I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

EE?ANUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO AI?AeAI?IEIA?? OA
?IOAEOe?EIEO OAI?IA

?iai? E.A.A?iiaoaanueeiai

OAeE 616.986.7+616.11+612.014.471

Ith?ee Aaeaioeia Oaaei??aia

NA?OeAAI-NOAeEII? ?ICEAAeE O OAI?EO IA EAIOINI??IC

? IAOIAeE ?O EI?AEOe??

14.01.13. — ?ioaeoe?ei? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1999

aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia ia eaoaae?? ?ioaeoe?eieo oai?ia Iaaii-O?aie?anueei?
aea?aeaaii? iaaee/ii? aeaaeai??

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani? Aiaaeai

Ieeieaeiae/ Aeeeee, caa?aeoaa/ eaoaae?e

?ioaeoe?eieo oai?ia Iaaii-O?aie?anueei?

aea?aeaaii? iaaee/ii? aeaaeai??.

Iaoeiaee eiinoeueoaio: aeieoi? iaaee/ieo iaoe, i?ioani? Ethaiie?

Aieiaeeie?iae/ Aeooei,caa?aeoaa/
eaoaae?e oa?ai??

oaeoeueoaoo i?neyaeeieiiii? ina?oe

Iaaii-O?aie?anueei? aea?aeaaii?
iaaee/ii? aeaaeai??.

Io?oe?ei? iiiiaioe: caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie, aeieoi?

iaaee/ieo iaoe, i?ioani? Ieoaeei
Aioiiiae/

Aiae?ae/ei, caa?aeoaa/ eaoaae?e
?ioaeoe?eieo oai?ia

Oa?iii?euenueei? iaaee/ii? aeaaeai??
?i. ?. ss.

Ai?aa/aanueeiai

eaiaeeaeao iaaee/ieo iaoe, i?ioani?
Aiae??e

Ieeieaeiae/ Nieie,

caa?aeoaa/ eaoaae?e ?ioaeoe?eieo
oai?ia Aoeiaeinueei?

iaaee/ii? aeaaeai??

I?ia?aeia i?aai?caoe?y: Euea?anueeee iaaee/iee oi?aa?neoao ?i. Aeaieea
Aaeeoeueeiai

Caoeno a?aeaoaeaoueny “ 31 ” aa?aciy 1999 ?ieo i 14-00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.614.01. i?e
Ee?anueeiio iaoeiai-aeine?aeiiio ?inoeooo? ai?aeai?ieia?? oa ?oaeoe?eieo
oai?ia ?i. E. A. A?iiaoaanueeiai IIC Oe?a?ie ( 252150, i. Ee?a, aoe.
N?/iaaiai iianoaiiy, 23).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Ee?anueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ai?aeaiieia?? oa ?oaeoe?eieo oai?ia ?i.
E. A. A?iiaoaanueeiai IIC Oe?a?ie.

Aaoi?aoa?ao ?ic?neaii “ 24 “ ethoiai 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe A.Ae.
Aiae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. I?iaeaia eaioinii?ico a Oe?a?ii iaaoaa? ana
aieueoiai cia/aiiy. Oey iioaeoeiy ? iae?iciianthaeaeaiioith
i?e?iaeii-ina?aaeeiaith oai?iaith ic ae?aaeaiith oaiaeaioei?th aei ?inoo
caoai?thaaiinoi (A.E.Oa?thiia, 1989; ?.I.Aa?ianianueea ? ni?aaao.,
1996). Ca iieacieeii eaoaeueiinoi oa nooiaiai aaaeeinoi eaioinii?ic
caeia? iaeia c ia?oeo iinoeue a iioaeoeieiie iaoieiai?.
Eaoaeueiinoue i?e eaioinii?ic? a inoaiii ?iee aeinyaa? 10-11 %
(?.I.Eioiaa, 1989; A.I.Eiiae?aoaiei, 1990).

O iioe?aii? eaioini??ico a ?aaii-O?aie?anuee?e iaeano? iaaio ?ieue
a?ae?a?aee ci?ie i?e?iaeieo oiia: noai?aiiy «oaieiai» Ao?ooeinueeiai
aiaeieieua, iai?iaeoiai? iae?i?aoeai? ?iaioe, caa?oaeiaiiy aiaeieieu
noieaie oaa?eiieoeueeeo oa?i oiui. Ana oea ni?eyei aeieeiaiith
aeoeaiiai ina?aaeeo eaioini??ico, iioe?aiith oe??? ?ioaeoe?? ia aanue
aanaei Aei?no?a oa oei??iaiith ?? a eiai ieceiieo ?aeiiao (A.I.Canooa ?
ni?aaao, 1993).

Ca aeaieie TH.A. Aa?ooaeia ? ni?aaao. (1983), Furner L. (1990),
I.A.Aiae?ae/eia ? ni?aaao (1994), TH.I.Ai?n?iiai?, A.?.Iaoyoa (1996),
i?e eaioini??ic? iae/ano?oa ?icaeaathoueny oae? oneeaaeiaiiy, ye aino?a
ie?eiai-ia/?ieiaa iaaeinoaoi?noue, aeenai?iiaaia aioo??oiueinoaeeiia
cn?aeaiiy e?ia?, eaaaiaaa iaaeinoaoi?noue. A oie aea /an ? ?yae
ianenoaiaoeciaaieo iaoeiaeo iia?aeiieaiue i?i oa, ui o oai?eo ia
eaioini??ic niinoa??aaeeny cia/i? ci?ie a na?oeaai-noaeeii?e nenoai?.
Oe? ci?ie i?iyaeythoueny iiieaeaiei a?oa??aeueiei oeneii, ?icaeoeii
eieaioi?aeieo noai?a, a?aaeeea?ae??th, aeee?io??th ioeueno (A.O.O?ieia,
1987; ss.N.Ioieaae/-Ae?aiaio, 1990; Farr R.W., 1995). ?io? aaoi?e
aeacothoue ia oa, ui ??cei ae?aaeai? ci?ie na?oeaai-noaeeiii? nenoaie ia
? /anoeie (A.N.E?eoaiei, 1985). Ie?ai? iia?aeiieaiiy i?aee?aneththoue,
ui o oai?eo ia eaioini??ic ?icaeaathoueny ii?ooaiiy ae?yeueiino?
i?iea?aeo, na?oeaaiai ?eoio, i?iyae na?oeaai-noaeeiii? iaaeinoaoiino?,
aea oe? oaeoe ia io?eiaee iaeaaeiiai a?aeia?aaeaiiy a e?oa?aoo??
(A.E.Eanieeia, E.I.Oiea?aae/, 1982; A.I.Ooaaeiaa, 1990).

A?eueo?noue no/anieo aaoi??a aaaaeathoue, ui ii?ooaiiy i?e?ioee?eoeyoe??
? aaaeeeaei iaoiaaiaoe/iei eaioethaii o ?icaeoeo ie?eiai-ia/?ieiai?,
na?oeaai-noaeeiii?, aino?i? aeeoaeueii? iaaeinoaoiino? (J.A.Shulman,
1990; C.A.Aa?acianueea ? ni?aaao., 1994). Iacaaaeath/e ia oa, ui a
iaoiaaiac? eaioini??ico ii?ooaiiyi i?e?ioee?eoeyoe?? a?aeaiaeyoue
nooo?aa i?noea, oea ieoaiiy inoaoi/ii ia aea/aia. Ia ai?iaiaai? oanoe,
ye? aeaaaee a iiaeeea?noue aeyaeoe ?aii? ci?ie i?e?ioee?eoeyoe??.

Aaii?aa?/iee neiae?ii ia??aeei oneeaaeith? ia?aa?a caoai?thaaiiy ? iiaea
aooe i?e/eiith eaoaeueiiai iane?aeeo i?e eaioini??ic? (TH.A.Aa?ooaei,
A.I.Aeiia?aaeiaa, 1988; C.Ae.Eiiiiaa, A.I.Aaeye, 1990). ?ieue aaiinoaco
i?e eaioini??ic? aea/aia iaaeinoaoiuei, iniaeeai oea noino?oueny noaio
noaeeiii? eaiee aaiinoaco.

A c’ayceo c oei, ui a ?yae? i?aai?a ? nenoai aeieeathoue iaoieia?/i?
ci?ie, ye? ia onoaathoueny i?ae aieeaii ao?io?iiiiai e?eoaaiiy
(aioea?ioeee, i?ioeeaioini??iciee ?ioiiaeiaoe?i), iaiao?aeiei ?
i?ecia/aiiy iaoiaaiaoe/ii? ? neiioiiaoe/ii? oa?ai?? (I.A.Aaneeue?a,
1997).

Iacaaaeath/e ia ?yae iiaeo iaaeeeaiaioicieo i?aia?ao?a, aei oeueiai /ano
ia ?ic?iaeai? caoiaee iiia?aaeaeaiiy ci?i a nenoai? aaiinoaco, ?iaio?
i?iea?aeo, i?e?ioee?eoeyoe?? (O.I.Coaee, 1993; I.E.Ee?e/aiei, 1997).

Iaaaaeai? oaeoe na?ae/aoue i?i ?nioth/? i?iaeaie ae?aaiinoeee
oneeaaeiaiue eaioini??ico, ui ? i?e/eiith o?eaaeiai ia?aaoaaiiy oai?eo
a noaoe?iia??. A?aoiaoth/e aeuaneacaia, aea/aiiy na?oeaai-noaeeiieo ?
i?e?ioee?eoeyoi?ieo ii?ooaiue, ci?i a nenoai? aaiinoaco, a oaeiae
?ic?iaea iaoiae?a ?o onoiaiiy o oai?eo ia eaioini??ic ? aeooaeueieie.

Caycie ?iaioe c iaoeiaeie i?ia?aiaie, oaiaie.

Aeena?oaoe?eia ?iaioa aeeiiaia ca?aeii ieaio iaoeiai-aeine?aeieo ?ia?o
?aaii-O?aie?anueei? aea?aeaaii? iaaee/ii? aeaaeai??, caoaa?aeaeaiiio IIC
Oe?a?ie, ? ? o?aaiaioii iaoeiai? ?iaioe eaoaae?e ?ioaeoe?eieo oai?ia ia
oaio: “Aioa?ini?aoe?y i?e e?eoaaii? a??oniiai aaiaoeoo, eaioini??ico ?
aano?iaioa?ieie?oo” ?EA 01002015 ?.

Iaoa aeine?aeaeaiiy: aeyaeaiiy iniaeeainoae oa caeiiii??iinoae o?aaeaiue
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioini??ic ? ?ic?iaea ia oe?e
iniia? iaoiae?a ?o ei?aeoe??.

Aeey aeinyaiaiiy iaoe aoee iinoaaeaii ianooiii caaea/?:

1. Aeine?aeeoe a aeeiai?oe? ee?i?/i? i?iyae o?aaeaiue i?iea?aea oa
ii?ooaiiy oeaio?aeueii? aaiiaeeiai?ee o oai?eo ia eaioini??ic c
aeei?enoaiiyi aoiea?ae?ia?ao?? oa aeaeo?iea?ae?ia?ao??.

2. Aea/eoe noai ?aa?iiaeueiiai e?iaiia?ao oa i?e?ioee?eoeyoe?? o oai?eo
ia eaioini??ic ca aeiiiiiaith ?aiaacia?ao??, eii’thieoeaaeueii?
a?ii?e?ineii?? oa iaoia?noieia?/ieo aeine?aeaeaiue.

3. Aea/eoe noai noaeeiiiai oa o?iiaioeeoa?iiai aaiinoaco, aeine?aeeoe
iieacieee cn?aeaeueii? nenoaie e?ia? o oai?eo ia eaioinii?ic.

4. Ia i?aenoaa? io?eiaieo aeaieo ?ic?iaeoe iaoiaee ei?aeoe?? ii?ooaiue
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioinii?ic oeyoii aeeth/aiiy
aei eiiieaeniiai e?eoaaiiy aoaiceeaoo iao?ith oa ?eaieneio.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a:

— aia?oa, ia i?aenoaa? ?icoe?aiiai ee?i?/iiai ianoaaeaiiy oai?eo ia
eaioini??ic, ocaaaeueiaii oeie o?aaeaiue i?iea?aea, aecia/aii ?o /anoioo
oa caeaaei?noue a?ae iniaeeainoae ia?aa?ao caoai?thaaiiy;

— iaea?aeaii iia? aeai? i?i iaoiaaiac ?iceaae?a i?e?ioee?eoeyoe?? i?e
eaioini??ic?, iaoiaee ?o aeyaeaiiy a ee?i?/ieo oiiaao ;

— io?eiai? aeai? i?i iniaeeaino? ii?ooaiiy aaiinoaco i?e eaioini??ic?
aeicaieeee ?ic?iaeoe ?o iioiaaiaoe/io aeeoa?aioe?aoe?th (noaeeiia,
o?iiaioeeoa?ia eaiee);

— aeei?enoaiee eiiieaeniee i?aeo?ae aei aea/aiiy noaio
na?oeaai-noaeeiii? nenoaie o oai?eo ia eaioini??ic c iaeii/aniei
aeine?aeaeaiiyi noaio i?iea?aea, oeaio?aeueii? aaiiaeeiai?ee,
?aa?iiaeueiiai e?iaiia?ao, i?e?ioee?eoeyoe?? oa nenoaie aaiinoaco;

— aia?oa iaa?oioiaaii aeei?enoaiiy a eiiieaen? e?eoaaeueieo caoiae?a i?e
eaioini??ic? ?eaieneio — i?aia?aoo, ui iie?auo? iaoaaie?ci ?
aia?aiaeeiai?eo i?iea?aeo oa aoaiceeaoo iao??th — caniao, yeee
ii?iae?co? ii?ooai? noaeeiio oa ee?oeiio eaiee aaiinoaco.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a:

— ?aeiiaiaeiaaii eiiieaenia ianoaaeaiiy na?oeaai? ae?yeueiino? o oai?eo
ia eaioini??ic ?c a?aooaaiiyi ??ciiaeae?a ?? ii?ooaiue;

— cai?iiiiiaaii aoaeoeai? oa aeinooii? aeey i?aeoe/ii? iaaeeoeeie
iaoiaee aecia/aiiy noaio ?aa?iiaeueiiai e?iaiia?ao, i?e?ioee?eoeyoe?? oa
aaiinoaco o oai?eo ia eaioini??ic;

— ?ic?iaeaii iaoiaee ei?aeoe?? o?aaeaiue i?iea?aeo, ii?ooaiue
i?e?ioee?eoeyoe?? oa aaiinoaco o oai?eo ia eaioini??ic oeyoii
aeeth/aiiy aei eiia?iiaaiiai e?eoaaiiy ?eaieneio oa aoaiceeaoo iao??th;

— aeinooii?noue, aeiiii?/i?noue, a?aenooi?noue iia?/ieo ?aaeoe?e
aecia/a? ia?niaeoeai?noue aeei?enoaiiy ?ic?iaeaii? iaoiaeeee e?eoaaiiy
oai?eo ia eaioini??ic c na?aaeiueiaaaeeeie ? aaaeeeie oi?iaie;

— ?ic?iaeaia iaoiaeeea ei?aeoe?? ii?ooaiue ooieoe?e i?iea?aeo,
i?e?ioee?eoeyoe??, nenoaie aaiinoaco ai?iaaaeaeaia a ae?yeuei?noue ?yaeo
e?eoaaeueieo onoaiia: iinueea eeiii/ia iioaeoeieia eiea?iy i.
Iaaii-O?aieianuee, Eieiieenueea iioaeoeieia eiea?iy,
iioaeoeiei? aiaeaeieaiiy Ao?ooeinueei? IN*, Eaeonueeiai i
Aiai?iae/ainueeiai OII. Iaoa?iaee aeena?oaoei? aeei?enoiaothoueny a
iaa/aeueiiio i?ioeani ia eaoaae?ao iioaeoeieieo oai?ia c eo?nii
aiiaeaiiieiai?, oa?ai?? oaeoeueoaoo i?neyaeeieiiii? ina?oe, oa?iaeieiai?
Iaaii-O?aieianueei? aea?aeaaii? iaaee/ii? aeaaeaii?.

Iniaenoee aianie caeiaoaa/a. Aeeaae aaoi?a a io?eiaii? iaoeiaeo
?acoeueoao?a ? iniiaiei ? iieyaa? a aiae?c? e?oa?aoo?e, i?iaaaeaii? oa
ia?iaoe? ?acoeueoao?a ee?i?/ieo, eaai?aoi?ieo oa ?ino?oiaioaeueieo
aeine?aeaeaiue, noaoenoe/i?e ia?iaoe? iaoa??aeo, i?aeaioiaoe? iaoa??aeo
aei iioae?eoaaiiy. An? ?acoeueoaoe aeine?aeaeaiue, iaaaaeai? a
aeena?oaoe??, io?eiai? iniaenoi aaoi?ii.

Ai?iaaoe?y ?iaioe. Iniiai? oai?aoe/i? ? i?aeoe/i? iieiaeaiiy
aeena?oaoei? ii?eethaeiai? i iaaiai?aii ia iaeanieo iaoeiaeo
eiioa?aioeiyo iieiaeeo a/aieo-iaaeeeia oa niaoeiaeinoia
Iaaii-O?aieianueei? aea?aeaaii? iaaee/ii? aeaaeaii? (Iaaii-O?aieianuee,
1994, 1995); Iiaeia?iaeiiio Eii??ani Iieiaeeo A/aieo Oe?a?ioeia
(Iaaii-O?aieianuee, 1995); VI Eii??ani NOOEO (Iaeana, 1996);
Eiioa?aioei? ii iaaiaeeeaaeieo noaiao a iaaeeoeeii (Eueaia, 1997);
V c’?cae? ?ioaeoe?ii?no?a Oe?a?ie (Oa?iii?eue, 1998); ia
iaoeiai-i?aeoe/ieo eiioa?aioeiyo a/aieo oa niaoeiaeinoia iaeanoi
(Iaaii-O?aieianuee, 1996); caniaeaiiyo Iaaii-O?aieianueeiai iaeaniiai
iaoeiai-iaaee/iiai oiaa?enoaa iioaeoeiiiinoia (Iaaii-O?aieianuee,
1996, 1997).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 13 ?ia?o, a oiio
/ene? 4 noaoo? a oeaio?aeueieo oaoiaeo aeaeaiiyo (c ieo 1 in?aia),
ai?iaaaeaeaii ?aoe?iiae?caoi?nueeo i?iiiceoe?th ? 37/2326 a?ae
30.06.1997 ?., ca?a?no?iaaio ?aaii-O?aie?anueeith aea?aeaaiith
iaaee/iith aeaaeai??th.

Ianya ? no?oeoo?a aeena?oaoe??. Iaoa??aee aeena?oaoe?? aeeeaaeaii ia 170
noi??ieao, c ieo aeania oaeno caeia? 153 noi??iee. ?iaioa neeaaea?oueny
c anooio, iaeyaeo e?oa?aoo?e, ee?i?/ii? oa?aeoa?enoeee oai?eo ? iaoiae?a
ianoaaeaiiy, aeaio ?icae?e?a c ?acoeueoaoaie aeanieo aeine?aeaeaiue,
aiae?co ? ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiiy, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo aeei?enoaieo aeaea?ae. ?acoeueoaoe
aeine?aeaeaiiy aeeeaaeai? a 37 oaaeeoeyo, 17 ?enoieao, 3 aeieneao c
?noi??? oai?iae. Nienie aeei?enoaii? e?oa?aoo?e aeeth/a? 212 aeaea?ae.

INIIAIEE CI?NO

Ia’?eo ? iaoiaee ee?i?/iiai aeine?aeaeaiiy. ?iaioa a?oioo?oueny ia
ee?i?/iiio niinoa?aaeaii?, niaoe?aeueieo aeineiaeaeaiiyo ? e?eoaaii?
114 oai?eo ia eaioinii?ic, ui i?iaiaeeeinue c 1992 ii 1997 ?.?. ia aac?
i?nueei? ee?i?/ii? ?ioaeoe?eii? e?ea?i? i. Iaaii-O?aieianuee. Oai?? aoee
o a?oe? a?ae 15 aei 65 ?ie?a, ?c ieo /ieia?e?a — 78 (68,4 %), ae?iie —
36 (31,6 %). A?eueoo /anoeio (60,5 %) neeaee oai?i o aioei 31-50 ?ieia,
oiaoi iaei?aoeacaeaoi?oa a?oia ianaeaiiy. O 40 (46,3 %) oai?eo ia
eaioini??ic aoea ae?aaiinoiaaia aacaeiaoyie/ia, o 68 (59,7 %) —
aeiaoyie/ia oi?ie oai?iae. Ca ao?ieia?/iith no?oeoo?ith 71,9 % noaiiaea
eaioini??ic, aeeeeeaiee L. icterohaemorrhagiae.

I?e oi?ioaaii? a?oi i?iaiaeeee aea??eiaee i?aea?? oeiieia?/ieo oai?eo ca
aeeeth/aiiyi iaoe??io?a ?c noiooiueith iaoieia??th na?oeaai-noaeeiii?
nenoaie. Aeae?eai? a?oie aoee ni?anoaaeai? ca a?eii ? ni?aa?aeiioaiiyi
oai?eo ?c na?aaeiueiaaaeeei oa aaaeeei ia?aa?aii eaioini??ico.

O 30 i?aeoe/ii caei?iaeo aeiii??a, ni?anoaaeaieo ca a?eii ? noaooth,
i?iaaaeaii eiio?ieuei? eaai?aoi?i? oa ?ino?oiaioaeuei? aeine?aeaeaiiy.

On? oai?? aoee ianoaaeai? aei e?eoaaiiy, a ia??iae? ?iciaeo oai?iae
(7-10 aeaiue), oa ia??iae? ?aeiiaaeanoeaioe?? (17-20 aeaiue).

Aeey aeinyaiaiiy iinoaaeaii? iaoe ? ?ica’ycaiiy caaea/ aea?aii
a?aeiia?aeiee eiiieaen ee?i?ei-eaai?aoi?ieo iaoiae?a aeine?aeaeaiiy:

— aea/aiiy o oai?eo ia eaioini??ic ee?i?/ieo iniaeeainoae noaio
na?oeaai-noaeeiii? nenoaie c ?a?no?aoe??th ?o ia ea?oao ianoaaeaiiy ?
ianooiiei ii??aiyiiyi /aiaiiac, ia’?eoeaia ianoaaeaiiy/;

— aecia/aiiy ??aiy ?ioieneeaoe?eiiai neiae?iio (ne?ei?iaiaee iaoiae
aecia/aiiy iaioeae?a na?aaeiueiiieaeoey?ii? iane (N.A. Aaeaeo?iiia,
1983), eaeeioeeoa?iee ?iaeaen ?ioieneeaoe?? (ca oi?ioeith
ss.ss.Eaeueo-Eae?oa), aaiaoieia?/iee iieaciee ?ioieneeaoe?? (ca A.N.
Aaneeue?aei, 1994);

— aeaeo?iea?ae?ia?ao?/i? ianoaaeaiiy i?iaiaeeee c aeiiiiiaith
oanoeeaiaeueiiai aeaeo?iea?ae?ia?aoa ”Aeei?” a iniiaieo ? aeiaeaoeiaeo
a?aeaaaeaiiyo;

— iieacieee oeaio?aeueii? aaiiaeeiai?ee ? nei?ioeeao ooieoe?th i?iea?aeo
aea/aee iaoiaeii aoiea?ae?ia?ao?? ca aeiiiiiaith aia?aoo “Niiineii-30”,
yeee i?aoethaaa a I-?aaeei?, ei?enooth/enue iieacieeaie cai?iiiiiaaieie
A.A.Ca?aoeueeei (1979);

— iieacieee ?aiaaiaoia?ai oa ?aiaacia?ai aea/aee ca aeiiiiiaith ?aia?aoa
?A-2-02 ?c caienii iieaciee?a ia oanoeeaiaeueiiio ea?ae?ia?ao? ca
iaoiaeeeith, cai?iiiiiaaiith O.Ae. Aeoeiaei (1986);

— aeine?aeaeaiiy noaio i?e?ioee?eoeyoe?? iaoiaeii eii’thieoeaaeueii?
a?ii?e?ineii?? aecia/aee ca A.N. Aieeiaei (1977);

— noai noaeeiii-o?iiaioeeoa?ii? ? eiaaoeyoe?eii? eaiie aaiinoaco aea/aee
ca iieacieeaie ?acenoaioiino? eai?ey??a (iaoiae
Eii/aeianueeiai-?oiiaey-Ea?aea, 1980).

E??i oiai aecia/aee:

— oaeoi? A?ee?a?aiaea ca Weiss a iiaeeo?eaoe?? I.A. Oeeaoeueiai? (1968);

— e?euee?noue o?iiaioeeo?a ca iaoiaeii ?. ?. Aeaiee?ia ? A.E.
E?eaeai?anueeiai (1967);

— aa?aaaoe?th o?iiaioeeo?a ca iaoiaeii Born a iiaeeo?eaoe?? A.I.
Aaeoaee (1968);

— aaeaaceai?noue o?iiaioeeo?a ca Salzman (1967);

— ai?no aioeo?iia?io ??? ca iaoiaeeeith Hensen, Loeliger a iiaeeo?eaoe??
E.I. Aeoaanueeiai (1978);

— noai nenoaie cn?aeaiiy e?ia? aiae?coaaee ca iieacieeaie eiaaoeia?ai;

— iaoiii?oieia?/i? aeine?aeaeaiiy aeeiiaii ca o?aaeeoe?eieie
iaoiaeeeaie.

Na?ieia?/ii oeo? aioeo?e a aeeiai?oe? caoai?thaaiiy aecia/aee ca
aeiiiiiaith ?aaeoe?? i?e?iaaethoeiaoe?? ia aac? eaai?aoi??? iniaeeai
iaaacia/ieo ?ioaeoe?e iaeanii? NAN.

Noaoenoe/io ia?iaeo io?eiaieo ?acoeueoaoia i?iaiaeeee ca aeiiiiiaith
iie?ieaeueeoeyoi?a «Aeaeo?iiiea IE-61» c aeei?enoaiiyi aiaeiiaiaeieo
i?ia?ai.

Oa?aeoa?enoeea ii?ooaiue na?oeaai-noaeeiii? nenoaie o oai?eo ia
eaioini??ic

A ?acoeueoao? aeine?aeaeaiiy aeyaeee, ui aaea a ii/aoeiaiio ia??iae?
caoai?thaaiiy o oai?eo ia eaioini??ic c na?aaeiueiaaaeeith oa aaaeeith
oi?iaie niinoa??aaeenue noa’?eoeai? ? ia’?eoeai? i?iyae o?aaeaiue
na?oeaai-noaeeiii? nenoaie (oaae. 1).

Oaaeeoey 1

Noa’?eoeai? ? ia’?eoeai? ee?i?/i? i?iyae ii?ooaiue na?oeaai-noaeeiii?
nenoaie a oai?eo ia eaioini??ic o ii/aoeiaiio ia??iae?

E?euee?noue oai?eo

Iciaee caoai?thaaiiy aacaeiaoyie/ia oi?ia, n=46 aeiaoyie/ia oi?ia, n=68

aan. % aan. %

Aie? a ae?eyioe? na?oey 15 32,6 31 48,5

A?ia?ai?y iaee//y 21 45,6 41 60,3

?i’?eoe?y noaeei neea? 24 52,2 60 88,2

E?iaiaeeeae a neea?o 18 39,1 33 48,5

Aaii?aa?/i? aeneiaiiy 16 34,8 31 45,6

I?aeaeuaia e?iaioi/ea?noue 12 26,1 23 33,8

?icoe?aiiy iaae na?oey 4 8,7 9 13,2

Nenoie?/iee ooi iaae aa?o?aeith na?oey 24 52,2 43 63,2

I?eaeooai?noue na?oeaaeo oii?a 33 71,7 62 91,2

A?aaeeea?ae?y 11 23,9 17 25,0

Oao?ea?ae?y 18 39,1 42 61,8

A?eoi?y 9 19,6 16 23,5

A?oa??aeueia a?iioii?y 39 84,8 61 89,7

O aeiaaeeo ?aiiuei? aini?oae?caoe?? /anoioa aeyaeaieo ci?i
na?oeaai-noaeeiii? nenoaie noaiiaeea 19,1 %. I?e aini?oae?caoe??
i?ney 6-8 aeiy caoai?thaaiiy niinoa??aaeinue ca?eueoaiiy e?eueeino?
o?aaeaiue na?oeaai-noaeeiii? nenoaie aei 54,5-75,0 %. .

Ia?inoaiiy ?ioieneeaoe?eiiai neiae?iio noi?iaiaeaeoaaeinue ?inoii
noa’?eoeaieo ? ia’?eoeaieo ci?i c aieo na?oeaai-noaeeiii? nenoaie o
oai?eo ia eaioini??ic. Iaea?eueo /anoi o?aaeaiiy niinoa??aaeenue o
oai?eo c III nooiaiai ?ioieneeaoe?eiiai neiae?iio (68,2 %).

Ii?ooaiiy i?iea?aeo, eiai noaeeiiiai ?onea iathoue oaciee oa?aeoa?.
A?ae eae?a?o cao?iiaiaaieo noaeei ? nooiaiy ieethc?? caeaaeeoue
iioe?ai?noue ? aeeaeia aaiiaeeiai?/ieo ? aeano?oeoeaieo ii?ooaiue a
noaeeiao, i?aaiao ? oeaieiao (I.A.I?eia/aiei ? ni?aaao., 1986).

I?e a?io?i?/iiio aeine?aeaeaii? aeyaeee aeinoia??ia i?aeaeuaiiy
aeoeaiino? oa?iaioo AnAO, ui oaeiae na?ae/eei i?i aoyaiaiiy a
iaoieia?/iee i?ioean na?oeaaiai i’yca (p<0,05). O oai?eo iaio a?oi aeyaeee aeinoia??ia i?aeaeuaiiy a ne?iaaooe? e?ia? ??aiy e?aaoei?io oa na/iaeie, ui na?ae/eei i?i o?aaeaiiy ?aiaeueii? nenoaie. Oae, o oai?eo c aacaeiaoyie/iith oi?iith eaioini??ico ??aaiue e?aaoei?io aeinyaaa 242±14 ieiieue/e, na/iaeie - 10,9±1,5 iiieue/e, o oai?eo c aeiaoyie/iith oi?iith - 290±16 ieiieue/e ? 12,4±1,7 iiieue/e a?aeiia?aeii. O?aaeaiiy i?iyaeyeeny iayai?noth a na/? a?eea, cia/iith e?euee?noth eaeeioeeo?a, a?eo?ioeeo?a, oeee?iae??a, ?icaeoeii ie?ao???, aio???. I?e aeaeo?iea?ae?ia?ao?/iiio ianoaaeaii? o oai?eo ia eaioini??ic aeyaeee ci?ie, ye? i?iyaeyeeny, a iniiaiiio, ci?iaie coaoey O ? naaiaioa SO, ii?ooaiiyi ooieoe?e aaoiiaoecio i?iea?aeo, a?eoi?yie, ii?ooaiiyi i?ia?aeiino?. Aeyaeai? ci?ie i?aaenoaaeai? o?ueiia neiae?iiaie: a?eoi?/iei, ii?ooaiiyi i?ia?aeiino? ? ?ioieneeaoe?eii-aeeno?io?/iei. O oai?eo ia eaioini??ic iae/ano?oa niinoa??aaany ?ioieneeaoe?eii-aeeno?io?/iee neiae?ii (37,6 %). Iieacieee oeaio?aeueii? aaiiaeeiai?ee o oai?eo ia eaioini??ic aeaee iiaeeea?noue aecia/eoe ?ieue ? aeeaeio aaiiaeeiai?/ieo ii?ooaiue a caeaaeiino? a?ae oi?ie eaioini??ico. Aoei aeae?eaii o?e oeie aaiiaeeiai?ee: ii?iiaeeiai?/iee, a?ia?aeeiai?/iee ? a?iiaeeiai?/iee. O oai?eo ia eaioini??ic c aacaeiaoyie/iith ? aeiaoyie/iith oi?iaie ia?aaaaeaa a?ia?aeeiai?/iee oei e?iaiia?ao, yeee oa?aeoa?ecoaaany ca?eueoaiiyi /anoioe na?oeaaeo nei?i/aiue, oaea?iiai oa nenoie?/iiai ?iaeaen?a oa cieaeaiiyi caaaeueiiai ia?eoa?e/iiai iii?o noaeei. Ii?ooaiiy i?e?ioee?eoeyoe?? aeyaeai? ye ia ??ai? ae??aieo noaeei, oae ? ia aioo??oiueii?aaiiiio ??ai?. I?ia?anoaaiiy caoai?thaaiiy i?ecaiaeeei aei ?icaeoeo ii?oieia?/ieo ci?i o aeaeyae? ciaioaiiy eai?ey?ecaoe?? oeaiei, iaiiaiioe?iiino? ooieoe?iioth/eo eai?ey??a (aeaoi?iaoe?y, caeaeno?noue, ooai?aiiy aiaa?eci). Oe? yaeua ii?aeioaaeenue c ae?aaeaiith iaoieia??th eai?ey?ii? i?iieeeeaino?, neaaeae-oaiiiaiii, niia?eueiaiiyi i?noeaaiai e?iaiia?ao. Ie?ai? aaoi?e (A.N.Nieie, A.O.E?naeueiaa, 1992) aeacothoue, ui o oai?eo iiaea iaoe i?noea aaii?aa?/iee neiae?ii, yeee ? iieacieeii aaaeeino? caoai?thaaiiy, a ia??aeei ? ia?aaea?nieeii aeieeiaiiy oneeaaeiaiue. Io?eiai? iaie aeai? i?aeoaa?aeaeothoue ? ?icaeaathoue oe? iieiaeaiiy. Cieaeaiiy ?acenoaioiino? eai?ey??a aoei cao?eniaaii o 14 (30,4 %) oai?eo c aacaeiaoyie/iith ? o 32 (47,1 %) oai?eo c aeiaoyie/iith oi?iaie eaioini??ico. Ae?aaeai?noue aaii?aa?/iiai neiae?iio ciaoiaeeeanue o i?yi?e caeaaeiino? a?ae aeeaeie o?aaeaiiy noaeeiii? no?iee. I?i nooi?iue o?aaeaiino? noaeeiii? no?iee na?ae/eoue ??aaiue o e?ia? oaeoi?a A?ee?a?aiaea - a?eea, yeee neioaco?oueny a aiaeioae?? noaeei ? ca?eueiy?oueny i?e iioeiaeaeaii? aaeoa??aeueieie aaaioaie, oieneiaie, ?ioiieie eiiieaenaie (A.I.Ae?iaeoaaa ? ni?aaao., 1995). Aea/aiiy iieacaei, ui eiai eiioeaio?aoe?y cia/ii ca?eueoaia aaea a ii/aoeiaiio ia??iae? eaioini??ico, neeaaeath/e o oai?eo c aacaeiaoyie/iith oi?iith - 226,7±12,7 % (?<0,001) oa 274,4±14,9 %, (?<0,001) o oai?eo c aeiaoyie/iith oi?iith. I?aeaeuaiiy eiioeaio?aoe?? oaeoi?a A?ee?a?aiaea a iiaeaeueoiio ei?aethaaei c aaaee?noth caoai?thaaiiy oa ?ioaineai?noth aaii?aa?/iiai neiae?iio. A.Davenport ? ni?aaao. (1989) oa ?io? iaoeiaoe? i?aee?aneththoue aaaeeea?noue aea/aiiy aioo??oiueinoaeeiiiai cn?aeaiiy ? aa?aaaoe?? o?iiaioeeo?a, aaaaeath/e, ui oe? i?ioeane aaciina?aaeiuei caeiathoue iaeia c i?ia?aeieo iieiaeaiue a iaoiaaiac? eaioini??ico, aieeaathoue ia ia?aa?a ? iane?aeie caoai?thaaiiy. I?e aeine?aeaeaii? o?iiaioeeoa?ii? eaiee aaiinoaco o oai?eo c aacaeiaoyie/iith ? aeiaoyie/iith oi?iaie eaioini??ico e?euee?noue o?iiaioeeo?a aoea aeinoia??ii ciaioaiith (p<0,001). ?iaeea?aeoaeuei? eieeaaiiy e?eueeino? o?iiaioeeo?a aoee a iaaeao 105-260 A/e. O oai?eo ia eaioini??ic niinoa??aaeanue ia o?eueee o?iiaioeeoiiai?y, aea ? aeoeaaoe?y aa?aaaoe?? oa aaeaac?? o?iiaioeeo?a. I?e aeine?aeaeaii? eiaaoeyoe?eii? eaiee aaiinoaco o 32,9 % oai?eo aeyaeaii a?iieiaaoeyoe?th. I?e aea/aii? iaoiii?oieia?/ieo ci?i i?e eaioini??ic? niinoa??aaee iiaiie??a'y i?aai?a ? cia/i? iae?ia?ioe/i? ci?ie, e?iaiaeeeae, noac, aiaieuaaee iae?ia?ic ? iae?ic, o?a?eiia? o?iiaice, ye? ia?aaaaeii aoee ae?aaeai? a ie?eao, ia/?ioe?, i?iea?ae?. Aeey eaoaeueieo aeiaaee?a oa?aeoa?i? /enaeuei? e?iaiaeeeae iaeaea o an? i?aaie. Cia/i? ?iceaaee i?e?ioee?eoeyoi?iiai ?onea ni?e/eiyee eiai aeieaaeo, aeeeeeath/e iacai?ioi? ci?ie a i?aai?ci? oai?iai. I?e a?noieia?/iiio aeine?aeaeaii? a i?iea?ae? aeyaeyee iiaiie??a'y, ?ioa?noeoe?aeueio ?io?eueo?aoe?th, a?eeiao aeeno?io?th, aiaieuaa? iioeiaeaeaiiy ea?ae?ii?ioeeo?a, ae?aaeaiee iaa?ye ?ioa?noeoe?th ? aenoaeaoeaii-i?iaeoeoeaiee aiaieuaaee i?iea?aeeo. Ia iaoo aeoieo, o ca'yceo c oienai??th ?icaeaa?oueny aaia?ae?ciaaiee eai?ey?ioieneeic, yeee aaaea aei ii?ooaiue a nenoai? aaiinoaco, i?e?ioee?eoeyoi?ieo ?iceaae?a ? a?iien??, ye? a iiaeaeueoiio iaaaoeaii aieeaathoue ia noai na?oeaai-noaeeiii? nenoaie. Aeey onoiaiiy aeyaeaieo ci?i a na?oeaai-noaeeii?e nenoai?, nenoai? aaiinoaco oa i?e?ioee?eoeyoe?? o oai?eo ia eaioini??ic iaie ?ic?iaeaiee iaoiae e?eoaaiiy c canoinoaaiiyi aoaiceeaoo iao??th oa ?eaieneio a eiia?iaoe?? c eiiieaeniith oa?ai??th. I?e ee?i?/iiio aeine?aeaeaii? aecia/aii iioeiaeueia ii?aeiaiiy eiiieaenii? oa?ai?? c aoaiceeaoii iao??th oa ?eaieneiii. An?o ianoaaeaieo oai?eo, a caeaaeiino? a?ae canoiniaaieo oa?aiaaoe/ieo iaoiaeee ? oi?i eaioini??ico, aoei iiae?eaii ia 6 a?oi. Eiaeia a?oia iiaeieyeanue ia aeai iiaea?oie a caeaaeiinoi aiae iayaiinoi aeiaoyieoei: I - aacaeiaoyie/ia, II - aeiaoyie/ia. Oai?i a?oi A io?eioaaee eiiieaenio oa?ai?th, oai?i a?oi A io?eioaaee ia oiii eiiieaeniiai eieoaaiiy ?eaienei, oai?i a?oi A - ?eaienei ? aoaiceeao iao?ith. Aoaeoeai?noue cai?iiiiiaaiiai eiiieaeniiai e?eoaaiiy oai?eo ia eaioini??ic I?e aiae?c? ?acoeueoao?a e?eoaaiiy 6 a?oi oai?eo ia eaioini??ic aeyaeaii, ui i?ecia/aiiy aei eiiieaeniiai e?eoaaiiy aoaiceeaoo iao??th oa ?eaieneio ia? i/aaeaei? ia?aaaae ii??aiyii ?c caaaeueiii?eeiyoei e?eoaaiiyi aai ?c canoinoaaiiyi o?eueee ?eaieneio. Oea ni?eyei aeinoia??iiio ciaioaiith o?eaaeino? iniiaieo noa'?eoeaieo ee?i?/ieo i?iya?a o oai?eo ?-A oa ??-A ee?i?/ieo a?oi (caaaeueia neaa?noue, aieiaiee a?eue, i?aea??, aie? a ae?eyioe? na?oey). Aiaeia?/ii ciaioeeanue o?eaae?noue ia'?eoeaieo ee?i?/ieo i?iya?a (i?eaeooai?noue na?oeaaeo oii?a, nenoie?/iee ooi, a?aaeeea?ae?y, oao?ea?ae?y, a?eoi?y, a?oa??aeueia a?iioii?y), p<0,001. O oai?eo iniiaieo ee?i?/ieo a?oi (?-A ? ??-A) ia 5-oo aeiao a?ae ii/aoeo e?eoaaiiy aoee a?aenooi? na?ae? i?ney?i'?eoe?ei? e?iaiaeeeae, aaii?aa?/i? aeneiaiiy, e?iaiaeeeae a neea?o, i?eieieeenue e?iaioa/? c iina ? ynai. Eiiieaenia oa?ai?y ?c i?ecia/aiiyi ?eaieneio oa aoaiceeaoo iao??th ni?eyea aeinoia??iiio ciaioaiith i?iya?a ?ioieneeaoe?eiiai neiae?iio, ui cieaeoaaei /enei aaaeeeo oi?i eaioini??ico. Iiceoeaiee aieea cai?iiiiiaaiiai e?eoaaiiy i?iyaeyany ?c cieaeaiiyi aeoeaiino? i?iea?ae?aeueiiai oa?iaioo - AnAO, oiae? ye o oai?eo ?ioeo a?oi (?-A, ??-A, ?-A, ??-A) eiai cieaeaiiy aoei iaaeinoia??iei (?>0,05).

A?aei?/aii nooo?aee aieea cai?iiiiiaaiiai e?eoaaiiy ia ooieoe?th
?aiaeueii? nenoaie. Oae, o oai?eo ?-A ee?i?/ii? a?oie ??aaiue e?aaoei?io
a ne?iaaooe? e?ia? cieceany aei 115±8 ieiieue/e (p<0,001), ??-A - 128±9 ieiieue/e (p<0,001), aeinoia??ii a?ae??ciyth/enue a?ae iieaciee?a A ? A a?oi. A ?acoeueoao? i?iaaaeaiiai e?eoaaiiy ciaioeeanue ae?aaeai?noue ii?ooaiue ooieoe?? aaoiiaoecio, i?ioean?a ?aiiey?ecaoe?? na?oeaaiai i'yca. O 4 (22,2 %) oai?eo ?-A ? o 8 (30,8 %) oai?eo ??-A ee?i?/ieo a?oi a?aei?/aii iiceoeaio aeeiai?eo ?ioa?aaeo SO, a?aeiia?aeii o 5 (27,8 %) ? o 13 (50,0 %) oai?eo iaea i?noea ii?iae?caoe?y coaoey O. *anoioa ?ioeo aeaeo?iea?ae?ia?ao?/ieo ii?ooaiue oaeiae iaea oaiaeaioe?th aei ciaioaiiy (oaae. 2). Oaaeeoey 2 *anoioa aeaeo?iea?ae?ia?ao?/ieo ci?i o oai?eo ia eaioini??ic a ia??iae? ?aeiiaaeanoeaioe?? i?ae aieeaii eiiieaeniiai ? cai?iiiiiaaiiai e?eoaaiiy, % Aeaeo?iea?ae?ia?ao?/i? Ee?i?/i? a?oie ii?ooaiiy ?-A n=14 ?-A n=14 ?-A n=18 ??-A n=20 ??-A n=22 ??-A n=26 1 2 3 4 5 6 7 Ci?uaiiy ?ioa?aaeo ST a?ae ?cie?i?? a?eueoa 1 ii 21.4 14.3 5.6 25.0 18.2 11.5 Ci?ie coaoey O: a?iiene/i? 14.3 14.3 5.6 25.0 13.6 7.7 ?oai?/i? 7.1 - - 5.0 4.5 - 1 2 3 4 5 6 7 Iieaciee TV1>TV6 — — — 10.0 9.1 3.8

Neioniaa a?eoi?y 21.4 14.3 11.1 25.0 18.2 11.5

Neioniaa oao?ea?ae?y 7.1 7.1 — 15.0 9.1 3.8

Neioniaa a?aaeeea?ae?y 14.2 7.1 — 15.0 9.1 7.7

Aeno?anenoie?y:

noi?aaaio?eeoey?ia 7.1 — — 10.0 9.1 3.8

oeoii/eiaa — — — 5.0 4.5 —

Aeieaaee:

aioo??oiueiia?aaena?aeia — — — 5.0 4.5 3.8

ao??iaaio?eeoey?ia 7.1 — — — — —

i?aeie io/ea A?na 7.1 7.1 — 10.0 9.1 3.8

Aiae?c iieaciee?a oeaio?aeueii? aaiiaeeiai?ee iieacaa, ui o oai?eo ia
eaioini??ic c a?ia?aeeiai?/iei oeiii e?iaiia?ao iieacieee ci?ithaaeenue
o cai?ioiueiio iai?yieo a cia/ii ei?ioo? oa?i?ie. Oae, /a?ac 7-10
aei?a e?eoaaiiy oaea?iee ? nenoie?/iee ?iaeaene eieeaaeenue a iaaeao
49,26-51,42 ie/i2 oa 3,19-3,33 e/oa./i2 a?aeiia?aeii (p<0,01), /anoioa na?oeaaeo nei?i/aiue ciaiooaaeanue aei 86,1-90,6 oae./oa. (p<0,05), e?ioeaaee ae?anoie?/iee ia'?i oaeiae aeinoia??ii ciaiooaaany (p<0,05) o oai?eo 1-A oa 11-A ee?i?/ieo a?oi. A oie aea /an, o oai?eo ia eaioini??ic A ? A ee?i?/ieo a?oi oaei? oaiaeaioe?? aei c?inoaiiy iieaciee?a ia aoei. Ii?aeiaia canoinoaaiiy eiiieaenii? oa?aii? c aoaiceeaoii iao?ith i ?eaieneiii ciaiooaaei i?iieeeeainoue noaeeiii? noiiee i i?ecaiaeeei aei iiaiiai aiaeiiaeaiiy ?? ooieoeiiioaaiiy a cia/ii ei?ioo? oa?i?ie o ii??aiyii? c oai?eie ee?i?/ieo a?oi A ? A. Ciaioaiiy eiioeaio?aoe?? oaeoi?o Aiee?a?aiaea ia 18,6 ±2,1 % (p<0,05) o oai?eo ?-A ? ia 26,3±2,4% (p<0,05) o oai?eo ??-A ee?i?/ieo a?oi i?ney 7-10-ai aeiy e?eoaaiiy i?aeoaa?aeeei iiceoeaiee aoaeo cai?iiiiiaaiiai e?eoaaiiy, aeinoia??ii a?ae??ciyth/enue a?ae iieaciee?a oai?eo ?ioeo ee?i?/ieo a?oi. Iniaeeai aoaeoeaiei aeyaeany aieea i?iaaaeaiiai e?eoaaiiy o oai?eo ? A oa ?? A ee?i?/ieo a?oi ia noai o?iiaioeeoa?ii? eaiee aaiinoaco (?en. 1). I?aeaeuaiiy e?eueeino? o?iiaioeeo?a aeyaeee a e?ioe? ia?oiai oeaeiy o oai?eo ? A oa ?? A a?oi (p<0,001). A aiaeia?/i? oa?i?ie o oai?eo ?ioeo a?oi o?iiaioeeoiiai?y ia?inoaea. Cao?enoaaee oaeiae ae?aaeaiee ii?iae?coth/ee aoaeo aeeiai?/ii? aeoeaiino? o?iiaioeeo?a, oiaoi i?e canoinoaaii? eiiieaenii? oa?ai?? a eiia?iaoe?? c aoaiceeaoii iao??th oa ?eaieneiii aeinyaaee iiceoeaii? aeeiai?ee ?aieia?/ieo aeanoeainoae e?ia?. E?eoaaiiy oai?eo ia eaioini??ic ca cai?iiiiiaaiith iaoiaeeeith i?eaiaeeei aei ii?iae?caoe?? iieaciee?a eiaaoeyoe?eii? eaiee aaiinoaco a 44 oai?eo (p<0,01) a ii/aoeiaiio ia??iae? ?aeiiaaeanoeaioe??. I?ae aieeaii cai?iiiiiaaiiai e?eoaaiiy a?aei?oeee iiceoeai? ci?ie eii'thieoeaaeueii? i?e?ioee?eoeyoe??, cie?aia ciaioaiiy aioo??oiueinoaeeiieo ? ia?eaaneoey?ieo o?aaeaiue. I?ney 10-ai aeiy e?eoaaiiy ?iaeaen noaeeiieo ci?i ciaiooaaany ia 10,6±0,8 % o oai?eo ?-A oa 10,9±0,9 % o oai?eo ??-A ee?i?/ieo a?oi (p<0,05) o ii??aiyii? c iieacieeaie oai?eo a?oi A. ?iaeaen aioo??oiueinoaeeiieo ci?i ciaiooaaany a?aeiia?aeii ia 21,0±1,7 %, 20,8±1,4 % (?<0,05), caaaeueiieii'thieoeaaeueiee ?iaeaen cieaeoaaany ia 16,2±1,2 % oa 16,6 ±1,1 % (?<0,05). Ii?aeiaia aeei?enoaiiy aoaiceeaoo iao??th ? ?eaieneio ?acii c o?aaeeoe?eiith oa?ai??th cia/ii iie?ioeei noai aioo??oiueiia/?ieiaiai e?iaiia?ao. Oae, ?aia?ao?/iee ?iaeaen c?inoaa ia 11,1±0,8 % (?<0,05), oiion ? aeanoe/i?noue noaeei ii?iae?coaaeenue o 94,3% oai?eo. Iiceoeaiei aeyaeany aieea cai?iiiiiaaiiai e?eoaaiiy ia oae? iieacieee, ye /an e?iaiiaiiaiaiiy, aaee/eio oaea?iiai ia'?io e?ia?, oaeaee?noue iaiiaiaiiy a?oa??ie a i?aai?. Iiceoeaio aeeiai?eo niinoa??aaee ? noiniaii iieaciee?a aaiiciiai ?onea ia/?iee: ca?eueooaaeinue ioeueniaa e?iaiiaiiaiaiiy, ciaiooaaany ia?eoa?e/iee ii??, oiaoi cai?iiiiiaaiee iaoiae e?eoaaiiy i?eaiaeea aei ii?iae?caoe?? e?iaiia?ao a ia/?ioe?. ?ic?iaeaiee iaoiae e?eoaaiiy iaeni?eyoeea?oa aieeioa ia noai noaeeiii-o?iiaioeeoa?iiai aaiinoaco. Ciaioaiiy i?iieeeeaino? noaeeiii? no?iee, cieaeaiiy oaeoi?a A?ee?a?aiaea iiaeia aaaaeaoe ia'?eoeaieie e?eoa??yie iiia?aaeaeaiiy ?icaeoeo aeenai?iiaaiiai aioo??oiueinoaeeiiiai cn?aeaiiy e?ia?. Ii?iae?caoe?y e?eueeino? o?iiaioeeo?a, ?o ooieoe?iiaeueii? aeoeaiino? caiia?aaea ?icaeoeo ii?ooaiue i?e?ioee?eoeyoe??, iiceoeaii aieeaath/e ia iieacieee oeaio?aeueii? oa ia?eoa?e/ii? aaiiaeeiai?ee, nei?ioeeao ooieoe?th i?iea?aeo. Ioaea, ii?aeiaia aeei?enoaiiy eiiieaenii? oa?ai??, aoaiceeaoo iao??th oa ?eaieneio iiceoeaii aieeaaei ia ia?aa?a eaioini??ico, ui iiia?aaeaeoaaei ?icaeoie oneeaaeiaiue ? ni?eyei onoiaiith ii?ooaiue a i?aaiao ? nenoaiao, ye? aeieeaee i?ae aieeaii eaioini??icii? ?ioaeoe??. Oaeei /eiii, ?ic?iaeaia iaoiaeeea e?eoaaiiy oai?eo ia eaioini??ic ?aeiiaiaeo?oueny aeey aeei?enoaiiy a ee?i?oe? ?ioaeoe?eieo oai?ia ye can?a oa?ai?? ? i?io?eaeoeee aaii?aa?/iiai neiae?iio, i?e?ioee?eoeyoi?ieo ii?ooaiue oa ?iceaae?a na?oeaai-noaeeiii? nenoaie. AENIIAEE 1. A ee?i?/i?e ea?oei? ??cieo oi?i eaioini??ico iathoue i?noea i?iyae o?aaeaiue na?oeaaiai i'yca, ye? iieyaathoue o aeieeiaii? a?eoi?e, ii?ooaiue i?ia?aeiino? oa ?ioieneeaoe?eii-aeeno?io?/ieo o?aaeaiue. Ii?oieia?/ii o?aaeaiiy i?iea?aea ?aeaioeo?eothoueny ye aiaieuaaee i?iea?aeeo, aai caiaeueii-?ioieneeaoe?eia aeeno?io?y ea?ae?ii?ioeeo?a. Eaioini??iciee i?iea?aeeo i?iyaey?oueny ?icoe?aiiyi iaae na?oey, a?eoi?yie, ii?ooaiiyie i?ia?aeiino?, ania?oaoai?iio?ainoa?acai??th. I?i aeeno?io?th i?iea?aea o oai?eo ia eaioini??ic na?ae/aoue ?cieueiaai? ci?ie ?aiiey?ecaoe?eiiai naaiaioa, aeaeo?iea?ae?ia?ao?/i? ii?ooaiiy aaoiiaoecio. 2. I?e eaioini??ic? /anoi aeieeathoue ii?ooaiiy oeaio?aeueii? aaiiaeeiai?ee, ye? iathoue ??ciini?yiiaaiee oa?aeoa? ? i?iyaeythoueny ii?ooaiiyie /anoioe na?oeaaeo nei?i/aiue, oaea?iiai oa na?oeaaiai ?iaeaen?a, oaeeeiiiai ia'?io na?oey, caaaeueiiai ia?eoa?e/iiai iii?o noaeei. 3. Eaioini??ic ni?e/eiy? ii?ooaiiy i?e?ioee?eoeyoe??, ye? iieyaathoue o aeieeiaii? iiaiie??a'y, ia?eaaneoey?iiai iaa?yeo, niaaeo aaioe ? eai?ey??a, ciaioaii? ?o e?eueeino?, aeieeiaii? i?e?iaiaa?eci, i?aeaeuaii? eii'thieoeaaeueieo ?iaeaen?a. 4. A iaoiaaiac? eaioini??ico cia/io ?ieue a?ae?a?athoue ci?ie aaiinoaco, iniaeeai a noaeeii?e ? o?iiaioeeoa?i?e eiai eaieao, ui oa?aeoa?ecothoueny i?aeaeuaiith i?iieeeea?noth ? eaie?noth noaeeiii? no?iee, ca?eueoaiiyi ai?noo oaeoi?a A?ee?a?aiaea, ae?aaeaiith o?iiaioeeoiiai??th, ii?ooaiiyi aa?aaaoe?eii? ? aaeaaceaii? ooieoe?e o?iiaioeeo?a. 5. Ii?aeiaia aeeth/aiiy aei eiiieaenii? oa?ai?? oai?eo ia eaioini??ic ?eaieneio ? aoaiceeaoo iao??th aeicaiey? i?enei?eoe cai?ioi?e ?icaeoie iaoieia?/ieo i?iya?a o?aaeaiiy i?iea?aea, ciaiooaaoe ? aoaeoeaii e?ea?aeiaoaaoe i?iyae ii?ooaiue aaiinoaco ? i?e?ioee?eoeyoe?? (noaa?e?caoe?y noaeeiii? no?iee, cieaeaiiy ai?noo oaeoi?o A?ee?a?aiaea, ca?eueoaiiy e?eueeino? o?iiaioeeo?a ? ii?iae?caoe?y ?o ooieoe?iiaeueii? aeoeaiino?, ciaioaiiy ?ioieneeaoe?eiiai neiae?iio). Cai?iiiiiaaia e?eoaaiiy a ?aii? no?iee eaioini??ico iiia?aaeaeo? aeieeiaiiy ea?ae?aeueiiai neiae?iio ? ii?ooaiiy i?e?ioee?eoeyoe?? a ia??iae? ?iciaeo oai?iae. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Ith?ee A.O., Aeeeee A.I., Aeooei E.A. I?iyae aaii?aa?/iiai neiae?iio i?e eaioini??ic? // Aaeeoeueeee e?ea?nueeee a?niee. - 1997. - O. 4, ? 1. - N. 56-58. 2. Ith?ee A.O., Aeeeee A.I., Aeooei E.A., Cae?ae I.I. Iaoiii?oieia?y ?eoa?iaaii?aa?/iiai eaioini??ico a ?aaii-O?aie?anuee?e iaeano? // Aaeeoeueeee e?ea?nueeee a?niee. - 1997. - O. 4, ? 2. - N. 90. 3. Ith?ee A.O. O?aaeaiiy na?oeaai-noaeeiii? nenoaie i?e ?eoa?iaaii?aa?/iiio eaioini??ic? // Aaeeoeueeee e?ea?nueeee a?niee. - 1998. - O. 5, ? 1. - N. 66-67. 4. Ith?ee A.O., Aeeeee A.I., Aeooei E.A. Noai o?iiaioeeoa?ii-noaeeiiiai aaiinoaco oai?eo ia eaioini??ic// ?ioaeoe?ei? oai?iae.- 1998.- ?4.-N.44-46. 5. Ith?ee A.O. O?aaeaiiy na?oeaai-noaeeiii? nenoaie i?e eaioini??ic? // 18 iaeania iaoeiaa eiioa?aioe?y iieiaeeo a/aieo-iaaeee?a: Oace aeii. - ?aaii-O?aie?anuee, 1994. - N. 29. 6. Ith?ee A.O. ?iciianthaeaeai?noue eaioini??ico ia I?eea?iaoo?: I?aeia?iaeiee Eiia?an Iieiaeeo A/aieo Oe?a?ioe?a: Oac. aeii. - ?aaii-O?aie?anuee, 1994. - N. 99. 7. Aeeeee A.I., I?e?oi?iaa O.I., Aaneeee E.A., Canooa A.I., I?eoeye I.ss., Ith?ee A.O. Aioa?ini?aoe?y a e?eoaaii? oai?eo ia eaioini??ic: Ca. iaoeiaeo ?ia?o eiio. aei 100-??//y EIAe?A?O. - Ee?a, 1996. - N. 86. 8. Canooa A.I., I?e?oi?iaa O.I., Ith?ee A.O. Ae?aaiinoeea eaioini??ico ia aeiaini?oaeueiiio aoai? // Ca??iee "Caei?ia'y oa a?aeoai?aiiy ianaeaiiy ia I?eea?iaoo?". - ?aaii-O?aie?anuee, 1993. - N. 72. 9. Ith?ee A.O., Aeeeee A.I., Aeooei E.A. Aoaeoeai?noue canoinoaaiiy aoaiceeaoo iao??th aeey iiia?aaeaeaiiy aaii?aa?eiiai neiae?iio i?e eaioini??ic? // Iaoe. i?aeo. eiio. "No/ani? aniaeoe iaa?aeeeaaeii? iaaee/ii? aeiiiiiae": Oac. aeii. - Euea?a, 1997. - N. 113. 10. Ith?ee A.O. Aeeiai?ea iieaciee?a ooieoe?iiaeueiiai noaio ia/?iee o oai?eo ia eaioini??ic i?e e?eoaaii? ?eaieneiii // Ca. iaoeiaeo ?ia?o, aei. 5. - Euea?a, 1997. - N. 32. 11. Ieeeoi?iaa O.I., Aeeeee A.I., Coaee O.I., Canooa A.I., Aaneeee E.A., I?eoeye A.ss. ,Ith?ee A.O. Yioa?ini?aoeey a ea/aiee ae?oniuo aaiaoeoia, eaioinie?icia e ino?uo eeoa/iuo eioaeoeee // Eiioa?aioeey e 100-eaoeth eioaeoeeiiiie eaoaae?u ?innee "Eioaeoieiaey. Aeinoeaeaiey e ia?niaeoeau": Oac. aeiee. - Naieo-Iaoa?ao?a, 1996. - N. 72-73. 12. Ith?ee A.O., Inoye ?.N., I?e?oi?iaa O.I. Ai?aeai?ieia?/ia oa?aeoa?enoeea eaioini??ic?a a ?aaii-O?aie?anuee?e iaeano? // Iaoe. i?aeo. eiio. ? ieaioi Anioe?aoe?? ?ioaeoe?ii?no?a Oe?a?ie: Oac. aeii. - Ioea/aai, 1998. - N. 115-116. 13. Ith?ee A.O., Aeooei E.A. Noai i?e?ioee?eoeyoe?? oa i?iieeiino? noaeeiii? no?iee o oai?eo ia eaioini??ic // Y c'?cae ?ioaeoe?ii?no?a Oe?a?ie. - Oa?iii?eue, 1998. - N. 179-180. 14. Ith?ee A.O., Aeeeee A.I. Niin?a e?eoaaiiy oai?eo ia eaioini??ic c canoinoaaiiyi aoaiceeaoo iao??th ? ?eaieneio // ?aoe?iiae?caoi?nueea i?iiiceoe?y. Iina?ae/aiiy ? 37/2326 a?ae 30.06.97 ?. ?aaii-O?aie?anueea iaaee/ia aeaaeai?y. AIIOAOe?ss Ith?ee A.O. Na?oeaai-noaeeii? ?iceaaee o oai?eo ia eaioini??ic ? iaoiaee ?o ei?aeoe??. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.13. - ?ioaeoe?ei? oai?iae. - Iaoeiai-aeine?aeiee ?inoeooo ai?aeai?ieia?? oa ?ioaeoe?eieo oai?ia ?i. E.A. A?iiaoaanueeiai, Ee?a, 1999. Anoaiiaeaii, ui i?e eaioini??ic? ?icaeaathoueny o?aaeaiiy noaeeiii- o?iiaioeeoa?ii? oa eiaaoeyoe?eii? eaiie aaiinoaco, ye? aaaeooue aei ii?ooaiue i?e?ioee?eoeyoe?? ye ia ??ai? ae??aieo noaeei, oae ? ia aioo??oiueii?aaiiiio ??ai?, a oaeiae aei iia??oaiiy iieaciee?a oeaio?aeueii? aaiiaeeiai?ee, ?icaeaeoeo a?iien?? oeaiei. O?aaeaiiy na?oeaai-noaeeiii? nenoaie oa?aeoa?ecothoueny ?icaeoeii oaeeo neiae?ii?a, ye ?ioieneeaoe?eii-aeeno?io?/iiai, ii?ooaiiy i?ia?aeiino? oa a?eoi?/iiai. C iaoith aecia/aiiy iioeiaeueiiai ii?aeiaiiy eiiieaenii? oa?ai?? c aoaiceeaoii iao??th oa ?eaieneiii o oai?eo ia eaioini??ic aoee i?iaaaeai? ee?i?ei-eaai?aoi?i? oa ?ino?oiaioaeuei? aeine?aeaeaiiy. Anoaiiaeaii, ui ii?aeiaia aeei?enoaiiy aoaiceeaoo iao??th oa ?eaieneio, ye /anoeie ?ioaineaii? oa?ai?? aea? iiaeeea?noue iiia?aaeeoe aai ciaioeoe i?iyae aaii?aa?/iiai neiae?iio, ?icaeoie i?e?ioee?eoeyoi?ieo ii?ooaiue, o?aaeaiue na?oeaai-noaeeiii? nenoaie, a i?e ?o iayaiino? aeinyaoe oaeaeoiai iiceoeaiiai ee?i?/iiai aoaeoo. Eeth/ia? neiaa: eaioini??ic, aaiinoac, i?e?ioee?eoeyoe?y, i?iea?ae, e?eoaaiiy, aoaiceeao iao??th, ?eaienei. AIIIOAOeEss Ith?ee A.O. Na?aea/ii-ninoaeenoua ia?ooaiey o aieueiuo eaioinie?icii e iaoiaeu eo ei??aeoeee.-?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.13. - Eioaeoeeiiiua aieacie. - iao/ii-enneaaeiaaoaeueneee einoeooo yieaeaieieiaee e eioaeoeeiiiuo aieaciae ei. E.A.A?iiaoaaneiai, Eeaa, 1999. ?aaioa aace?oaony ia eeeieei-eaai?aoi?iii iaaethaeaiee, enneaaeiaaiee e ea/aiee 114 aieueiuo eaioinie?icii n?aaeiaoyaeaeie e oyaeaeie oi?iaie. Iieo/aiiua ?acoeueoaou eaai?aoi?iuo enneaaeiaaiee n?aaieaaee n iieacaoaeyie 30 i?aeoe/anee caei?iauo eeoe (aeiii?ia). Enneaaeiaaiea aeeth/aei eco/aiea o?iaiy eioieneeaoeeiiiiai neiae?iia, iieacaoaeae ninoaeenoiai, o?iiaioeeoa?iiai e eiaaoeyoeeiiiiai caaia aaiinoaca (?acenoaioiinoue eaieey?ia, eiee/anoai oaeoi?a Aeeeaa?aiaea, o?iiaioeeoia e eo ooieoeeiiaeueioth aeoeaiinoue, iieacaoaee eiaaoeia?aiiu). N iiiiuueth eino?oiaioaeueiuo iaoiaeia enneaaeiaaiey eco/aee iieacaoaee yeaeo?iea?aeeia?aoee, yoiea?aeea?aoee, ?aiaaiaoia?aoee, ?aiaacia?aoee, eiiuthieoeaaeueiie aeiiee?ineiiee, a oaeaea enneaaeiaaee iaoiii?oieiae/aneea eciaiaiey o oia?oeo io eaioinie?iciie eioaeoeee. A ia/aeueiii ia?eiaea caaieaaaiey ii/oe o iieiaeiu aieueiuo n eaioinie?ii auyaeaiu noauaeoeaiua e iauaeoeaiua ia?ooaiey na?aea/ii-ninoaeenoie nenoaiu (aiee a iaeanoe na?aeoea, ?anoe?aiea a?aieoe na?aeoea, nenoiee/aneee ooi, i?eaeooaiinoue oiiia, oaoeea?aeey, a?aaeeea?aeey, a?eoiey). Eiee/anoai eciaiaiee na?aea/ii-ninoaeenoie nenoaiu i?e iicaeiae ainieoaeecaoeee, eioi?ay nii?iaiaeaeaeanue ia?inoaieai eioieneeaoeeiiiiai neiae?iia, cia/eoaeueii oaaee/eaaeinue. Yeaeo?iea?aeeia?aoe/aneea ia?ooaiey i?iyaeyeenue eciaiaieai coaoea O e naaiaioa ST, ia?ooaieai ooieoeee aaoiiaoecia ieiea?aea, i?iaiaeeiinoe, a?eoieyie, eioieneeaoeeiiii-aeeno?ioe/aneei neiae?iiii. Iieacaoaee oeaio?aeueiie aaiiaeeiaieee i?iaeaiiino?e?iaaee, /oi o aieueiuo ia eaioinie?ic i?aiaeaaeae aeia?aeeiaie/aneee oei aaiiaeeiaieee, eioi?ue oa?aeoa?eciaaeny oaaee/aieai /anoiou na?aea/iuo nie?auaiee, oaea?iiai e nenoiee/aneiai eiaeaenia, nieaeaieai iauaai ia?eoa?e/aneiai nii?ioeaeaiey ninoaeia. Iaia?oaeaiu cia/eoaeueiua eciaiaiey ninoaeenoi-o?iiaioeeoa?iiai caaia aaiinoaca, eioi?ua i?iyaeyeenue oaaee/aieai ?acenoaioiinoe ninoaeenoie noaiee, aeoeaiinoe oaeoi?a Aeeeaa?aiaea, au?aaeaiiie o?iiaioeeoiiaieae e oaaee/aieai aaeaaceaiie e aa?aaaoeeiiiie aeoeaiinoe o?iiaioeeoia. Auyaeaii ia?ooaiea iee?ioee?eoeyoeee eae ia o?iaia iaeeeo ninoaeia, oae e ia aioo?ei?aaiiii o?iaia. I?e aenoieiae/aneii enneaaeiaaiee ai anao i?aaiao iaaethaeaeenue cia/eoaeueiua ?anno?ienoaa a nenoaia iee?ioee?eoeyoi?iiai ?onea. A ieiea?aea ?acaeaaeanue aaeeiaay aeeno?ioey e i/aaiaua iia?aaeaeaiey ea?aeeiieioeeoia, au?aaeaiiue ioae eioa?noeoeey e yenoaeaoeaii-i?iaeoeoeaiue i/aaiaue ieiea?aeeo. ?ac?aaioai e i?aaeeiaeai iaoiae ea/aiey aieueiuo eaioinie?icii n eniieueciaaieai aiaei?ioaeoi?a yoaiceeaoa iao?ey e i?aia?aoa noeioee?othuaai iaoaaiee/aneea i?ioeannu ?eaieneia a ni/aoaiee n eiiieaeniie oa?aieae. Aeaiiue iaoiae iicaieee iiauneoue yooaeoeaiinoue ea/aiey aieueiuo eaioinie?icii ca n/ao ii?iaeecaoeee i?iieoeaaiinoe ninoaeenoie noaiee, oaaee/aiey eiee/anoaa o?iiaioeeoia e eo ooieoeeiiaeueiie aeoeaiinoe. Iieacaoaee oeaio?aeueiie e ia?eoa?e/aneie aaiiaeeiaieee, nie?aoeoaeueiay ooieoeey ieiea?aea e iieacaoaee iee?ioee?eoeyoeee o aieueiuo eaioinie?icii naeaeaoaeuenoaiaaee i iieiaeeoaeueiii yooaeoa oa?aiee. Aeieacaii, /oi eniieueciaaiea ?ac?aaioaiiiai iaoiaea ea/aiey aeaao aiciiaeiinoue i?aaeoi?aaeeoue ?acaeoea aaii??aae/aneiai neiae?iia e ia?ooaiee na?aea/ii-ninoaeenoie nenoaiu o aieueiuo eaioinie?icii, a i?e eo iaee/ee aeinoe/ue auno?iai e au?aaeaiiiai eeeie/aneiai yooaeoa. Eeth/aaua neiaa: eaioinie?ic, aaiinoac, iee?ioee?eoeyoeey, ieiea?ae, ea/aiea, yoaiceeao iao?ey, ?eaienei. ANNOTATION V.F. Pjuryk. Cardiovascular Disorders in the Patients Sufferina from Leptospirosis and Methods of their Correction Thesis for a marter's degree in the speciality of infection diseases (14.01.13). - The Gromashevsky Research Institute for Epidemiology and Infection Disease, Kyiv, 1999. It was established that leptospirosis causes damages in vascular-thrombocytic homeostasis links resulting in impairments in microcirculation both at the level of small vessels and the inner organic level, central hemodynamics indices becoming worse and tissue hypoxia developing. At the same time one can observe cardio vascular system impairments characterized by development of such syndromes as intoxicodystrophic conductivity impairments and on arrhythmic one. A clinicolaboratory study was undertaken to reveal the optimal combination of the traditional therapy with etamsylate natrii and riboxin at the background of the traditional therapy. The proposed treatment enables the doctor to prevent the hemorrhagic syndrome development, the cardiovascular system impairment and at their availability to achieve a guick and pronounced clinical effect.

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