IIIINOA?NOAI IOI?IIE CAeI?IA’ss OE?A(IE

AIIIEOeUeEEE AeA?AEAAIEE IAAeE*IEE OIIAA?NEOAO

ii. I.I. IE?IAIAA

OOOI?IEE NA?AIE IEOAEEIAE*

OAeE 618.3 — 06 :
616.155.194.8 : 612.017.1

NOAI IIOIII( NENOAIE I

INIAEEAINOI II?OIEIAI( IA?EOA?E*II( E?IAI

I?E CAEICIAeAOIOeEOIIE AIAII( AAAIOIEO

14. 01. 01 — aeooa?noai oa aiiaeieiaiy

AAOI?AOA?AO

aeena?oaoei( ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

AIIIEOess — 1999

Aeena?oaoei(th ( ?oeiien

?iaioa aeeiiaia ia eaoaae?i aeooa?noaa oa aiiaeieiai( ?2 Ee(anueei(

iaaee/ii( aeaaeaii( iineyaeeieiiii( inaioe ii. I.E. Ooieea IIC Oe?a(ie

Iaoeiaee ea?iaiee: aeieoi? iaaee/ieo iaoe, i?ioani?

Eaoo Noaiineaa Na?aieiae/,

Ee(anueea iaaee/ia aeaaeaiiy
iineyaeeieiiii(

inaioe IIC Oe?a(ie, caaiaeoaa/
eaoaae?e

aeooa?noaa oa aiiaeieiai( ?2

Ioioeieii iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani?

Iena?(aa Naioeaia Iao?iaia,

Iinoeooo iaaeiao?i(, aeooa?noaa
oa

aiiaeieiai( AII Oe?a(ie,

caaiaeoth/a aiaeaeieaiiyi
iaoeiaeo i?iaeai

iaaeiiooaaiiy aaaioiinoi

aeieoi? iaaee/ieo iaoe, i?ioani?

Aaeno?oe Aiaoieie Ieeeoi?iae/,

Aiiieoeueeee aea?aeaaiee
iaaee/iee

oiiaa?neoao IIC Oe?a(ie,
caaiaeoaa/

eaoaae?e aeooa?noaa oa
aiiaeieiai( ?2

I?iaiaeia onoaiiaa: Iaoeiiiaeueiee iaaee/iee oiiaa?neoao

ii. aeaae. I.I. Aiaiiieueoey,

eaoaae?a aeooa?noaa oa
aiiaeieiai( ?1

Caoeno aiaeaoaeaoueny “ 23 “ ethoiai 1999 ?. i 12 00 aiaeeii
ia caniaeaiii niaoeiaeiciaaii( a/aii( ?aaee E 05. 600. 01 i?e
Aiiieoeueeiio aea?aeaaiiio iaaee/iiio oiiaa?neoaoi ii. I.I. Ie?iaiaa (
286018, i. Aiiieoey, aoe. Ie?iaiaa, 56 ).

C aeena?oaoei(th iiaeia iciaeiieoenue o aiaeiioaoei Aiiieoeueeiai
aea?aeaaiiai iaaee/iiai oiiaa?neoaoo ii. I.I. Ie?iaiaa ( 286018, i.
Aiiieoey, aoe. Ie?iaiaa, 56 ).

Aaoi?aoa?ao ?icineaiee “ 20 “ ni/iy 1999 ?.

A/aiee nae?aoa? niaoeiaeiciaaii( a/aii( ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio Iieeaeueei I.I.

CAAAEUeIA OA?AEOA?ENOEEA AeENA?OAOeI(

Aeooaeuei?noue oaie. Na?aae i?iaeai no/aniiai aeooa?noaa aiai?y aaa?oieo
? iaei??th c aaaeo/eo. Ca aeaieie ??cieo aaoi??a oneeaaeiaiiy
aanoaoe?eiiai i?ioeano aiai??th cono??/a?oueny o 15 — 83,1% aaa?oieo (
O.I. Aaniaa e niaao., 1990; O.A. Noa?inoeia, I.A. O?ieiaa, 1990; A.E.
Noaiaieianueea, 1992; W.K. Simons, 1994 ). Aenia?oaie AIOC ( 1991 )
aiai?y aeyaeaia o 51% aaa?oieo ae?iie o na?o?.

Inoeiia aiai?y aaa?oieo cae/aeii ?icaeaa?oueny a ae?oa?e iieiaei?
aaa?oiino? ? a?eueoa, i?ae o 90% ? cae?ciaeao?oeeoiith ( N.I. Eaooiai,
A.Ae. Aeieaaaaa, 1987; A.N. Ii?aeooiae/ e niaao., 1991; E.A. Oeiioaiei,
Oaeaae — Aeue -O?aenao, 1993 ).

Ca inoaii? 10 ?ie?a /anoioa caeiciaeaoioeeoii( aiaii( ( CAeA ) aaa?oieo
a Oe?a?i? cia/ii ae?inea: A.ss. Nai/oe i niiaaao. aeyaeee ca?eueoaiiy
CAeA aaa?oieo c 1,7 aei 57% ( 1984 — 1993 ); ca aeaieie ?inoeoooo
iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie ( 1985 — 1996 )
e?euee?noue aiai?e ca?eueoeeanue iaeaea o 8 ?ac?a ( a?ae 6,5 aei 51,2%
). Oaeei /eiii, oi/ aiai?y aaa?oieo iienaia Y. Andral aeecueei 150
?ie?a oiio, i?iaeaia caa??aa? aeooaeuei?noue ? nueiaiaei? a ca’yceo c
iioe?aiiyi oa ?eceeii aaaeeeo iane?aee?a aeey caei?ia’y iaoa?? ? ieiaea
( i?ci? aanoice, iaaeiiiooaaiiy, aaaaoiaiaeaey oa ianai?/ania
a?aeoiaeaeaiiy iaaeieiie?aeieo aiae, neaae?noue iieiaiai? ae?yeueiino?,
e?iaioa/?, a?iien?y e a?iio?io?y ieiaea ( I.I. Oaooiai, O.I. Aa?oaoiaa,
1982; TH.E. Aeaeaaaa?iaa, 1987; A.I. Oa?eaiie, 1990; A.A. Aioaeeianeay,
1993; A.I. Aeaieaeia e niaao., 1994; A. Papina et al., 1991; L.H. Allen,
1993 ).

Aaaaoi ieoaiue, cie?aia, i?e/eie aeieeiaiiy, no?iee e iaoai?ci ?icaeoeo,
ee?i?/i? iniaeeaino? CAeA aaa?oieo ? iniaeeaino? e?eoaaiiy oai?eo
caeeoathoueny i?aaeiaoii aeeneon??, a, ioaea, iio?aaothoue iiaeaeueoiai
iiiiaiaiiy aace aeaieo ? ?aa?c?? iayaieo.

Ii?iaeueiee ia?aaia aanoaoe?eiiai i?ioeano iaoiiaeaiee eiiieaenii
?ioiieia?/ieo ? iae?iaiaeie?eiieo iaoai?ci?a, ye? ia?aoeiaeaeathoue
i?iyao ?aaeoe?e o?ainieaoeaioa?iiai ?ioi?oaoo ( A.E. Aiaaeei, 1987; ?.A.
Iao?ia e niaao., 1992; E.A. Oiaaaeue, 1994; S. Asari et al., 1998; W.D.
Billington, 1989; B.M. Sibai, 1991 ).

I?ae /an aea/aiiy aoiieia?? ? iaoiaaiaco CAeA aaa?oieo cia/ia i?noea
a?aeaaaeaii ?ie? ee?oeiii — aoii?aeueieo ?aaeoe?e ?ioi?oaoo. I?e oeueiio
?ioiieia?/ia oiea?aioi?noue, aeanoeaa ii?iaeuei?e aaa?oiino?, i?e CAeA
aaa?oieo iaaoaa? oa?aeoa?o ?ioiieia?/iiai eiioe?eoo ?c aoyaiaiiyi aei
i?ioeano iaeii/anii c ?ioeie nenoaie aaiiiiaco ( Ae. ss. Aeeieo?ia, 1980
).

A?aeiiino?, ui noinothoueny oa?aeoa?enoeee ee?oeiii? ? aoii?aeueii?
eaiie ?ioi?oaoo i?ae /an aaa?oiino?, yea i?ioiaeeoue o?c?ieia?/ii, ?
oneeaaeiaii? CAeA oi/ ? /eneaii?, aea iaiaeiicia/i? e /anoi noia?a/eea?.
Aeaye? aeine?aeaeaiiy i?iaaaeai? aac o?aooaaiiy ia??iaeo aaa?oiino?,
aeeiai?ee aaiia?aie i?e CAeA ? nooiaiy oyaeeinoi aiai??.

Iaae??oaiei oaeiae ? ieoaiiy i?i e?eoaaiiy aaa?oieo ?c CAeA.
Caaaeueiii?eeiyo? iaoiaee e?eoaaiiy ia caaaeaee aoaeoeai?. Oiio, ii?yae
?c o?aaeeoe?eiith aioeaiai?/iith oa?ai??th, ieoaiiy iiooeo iiaeo
aoaeoeaieo iaoiae?a e?eoaaiiy aaa?oieo ?c CAeA aeooaeueia ? a oaia??oi?e
/an.

?icaeyaeath/e aaaee? oi?ie CAeA ye i?ci?e aanoic ( TH.E. Aeaeaaaa?iaa,
1990 ), canoiniaothoue iaoiaee aeaoieneeaoe?eii? oa?ai?? ( A.E.
Noaiaieianueea i niiaaao., 1988; O.O. Ia/a?, 1991 ), ?ioiiei?aaoth/o oa
ai?iiiaeueio oa?ai?th ( A.A. Ea?iaiei, 1994; C.A.
Oiiiinea i niiaaao., 1994 ), eaca?ia ii?ii?iaiiy e?ia? ( A.ss. Nai/oe,
1996 ), inoaii?i /anii c’yaeeenue iiiaeeiiei ?iaioe i?i canoinoaaiiy a
aeooa?nueei — a?iaeieia?/i?e i?aeoeoe? aieei?aoeaenioa?ai??
( A?O ) ( Ae.A. Aciaaoeiaa e niaao., 1989; I.I. Eieaniee, 1992; A.I.
Iaooea, 1992; A.I. Eieiiae/oe, 1998 ).

Oaeei /eiii, neeaaei?noue aoiieia?? ? iaoiaaiaco CAeA aaa?oieo,
?ica?aei?noue ?acoeueoao?a aeine?aeaeaiue ? aeniiae?a, iaaeinoaoiy
aoaeoeai?noue e?eoaaiiy oe??? iaoieia??, a oaeiae iacaia?a/iee oaeo, ui
CAeA aaa?oieo ? aaaiiei oaeoi?ii ?eceeo aeieeiaiiy aeooa?nueei? oa
ia?eiaoaeueii? iaoieia?? ? i?e/eiith ia?eiaoaeueieo ao?ao, niiioeaee aei
aeai?o oaie oeueiai aeine?aeaeaiiy.

Aeena?oaoe?eia ?iaioa ? caeii/aiei iaoeiaei aeine?aeaeaiiyi, aeeiiaia ia
eaoaae?? aeooa?noaa oa a?iaeieia?? ?2 Ee?anueei? iaaee/ii? aeaaeai??
i?neyaeeieiiii? ina?oe IIC Oe?a?ie a?aeiia?aeii aei ieai?a iaoeiai
— aeine?aeieo ?ia?o aeaaeai?? oa aea?aeaaieie ieaiaie ( ?
aea?ae?a(no?aoei( 0196U023574 ). Oaia aeena?oaoe?? caoaa?aeaeaia ia
can?aeaii? a/aii? ?aaee Ee?anueei? iaaee/ii? aeaaeai?? i?neyaeeieiiii?
ina?oe IIC Oe?a?ie, i?ioieie ? 3 a?ae 6 aa?aciy 1996 ?.

Iaoa aeine?aeaeaiiy. Ciaioeoe /anoioo CAeA o aaaioieo ia?aae iieiaaie
oeyoii aaeineiiaeaiiy inioth/i( oa?aii( c o?aooaaiiyi iioiiiai noaoono
oa ii?oieiai/ieo iniaeeainoae ia?eoa?e/ii( e?iai i?e aeaiie iaoieiai(.

A?aeiia?aeii aei iinoaaeaii? iaoe noi?ioeueiaai? iniiai? caaea/i
aeine?aeaeaiiy.

O aeiiie ic ii?iaeueiei ia?aaiaii aaaioiinoi i aaaioiinoth,
oneeaaeiaiith CAeA aea/eoe:

1. Eeiii/iee ia?aaia aaaioiinoi, iieiaia i iineyiieiaiaiai ia?iiaeo;

2. Noai eeioeiiiai i aoii?aeueiiai iioiioaoo ic o?aooaaiiyi
iniaeeainoae, eieueeinii? oa?aeoa?enoeee eeioeiieo i aoii?aeueieo
?aaeoeie;

3. Eieueeinii oa yeinii iciaee aoii?aeueii? naineaieicaoei? oeyoii
aecia/aiiy aioeeaeeioeeoa?ieo aioeoie;

4. Ii?oieiai/io oa?aeoa?enoeeo ia?eoa?e/ii? e?iai;

5. Aieea ?aeiiaiaeiaaii? oa?aii? ia eeiii/ii iniaeeainoi ia?aaiao
aanoaoeieiiai i?ioeano, iieacieee iioiioaoo oa aaiiiiaoe/ii oaeoi?e
ia?eoa?e/ii? e?iai, aecia/eoe ?? aoaeoeaiinoue o eiiieaeni eieoaaiiy
CAeA.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. Ia iniia? aeyaeaieo e?euee?nieo
? ye?nieo ci?i o ?ioiiiio aiiainoac? aaa?oieo ?c CAeA noi?ioeueiaaia
iaoiaaiaoe/ia eiioeaioe?y aaiiaanoico, yea aeieeaa? ?c ee?i?ee CAeA,
ae?aaeaieo iaoieia?/ieo a?aeoeeaiue o ee?oeii?e ? aoii?aeuei?e eaieao
?ioi?oaoo, a naia: ?ioiiaeao?oeeoo O — ? A — nenoai ?ioi?oaoo, ?icaeoeo
aeeni?iii?oe?? ?ioii?aaoeyoi?ieo ee?oei ?c i?aeneeaiiyi oaeia?iiai oa
aeao?oeeoii noi?ani?iiai aieeao; iiyae iciae iaoieia?? i?ioyaii
ee?oeiii -?ioiieo ?aaeoe?e oa aoii?aeueii? nainea?e?caoe?? i?aai?cio
aaa?oii?; iaoieia?/ieo c?ooaiue o ?aaoeyoe?? nenoaie aioeaai — aioeo?ei;
cieaeaiiy ooieoe?iiaeueii? aeoeaiino? O — ? A — nenoai ?ioi?oaoo, ui
oneeaaeith?oueny oyaee?noth aiai??. Ioaea, ci?ie a ?ioiiiio aiiainoac?,
i/aaeaeii, ? ioneiaei iaoai?ciii i?eai?/aiiy ii?yae c ?ioeie nenoaie
aaiiiiaco c ?icaeoeii eeiiiei — iioiiiaoieiai/iiai noaio — aaiiaanoico
aaa?oieo.

?ic?iaeaii iaoiae iaoiaaiaoe/iiai e?eoaaiiy CAeA aaa?oieo ?c
aeei?enoaiiyi ?ioiiiiaeoethth/iai aoaeoo A?O.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Cai?iiiiiaaia iaoiaaiaoe/ia
eiioeaioe?y CAeA aaa?oieo ye ee?i?ei — ?ioiiiaoieia?/iiai noaio —
aaiiaanoico ae?oai? iieiaeie aaa?oiino?, yeee i?iyaeany ?ioiieia?/iith
a?ii?aaeoeai?noth i?aai?cio aaa?oieo ?c CAeA, aeeeeea? iaiao?aei?noue
iiooeo iiaeo cania?a ? iaoiae?a ?? noeioethaaiiy aei ??aiy o?c?ieia?/ii?
oiea?aioiino?.

A aeooa?nuee?e i?aeoeoe?, aa?o/e aei oaaae ?ecee iicaoa?aiaaoe/ieo
aoaeo?a o?i?ioa?ai??, aeioe?eueii o eiiieaen e?eoaaiiy CAeA aaa?oieo
ai?iaaaeeoe A?O ye aoaeoeaiee cania aeoea?caoe?? ?ioi?oaoo,
ii?iae?caoe?? ?ioiieia?/ieo iieaciee?a, a, a?aeiia?aeii, cieaeaiiy
iaoa?einueei( ?ioiii( a?aeiiaiaei ia ie?ae.

Iniiai? iieiaeaiiy aeena?oaoe?? ai?iaaaeaeai? o i?aeoeeo iieiaiaiai
aoaeeieo ICC no. Ee?a, ae?ii/i? eiinoeueoaoe?? Oeaio?aeueii? caeicie/ii?
ee?i?/ii? e?ea?i? ?1 ICC no.Ee?a, iieiaiaiai aoaeeieo ?4 i. Ee(aa,
Oeaio?aeueii( iinueei( eeiii/ii( eiea?ii.

Iaoa??aee aeine?aeaeaiue aeeth/ai? aei eaeoe?eiiai eo?no oa i?aeoe/ieo
caiyoue aeey e?ea??a — neooa/?a eaoaae?e aeooa?noaa oa a?iaeieia?? ?2
EIAII.

Iniaenoee aianie aeena?oaioa. Aaoi?ii iniaenoi i?iaaaeaii eeiii/ia
niinoa?aaeaiiy oa ee?i?ei — eaai?aoi?ia ianoaaeaiiy 135 aaa?oieo o ?icii
ia?iiaee aanoaoeieiiai i?ioeano, o 99 c ieo aeyaeaia CAeA ?iciiai
nooiaiy, 36 caei?iaeo aaaioieo, a oaeiae 12 iaaaaioieo aeiiie.

A?eueoa /anoeia eaai?aoi?ieo aeine?aeaeaiue aeeiiaia aaciina?aaeiuei
aaoi?ii /e ca eiai o/anoth. Naiino?eii i?iaaaeaii e?eoaaiiy aaa?oieo ?c
CAeA c aeei?enoaiiyi o eiiieaeniiio e?eoaaiii iaoiaeo A?O.

?acoeueoaoe ee?i?ei — noaoenoe/ii? ia?iaee iaea?aeaieo ?acoeueoao?a oa
?o iaoeiaee aiae?c aeicaieeee aaoi?o noi?ioethaaoe iaoiaaiaoe/io
eiioeaioe?th CAeA aaa?oieo ye aaiiaanoico.

Ia iniia? iaoaiaoe/ii — noaoenoe/ii? ia?iaee, ocaaaeueiaiiy e iaoeiaiai
aiae?co iaa?oioiaai? aeniiaee oa i?aeoe/i? ?aeiiaiaeaoe??.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee aeena?oaoe??
iaaiai?thaaeeny ia can?aeaii? iaoeiai? ?aaee iaae?ao?e/iiai oaeoeueoaoo
EIAII, ia iaoeia?e eiioa?aioe?? EIAII ii iane?aeeao cae?i/aieo iaoeiaeo
?ia?o o 1997 ?ioe?, ia iaoeiai — i?aeoe/ieo eiioa?aioe?yo OII
Aei?i?ianueeiai ?aeiio i. Ee?aa i?ioyaii /ano aeeiiaiiy, ia can?aeaii?
i?iaeaiii? eii?n?? “ Aeooa?noai ? a?iaeieia?y “ ( /a?aaiue,
1998 ). Iniiaii iieiaeaiiy aeena?oaoe?? aeei?enoaii o iaa/aeueiiio
i?ioean? ia oeeeeao oaeineiiaeaiiy e?ea??a.

Ioae?eaoe??. Ii oai? aeena?oaoe?? iioae?eiaaii 5 iaoeiaeo i?aoeue ?
ai?iaaaeaeaia a i?aeoeeo iaeia ?aoe?iiae?caoi?nueea i?iiiceoe?y.

No?oeoo?a ? ianya aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 170 noi??ieao
iaoeiiieno i neeaaea(oueny ic anooio, iaeyaeo e?oa?aoo?e, oinoe
?icae?e?a aeanieo aeine?aeaeaiue, iaaiai?aiiy iaea?aeaieo ?acoeueoao?a,
aeniiaeia, i?aeoe/ieo ?aeiiaiaeaoe?e, a?ae?ia?ao?/iiai iieaae/eeo c 197
aeaea?ae c e?a?i NIAe oa 83 ?iicaiieo. ?iaioo ?ethno?iaaii 27 oaaeeoeyie
oa 24 ?enoieaie.

INIIAIEE CIINO ?IAIOE

Iaoa??ae ? iaoiaee aeine?aeaeaiiy. Ianoaaeaii 135 aaa?oieo o a?oe? aei
30 ?ie?a — 107 ( 79,3% ) ? i?ney 30 — 28 ( 20,7% ) o ??ci? ia??iaee
aanoaoe?? oa 12 iaaaa?oieo ae?iie ( eiio?ieueia a?oia ?1 ). O 99
aaa?oieo aeyaeaii CAeA ??ciiai nooiaiy oyaeeino? ( iniiaia a?oia ), c
ieo aia?oa ia?iaeaeothoue — 67 ( 67,7% ), iiaoi?ii — 32 ( 32,3%
), 36 aaa?oieo ae?iie ( eiio?ieueia a?oia ? 2 ), aac iciae aiai??. On?
aaa?oi? niiaoe/ii caei?ia?, iieaciee?a aiai?? aei oaia?ioiuei?
aaa?oiino? o aeiaeii? ?c ianoaaeaieo ae?iie ia aoei.

Na?aae oai?eo aiai??th — 52 ( 52,5% ) ?c CAeA ( nooiaiy ( Hb 110 —
91 a/e ); 33 ( 33,3% ) ?c CAeA (( nooiaiy ( Hb 90 — 81 a/e); 14 (
14,2% ) aaa?oieo ?c CAeA ((( nooiaiy oyaeeino? ( Hb 80 a/e ? iaioa ).

25 aaa?oiei ?c CAeA a eiiieaen? ?c o?aaeeoe?eiei iaoiaeii e?eoaaiiy
canoiniaaia A?O. Aeey i?aeoaa?aeaeaiiy ?? aoaeoeaiino? oai?ei i?ney
e?eoaaiiy o?aaeeoe?eiei iaoiaeii ( eiio?ieueia a?oia ?3 ) ?c
canoinoaaiiyi A?O i?iaaaeaii aeine?aeaeaiiy iieaciee?a ia?eoa?e/ii?
e?ia? oa iniiaieo ia?aiao??a ee?oeiiiai ? aoii?aeueiiai ?ioi?oaoo.

Aeey aea/aiiy noaio ?ioiieia?/iiai aiiainoaco i?iaaaeai? iaoiaee
aeine?aeaeaiiy eeioeiiiai oa aoii?aeueiiai iioiioaoo caaaeueiii?eeiyoeie
iaoiaeeeaie ca aeiiiiiaith ?aaeoe?? ?icaoeiooai?aiiy ?c enaiiaaiieie
a?eo?ioeeoaie ( A — ?OE ( O — eiioioeeoe ), Aa — ?OE ( O — aeoeaii
eiioioeeoe ), O( — oaeia?e, O( — noi?ani?e, AAN — ?OE ( A — eiioioeeoe
) ). Ooieoe?iiaeueiee noai O — nenoaie ?ioi?oaoo aecia/aany caeaoi?noth
A — ?OE aei i?ie?oa?aoe?? i?ae aieeaii o?oiaaiaaethoeieio ( OAA ) a
?aaeoe?? aeanoii? o?ainoi?iaoe?? e?ioioeeo?a ( ?AOE ) oa
nainea?e?caoe??th iaoa?einueeiai i?aai?cio aei aioeaai?a ( AA ) o
?aaeoe?? aaeueioaaiiy i?a?aoe?? eaeeioeeo?a ( ?AIE ). Oee?eoethth/i
iioii? eiiieaene ( Oe?E ) aeine?aeaeai? iaoiaeii ?aaeoe?? inaaeaeaiiy
iie?aoeeaiae?eieai 6000 “ Serva “, ai?no ?ioiiaeiaoe?i?a ( lgA, lgM,
IgG ) — iaoiaeii ?aae?aeueii? ?ioiiaeeooc??.

A ?iaio? aeei?enoai? eeane/i? iaoiaee ?c iiaeeo?eaoe?yie, caiice/aieie
?c iaoiaee/ieo iin?aiee?a oa ?aeiiaiaeaoe?e I.A. Aaca?iiai? oa A.O.
Ii?iciai? ( 1988 ), ?.A. Iao?iaa ? ni?aaao. ( 1992 ), ?.A. Aaiaeoeueeiai
( 1987 ). Aeine?aeaeaiiy aioeeaeeioeeoa?ieo aioeo?e ( AO ) i?iaaaeaii ca
iaoiaeeeaie Eai?ia?aaenueeiai IAe? aaiaoieia?? oa ia?aeeaaiiy e?ia? (
1985 ), aecia/aiiy eaeeiaaethoeiii?a o ?aaeoe?? eaeeiaaethoeiaoe??,
e?ioioeeoioienei?a o e?ioioeeoioiene/iiio oano? ca /eneii i?ioa?aiaaieo
e?ioioeeo?a, eaeeie?cei?a — oeeoieia?/iei i?ae?aooieii aeeaeo ?
e?ciaaieo eaeeioeeo?a.

Aeey aeine?aeaeaiiy iieaciee?a ii?oieia?/iiai neeaaeo ia?eoa?e/ii? e?ia?
aeei?enoaiee aaiaoieia?/iee aiae?caoi? SYSTEM 9000 Diff Model Serono —
Baker Diagnostics Inc., ca aeiiiiiaith yeiai aaoiiaoe/ii aecia/aee 18
ia?aiao??a ee?oei cooe?eueii? e?ia?.

Iaea?aeai? aeai? ia?iaeaii iaoiaeaie aa??aoe?eii? noaoenoeee oa
ei?aeyoeieiiai aiaeico ?c aeei?enoaiiyi t — e?eoa??th Nouethaeaioa oa
eiaoioei(ioo ei?aeyoei? ( E.N. Eaieineee, 1964; I.I. Ieioea? e ciaao.,
1991 ).

Iniiai? ?acoeueoaoe aeine?aeaeaiiy. I?ae /an aaa?oiino?, oneeaaeiaii?
CAeA, O — ? A — nenoaie ?ioi?oaoo caciathoue ?noioieo ci?i. Iaea?aeai?
aeai? na?ae/aoue i?i a?eueo ae?aaeaio a?ii?aaeoeai?noue O — ee?oeiiiai
?ioi?oaoo o aaa?oieo ?c CAeA ii??aiyii ?c oaeith o caei?iaeo aaa?oieo.
I?e/iio, yeui o aeeiai?oe? iaoneeaaeiaii? aaa?oiino? ai?no A — ?OE
iinooiiai ciaioo?oueny, oi i?e CAeA ?ioiiaeao?oeeo iiaeeaeth(oueny
i?iii?oe?eii oyaeeino? aiai??.

0,55, 26,1%, ? < 0,05. Aiaeii/an ??aaiue Aa - ?OE a aeeiai?oe? iaoneeaaeiaii? aaa?oiino? iinooiiai ia?inoa?; i?e CAeA oe? c?ooaiiy ?noioii oiia?eueiththoueny ?, caeaaeii a?ae nooiaiy oyaeeino? aiai??, o o?aoueiio o?eiano?? iieacieee Aa - ?OE ciaioothoueny ii??aiyii c oaeeie o caei?iaeo aaa?oieo ia 7; 18,6 ? 36,2% ( ? < 0,05 ). I?e ii??aiyii? ci?i iieaciee?a A - ?OE ? Aa - ?OE o ae?iie c iaoneeaaeiaiith aaa?oi?noth o o?aoueiio o?eiano?? noaoenoe/iee aiae?c aeyaea aenieee nooi?iue u?eueiino? cai?ioiuei? ei?aeyoe?eii? caeaaeiino? ( r = - 0,76 ), o oie /an, ye i?e CAeA aaa?oieo ia oii? aeao?oeeoo A - ?OE ?icaeaa?oueny ?ioiiaeao?oeeo Aa - ?OE ?c iii?oiei i?yiei nooiaiai ca’yceo ( r = + 0,53 ), ei?aethth/ei ?c oyaee?noth iaoieia?/iiai i?ioeano. Ioaea, yeui /anoeiaee aeao?oeeo O - nenoaie ?ioi?oaoo, yeee iai?/a?oueny i?e o?c?ieia?/iiio ia?aaiao aaa?oiino?, ia? ia a?eueoa, i?ae caoenii -i?enoinoaaeueiee oa?aeoa?, oi i?ae /an CAeA aaa?oieo iineeaiiy ?ioiiaeao?oeeoo ia? i/aaeaei? iciaee iaoieia??. A ?ioiiiio aiiainoac? i?e CAeA aaa?oieo ia oii? ae?aaeaiiai ?ioiiaeao?oeeoo iiioeyoe?eiiai neeaaeo O - nenoaie, ca ?acoeueoaoaie iaoeo aeine?aeaeaiue, a?aeaoaathoueny ?noioi? c?ooaiiy a ?aaoeyoe?? ?ioiii? a?aeiia?aei ia?a?iciiae?eii ?ioiieiiiaoaioieo ee?oei. 0,32, ? < 0,05 ). 0,40, ? < 0,05 ), oi i?e CAeA na?aaeiueiai nooiaiy e?euee?noue O( cieceeany ia 8,8%, O( - ia 14,5%, i?e oyaeeiio nooiaii CAeA - a?aeiia?aeii ia 8,9 ? 4,3%. Oaeei /eiii, i?e CAeA aaa?oieo ci?ie a aoii?aeueieo eaieao ?ioiii? a?aeiia?ae? iathoue iciaee iaoieia?? ca ?aooiie ii?ooaiiy ni?aa?aeiioaiiy ?aaoeyoi?ieo O - ee?oeiieo noaiiioeyoe?e c i?aeneeaiiyi oaeia?iiai oa aeao?oeeoii noi?ani?iiai aieeao ia o?ae aaa?oiino?. Cia/aiiy iieaciee?a aeeni?iii?oe?? O( ? O( o o?aoueiio o?eiano?? i?e CAeA na?aaeiueiai ? oyaeeiai nooiaiy iathoue cai?ioio ei?aeyoe?eio caeaaei?noue, i?iii?oe?iiaeueio nooiaith oyaeeino? CAeA; r = - 0,43; - 0,47, a?aeiia?aeii, ui aiaeaeaa( iii??io u?euei?noue ca’yceo. Eia?/iei i?aeoaa?aeaeaiiyi neacaiiai aeua ? iieacieee ?ioaa?aeueiiai eiao?oe??ioa O( : O(. sseui i?e aaa?oiino?, yea i?ioiaeeoue ii?iaeueii, aeey iueiai oa?aeoa?iee i?e?iaeiee iecueeee ??aaiue, oi aaea i?e CAeA eaaeiai nooiaiy aeinoia??ia cieaeaiiy a?aei?/aii eeoa o ae?oaiio oa o?aoueiio o?eiano?ao. I?e na?aaeiueiio ? oyaeeiio nooiai? CAeA eiao?oe??io O( : O( a i?ioean? aaa?oiino? i?aeoe/ii ia ci?ith?oueny, ui na?ae/eoue i?i ?icaeoie aeeni?iii?oe?? ?ioii?aaoeyoi?ieo ee?oei ? i?aeoaa?aeaeo? oaeo iaoieia?/ieo iciae o ?o ia?a?iciiae?e?. Aiae?c aeeeaaeaieo aeua oaeo?a i?i ci?ie ooieoe?iioaaiiy O - nenoaie ?ioi?oaoo i?e CAeA aaa?oieo aea? iiaeeea?noue ?icaeyaeaoe ?o ye i?iya ee?i?ei - ?ioiiiaoieia?/iiai noaio, yeee ie ioeiith(ii ye aaiiaanoic aaa?oieo. ?acoeueoaoe i?iaaaeaieo aeine?aeaeaiue na?ae/aoue, ui i?e ianiaoeeo?/i?e noeioeyoe?? o aaa?oieo ?c CAeA ci?ith?oueny ooieoe?iiaeueia aeoeai?noue e?ioioeeo?a, ui noi?iaiaeaeo?oueny ?icaeoeii iciae iaoieia?? ia?aaiao ee?oeiii - ?ioiieo ?aaeoe?e. Anoaiiaeaii, ui i?ie?oa?aoeaia aeoeai?noue ia OAA a ?AOE i?e CAeA aaa?oieo eaaeiai nooiaiy ii??aiyii c oaeith o caei?iaeo aaa?oieo o aeeiai?oe? i?ia?anoaaiiy aaa?oiino? i?aeoe/ii ia ci?ith?oueny. Aiaeii/an i?e CAeA na?aaeiueiai nooiaiy o ae?oaiio o?eiano?? i?ioeaio o?ainoi?iiaaieo ee?oei ca?eueoo(oueny ii??aiyii c oaeei i?e eaaeiio nooiaii ia 26, o o?aoueiio - aiaeiiaiaeii ia 8,4% ( ? < 0,05 ). I?e oyaeeiio nooiai? aiai?? i?ie?oa?aoeaia aeoeai?noue aeua, i?ae i?e eaaeiio, o ae?oaiio o?eiano?? ia 26 oa a o?aoueiio - ia 11,5% ( ? < 0,05 ). Oaeei /eiii, CAeA aaa?oieo noi?iaiaeaeo?oueny i?aeneeaiiyi a?aeiia?ae? ia OAA noeioeyoe?th, yea aeinoia??ii c?inoa? ?c c?inoaiiyi oyaeeino? CAeA. ?noioi? ci?ie i?e oeueiio oa?ieoue ?iaeaen i?a?aoe?? eaeeioeeo?a o ?AIE, iieacieee yeiai a aeeiai?oe? aaa?oiino? iinooiiai cieaeothoueny. Oae, i?e CAeA eaaeiai nooiaiy iieacieee ia e?iaoeue aaa?oiino? ii??aiyii c oaeeie o ia?oiio o?eiano?i ciaioothoueny ia 10,5% ( ? < 0,05 ). O aaa?oieo ?c CAeA na?aaeiueiai oa oyaeeiai nooiaiy iieacieee ?AIE ua a?eueoa cieaeai?: o ae?oaiio o?eiano?? ii??aiyii c oaeeie i?e aiai?? eaaeiai nooiaiy, a?aeiia?aeii, ia 45,9 ? 45,7% ( ? < 0,001 ), o o?aoueiio - ia 63,4 ? 58,1% ( ? < 0,001 ). Ioaea, o aaa?oieo ?c CAeA aeyaeai? iciaee iaoieia?? o ?icaeoeo ee?oeiii? nainea?e?caoe?? aei aioeaaia, ui na?ae/eoue i?i cieaeaiiy o ieo ooieoe?iiaeueii? aeoeaiino? O - ee?oeiii? eaiee ?ioi?oaoo. Ei?aeyoe?eiei aiae?cii anoaiiaeaii, ui i?ae ci?iaie cia/aiue ?AOE oa ?AIE ?niothoue iaai? e?i?ei? ca’ycee, i?e oeueiio ca?eueoaiiy oyaeeino? aiai?? ni?ey? ?inoo ?o neee: oae, i?e CAeA na?aaeiueiai nooiaiy o o?aoueiio o?eiano?? aeyaeaia aeinoia??ia cai?ioia iii?oia u?euei?noue ca’yceo ( r = - 0,62 ), i?e CAeA oyaeeiai nooiaiy - cai?ioiee aenieee nooi?iue u?eueiino? ca’yceo ( r = - 0,71 ). Oaeei /eiii, iaea?aeai? iaie aeai? i?i iaoieia?/i? ii?ooaiiy a oiae? ee?oeiii - ?ioiieo ?aaeoe?e o aaa?oieo ?c CAeA aeacothoue ia ?oith ?ieue o iaoai?ci? ci?ie ooieoe?iiaeueii? aeoeaiino? O - nenoaie ?ioi?oaoo a oe??? eaoaai??? oai?eo. O ae?iie ?c oneeaaeiaiith CAeA aaa?oi?noth iaeii/anii ?c ae?aaeaiei i?eai?/aiiyi O - nenoaie a?aeaoaa?oueny i?eai?/aiiy ? aoii?aeueii? eaiee ?ioi?oaoo: cieaeo?oueny aaniethoia e a?aeiinia /enei AAN - ?OE. Oae, ii??aiyii c iieacieeaie o caei?iaeo aaa?oieo, i?e eaaeiio nooiai? CAeA a?aeiinia e?eueeinoue AAN - ?OE o ae?oaiio oa o?aoueiio o?eiano?ao ciaioo(oueny ia 12,9 ? 25,1% ( ? < 0,05 ). I?e aiai?? na?aaeiueiai ? oyaeeiai nooiaiy o ae?oaiio o?eiano?? - ia 21,2 ? 29% ( ? < 0,05 ), o o?aoueiio - ia 32,7 ( ? < 0,05 ) oa 37,9% ( ? < 0,001 ). Ni?aa?aeiioaiiy A - ?OE oa AAN - ?OE o ae?oaiio oa o?aoueiio o?eiano?ao /a?ac iaio ae?aaeaiee aeao?oeeo A - ?OE ii??aiyii c AAN - ?OE aeaui ieae/a, i?ae ia e?iaoeue aaa?oiino?. A?aoiaoth/e, ui CAeA aaa?oieo noi?iaiaeaeo?oueny ae?aaeaiith a?ia?aeoeai?noth O - ee?oeiii? eaiee ?ioi?oaoo, ioneiaei iaoai?ciii i?eai?/aiiy A - nenoaie oa ?icaeoeo aaiiaanoico, eiiai?ii, iiaeia aaaaeaoe cieaeaiiy eiio?ieth c aieo ?ioii?aaoeyoi?ieo ee?oei noaiiioeyoe?e A - ?OE. Aioeo?eiooai?aiiy a i?aai?ci? aaa?oii? ae?iee ?c CAeA ye iieaciee ooieoe?iiaeueii? aeoeaiino? A - nenoaie ?ioi?oaoo noi?iaiaeaeo?oueny ae?aaeaiith ia?aaoaeiaith. Oae, yeui ??aaiue lg eeano A ia ci?ith?oueny i?ioyaii an??? aaa?oiino?, oi e?euee?noue lgM i?e aiai?? eaaeiai nooiaiy i?aeaeuaia ii??aiyii c oaeith o caei?iaeo aaa?oieo o ia?oiio o?eiano?? ia 7,4% ( ? < 0,05 ) ? o o?aoueiio - ia 28% ( ? < 0,001 ), lgG - i?aeaeuaii o aeeiai?oe? aaa?oiino?, a na?aaeiueiio, ia 27% (? < 0,001). ?c ?inoii oyaeeino? aiai?? a?aei?/aii i?aeaeuaiiy eiioeaio?aoe?? lgI oa lgG ii??aiyii c oaeei o caei?iaeo aaa?oieo i?e aiai?? na?aaeiueiai ? oyaeeiai nooiaiy o ae?oaiio o?eiano??, a?aeiia?aeii, ia 22,4 ? 41,4% ( ? < 0,001 ), o o?aoueiio - ia 33 ? 19,8% ( ? < 0,001 ). Ioaea, o aaa?oieo ?c CAeA ia oii? ?ioiiaeao?oeeoo AAN - ?OE a?aeaoaathoueny ae?aaeai? ci?ie o ooieoe?iioaaii? aoii?aeueii? eaiee ?ioi?oaoo, ui noi?iaiaeaeo?oueny ii?ooaiiyi ni?aa?aeiioaiiy iniiaieo eean?a lg, nooi?iue oeeo ii?ooaiue caeaaeeoue a?ae oyaeeino? aiai??. Eiiai?ii, i?aeaeuaiiy eiioeaio?aoe?? lgI oa lgG o aaa?oieo ?c CAeA iaoiiaeaia aioeaaiiith noeioeyoe??th i?aai?cio iaoa?? a ?acoeueoao? ii?oiooieoe?iiaeueieo ci?i o ieaoeaio? ( N.A. Aaa?ueyiiaa, 1988 ). A ?acoeueoao? ?ioiii? a?aeiia?ae? ia aioeaaiia noeioethaaiiy a i?aai?cii aaa?oii? ae?iee ooai?ththoueny ia eeoa AO, a e ?o eiiieaene ( A.ss. Eoeueaa?a, 1986 ), e?euee?noue yeeo i?e oneeaaeiai?e CAeA aaa?oiino?, ca iaoeie aeaieie, ?noioii c?inoa?. Ii??aiyii c oaeiaei o caei?iaeo aaa?oieo ai?no aaeeeeo Oe?E i?e aiai?? na?aaeiueiai nooiaiy oyaeeino? o ae?oaiio o?eiano?? ca?eueoaii ia 21% ( ? < 0,05 ), o o?aoueiio - ia 54% ( ? < 0,001 ), i?e aiai?? oyaeeiai nooiaiy, a?aeiia?aeii, ia 44,8% ( ? < 0,05 ) ? 76% ( ? < 0,001 ). ??aaiue iaeeo Oe?E o ae?oaiio ? o?aoueiio o?eiano?ao i?e CAeA na?aaeiueiai nooiaiy c?inoa? o 2,5 ? 2,8 ?ace, i?e oyaeeiio nooiai? - o 3 oa 3,2 ?ace. Ia iaoo aeoieo, ca?eueoaiiy Oe?E i?e CAeA aaa?oieo ? ?acoeueoaoii ii?ooaiiy ?ioiii? ?aaoeyoe?? a nenoai? AA - AO, ui i?iyaey?oueny i?aeaeuaiith aioeaaiiith noeioeyoe??th c aeoeaiei ca’ycoaaiiyi AA, ye? iaaeoiaeyoue o e?ia. Eiiai?ii, iiyaa iciae iaoieia?? a aoii?aeueieo ?aaeoe?yo nenoaie AA - AO o eiiieaen? iia’ycaieo i?ae niaith ?ioeo i?ioean?a a?ae?a?a? ?noioio ?ieue o iaoiaaiac? CAeA aaa?oieo, a, ioaea, o aeieeiaii? aaiiaanoico. Aaa?oi?noue, yea i?ioiaeeoue o?c?ieia?/ii, o a?aeiia?aeue ia iaaeoiaeaeaiiy a i?aai?ci iaoa?? AO ieiaea noi?iaiaeaeo?oueny aoii?aeueiith nainea?e?caoe??th ?c ooai?aiiyi aioeeaeeioeeoa?ieo AO oaea a ia?oiio o?eiano??. Ca ?acoeueoaoaie iaoeo aeine?aeaeaiue o caei?iaeo aaa?oieo /ano?oa aecia/a?oueny iaeei, ??aeoa - aeaa aeaee AO, aeey CAeA oa?aeoa?ia iiyaa a ne?iaaooe? e?ia? on?o o?ueio aeae?a AO ( e?ioioeeoioienei?a, eaeeiaaethoeiei?a, eaeeie?cei?a ). Iaea?eueoa e?euee?noue ?o aeyaeaia o ae?iie, o yeeo aoei 6 - 10 aaa?oiinoae, a oaeiae a aiaiiac? yeeo aoee aeeeaei?, ia?oaiia?iaeaeaiiy. Ia e?iaoeue aaa?oiino? e?euee?noue ?o ca?eueoaia o aeaa - o?e ?ace. *ano?oa aecia/a?ii e?ioioeeoioieneie, i?e oii, yeui i?e CAeA eaaeiai nooiaiy oeeoioiene/iee ?iaeaen o iaaeao 45 - 60%, oi i?e na?aaeiueiio ? oyaeeiio nooiaiyo o ae?oa?e iieiaei? aaa?oiino? a?i iai?oaeaiee, aeinyaa( 80% oa aeua. O 19 aaa?oieo c aiai??th na?aaeiueiai ? 10 - oyaeeiai nooiaiy aeyaeai? e?ioioeeoioieneie; o 2/3 ?c ieo a?aecia/aia iiceoeaia ?aaeoe?y eaeeiaaeathoeiaoe?? ( a?ae ++ aei ++++ ) c oeo?ii a?ae ( 1:2 ) aei ( 1:16 ). Eaeeie?ceie aecia/ai? iaeii/anii ?c e?ioioeeoioieneiaie a 42% i?e aiai?? na?aaeiueiai ? a 50% - oyaeeiai nooiaiy. Oaeei /eiii, ?acoeueoaoe iaoeo aeine?aeaeaiue na?ae/aoue i?i iayai?noue aoii?aeueii? nainea?e?caoe?? o aaa?oieo ?c CAeA ? i?aeoaa?aeaeothoue o/anoue aooi?ioiiiai eiiiiiaioo a ?? aoiieia?? oa iaoiaaiac?. I?ae /an aea/aiiy ieoaiiy ii?oieia?? ia?eoa?e/ii? e?ia? i?e oneeaaeiai?e CAeA aaa?oiino? iaie a?aecia/aii, ui oaea i?e aiai?? eaaeiai nooiaiy ia ii/aoeo aaa?oiino? i?inoaaeo?oueny cieaeaiiy e?eueeino? a?eo?ioeeo?a ia 14,3% ( ? < 0,05 ), aaiiaeiaiia ? aaiaoie?eoa, a?aeiia?aeii, ia 19,8% ( ? < 0,05 ) ? 18,4% ( ? < 0,05 ), ia aiaeiiio aiae oaeeo i?e oiciieiai/iie aaaioiinoi. I?e i?ia?anoaaiii aaa?oiino? a?aei?/aia iinooiiaa cieaeaiiy iieaciee?a a?eo?ioeeo?a ia 4,8, aaiiaeiaiio - ia 8,6, aaiaoie?eoo - ia 6,8% ( ? < 0,05 ). Na?aaeiie ei?ioneoey?iee ia’(i a?eo?ioeeoia ( MCV ) ? na?aaeiie aiino aaiiaeiaiio a a?eo?ioeeoi ( MCH ) o ii??aiyii? c oaeiaeie o caei?iaeo aaa?oieo o o?aoueiio o?eiano?? cieaeai? ia 12,1 ? 10,5%, na?aaeiy eiioeaio?aoeiy aaiiaeiaiio a e?iai ( ININ ) ia ci?ith(oueny. A?aecia/aii ??cieoeth eiaoioei(ioo aiicio?iii? a?eo?ioeeoia ( RDW ), yea aeinoia??ii ca?eueoo?oueny, ? ia e?iaoeue aaa?oiino? noaiiaeoue 22,6%. I?e aiai?? na?aaeiueiai ? oyaeeiai nooiaiy a?aeaoaathoueny ua a?eueoa ae?aaeai? ci?ie a ia?eoa?e/iie e?ia?. Oae, o e?ioe? aaa?oiino? o ii??aiyii? ?c caei?iaeie aaa?oieie a?aecia/aii cieaeaiiy e?eueeino? a?eo?ioeeo?a ia 18,8 ( ? < 0,05) ? 30,6% ( ? < 0,05 ), Hb - ia 22,5 ( ? < 0,05 ) ? 35,3% ( ? < 0,05 ), aaiaoie?eoo - ia 23,9 ( ? < 0,05 ) ? ia 30,9% ( ? < 0,05 ). Iieaciee INI i?e CAeA na?aaeiueiai ? oyaeeiai nooiaiy cieaeaiee ia 5,7 ( ? < 0,05 ) ? 8,2% ( ? < 0,05 ). MCV o ae?oaiio o?eiano?? i?e CAeA na?aaeiueiai ? oyaeeiai nooiaiy cieaeaiee ia 5,6 ( ? < 0,05 ) ? 2,4% ( ? > 0,05 ).

ININ i?e aiai?? na?aaeiueiai nooiaiy ?noioii ia ci?ith?oueny, i?e
oyaeeiio — cieaeaiee ia 8,3% ( ? < 0,05 ). A?aecia/aia ??cieoey RDW, yea aeinoia??ii ca?eueoo?oueny, ? ia e?iaoeue aaa?oiino? noaiiaeoue 23,7 oa 21,8%. Oaeei /eiii, ca ?acoeueoaoaie i?iaaaeaieo aeine?aeaeaiue, ?noeiii? CAeA ae?oai? iieiaeie aaa?oiino? ii?yae ?c cia/iei cieaeaiiyi ??aiy iniiaieo aaiaoieia?/ieo iieaciee?a ca ?aooiie a?ia?ieaci?? i?eoaiaiia cieaeaiiy ai?noo aaiiaeiaiio, ciaioaiiy ei?ioneoey?iiai ia’?io a?eo?ioeeo?a oa ca?eueoaiiy eiao?oe??ioa ai?cio?ii??. Ia iniia? aeuaaeeeaaeaiiai iiaeia i?eionoeoe, ui ci?ie o nenoai? aaiiiiaco, eiiai?ii, i?e/eiii - iane?aeeiai iia’ycai? c ii?ooaiiyie a ?ioiiiio aiiainoac? ? oea aea? i?aenoaae aaaaeaoe CAeA i?iyaeaiiyi aaiiaanoico ae?oai? iieiaeie aaa?oiino?. Anoaiiaeaii, ui ia oei CAeA ia?aaia aaaioiinoi i iieiaia iathoue iaaii iniaeeainoi. C oeei iia’ycaii eeiii/ii oa?aeoa?enoeee ia?aaiao aaaioiinoi, iieiaia i iineyiieiaiaiai ia?iiaeo o aeiiie, yei ia?aianee CAeA aaaioieo. Na?aae ieo, ca iaoeie aeaieie, /anoioa, iiae a iiioeyoei?, niinoa?iaa(oueny ?aiiie ( 15,2% ) oa iiciie ( 23,2% ) aanoice, caa?ica iaaeiiooaaiiy aaaioiinoi ( 34,3% ). Iacaaaeath/e ia oa, ui iieiae i iineyiieiaiaee ia?iiae i?ioiaeeee ia oiii eiiieaenii? oa?aii? i iie?auaiiy aaiaoieiai/ieo oa iioiieiai/ieo iieacieeia, aiie noi?iaiaeaeoaaeenue aaeeeith eieueeinoth oneeaaeiaiue. *anoioa iaoneeaaeiaieo iieiaia neeaea 26,9%; ia?aae/anii iieiae - 11,5%, aaaeiiiiaeueia ?ic?iaeaeaiiy - 21,1%, aeooa?nueei ueioei - 3,8%, e?iaioa/i o o?aoueiio oa ?aiiueiio iineyiieiaiaiio ia?iiaei - 25% oiui. Ia?eiaoaeueieo ao?ao aeioae i oyaeeeo iineyiieiaiaeo oneeaaeiaiue o aeiiie ia aoei. O ca’yceo c iaaeinoaoiueith aoaeoeai?noth ?nioth/iai o?aaeeoe?eiiai iaoiaeo e?eoaaiiy aaa?oieo ?c CAeA ( aei(oa, yea caaaa/aia aieeaie oa aioaiiiaie, i?aia?aoe 3 - io aaeaioiiai caeica o eiiieaeni c i?aaii/ieie eeneioaie, iieiaioaiiie, iie?iaeaiaioe ) iaie canoiniaaia a eiiieaen? c iei A?O. sse i?aaeei, i?ney 3 - 4 naain?a A?O iie?auo?oueny aiaoeo, i?eieiythoueny ioaeioa ? aethaaiiy, ii?iae?co?oueny nii, ciaioo?oueny caaaeueia neaae?noue. *a?ac 4 oeaei? a?ae ii/aoeo e?eoaaiiy cia/ii iie?auothoueny iieacieee aaiia?aie ii??aiyii ?c a?aeiia?aeieie iieacieeaie o oai?eo, ye? e?eoaaeeny o?aaeeoe?eiei iaoiaeii. Oae o aaa?oieo ?c CAeA na?aaeiueiai ? oyaeeiai nooiaiy a?aei?/aii caieueoaiiy e?eueeino? a?eo?ioeeo?a o o?aoueiio o?eiano??, a?aeiia?aeii, ia 3,4 ? 6% ( ? < 0,05 ), i?e oeueiio ??aaiue aaiiaeiaiio o oai?eo iniiaii? a?oie aeuee oaeiai a eiio?ieueiie ia 6,2 ? 5,2% ( ? < 0,05 ). A?aeiia?aeii ca?eueoo?oueny aaiaoie?eo iiae /an i?ia?anoaaiiy aaa?oiino? a na?aaeiueiio ia 1%, iacaeaaeii a?ae nooiaiy oyaeeinoi aiai??. O eaeeioeeoa?i?e oi?ioe? ??cieoey a cieaeaii? a?aeiiniiai neeaaeo e?ioioeeo?a o iniiai?e a?oi? ii??aiyii c oaeei o eiio?ieueiie neeaaea? a?ae 8,1 aei 3,6%; i?e oeueiio a?aei?/a?oueny a?eueoa ae?aaeaiee cnoa eaeeioeeoa?ii? oi?ioee ai?aai ca ?aooiie ca?eueoaiiy /enea naaiaioiyaea?ieo oa ciaioaiiy iaei/eiyaea?ieo iaeo?io?e?a o na?aaeiueiio ia 2,5 - 3,5%. ?noioii? ??cieoe? o ai?no? iiiioeeo?a, aiceiio?e?a oa aacio?e?a ia aeyaeaii. A?O ?noioii aieeaa? ia ci?io ?ioiiiai aiiainoaco aaa?oieo ?c CAeA. Oae, iaie iii?/ai? ci?ie o ai?no? a?aeiinii( ? aaniethoii? e?eueeino? AAN - ?OE, Aa - ?OE ? a ia?a?iciiae?e? ?ioiieo ee?oei. Iayai?noue AAN - ?OE o o?aoueiio o?eiano?? a iniiai?e a?oi? i?e aiai?? na?aaeiueiai oa oyaeeiai nooiaiy o ii??aiyii? c oaeei o eiio?ieueiie ca?eueoaia ia 15,4 oa 18,9% ( ? < 0,05 ). A?aei?/aia oaiaeaioe?y iacaeaaeii a?ae nooiaiy oyaeeino? aiai?? aei cieaeaiiy Aa - ?OE ( a?eueoa ae?aaeaia a iniiai?e a?oi? ) oa ciaioaiiyi oaeia?iiai ? ca?eueoaiiy noi?ani?iiai aieeao. Aiaeiinia e?euee?noue O( a iaio a?oiao oai?eo ?c CAeA eaaeiai nooiaiy ia( oaiaeaioeith aei cieaeaiiy, O( - caieueoothoueny. I?e CAeA na?aaeiueiai ? oyaeeiai nooiaiy eieueeinoue O( o o?aoueiio o?eiano?i iniiaii( a?oie o ii?iaiyiii c oaeith o eiio?ieueiie a?oii ciaioo(oueny ia 13,2 i 13,7% ( ? < 0,05 ), a ai?no O( ca?eueoai ia 22,1% i 7,4% ( ? < 0,05 ). Ioaea, cai?iiiiiaaia oa?aiiy c aeei?enoaiiyi A?O ni?ey? aeoea?caoe?? ?ioi?oaoo, ii?iae?caoe?? ?ioiieia?/ieo iieaciee?a ?, oei naiei, ? aoaeoeaiei caniaii aieeao ia cieaeaiiy iaoa?einueei? ?ioiii? a?aeiia?ae? ia ie?ae. Ia iaoo aeoieo, A?O, ?noioii aieeaath/e ia ooieoe?iiaeueio aeoeai?noue O - nenoaie ?ioi?oaoo, ii?iae?co? o?ae ee?oeiieo ?ioiieo ?aaeoe?e. Oae, o oai?eo ia CAeA na?aaeiueiai oa oyaeeiai nooiaiy iniiaii? a?oie iieacieee ?AIE o o?aoueiio o?eiano?? iiaeaeuothoueny, a?aeiia?aeii ia 45,9 ? 38,8% ( ? < 0,05 ), ?AOE - cieaeai? ia 19,8 ? 39,3% ( ? < 0,05 ). Ciiith(oueny oaeiae noai aoii?aeueii? eaiee ?ioi?oaoo. Anoaiiaeaii, ui i?ae aieeaii e?eoaaiiy aeinoia??ii cieaeo?oueny ai?no ne?iaaoeiaeo lgI i lgG. I?e oeueiio ??cieoey iieaciee?a ??aiy lgI i?e CAeA na?aaeiueiai ? oyaeeiai nooiaiy o o?aoueiio o?eiano?? iniiaii? a?oie o ii??aiyii? c oaeeie o eiio?ieueiie neeaaea? 15 ? 7,8% ( ? < 0,05 ), lgG - 9,6 ? 11,3% ( ? < 0,05 ). Oaeei /eiii, iaea?aeai? aeai? aeacothoue ia ?ioii?aaoethth/ee aieea cai?iiiiiaaii( oa?aii(, ui ni?ey( cieaeaiith ?ioiii? a?aeiia?ae? iaoa?einueeiai i?aai?cio ia ie?ae o nenoai? AA - AO ?, oei naiei, ii?iae?caoe?? ooieoe?? aoii?aeueii? eaiee ?ioi?oaoo. Acaaae?, i?e aeeth/aii? A?O a eiiieaen e?eoaaiiy aaa?oieo ?c CAeA aeyaeai? ?noioi? iiceoeaii ciiie a ae?yeueiino? ee?oeiii - aoii?aeueiiai ?ioi?oaoo, ui i?aeaeuo( ?ioiieia?/io ?aaeoeai?noue i?aai?cio, ?, oei naiei, ni?ey( ii?iae?caoe?? iaoieia?/ieo a?aeoeeaiue ye o ee?oeii?e, oae ? aoii?aeuei?e eaieao ?ioi?oaoo, i?e oeueiio iie?auothoueny aaiiiiaoe/i? oaeoi?e ia?eoa?e/ii? e?ia?. O aeiiie, yei eieoaaeenue A?O a eiiieaeni aioeaiaii/ii? oa?aii? ia aoei ia?aae/anieo iieiaia, ciaioeeanue /anoioa aaaeiiiiaeueiiai ?ic?iaeaeaiiy aei 12%, e?iaioa/ o o?aoueiio oa ?aiiueiio iineyiieiaiaiio ia?iiaei - aei 4%, iineyiieiaiaeo oneeaaeiaiue - aei 4%. Ani aeioe ia?iaeeeeny aeeaeie c ioeiieith ii oeaei Apgar 7 - 8 aaeia. Ia?iiae ?aiiuei( iineyiieiaiai( aaeaioaoei( ia?aaiaaa aac oneeaaeiaiue. AENIIAEE 1. O?c?ieia?/ia aaa?oiinoue noi?iaiaeaeo(oueny oieiaaiaoe/ii iaoiiaeaiei /anoeiaei i?e?iaeiei ?ioiiaeao?oeeoii O ( A - ?OE ) - ? A ( AAN - ?OE ) - eiioioeeoia ye aaeaioaoe?eii - i?enoinoaaeueiei iaoai?ciii caaacia/aiiy ?ioiieia?/ii( oiea?aioiinoi. I?e CAeA aaaioieo ia oii? ?ioiiaeao?oeeoo A - ?OE ? i?aeneeaiiy aeao?oeeoo AAN - ?OE ?icaeaa?oueny oaeiae ?ioiiaeao?oeeo Aa - ?OE. Oea na?ae/eoue i?i a?ii?aaeoeai?noue ?ioi?oaoo o aaa?oieo ?c CAeA oa iiaeeeao o/anoue ?ioiieia?/ieo eiiiiiaio?a o ?? iaoiaaiac?. 2. Aeey aaaioiinoi c ii?iaeueiei ia?aaiaii, ii/eiath/e c ia?oiai o?eiano?o, oa?aeoa?ia cieaeaiiy O( - oaeia?ia oa caieueoaiiy O( - coi?ani?ia; i?e CAeA ?icaeaa(oueny aeeni?iii?oeiy noaiiioeyoeie O - nenoaie c iiaeneeaiiyi oaeia?iiai oa aeaoioeeoii noi?ani?iiai aieeao; ia( iinoea inoeiia caieueoaiiy ?iaiae IgM oa IgG, aaeeeeo oa iaeeo OeIE, ui naiae/eoue i?i inoioii ii?ooaiiy iioiii( ?aaoeyoei( o nenoaii aioeaai - aioeoiei; ?icaeaa(oueny aoii?aeueia naineaieicaoeiy c ooai?aiiyi aioeeaeeioeeoa?ieo aioeoie: eiioioeeoioieneiia, ?iaeoa eaeeieiceiia, ui naiae/eoue i?i o/anoue aooiiioiiiai eiiiiiaioo a iaoiaaiaci i?e?iaeiuei( CAeA. Aeeaeia aeyaeaieo ciii i?iii?oeieia oyaeeinoi aiaii(. 3. A ?acoeueoaoi i?eaii/aiiy ooieoeiiiaeueii? aeoeaiinoi O - i A - nenoai iioiioaoo i?e CAeA aaaioieo c’yaeythoueny iaoieiai/ii ciiie ia?aaiao eeioeiii - iioiieo ?aaeoeie, iniaeeai, a nenoaii aioeaai - aioeoiei: iiaeneeaiiy aiaeiiaiaei ia OAA noeioeyoeith a ?AOE oa cieaeaiiy iieacieeia ?AIE. 4. Inoeiia CAeA aaa?oieo ii?yae ?c ci?iith iniiaieo iieaciee?a aaiia?aie ( eieueeinoue a?eo?ioeeoia, ?aoeeoeioeeoia, aaiiaeiaiio; aaiaoie?eo ), oa?aeoa?eco(oueny icoioii aiaeiiiiith ii?oieia?/iith oa?aeoa?enoeeith a?eo?ioeeo?a ( ciaioaiiy na?aaeiueiai aiinoo aaiiaeiaiio a a?eo?ioeeoi, ca?aaeiueiai ei?ioneoey?iiai ia’(io a?eo?ioeeoia, a oaeiae ca?eueoaiiy eiaoioei(ioo aiicio?iii( ). 5. I?e CAeA aaaioieo ciiie a nenoaii aaiiiiaco, eiiieaen e?euee?nieo ? ye?nieo ci?i a ?ioiieia?/iiio aiiainoac?, ui aeoiaeyoue ca iaae? o?c?ieia?/ieo, i/aaeaeii, ? ioneiaei iaoai?ciii ?icaeoeo ee?i?ei - ?ioiiiaoieia?/iiai noaio, yeee iiaea aooe iacaaiee ye aaiiaanoic aaa?oieo. 6. Eiiieaenia oa?aiiy ic canoinoaaiiyi A?O ( aoaeoeaiei iaoiaeii e?eoaaiiy aiaii? caaaeyee ia oieueee aaiinoeioethth/i(, aea e iioiiiiaeoethth/i( aei(. Canoinoaaiiy ?aeiiaiaeiaaii( oa?aii( ni?ey( aeiiooaaiith aaaioiinoi aei oa?iiio iieiaia, ciaioaiith /anoioe iia?aoeaiiai ?ic?iaeaeaiiy, oneeaaeiaiue iiae /an aaaioiinoi, iieiaia oa iineyiieiaiaiai ia?iiaeo, a oaeiae o iiaiia?iaeaeaieo. Aiia iiaea aooe ?aeiiaiaeiaaia aei oe?ieiai ai?iaaaeaeaiiy a aeooa?nueeo i?aeoeeo. NIENIE IIOAEIEIAAIEO ?IAIO CA OAIITH AeENA?OAOeI( 1. I ninoiyiee O - nenoaie eiioieoaoa i?e ii?iaeueii i?ioaeathuae e ineiaeiaiiie aeaeaciaeaoeoeeoiie aiaiee aa?aiaiiinoe // iaaeeei-nioeeaeueiua i?iaeaiu naiuee. - 1997. - O.2, ?1. - N. 15 - 18 ( a niaao. n Eaooai N.N. ). 2. Ia iniaaiiinoyo eiioiiiai noaoona aa?aiaiiuo aeaiuei n aeaeaciaeaoeoeeoiie aiaieae iinea eiiieaeniiai ea/aiey n i?eiaiaieai eaei?aoeaenioa?aiee // A?a/aa. aeaei. - 1997. - N. 103 - 107. 3. Aoii?aeueiue eiioieoao o aeaiuei i?e ii?iaeueii i?ioaeathuae e ineiaeiaiiie aeaeaciaeaoeoeeoiie aiaieae aa?aiaiiinoe // A?a/aa. aeaei. - 1997. - ?4. - N. 107 - 110 ( a niaao. n Eaooai N.N. ). 4. Aeeiaieea iieacaoaeae ia?eoa?e/aneie e?iae o aeaiuei a?oiiu ?enea aiaiee a oa/aiea aa?aiaiiinoe // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ii cae?i/aieo oa ia?ao?aeieo IAe? ca 1990 - 1996 ?iee: Ee?a, 1997. - N. 669 - 673. 5. I aoii?aeueiie naineaeeecaoeee o aeaiuei n ii?iaeueii i?ioaeathuae e ineiaeiaiiie aeaeaciaeaoeoeeoiie aiaieae aa?aiaiiinoueth // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ii cae?i/aieo oa ia?ao?aeieo IAe? ca 1990 - 1996 ?iee: Ee?a, 1997. - N. 674 - 677. 6. “ I?eiaiaiea iaoiaea eaei?aoeaenioa?aiee a eiiieaeniii ea/aiee aiaiee aa?aiaiiuo “ ( ?aoe?iiae?caoi?nueea i?iiiceoe?y ?5 a?ae 17 ea?oiy 1997 ?., caoaa?aeaeaia Aiaeaeieii iaoeiai( i?aaiicaoei( i?aoei i?e noaoenoe/iiio aiaeaeiei Aieiaiiai oi?aaeiiiy ICC ). AIIOAOe?ss Oooi?iee N.I. Noai ?ioiii? nenoaie ? iniaeeaino? ii?oieia?? ia?eoa?e/ii? e?ia? i?e cae?ciaeao?oeeoi?e aiai?? aaa?oieo. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ii niaoe?aeueiino? 14. 01. 01 - aeooa?noai ? a?iaeieia?y. Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe IIC Oe?a?ie, Ee?a, 1998 ?. Caoeua(oueny aeena?oaoeieia ?iaioa i?i iniaeeaino? ?ioi?oaoo oa ii?oieia?th e?ia? i?e ii?iaeueiiio ia?aaiao aaaioiinoi i aaa?oiinoi, ui oneeaaeiaia cae?ciaeao?oeeoiith aiai??th; canoinoaaiiy aieei?aoeaenioa?aii? o eiiieaeniiio eieoaaiii CAeA aaaioieo. Ia aiaeiiio a?ae caei?iaeo aaa?oieo o aaa?oieo c CAeA aeyaeai?: a?eueoa ae?aaeaia a?ii?aaeoeai?noue ee?oeiiiai ?ioi?oaoo, iciaee iaoieia?? a ni?aa?aeiioaii? ?aaoeyoi?ieo O - ee?oeiieo noaiiioeyoe?e oa ia?aaiao ee?oeiii - ?ioiieo ?aaeoe?e. Ia oii? ?ioiiaeao?oeeoo A - nenoaie ?icaeaa?oueny ii?ooaiiy ni?aa?aeiioaiiy iniiaieo eean?a ?ioiiaeiaoe?i?a oa ?aaoeyoe?? a nenoai? aioeaai - aioeo?ei. Cai?iiiiiaaia iaoiaaiaoe/ia eiioeaioe?y CAeA aaa?oieo ye ee?i?ei -?ioiiiaoieia?/iiai noaio - aaiiaanoico aaa?oieo. Aeeth/aiiy aieei?aoeaenioa?aii? o eiiieaenia e?eoaaiiy CAeA aaa?oieo i?aeaeuo? ?ioiieia?/io ?aaeoeai?noue, ii?iae?coth/e iaoieia?/i? a?aeoeeaiiy ye o ee?oeii?e, oae ? aoii?aeuei?e eaieao ?ioi?oaoo, iie?auo? aaiiiiaoe/i? oaeoi?e ia?eoa?e/ii? e?ia? oai?eo, iieiioo( eeiii/iee ia?aaia aaaioiinoi, iieiaia i iineyiieiaiaiai ia?iiaeo. Eeth/ia? neiaa: aaa?oi?noue, cae?ciaeao?oeeoia aiai?y, aieei?aoeaenioa?ai?y, ee?oeiiee ? aoii?aeueiee ?ioi?oao, ?ioiieia?/ia ?aaeoeai?noue, aaiiaanoic aaa?oieo. AIIIOAOeEss Oooi?iue N.I. Ninoiyiea eiioiiie nenoaiu e iniaaiiinoe ii?oieiaee ia?eoa?e/aneie e?iae i?e aeaeaciaeaoeoeeoiie aiaiee aa?aiaiiuo. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14. 01. 01 - aeooa?noai e aeiaeieiaey. Eeaaneay iaaeeoeeineay aeaaeaiey iineaaeeieiiiiai ia?aciaaiey IC Oe?aeiu, Eeaa, 1998 a. Caueuaaony aeenna?oaoeeiiiay ?aaioa ia iniaaiiinoyo eiioieoaoa e ii?oieiaee ia?eoa?e/aneie e?iae i?e ii?iaeueii i?ioaeathuae e ineiaeiaiiie aeaeaciaeaoeoeeoiie aiaieae ( AEAeA ) aa?aiaiiinoe; eniieueciaaiea eaei?aoeaenioa?aiee a eiiieaeniii ea/aiee AEAeA aa?aiaiiuo. A ioee/ea io caei?iauo aa?aiaiiuo o aa?aiaiiuo n AEAeA onoaiiaeaiu: aieaa au?aaeaiiay aeii?aaeoeaiinoue eeaoi/iiai eiioieoaoa, i?eciaee iaoieiaee a niioiioaiee ?aaoeyoi?iuo O - eeaoi/iuo noaiiioeyoeee e oa/aiee eeaoi/ii - eiioiiuo ?aaeoeee. Ia oiia eiioiiaeaoeoeeoa A - neoaiu ?acaeaaaony ia?ooaiea niioiioaiey iniiaiuo eeannia eiioiiaeiaoeeiia e ?aaoeyoeee a nenoaia aioeaai - aioeoaei. I?aaeeiaeaia iaoiaaiaoe/aneay eiioeaioeey AEAeA aa?aiaiiuo eae eeeieei - eiioiiiaoieiae/aneiai ninoiyiey - aaiiaanoica aa?aiaiiuo. Aeeth/aiea eaei?aoeaenioa?aiee a eiiieaeniia ea/aiea AEAeA aa?aiaiiuo iiauoaao eiioiieiae/aneoth ?aaeoeaiinoue, ii?iaeecoy iaoieiae/aneea ioeeiiaiey eae a eeaoi/iii, oae e aoii?aeueiii caaiueyo eiioieoaoa, oeo/oaao aaiiiiyoe/aneea oaeoi?u ia?eoa?e/aneie e?iae aieueiuo, eeeie/aneia oa/aiea aa?aiaiiinoe, ?iaeia e iinea?iaeiaiai ia?eiaea. Eeth/aaua neiaa: aa?aiaiiinoue, aeaeaciaeaoeoeeoiay aiaiey, eaei?aoeaenioa?aiey, eeaoi/iue e aoii?aeueiue eiioieoao, eiioiieiae/aneay ?aaeoeaiinoue, aaiiaanoic aa?aiaiiuo. SUMMARY Futorny S.M. State of immune system and peculiarities of morphology of peripheric blood in iron deficiency anemia of pregnant women. - Manuscript. This is for an academic degree of a candidate of medical sciences in speciality 14. 01. 01 - Obstetrics and gynecology. The Kyiv Medical Academy of post - diploma education of the Ministry of Health Protection of Ukraine, Kyiv, 1998. There is defended scientific work on peculiarities of immunity and morphology of peripheric blood in normal and complicated course of pregnancy iron deficiency anemia ( IDA ); use of acupuncture and reflexotherapy in a complex treatment of iron deficiency anemia in pregnant women. The results of the researches of the immune status in the course of uncomplicated pregnancy have shown that in case of pregnancy and its progressing in mother’s organism there occurs a reduction of the activity of T -immune system, and this is confirmed by the revealed changes in the composition of its regulatory subpopulations and in the course of cellular -immune reactions, as well as reduction of the activity of humoral immunity. Natural partial immune deficiency of the T - and B - immune systems, which takes shape in the process of a physiologically proceeding pregnancy, is of a protective - adaptive character and ensures its immunotolerance in respect to fetus. In comparison with healthy pregnant women, pregnant women with iron deficiency anemia are found to have more pronounced hyporeactivity of cellular immunity; these changes are regarded as the obvious signs of pathology. These data are supplemented with considerable changes, revealed in the regulation of immune response at the expense of the developing disproportion of imminoregulatory cells with increase of helper effect and deficiency of suppressible influence of T - immune system, as well as in the reduction of its functional activity, causally related to the changes in cellular - immune reactions. On the background of immunodeficiency of B - system there develops a disturbance in the correlation of the main classes of immunoglobulin and regulation in the system “ antigen - antibody “. Proposed a pathogenetic concept of pregnant women’s IDA as a clinical - immunopathological state - pregnant women’s hemogestosis. Such concept opens new approaches and prospects for search of pathogenetic methods of treatment of iron deficiency anemia in pregnant women. The carried out analysis of examination of hemogram indices in pregnant women with iron deficiency anemia proves, that apart from lowering of the levels of the main hematologic indices, verus iron deficiency anemia during the second half of pregnancy is characterized by reduction of hemoglobin content in erythrocytes, reduction of their corpuscular volume and increase of the coefficient of erythrocytes’ anisotropy. Inclusion of acupuncture and reflexotherapy in a complex treatment of pregnant women’s IDA increases the immune reactivity, normalizing pathological deviations both in cellular and humoral links of immunity, improving hemopoietic factors of the patients’ peripheric blood, clinical current of pregnancy, birth and postbirth period. The efficiency of acupuncture and reflexotherapy, having an immonomodulating effect in treatment of iron deficiency anemia in pregnant women, normalization of immunologic indices, side by side with positive changes in hemogram, is a weighty evidence of correctness of the advanced pathogenetic concept of iron deficiency anemia in pregnant women as hemogestosis. Key words: pregnancy, iron deficiency anemia, acupuncture and reflexotherapy, cellular and humoral immunity, immunologic reactivity, hemogestosis of pregnant women.

Похожие записи