I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

EE?ANUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO

AI?AeAI?IEIA?? OA ?IOAEOe?EIEO OAI?IA

?i. E.A. A?IIAOAANUeEIAI

OAeE
616.98-078+578.826.6:351.774.

NA?AA?AA OAOssIA AIAOIE??AIA

NIAOeEO?*IA ?IOIIAe?AAIINOEEA A NENOAI? AI?AeAI?IEIA?*IIAI

IAAEssAeO CA A?E-?IOAEOe??TH

14.02.02 — ai?aeai?ieia?y

A a o i ? a o a ? a o

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Ee?anueeiio iaoeiai-aeine?aeiiio ?inoeooo?
ai?aeai?ieia??

oa ?ioaeoe?eieo oai?ia ?i. E.A. A?iiaoaanueeiai
IIC Oe?a?ie

Iaoeia? ea??aieee:

aeieoi? iaaee/ieo iaoe, i?ioani?, caneoaeaiee ae?y/ iaoee oa
oaoi?ee

Oe?a?ie A.I. Ca?eoeueeee, Ee?anueeee iaoeiai-aeine?aeiee ?inoeooo
ai?aeai?ieia?? oa

?ioaeoe?eieo oai?ia, caa?aeoaa/ eaai?aoi???th ai?aeai?ieia?? ?
i?io?eaeoeee

eeoeiaeo ?ioaeoe?e

eaiaeeaeao iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee ?.E.
Ia?e/aa,

Ee?anueeee iaoeiai-aeine?aeiee ?inoeooo ai?aeai?ieia?? oa
?ioaeoe?eieo oai?ia,

caa?aeoaa/ eaai?aoi???th ?ioiieia??

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, /eai-ei?aniiiaeaio Oe?a?inueei? aeaaeai??
aeieia?/ieo iaoe, i?ioani? A.?. Oaaei?ia, Oa?e?anueeee ?inoeooo
oaeineiiaeaiiy e?ea??a, caa?aeoaa/ eaoaae?ith ai?aeai?ieia?? ?
iaaee/ii? ia?aceoieia??

aeieoi? iaaee/ieo iaoe, /eai-ei?aniiiaeaio AII Oe?a?ie, i?ioani?

?.O. *a?iooaiei, Ee?anueeee ?inoeooo ooec?ao??? oa ioeueiiiieia??,
caa?aeoaa/

eaai?aoi???th ?ioiieia??

I?ia?aeia i?aai?caoe?y:

Iaoe?iiaeueiee iaaee/iee Oi?aa?neoao ?i. I.I. Aiaiiieueoey, i. Ee?a

Caoeno a?aeaoaeaoueny “ 29 “ a?oaeiy 1998
?ieo i 11 aiaeei?

ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae – 26.614.02 ii caoenoo
aeieoi?nueeeo aeena?oaoe?e i?e Ee?anueeiio iaoeiai-aeine?aeiiio
?inoeooo? ai?aeai?ieia?? oa ?ioaeoe?eieo oai?ia ?i. E.A. A?iiaoaanueeiai
IIC Oe?a?ie ( 252038, i. Ee?a, oca?c I?ioan?a ss?, 4 )

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Ee?anueeiai
iaoeiai-aeine?aeiiai

?inoeoooa ai?aeai?ieia?? oa ?ioaeoe?eieo oai?ia ?i. E.A.
A?iiaoaanueeiai IIC Oe?a?ie

( 252038, i. Ee?a, oca?c I?ioan?a ss?, 4 )

Aaoi?aoa?ao ?ic?neaiee “ 29 “ eenoiiaaea 1998 ?.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe E.N. E?anthe

Aeooaeuei?noue ?iaioe

A oaia??oi?e /an A?E-?ioaeoe?y/NI?Ae iaaoea cia/aiiy iaei??? c iniiaieo
i?iaeai ioi?iie caei?ia’y a onueiio na?o?. Oea iia’ycaii c oe?ieei,
iianthaeiei ?iciianthaeaeaiiyi ?ioaeoe??, iaooeeueiei c?inoaiiyi /enea
A?E-?io?eiaaieo, aeeeth/ii oyaeeei ia?aa?aii caoai?thaaiiy, o?aaeaiiyi,
aieiaiei /eiii, i?aoeacaeaoiiai ianaeaiiy a iaea?eueo ?ai?iaeoeoeaiiio
a?oe?, aaeeeeie aeiiii?/ieie aeo?aoaie oa ?ioeie oaeoi?aie, ui
oa?aeoa?ecothoue aenieo nioe?aeueio cia/ou?noue aeaii? iaoieia??.

A Oe?a?i? A?E-?ioaeoe?th ii/aee aea/aoe ? ?a?no?oaaoe o 1987 ?., ? ia
e?iaoeue ?-? /aa?o? 1998 ?. aoei ca?a?no?iaaii 33539 aeiaaee?a
A?E-?ioaeoe??, a oiio /ene? 33275 na?aae a?iiaaeyi Oe?a?ie ? 264 na?aae
?iicaioe?a. Ca ieioea aeanyoe??//y a ai?aeai?/iee i?ioean iinooiiai
ooyaoaaeeny ana iia? iaeano? Oe?a?ie, ??ci? aa?noae ianaeaiiy oa a?eia?
a?oie, ? ia nueiaiaei?oi?e aeaiue aeiaaeee A?E-?ioaeoe?? a?aei?/ai? ia
on?o aaei?i?no?aoeaieo oa?eoi??yo.

A?E-?ioaeoe?th ne?ae a?aeiineoe aei iaea?iaaieo ?ioaeoe?e. Oiio
ni?yiiaai?noue iniiaieo caoiae?a, ui ni?eythoue iaiaaeaiith
?iciianthaeaeaiiy ?ioaeoe??, iiaeiia aooe ci???ioiaaiith ia
iiia?aaeaeaiiy ca?aaeaiiy a??onii, ciaioaiiy iaaaoeaiiai aieeao
A?E-?ioaeoe?? ia noni?euenoai. Oae? caoiaee iiaeooue aooe caaacia/ai?
eeoa caaaeyee aeia?a iaeaaiaeaeai?e nenoai? ai?aeai?ieia?/iiai iaaeyaeo
(AI). Iniiaiiieiaeiith eaieith AI ? aacia?a?aii ooieoe?iioth/a nenoaia
noaaeaiiy ca ai?aeai?/iith ianoaiiaeith, ui iaiiaeeeai aac canoinoaaiiy
no/anieo iaoiae?a eaai?aoi?ii? ae?aaiinoeee. Aiae?c ?acoeueoao?a
eaai?aoi?ieo aeine?aeaeaiue, ie??i ae?aaiinoeee A?E-?ioaeoe??, ia?
aaaeeeaa cia/aiiy aeey aecia/aiiy nooiaith ?iciianthaeaeaiiy ?ioaeoe?? ?
noai?th? iniiao aeey ieaioaaiiy, i?iaaaeaiiy ? ioe?iee ?acoeueoao?a
i?io?eaeoe/ieo ? i?ioeai?aeai?/ieo caoiae?a.

Oaeei /eiii, no/ani? niaoeeo?/i? eaai?aoi?i? aeine?aeaeaiiy ? nooo?aith
ia?aaeoiiaith aoaeoeaiiai ooieoe?iioaaiiy AI ca A?E-?ioaeoe??th ?
yaeythoue niaith iaa?ae’?iio neeaaeiao /anoeio ?ioi?iaoe?eiiai
caaacia/aiiy nenoaie AI. Ioaea ia?niaeoeae i?aeaeuaiiy aoaeoeaiino? AI
ca A?E-?ioaeoe??th a cia/iiio nooiai? iia’ycai? c ?ic?iaeith oa
ai?iaaaeaeaiiyi no/anieo iaoiae?a eaai?aoi?ii? ae?aaiinoeee, aecia/aiiyi
no?aoaa?? ? oaeoeee ?o canoinoaaiiy a caeaaeiino? a?ae eiie?aoii?
ai?aeai?/ii? neooaoe??.

Iaoa ?iaioe iieyaaea o ?ic?iaoe? no?aoaa?? ? oaeoeee niaoeeo?/ii?
?ioiiae?aaiinoeee a nenoai? ai?aeai?ieia?/iiai iaaeyaeo ca
A?E-?ioaeoe??th.

Aeey ?aae?caoe?? aeacaii? iaoe ae??ooaaeeny oae? caaaeaiiy:

1. Aecia/eoe ?ioi?iaoeai?noue oano-nenoaie «?OA-A?E 1/2» (/ooeea?noue,
niaoeeo?/i?noue, a?aeoai?thaai?noue) i?e ianoaaeaii? ??cieo eiioeiaaio?a
ianaeaiiy.

2. Ia i?aenoaa? iaoaiaoe/iiai iiaeaethaaiiy ?ic?iaeoe i?aeoiaee aei
aeai?o no?aoaa?? niaoeeo?/ieo eaai?aoi?ieo ianoaaeaiue ia
A?E-?ioaeoe?th.

3. Ioe?ieoe aoaeoeai?noue ?nioth/eo no?aoaa?e ?ioiiae?aaiinoeee
A?E-?ioaeoe?? c iaoith oaeineiiaeaiiy na?iai?aeai?ieia?/iiai iaaeyaeo.

4. ?ic?iaeoe ?aeiiaiaeaoe?? ii aeai?o ae?aaiinoe/ieo oano-nenoai ?
no?aoaa?e na?ieia?/ieo aeine?aeaeaiue ??cieo eiioeiaaio?a ianaeaiiy
Oe?a?ie a caeaaeiino? a?ae ?iciianthaeaeaiino? ?ioaeoe?? ? iaoe
oanooaaiiy.

5. Aaeineiiaeeoe ?ioi?iaoe?eio i?aenenoaio ai?aeai?ieia?/iiai iaaeyaeo
ca A?E-?ioaeoe??th a Oe?a?i?.

Iaoeiaa iiaecia aeine?aeaeaiue

Aia?oa a Oe?a?i? ae?aaiinoe/i? oa?aeoa?enoeee iaoiae?a ?ioiioa?iaioiiai
aeyaeaiiy aioeo?e aei A?E aena?oeai? c iiceoe?? oai??? ne?ei?iao.
I?iaaaeaia ii??aiyeueia ioe?iea aoaeoeaiino? canoinoaaiiy ?nioth/eo
no?aoaa?e ?ioiiae?aaiinoeee A?E-?ioaeoe?? i?e ianoaaeaii? ??cieo a?oi
ianaeaiiy a caeaaeiino? a?ae ?ioaineaiino? ai?aeai?/iiai i?ioeano ? iaoe
ianoaaeaiiy.

Ia iniia? oai?aoe/ieo eiioeaioe?e i?i /ooeea?noue, niaoeeo?/i?noue
?ioiiae?aaiinoe/ieo i?aia?ao?a, ?oiuei? i?iaiicoth/i? caeaoiino?
iieacaii i?ia?aeia cia/aiiy eaai?aoi?ii? ae?aaiinoeee a ?ioi?iaoe?eiiio
caaacia/aii? ai?aeai?ieia?/iiai iaaeyaeo ca A?E-?ioaeoe??th.

Iaoeiai iaa?oioiaaia no?oeoo?a ?ioi?iaoe?eii? i?aenenoaie oa ?? ?ieue a
ai?aeai?ieia?/iiio iaaeyae? ca A?E-?ioaeoe??th.

I?aeoe/ia cia/aiiy ?iaioe

Ia iniia? eiiieaeniiai aea/aiiy ae?aaiinoe/ieo oa?aeoa?enoee ia?oi?
a?o/eciyii? oano-nenoaie aeey aeyaeaiiy aioeo?e aei A?E «?OA-A?E 1/2»
anoaiiaeaia iiaeeea?noue ?? aeei?enoaiiy aeey i?iaaaeaiiy ianoaaeaiue
??cieo eiioeiaaio?a ianaeaiiy Oe?a?ie. Oano-nenoaia «?OA-A?E 1/2»
ai?iaaaeaeaia a i?aeoeeo eaai?aoi?ii? ae?aaiinoeee 22 iaeanoae Oe?a?ie,
i?no Ee?aa ? Naaanoiiiey.

?ic?iaeai? ?aeiiaiaeaoe?? ii aeai?o ae?aaiinoe/ieo oano-nenoai ?
no?aoaa?? niaoeeo?/ii? ?ioiiae?aaiinoeee A?E-?ioaeoe??. Iieacaii, ui
aeey ?ioi?iaoe?eiiai caaacia/aiiy AI ca A?E-?ioaeoe??th iaiao?aeiee
aeeoa?aioe?eiaaiee i?aeo?ae aei eaai?aoi?ieo aeine?aeaeaiue, a
caeaaeiino? a?ae iaoe ianoaaeaiiy, eiioeiaaio?a, a oaeiae a?ae ??aiy
?iciianthaeaeaiiy ?ioaeoe??. I?aeaioiaeai? iaoa??aee aeey
?ioi?iaoe?eiiai atheaoaiy «A?E-?ioaeoe?y a Oe?a?i?».

?ic?iaeaia oa caoaa?aeaeaia a Oa?iaeiiaeiiio Eii?oao? IIC Oe?a?ie
Oei/aniaa oa?iaeiiaeia noaooy «Oano-nenoaia ?ioiioa?iaioia aeey
aeyaeaiiy aioeo?e aei a??ono ?ioiiaeao?oeeoo ia?oiai ? ae?oaiai oei?a
«?OA-A?E 1/2» (OON 42O-200/121-264-96). Io?eiaiee Iaoaio Oe?a?ie ia
aeiao?ae «Niin?a

aeey aeyaeaiiy aioeo?e o ethaeeie i?ioe a??ono ?ioiiaeao?oeeoo ethaeeie
ia?oiai ? ae?oaiai oei?a /oano-nenoaia «?OA-A?E 1/2» (?14501 A
09.01.97).

Iniiai? iieiaeaiiy, ui aeiinyoueny ia caoeno

1. Aecia/aiiy ae?aaiinoe/ieo oa?aeoa?enoee a?o/eciyii? oano-nenoaie
«?OA-A?E 1/2» ? iiaeeeaino? ?? canoinoaaiiy aeey aeyaeaiiy aioeo?e aei
A?E.

2. Iaa?oiooaaiiy iieaciee?a, ye? oa?aeoa?ecothoue aoaeoeai?noue
ne?ei?iaiaeo aeine?aeaeaiue i?e aeei?enoaii? ??cieo ae?aaiinoeeoi?a aeey
aeyaeaiiy aioeo?e aei A?E iaoiaeii ?ioiioa?iaioiiai aiae?co.

3. No?aoaa?y niaoeeo?/ii? ?ioiiae?aaiinoeee A?E-?ioaeoe?? i?e
ianoaaeaii? ??cieo eiioeiaaio?a ianaeaiiy a caeaaeiino? a?ae
?ioaineaiino? ai?aeai?/iiai i?ioeano ? iaoe ianoaaeaiiy.

4. Iaa?oiooaaiiy no?oeoo?e ?ioi?iaoe?eii? i?aenenoaie a
ai?aeai?ieia?/iiio iaaeyae? ca A?E-?ioaeoe??th.

Ai?iaaoe?y ?iaioe

Iniiai? iieiaeaiiy aeena?oaoe?? aeiiia?aeaeeny ia O Ieaioi?
Oe?a?inueeiai iaoeiaiai oiaa?enoaa c ee?i?/ii? eaai?aoi?ii? ae?aaiinoeee
(1993), ia i?aenoieiaeo ia?aaeao-nai?ia?ao aieiaieo niaoe?ae?no?a c
ee?i?/ii? eaai?aoi?ii? ae?aaiinoeee oi?aae?iue ioi?iie caei?ia’y
iaeanieo ? i?nuee?i (Ee?anueei?, Naaanoiiieuenueei?) aea?aeaaieo
aaei?i?no?aoe?e, ?anioae?ee E?ei (1994, 1995), ia i?aeia?iaeiiio
neiiic?oi? «Eaeae Ianoa?a a ai?ueaa n eioaeoeeyie» (Naieo-Iaoa?ao?a,
1995), ia 3-e ? 4-e i?aeia?iaeieo eiioa?aioe?yo «NIEAe, ?ae e
?iaenoaaiiua i?iaeaiu» (Naieo-Iaoa?ao?a, 1995, 1996), ia O??? c’?cae?
Oe?a?inueeiai oiaa?enoaa i?e?ia?ieia?a, ai?aeai?ieia?a oa ia?aceoieia?a
?i. Ae.E.Caaieioiiai (1996), ia ?-e ? ??-e ?in?enueeeo
iaoeiai-i?aeoe/ieo eiioa?aioe?yo c i?aeia?iaeiith o/anoth «Aaiaoeo A, C,
D e G — i?iaeaiu eco/aiey, aeeaaiinoeee, ea/aiey e i?ioeeaeoeee»
(Iineaa, 1995, 1997).

Ai?iaaoe?y aeena?oaoe?? a?aeaoeany 16.07.98 ?. ia can?aeaii?
ai?iaaoe?eii? ?aaee ai?aeai?ieia?/iiai a?aeae?eo Ee?anueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ai?aeai?ieia?? oa ?ioaeoe?eieo oai?ia ?i.
E.A.A?iiaoaanueeiai IIC Oe?a?ie (EIAe?A?O).

Ca iaoa??aeaie aeena?oaoe?? iioae?eiaai? 12 ae?oeiaaieo ?ia?o, a oiio
/ene?, io?eiaiee 1 iaoaio ia aeiao?ae.

Ianya oa no?oeoo?a aeena?oaoe??

Aeena?oaoe?y aeeeaaeaia ia 169 noi??ieao iaoeiiieniiai oaenoo,
?ethno?iaaia 25 oaaeeoeyie oa 12 iaethieaie. Neeaaea?oueny c anooio,
iaeyaeo e?oa?aoo?e, iieno iaoa??ae?a oa iaoiae?a aeine?aeaeaiue, 4
?icae?e?a aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiae?a oa
a?ae?ia?ao??, yea i?noeoue 211 e?oa?aoo?ieo aeaea?ae.

A?eueoa 80 % ?iaioe aaoi?ii aeeiiai? naiino?eii.

I?eiineii ue?o iiaeyeo ni?a?ia?oieeai eaai?aoi??? ae?aaiinoe/ieo
aeine?aeaeaiue EIAe?A?O oa eaai?aoi??? NI?Aeo oa ?ioeo a??onieo
?ioaeoe?e Oe?a?inueeiai oeaio?o aea?aeaaiiai
nai?oa?ii-ai?aeai?ieia?/iiai iaaeyaeo ca aeiiiiiao i?e aeeiiaii? ?iaioe.

Iaoa??aee ? iaoiaee aeine?aeaeaiue

I?e aeeiiaii? ?iaioe aoee canoiniaai? ai?aeai?ieia?/i?, na?ieia?/i?,
?ioiieia?/i? ? noaoenoe/i? iaoiaee aeine?aeaeaiiy.

Ia’?eoe aeine?aeaeaiiy: ai?aeai?/iee i?ioean, nenoaia
ai?aeai?ieia?/iiai iaaeyaeo, iieacieee ?io?eiaaiino? A?E, i?aia?aoe
e?ia? ? ne?iaaoee e?ia? ??cieo eiioeiaaio?a ianoaaeoaaieo.

I?iaaaeaiee aiae?c ?acoeueoao?a eaai?aoi?iiai ianoaaeaiiy ia A?E 5496
c?ace?a e?ia?, 270 ?ioiiaeiaoe?iiaeo i?aia?ao?a. Aea/aee oaeoe/i? aeai?,
io?eiai? i?e i?iaaaeaii? ne?ei?iao ia A?E-?ioaeoe?th a ?yae? iaeanoae
oe?a?ie (10 iaeanoae), ca?oe eaai?aoi??? ae?aaiinoe/ieo aeine?aeaeaiue
EIAe?A?O.

C iaoith aecia/aiiy /ooeeaino? ? niaoeeo?/iino? oano-nenoaie «?OA-A?E
1/2» canoiniaoaaee noaiaea?oi? iaiae? iiceoeaieo ? iaaaoeaieo aei A?E
ne?iaaoie Aea?aeaaiiai ?inoeoooo noaiaea?oecaoe?? ? eiio?ieth ?i.
E.A.Oa?anaae/a (?in?y), iaiae? iiceoeaieo aei A?E ne?iaaoie,
ioa?aeoa?eciaai? a eaai?aoi??? ae?aaiinoe/ieo aeine?aeaeaiue EIAe?A?O, a
oaeiae ne?iaaoee, io?eiai? c Iaeanueeiai ia?eieia?/iiai oeaio?o.

Aeey ii??aiyeueieo aeine?aeaeaiue a ?iaio? aeei?enoiaoaaee ianooii?
oano-nenoaie aeey aeyaeaiiy aioeo?e aei A?E: «?aeiiaeiaio-AE*»,
«NE?EI-AE*», «Aioeaai», «Iaioine?ei-2» (?in?y), «ABBOT Recombinant
HIV1/HIV2 3rd» (NOA), «Genelavia mixt HIV-1+HIV-2» (O?aioe?y).
Aa?eo?eaoe?th ?acoeueoao?a na?ieia?/ieo aeine?aeaeaiue cae?enithaaee ca
aeiiiiiaith oano-iaai??a «New Lav Blot 1» (Diagnostics Pasteur) oa «HIV
2 Western Blot (Ig G)» (Diagnostics Biotechnology).

Ai?aeai?/iee i?ioean i?e A?E-?ioaeoe?? aea/aee ia iniia? iaoa??ae?a
Oe?a?inueeiai Oeaio?o i?io?eaeoeee ? ai?ioueae c? NI?Ae i?e EIAe?AO
(?ioi?iaoe?ei? atheaoai? «A?E-?ioaeoe?y a Oe?a?i? ?? 1-12).

Aecia/aiiy i?iaiicoth/i? caeaoiino? iiceoeaiiai ? iaaaoeaiiai oano?a
(ICIO ? ICIO) ?ioiiae?aaiinoe/ieo i?aia?ao?a cae?enithaaee ca
aeiiiiiaith oi?ioe, caniiaaieo ia iiaeeo?eiaaiiio ??oaii? oai?aie Aae?na
(Galen R.S., Gambino S.R., 1975; Iaiueoeeia A.A., 1978).

Noaoenoe/io ia?iaeo io?eiaieo aeaieo i?iaiaeeee c aeei?enoaiiyi
iaoiae?a aa??aoe?eii? noaoenoeee (Eaieineee E.N., 1964; ?oioeneee E.C.,
1971).

?ACOEUeOAOE OA ?O IAAIAI?AIIss

Aea/aiiy ae?aaiinoe/ieo oa?aeoa?enoee oano-nenoaie aeey aeyaeaiiy
aioeo?e aei A?E «?OA-A?E 1/2»

Ia Ee?anueeiio iaoeiai-ae?iaie/iio i?aei?e?inoa? «Ae?ai?io», ni?eueii
?c ni?a?ia?oieeaie EIAe?A?O, aoea noai?aia ia?oa a?o/eciyia
?ioiioa?iaioia oano-nenoaia aeey aeyaeaiiy aioeo?e aei A?E ia?oiai ?
ae?oaiai oei?a — «?OA-A?E 1/2» (iaoaio Oe?a?ie ia aeiao?ae ? 14501 A,
09.01.97 ?.). I?iaaaeai? aei?iaoaaiiy aenia?eiaioaeueieo,
aenia?eiaioaeueii-ae?iaie/eo oa ae?iaie/eo na??e ae?aaiinoeeoio «?OA-A?E
1/2» a iaiaaeaiiio oa oe?ieiio ai?aeai?ieia?/iiio aeine?ae?, c
aeei?enoaiiyi noaiaea?oieo iaiaeae aeey aecia/aiiy /ooeeaino? ?
niaoeeo?/iino?, a oaeiae i?aia?ao?a aeiii?nueei? e?ia? ? c?ace?a e?ia?
??cieo eiioeiaaio?a ianaeaiiy Oe?a?ie. ?acoeueoaoe aei?iaoaaiue
cao?eniaai? a Aiioiaaiiio ca?o? eaai?aoi??? ae?aaiinoe/ieo
aeine?aeaeaiue «Eniuoaiea aeeaaiinoe/aneeo iaai?ia «EOA-AE* 1/2»,
«Caeeth/aii? Eii?n?? i?i aei?iaoaaiiy oano-nenoaie «?OA-A?E 1/2»
ae?iaieoeoaa IAI «Ae?ai?io» a ae?aaiinoe/ieo eaai?aoi??yo ia NI?Ae
Oe?a?ie», a i?ioieieao aeine?aeaeaiue. Aeine?aeaeaiiy i?iaiaeeee
ia?aeaeueii c aeei?enoaiiyi ?ioeo ae?aaiinoe/ieo i?aia?ao?a
caei?aeiiiiai ae?iaieoeoaa (NOA, O?aioe?y, ?in?y). Ae?aaiinoe/i?
oa?aeoa?enoeee iaai?o «?OA-A?E 1/2» ia iaee noaoenoe/ii cia/oueo
a?aei?iiinoae a?ae aiaeia?/ieo iieaciee?a a oano-nenoaiao ii??aiyiiy.

Aeey ioe?iee niaoeeo?/iino? ae?aaiinoe/ieo aeine?aeaeaiue ca
aeiiiiiaith oano-nenoaie «?OA-A?E 1/2» a oiiaao ianiaiai ne?ei?iao
aea/aee ?acoeueoaoe eaai?aoi?ii? ae?aaiinoeee ia A?E-?ioaeoe?th a
Iaeanuee?e, Euea?anuee?e, Ieeiea?anuee?e, Noinuee?e,
Aei?i?iiao?ianuee?e, Caii??cuee?e, Iieoaanuee?e, Eoaainuee?e, Ee?anuee?e
oa E??iaia?aaenuee?e iaeanoyo.

A ii?iaoeaii-oaoi?/i?e aeieoiaioaoe?? ia oano-nenoaio «?OA-A?E 1/2»
?aaeaiaioiaai? iieacieee /ooeeaino? ? niaoeeo?/iino? ia ieae/a 98 %. I?e
aea/aii? ae?aaiinoe/ieo oa?aeoa?enoee iaai?o ca aeiiiiiaith
e?oeaiciaaieo eiio?ieueieo iaiaeae ? o oe?ieiio ai?aeai?ieia?/iiio
aeine?ae? aoei anoaiiaeaii, ui oe? iieacieee ae?enii neeaaeaee 98 % ?
a?eueoa. Oaeei /eiii, aoea iieacaia iiaeeea?noue aeei?enoaiiy
a?o/eciyieo oano-nenoai «?OA-A?E 1/2» aeey na?ieia?/iiai ne?ei?iao a
Oe?a?i?.

Aeei?enoaiiy iaoaiaoe/ieo i?aeoiae?a aeey aecia/aiiy niaoeeo?/iino? ?
aoaeoeaiino? ?ioiiae?aaiinoeee A?E-?ioaeoe??

Nooo?aith ia?aaeoiiaith aoaeoeaiiai ooieoe?iioaaiiy nenoaie AI ?
ia’?eoeaia ?ioi?iaoe?y i?i ??ai? ?iciianthaeaeaiiy ?ioaeoe?? na?aae
??cieo a?oi ianaeaiiy, i?i eiioeiaaioe i?aeaeuaiiai ?eceeo ?io?eoaaiiy
A?E oa ?io? ia?aiao?e, ui oa?aeoa?ecothoue ai?aeai?/iee i?ioean.
Iniaeeao cia/ou?noue iaaoaathoue na?iai?aeai?ieia?/i? aeine?aeaeaiiy ?c
canoinoaaiiyi no/anieo iaoiae?a ?ioiiae?aaiinoeee. I?ioa aei
oaia??oiueiai /ano ia ?ic?iaeai? iaoeiai iaa?oioiaai? i?aeoiaee aei
ioe?iee ?acoeueoao?a oaeeo aeine?aeaeaiue. Niaoeeo?/i? eaai?aoi?i?
aeine?aeaeaiiy a Oe?a?i? i?iaiaeyoueny o a?aeiia?aeiino? c ?aeeiith
i?eeiyoith no?aoaa??th ?ioiiae?aaiinoeee, aac o?aooaaiiy ??aiy
?iciianthaeaeaiiy ?ioaeoe??. I?aeoe/ii, aeai? oaeeo aeine?aeaeaiue
neoaeaoue aeey

a?aeiia?ae? ca i?eioeeiii «oae-i?» ? i?ney ?iciiae?eaiiy aeyaeaieo
?io?eiaaieo in?a o a?aeiia?aeiino? c oeie /e ?ioeie oeyoaie ia?aaea/? ?
a?oiaie ?eceeo ? aacith aeey iae?eo ? ?a?no?aoe?? aeiaaee?a
A?E-?ioaeoe?? ? NI?Aeo.

Oae? ia’?eoeai? oa?aeoa?enoeee ?OA-ae?aaiinoeeoi?a ye /ooeea?noue ?
niaoeeo?/i?noue aeey eiaeii? eiie?aoii? oano-nenoaie iino?ei? ? ia
caeaaeaoue a?ae ??aiy ?iciianthaeaeaiiy ?ioaeoe??, i?ioa, aacoiiaii, ?o
ne?ae ?icaeyaeaoe c oi/ee ci?o aieeao ia o?aeoiaeo e?ioeaaeo
?acoeueoao?a aeine?aeaeaiue. Aeey ioe?iee aoaeoeaiino? ne?ei?iaiaeo
oano?a iaiao?aeii a?aoiaoaaoe iieaciee, yeee aecia/a? ?acoeueoaoe
aeine?aeaeaiue a caeaaeiino? a?ae ??aiy ?iciianthaeaeaiiy ?ioaeoe??. Ie
aaaaea?ii oaeei iieacieeii i?iaiicoth/o caeaoi?noue oanoo (Sivac S.L.,
Wormser G.P., 1986). I?iaiicoth/a caeaoi?noue iiceoeaiiai oanoo (ICIO) —
eiia??i?noue oiai, ui iniae c iiceoeaiei ?acoeueoaoii ne?ei?iaiaiai
aeine?aeaeaiiy ae?enii iathoue aioeo?ea aei A?E a e?ia?. I?iaiicoth/a
caeaoi?noue iaaaoeaiiai oanoo (ICIO) — eiia??i?noue oiai, ui iniae c
iaaaoeaiei ?acoeueoaoii ?OA ae?enii ia iathoue a e?ia? aioeo?e. Ia iae.
1 i?aaenoaaeai? ICIO ? ICIO aeey oano-nenoaie «?OA-A?E 1/2», ?ic?aoiaai?
aeey a?iioaoe/ieo iiioeyoe?e, /enaeuei?noth 100000 /ieia?e ? c ??aiai
?iciianthaeaeaiiy A?E-?ioaeoe?? a?ae 0,1 % aei 99 %. Iieacaii, ui
ia?aeaeueii ?c c?inoaiiyi ?iciianthaeaeaiino? ?ioaeoe?? /anoea
oeaiiiiceoeaieo ?acoeueoao?a ne?ei?iaiaeo oano?a cieaeo?oueny, a
eiia??i?noue io?eiaiiy oeaiiiaaaoeaieo ?acoeueoao?a c?inoa?.

Iae. 1. Caeaaei?noue ICIO ? ICIO a?ae ??aiy ?iciianthaeaeaiino?
A?E-?ioaeoe??.

*ooeea?noue = 98 %. Niaoeeo?/i?noue = 98 %.

Ii in? aanoeen – ?iciianthaeaeai?noue;

ii in? i?aeeiao – cia/aiiy iieaciee?a.

Ei?aeoe?y ?acoeueoao?a eaai?aoi?iiai ianoaaeaiiy c o?aooaaiiyi aaee/ei
ICIO ? ICIO aeicaiey? c?iaeoe iiia?aaei?e aeniiaie i?i e?euee?noue
?io?eiaaieo in?a a eiie?aoi?e iiioeyoe?? aaea i?ney ia?oiai aoaio ?OA, a
oaeiae aecia/eoe aoaie aa?eo?eaoe?? ? iaiao?aei? aeo?aoi? iaoa??aee.

Iaeiei c aoai?a ?iaioe aoea ioe?iea aoaeoeaiino? ?nioth/eo no?aoaa?e
?ioiiae?aaiinoeee A?E-?ioaeoe?? ca aeiiiiiaith iaoiae?a ui a?aoiaothoue
aecia/aiiy i?iaiicoth/i? caeaoiino? oano?a ? ?o eiia?iaoe?e. A
oaia??oi?e /an canoiniaothoueny no?aoaa?? niaoeeo?/ii? eaai?aoi?ii?
ae?aaiinoeee A?E-?ioaeoe??, ?aeiiaiaeiaai? AIIC — ?, ?? ? ??? (C, D i
E), a oaeiae aea? no?aoaa?? (A ? A), yeeie ei?enoothoueny a Oe?a?i?
(oaae. 1).

Iaie aoee ?ic?aoiaai? eiia??i? ?acoeueoaoe aeine?aeaeaiue ia aioeo?ea
aei A?E a a?iioaoe/ieo a?oiao ianaeaiiy, /enaeuei?noth 100000 /ieia?e c
??aiai ?iciianthaeaeaiiy ?ioaeoe?? a?ae 0,1 % aei 30 % ?c canoinoaaiiyi
?nioth/eo no?aoaa?e eaai?aoi?ii? ae?aaiinoeee i?e aeei?enoaii?
oano-nenoai c «ona?aaeiaieie» iieacieeaie /ooeeaino? ? niaoeeo?/iino?.
Iaoith aoea ioe?iea aoaeoeaiino? eaai?aoi?ieo aeine?aeaeaiue c
aeei?enoaiiyi cacia/aieo no?aoaa?e. Aoaeoeai?noue aeine?aeaeaiue —
a?aeiioaiiy noie ae?enieo ?acoeueoao?a (iiceoeaieo ? iaaaoeaieo) aei
caaaeueiiai /enea ?acoeueoao?a ?ioiiae?aaiinoeee, ae?aaeaia o a?aenioeao
(Galen R.S., Gambino S.R., 1975).

Anoaiiaeaii, ui aoaeoeai?noue ??cieo ?ioiiae?aaiinoe/ieo i?aeoiae?a
caeaaeeoue a?ae ??aiy ?iciianthaeaeaiiy A?E-?ioaeoe??. I?e
?iciianthaeaeaiino? A?E-?ioaeoe?? aei 0,5 % aoaeoeai?noue on?o no?aoaa?e
iaeiaeiaa. sseui ??ai? ?iciianthaeaeaiiy ?ioaeoe?? neeaaeathoue 0,5-1,0
%, a?eueo aoaeoeaieie ? no?aoaa?? B i D; a?ae 5 aei 20 % — no?aoaa?y D,
20-30 % ? a?eueoa — no?aoaa?? D i E. Iacaeaaeii a?ae ??aiy
?iciianthaeaeaiiy A?E-?ioaeoe??, aoaeoeai?noue ne?ei?iaiaeo
aeine?aeaeaiue, ia?aaeaa/aieo no?aoaa??th N, iaeiaeiaa.

I?e an?o ??aiyo ?iciianthaeaeaiiy A?E-?ioaeoe?? aeei?enoaiiy
ae?aaiinoe/ieo i?aeoiae?a, ye? ?aaeaiaioiaai? a Oe?a?i?, i?aeoe/ii
oiaiiaeeeaeth? io?eiaiiy ia e?ioeaaiio aoai? ne?ei?iao oeaiiiiceoeaieo
?acoeueoao?a, a oie /an ye eiia??i?noue ?a?no?aoe?? oeaiiiaaaoeaieo
?aaeoe?e a na?aaeiueiio a 2-4 ?ace aeua, i?ae i?e no?aoaa?yo,
?aeiiaiaeiaaieo aenia?oaie AIIC. Canoinoaaiiy o??? /e ?ioi? no?aoaa??
na?ieia?/ii? ae?aaiinoeee A?E-?ioaeoe?? o a?aeiia?aeiino? c
?aeiiaiaeaoe?yie AIIC caeaaeeoue a?ae iaoe oanooaaiiy, a oaeiae a?ae
??aiy ?iciianthaeaeaiiy ?ioaeoe?? na?aae ianoaaeoaaieo eiioeiaaio?a. A
oie aea /an, no?aoaa?? aeyaeaiiy aioeo?e aei A?E, ui ?niothoue a
Oe?a?i?, ia?aaeaa/athoue iaeiaeiaee ae?aaiinoe/iee i?aeo?ae aei on?o
eaoaai??e ianoaaeoaaieo in?a (aeeeth/aiiy — aeiii?e e?ia?, i?aai?a,
oeaiei).

Oaeei /eiii, i?iaaaeai? ?ic?aooiee oa ?o aiae?c ? ii??aiyiiy c
oaeoe/iei iaoa??aeii iieacaee, ui iiia?aaei? aecia/aiiy i?iaiicoth/i?
caeaoiino? oano?a, ye? canoiniaothoueny aeey ?ioiiae?aaiinoeee
A?E-?ioaeoe??, aeicaieythoue ioe?-Oaaeeoey 1. No?aoaa?? eaai?aoi?ii?
ae?aaiinoeee A?E-?ioaeoe??

ACa?aeii c “?no?oe-

oe??th c i?aai?caoe??

?iaioe eaai?aoi-

??e ae?aaiinoeee

A?E-?ioaeoe??” Ia ia?oiio aoai? aeyaeythoueny iiceoeai? a ?OA

c?acee e?ia?, eio?? iio?i aeine?aeaeothoueny aae?oaa a o?ueio
eoieao o??? ae oano-nenoaie, a aeae? – i?e io?eiaii? iiceoeaiiai
?acoeueoaoo oi/a a a iaei?e eoioe? ieaioaoo – aa?eo?eaoe?eia
aeine?aeaeaiiy ca aeiiiiiaith iaoiaeo WBANo?aoaa?y, yeith

a oaia??oi?e /an

o a?eueoino? aeiaae-

e?a ei?enoothoueny

a Oe?a?i? Ne?iaaoee, iiceoeai? o a?aeiioaii? A?E i?ney ia?oiai
?OA-aeine?aeaeaiiy, i?aeeyaathoue aeine?aeaeai-

ith aae?oaa a aeaio eoieao oiai ae ae?aaiinoeeoio. On? io?eiai?
iiceoeai? c?acee iinooiathoue ia ?aoa?aioiee aoai – aeine?aeaeaiiy a
aeaio ?ioeo ?OA-oano nenoaiao c a?eueo aenieith niaoeeo?/i?nothNI
no?aoaa?y

?aeiiaiaeaoe?e

AIIC ? UNAIDS

(1997)

C?acee e?ia? aeine?aeaeothoueny ca iaoiaeii oaa?-

aeioaciiai ?OA aai i?inoiai/i?enei?aiiai oanoo. Ne?iaaoea, ui aeaea
iiceoeaiee ?acoeueoao, aaaaea- ?oueny ye i?noyua aioeo?ea aei A?E, ?
iaaiaeeDII no?aoaa?y

?aeiiaiaeaoe?e

AIIC ? UNAIDS

(1997) Ne?iaaoee, iiceoeai? i?ney ia?oiai ?OA-oanoo, i?aeeyaathoue
aeine?aeaeaiith aae?oaa ca aeiiiiiaith

?OA aai i?inoiai/i?enei?aiiai oanoo, yeee caniiaaiee ia
aeueoa?iaoeaiiio aioeaaiiiio i?aia?ao?. Ne?iaaoee, ye? a?ae?aaaoaaee
iiceoeaii a iaio aiae?cao, aaaaeathoueny ye i?noyu? aioeo?ea aei
A?E. sseui aeine?aeaeoaaiee c?acie iiceoeaiee a ia?oiio, aea
iaaaoeaiee a ae?oaiio aiae?c?, a?i i?aeeyaa? ia?aa??oe? ca
aeiiiiiaith iaio aeei?enoa- ieo ae?aaiinoeeoi?a. sseui ?acoeueoaoe
caeeoathoue-ny noia?a/ieie, ne?iaaoea aaaaea?oueny iaaecia/a-

iith ii a?aeiioaiith aei aioe-A?EEIII no?aoaa?y

?aeiiaiaeaoe?e

AIIC ? UNAIDS

(1997)

Ia?aaeaa/a? oaeee naiee i?aeo?ae, ye ? iiia?aaeiy.

Iaeiae, a caeaaeiino? a?ae iaoe oanooaaiiy, a oaeiae ??aiy
?iciianthaeaeaiiy ?ioaeoe?? na?aae ianoaaeo-

aaieo eiioeiaaio?a /e ia eiie?aoi?e oa?eoi???, iaaecia/ai?
?acoeueoaoe i?aeeyaathoue ua iaeiiio aia- e?co ?c canoinoaaiiyi
aeiaeaoeiaiai oanoo (IOe?, WB)

ieoe ?acoeueoaoe oanooaaiiy ia aioeo?ea aei A?E c aeei?enoaiiyi ??cieo
oano-nenoai a caeaaeiino? a?ae eiie?aoii? ai?aeai?/ii? neooaoe??.
Aaaaea?ii, ui oe? iieacieee iiaeii? a?aoiaoaaoeny i?e ?ic?iaoe?
no?aoaa?e eaai?aoi?ieo aeine?aeaeaiue ia A?E-?ioaeoe?th a Oe?a?i?. Aeey
ae??oaiiy ieoaiiy i?i aeeeth/aiiy oeaieo ?acoeueoao?a iaiao?aeii ie??i
?OA canoiniaoaaoe ?io? iaoiaee aeine?aeaeaiue (WB, IOe?, oiui). Aaaeaii
oaeiae aeei?enoiaoaaoe aeae?eueea aeueoa?iaoeaieo nenoai.

Ii??aiyeueia ioe?iea ??cieo no?aoaa?e niaoeeo?/ii? ?ioiiae?aaiinoeee
A?E-?ioaeoe?? oa ?o ?ieue a ?ioi?iaoe?eiiio caaacia/aii?
ai?aeai?ieia?/iiai iaaeyaeo

O a?aeiia?aeiino? aei aeei?enoaiiai aeai?eoio aoee ia/eneai? eiia??i?
oeaiiniaoeeo?/i? ?acoeueoaoe na?ieia?/iiai ne?ei?iao ia iniia?
?acoeueoao?a ianoaaeaiiy ia A?E-?ioaeoe?th ??cieo eiioeiaaio?a ianaeaiiy
Oe?a?ie o 1997 ?ioe? ?c canoinoaaiiyi ?nioth/eo no?aoaa?e
?ioiiae?aaiinoeee (oaae. 2; eiae 101 –iniae, ye? iaee noaoaa? eiioaeoe c
A?E-?io?eiaaieie; 102 – ia?eiiaie; 104 – oai?? ia aaicaoai?thaaiiy; 105
– iniae, ye? iathoue aaaaoi noaoaaeo ia?oia??a; 108 – aeiii?e e?ia?,
?ioeo a?ieia?/ieo ??aeei, oeaiei; 109 – aaa?oi?; 112 – iniae, ye?
ciaoiaeyoueny a i?noeyo a?aeaoaaiiy iiea?aiiy; 113 – ianoaaeai? ca
ee?i?/ieie iieacaiiyie; 114 – ianoaaeai? aeia?ia?eueii – eii-

o?aeaoe?eii aai aiii?iii; 115 – iaaee/i? eiioaeoe; 120 – ?io?). sseui
aeoiaeeoe c oiai, ui o 1997 ?ioe? a na?aaeiueiio aeey an?o eaoaai??e
ianoaaeoaaieo ??aaiue ?io?eiaaiino? neeaaeaa 0,6 % (2538948
aeine?aeaeaiue), oi ae?aaiinoe/i? i?aeoiaee no?aoaa?e, ui
aeei?enoiaothoueny a Oe?a?i?, ni?yiiaai? ia iaeneiaeueia aeeeth/aiiy
oeaiiiiceoeaieo ?acoeueoao?a aeine?aeaeaiue, iiai?noth a?aeiia?aeathoue
oeei oe?eyi. Iaeiae ni?aa?aeiioaiiy e?eueeino? ianoaaeoaaieo in?a ?
aeyaeaieo na?aae ??cieo a?oi ianaeaiiy A?E-iiceoeaieo ? iai?iii?oe?eiei.
Iai?eeeaae, o 1997 ?. 4,69 % a?ae on?o aeyaeaieo A?E-?io?eiaaieo
neeaee aeiii?e, aea ia ?o aeieth i?eoiaeeeiny 46,45 % on?o eaai?aoi?ieo
ianoaaeaiue (??aaiue ?io?eiaaiino? 0,06 %). C ?ioiai aieo, 51 %
aeiaaee?a A?E-?ioaeoe?? aoa aeyaeaiee i?e ianoaaeaii? ia?eiiai?a, a
ieoiia aaaa in?a, ui iaeaaeaoue aei oeueiai eiaeo iae?eo, neeaaeaea eeoa
2,85 % (??aaiue ?io?eiaaiino? 10,8 % — o 180 ?ac?a a?eueoee, i?ae na?aae
aeiii??a). Ia aeeaey/enue ia oaea ia??aiii??ia ?iciiae?eaiiy aeyaeaieo
aeiaaee?a A?E-?io?eoaaiiy na?aae ??cieo eaoaai??e a?iiaaeyi (iae. 2), a
Oe?a?i? aeei?enoiaothoue ?aeeiee i?aeo?ae ?ioiiae?aaiinoeee, ui iiaea
i?eaanoe aei aee?eaeaiiy ae?enii? ea?oeie ai?aeai?/ii? neooaoe??.

Canoinoaaiiy o??? /e ?ioi? no?aoaa?? oanooaaiiy ia A?E aaaea aei
ci?iaiiy niaoeeo?/iino? aeine?aeaeaiue o a?e oeaiiiiceoeaieo aai
oeaiiiaaaoeaieo ?acoeueoao?a. Ia aeeeeea? noii?ao aeniea cia/aiiy
i?iaeaie oeaiiiiceoeaieo ?acoeueoao?a. C ?ioiai aieo, oeaiiiaaaoeai?
?acoeueoaoe iathoue i?eioeeiiaa

Oaaeeoey 2. E?euee?noue oeaiiniaoeeo?/ieo ?acoeueoao?a ianoaaeaiiy

ia A?E-?ioaeoe?th i?e canoinoaaii? ??cieo no?aoaa?e ?ioiiae?aaiinoeee

No?aoaa?yOeaiiiiceoeai? ?acoeueoaoeOeaiiiaaaoeai? ?acoeueoaoeIaaecia/ai?

?acoeueoaoeEiae 101; ?iciianthaeaeai?noue – 8,35 %; 5807
ianoaaeaieoA0190A0102D0,5850A0,5850,2Eiae 102; ?iciianthaeaeai?noue –
10,8 %; 72480 ianoaaeaieoA03090A015438D6780A6773Eiae 104;
?iciianthaeaeai?noue – 0,55 %; 192034
ianoaaeaieoA0440A0236D19110A191110Eiae 105; ?iciianthaeaeai?noue – 0,55
%; 49095 ianoaaeaieoA0110A061D530A532Eiae 109; ?iciianthaeaeai?noue –
0,09 %; 325550 ianoaaeaieoA0130A070D3330A33316Eiae 112;
?iciianthaeaeai?noue – 2,44 %; 101699
ianoaaeaieoA0980A04912D10240A10245Eiae 113; ?iciianthaeaeai?noue —
0,58 %; 194323 ianoaaeaieoA0450A0236D19120A191210Eiae 114;
?iciianthaeaeai?noue – 1,41 %; 28969 ianoaaeaieoA0160A082D340A341

ai?aeai?ieia?/ia cia/aiiy, oiio ui iiaeooue iieeeeaoe ca niaith
ia?aaea/o a??ono, ui iniaeeai aeooaeueii, yeui ia?ici?ciaiei aeaea?aeii
?ioaeoe?? ? ethaeeia, yea iaeaaeeoue aei a?oie i?aeaeuaiiai ?eceeo
?io?eoaaiiy. I?aeoiaee aei niaoeeo?/ii? eaai?aoi?ii? ae?aaiinoeee
A?E-?ioaeoe?? iiaeii? aooe aeeoa?aioe?eiaaieie ? aacoaaoeny ia iaaiiio
«a?aee?eiaiio» ??ai? ?iciianthaeaeaiiy ?ioaeoe?? a o?e /e ?io?e a?oi?
ianaeaiiy, c o?aooaaiiyi nioe?aeueii-iiaaae?ieiaiai noaoono
ianoaaeoaaii? iniae ? iaoe ianoaaeaiiy. Oaeee i?aeo?ae aoaea ni?eyoe
iaeneiaeueii iiaiiio aeyaeaiith aeaea?ae ?ioaeoe?? ? io?eiaiith
iaea?eueo ia’?eoeaii? ?ioi?iaoe?? i?i ??ai? ?io?eiaaiino?,
?iciiae?eaiiy aeiaaee?a A?E-?ioaeoe?? a ??cieo aaia?ao?/ieo ?aa?iiao oa
na?aae ??cieo eiioeiaaio?a ianoaaeaieo oiui.

Ia aac? i?iaaaeaieo ?ic?aooie?a, a oaeiae aiae?co aeaieo e?oa?aoo?e
i?iiiio?oueny no?aoaa?y niaoeeo?/ii? eaai?aoi?ii? ae?aaiinoeee
A?E-?ioaeoe?? a Oe?a?i?, i?ae yeith ?icoi??oueny aeeoa?aioe?eiaaiee
i?aeo?ae aei ianoaaeaiue ??cieo eaoaai??e a?iiaaeyi, a?aoiaoth/e
?iciianthaeaeai?noue ?ioaeoe?? oa iaoo ianoaaeaiiy (oaae. 3).

Oaeineiiaeaiiy nenoaie ai?aeai?ieia?/iiai iaaeyaeo ca A?E-?ioaeoe??th

Ca no/anieie oyaaie, ai?aeai?ieia?/iee iaaeyae ? iaea?eueo aeiaa?oaiith
oi?iith oi?aae?iiy ai?aeai?/iei i?ioeanii (Iie?ianeee A.E., 1986;
Oaoaieia E.E. oa ?i., 1987). Oe?e?nia nenoaia AI neeaaea?oueny c
?ioi?iaoe?eii?, ae?aaiinoe/ii? oa eiio?ieueii? i?aenenoai (Aaeyeia
A.Ae., 1985). Iniiaiei aeaiaioii AI a oe?eiio ? ?ioi?iaoe?eia
i?aenenoaia. Oaea noaiiaeua aeooaeueia ianaiia?aae aeey ?ioaeoe?e, i?e
eio?eo ?ioaineai?noue i?eoiaaii i?io?eath/iai ai?aeai?/iiai i?ioeano
ia?aaeuo? iai?oanoi? i?iyae, ui aecia/a? neeaaeiino? o ieaioaaii?,
i?aai?caoe?? ? i?iaaaeaii? i?ioeai?aeai?/ieo ? i?io?eaeoe/ieo caoiae?a.
Oey i?aenenoaia caaacia/o? iiaeeea?noue io?eiaiiy ?ioi?iaoe?? i?i
aieiai? ia?aiao?e, ui oa?aeoa?ecothoue ai?aeai?/iee i?ioean a on?o eiai
i?iyaeaiiyo. ?acii c oei, ?ioi?iaoe?eia i?aenenoaia AI ca
A?E-?ioaeoe??th. oa ?? no?oeoo?a aei oaia??oiueiai /ano ?ic?iaeai?
iaaeinoaoiuei.

No?oeoo?a ?ioi?iaoe?eii? i?aenenoaie AI aeeth/a? ia’?eoe, ?a?no?o?i?
iciaee, ia?ea?e (ee?i?/i?, ?ioiieia?/i?, na?ieia?/i?), iaoiaee
?a?no?aoe??, ianoaaeoaai? eiioeiaaioe, onoaiiae-aeeiiaaoe? ?a?no?aoe??.
Aea a aeai?e ?iaio? iiaa eaea, ia?o ca ana, i?i ?a?no?o?i? iciaee i?e
A?E-?ioaeoe??, iaoiaee ?a?no?aoe?? oa eiioeiaaioe ianoaaeoaaieo in?a.

Oae? iaea?eueo a?aeii? ?a?no?o?i? iciaee ye caoai?thaai?noue,
nia?oi?noue, eaoaeuei?noue, oiui, caaaeyee oi?eaeueiei ai?aeai?ieia?/iei
iniaeeainoyi A?E-?ioaeoe??/NI?Aeo, aecia/eoe i?aeoe/ii iaiiaeeeai,
ine?eueee aiie ia a?aeia?aaeathoue ae?enio ai?aeai?/io neooaoe?th, ia
a?aoiaothoue ??ci? aniaeoe ai?aeai?/iiai i?ioeano. Aeani?
niinoa?aaeaiiy, a oaeiae aiae?c aeaieo e?oa?aoo?e (Chin J., 1990;
Iie?ianeee A.A., 1996) aeicaieeee iai i?eeoe aei aeniiaeo, ui ia
no/aniiio aoai? ?icaeoeo o/aiiy i?i ai?aeai?/iee i?ioean i?e
A?E-?ioaeoe?? iaiao?aeii ei?enooaaoeny ?ioeie ia’?eoeaieie iieacieeaie.
A ia?oo /a?ao, oea iieaciee ?iciianthaeaeaiino?: ca iaaiee ia??iae;
iieaciee /anoioe (?ioaineaiino?) ?iciianthaeaeaiiy ?ioaeoe?? — /enei
iiaeo aeiaaee?a ?io?eoaaiiy na?aae ie?aieo a?oi ianaeaiiy ? a iaaieo
?aa?iiao; iieaciee iiiaioii? ?iciianthaeaeaiino? — /enei A?E-?io?eiaaieo
ca ye iiaeia ei?iooee i?ii?aeie /ano (1-2 i?nyoe?).

Aeey ?ioi?iaoe?eiiai caaacia/aiiy AI ca A?E-?ioaeoe??th iaiao?aeiee
aeeoa?aioe?eiaaiee i?aeo?ae aei eaai?aoi?ieo aeine?aeaeaiue, a
caeaaeiino? a?ae iaoe ianoaaeaiiy ia A?E, ? ??aiy ?iciianthaeaeaiiy
?ioaeoe??. ?acoeueoaoe na?ieia?/iiai ne?ei?iaa — ia o?eueee iniiaa
ia’?eoeaii? ?a?no?aoe?? aeiaaee?a A?E-?ioaeoe?? ? NI?Aeo c oi/ee ci?o
e?euee?nii? ioe?iee, aea e aeyaeaiiy oaeoi??a, ye? iiaeooue iaaaoeaii
aieeaaoe ia ai?aeai?/io ianoaiiaeo.

Eiioeiaaioe aeey na?ieia?/iiai ianoaaeaiiy aecia/athoueny a caeaaeiino?
a?ae oiai, c yeith iaoith cae?enith?oueny ianoaaeaiiy, a?ae iiaeeeaino?
?aae?caoe?? oiai /e ?ioiai iaoai?cio ia?aaea/?, a oaeiae o
a?aeiia?aeiino? aei i?eeiyoi? eeaneo?eaoe?? a?oi ianaeaiiy ca ??aiyie
?eceeo ?io?eoaaiiy.

O a?aeiia?aeiino? aei ?aeiiaiaeaoe?e AIIC, ne?ei?iaia? ianoaaeaiiy
i?iaiaeyoueny aieiaiei /eiii c iaoith aaciaee
o?ainooc?eieo/o?ainieaioaoe?e-ieo caoiae?a, ae?aaiinoeee,
ai?aeai?ieia?/iiai iaaeyaeo oa iaoeiaeo aeine?aeaeaiue. C iaoi? oi/ee
ci?o, on? ia?ae?/ai? oe?e? oanooaaiiy ia A?E ia?ic?eaii iia’ycai? c
iaoith ?ioi?iaoe?eiiai caaacia/aiiy AI ca A?E-?ioaeoe??th a oe?eiio,
oiio ui iaiiaeia ?icaeyaeaoe AI eeoa c iiceoe?? ocaaaeueiaiiy
?acoeueoao?a eaai?aoi?ieo aeine?aeaeaiue. ?iciiae?e eaai?aoi?ieo
aeine?aeaeaiue ia ae?aaiinoe/i?, i?io?eaeoe/i? oa ca ai?aeai?/ieie
iieacaiiyie ia iiaeiai iaoe ca iaoo a?aeie?aieoe eiaeiee iai?yi, a
neoaeeoue iaoai?ciii aeey aaeaeaaoiiai aeai?o eaai?aoi?ieo iaoiae?a ?
ii?yaeeo ?o aeei?enoaiiy a eiie?aoieo oiiaao. Aei oeueiai ia?ae?eo
aeine?aeaeaiue o?aaa aeiaeaoe oaeiae ieaiii??i? oe?eueia? ianoaaeaiiy
iaaieo a?oi ianaeaiiy. Oae? ianoaaeaiiy ? neeaaeiaith /anoeiith, oae
caaiiai, aeici?iiai (noi?iaeiaiai) AI, a iniia? yeiai eaaeeoue
nenoaiaoe/ia cae?aiiy ? aiae?c aeaieo i?i oaiaeaioe?? A?E-?ioaeoe?? o
aea??eiaeo a?oiao ianaeaiiy, c?noaaeaieo a ??cieo ?aa?iiao.
Aeno?aiieyoe?y ?acoeueoao?a aeici?iiai AI aeicaieeoue anoaiiaeoe ae?enio
?iciianthaeaeai?noue A?E-?ioaeoe?? a oe?eiio aai na?aae o??? /e ?ioi?
a?oie ianaeaiiy. Oea, a naith /a?ao, aeicaieeoue caaacia/eoe aaeaeaaoio
nenoaio caoiae?a i?io?eaeoeee ? ai?ioueae, ?ic?iaeoe i?e iaiao?aeiino?
aea??eiai ni?yiiaai? i?ioeai?aeai?/i? caoiaee, ioe?ieoe ?o
aoaeoeai?noue, ?aoe?iiaeueii ?iciiae?eeoe o?iainia? aeo?aoe. Cai?noue
ianeaiiai iaeiie/aiiy aeaieo ? ii??aiyiiy ?o c ii-ia?aaei?ie ia??iaeaie
iaiao?aeiee aeoeaiee aiae?c iino?eii? iia?aoeaii? ?ioi?iaoe?? a ??cieo
aeaiia?ao?/ieo ? iiaaae?ieiaeo a?oiao ianaeaiiy, a oaeiae o /an?.

Oaaeeoey 3. No?aoaa?y eaai?aoi?iiai ianoaaeaiiy ia A?E-?ioaeoe?th a
Oe?a?i?

Iaoa ia-

noaaeaiiyIanoaaeoaai?

eiioeiaaioeAe?aaiinoe/iee

i?aeo?aeI?io?eae-

oe/i? ianoa-aeaiiyAeiii?e e?ia?, ?ioeo a?ieia?/ieo ??aeei, i?aai?a,
oeaiei Ne?iaaoee aeine?aeaeothoueny a ?OA-oano-nenoai?.
Iiceoeai? c?acee aaaaea-thoueny i?noyueie aioeo?ea aei A?E Aaa?oi?,
iniae, ye? ia iaeaaeaoue aei a?oi ?eceeo ?io?eoaaiiy A?E (??aaiue
?iciianthaeaeaiiy ?ioaeoe?? aei 0,5 %)Ne?iaaoee aeine?aeaeothoueny a
?OA — oano-nenoai?; iiceoeai? c?acee aae?oaa oanoothoueny a aeaio
eoieao oiai ae ae?aa-

iinoeeoio. Ciia io?eiai? iiceoeai? c?acee i?aeeyaathoue
aa?eo?eaoe?eiiio aiae?co ia?aeaeueii a aeaio aeueoa?ia- oeaieo
oano-nenoaiao. I?e iaaecia/a-ieo ?acoeueoaoao – aeei?enoaiiy aeiaeao-

eiaiai iaoiaeo (IOe?, WB)Ca ai?aeai?/-ieie

iieacai-

iyie Aaa?oi?, iniae, ye? ia iaeaaeaoue aei a?oi ?eceeo ?io?eoaaiiy
A?E (??aaiue ?iciianthaeaeaiiy ?ioaeoe?? aei 0,5 %) Iiceoeai?
i?ney 1-ai ?OA c?acee aeine?aeaeothoueny a aeueoa?iaoeai?e
oano-nenoai?. Iiceoeai? i?ney i?iaaaeaiiy aeaio aiae?c?a c?acee
aaaaeathoueny i?noy-

ueie aioeo?ea aei A?E. sseui ne?iaaoea iiceoeaia a ia?oiio, aea
iaaaoeaia a ae?oaiio oanooaaii?, ?? iaiao?aeii aei-

ne?aeaeoaaoe ca aeiiiiiaith iaio canoi-

niaaieo ae?aaiinoeeoi?a. I?e noia?a/-

ieo ?acoeueoaoao aiae?co iiaeaeueoo aa-?eo?eaoeeth i?iaiaeyoue c
o?aooaaiiyi ai?aeai?/ii? neooaoe?? ? iiaaae?ieiai?
oa?aeoa?enoeee ianoaaeoaaii? iniaeIniae, ye? ciaoiaeyoueny a i?noeyo
iicaaaeaiiy aie?I?io?eae-oe/i? ia-noaaeaiiy Iniae, ye? iaeaaeaoue
aei a?oi ?eceeo ?io?eoaaiiy

(??aaiue ?iciianthaeaeaiiy ?ioaeoe?? 0,5-10 %)Ca ai?aea-i?/ieie

iieacai-

iyieCa ee?-

i?/ieie

iiea-

caiiyieOe?eueia? ianoa-aeaiiy a aeici?ieo

a?oiao??ci? eiioeiaaioeCa ai?aea-

i?/ieie

iieacai-iyie ??ci? eiioeiaaioe (??aaiue

?iciianthaeaeaiiy ?ioaeoe?? a?eueoa 10 %) Iaaecia/ai? ?acoeueoaoe
aeine?aeaeaiiy, ye? aoee io?eiai? i?ney i?iaaaeaiiy cacia/aieo aeua
aiae?c?a, i?aeeyaathoue aa?eo?eaoe?? ca aeiiiiiaith aeiaeaoeiaiai
iaoiaeo – IOe?, WBIniae, ye? ianoaaeothoueny aiii?iiiCa ee?-

i?/ieie

iiea-

caiiyieIniae, ye? ia a?aeiinyoueny aei a?oi ?eceeo ?io?eoaai-

iy A?E

*?oea ooieoe?iioaaiiy on?o neeaaeiaeo aeaiaio?a ?ioi?iaoe?eii?
i?aenenoaie AI ca A?E-?ioaeoe??th, oi?ioaaiiy ii?yaeeo ?ioi?iaoe?eii?
aca?iiae?? i?ae i?ae?icae?eaie AI, i?ae ai?aeai?ieia?/iei ? eaai?aoi?iei
iai?yieaie c o?aoo aaiiyi cai?iiiiiaaiiai iaie na?iai?aeai?ieia?/iiai
caaacia/aiiy aeicaieeoue ia o?eueee aecia/eoe iniiai? ia?aiao?e
?ioaeoe?eiiai i?ioeano, aea e ioe?ieoe aeioe?euei?noue i?ioeai?aeai?/ieo
? i?io?eaeoe/ieo caoiae?a c iaoith ?o ia?aaeyaeo ? eiie?aoecaoe??.
E?ioeaaith iaoith AI a oe?eiio ? ?ic?iaea ? ?aae?caoe?y iaoeiai
iaa?oioiaaii? nenoaie caoiae?a ai?ioueae ? i?io?eaeoeee, ? aoaeoeai?noue
AI caeaaeeoue a?ae oiai, iane?eueee nai?/anii ? oe?eani?yiiaaii
aeei?enoiaothoue eiai ?acoeueoaoe i?e ieaioaaii? ? ?aae?caoe??
i?io?eaeoe/ieo caoiae?a (*a?eanneee A.E., 1988, 1990).

AENIIAEE

1. Aia?oa a Oe?a?i? i?iaaaeaia ii??aiyeueia ioe?iea aoaeoeaiino?
canoinoaaiiy ??cieo no?aoaa?e ?ioiiae?aaiinoeee A?E-?ioaeoe?? ?
?ic?iaeai? iaoeia? i?aeoiaee aei canoinoaaiiy no?aoaa?e niaoeeo?/ii?
eaai?aoi?ii? ae?aaiinoeee a Oe?a?i? aeey ianoaaeaiiy ??cieo a?oi
ianaeaiiy a caeaaeiino? a?ae ?ioaineaiino? ai?aeai?/iiai i?ioeano ? iaoe
ianoaaeaiiy ia A?E.

2. Aecia/ai? ae?aaiinoe/i? oa?aeoa?enoeee ia?oi? a?o/eciyii?
oano-nenoaie aeey aeyaeaiiy aioeo?e aei A?E ia?oiai ? ae?oaiai oei?a
«?OA-A?E 1/2» ? iieacaia iiaeeea?noue ?o canoinoaaiiy aeey eaai?aoi?iiai
caaacia/aiiy AI ca A?E-?ioaeoe??th a Oe?a?i?.

3. Cai?iiiiiaai? iaoaiaoe/i? iiaeae? aeey ioe?iee aoaeoeaiino?
niaoeeo?/ieo eaai?aoi?ieo aeine?aeaeaiue ia A?E-?ioaeoe?th/NI?Ae.

4. Aeiaaaeaii, ui i?iaiicoth/a caeaoi?noue oano?a aecia/a?
aoaeoeai?noue ne?ei?iaiaeo aeine?aeaeaiue a caeaaeiino? a?ae ??aiy
?iciianthaeaeaiiy A?E-?ioaeoe??, ? iiaea aooe iieeaaeaiith a iniiao
?ic?iaee no?aoaa?? eaai?aoi?ieo aeine?aeaeaiue ia A?E-?ioaeoe??.

5. Aeiaaaeaii, ui aeey aaeaeaaoii? ai?aeai?ieia?/ii? ioe?iee
?acoeueoao?a na?ieia?/iiai ne?ei?iao aieiaio ?ieue a?ae?a?a? aea??
no?aoaa?? niaoeeo?/ii? eaai?aoi?ii? ae?aaiinoeee o a?aeiia?aeiino? aei
??aiy ?iciianthaeaeaiino? A?E-?ioaeoe?? a eiie?aoiiio ?aa?ii? aai na?aae
iaaieo eiioeiaaio?a oa o?aceeaeo a?oi ianaeaiiy a caeaaeiino? a?ae iaoe
ianoaaeaiiy.

6. Aaeineiiaeaia ?ioi?iaoe?eia i?aenenoaia ai?aeai?ieia?/iiai iaaeyaeo
ca A?E-?ioaeoe??th.

IA?AE?E ?IA?O, UI IIOAE?EIAAI? CA OAIITH AeENA?OAOe??

1. Na?aaaaa O.A., Naiaiiaa I.I. Eco/aiea aeeaaiinoe/aneie oeaiiinoe
oano-nenoaiu «?OA-A?E 1/2» aeey auyaeaiey aioeoae e ae?ono
eiioiiaeaoeoeeoa /aeiaaea //Eaai?aoi?iay aeeaaiinoeea. — 1997. — ? 2. —
N. 34-39.

2. Iaea?aeaiiy ?aeiia?iaioieo a?ee?a A?E oa ?o ?ioiio?i?/ia
oa?aeoa?enoeea /Ia?oeiaiei Ae.E., Na?aa?aa O.A., *oiae ?.I. oa ?i.//
I?e?ia?ieia?/iee aeo?iae. — 1996. — O. 58, ? 6. — N. 67-70.

3. Iao. Oe?a?ie IEE O 61 E 39/21, N 12 Q 1/ «Niin?a aeey aeyaeaiiy
aioeo?e o ethaeeie i?ioe a??on?a ?ioiiaeao?oeeoo ethaeeie ia?oiai ?
ae?oaiai oeio (oano-nenoaia «?OA-A?E 1/2») /*oiae ?.I., Ia?oeiaiei
Ae.E.,Ua?a?inueea A.I., Ao?aeue A.E., Aeaen??iei ?.E., Ii??ieia I.N.,
Ia?e/aa Ae.E., Na?aa?aa O.A. oa ?i. – UA ? 14501 A; Cayae. 26.04.95;
Iioae. 9.12.96.- 1 n.

4. Na?aaaaa O.A., Ia?ouiaiei Ae.E., *aioeiaa I.I. ?acoeueoaou ai?iaaoeee
oano-nenoaiu «?OA-A?E 1/2» i?iecaiaenoaa III «Aeeai?io, Eoae //3-y
iaaeaeoia?iaeiay eiioa?aioeey «NIEAe, ?ae e ?iaenoaaiiua i?iaeaiu». —
NIA. — 1995. — N. 52.

5. ?ac?aaioea oano-nenoaiu EOA aeey ne?eieiaa aioeoae e ae?ono
eiioiiaeaoeoeeoa /aeiaaea 1 e 2 oeiia / Ia?ouiaiei Ae.E., Na?aaaaa O.A.,
Eaaineay I.A. e ae?. //Oai aea. — N. 53.

6. Oanoe?iaaiea nuai?ioie io AE*-eioeoee?iaaiiuo iaoeeaioia ec
?acee/iuo ?aaeiiia / Ia?ouiaiei Ae.E., Na?aaaaa O.A., Eaaineay I.A. e
ae?. //4-y Iaaeaeoia?iaeiay eiioa?aioeey «NIEAe, ?ae e ?iaenoaaiiua
i?iaeaiu». — NIA. — 1996. — N. 158.

7. I?iaeieaeeoaeueiinoue aeecie aieueiuo NIEAeii a Oe?aeia / Ia?e/aa E.,
Oaaei?oe I., E?oaeia TH., Ai?aaeyae I., I?ioeai A., Na?aaaaa O. //oai
aea. — N. 149.

8. Na?aaaaa O.A., Ia?ouiaiei Ae.E. Aeeaaiinoe/aneee iaai? «?OA-A?E 1/2»
— ia?aay oe?aeineay oano-nenoaia aeey auyaeaiey aioeoae e AE* n iieiui
oeeeeii i?iecaiaenoaa //Iaaeaeoia?iaeiue neiiiceoi «Eaeae Ianoa?a a
ai?ueaa n eioaeoeeyie. — NIA. — 1995. — N. 117.

9. Eiioiieiae/aneee iiieoi?eia AE*-eioeoee?iaaiiuo a?aaeaeai Oe?aeiu /
Ia?e/aa E.E., I?ioeai A.E., Ua?aeineay A.I., Na?aaaaa O.A. //Oai aea. —
N. 112.

10. ?iciianthaeaeaiiy aaiaoeoo «A» ye ?iaeeeaoi? aeoeaiino? ia?aaea/?
A?E-?ioaeoe?? / Oaa?iyi A.?., E?oaeia TH.A., Na?aa?aa O.A., Ii?icia A.O.
//O??? c’?cae Oe?a?inueeiai oiaa?enoaa i?e?ia?ieia?a, ai?aeai?ieia?a oa
ia?aceoieia?a ?i. Ae.E.Caaieioiiai. — A?iieoey. — 1996. — N. 174.

11. Yieaeaieieiae/aneea ia?aeeaee iaaeaeo aaiaoeoii A e AE* ia Oe?aeia
/E?oaeia TH.A., Oaaeiyi A.?., Na?aaaaa O.A., Iaiueei A.A. //II-y
?inneeneay iao/ii-i?aeoe/aneay eiioa?aioeey n iaaeaeoia?iaeiui o/anoeai
«Aaiaoeo A, N, D, e G — i?iaeaiu eco/aiey, aeeaaiinoeee, ea/aiey e
i?ioeeaeoeee». — Iineaa. — 1997. — N. 114.

12. Iineoaeuenoai ia?ea?ia aaiaoeoa A e N o AE*-eioeoee?iaaiiuo e
aieueiuo NIEAe a Oe?aeia / I?ioeai A.E., Ao?aeue A.E., Ia?e/aa E.E.,
Oaaeiyi A.?., Na?aaaaa O.A. //Iao/ii-i?aeoe/aneay eiioa?aioeey «Aaiaoeo
A, N,

e D — i?iaeaiu eco/aiey, aeeaaiinoeee, ea/aiey e i?ioeeaeoeee». —
Iineaa. — 1995. — N. 114.

AIIOAOe?ss

Na?aa?aa O.A. Niaoeeo?/ia ?ioiiae?aaiinoeea a nenoai?
ai?aeai?ieia?/iiai iaaeyaeo ca A?E-?ioaeoe??th. — ?oeiien.

Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe
ca niaoe?aeuei?noth 14.02.02 — ai?aeai?ieia?y. — Iaoeiai-aeine?aeiee
?inoeooo ai?aeai?ieia?? oa ?ioaeoe?eieo oai?ia ?i. E.A.A?iiaoaanueeiai,
Ee?a, 1998.

Aeena?oaoe?th i?enay/aii aea/aiith ?ie? no/anieo iaoiae?a niaoeeo?/ii?
eaai?aoi?ii? ae?aaiinoeee A?E-?ioaeoe??/NI?Aeo a ?ioi?iaoe?eiiio
caaacia/aii? ai?aeai?ieia?/iiai iaaeyaeo, ? aecia/aiith no?aoaa?? ?
oaeoeee ?o canoinoaaiiy a caeaaeiino? a?ae eiie?aoii? ai?aeai?/ii?
neooaoe??.

Iieacaii, ui aeey aaeaeaaoii? ai?aeai?ieia?/ii? ioe?iee ?acoeueoao?a
na?ieia?/iiai ne?ei?iao aieiaio ?ieue a?ae?a?a? aea?? no?aoaa??
?ioiiae?aaiinoeee o a?aeiia?aeiino? aei ??aiy ?iciianthaeaeaiiy
A?E-?ioaeoe?? a eiie?aoiiio ?aa?ii? aai na?aae iaaieo a?oi ianaeaiiy oa
iaoe ianoaaeaiiy. ?ic?iaeai? iaoeia? i?aeoiaee aei canoinoaaiiy oeeo
no?aoaa?e a Oe?a?i?.

Aaeineiiaeaia ?ioi?iaoe?eia i?aenenoaia ai?aeai?ieia?/iiai iaaeyaeo ca
A?E-?ioaeoe??th.

Eeth/ia? neiaa: A?E-?ioaeoe?y/NI?Ae, ai?aeai?ieia?/iee iaaeyae,
niaoeeo?/ia ?ioiiae?aaiinoeea, na?ieia?/iee ne?ei?ia, ?ioi?iaoe?eia
i?aenenoaia.

Na?aaaaa O.A. Niaoeeoe/aneay eiioiiaeeaaiinoeea a nenoaia
yieaeaieieiae/aneiai iaaeci?a ca AE*-eioaeoeeae.- ?oeiienue.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo
iaoe ii niaoeeaeueiinoe 14.02.02 — yieaeaieieiaey. —
Iao/ii-enneaaeiaaoaeueneee einoeooo yieaeaieieiaee e eioaeoeeiiiuo
aieaciae ei. E.A.A?iiaoaaneiai, Eeaa, 1998.

Aeenna?oaoeey iinayuaia eco/aieth ?iee nia?aiaiiuo iaoiaeia
niaoeeoe/aneie eiioiiaeeaaiinoeee AE*-eioaeoeee/NIEAea a
eioi?iaoeeiiiii iaania/aiee yieaeaieieiae/aneiai iaaeci?a, e
ii?aaeaeaieth no?aoaaee e oaeoeee eo i?eiaiaiey a caaeneiinoe io
eiie?aoiie yieaeaie/aneie neooaoeee.

Iieacaii, /oi aeey aaeaeaaoiie yieaeaieieiae/aneie ioeaiee
?acoeueoaoia na?ieiae/aneiai ne?eieiaa aeaaioth ?ieue ea?aao auai?
no?aoaaee eiioiiaeeaaiinoeee a niioaaonoaee n o?iaiai ?ani?ino?aiaiey
AE*-eioaeoeee a eiie?aoiii ?aaeiia eee n?aaee ii?aaeaeaiiuo a?oii
ianaeaiey e oeaeueth ianeaaeiaaiey. ?ac?aaioaiu iao/iua iiaeoiaeu e
i?eiaiaieth yoeo no?aoaaee a Oe?aeia.

Oniaa?oainoaiaaia eioi?iaoeeiiiay iiaenenoaia
yieaeaieieiae/aneiai iaaeci?a ca AE*-eioaeoeeae.

Eeth/aaua neiaa: AE*-eioaeoeey/NIEAe, yieaeaieieiae/aneee iaaeci?,
niaoeeoe/aneay eiioiiaeeaaiinoeea, na?ieiae/aneee ne?eieia,
eioi?iaoeeiiiay iiaenenoaia.

Sergeyeva T.A. Specific immunodiagnosis in system of epidemiological
surveillance on HIV-infection. — Manuscript.

Thesis for a degree of candidate of medical science by speciality
14.02.02 — epidemiology. Lev Gromashevsky Scientific Research Institute
of Epidemiology and Infectious Diseases, Kyiv, 1998.

Thesis is devoted on study of role of modern methods on specific
immunodiagnosis of HIV-infection/AIDS on information providing of
epidemiological surveillance and determination strategy and
tactics of their application on dependence from concrete epidemic
situation.

It is shown that for an adequate epidemiological evaluation of results
on serological screening the main role plays a choice on strategy of
immunodiagnosis in accordance with level of surveillance of
HIV-infection in concrete region among definite groups of population and
an aim of examination. Scientific approaches to application of these
strategies in Ukraine are developed.

Information subsystem of epidemiological surveillance on HIV-infection
is advanced.

Key words: HIV-infection/AIDS, epidemiological surveillance, specific
immunodiagnosis, serological screening, information subsystem.

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