I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

OE?A?INUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO

EA?Ae?IEIA?? ?I. AEAAe. I.Ae.NO?AAEANEA

*oao/ia ??eia ?aai?aia

OAeE: 616.127 – 005.8 – 036.82.86 – 085

AIEEA OA?AI?? ANI??EIII OA NO?AIOIE?IACITH IA A?AeIIAEAIIss NENOIE?*II?
OOIEOe?? NA?Oess, AeEIAI?EO II?OOAIUe NA?OeAAIAI ?EOIO OA ?OAI?? O
OAI?EO, UI I?IOIAeEEE I?ENEI?AIO I?IA?AIO ?AAA?E?OAOe?? I?NEss
IA?AIANAIIAI ?IOA?EOO I?IEA?AeA

14.01.11 – ea?ae?ieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1999

Aeena?oaoe?y ? ?oeiienii

?iaioa aeeiiaia a Oe?a?inueeiio iaoeiai-aeine?aeiiio ?inoeooo?
ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea IIC Oe?a?ie

Iaoeiaee ea??aiee:

aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee Ooiaeia Aaeaioei
Ieaenaiae?iae/, caa?aeoaa/ a?aeae?eaiiy ?ioa?eoo i?iea?aea oa
a?aeiiaethaaeueiiai e?eoaaiiy Oe?a?inueeiai iaoeiai-aeine?aeiiai
?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea IIC Oe?a?ie

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani? Aaiaeao sse?a Aa?aiiae/, aieiaiee
iaoeiaee ni?a?ia?oiee a?aeae?eo iaaooeo aaae na?oey ?inoeoooo
na?oeaai-noaeeiii? o??o?a?? AII Oe?a?ie, i.Ee?a

aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee Ia?oiiaiei
Ieaenaiae? Ieeieaeiae/, caa?aeoaa/ a?aeae?eaiiy ?aai?iaoe?? oa
?ioaineaii? oa?ai?? Oe?a?inueeiai iaoeiai-aeine?aeiiai ?inoeoooo
ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea IIC Oe?a?ie

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i.
I.I.Aiaiiieueoey IIC Oe?a?ie, eaoaae?a oaeoeueoaonueei? oa?ai?? ? 2

Caoeno a?aeaoaeaoueny “27” ea?oiy 1999 ?ieo i 12-00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.616.01 i?e Oe?a?inueeiio
iaoeiai-aeine?aeiiio ?inoeooo? ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea
(252151, i. Ee?a, aoe. Ia?iaeiiai Iiie/aiiy, 5)

C aeena?oaoe??th iiaeia iciaeiieoeny a a?ae?ioaoe? Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea
(252151, i. Ee?a, aoe. Ia?iaeiiai Iiie/aiiy, 5)

Aaoi?aoa?ao ?ic?neaiee “26” aa?aciy 1999 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Aeaye N.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. Aino?ee iioa?eo iiiea?aea (II) ? caa?iceeaei aeey
aeeooy o?aaeaiiyi na?oey, yea cia/iith ii?ith aecia/a? caaaeueio
nia?oiinoue aiae na?oeaai-noaeeiieo caoai?thaaiue. Aenieee ?ecee
caoai?thaaiiy oa iiaaeiaeecaoei? inia i?aoeacaeaoiiai aieo i?ecaiaeeoue
aei ia?a?inoaiiy oei?? i?iaeaie ic aeania ea?aeiieiai/ii? /e iaaioue
iaaee/ii? a nioeiaeueio. A ca’yceo c oeei ia i?ioyci eieueeio aeanyoe?i/
i?iaiaeeeinue iioaineaia aea/aiiy aino?eo oi?i ION oa canoinoaaiiy
iaoiaaiaoe/ieo iaoiaeia oa?iaeieiai/ii? ei?aeoei?, cie?aia
o?iiaieioe/ii? oa?aii?, aioeeiaaoeyioia oa aioeaa?aaaioia, ui aeicaieeei
cia/ii cieceoe eaoaeueiinoue aiae II oeyoii ciaioaiiy ciie iae?ico,
iiia?aaeaeaiiy ?icaeoeo aiaa?ecie na?oey, a?eoiie, aino?i? na?oeaai?
iaaeinoaoiinoi, ea?aeiiaaiiiai oieo, oiaoi iniiaieo i?e/ei eaoaeueiinoi
oa oneeaaeiaiiai ia?aaiao II. O ?acoeueoaoi nia?oiinoue aiae aino?iai II
cieceeanue c 20% ia ii/aoeo 70-o ?ieia aei 7-8% o aeaiee /an o
iaeaieueoeo naioiaeo ea?aeiieiai/ieo oeaio?ao [GISSI, 1986, ISIS-2,
1990, ISIS-3, 1992, GUSTO, 1993].

O oie aea /an, oniioe iaaiaeeeaaeii? ea?aeiieiai? iiaeiyee ?yae iiaeo
i?iaeai. Ia?o ca ana, oai?i iiney ia?aianaiiai II, yei o aieueoinoi
aeiaaeeia ?aiioa ia?aoiaeeee ia iiaaeiaeiinoue, ii/aee ana /anoioa
iiaa?oaoeny aei aeoeaii? o?oaeiai? aeiyeueiinoi, ui aeiaaaei ?ic?iaee
i?eioeeiia oice/ii?, o?oaeiai? i nioeiaeueii? ?aaaieioaoei? [H.Denolin,
1985, A.I.Aeueoeiiae/, 1987, A.?.Eacaeia, 1995, I.E.Neaaecaanea, 1995,
A.Villela, 1995].

Iiai oaoiieiai? eieoaaiiy aino?iai II iai?aaeaii ia aiaeiiaeaiiy
aiioeaaiai e?iaiiaiao o ia?oi aiaeeie iiney ?icaeoeo eeiii/ii? ea?oeie
caoai?thaaiiy oa ia caiiaiaaiiy iiaoi?iiai ei?iia?iiai o?iiaico o
aino?iio oa ?aaaieioaoeieiiio ia?iiaeao II (Dietrich C. Gulbe, 1997,
Aiiniaa A.I., 1998). Canoinoaaiiy o?iiaieioe/ii? oa?aii? noaei iaeaea
?ooeiiith i?ioeaaeo?ith o i?aeoe/iie iaaeeoeeii ?icaeiooeo e?a?i naioo.
Oae, i?iaaaeaiee a ia?oo aiaeeio caoai?thaaiiy, o?iiaieicen ?yoo? 35
aeeooia ia 100 oai?eo ia II ai?iaeiaae ainiioaeueiiai ia?iiaeo,
i?iaaaeaiee o ia?oi 6 aiaeei — aei 20 oai?eo.

Caaaeyee oeei ?acoeueoaoai c’yaeeany oai?aoe/ia iiaeeeainoue i?enei?eoe
oaiie ?icoe?aiiy ?ooiaiai ?aaeeio oa oice/ii? ?aaaieioaoei? o oei??
eaoaai?i? oai?eo. Aea inio?, ye iiiiioi, aeai i?iaeaie: ii-ia?oa, aeey
i?enei?aiiai ?icoe?aiiy ?ooiaiai ?aaeeio iiaeiii inioaaoe ia?aaeoiiae,
oaei, ye aiaenooiinoue ioaii/ieo aiiciaeia ia AEA, caa?iceeaeo ii?ooaiue
?eoio oa eeiii/ieo i?iyaia na?oeaai? iaaeinoaoiinoi, a oaeiae
caaeiaieueii iieacieee nenoaiii? oa aioo?ioiueina?oeaai? aaiiaeeiaiiee,
ii-ae?oaa, i?enei?aiee ?aaeei ia iiaeiai iiai?oeoe oei iieacieee. O yeeo
oai?eo ia aino?ee II oa a yei oa?iiie caoai?thaaiiy iiaeia canoiniaoaaoe
“iioaineaio” ?aaaieioaoeith, ye aiia iicia/a?oueny ia ooieoeiiiaeueiiio
noaii na?oeaaiai i’yca oa ei?iia?iiio e?iaiiaiao aeini caeeoa?oueny
iaaiaeiii.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Ia?aiee
iai?yiie aeineiaeaeaiue ? /anoeiith aeineiaeaeaiiy, yea i?iaiaeeeiny o
aiaeaeieaiii iioa?eoo iiiea?aea oa aiaeiiaethaaeueiiai eieoaaiiy
Oe?a?inueeiai iaoeiai-aeineiaeiiai iinoeoooo ea?aeiieiai? ii. aeaae.
I.Ae.No?aaeanea i ? neeaaeiaith /anoeiith caeeth/iiai caioo aiaeaeieaiiy
i?i iaoeiai-aeineiaeio ?iaioo ca 1992 — 1994 ??. “?ic?iaeoe iiai
oaoiieiai? a aeiaaiinoeoei, eieoaaiii oa ?aaaieioaoei? oai?eo c aino?eie
ii?ooaiiyie ei?iia?iiai e?iaiiaiao oa ii?ooaiiyie na?oeaaiai ?eoio” (?
aea?ae. ?a?no?aoei? A01008394?)

Iaoa i caaea/i aeineiaeaeaiiy. Aea/eoe ciiie aioo?ioiueina?oeaai?
aaiiaeeiaiiee, ?iaaiue ei?iia?iiai ?aca?ao i oiea?aioiinoue aei
oice/iiai iaaaioaaeaiiy o oai?eo c aino?ei iioa?eoii iiiea?aea iiney
o?iiaieioe/ii? oa aioeaa?aaaioii? oa?aii? i?e i?enei?aiie oice/iie
?aaaieioaoei?. C aeaii? iaoe aeieeaathoue ianooiii caaea/i:

1. Aecia/eoe aieea o?iiaieioe/ii? oa?aii? i i?eeiio anii?eio ia
iieacieee nenoiei/ii? ooieoei? eiaiai oeoii/ea o oai?eo, ui ia?aianee
aino?ee iioa?eo iiiea?aea i?ioyaii 6 iinyoeia.

2. Aeineiaeeoe aieea o?iiaieioe/ii? oa?aii? i i?eeiio anii?eio ia iiyao
ii?ooaiiue ?eoio o oai?eo iiney aino?iai iioa?eoo iiiea?aea i?ioyaii 6
iinyoeia.

3. Aecia/eoe aieea o?iiaieioe/ii? oa?aii? i i?eeiio anii?eio ia i?iyae
ioaii? iiiea?aea o oai?eo iiney aino?iai iioa?eoo iiiea?aea i?ioyaii 6
iinyoeia.

4. Aecia/eoe cia/oui oaeoi?e aeieeiaiiy ?aioiai? ei?iia?ii? nia?oi,
ioaii? oa na?oeaai? iaaeinoaoiinoi.

5. Aecia/eoe iiaeeeainoue i?enei?aiiy aiaeiiaeaiiy i?aoeacaeaoiinoi
i?ioyaii 0.5 ?ieo o oai?eo aino?ei iioa?eoii iiiaea?aea iiney oa?aii?
no?aioieiiacith oa anii?eiii.

Haoeiaa iiaecia iaea?aeaieo ?acoeueoaoia. Anoaiiaeaii oiniee
ei?aeyoeieiee ca’ycie iiae noia?iith o?eaaeinoth ioaii? i?e aeiaiaiio
iiiioi?oaaiii AEA, o?aeoei?th aeeeaeo i ?iaiai aeeiiaii? ?iaioe a ia?oi
aeii aino?iai iioa?eoo iiiea?aea. Aia?oa aecia/aii e?eoa?i? ?aiiueiai
aeiciaaiiai oice/iiai iaaaioaaeaiiy o oai?eo c ainoei iioa?eoii
iiiea?aea, i?iaiinoe/ii iani?eyoeeai o aiaeiioaiii ?icaeoeo ?aioiai?
ei?iia?ii? nia?oi, na?oeaai? iaaeinoaoiinoi oa iiaoi?ieo ei?iia?ieo
aoae. Anoaiiaeaii, ui oa?aiiy no?aioieiiacith oa anii?eiii aeicaiey?
aacia/ii i?iaiaeeoe i?enei?aio i?ia?aio oice/ii? ?aaaieioaoei? oai?eo
iioa?eoii iiiea?aea.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoaoia. Ia??oiooaaee aaaeeeainoue
?aiiueiai i?ecia/aiiy o?iiaieioe/ii? oa?aii? i anii?eio oai?ei ia
aino?ee iioa?eo iiiea?aea aeey i?enei?aiiy aiaeiiaeaiiy nenoiei/ii?
ooieoei? eiaiai oeoii/ea, cieaeaiiy eiiai?iinoi aeieeiaiiy
iineyiioa?eoii? noaiiea?aei? i ii?ooaiue ?eoio. Ia??oiooaaee
iiaeeeainoue i?enei?aii? i?ia?aie ?aaaieioaoei? o oai?eo ia aino?ee
iioa?eo iiiea?aea, o yeeo aoea i?iaaaeaia o?iiaieioe/ia oa?aiiy i
canoiniaoaaany anii?ei. Ciaioeee /an ia?aaoaaiiy oai?iai o noaoeiiia?i,
cieceee oei/aniao iai?aoeacaeaoiinoue oa iiaaeiaeiinoue iiney iioa?eoo
iiiea?aea oeyoii canoinoaaiiy o?iiaieioe/ii? oa?aii? oa anii?eio.

Ai?iaaaeaeaiiy ?acoeueoaoia aeineiaeaeaiiy a i?aeoeeo. ?acoeueoaoe
aeineiaeaeaiiy ai?iaaaeaeaii a i?aeoeeo ?iaioe iioa?eoiiai aiaeaeieaiiy
Eueaianueeiai iaeaniiai ea?aeiieiai/iiai oeaio?o, aiaeaeieaiiy iioa?eoo
iiiea?aea oa aiaeiiaeiaaeueiiai eieoaaiiy Oe?a?inueeiai
iaoeiai-aeineiaeiiai iinoeoooo ea?aeiieiai? ii. aeaae. I.Ae.No?aaeanea,
iioa?eoiiai aiaeaeieaiiy eiea?ii oaeaeei? aeiiiiiae i.Ee?aa.

Iniaenoee aianie caeiaoaa/a. Aianie caeiaoaa/a a io?eiaiiy iaoeiaeo
?acoeueoaoia ? iniiaiei i iieyaa? a iniaenoiio i?iaaaeaiii nooo?aiai
ia’?io eeiii/ieo oa iino?oiaioaeueieo aeineiaeaeaiue, a aiaeici,
ocaaaeueiaiii oa ia?iaoei ?acoeueoaoia aeineiaeaeaiiy, iiaeaioiaoei aei
ae?oeo iaeyaeiaeo oa i?eaiiaeueieo noaoae, ioi?ieaiii aeena?oaoeieii?
?iaioe oa aaoi?aoa?aoo.

Ai?iaaoeiy ?acoeueoaoia aeena?oaoei?. Iniiaii iieiaeaiiy aeena?oaoei?
aeiiiaiaeaeeny oa iaaiai?thaaeenyi ia caniaeaiii Iaeanueeiai iaeaniiai
oiaa?enoaa ea?aeiieiaia (Iaeana, 1995), ia Ieaioii i?aaeiiiy
Oe?a?inueeiai iaoeiaiai oiaa?enoaa ea?aeiieiaia «Aino?a oa o?iii/ia
na?oeaaa iaaeinoaoiinoue, ?aioiaa nia?oue» (Aiiieoey, 1995), caniaeaiii
Eueaianueeiai iaeaniiai oiaa?enoaa ea?aeiieiaia (Eueaia, 1996), V
Eiia?ani ea?aeiieiaia Oe?a?ie (Ee?a, 1997), ae?oaiio iiaeia?iaeiiio
c’?caei c na?oeaai? iaaeinoaoiinoi (Na?oeaaa Iaaeinoaoiinoue-97, Eaeuei,
1997).

Ioaeieaoei?. Iaoa?iaee aeena?oaoei? aenaioeaii a 13 ioaeieaoeiyo (6-oe
noaooyo o iaoeiaeo aeo?iaeao i 7 oacao aeiiiaiaeae).

No?oeoo?a aeena?oaoei?. Iaoa?iaee aeena?oaoei? aeeeaaeaii ia 139
noi?iieao ae?oeiaaiiai oaenoo, iethno?iaaii 21 ?enoieii oa 26 oaaeeoeyie
i neeaaeathoueny ci anooio, iaeyaeo eioa?aoo?e, i’yoe ?icaeieia aeanieo
aeineiaeaeaiue, caeeth/aiiy, aeniiaeia, i?aeoe/ieo ?aeiiaiaeaoeie.
Nienie aeei?enoaii? eioa?aoo?e iinoeoue 212 aeaea?ae, c yeeo 43
aio/eciyieo oa 169 ca?oaiaeieo.

INIIAIEE CIINO ?IAIOE

Iaoa?iaee oa iaoiaee aeineiaeaeaiiy

A ianoaaeaiiy aoei aeeth/aii 127 oai?eo (/ieiaieia) c iaoneeaaeiaiei
iioa?eoii iiiea?aea o aioei aiae 21 aei 70 ?ieia (na?aaeiie aie oai?eo
noaiiaea 46.3+3.1 ?ieia), yei eieoaaeeny a iioa?eoiiio aiaeaeieaiii
Eueaianueeiai iaeaniiai ea?aeiieiai/iiai oeaio?o a ia?iiae c 1993 ii
1995 ?ie.

Oni aeeth/aii a ianoaaeaiiy iaoei?ioe iaeaaeaee aei 1-2 eeano ca
Eieeiiii: 80 — aei ia?oiai, a 47 — aei ae?oaiai eeano. O oai?eo ia?oiai
eeano aoee aiaenooii iciaee canoieii? na?oeaai? iaaeinoaoiinoi, a o
oai?eo ae?oaiai eeano niinoa?iaaeenue iciaee iiii?ii? eiaioeoii/eiai?
iaaeinoaoiinoi: ia?iiaee/ia aeieeiaiiy caaeeoee i iineeaiiy na?oeaaeooy,
aieiai o?eie a ieaeiio aiaeaeieao eaaaiue, iaoieiai/iee o?aoie oii ia
aa?oiaoei na?oey. O anio iaoei?ioia caa?iaaany neioniaee ?eoi.

O 42 oai?eo II aoa ia?oei eeiii/iei i?iyaii ION; o 85 a aiaiiaci aoee
i?enooie noaiiea?aei?, o 31 — a?oa?iaeueia aiia?oaiciy (o 9 oai?eo 1-?,
a o 22 oai?eo — 2-? noaaei?), o 14 — eiiiainiaaiee oeoe?iaee aeiaaao
II-ai oeio.

O aeineiaeaeaiiy ia aeeth/aee oai?eo c i?ioeiieacaie aei i?iaaaeaiiy
o?iiaieioe/ii? oa?aii? oa oaeaeeiai ?icoe?aiiy ?ooiaiai ?aaeeio, aieii
iiiaae 70 ?ieia, c aaaeeeie i?iyaaie iaaeinoaoiinoi e?iaiiaiao, aaaeeeie
nenoaiieie caoai?thaaiiyie, ia/iieiaith aai ie?eiaith iaaeinoaoiinoth,
ieaioeeaith a?eoii?th aai o?iiioiiiyi ia?aaena?aeue, o?iii/ieie
ianiaoeeoi/ieie caoai?thaaiiyie eaaaiue, iieieiai/ieie caoai?thaaiiyie,
i?e iayeiniiio aoiea?aeiia?aoi/iiio cia?aaeaiii.

Aeiaaiic aino?iai II anoaiiaethaaee i?e iayaiinoi aeaio e?eoa?i?a c
oaeeo o?ueio: 1) oeiiaiai aiaiiiciiai i?enooio; 2) oeiiaeo aeey II ciii
AEA; 3) c?inoaiiy aeoeaiinoi iiiea?aeiaeueieo oa?iaioia. Anii oai?ei i?e
iinooieaiii i?iaiaeeeanue aeaeo?iea?aeiia?aoiy oa aoiea?aeiia?aoiy, ca
aeaieie yeeo anoaiiaethaaeany eieaeicaoeiy oa aeeaeia o?aaeaiiy
iiiea?aeo. O anio oai?eo aeiaaiinooaaee o?ainio?aeueiee II (ic coaoeai
Q). Ca eieaeicaoei?th o 74 oai?eo aoa II ia?aaeiuei? eieaeicaoei?, o 37
— caaeiuei-ieaeiuei? eieaeicaoei?, o 10 — aieiai? eieaeicaoei?, o 6 —
?iciianthaeaeaiee II (ia?aaeiuei-aieiaee aai caaeiuei-aieiaee).

Anio oai?eo ?aiaeiiicoaaee o o?e a?oie: I a?oia («A+NE») — 15 oai?eo,
yei io?eioaaee o?iiaieioe/io oa?aiith (no?aioieiiaca aeiaaiii 1.5 iei
iae. i?ioyaii 60 oaeeei) i anii?ei o aeici 325 ia uiaeaiii; II a?oia
(«A»)- 49 oai?eo, yei io?eioaaee anii?ei o aeici 325 ia uiaeaiii; III
a?oia (eiio?ieueia) — 63 oai?eo, yei ia io?eioaaee anii?eio i
o?iiaieioe/ii? oa?aii?. ?aooa eieoaaiiy o anio a?oiao aoei noaiaea?oiei:
aaia?ei ii 5 oen.iae. iiaeoei?ii 4 ?ace ia aeaiue i?ioyaii 5 aeia,
i?iiaiieie 20 ia 3 ?ace ia aeaiue, iio?ini?aiae 20 ia 3 ?ace ia aeaiue.

Iiney aeienee ci noaoeiiia?o ani a?oie oai?eo i?iaeiaaeoaaee i?eeiaoe
i?ecia/aia eieoaaiiy.

*a?ac 10 aeia, 20 aeia i 6 iinyoeia i?iaiaeeee iiaoi?ia ianoaaeaiiy
oai?eo. Aei 6-ai iinyoey aiae ii/aoeo caoai?thaaiiy iiia?ee 2 oai?eo c
ae?oai? a?oie (nia?oue ianoaea ?aioiai aaeiia iiney aeienee c eeiiiee) i
3 oai?eo c eiio?ieueii? a?oie (iaeei — aiae iiaoi?iiai iioa?eoo
iiiea?aea, a aeaa oai?eo — i?e ia?inoath/eo yaeuao na?oeaai?
iaaeinoaoiinoi). Aiaeiiaiaeii, /a?ac 6 iinyoeia eieueeinoue ianoaaeaieo
a ae?oaie i eiio?ieueiie a?oiao ciaioeeanue: aoei ianoaaeaii 47 oai?eo c
ae?oai? a?oie i 60 oai?eo c o?aouei? a?oie.

Onii oai?ei aiae iiiaioo iinooieaiiy a eeiiieo i?iaiaeeee
caaaeueiieeiii/ia ianoaaeaiiy, yea ia?aaeaa/aei caaaeueiee aiaeic e?iai,
caaaeueiee aiaeic na/i, aiioiii/iee aiaeic e?iai, iiiioi?oaaiiy AEA
ai?iaeiaae ia?oeo aeaio aeia caoai?thaaiiy, iiaeaeueoee uiaeaiiee
eiio?ieue AEA, ?aioaaiieiai/ia aeineiaeaeaiiy i?aaiia a?oaeii? eeioee,
eiiieaenia aoiea?aeiia?aoi/ia aeineiaeaeaiiy, oieoa?ianueea
iiiioi?oaaiiy AEA c iaoith ooi/iaiiy oa?aeoa?o ii?ooaiue ?eoio oa
i?iaiaeiinoi. Ia 10 aeaiue caoai?thaaiiy, ia?aae aeieneith (20-21
aeaiue) i /a?ac 6 iinyoeia i?e aiaenooiinoi i?ioeiieacaiue i?iaiaeeee
i?iao c oice/iei iaaaioaaeaiiyi.

Aoiea?aeiia?aoi/ia aeineiaeaeaiiy i?iaiaeeee ia aoiea?aeiia?aoi
Sigma-44 HVD (Kontron Instr., O?aioeiy) ca aeiiiiiaith iaoaii/iiai
aeao/eea 3.5 IAoe.

Aeey ioeiiee nenoiei/ii? ooieoei? eiaiai oeoii/ea (EO) aeei?enoiaoaaany
iaoiae, yeee aaco?oueny ia aecia/aiii eiioeaai-aeianoiei/iiai ia’?io ca
aeiiiiiaith iaoiaeo L. Teicholtz i oaea?iiai ia’?io, yeee aecia/a?oueny
aeiiiea?aoiea?aeiia?aoi/iei iaoiaeii i?e ?a?no?aoei? nenoiei/iiai iioieo
a ai?oi. O?aeoeith aeeeaeo (OA) io?eioaaee ye ae?aaeaia o aiaenioeao
niiaaiaeiioaiiy oaea?iiai ia’?io aei eiioeaai-aeianoiei/iiai ia’?io EO,
eiioeaai-nenoiei/iee ia’?i ae?aoiaoaaee ye ?icieoeth iiae
eiioeaai-aeianoiei/iei ia’?iii EO i oaea?iei ia’?iii.

I?iao c oice/iei iaaaioaaeaiiyi ia aaeia?aiiao?i i?iaiaeeee cae/aeii
a?aioei ia aeineiaeieoeueeiio eiii’thoa?eciaaiiio aaeia?aiiao?e/iiio
eiiieaeni AAA.10.25 Ee?anueeiai iaoeiai-aeineiaeiiai eiino?oeoi?nueeiai
ath?i «A?aiiao?» c aicoaeueiei eiio?ieai ia iiiioi?i AEA o o?ueio
aiaeaaaeaiiyo (II, V2, V5) i iiaeeeainoth ia?aaeyaeo AEA o aoaeue-yeeo
iioeo aiaeaaaeaiiyo ci oaeaeeinoth iaaeaethaaiiy 55-60 iaa?oia ia 1 oa.
Iiney caeii/aiiy i?iae caeienithaaany ia?aaeyae AEA oi?iaeiaae onueiai
oanoo c ae?oeoaaiiyi o?aaiaioia AEA o iaaii iiiaioe.

Aeei?enoiaoaaeinue nooiaiaiiaeiaia c?inoath/a aacia?a?aia
iaaaioaaeaiiy. O?eaaeinoue eiaeiiai nooiaiy noaiiaeea 3 oaeeeie;
ii/aoeiaa iaaaioaaeaiiy aoei 25 Ao, a eiaeia ianooiia caieueooaaeinue ia
25 Ao.

E?eoa?i? i?eieiaiiy i?iae ?aaeaiaiooaaeenue Iaeacii IIC Oe?a?ie ?206
aiae 30.12.1992 ?ieo «I?i caoiaee uiaei i?aaiicaoei? oa iiaeaeuaiiy
yeinoi ea?aeiieiai/ii? aeiiiiiae ianaeaiith Oe?a?ie».

Oiea?aioiinoue aei iaaaioaaeaiiy ioeiithaaee ca iieacieeaie
iiooaeiinoi, caaaeueiiai ia’?io aeeiiaii? ?iaioe, a oaeiae eieueeinoi
iaoaaiei/ieo iaeeieoeue oa iiaeaieiiio aeiaooeo.

24-aiaeeiio ?a?no?aoeith AEA caeienithaaee ia iaaiioio no?i/eo ca
aeiiiiiaith iaeii?aciaeo aeaeo?iaeia Carbo Cone (Oaaeoea?iy) i
ii?oaoeaiiai ea?aeiiiiiioi?o Holter Re?orter oi?ie ACS (NOA), yeee
aeicaiey? caienoaaoe AEA o o?ueio iiaeeoieiaaieo aiaeaaaeaiiyo V1, V3 i
V5.

Aiaeic aeiaiaiai caieno AEA caeienithaaee ca aeiiiiiaith aeaoeo?aoi?a
The Holter Re?orter, Multi Tasking Analyser 2-3 oi?? ae oi?ie (ia aaci
eiii’thoa?a IBM AO-386). Ioeiithaaeenue aeeiaiieo naaiaioo ST —
o?eaaeinoue oa /anoioo aeieeiaiiy ioaii? oa caaaeueio eieueeinoue
oeoii/eiaeo oa iaaeoeoii/eiaeo ii?ooaiue ?eoio ca aeiao oa ?o /anoioo ca
eiaeio aiaeeio.

Ioeiieo aeinoiai?iinoi aiaeiiiiinoi iieacieeia, yei yaeythoue niaith
ia?aiao?e/ii aaee/eie i?iaiaeeee c aeiiiiiaith t-oanoo: aiaeic aeeiaiiee
io?eiaieo ia?aiao?ia i?iaiaeeany c aeiiiiiaith ia?iiai t-oanoo, a
ii?iaiyiiy ia?aiao?ia o ?icieo eeiii/ieo a?oiao c aeiiiiiaith iaia?iiai
t-oanoo (?acoeueoaoe aaaaeaeeny aeinoiai?ieie i?e ? < 0.05). Ei?aeyoeieii niiaaiaeiioaiiy ae?aoiaoaaee iaoiaeii eiiieii? ?aa?ani? aeey ia?aiao?e/ieo aeaieo i iaoiaeii ?aiaiai? ei?aeyoei? Nii?iaia aeey iaia?aiao?e/ieo aeaieo. Ani ia?aooiee i?iaiaeeee ia ia?niiaeueiiio eiii'thoa?i IBM ?C ca aeiiiiiaith nenoaie oi?aaeiiiy aacaie aeaieo Fox?ro v.2.6 (MicroSoft, USA) i noaoenoe/ii? i?ia?aie STATISTICA FOR WINDOWS v.4.3 (StatSoft, USA). Ani io?eiaii aeaii iiaeaee o aeaeyaei (na?aaei? a?eoiaoe/ia + iioeaea na?aaeiueiai a?eoiaoe/iiai). ?acoeueoaoe aeanieo aeineiaeaeaiue Aiaeic aeeiaii/ieo ciii iieacieeia nenoiei/ii? ooieoei? na?oey iieacaa, ui aaea ia 10 aeiao niinoa?iaa?oueny aeinoiai?ia caieueoaiiy o?aeoei? aeeeaeo o a?oii, yea io?eioaaea o?iiaieioe/io oa?aiith i anii?ei (c 46.8+1.2% aei 52.2+0.8%, ?<0.001) (?en. 1). Aeaui iaioa oey oaiaeaioeiy aoea ae?aaeaia o a?oii, yea io?eioaaea eeoa anii?ei (c 46.2+1.3% aei 50.4+0.8%, ?<0.01). A eiio?ieueiie a?oii o?aeoeiy aeeeaeo inoioieo ciii ia caciaea. O anio a?oiao ianoaaeaieo ia 10 aeaiue eiioeaai-aeianoiei/iee ia'?i ia ciiieany, a oie /an, ye niinoa?iaaeinue aeinoiai?ia ciaioaiiy eiioeaai-nenoiei/iiai ia'?io o a?oiao, yei io?eioaaee o?iiaieioe/io oa?aiith i anii?ei (c 63.8+1.6 ie aei 54.1+1.6 ie, ?<0.01), a oaeiae o a?oii oai?eo, yei i?eeiaee eeoa anii?ei (64.8+3.5 ie aei 57.3+4.0 ie, ?<0.05). Oaeiae niinoa?iaaeinue caieueoaiiy oaea?iiai ia'?io EO o a?oiao, yei io?eioaaee o?iiaieioe/io oa?aiith i anii?ei (c 58.1+3.1 ie aei 62.9+3.1 ie, ?<0.01), a oaeiae o a?oii oai?eo, yei i?eeiaee eeoa anii?ei (c 57.6+2.5 ie aei 61.4+2.5 ie, ?<0.05). wmetafile8? ??Oe?????????? ???????yyy???????????? a?#??? ???/???????????????????????????????AAA?AUeA?¤E??ep?en. 1 Aeeiaiiea ciii o?aeoei? aeeeaeo eiaiai oeoii/ea o oai?eo iiney aino?iai iioa?eoo iiiea?aea caeaaeii aiae eieoaaiiy. Ia 20 aeaiue i /a?ac 6 iinyoeia iiney aeieeiaiiy aino?iai iioa?eoo iiiea?aea aiaeii/aeiny niiaieueiaiiy oaiio aiaeiiaeaiiy o?aeoei? aeeeaeo EO o a?oiao, yei io?eioaaee o?iiaieioe/io oa?aiith i/aai anii?ei. Iaeii/anii a oeeo a?oiao niinoa?iaaeiny niiaieueiaiiy ciii eiioeaai-aeianoiei/iiai i eiioeaai-nenoiei/iiai ia'?iia, yei ia iaee aeinoiai?ieo aiaeiiiiinoae o ii?iaiyiii ci noaiii ia 10 aeiao, oi/a aeinoiai?ii aiae?iciyeeny aiae aeoiaeieo aeaieo. I?ioa aiaeii/aeiny iie?auaiiy o?aeoei? aeeeaeo o eiio?ieueiie a?oii, yea ii/eiaei aeinoiai?ii aiae?iciyoeny aiae aeoiaeieo aeaieo eeoa /a?ac 6 iinyoeia (c 46.4+1.7% aei 50.3+2.2%, ?<0.05). Iaeiae o oeie a?oii niinoa?iaa?oueny caieueoaiiy eiioeaai-nenoiei/iiai oa eiioeaai-aeianoiei/iiai ia'?iia EO, ui iiaea naiae/eoe i?i aieueoo ae?aaeaiinoue i?ioeania ?aiiaeaethaaiiy o oai?eo, yei ia io?eioaaee o?iiaieioe/io oa?aiith oa anii?ei. Oaeei /eiii, /a?ac 6 iin. iiney aeieeiaiiy aino?iai iioa?eoo iiiea?aea ia aiaeii/a?oueny aeinoiai?ieo aiaeiiiiinoae o o?aeoei? aeeeaeo EO iiae a?oiaie oai?eo. Ioaea, oa?aiiy no?aioieiiacith oa anii?eiii aea? oaeaeeo ii?iaeicaoeith nenoiei/ii? ooieoei? iiiea?aea, cie?aia o?aeoei? aeeeaeo, aea aaea /a?ac 6 iin. oei iieacieee o anio a?oiao ii/eiathoue caeeaeoaaoeny. O?eaaeinoue ioaii? ia 1-3 aeiao o a?oii oai?eo, ui io?eioaaea no?aioieiiaco oa anii?ei, aoea iaeiaioa i noaiiaeea 36.1+8.3 oa., ui iia'ycaii c aiaeiiaeaiiyi e?iaiieeio o ei?iia?iie a?oa?i?. Aiaeic aeeiaii/ieo ciii o?eaaeinoi ioaii? iieacaa, ui ia 10 aeiao aiaeii/aeiny aeinoiai?ia ciaioaiiy o?eaaeinoi ioaii? o eiio?ieueiie a?oii (c 64.5+15.8 oa. aei 38.1+22.5 oa., ?<0.05) i o a?oii, yea io?eioaaea anii?ei (c 61.5+18.8 oa. aei 36.1+19.3 oa., ?<0.05). A a?oii, oai?i yei? io?eioaaee o?iiaieioe/io oa?aiith i anii?ei ia 10 aeiao o?eaaeinoue ioaii? aeinoiai?ii ia ciiieeany, oi/a i caeeoaeeny iaeieae/ith na?aae anio a?oi oai?eo (?en. 2). Oea iiaeia iiynieoe oaiiiaiii niiioaiii? ?aia?ooci? o oai?eo, yeei ia i?iaiaeeee o?iiaieioe/ii? oa?aii?, aai aeeeth/aiiyi c nenoaie ei?iia?iiai e?iaioieo aeieyiee noi?iiaaiiai iioa?oeo iiiea?aea. wmetafile8? ??A?????????? ???????yyy???????????? a?#??? ???/???????????????????????????????AAA?AUeA?¤E??ep?en. 2 Aeeiaiiea ciii o?eaaeinoi ioaii? o oai?eo iiney aino?iai iioa?eoo iiiea?aea caeaaeii aiae eieoaaiiy. Ia 20 aeaiue niinoa?iaaeinue iaaeinoiai?ia ciaioaiiy o?eaaeinoi ioaii? o anio a?oiao ianoaaeaieo, ui iia'ycaii c ?ooeiiei i?ecia/aiiyi iio?aoia ia ainiioaeueiiio aoaii anii oai?ei oa iiaeeeth/aiiyi eieaoa?aeueiiai e?iaiiaiao. *a?ac 6 iinyoeia aiaeii/aii c?inoaiiy o?eaaeinoi ioaii?, yea ca?a?no?iaaia o anio a?oiao, ui coiiaeaii i?iaeiaaeaiiyi i?ioeano aoa?iaaiaco. I?ioa o a?oii, yea io?eioaaea o?iiaieioe/io oa?aiith oa anii?ei i o a?oii c anii?eiii o?eaaeinoue ioaii? caieueoo?oueny iacia/ii - c 30.3+4.0 oa. aei 41.2+17.2 oa., ?>0.05 oa c 32.7+15.3 oa. aei
43.8+16.9 oa., ?>0.05 aiaeiiaiaeii, ?icieoey iaaeinoiai?ia, a oie /an ye
o eiio?ieueiie a?oii o?eaaeinoue ioaii? aeinoiai?ii c?inoa? iaeaea a
aeaa ?ace (c 33.2+17.2 oa. aei 71.1+32.6 oa., ?<0.05). Oea iiaea naiae/eoe i?i i?ioaeoi?io aeith o?eaaeiai i?eeiio anii?eio aiaeiinii oaiiia aoa?iaaiaco. Aeineiaeaeaiiy ei?aeyoei? iiae o?eaaeinoth ioaii? i iieacieeaie nenoiei/ii? ooieoei? na?oey iieacaei, ui inio? aeinoiai?iee ca'ycie na?aaeiuei? neee iiae o?eaaeinoth ioaii? i oaeeie iieacieeaie nenoiei/ii? ooieoei? na?oey, ye o?aeoeiy aeeeaeo eiaiai oeoii/ea (r=-0.45, ?<0.001, ?en. 3) oa eiioeaai-nenoiei/iee ia'?i eiaiai oeoii/ea (r=0.47, ?<0.000). Oiaoi inio? aca?iia caeaaeiinoue iiae oeeie iaiia iieacieeaie - iaioa eieueeinoue aiiciaeia ioaii? naiae/eoue i?i iaioo nooiiiue o?aaeaiiy ei?iia?iiai ?onea, ui aiaeaeaa?oueny ia ianiniie ooieoei? na?oey, yeo oa?aeoa?eco? o?aeoeiy aeeeaeo. A oie naiee /an ia ca?a?no?iaaii cia/eiiai ca'yceo o?eaaeinoi ioaii? c oaeeie iieacieeaie, ye eiioeaai-aeianoiei/iee ia'?i (r=0.29, ?=0.001) oa oaea?iee ia'?i eiaiai oeoii/ea (r=0.11, ?=0.22). wmetafile8? ??e!?? ?”??????? *???? i(?????.????????i(?????yyy????ue??yyy??????-?????u???? ???????-????ay6?)ay??? ???????uth???????en. 3 Ca'ycie iiae o?eaaeinoth ioaii? i o?aeoei?th aeeeaeo eiaiai oeoii/ea. Ianooiiee ei?aeyoeieiee aiaeic iieacaa, ui ia 10 aeaiue iiney aeieeiaiiy aino?iai iioa?eoo iiiea?aea ia inio? aeinoiai?iiai ca'yceo iiae noia?iith aeiaiaith o?eaaeinoth ioaii? ca aeaieie Oieoa?ianueeiai iiiioi?oaaiiy AEA i ii?iaiaei ?iaiai iaaaioaaeaiiy aeinyaiooei i?e aeeiiaiii i?iae c aeiciaaiei oice/iei iaaaioaaeaiiyi (r=-0.12, p>0.05).
Oea iiynith?oueny oei, ui iaeiei c e?eoa?i?a i?eieiaiiy aaeia?aiiao?i?
aoei aeinyaiaiiy ?iaiy iaaaioaaeaiiy 75 Ao aai *NN 120/oa. iacaeaaeii
aiae i?iyaia ioaii? ia AEA. I?ioa aaea ia 20 aeaiue, eiee aaeia?aiiao?iy
i?iaiaeeeanue aei aeinyaiaiiy noaiaeneiaeueii? *NN aai i?iyaia ioaii?,
ca?a?no?iaaiee aeinoiai?iee neeueiee i?yiee ca’ycie iiae o?eaaeinoth
ioaii? i ii?iaiaei ?iaiai iaaaioaaeaiiy (r=-0.67, p<0.001) (?en. 4). Oeae ca'ycie aeyaeany neeueiei i aeinoiai?iei i /a?ac 6 iinyoeia. wmetafile8? ??®#?? ?”??????? *???? i(?????.????????i(?????yyy????ue??yyy??????-?????u???? ???????-????ay6?)ay??? ???????uth???????en. 4 Ca'ycie iiae o?eaaeinoth ioaii? i ii?iaiaei ?iaiai iaaaioaaeaiiy i?e aaeia?aiiao?i?. I?iaaaeaii ia 10 aeiao i?iae c aeiciaaiei oice/iei iaaaioaaeaiiyi iieacaee, ui ii/aoeiaa oiea?aioiinoue aoea aeuith o oai?eo, yei io?eiaee o?iiaieioe/io oa?aiith oa anii?ei - 74.0+1.6 Ao ii?iaiyii c a?oiith, yea io?eioaaea eeoa anii?ei (68.7+4.6 Ao) oa eiio?ieueiith a?oiith (66.7+4.2 Ao). Aiaenioie coieiee i?ia c i?eaiaeo ?icaeoeo ioaii? aoa iacia/iei i i?aeoe/ii iaeiaeiaei o anio a?oiao. Ia 20 aeiao niinoa?iaa?oueny aeinoiai?ia caieueoaiiy ii?iaiaiai iaaaioaaeaiiy o anio a?oiao ianoaaeaieo, i?ioa iaeaieueoee i?e?ino ca?a?no?iaaiee o a?oii, yea io?eioaaea o?iiaieioe/io oa?aiith i anii?ei - aei 125.8+4.2 Ao (?<0.001) (?en. 5.). Aeaui iaioa oey oaiaeaioeiy aoea ae?aaeaia o a?oii, yea io?eioaaea eeoa anii?ei - aei 107.2+3.2 Ao (?<0.001) i a eiio?ieueiie a?oii (aei 95.4+4.7 Ao, ?<0.01). *a?ac 6 iinyoeia iieacieee oiea?aioiinoi aei oice/iiai iaaaioaaeaiiy i ei?iia?iiai ?aca?ao i?iaeiaaeoaaee caieueooaaoenue o anio a?oiao ianoaaeaieo, i?ioa niinoa?iaaeinue cieaeaiiy i?e?inoo o a?oii, yea io?eioaaea o?iiaieioe/io oa?aiith i anii?ei, a oie /an, ye o a?oii oai?eo, yei io?eioaaee anii?ei i a eiio?ieueiie a?oii oaiie i?e?inoo caeeoeeeny ia iiia?aaeiueiio ?iaii, i?e/iio o eiio?ieueiie a?oii niinoa?iaaany iaeaeuee aiaenioie coieiie i?ia o ca'yceo c ?icaeoeii ioaii?. Oaeei /eiii, /a?ac 6 iinyoeia aiaeaoaa?oueny caeeaeaiiy iieacieeia oiea?aioiinoi aei oice/iiai iaaaioaaeaiiy i ei?iia?iiai ?aca?ao o a?oiao oai?eo, ui, eiiai?ii, oaeiae iia'ycaii c i?iaeiaaeaiiyi i?ioeano aoa?iaaiaco. wmetafile8? ??=?????????? ???????yyy???????????? a?#??? ???/???????????????????????????????AAA?AUeA?¤E??ep?en. 5 Aeeiaiiea ciii ii?iaiaiai iaaaioaaeaiiy o oai?eo iiney aino?iai iioa?eoo iiiea?aea caeaaeii aiae eieoaaiiy. I?ioyaii 6 iinyoeia ie i?iaiaeeee ?a?no?aoeith eeiii/iiai ia?aaiao ION o aeineiaeaeoaaieo oai?eo. ?a?no?oaaeeny oaei aeiaaeee ye ?aioiaa nia?oue, iiyaa eeiii/ieo i?iyaia na?oeaai? iaaeinoaoiinoi, iiaoi?ia ainiioaeicaoeiy o ca'yceo c aino?ei ei?iia?iei neiae?iiii oa iayaiinoue aeinoaiaiieo ioaii/ieo aiiciaeia i?e iiaoi?iiio aeiaiaiio iiiioi?oaaiii AEA. Oei “eiioeaai oi/ee” aoee niianoaaeaii c io?eiaieie ?acoeueoaoaie iino?oiaioaeueieo aeineiaeaeaiue. ?acoeueoaoe ii?iaiyeueiiai aiaeico oaeoi?ia, ui aecia/athoue i?iaiic aeieeiaiiy eiioeaaeo oi/ie aeineiaeaeaiiy iiaeaii o oaaeeoei 1. Ii?iaiyeueiee aiaeic naiae/eoue, ui iaeaaaeeeaioei oaeoi?ii, yeee aecia/a? iaeaeeae/ee i?iaiic i aeieeiaiiy anio eiioeaaeo oi/ie ? o?aeoeiy aeeeaeo eiaiai oeoii/ea i cia/aiiy eiioeaai-aeianoiei/iiai ia'?io a 1-o aeiao caoai?thaaiiy. Oeae ?acoeueoao iiaeoaa?aeaeo?oueny ?acoeueoaoaie iioeo aeineiaeaeaiue [M.Pfeffer, 1990, R.N.Stevenson, 1994]. Aaaeeeaeie ? oaeiae ?acoeueoaoe i?iaiicoaaiiy aiaeaeaeaii? eaoaeueiinoi ia iniiai aaaaoioaeoi?iiai aiaeico aeaieo eeiiiei-iino?oiaioaeueiiai aeineiaeaeaiiy. Iaeaieueoo i?iaiinoe/io cia/eiinoue ia? aaee/eia oiea?aioiinoi aei oice/iiai iaaaioaaeaiiy, ui iiaeoaa?aeaeothoue ?acoeueoaoe iioeo aeineiaeaeaiue [A.I.Ooiaeia, 1994, R.N.Stevenson, 1994], a oaeiae aaee/eia iiaeaieiiai aeiaooeo, aecia/aii ia 10 aeiao c /ano ?icaeoeo II. E?ii oiai, oeiiiieie i?aaeeeoi?aie o i?iaiicoaaiii iiaoi?ieo ainiioaeicaoeie aeyaeeany iayaiinoue ioaii? i?e Oieoa?ianueeiio iiiioi?oaaiii o aino?iio ia?iiaei iioa?eoo iiiea?aea. Eieoaaeueia oaeoeea aaaeaiiy oai?eo, yea aoea aiaeia?aaeaia a?oiaie oai?eo, aeyaeeany aaaeeeaei i?aaeeeoi?ii aeieeiaiiy na?oeaai? iaaeinoaoiinoi, iiaoi?ieo ainiioaeicaoeie i aeieeiaiiy ioaii? i?ioyaii 6 iinyoeia iiney iioa?eoo iiiea?aea. Oaaeeoey 1 Ii??aiyeueiee aiae?c i?iaiinoe/ieo oaeoi??a e?ioeaaeo oi/ie aeine?aeaeaiiy (I±m) IieacieeNI (n=18/122)?aioiaa nia?oue (n=5/127)Iiaoi?ia aini?oae?caoe?y (n=26/122)?oai?y i?e OI (n=22/122)A?oie oai?eo (%)*10.5% (NE+A) 12.2% (A) 15.8% (Eiio.)*0.0% (NE+A) 4.0% (A) 4.8% (Eiio.)15.8% (NE+A) 18.4% (A) 22.0% (Eiio.)*10.5% (NE+A) 16.3% (A) 20.6% (Eiio.)EAeI EO (ie)169.2±7.9* 122.3±5.6148.2±7.3* 123.2±5.7156.2±6.9* 121.2±5.3132.1±6.3 122.3±5.6ENI EO (ie)111.2±4.8* 65.4±3.674.2±5.3 66.3±3.7118.2±6.3* 64.9±3.575.5±5.2 65.9±3.6OA EO (%) 29.4±1.5* 45.5±1.732.4±1.8* 46.3±1.733.6±1.6* 44.4±1.842.5±1.8 45.2±1.8Oeoi.I? 328.1±118.6 278.6±105.5378.3±95.6 283.3±112.5343.1±134.6 265.1±98.5312.1±123.6 267.6±115.3Iaaeo.I? 154.6±74.5 122.5±71.2165.2±77.4 111.5±76.3145.5±75.4 126.6±73.1159.3±74.5 135.8±74.2?oai?y, oa54.2±14.3 43.5±12.558.3±17.3 42.1±10.569.2±11.3* 40.3±10.574.2±12.3* 42.5±10.5Iaaaioaaeaiiy Ao68.4±5.4* 75.4±3.259.3±5.2* 75.7±3.269.5±5.5* 75.8±3.167.1±5.2* 76.1±3.1Ii?iaiaa *NN91.3±3.5 108.6±2.593.7±3.8 103.5±2.892.7±3.6 111.3±2.994.4±3.2 107.2±2.6Iiaea?eiee aeiaooie105.2±6.5* 145.8±5.2107.1±6.6* 146.9±5.3104.1±6.4* 144.9±5.3102.3±6.4* 142.4±5.1II 4.2±0.3* 4.9±0.34.4±0.3 4.7±0.34.1±0.3* 4.8±0.34.3±0.3 4.6±0.3I?eiioee: 1. O /enaeueieeo iiaeaii cia/aiiy iieacieea o oai?eo, o yeeo aeieeea eiioeaaa oi/ea aeineiaeaeaiiy, a o ciaiaiieeo iiaeaii cia/aiiy iieacieea o oai?eo, o yeeo eiioeaaa oi/ea ia aeieeea. 2. * - aiaeiiiiinoue aeinoiai?ia c ?<0.05 AENIIAEE 1. ?aii? - ia 10 oa 20 aeiao aino?iai iioa?eoo iiiea?aea, i?iaaaeaiiy oanoo c iaaaioaaeaiiyi caiaeii cai?iiiiiaaii? iaoiaeeee ? aacia/iei, eiai ?acoeueoaoe iiaeooue aooe aeei?enoaii a yeinoi e?eoa?i?a aiaeai?o oai?eo aeey ianooiii? i?enei?aii? ?aaaieioaoei?, a oaeiae ye i?iaiinoe/ii oaeoi?e iiaeaeueoiai ia?aaiao ION. 2. O aieueoinoi oai?eo, yei ia aeinyaee iiae /an aeeiiaiiy ia 10 aeiao no?an-oanoo ?iaiy iaaaioaaeaiiy 75 Ao aai yei iaee i?e?ino *NN aieueoa 120 oae/oa aei aeinyaiaiiy aeaiiai aoaio iaaaioaaeaiiy, iiaeaeueoee ia?aaia ION aeinoiai?ii /anoioa oneeaaeithaaany ?icaeoeii ?aioiai? nia?oi, na?oeaai? iaaeinoaoiinoi, aieueo o?eaaeeie aiiciaeaie ioaii? i?e iiaoi?iiio aeiaiaiio iiiioi?oaaiii AEA. Oaeo ae i?iaiinoe/io cia/eiinoue aaea a ia?oo aeiao caoai?thaaiiy iaee iieacieee eiioeaai-aeianoiei/iiai ia'?io oa o?aeoeiy aeeeaeo. 3. Canoinoaaiiy o?iiaieioe/ii? oa?aii? i anii?eio i?ecaiaeeoue aei caieueoaiiy /anoioe ii?ooaiue ?eoio a ?aiiueiio ia?iiaei caoai?thaaiiy, a c 10 aeiae aiaeii/a?oueny aeinoiai?ia ciaioaiiy /anoioe ii?ooaiue ?eoio ii?iaiyii c oai?eie, yei ia io?eioaaee o?iiaieioe/ii? oa?aii? i anii?eio. 4. O?iiaieioe/ia oa?aiiy i anii?ei iacaeaaeii iaeei aiae iaeiiai i?enei?ththoue aiaeiiaeaiiy nenoiei/ii? ooieoei? eiaiai oeoii/ea o oai?eo ia aino?ee iioa?eo iiiea?aea. Iaeaieueoee i?e?ino o?aeoei? aeeeaeo i?e eieoaaiii anii?eiii i o?iiaieioe/ieie i?aia?aoaie iayaiee o oai?eo c iecueeeie aeoiaeieie iieacieeaie nenoiei/ii? ooieoei? na?oey. O oai?eo, ia eieiaaieo anii?eiii i o?iiaieioeeaie, i?ioiaeeoue aieueo niiaieueiaia aiaeiiaeaiiy iieacieeia nenoiei/ii? ooieoei? eiaiai oeoii/ea. *a?ac 6 iinyoeia iiney caoai?thaaiiy iieacieee nenoiei/ii? ooieoei? eiaiai oeoii/ea noathoue iaeaioe/ieie a iaio a?oiao. 5. Canoinoaaiiy o?iiaieioe/ii? oa?aii? i anii?eio ni?ey? ciaioaiith i?iyaia ioaii? ca aeaieie Oieoa?ianueeiai iiiioi?oaaiiy aaea a ?aiiueiio ia?iiaei caoai?thaaiiy. Oey caeaaeiinoue caa?iaa?oueny i?ioyaii 6 iinyoeia. 6. Oai?i aino?ei iioa?eoii iiiea?aea iiney canoinoaaiiy no?aioieiiace oa anii?eio, i, a iaioie ii?i, iiney canoinoaaiiy eeoa anii?eio, e?aua ia?aiinyoue oice/ii iaaaioaaeaiiy ai?iaeiaae onio aoaiia niinoa?aaeaiiy. 7. Io?eiaii aeaii aeicaieythoue c?iaeoe aeniiaie, ui canoinoaaiiy o?iiaieioeeia oa aioeaa?aaaioia ye o ii?aeiaiii, oae i ie?aii - a aino?iio ia?iiaei II aeicaiey? i?iaiaeeoe i?enei?aio oice/io ?aaaieioaoeith i nei?ioeoe oa?iiie ia?aaoaaiiy oai?eo o noaoeiiia?i. I?AEOE*I? ?AEIIAIAeAOe?? 1. O?iiaieioe/ia oa?aiiy i anii?ei i?e aiaenooiinoi i?ioeiieacia iiaeiii i?ecia/aoeny anii oai?ei ia aino?ee iioa?eo iiiea?aea yeiiiaa ?aiioa. ?o canoinoaaiiy aeicaiey? i?enei?eoe aiaeiiaeaiiy nenoiei/ii? ooieoei? eiaiai oeoii/ea, cieceoe eiiai?iinoue aeieeiaiiy iineyiioa?eoii? noaiiea?aei? i ii?ooaiue ?eoio. 2. Oai?i ia aino?ee iioa?eo iiiea?aea, o yeeo aoea i?iaaaeaia o?iiaieioe/ia oa?aiiy i canoiniaoaaany anii?ei, iiney i?iaaaeaiiy ?aiiuei? i?iae c aeiciaaiei oice/iei iaaaioaaeaiiyi, iiaeooue i?ioiaeeoe i?enei?aio i?ia?aio ?aaaieioaoei?. 3. Oai?i, yei iiae /an oanoo c oice/iei iaaaioaaeaiiyi ia aeeiiaee iaaaioaaeaiiy o 75 Ao /e ia?aaeueee *NN 120 oae/oa i?e aeacaiiio iaaaioaaeaiii, iathoue iiaeaeuaiee ?ecee aeieeiaiiy oaeeo oneeaaeiaiue ye ?aioiaa nia?oue, na?oeaaa iaaeinoaoiinoue oa iiaoi?ii ei?iia?ii aoaee, ui iio?aaothoue ainiioaeicaoei?. NIENIE IIOAEIEIAAIEO I?AOeUe CA OAIITH AeENA?OAOeI? 1. *oao/ia I.I. Aieea anii?eio ia nei?ioeeao caeaoiinoue eiaiai oeoii/ea o oai?eo, yei ia?aianee iioa?eo iiiea?aea// Oe?.ea??ie.aeo?iae. - 1997. - ? 1. - N. 25 - 27. 2. Aecye A.A., Aai?ia E.TH., Aieuiaoe A.ss, Oaaeioeia E.I., Ai?iuoe A.A., O?eoiiiaa I.I., Aaeea? A.O., Aaeeia A.TH., Ieoaeue/aiei I.E., Aia?ia A.A., E?eei I.E., ?ooeaiei N.I., Aiiniaa A.I., I?oaeeee E.A., Eoaeeae A.Ae., Naaeei A.A., Iaoyaeaiei A.C., No?eaaiiaa I.A., Ieaiiaa I.I., Eaioei I.A., Aa?aaaiiae/ I.I., Oaeiee A.O., Iaaeee N.N., *a?eaaneee A.TH., sseiaeia E.ss., *oao/iay E.E., *oao/iue A.I., Iaeay E.O., Eiieoea I.I., Ca?ea/aoeeay E.O., Eauaiei A.A., Aeueoi ss.A., A?eoeia A.E. Ia?aue iiuo i?eiaiaiey oeaiaaiai aeoeaaoi?a ieacieiiaaia i?e eioa?eoa ieiea?aea a Oea?eia: aeaiiua iiiaioeaio?iaiai enneaaeiaaiey// Oe?.ea??ie.aeo?iae. - 1997. - ? 3. - N. 51 - 55. 3. Iaaethe A.I., AEa?iiia I.E., *oao/iee A.I., Iaaiia TH.A., *oao/ia I.I. Iiaee iaoiae aoiea?aeiia?aoi/ii? ioeiiee o?aeoei? aeeeaeo oa iaa?oiooaaiiy canoinoaaiiy eaioii?eeo o oai?eo c aino?ei iioa?eoii iiiea?aea // Oe?.ea??ie.aeo?iae. - 1997. - ? 4. - N. 8 - 10. 4. *oao/ia I.I. Aieea aoeaoeenaeioeeeiai? eeneioe oa no?aioieiiace ia aiaeiiaeaiiy nenoiei/ii? ooieoei? na?oey o oai?eo iiney iioa?eoo iiiea?aea// Eiea?nueea ni?aaa. - 1997. - ? 6. - N. 48 - 52. 5. *oao/ia I.I. Iinoea o?iiaieioe/ii? oa?aii? o eieoaaiii oai?eo c aino?ei iioa?eoii iiiea?aea// I?aeoe/ia iaaeeoeeia. - 1997. - ? 7-8. - N. 55 - 60. 6. *oao/ia I.I. Aieea oa?aii? anii?eiii oa no?aioieiiacith ia aeeiaiieo ii?ooaiue ?eoio na?oey o oai?eo c iioa?eoii iiiea?aea// Oe?.ea??ie.aeo?iae. - 1998. - ? 2. - N. 11 - 13. 7. *oao/ia I., Aioiiaiei I. ?aiiy ?aaaieioaoeiy oai?eo ic aino?ei iioa?eoii iiiea?aeo// Iaoa?iaee Ia?oi? iaoe.-i?aeo. eiio. “Iaoeiiiaeueia no?aoiaa iaaee/ia caaacia/aiiy Oe?a?ie” - Eueaia. - 1995.- N. 70 - 71. 8. *oao/ia I.I. Ooieoeiiiaeueiee noai eiaiai oeoii/ea oa iieacieee aaiiaeeiaiiee o oai?eo, yei ia?aianee iioa?eo iiiea?aea, iiae aieeaii oa?aii? aioeeiaaoeyioaie oa aioeaa?aaaioaie// Iaoa?iaee Ieaioio oe?. iaoe. oiaa?. ea?aeiie. – Aiiieoey. - 1995. - N. 13 - 14. 9. Aioiiaiei E.I, *oao/ia I.I. ?aiiy aaeia?aiiao?iy o oai?eo ia iioa?eo iiiea?aea// Iaoa?iaee Ieaioio oe?. iaoe. oiaa?. ea?aeiie. – Aiiieoey. - 1995. - N. 3. 10. *oao/ia I.I. Aieea anii?eio ia ii?ooaiiy ?eoio oa ioaiith o oai?eo c iioa?eoii iiiea?aea// Iaoa?iaee V eiia?ano ea?aeiieiaia Oe?a?ie. – Ee?a. – 1997. - N. 71. 11. *oao/ia I.I. Aoaeoeaiinoue i?enei?aii? ?aaaieioaoei? oai?eo ia aino?ee iioa?eo iiiea?aea// Iaoa?iaee 2-i? iaoe.-i?aeo. eiio. "Nenoaia nioeiaeueii-no?aoiai? iaaee/ii? iiiee a Oe?a?ii" - Eueaia. - 1997.- N. 93 - 94. 12. Pawlyk S.S., Bordiuzenko I.I., Sterniuk A.M., Czubuczna I.I Komputerowe oprogramovanie monitorovania pacjentow z zawalem miesnia sercowego // Kardiol. Polska (60 Conf. Naukowa PTK. - Gdynia, Polska, 16 maja, 1997.) - T. XLVI, Supl. II. - P 48. - S. II-52. 13. Chubuchna I. Predictive value of heart rate variability for postinfarctin ventricular remodelling in patients with ejectin fraction > 40% // Heart Fealure` 97. — Cologne, Germany, May 24-27, 1997. — P
186. — P. 49.

AIIOAOe?ss

*oao/ia I.I. Aieea oa?aii? anii?eiii oa no?aioieiiacith ia aiaeiiaeaiiy
nenoiei/ii? ooieoei? na?oey, aeeiaiieo ii?ooaiue na?oeaaiai ?eoio oa
ioaii? o oai?eo, ui i?ioiaeeee i?enei?aio i?ia?aio ?aaaieioaoei? iiney
ia?aianaiiai iioa?eoo iiiea?aea. — ?oeiien.

Aeena?oaoeiy ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe
ca niaoeiaeueiinoth 14.01.11 — ea?aeiieiaiy. Oe?a?inueeee
iaoeiai-aeineiaeiee iinoeooo ii. aeaae. I.Ae.No?aaeanea IIC Oe?a?ie,
Ee?a, 1999 ?.

I?iaaaeaii aeineiaeaeaiiy i?enay/aii aea/aiith aioo?ioiueina?oeaai?
aaiiaeeiaiiee, ?iaith ei?iia?iiai ?aca?aa oa oiea?aioiinoi aei oice/iiai
iaaaioaaeaiiy o oai?eo c AII iiney o?iiaieioe/ii? oa aioeaa?aaaioii?
oa?aii?. Anoaiiaeaii, ui no?aioieiiaca oa anii?ei iacaeaaeii iaeei aiae
iaeiiai i?enei?ththoue aiaeiiaeaiiy nenoiei/ii? ooieoei? eiaiai
oeoii/ea, a ?o ii?aeiaia canoinoaaiiy ni?ey? ciaioaiith i?iyaia ioaii?
ye a ?aiiueiio ia?iiaei caoai?thaaiiy, oae i ai?iaeiaae 6 iinyoeia
niinoa?aaeaiiy. Aeaia eieoaaiiy aeicaiey? aacia/ii i?iaiaeeoe i?enei?aio
i?ia?aio oice/ii? ?aaaieioaoei? oai?ei c AII.

Eeth/iai neiaa: iioa?eo iiiea?aea, eieoaaiiy, ?aaaieioaoeiy,
aoiea?aeiia?aoiy, Oieoa?ianueea iiiioi?oaaiiy, aaeia?aiiao?iy.

ANNOTATION

Chubuchna I.I. Influence of aspirin and streptokinase therapy on
restoring of systolic function of heart, changes of violations of a
cordial rhythm and ischemia at the patients, which passed the
accelerated program of rehabilitation after transferred of the
myocardium infarction. — Manuscript.

Thesis on competition of a scientific degree of the candidate of
medical sciences on a speciality 14.01.11 — Cardiology. The
M.D.Strazhesko Ukrainian research institute of cardiology by Ukraine
Health Ministry, Kiev, 1999.

The conducted researches are devoted to study the intercardiac
hemodynamics, level of a coronary reserve and tolerance to a physical
load at the patients with AMI of the ambassador trombolytic and
antyagregation therapy. Is established, that the trombolytic therapy and
aspirin is independent from each other accelerate restoring of systolic
function of left ventricular, and their sharing promotes a diminution of
manifestation ischemia both in early period of disease, and on stretch 6
months of observation. The given treatment allows safely to conduct the
accelerated program of physical rehabilitation by the patient AMI.

Key words: miocardial infarction, treatment, rehabilitation,
echocardiography, Holter’s monitoring, exercise testing.

AIIIOAOeEss

*oao/iay E.E. Aeeyiea oa?aiee anie?eiii e no?aioieeiacie ia
ainnoaiiaeaiea nenoiee/aneie ooieoeee na?aeoea, aeeiaieeo ia?ooaiee
na?aea/iiai ?eoia e eoaiee o aieueiuo, eioi?ua i?ioiaeeee onei?aiioth
i?ia?aiio ?aaaeeeoaoeee iinea ia?aianaiiiai eioa?eoa ieiea?aea. —
?oeiienue.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo
iaoe ii niaoeeaeueiinoe 14.01.11 — ea?aeeieiaey. Oe?aeineee
iao/ii-enneaaeiaaoaeueneee einoeooo ea?aeeieiaee ei. I.Ae.No?aaeanei ICI
Oe?aeiu, Eeaa, 1999 a.

I?iaaaeaiiua enneaaeiaaiey iinayuaiu eco/aieth aioo?ena?aea/iie
aaiiaeeiaieee, o?iaith ei?iia?iiai ?aca?aa e oiea?aioiinoe e oece/aneie
iaa?ocea o aieueiuo n ino?ui eioa?eoii ieiea?aea iinea o?iiaieeoe/aneie
e aioeaa?aaaioiie oa?aiee i?e i?iaaaeaiee onei?aiiie i?ia?aiiu
oece/aneie ?aaaeeeoaoeee.

Onoaiiaeaii oanioth ei??aeyoeeiiioth naycue iaaeaeo noiia?iie
aeeeoaeueiinoueth eoaiee i?e nooi/iii Oieoa?ianeii iiieoi?e?iaaiee,
o?aeoeeae aua?ina e o?iaiai auiieiaiiie ?aaiou a ino?ii ia?eiaea
eioa?eoa ieiea?aea. O?iiaieeoe/aneay oa?aiey e anie?ei iacaaeneii ae?oa
io ae?oaa onei?ytho ainnoaiiaeaiea nenoiee/aneie ooieoeee eaaiai
aeaeoaei/ea. Iaeaieueoee i?e?ino o?aeoeee aua?ina iaaethaeaaony o
aieueiuo n ieceeie enoiaeiuie iieacaoaeyie nenoiee/aneie ooieoeee
na?aeoea. O aieueiuo, iaea/aiiuo anie?eiii e oiiaieeoeeaie, i?ienoiaeeo
aieaa iaaeeaiiia ainnoaiiaeaiea yoeo iieacaoaeae. Nionoy 6 ianyoeaa io
ia/aea caaieaaaiey iieacaoaee nenoiee/aneie ooieoeee eaaiai aeaeoaei/ea
noaiiayony i?aeoe/anee iaeeiaeiauie ai anao enneaaeiaaiuo a?oiiao. A oi
aea a?aiy iieacaoaeue o?aeoeee aua?ina eaaiai aeaeoaei/ea e cia/aiea
eiia/ii-aeeanoiee/aneiai iauaia a ia?aua nooee caaieaaaiey yaeythony
aaaeiaeoeie i?iaiinoe/aneeie iieacaoaeyie aicieeiiaaiey aiacaiiie
ei?iia?iie nia?oe, na?aea/iie iaaeinoaoi/iinoe e iiaoi?iuo ei?iia?iuo
aoae.

Eniieueciaaiea no?aioieeiacu e anie?eia niinianoaoao oaaee/aieth /anoiou
ia?ooaiee ?eoia a ?aiiai ia?eiaea caaieaaaiey, ii n 10 nooie aeinoiaa?ii
oiaiueoaaony /anoioa a?eoiee a n?aaiaiee n a?oiiie aieueiuo, ia
iieo/aaoeo oeacaiiiai ea/aiey.

Onoaiiaeaii, /oi niaianoiia eniieueciaaiea anie?eia e no?aioieeiacu
niinianoaoao oiaiueoaieth i?iyaeaiey eoaiee i?e nooi/iii iiieoi?e?iaaiee
YEA eae a ?aiiai ia?eiaea eioa?eoa ieiea?aea, oae e nionoy 6 ianyoeaa io
iiiaioa caaieaaaiey.

I?aaeeiaeaii aaciianiia ?aiiaa iaa?oci/iia oanoe?iaaiea iinea ino?iai
eioa?eoa ieiea?aea, ?acoeueoaou eioi?iai neoaeao i?iaiinoe/aneei
oaeoi?ii aeaeueiaeoaai oa/aiey eoaie/aneie aieacie na?aeoea.
Onoaiiaeaii, a /anoiinoe, /oi o aieueiuo, ia aeinoeaoeo ia 10 nooee
caaieaaaiey iaa?ocee 75 Ao i?e no?ann-oanoa eee eiaaoeo i?e?ino *NN auoa
120 oae/iei aei aeinoeaeaiey aeaiiie iaa?ocee, aeaeueiaeoaa oa/aiea EAN
aeinoiaa?ii /aua ineiaeiyeinue ?acaeoeai aiacaiiie nia?oe, na?aea/iie
iaaeinoaoi/iinoe e aeeeoaeueiuie yieciaeaie eoaiee i?e i?iaaaeaiee
iiaoi?iiai nooi/iiai Oieoa?ianeiai iiieoi?e?iaaiey. ?aiiee iaa?oci/iue
oano iicaieyao oaeaea iauaeoeaii ioia?aoue aieueiuo aeey i?iaaaeaiey
onei?aiiie oece/aneie ?aaaeeeoaoeee, a i?iaaaeaiea onei?aiiie i?ia?aiiu
oece/aneie ?aaaueeoaoeee o aieueiuo n eniieueciaaiea o?iiaieeoeeia e
aioeaa?aaaioia a ino?ii ia?eiaea eioa?eoa ieiea?aea iicaieyao nie?aoeoue
n?ie eo i?aauaaiey a noaoeeiia?a.

Eeth/aaua neiaa: eioa?eo ieiea?aea, ea/aiea, ?aaaeeeoaoeey,
yoiea?aeeia?aoey, Oieoa?ianeia iiieoi?e?iaaiea, aaeiy?aiiao?ey.

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