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IAOeIIIAEUeIA AEAAeAIIss IAOE OE?A?IE

IINOEOOO OICIIEIAI? ii.I.I. AIAIIIEUeOess

CAAAAeAss OAOssIA EAIIOI?AIA

OAeE 616-091-001.36-008.61

Aieea iiiieo oa aeueoa-oieioa?ieo i?e

niieueiiio canoinoaaiii ia i?ioeane

ia?ieneaeaoei? eiiiaeia oa aiino oeeeei/ieo ioeeaioeaeia o na?oei,
ia/iioei oa e?iai i?e neiae?iii o?eaaeiai ?ic/aaethaaiiy a aenia?eiaioi

14.03.04 – iaoieiai/ia oiciieiaiy

Aaoi?aoa?ao aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaith

eaiaeeaeaoa aiieiai/ieo iaoe

Ee?a – 1999

Aeena?oaoei?th ? ?oeiien.

?iaioa aeeiiaia o Aeiiaoeueeiio aea?aeaaiiio iaaee/iiio oiiaa?neoaoi
ii.I.Ai?ueeiai

Iaoeiaee ea?iaiee: /eai-ei?aniiiaeaio AII Oe?a?ie, aeieoi?
iaaee/ieo iaoe,

i?ioani? ?euenueeee
Aieoi? Ieeieaeiae/, caaiaeoaa/ eaoaae?e iaoieiai/ii? oiciieiai?
Aeiiaoeueeiai aea?aeaaiiai iaaee/iiai oiiaa?neoaoo ii. I.Ai?ueeiai

Ioioeieii iiiiaioe:

Aeieoi? aiieiai/ieo iaoe, i?ioani? AEaeiei Ethaia Iaaiiaia,
Oe?a?inueea Aeaaeaiiy

aea?aeaaiiai oi?aaeiiiy i?e I?aceaeaioiai Oe?a?ie, eaoaae?a aaeaieiai?;

Aeieoi? iaaee/ieo iaoe, i?ioani? Na?aaeaiei Ieoaeei Ieoaeeiae/, Iinoeooo
oiciieiai? ii. I.I.Aiaiiieueoey IAI Oe?a?ie, caaiaeoaa/ aiaeaeieii ii
aea/aith aiiiene/ieo

noaiia;

I?iaiaeia onoaiiaa: Iinoeooo aiaeie?eiieiai? i iaiiio ?a/iaei ii.
A.I.Eiiina?aiea

AII Oe?a?ie

Caoeno aiaeaoaeaoueny ” 16 ” aa?aciy 1999 ?. i 14-00 aiae. ia
caniaeaiii niaoeiaeiciaaii? a/aii? ?aaee Ae-26.198.01. Iinoeoooo
oiciieiai? ii. I.I. Aiaiiieueoey IAI Oe?a?ie(i.Ee?a, aoe. Aiaiiieueoey,
4).

C aeena?oaoei?th iiaeia iciaeiieoenue o aiaeiioaoei Iinoeoooo oiciieiai?
ii.I.I.Aiaiiieueoey IAI Oe?a?ie ca aae?anith: i.Ee?a, aoe.
Aiaiiieueoey,4.

Aaoi?aoa?ao ?icineaiee ” 17 ” ethoiai 1999 ?.

A/aiee nae?aoa?

niaoeiaeiciaaii? a/aii? ?aaee,

aeieoi? aiieiai/ieo iaoe Ni?ieiia-Ia?iia C.I.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue i?iaeaie.

Ui?ieo niinoa?iaa?oueny c?inoaiiy ?iaith o?aaiaoecia, iniaeeai
iia’ycaiiai c ae?iaieoeoaii, o?ainii?oii oa noeoieieie eeoaie. Ca
aaniethoiith aaee/eiith nia?oiinoi o?aaiaoeci caeia? o?ao? iinoea a
naioi iiney na?oeaai-noaeeiieo oa iieieiai/ieo caoai?thaaiue oa ia?oa
iinoea na?aae ethaeae aei 45 ?ieia (I?ioeaiei A.A. oa ni?aaao., 1988).

Neiae?ii o?eaaeiai ?ic/aaethaaiiy (NO?) iaeaaeeoue aei /enea oyaeeeo
oi?i o?aaie. O aoaieueiie i?iieneiainoi o?aaiaoeci o 4 ?ace aeua, iiae a
iioeo aaeocyo ae?iaieoeoaa (Ii?aiao?a E.A. oa niiaaao., 1987).Eieoaaiiy
NO? ?ic?iaeaii iaaeinoaoiuei, oiio iaiaoiaeia aeaoaeueia aea/aiiy
iaoiaaiaco iaoaaieicio eeioei, ?iei i?ioeania ia?aeeniiai ieeneaiiy
eiiiaeia (IIE), aeoeaiinoi aioeieneaeaioii? nenoaie (AIN). Ei?aeoeiy
oeeo ii?ooaiue yaey? niaith neeaaeio i?iaeaio, oiio ui ieoaiiy, yei
oi?eathoueny ciii o aiiiaia?aiao oieiai? eeioeie, aeiaaathoue ooi/iaiiy
(A?thnia I.A.oa niiaaao., 1992).

Aiaeiii, ui iaiiii?ia aeoeaaoeiy i?ioeania IIE o aeayeeo i?aaiao i?e NO?
aaaea aei iaia?aiiaeano?oeoeaieo i?ioeania eeioei, aeoiaeo
eiciniiaeueieo oa?iaioia, yei caieueoothoue i?ioeane aeano?oeoei? o
eeioeii (A?thnia I.A. oa niiaaao., 1992). Oea iiaea aooe i?e/eiith
aeieeiaiiy iaoaaiei/ieo ii?ooaiue. Aioeieneaeaioia nenoaia noaaieico?
i?ioeane IIE. I?e iaaeinoaoiinoi aiiaaiieo aioeieneaeaioia c iaoith
ei?aeoei? ii?ooaiue i?ioeania IIE canoiniaothoue neioaoe/ii ooo/ii, ye,
iai?eeeaae, iiiie (Iaiueeianueea I.I. oa niiaaao., 1988; Ia??nii O.C. oa
niiaaao., 1988) /e i?e?iaeii, ye, iai?eeeaae, aeueoa-oieioa?ie
(Iiaeaa?aciia I.A. oa niiaaao., 1992; Munrod L.H. et al., 1997).

Oe?iei aea/aeinue ieoaiiy i?i canoinoaaiiy iaeiiai aioeieneaeaioa i?e
ii?ooaiiyo i?ioeania IIE i?e ?icieo iaoieiaiyo. Aeaii i?i niieueia
canoinoaaiiy aeaio oa aieueoa aioeieneaeaioia ia/eneaiii (Aa?aeia TH.I.
oa niiaaao., 1995; Salabudeen A.K. et al., 1996). Aiaeiii, ui
aeei?enoaiiy aeaio oa aieueoa aioeieneaeaioia ia aea? noia?iiai aoaeoo
ia i?ioeane ia?ieneaeaoei? eiiiaeia (Aa?aiiaa AE.I. oa niiaaao., 1985).
Oey aeiy aaaaoia?aiia oa iio?aao? iiaeaeueoiai aea/aiiy. Ia
i?iaiaeeeinue aeineiaeaeaiiy ii aea/aiith aieeao iiiieo oa
aeueoa-oieioa?ieo i?e niieueiiio canoinoaaiii. Ca aeaieie I.A.Aieaiei oa
niiaaao. (1989) a oiiaao iaoieiai? i?e aaaaeaiii iiiiea i?aaiici a
ia?oo /a?ao ?aaeico? aiaeiaaiiee aioeieneaeaio aeueoa-oieioa?ie. Oiio
iiiie iaie canoiniaai ?acii c aeueoa-oieioa?ieii.

Canoinoaaiiy i?aia?aoia c iaoith ?aaoeyoei? iaiiiieo i?ioeania, iniaeeai
ei?aeoei? i?ioeano ia?aeeniiai ieeneaiiy eiiiaeia, ia? noaoe cia/iei
aianeii o ?ic?iaeo iaoiaaiaoe/ii iaa?oioiaaiiai eieoaaiiy NO?

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie oa oaiaie.

Aeena?oaoeieia ?iaioa aeeiiaia ye /anoea eiiieaenii?
i?ia?aie IAe?:

NI.03.04.0002.86 ? aea?ae?a?no?aoei? 01860042209 “Iienee
eioi?iaoeaiuoe?eoa?eaa aeey ioeaiee oyaeanoe o?aaiaoe/aneiai oiea” oa
“Iaoiaaiaoe/ia ei?aeoeiy eiiiaeii? ia?ieneaeaoei? a iiiea?aei ia
oeaieiiiio oa noaeeioeiiiio ?iaiyo iiiieii oa eiiiniiaie i?e no?ani oa
oioei” (1996-1998).

Iaoa iaoeiaiai aeineiaeaeaiiy.

Anoaiiaeoe oa?aeoa? aieeao iiiieo oa aeueoa-oieioa?ieo ia
i?ioeane ia?ieneaeaoei? eiiiaeia oa aiino oeeeei/ieo ioeeaioeaeia o
oeaieiao na?oey, ia/iiee oa e?iai a aeeiaiioei ?icaeoeo NO?.

Aeey aeinyaiaiiy oei?? iaoe aoee iinoaaeaii oaei
caaaeaiiy:

1. Aecia/eoe aiino i?iaeoeoia IIE – aei?iiaeo eii’thaaoia
iaiane/aieo aee?ieo eeneio (AeE IAEE), iaeiiiaiai aeiaeueaeaaiaeo
(IAeA), AIN – iniiaieo eiiiiiaioia: aeueoa-oieioa?ieo (OO),
noia?ieneaeaeeniooace (NIAe), aethoaoiiio, anei?aiiiai? eeneioe (AE),
oinoieiiiaeia o oeaieiao na?oey, ia/iiee oa e?iai o aeeiaiioei NO? (4
aiae. eiii?ani?, 2 oa 24 aiae. aeaeiii?ani?).

2. Aecia/eoe aiino oeeeei/ieo ioeeaioeaeia – oeeeei/iiai
3,5-aaeaiiciiiiiioinoaoo (oeAIO) oa oeeeei/iiai 3,5 –
aoaiiciiiiiioinoaoo (oeAIO) o oeaieiao na?oey, ia/iiee oa e?iai o
aeeiaiioei NO? (4 aiae. eiii?ani?, 2 oa 24 aiae. aeaeiii?ani?).

3. I?iaanoe ii?oieiai/ii aeineiaeaeaiiy (aeaeo?iiio oa naioiao
iie?ineiiith) ciii, ui aiaeaoaathoueny o oeaieiao na?oey, ia/iiee oa
e?iai o aca?iica’yceo c eiiiaeiith ia?ieneaeaoei?th o aeeiaiioei NO? (4
aiae. eiii?ani?, 2 oa 24 aiae. aeaeiii?ani?).

4. Aeineiaeeoe aieea iiiieo oa OO ia eiiiaeio ia?ieneaeaoeith o
oeaieiao na?oey, ia/iiee oa e?iai o aca?iica’yceo c eiiiaeiith
ia?ieneaeaoei?th o aeeiaiioei NO? (2 oa 24 aiae. aeaeiii?ani?).

5. Aeineiaeeoe aieea iiiieo oa OO ia aiino oeeeei/ieo ioeeaioeaeia
– oeAIO oa oeAIO o oeaieiao na?oey, ia/iiee oa e?iai o aeeiaiioei NO? (
2 oa 24 aiae. aeaeiii?ani?).

6.I?iaanoe ii?oieiai/ii aeineiaeaeaiiy (aeaeo?iiio oa naioiao
iie?ineiiith) oeaiei i?aaiia, ui aea/athoueny, ia oei aaaaeaiiy iiiieo
oa OO a aeeiaiioei NO? (2 oa 24 aiae. aeaeiii?ani?).

Iaoeiaa iiaecia ?iaioe

A aeaiie ?iaioi iaaoei iiaeaeueoee ?icaeoie aea/aiiy aieeao
aioeieneaeaioia ia i?ioeane IIE i?e NO?.

Aeyaeaii iaaiaeiii ?aiio caeiiiii?iinoi aeoeaaoei? i?ioeania
IIE, ii?ooaiue ooieoei? aioeieneaeaioii? nenoaie oa ciiie aiinoo
oeeeei/ieo ioeeaioeaeia o oeaieiao ia/iiee, na?oey oa e?iai i?e NO?.

Aia?oa aea/aii aieea iiiieo oa aeueoa-oieioa?ieo i?e
niieueiiio canoinoaaiii ia i?ioeane ia?ieneaeaoei? eiiiaeia oa aiino
oeeeei/ieo ioeeaioeaeia i?e NO?.

A?aei?/aii ii?oieiai/ii aioo?eoiueieeioeiii ciiie iaoiaeaie
naioiai? oa aeaeo?iiii? iie?ineiii? o ?icieo oieiaeo i?aaiao, ye?
iiaeoaa?aeaeothoue iaia?aiiaeano?oeoeaii i?ioeane i?e ia?ieneaeaoei?
eiiiaeia o aeeiaiioei ?? ?icaeoeo i?e NO?.

Aeyaeaii iaia?aiii?ioaeoi?ii aeanoeainoi iiiieo oa
aeueoa-oieioa?ieo i?e ?o niieueiiio canoinoaaiii, yei ni?eyee ciaioaiith
aeano?oeoeaieo i?ioeania o oeaieiao na?oey, ia/iiee oa e?iai.

Aia?oa aea/aii aieea iiiieo oa aeueoa-oieioa?ieo i?e
niieueiiio canoinoaaiii ia caieueoaiiy ?acenoaioiinoi i?aaiicio aei
o?aaie, ui aeyaeeinue o caieueoaiii o?eaaeinoi aeeooy aenia?eiaioaeueieo
oaa?ei i?e NO?.

Oai?aoe/ia oa i?aeoe/ia cia/aiiy ?iaioe

1.?acoeueoaoe aeineiaeaeaiiy aeicaieythoue ?aeiiaiaeoaaoe aeey
eeiii/ii? ai?iaaoei? niieueia canoinoaaiiy iiiieo oa aeueoa-oieioa?ieo
i?e NO?.

2.?acoeueoaoe ?iaioe iiaeooue aooe aeei?enoaii i?e aeeeaaeaiii
iaoieiai/ii? oiciieiai? o iaaee/ieo aocao, a oaeiae a eaai?aoi?iyo oa
eeiieeao, yei caeiathoueny aeineiaeaeaiiyi i?iaeai o?aaiaoe/ii?
iaoieiai?.

Oai?aoe/ii iieiaeaiiy aeena?oaoei? oi?iaaaeaeaii a o/aiaee
i?ioean eaoaae? iaoieiai/ii? oiciieiai? Aeiiaoeueeiai, Eoaainueeiai,
Caii?icueeiai oa Aeiii?iiao?ianueeiai iaaee/ieo oiiaa?neoaoia.

Eiie?aoiee iniaenoee aianie aaoi?a.

Aaoi?ii iniaenoi i?iaaaeaii aenia?eiaioaeueii aeineiaeaeaiiy
ii anoaiiaeaiith aiinoo i?iaeoeoia IIE, eiiiiiaioia AIN, oinoieiiiaeia
oa oeeeei/ieo ioeeaioeaeia o eaai?aoi?ieo oaa?ei i?e NO? ia oei
eiiieaeniiai aaaaeaiiy iiiieo oa OO oa aac iueiai. I?iaaaeaia noaoe/ia
ia?iaea ?acoeueoaoia.

Ii?oieiai/ii aeineiaeaeaiiy c?iaeaii ca aeiiiiiaith naioiaiai
oa aeaeo?iiiiiie?ineiii/iiai aeineiaeaeaiiy oeaio?aeueii?
iaoeiai-aeine?aeieoeueei?

eaai?aoi??? Aeiiaoeueeiai aea?aeaaiiai iaaee/iiai oiiaa?neoaoo ii.
I.Ai?ueeiai

(ea??aiee a?oie – e.a.i. Oaa/aiei I.?.).

Ia iiaenoaai io?eiaieo ?acoeueoaoia noi?ioeueiaaii aeniiaee oa
ioi?ieaii iaoeiai ioaeieaoei?.

Ai?iaaoe?y aeena?oaoe??

Iaoa??aee aeena?oaoei? aeiiia?aeaeenue ia:

IV Ananithciiio c’?caei iaoioiciieiaia (Eeoeiaa, 1989);

Iaeaniie iaoeia?e eiioa?aioei? aianoac?ieiaia oa ?aaiiiaoieiaia Eocaano
(Iiaieociaoeuee, 1989);

Iaeaniie iaoeiaie eiioa?aioei? ii?oieiaia (Aeiiaoeuee, 1989);

Ananithciiio neiiicioii “Aenia?eiaioaeueia oa eeiie/ia iaoioiciieiaiy
aeno?aiaeueieo oa oa?iiiaeueieo noaiia” (Iiaieociaoeuee, 1990);

Iaeaniie iaoeiaie eiioa?aioei? “Aeinyaiaiiy iieiaeeo a/aieo iaaeeeia o
i?aeoeeo ioi?iie caei?ia’y” (Aeiiaoeuee, 1990);

Iaeaniie iaoeiaie eiioa?aioei? i?enay/aiie 60-?i//th Aeiiaoeueeiai
iaaee/iiai iinoeoooo (Aeiiaoeuee, 1990);

Iiaeia?iaeiiio eiia?ani iaoioiciieiaia (Iineaa, 1991);

II iaoeiiiaeueiiio eiia?ani iaoioiciieiaia Oe?a?ie, i?enay/aiiio
100-?i//th aiae aeiy ia?iaeaeaiiy aeaaeaiiea Ne?ioeiiia I.I. (Ee?a,
1996);

XV c’?caei Oe?a?inueeiai oiaa?enoaa oiciieiaia (Aeiiaoeuee, 1998);

Iaoeiaie eiioa?aioei?, i?enay/aii? 100-?i//th aiae aeiy ia?iaeaeaiiy
i?ioani?a I.Ae.Aeiaayeei (Aeiiaoeuee, 1998).

Ioae?eaoe??.

Ca oaiith aeena?oaoei? iioaeieiaaii 13 ae?oeiaaieo ?ia?o, c
ieo 3 noaooi o oeaio?aeueieo aeo?iaeao i 2 o iaoeiaeo cai?eao.

No?oeoo?a aeena?oaoe?? oa ?? ianya.

Aeena?oaoeiy neeaaea?oueny c aaaaeaiiy, iaeyaeo eioa?aoo?e,
iieno iaoiaeia aeineiaeaeaiiy, ?icaeieia aeanieo aeineiaeaeaiue,
iaaiai?aiiy ?acoeueoaoia, caeeth/aiiy oa aeniiaeia.

Caaaeueiee ianya aeena?oaoei? neeaaea? 108 noi?iiie
iaoeiiieniiai oaenoo. Iethno?iaaiee iaoa?iae iiaeaii ia 6 iaethieao, 16
oaaeeoeyo, 10 aeaeo?iiii-i?e?ineii?/ieo oioia?ao?yo. Nienie eioa?aoo?e
neeaaea? 237 aeaea?ae, c ieo 81 iiicaiia.

INIIAIEE CIINO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy.

Aenia?eiaioaeueia /anoeia aeeiiaia ia aieeo uo?ao ianith
190-210 a, yei oo?eioaaeenue o noaiaea?oieo oiiaao aiaa?ith. Eiio?ieueii
oa iniiaii aeineiaee noaaeee iaeii/anii, caaaeath/e ia aeiaiai oa
naciiii eieeaaiiy aii?eoiia. Iiaeaethaaiiy NO? i?iaiaeeee
?ic/aaethaaiiyi i’yeeo oeaiei caaeiio eiioeiaie uo?ia i?ioyaii /ioe?ueio
aiae. ia iiaa?oii 6-10 ni2 o noaieao-aeiceiao?ao, cai?iiiiiaaieo
?euenueeei A.I. (1976) c iaiiiao?e/iei eiio?ieai neee ?ic/aaethaaiiy (4
ea/ni2).

Oaea eiii?aniy i’yeeo oeaiei caaeiio eiioeiaie uo?ia aeeeeea?
iiaiee eiiieaen ii?oiooieoeiiiaeueieo ciii, oa?aeoa?ieo aeey NO?
(?euenueeee A.I., 1977; Eoeaaii A.E., 1978). Aeineiaeaeaiiy ia oaa?eiao
i?iaiaeeee iiae aaenaiaeiaei ia?eicii o aeici 10 ia/ea.

Aeaeeaaiiy oaa?ei i?e aeaiiio aeaei iiaeaethaaiiy o?aaiaoe/iiai
oieo aecia/aeinue ia 2 a?oiao.

Oaa?eiai ia?oi? a?oie aaiaeeee aioo?eoiuei/a?aaeiii iiiie a
aeici 20 ia/ea oa OO o aeici 3 ia/ea /a?ac 4 aiae. eiii?ani? a iiiaio
ciyooy i?ana. Oaa?eiai ae?oai? a?oie aaiaeeee aioo?eoiuei/a?aaeiii
aiaeiai/iee ia’?i iei?. O?eaaeinoue aeineiaeo ia aeaeeaaiiy neeaea
i’youe aeia iiney onoiaiiy eiii?ani?. Aeineiaeaeaiiy noaio i?ioeania
ia?ieneaeaoei?, iaiiio oeeeei/ieo ioeeaioeaeia oa aoaeoeaiinoi ei?aeoei?
oeeo i?ioeania i?e NO? iiiieii oa OO i?e eiiieaeniiio aeei?enoaiii
i?iaiaeeeeny ia 9 a?oiao uo?ia. Aiae eiaeii? c 9 a?oi iaea?aeaii
ia?aeiii ianeae aeaieo c 10 aa?iaio. Oaa?ei aeaeaiiooaaee oa iae?aco
aiaeae?aee i?iae oeaiei na?oey, ia/iiee oa e?iai. Oeaieie aiiiaaiicoaaee
aeey iiaeaeueoiai aeineiaeaeaiiy.

Aeey ioeiiee noaio IIE aeei?enoiaoaaee iaoiaee aiioiii/ieo
aeineiaeia aiinoo AeE IAEE oa IAeA. Aiino AeE IAEE o oeaieiao na?oey,
ia/iiee oa e?iai aecia/aee ca Placer o iiaeeoieaoei? A.A.Aaa?eeiaa oa
niiaaao. (1983) ca aaee/eiith iieo iiaeeiaiiy eii’thaiaaieo aei?iiaeo
no?oeoo? aiae?iia?aeenia eiiiaeia o iaeanoi 232-234 ii ia
niaeo?ioioiiao?i NO-26.

Aecia/aee ai?no IAeA , yeee ooai?th?oueny o ?acoeueoao?
?aaeoei? e?ioeaaeo i?iaeoeo?a IIE c o?iaa?aioo?iaith eeneioith,
niaeo?ioioiiao?e/ii ca ?.Bernhelm et al. o iiaeeoieaoei?
TH.A.Aeaaeeie?iaa oa niiaaao.(1972) ca ?iaeaaei caaa?aeaiyi
o?eiaoeiiaiai eiiieaeno, ?ioaineai?noue yeiai aecia/a?oueny i?e
aeiaaeei? oaee? 540-580 ii.

Aeey ioeiiee noaio aioeieneaeaioii? nenoaie aeei?enoiaoaaee
iaoiaee aiioiii/ieo aeineiaeaeaiue aiinoo OO, AE, NIAe oa aethoaoiiio.

Aiino i?e?iaeiueiai aioeieneaeaioo OO aecia/aee iaoiaeii
I.Biery a iiaeeoieaoei? ?.O.Eenaeaae/ oa niiaaao.(1973). I?eioeei
iaoiaeo a?oioo?oueny ia caeaoiinoi OO aiaeiiaethaaoe oei?ia caeici o
i?enooiinoi iiaeeeaoi?o aeueoa-aeueoa-aeeia?eaeieo. I?e oeueiio
ooai?th?oueny ?iaeaaa caaa?aeaiiy, iioaineaiinoue yeiai aecia/a?oueny ia
niaeo?ioioiiao?i i?e 520 ii.

Aeoeaiinoue NIAe aecia/aee ca iaoiaeii N.*aaa?i oa niiaaao.
(1985). Iaoiae a?oioo?oueny ia oiio, ui i?e aca?iiaei?
aiaeiiaethaaeueii? oi?ie IAAeI oa oaiaceiiaoanoeueoaoo aaia?othoueny
noia?ieneaeii ?aaeeeaee, yei aiaeiiaeththoue i?o?ineiie oao?acieie (INO)
a aiae?aceioao?acieio. O i?enooiinoi NIAe aiaenioie aiaeiiaethaaiiy
i?o?ineiueiai oao?acieith ciaioo?oueny, ui anoaiiaeth?oueny
niaeo?ioioiiao?e/ii.

Eieueeiniee aiino anei?aiiiai? eeneioe aecia/aee ca J.H.Roe et
al. (1973) o iiaeeoieaoei? A.A.Nieieianueeiai oa niiaaao.(1973). Iaoiae
caniiaaiee ia aca?iiaei? 2,4-aeiiio?ioaiieaiae?aceio c aeaeaoiaoeiiiaith
eeneioith c ooai?aiiyi aiaeiiaiaeiiai icaciio, yei aeathoue /a?aiia
caaa?aeaiiy, ui aeei?enoiao?oueny aeey oioiiao?e/iiai aecia/aiiy
i?e 520 ii. C iaoith ia/eneaiiy noie eeneio ?o ieeneththoue ?ic/eiii
2,6-aeioei?oaiieiiaeioaiieo. AE aecia/a?oueny ca ?icieoeath.

Aecia/aiiy aiinoo aethoaoiiio i?iaiaeeee ca iaoiaeii
I.A.Ca?iiaa oa niiaaao.(1969) oioiiao?e/ii i?e aeiaaeeii oaee? 520 ii.

Aiino oinoieiiiaeia aecia/aany ca noaiaea?oieie iaai?aie
“Oast-Combination Phospholipide” i?iaoeueei? oi?ie “Boachringer Mannheim
Gmbh Diagnostica”.

Eiioeaio?aoeiy oeAIO oa oeAMO aecia/aeanue iaoiaeii
?aaeiiicioiiii? iioee, ca noaiaea?oieie iaai?aie “In vitro test [125 I]
RIAKIT”, ?ic?iaeaieie aeineiaeiei iinoeoooii ae?iaieoeoaa oa
canoinoaaiiy ?aaeiiicioiiia (I?aaa, *aoineiaa//eia).
?aaeeiaeoeaiinoue iiae?aoiaoaaeanue ia noeeioieyoeiiiiiio
aaoa-ei/eeueieeo “Rack Beta”.

Aeey naioiai? iie?ineiii? c iaoith aiaeico
ii?oiooieoeiiiaeueieo ciii o eeioeiao ia/iiee oa na?oey oiaoi/ee oeaiei
oienoaaee o 10% ?ic/eii iaeo?aeueiiai oi?iaeiio, caeeaaee a ia?aoii.
Ia?aoiiiai c?ice caaoiaoee 5-8 iei caaa?aethaaee aaiaoieneeiiii oa
aiceiii , iii?aaioaaee na?aa?ii .

Aeaeo?iiiiiie?ineiii/ia aeineiaeaeaiiy i?iaiaeeee ia
aeaeo?iiiiio iie?ineiii “Oanea”-AN-612 (*aoineiaa//eia) o oeaio?aeuei?e
iaoeiai-aeine?aeieoeuee?e eaai?aoi??? Aeiiaoeueeiai aea?aeaaiiai
iaaee/iiai oiiaa?neoaoo ii. I.Ai?ueeiai (ea??aiee a?oie – e.a.i.
Oaa/aiei I.?.).

Oiaoi/ee oeaieie ?iciiuoaaee o 2,5% ?ic/eio aeooa?iaiai
aeueaeaaiaeo

ia oinoaoiiio aooa?i(?I 7,4), iioii oienoaaee 1% ?ic/eiii /ioe?ueioieeno
iniith ia oiio ae aooa?i. Oeaieio ciaaiaeithaaee o nie?oao aenoiaeii?
eiioeaio?aoei? oa caeeaaee a Aiii-812. Iaiiaoiiei c?ice caaa?aethaaee 1%
?ic/eiii oieoiaeeiiaiai neiueiai, a oeueo?aoiiei – o?aiieaoeaoaoii i
oeeo?aoii naeioeth .

C iaoith ei?aeoei? aeyaeaieo aiioiii/ieo ii?ooaiue i?e
aenia?eiaioaeueiiio NO? aoee canoiniaaii i?aia?aoe iiiie (neioaoe/iee
aioeieneaeaio) o aeic? 20 ia/ea oa OO (i?e?iaeiie aioeieneaeaio) o aeic?
3 ia/ea .

Iiiie oa OO – oa?iaeieiai/ii i?aia?aoe, aeiiouaii
iiiinoa?noaii ioi?iie caei?ia’y aei aeei?enoaiiy o e?eoaaeueieo
caeeaaeao.

I?e noaoe/iie ia?iaoei aenia?eiaioaeueiiai iaoa?iaeo
ea?oaaeeny iaoiaee/ieie aeaciaeaie ca iniiaieie i?eeiiaie noaoenoe/iiai
aiaeico a aiieiai/ieo oa iaaee/ieo aeineiaeaeaiiyo (Aai/eeia A.I., 1974;
O?aao A.TH., 1975; Aaeei I., 1979). Iaie aecia/aia na?aaeiy a?eoiaoe/ia
aaee/eia aeai?ee (I), eaaae?aoe/ia aiaeoeeaiiy (G), iiieeea na?aaeiuei?
a?eoiaoe/ii? (m), iieaciee nooo?ainoi ?icieoeue (t). Ia iniiai aaee/ei t
oa /enea niinoa?aaeaiue iieacaee iiiai?iinoue ?icieoeue (?) ca
oaaeeoeath No’thaeaioa. ?icieoey aaaaeaeany aeinoiai?iith, ii/eiath/e ci
cia/aiiy ?

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