zone mucous membane & its contemination with Helicobacter pylori in duodenal ulcer patients are investigated. The data have been obtained with the help of supersonic tests made on gallbladder contractive function in the experiment bilious breakfast was used & the following stages were provided; morphological & morphometrical research on mucous membrane bioptate after its coloring with gematocsilin-iozin; the level of Helicobacter pylori contemination in the antral unit of stomach was determined on the basis of histological methods ( after coloring the bioptate as to Romanovsky-Gimze); electronic microscopy of endocrine I-cells of duodenal mucous membrane was made. The dependence of contractive function of gallbladder on antral gastritis, duodenit & the level of their complications was proved, with their function being in proportional dependence on Helicobacter pylori contemination of duodenal mucous membrane. It was established that antihelicobacter therapy & eradication of Helicobacter pylori from gastroduodenal mucose membrane reduces antral gastritis & duodenit effect & positively affect the character of attendant gallbladder. In the complex treatment of patients with attedant gallbladder dyskinesias & gastroduodenal mucoae membrane damage it is necessary to use medication aimed at Helicobacter pylori eradication until its gistological state is normal. Key words: duodenal ulcer, antral gastritis, duodenit, Helicobacter pylori, gallbladder, dyskinesia, endocrin I-cell, antihelicobacter preparations. AIIIOAOeEss Eeeiaineay I.A. Acaeiinaycue nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y e ii?oieiae/aneiai ninoiyiey neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu.- ?oeiienue. Aeena?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.0.02-aioo?aiiea aieacie. Eeaaneay iaaeeoeeineay aeaaeaiey iineaaeeieiiiiai ia?aciaaiey ei. I. E. Uoieea Ieienoa?noaa cae?aaiio?aiaiey Oe?aeiu, Eeaa, 1999. Caueuaaony aeenna?oaoeey, a eioi?ie enneaaeiaaiu e ianoaeaeaiu aeaiiua i acaeiinayce nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y e ii?oieiae/aneiai ninoiyiey neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu e aa ianaiaiaiiinoe Helicobacter pylori o aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. Aeaiiua iieo/aiu n iiiiuueth oeueo?acaoeiaiai enneaaeiaaiey nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y n eniieueciaaieai aeae/aaiiiiai caao?aea, ii?oieiae/aneiai e ii?oiiao?e/aneiai enneaaeiaaiey aeiioaoia neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu iinea eo ie?anee aaiaoieneeei-yiceiii; noaiaiue ianaiaiaiiinoe Helicobacter pylori aio?aeueiiai ioaeaea aeaeoaeea ii?aaeaeyee aenoieiae/aneei iaoiaeii iinea ie?anee aeiioaoia ii ?iiaiianeiio-Aeica; yeaeo?iiiie iee?ineiiee yiaeie?eiiuo I-eeaoie neecenoie iaiei/ee aeaaiaaeoeaoeia?noiie eeoee. Auei ianeaaeiaaii 130 aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. I?e eco/aiee nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y onoaiiaeaii, /oi ii?iieeiacey aeae/iiai iocu?y ioia/aeanue o 23,8% ianeaaeiaaiiuo, n?aaee 76,2% aieueiuo auee auyaeaiu ia?ooaiey nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y: aeia?eeiaoe/aneay aeeneeiacey ?aaeno?e?iaaeanue o 43,1% eeoe, a aeiieeiaoe/aneay oi?ia aeeneeiacee -o 33,1% iaoeeaioia. Onoaiiaeaii, /oi i?e ycaaiiii aiaiiaca aei 5 eao e o aieueiuo aei 50 eao i?aiaeaaeaea aeia?eeiaoe/aneay aeeneeiacey aeae/iiai iocu?y, a i?e aeeeoaeueiinoe caaieaaaiey aieueoa 5 eao e aic?anoa iaoeeaioia noa?oa 50 eao i?aiaeaaeaea aeiieeiaoe/aneay aeeneeiacey aeae/iiai iocu?y. I?e ii?oieiae/aneii enneaaeiaaiee aio?aeueiue aano?eo ? no. ioia/aeny o 35,4% aieueiuo, ??no. -o 46,1% ianeaaeiaaiuo e o 18,5% eeoe auyaeai aio?aeueiue aano?eo ???no. Oia?aiii au?aaeaiiue aeoiaeaieo ?aaenoe?iaaeny o 31,5% ianeaaeiaaiiuo, au?aaeaiiue aeoiaeaieo aue auyaeai n?aaee 52,3% aieueiuo, a ao?ioe/aneee aeoiaeaieo iaaethaeaeny o 16,2% iaoeeaioia. O 84,6% aieueiuo auea auyaeaia ianaiaiaiiinoue Helicobacter pylori. Ianaiaiaiiinoue I?Ino. ioia/aeanue o 33,6% aieueiuo, eioaoee?iaaiiinoue IIno.-o 48,2% ianeaaeiaaiiuo, a ianaiaiaiiinoue I? IIIno.-n?aaee 18,2% iaoeeaioia. O aieueiuo n aio?aeueiui aano?eoii I no. a 47,8 % neo/aaa ioia/aeanue aeia?eeiaoe/aneay aeeneeiacey aeae/iiai iocu?y, ii?iieeiacey - o 52,2% ianeaaeiaaiiuo. N?aaee iaoeeaioia n aio?aeueiui aano?eoii II no. aeia?eeiaoe/aneay aeeneeiacey aeae/iiai iocu?y ?aaeno?e?iaaeanue o 56,7% eeoe, a o 31,7% iaoeeaioia -aeiiiioi?iay oi?ia aeeneeiacee aeae/iiai iocu?y e oieueei o 11,6% aieueiuo ioia/aeanue ii?iaeueiay nie?aoeoaeueiay ooieoeey aeae/iiai iocu?y.O anao aieueiuo n ao?ioe/aneei aano?eoii auea auyaeaia aeiiiioi?iay aeeneeiacey aeae/iiai iocu?y. Aeieacaia acaeiinaycue nie?aoeoaeueiie ooieoeee aeae/iiai iocu?y e noaiaie oyaeanoe aio?aeueiiai aano?eoa e aeoiaeaieoa, aeoeaiinoue eioi?uo ii?aaeaeyaoueny noaiaiueth ianaiaiaiiinoe neecenoie iaiei/ee Helicobacter pylori. I?e aeaeoi?iiiie iee?ineiiee onoaiiaeaii, /oi oeueo?ano?oeoo?iua eciaiaiey aiaeie?eiiuo I-eeaoie neecenoie iaiei/ee aeaaiaaeoeaoeia?noiie eeoee a ia?eiae ?aiennee iineee aeeno?ioe/aneee oa?aeoa?. /oi naeaeaoaeuenoaoao i nieaeaiee o?iaiy neioaca oieaoeenoieeieia-iaie?aiceieia. A ioaeaeueiuo eeaoeao ioia/aeenue i?ioeannu ooieoeeiiaeueiiai iai?yaeaiey e oneeaiey ?aia?aoeaiuo ?ioeannia. O aieueiuo ycaaiiie aieaciueth a ia?eiae iaino?aiey aeeno?ioe/aneea ia?ooaiey eciaiyeenue a noi?iio aeano?oeoeaiuo, /oi no?oeoo?ii au?aaeaeinue eecenii o/anoeia yaea?iie iaia?aiu, aiaoiae iaia?aiu ieoioiiae?ee e e?eno, iaia?ai a?aioey?iie yiaeiieaciaoe/aneie naoe, e, eae neaaenoaea yoiai ioia/aeinue ?aceia nieaeaiea eiee/anoaa nae?aoi?iuo a?aioe. Neaaeiaaoaeueii, iaee/ea aeano?oeoeaii-aeeno?ioe/aneeo i?ioeannia a I-eeaoeao neecenoie iaiei/ee aeaaiaaeoeaoeia?noiie eeoee, eioi?ua ia ainnoaiaaeeaathoueny aeaaea a ia?eiae ?aiennee, iiaeao neoaeeoue ioneiaui iaoaieciii ?acaeoey niioonoaothueo aeeneeiacee aeae/iiai iocu?y o aieueiuo ycaaiiie aieaciueth. Onoaiiaeaii, /oi aioeoaeeeiaaeoa?iay oa?aiey e y?aaeeeaoeey neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu io Helicobacter pylori oiaiueoatho aeoeaiinoue aio?aeueiiai aano?eoa e aeoiaeaieoa e iiceoeaii aeeytho ia oa?aeoa? oa/aiey niioonoaothueo aeeneeiacee aeae/iiai iocu?y. A eiiieaeniia ea/aiea niioonoaothueo aeeneeiacee aeae/iiai iocu?y o aieueiuo n ii?aaeaieyie neecenoie iaiei/ee aano?iaeoiaeaiaeueiie ciiu ?aeiiaiaeoaony aeeth/aiea i?aia?aoia, iai?aaeaiiuo ia y?aaeeeaoeeth Helicobacter pylori e ii?iaeecaoeeth aa aenoieiae/aneiai ninoiyiey. Eeth/aaua neiaa: ycaaiiay aieaciue aeaaiaaeoeaoeia?noiie eeoee, aio?aeueiue aano?eo, aeoiaeaieo, Helicobacter pylori, aeae/iue iocu?ue, aeeneeiacey, yiaeie?eiiua I-eeaoee, aioeoaeeeiaaeoa?iay oa?aiey.

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