.

Серцево-судинні розлади у хворих на лептоспіроз і методи їх корекції: Автореф. дис… канд. мед. наук / В.Ф. Пюрик, Київ. НДІ епідеміології та інфекц.

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I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

EE?ANUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO AI?AeAI?IEIA?? OA
?IOAEOe?EIEO OAI?IA

?iai? E.A.A?iiaoaanueeiai

OAeE 616.986.7+616.11+612.014.471

Ith?ee Aaeaioeia Oaaei??aia

NA?OeAAI-NOAeEII? ?ICEAAeE O OAI?EO IA EAIOINI??IC

? IAOIAeE ?O EI?AEOe??

14.01.13. – ?ioaeoe?ei? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1999

aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia ia eaoaae?? ?ioaeoe?eieo oai?ia Iaaii-O?aie?anueei?
aea?aeaaii? iaaee/ii? aeaaeai??

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani? Aiaaeai

Ieeieaeiae/ Aeeeee, caa?aeoaa/ eaoaae?e

?ioaeoe?eieo oai?ia Iaaii-O?aie?anueei?

aea?aeaaii? iaaee/ii? aeaaeai??.

Iaoeiaee eiinoeueoaio: aeieoi? iaaee/ieo iaoe, i?ioani? Ethaiie?

Aieiaeeie?iae/ Aeooei,caa?aeoaa/
eaoaae?e oa?ai??

oaeoeueoaoo i?neyaeeieiiii? ina?oe

Iaaii-O?aie?anueei? aea?aeaaii?
iaaee/ii? aeaaeai??.

Io?oe?ei? iiiiaioe: caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie, aeieoi?

iaaee/ieo iaoe, i?ioani? Ieoaeei
Aioiiiae/

Aiae?ae/ei, caa?aeoaa/ eaoaae?e
?ioaeoe?eieo oai?ia

Oa?iii?euenueei? iaaee/ii? aeaaeai??
?i. ?. ss.

Ai?aa/aanueeiai

eaiaeeaeao iaaee/ieo iaoe, i?ioani?
Aiae??e

Ieeieaeiae/ Nieie,

caa?aeoaa/ eaoaae?e ?ioaeoe?eieo
oai?ia Aoeiaeinueei?

iaaee/ii? aeaaeai??

I?ia?aeia i?aai?caoe?y: Euea?anueeee iaaee/iee oi?aa?neoao ?i. Aeaieea
Aaeeoeueeiai

Caoeno a?aeaoaeaoueny “ 31 ” aa?aciy 1999 ?ieo i 14-00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.614.01. i?e
Ee?anueeiio iaoeiai-aeine?aeiiio ?inoeooo? ai?aeai?ieia?? oa ?oaeoe?eieo
oai?ia ?i. E. A. A?iiaoaanueeiai IIC Oe?a?ie ( 252150, i. Ee?a, aoe.
N?/iaaiai iianoaiiy, 23).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Ee?anueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ai?aeaiieia?? oa ?oaeoe?eieo oai?ia ?i.
E. A. A?iiaoaanueeiai IIC Oe?a?ie.

Aaoi?aoa?ao ?ic?neaii “ 24 “ ethoiai 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe A.Ae.
Aiae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. I?iaeaia eaioinii?ico a Oe?a?ii iaaoaa? ana
aieueoiai cia/aiiy. Oey iioaeoeiy ? iae?iciianthaeaeaiioith
i?e?iaeii-ina?aaeeiaith oai?iaith ic ae?aaeaiith oaiaeaioei?th aei ?inoo
caoai?thaaiinoi (A.E.Oa?thiia, 1989; ?.I.Aa?ianianueea ? ni?aaao.,
1996). Ca iieacieeii eaoaeueiinoi oa nooiaiai aaaeeinoi eaioinii?ic
caeia? iaeia c ia?oeo iinoeue a iioaeoeieiie iaoieiai?.
Eaoaeueiinoue i?e eaioinii?ic? a inoaiii ?iee aeinyaa? 10-11 %
(?.I.Eioiaa, 1989; A.I.Eiiae?aoaiei, 1990).

O iioe?aii? eaioini??ico a ?aaii-O?aie?anuee?e iaeano? iaaio ?ieue
a?ae?a?aee ci?ie i?e?iaeieo oiia: noai?aiiy “oaieiai” Ao?ooeinueeiai
aiaeieieua, iai?iaeoiai? iae?i?aoeai? ?iaioe, caa?oaeiaiiy aiaeieieu
noieaie oaa?eiieoeueeeo oa?i oiui. Ana oea ni?eyei aeieeiaiith
aeoeaiiai ina?aaeeo eaioini??ico, iioe?aiith oe??? ?ioaeoe?? ia aanue
aanaei Aei?no?a oa oei??iaiith ?? a eiai ieceiieo ?aeiiao (A.I.Canooa ?
ni?aaao, 1993).

Ca aeaieie TH.A. Aa?ooaeia ? ni?aaao. (1983), Furner L. (1990),
I.A.Aiae?ae/eia ? ni?aaao (1994), TH.I.Ai?n?iiai?, A.?.Iaoyoa (1996),
i?e eaioini??ic? iae/ano?oa ?icaeaathoueny oae? oneeaaeiaiiy, ye aino?a
ie?eiai-ia/?ieiaa iaaeinoaoi?noue, aeenai?iiaaia aioo??oiueinoaeeiia
cn?aeaiiy e?ia?, eaaaiaaa iaaeinoaoi?noue. A oie aea /an ? ?yae
ianenoaiaoeciaaieo iaoeiaeo iia?aeiieaiue i?i oa, ui o oai?eo ia
eaioini??ic niinoa??aaeeny cia/i? ci?ie a na?oeaai-noaeeii?e nenoai?.
Oe? ci?ie i?iyaeythoueny iiieaeaiei a?oa??aeueiei oeneii, ?icaeoeii
eieaioi?aeieo noai?a, a?aaeeea?ae??th, aeee?io??th ioeueno (A.O.O?ieia,
1987; ss.N.Ioieaae/-Ae?aiaio, 1990; Farr R.W., 1995). ?io? aaoi?e
aeacothoue ia oa, ui ??cei ae?aaeai? ci?ie na?oeaai-noaeeiii? nenoaie ia
? /anoeie (A.N.E?eoaiei, 1985). Ie?ai? iia?aeiieaiiy i?aee?aneththoue,
ui o oai?eo ia eaioini??ic ?icaeaathoueny ii?ooaiiy ae?yeueiino?
i?iea?aeo, na?oeaaiai ?eoio, i?iyae na?oeaai-noaeeiii? iaaeinoaoiino?,
aea oe? oaeoe ia io?eiaee iaeaaeiiai a?aeia?aaeaiiy a e?oa?aoo??
(A.E.Eanieeia, E.I.Oiea?aae/, 1982; A.I.Ooaaeiaa, 1990).

A?eueo?noue no/anieo aaoi??a aaaaeathoue, ui ii?ooaiiy i?e?ioee?eoeyoe??
? aaaeeeaei iaoiaaiaoe/iei eaioethaii o ?icaeoeo ie?eiai-ia/?ieiai?,
na?oeaai-noaeeiii?, aino?i? aeeoaeueii? iaaeinoaoiino? (J.A.Shulman,
1990; C.A.Aa?acianueea ? ni?aaao., 1994). Iacaaaeath/e ia oa, ui a
iaoiaaiac? eaioini??ico ii?ooaiiyi i?e?ioee?eoeyoe?? a?aeaiaeyoue
nooo?aa i?noea, oea ieoaiiy inoaoi/ii ia aea/aia. Ia ai?iaiaai? oanoe,
ye? aeaaaee a iiaeeea?noue aeyaeoe ?aii? ci?ie i?e?ioee?eoeyoe??.

Aaii?aa?/iee neiae?ii ia??aeei oneeaaeith? ia?aa?a caoai?thaaiiy ? iiaea
aooe i?e/eiith eaoaeueiiai iane?aeeo i?e eaioini??ic? (TH.A.Aa?ooaei,
A.I.Aeiia?aaeiaa, 1988; C.Ae.Eiiiiaa, A.I.Aaeye, 1990). ?ieue aaiinoaco
i?e eaioini??ic? aea/aia iaaeinoaoiuei, iniaeeai oea noino?oueny noaio
noaeeiii? eaiee aaiinoaco.

A c’ayceo c oei, ui a ?yae? i?aai?a ? nenoai aeieeathoue iaoieia?/i?
ci?ie, ye? ia onoaathoueny i?ae aieeaii ao?io?iiiiai e?eoaaiiy
(aioea?ioeee, i?ioeeaioini??iciee ?ioiiaeiaoe?i), iaiao?aeiei ?
i?ecia/aiiy iaoiaaiaoe/ii? ? neiioiiaoe/ii? oa?ai?? (I.A.Aaneeue?a,
1997).

Iacaaaeath/e ia ?yae iiaeo iaaeeeaiaioicieo i?aia?ao?a, aei oeueiai /ano
ia ?ic?iaeai? caoiaee iiia?aaeaeaiiy ci?i a nenoai? aaiinoaco, ?iaio?
i?iea?aeo, i?e?ioee?eoeyoe?? (O.I.Coaee, 1993; I.E.Ee?e/aiei, 1997).

Iaaaaeai? oaeoe na?ae/aoue i?i ?nioth/? i?iaeaie ae?aaiinoeee
oneeaaeiaiue eaioini??ico, ui ? i?e/eiith o?eaaeiai ia?aaoaaiiy oai?eo
a noaoe?iia??. A?aoiaoth/e aeuaneacaia, aea/aiiy na?oeaai-noaeeiieo ?
i?e?ioee?eoeyoi?ieo ii?ooaiue, ci?i a nenoai? aaiinoaco, a oaeiae
?ic?iaea iaoiae?a ?o onoiaiiy o oai?eo ia eaioini??ic ? aeooaeueieie.

Caycie ?iaioe c iaoeiaeie i?ia?aiaie, oaiaie.

Aeena?oaoe?eia ?iaioa aeeiiaia ca?aeii ieaio iaoeiai-aeine?aeieo ?ia?o
?aaii-O?aie?anueei? aea?aeaaii? iaaee/ii? aeaaeai??, caoaa?aeaeaiiio IIC
Oe?a?ie, ? ? o?aaiaioii iaoeiai? ?iaioe eaoaae?e ?ioaeoe?eieo oai?ia ia
oaio: “Aioa?ini?aoe?y i?e e?eoaaii? a??oniiai aaiaoeoo, eaioini??ico ?
aano?iaioa?ieie?oo” ?EA 01002015 ?.

Iaoa aeine?aeaeaiiy: aeyaeaiiy iniaeeainoae oa caeiiii??iinoae o?aaeaiue
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioini??ic ? ?ic?iaea ia oe?e
iniia? iaoiae?a ?o ei?aeoe??.

Aeey aeinyaiaiiy iaoe aoee iinoaaeaii ianooiii caaea/?:

1. Aeine?aeeoe a aeeiai?oe? ee?i?/i? i?iyae o?aaeaiue i?iea?aea oa
ii?ooaiiy oeaio?aeueii? aaiiaeeiai?ee o oai?eo ia eaioini??ic c
aeei?enoaiiyi aoiea?ae?ia?ao?? oa aeaeo?iea?ae?ia?ao??.

2. Aea/eoe noai ?aa?iiaeueiiai e?iaiia?ao oa i?e?ioee?eoeyoe?? o oai?eo
ia eaioini??ic ca aeiiiiiaith ?aiaacia?ao??, eii’thieoeaaeueii?
a?ii?e?ineii?? oa iaoia?noieia?/ieo aeine?aeaeaiue.

3. Aea/eoe noai noaeeiiiai oa o?iiaioeeoa?iiai aaiinoaco, aeine?aeeoe
iieacieee cn?aeaeueii? nenoaie e?ia? o oai?eo ia eaioinii?ic.

4. Ia i?aenoaa? io?eiaieo aeaieo ?ic?iaeoe iaoiaee ei?aeoe?? ii?ooaiue
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioinii?ic oeyoii aeeth/aiiy
aei eiiieaeniiai e?eoaaiiy aoaiceeaoo iao?ith oa ?eaieneio.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a:

– aia?oa, ia i?aenoaa? ?icoe?aiiai ee?i?/iiai ianoaaeaiiy oai?eo ia
eaioini??ic, ocaaaeueiaii oeie o?aaeaiue i?iea?aea, aecia/aii ?o /anoioo
oa caeaaei?noue a?ae iniaeeainoae ia?aa?ao caoai?thaaiiy;

– iaea?aeaii iia? aeai? i?i iaoiaaiac ?iceaae?a i?e?ioee?eoeyoe?? i?e
eaioini??ic?, iaoiaee ?o aeyaeaiiy a ee?i?/ieo oiiaao ;

– io?eiai? aeai? i?i iniaeeaino? ii?ooaiiy aaiinoaco i?e eaioini??ic?
aeicaieeee ?ic?iaeoe ?o iioiaaiaoe/io aeeoa?aioe?aoe?th (noaeeiia,
o?iiaioeeoa?ia eaiee);

– aeei?enoaiee eiiieaeniee i?aeo?ae aei aea/aiiy noaio
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioini??ic c iaeii/aniei
aeine?aeaeaiiyi noaio i?iea?aea, oeaio?aeueii? aaiiaeeiai?ee,
?aa?iiaeueiiai e?iaiia?ao, i?e?ioee?eoeyoe?? oa nenoaie aaiinoaco;

– aia?oa iaa?oioiaaii aeei?enoaiiy a eiiieaen? e?eoaaeueieo caoiae?a i?e
eaioini??ic? ?eaieneio – i?aia?aoo, ui iie?auo? iaoaaie?ci ?
aia?aiaeeiai?eo i?iea?aeo oa aoaiceeaoo iao??th – caniao, yeee
ii?iae?co? ii?ooai? noaeeiio oa ee?oeiio eaiee aaiinoaco.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a:

– ?aeiiaiaeiaaii eiiieaenia ianoaaeaiiy na?oeaai? ae?yeueiino? o oai?eo
ia eaioini??ic ?c a?aooaaiiyi ??ciiaeae?a ?? ii?ooaiue;

– cai?iiiiiaaii aoaeoeai? oa aeinooii? aeey i?aeoe/ii? iaaeeoeeie
iaoiaee aecia/aiiy noaio ?aa?iiaeueiiai e?iaiia?ao, i?e?ioee?eoeyoe?? oa
aaiinoaco o oai?eo ia eaioini??ic;

– ?ic?iaeaii iaoiaee ei?aeoe?? o?aaeaiue i?iea?aeo, ii?ooaiue
i?e?ioee?eoeyoe?? oa aaiinoaco o oai?eo ia eaioini??ic oeyoii
aeeth/aiiy aei eiia?iiaaiiai e?eoaaiiy ?eaieneio oa aoaiceeaoo iao??th;

– aeinooii?noue, aeiiii?/i?noue, a?aenooi?noue iia?/ieo ?aaeoe?e
aecia/a? ia?niaeoeai?noue aeei?enoaiiy ?ic?iaeaii? iaoiaeeee e?eoaaiiy
oai?eo ia eaioini??ic c na?aaeiueiaaaeeeie ? aaaeeeie oi?iaie;

– ?ic?iaeaia iaoiaeeea ei?aeoe?? ii?ooaiue ooieoe?e i?iea?aeo,
i?e?ioee?eoeyoe??, nenoaie aaiinoaco ai?iaaaeaeaia a ae?yeuei?noue ?yaeo
e?eoaaeueieo onoaiia: iinueea eeiii/ia iioaeoeieia eiea?iy i.
Iaaii-O?aieianuee, Eieiieenueea iioaeoeieia eiea?iy,
iioaeoeiei? aiaeaeieaiiy Ao?ooeinueei? IN*, Eaeonueeiai i
Aiai?iae/ainueeiai OII. Iaoa?iaee aeena?oaoei? aeei?enoiaothoueny a
iaa/aeueiiio i?ioeani ia eaoaae?ao iioaeoeieieo oai?ia c eo?nii
aiiaeaiiieiai?, oa?ai?? oaeoeueoaoo i?neyaeeieiiii? ina?oe, oa?iaeieiai?
Iaaii-O?aieianueei? aea?aeaaii? iaaee/ii? aeaaeaii?.

Iniaenoee aianie caeiaoaa/a. Aeeaae aaoi?a a io?eiaii? iaoeiaeo
?acoeueoao?a ? iniiaiei ? iieyaa? a aiae?c? e?oa?aoo?e, i?iaaaeaii? oa
ia?iaoe? ?acoeueoao?a ee?i?/ieo, eaai?aoi?ieo oa ?ino?oiaioaeueieo
aeine?aeaeaiue, noaoenoe/i?e ia?iaoe? iaoa??aeo, i?aeaioiaoe? iaoa??aeo
aei iioae?eoaaiiy. An? ?acoeueoaoe aeine?aeaeaiue, iaaaaeai? a
aeena?oaoe??, io?eiai? iniaenoi aaoi?ii.

Ai?iaaoe?y ?iaioe. Iniiai? oai?aoe/i? ? i?aeoe/i? iieiaeaiiy
aeena?oaoei? ii?eethaeiai? i iaaiai?aii ia iaeanieo iaoeiaeo
eiioa?aioeiyo iieiaeeo a/aieo-iaaeeeia oa niaoeiaeinoia
Iaaii-O?aieianueei? aea?aeaaii? iaaee/ii? aeaaeaii? (Iaaii-O?aieianuee,
1994, 1995); Iiaeia?iaeiiio Eii??ani Iieiaeeo A/aieo Oe?a?ioeia
(Iaaii-O?aieianuee, 1995); VI Eii??ani NOOEO (Iaeana, 1996);
Eiioa?aioei? ii iaaiaeeeaaeieo noaiao a iaaeeoeeii (Eueaia, 1997);
V c’?cae? ?ioaeoe?ii?no?a Oe?a?ie (Oa?iii?eue, 1998); ia
iaoeiai-i?aeoe/ieo eiioa?aioeiyo a/aieo oa niaoeiaeinoia iaeanoi
(Iaaii-O?aieianuee, 1996); caniaeaiiyo Iaaii-O?aieianueeiai iaeaniiai
iaoeiai-iaaee/iiai oiaa?enoaa iioaeoeiiiinoia (Iaaii-O?aieianuee,
1996, 1997).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 13 ?ia?o, a oiio
/ene? 4 noaoo? a oeaio?aeueieo oaoiaeo aeaeaiiyo (c ieo 1 in?aia),
ai?iaaaeaeaii ?aoe?iiae?caoi?nueeo i?iiiceoe?th ? 37/2326 a?ae
30.06.1997 ?., ca?a?no?iaaio ?aaii-O?aie?anueeith aea?aeaaiith
iaaee/iith aeaaeai??th.

Ianya ? no?oeoo?a aeena?oaoe??. Iaoa??aee aeena?oaoe?? aeeeaaeaii ia 170
noi??ieao, c ieo aeania oaeno caeia? 153 noi??iee. ?iaioa neeaaea?oueny
c anooio, iaeyaeo e?oa?aoo?e, ee?i?/ii? oa?aeoa?enoeee oai?eo ? iaoiae?a
ianoaaeaiiy, aeaio ?icae?e?a c ?acoeueoaoaie aeanieo aeine?aeaeaiue,
aiae?co ? ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiiy, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo aeei?enoaieo aeaea?ae. ?acoeueoaoe
aeine?aeaeaiiy aeeeaaeai? a 37 oaaeeoeyo, 17 ?enoieao, 3 aeieneao c
?noi??? oai?iae. Nienie aeei?enoaii? e?oa?aoo?e aeeth/a? 212 aeaea?ae.

INIIAIEE CI?NO

Ia’?eo ? iaoiaee ee?i?/iiai aeine?aeaeaiiy. ?iaioa a?oioo?oueny ia
ee?i?/iiio niinoa?aaeaii?, niaoe?aeueieo aeineiaeaeaiiyo ? e?eoaaii?
114 oai?eo ia eaioinii?ic, ui i?iaiaeeeinue c 1992 ii 1997 ?.?. ia aac?
i?nueei? ee?i?/ii? ?ioaeoe?eii? e?ea?i? i. Iaaii-O?aieianuee. Oai?? aoee
o a?oe? a?ae 15 aei 65 ?ie?a, ?c ieo /ieia?e?a – 78 (68,4 %), ae?iie –
36 (31,6 %). A?eueoo /anoeio (60,5 %) neeaee oai?i o aioei 31-50 ?ieia,
oiaoi iaei?aoeacaeaoi?oa a?oia ianaeaiiy. O 40 (46,3 %) oai?eo ia
eaioini??ic aoea ae?aaiinoiaaia aacaeiaoyie/ia, o 68 (59,7 %) –
aeiaoyie/ia oi?ie oai?iae. Ca ao?ieia?/iith no?oeoo?ith 71,9 % noaiiaea
eaioini??ic, aeeeeeaiee L. icterohaemorrhagiae.

I?e oi?ioaaii? a?oi i?iaiaeeee aea??eiaee i?aea?? oeiieia?/ieo oai?eo ca
aeeeth/aiiyi iaoe??io?a ?c noiooiueith iaoieia??th na?oeaai-noaeeiii?
nenoaie. Aeae?eai? a?oie aoee ni?anoaaeai? ca a?eii ? ni?aa?aeiioaiiyi
oai?eo ?c na?aaeiueiaaaeeei oa aaaeeei ia?aa?aii eaioini??ico.

O 30 i?aeoe/ii caei?iaeo aeiii??a, ni?anoaaeaieo ca a?eii ? noaooth,
i?iaaaeaii eiio?ieuei? eaai?aoi?i? oa ?ino?oiaioaeuei? aeine?aeaeaiiy.

On? oai?? aoee ianoaaeai? aei e?eoaaiiy, a ia??iae? ?iciaeo oai?iae
(7-10 aeaiue), oa ia??iae? ?aeiiaaeanoeaioe?? (17-20 aeaiue).

Aeey aeinyaiaiiy iinoaaeaii? iaoe ? ?ica’ycaiiy caaea/ aea?aii
a?aeiia?aeiee eiiieaen ee?i?ei-eaai?aoi?ieo iaoiae?a aeine?aeaeaiiy:

– aea/aiiy o oai?eo ia eaioini??ic ee?i?/ieo iniaeeainoae noaio
na?oeaai-noaeeiii? nenoaie c ?a?no?aoe??th ?o ia ea?oao ianoaaeaiiy ?
ianooiiei ii??aiyiiyi /aiaiiac, ia’?eoeaia ianoaaeaiiy/;

– aecia/aiiy ??aiy ?ioieneeaoe?eiiai neiae?iio (ne?ei?iaiaee iaoiae
aecia/aiiy iaioeae?a na?aaeiueiiieaeoey?ii? iane (N.A. Aaeaeo?iiia,
1983), eaeeioeeoa?iee ?iaeaen ?ioieneeaoe?? (ca oi?ioeith
ss.ss.Eaeueo-Eae?oa), aaiaoieia?/iee iieaciee ?ioieneeaoe?? (ca A.N.
Aaneeue?aei, 1994);

– aeaeo?iea?ae?ia?ao?/i? ianoaaeaiiy i?iaiaeeee c aeiiiiiaith
oanoeeaiaeueiiai aeaeo?iea?ae?ia?aoa ”Aeei?” a iniiaieo ? aeiaeaoeiaeo
a?aeaaaeaiiyo;

– iieacieee oeaio?aeueii? aaiiaeeiai?ee ? nei?ioeeao ooieoe?th i?iea?aeo
aea/aee iaoiaeii aoiea?ae?ia?ao?? ca aeiiiiiaith aia?aoo “Niiineii-30”,
yeee i?aoethaaa a I-?aaeei?, ei?enooth/enue iieacieeaie cai?iiiiiaaieie
A.A.Ca?aoeueeei (1979);

– iieacieee ?aiaaiaoia?ai oa ?aiaacia?ai aea/aee ca aeiiiiiaith ?aia?aoa
?A-2-02 ?c caienii iieaciee?a ia oanoeeaiaeueiiio ea?ae?ia?ao? ca
iaoiaeeeith, cai?iiiiiaaiith O.Ae. Aeoeiaei (1986);

– aeine?aeaeaiiy noaio i?e?ioee?eoeyoe?? iaoiaeii eii’thieoeaaeueii?
a?ii?e?ineii?? aecia/aee ca A.N. Aieeiaei (1977);

– noai noaeeiii-o?iiaioeeoa?ii? ? eiaaoeyoe?eii? eaiie aaiinoaco aea/aee
ca iieacieeaie ?acenoaioiino? eai?ey??a (iaoiae
Eii/aeianueeiai-?oiiaey-Ea?aea, 1980).

E??i oiai aecia/aee:

– oaeoi? A?ee?a?aiaea ca Weiss a iiaeeo?eaoe?? I.A. Oeeaoeueiai? (1968);

– e?euee?noue o?iiaioeeo?a ca iaoiaeii ?. ?. Aeaiee?ia ? A.E.
E?eaeai?anueeiai (1967);

– aa?aaaoe?th o?iiaioeeo?a ca iaoiaeii Born a iiaeeo?eaoe?? A.I.
Aaeoaee (1968);

– aaeaaceai?noue o?iiaioeeo?a ca Salzman (1967);

– ai?no aioeo?iia?io ??? ca iaoiaeeeith Hensen, Loeliger a iiaeeo?eaoe??
E.I. Aeoaanueeiai (1978);

– noai nenoaie cn?aeaiiy e?ia? aiae?coaaee ca iieacieeaie eiaaoeia?ai;

– iaoiii?oieia?/i? aeine?aeaeaiiy aeeiiaii ca o?aaeeoe?eieie
iaoiaeeeaie.

Na?ieia?/ii oeo? aioeo?e a aeeiai?oe? caoai?thaaiiy aecia/aee ca
aeiiiiiaith ?aaeoe?? i?e?iaaethoeiaoe?? ia aac? eaai?aoi??? iniaeeai
iaaacia/ieo ?ioaeoe?e iaeanii? NAN.

Noaoenoe/io ia?iaeo io?eiaieo ?acoeueoaoia i?iaiaeeee ca aeiiiiiaith
iie?ieaeueeoeyoi?a “Aeaeo?iiiea IE-61” c aeei?enoaiiyi aiaeiiaiaeieo
i?ia?ai.

Oa?aeoa?enoeea ii?ooaiue na?oeaai-noaeeiii? nenoaie o oai?eo ia
eaioini??ic

A ?acoeueoao? aeine?aeaeaiiy aeyaeee, ui aaea a ii/aoeiaiio ia??iae?
caoai?thaaiiy o oai?eo ia eaioini??ic c na?aaeiueiaaaeeith oa aaaeeith
oi?iaie niinoa??aaeenue noa’?eoeai? ? ia’?eoeai? i?iyae o?aaeaiue
na?oeaai-noaeeiii? nenoaie (oaae. 1).

Oaaeeoey 1

Noa’?eoeai? ? ia’?eoeai? ee?i?/i? i?iyae ii?ooaiue na?oeaai-noaeeiii?
nenoaie a oai?eo ia eaioini??ic o ii/aoeiaiio ia??iae?

E?euee?noue oai?eo

Iciaee caoai?thaaiiy aacaeiaoyie/ia oi?ia, n=46 aeiaoyie/ia oi?ia, n=68

aan. % aan. %

Aie? a ae?eyioe? na?oey 15 32,6 31 48,5

A?ia?ai?y iaee//y 21 45,6 41 60,3

?i’?eoe?y noaeei neea? 24 52,2 60 88,2

E?iaiaeeeae a neea?o 18 39,1 33 48,5

Aaii?aa?/i? aeneiaiiy 16 34,8 31 45,6

I?aeaeuaia e?iaioi/ea?noue 12 26,1 23 33,8

?icoe?aiiy iaae na?oey 4 8,7 9 13,2

Nenoie?/iee ooi iaae aa?o?aeith na?oey 24 52,2 43 63,2

I?eaeooai?noue na?oeaaeo oii?a 33 71,7 62 91,2

A?aaeeea?ae?y 11 23,9 17 25,0

Oao?ea?ae?y 18 39,1 42 61,8

A?eoi?y 9 19,6 16 23,5

A?oa??aeueia a?iioii?y 39 84,8 61 89,7

O aeiaaeeo ?aiiuei? aini?oae?caoe?? /anoioa aeyaeaieo ci?i
na?oeaai-noaeeiii? nenoaie noaiiaeea 19,1 %. I?e aini?oae?caoe??
i?ney 6-8 aeiy caoai?thaaiiy niinoa??aaeinue ca?eueoaiiy e?eueeino?
o?aaeaiue na?oeaai-noaeeiii? nenoaie aei 54,5-75,0 %. .

Ia?inoaiiy ?ioieneeaoe?eiiai neiae?iio noi?iaiaeaeoaaeinue ?inoii
noa’?eoeaieo ? ia’?eoeaieo ci?i c aieo na?oeaai-noaeeiii? nenoaie o
oai?eo ia eaioini??ic. Iaea?eueo /anoi o?aaeaiiy niinoa??aaeenue o
oai?eo c III nooiaiai ?ioieneeaoe?eiiai neiae?iio (68,2 %).

Ii?ooaiiy i?iea?aeo, eiai noaeeiiiai ?onea iathoue oaciee oa?aeoa?.
A?ae eae?a?o cao?iiaiaaieo noaeei ? nooiaiy ieethc?? caeaaeeoue
iioe?ai?noue ? aeeaeia aaiiaeeiai?/ieo ? aeano?oeoeaieo ii?ooaiue a
noaeeiao, i?aaiao ? oeaieiao (I.A.I?eia/aiei ? ni?aaao., 1986).

I?e a?io?i?/iiio aeine?aeaeaii? aeyaeee aeinoia??ia i?aeaeuaiiy
aeoeaiino? oa?iaioo AnAO, ui oaeiae na?ae/eei i?i aoyaiaiiy a
iaoieia?/iee i?ioean na?oeaaiai i’yca (p0,05).

A?aei?/aii nooo?aee aieea cai?iiiiiaaiiai e?eoaaiiy ia ooieoe?th
?aiaeueii? nenoaie. Oae, o oai?eo ?-A ee?i?/ii? a?oie ??aaiue e?aaoei?io
a ne?iaaooe? e?ia? cieceany aei 115±8 ieiieue/e (pTV6 – – – 10.0 9.1 3.8

Neioniaa a?eoi?y 21.4 14.3 11.1 25.0 18.2 11.5

Neioniaa oao?ea?ae?y 7.1 7.1 – 15.0 9.1 3.8

Neioniaa a?aaeeea?ae?y 14.2 7.1 – 15.0 9.1 7.7

Aeno?anenoie?y:

noi?aaaio?eeoey?ia 7.1 – – 10.0 9.1 3.8

oeoii/eiaa – – – 5.0 4.5 –

Aeieaaee:

aioo??oiueiia?aaena?aeia – – – 5.0 4.5 3.8

ao??iaaio?eeoey?ia 7.1 – – – – –

i?aeie io/ea A?na 7.1 7.1 – 10.0 9.1 3.8

Aiae?c iieaciee?a oeaio?aeueii? aaiiaeeiai?ee iieacaa, ui o oai?eo ia
eaioini??ic c a?ia?aeeiai?/iei oeiii e?iaiia?ao iieacieee ci?ithaaeenue
o cai?ioiueiio iai?yieo a cia/ii ei?ioo? oa?i?ie. Oae, /a?ac 7-10
aei?a e?eoaaiiy oaea?iee ? nenoie?/iee ?iaeaene eieeaaeenue a iaaeao
49,26-51,42 ie/i2 oa 3,19-3,33 e/oa./i2 a?aeiia?aeii (p

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