2

IINOA?NOAI IOI?IIE CAeI?IAss OE?AIE

EEANUeEEE IAOEIAI — AeINEIAeIEE IINOEOOT IOIEA?EIAIEIAI

i. i?io. I.N. EIEIIIE*AIEA

Ia i?aaao ?oeiieno

IA?ACOeIA IAI? AAIIAAeIEIAE*

OAeE 616.22-0066-008.5-085-089

?IC?IAEA NIINIAIA EIEOAAIIss OAI?EO

IA ?AE AI?OAII NEEAAeEIAI EIEAEICAOeI

14.01.19 — ioi?eiiea?eiaieia?y

AAOI?AOA?AO

aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

EEA — 1998

Aeena?oaoe??th ? ?oeiien.

?iaioo aeeiiaii a Eeanueeiio iaoeiai-aeineaeiiio inoeooo ioiea?eiaieia
i. i?io. I.N.Eieiie/aiea IIC Oe?a?ie.

Iaoeiaee ea?aiee: aeieoi? iaaee/ieo iaoe Eoea/ A?a?i Aaioeaeiae/,
caa?aeoaa/ a?aeae?eaiiy iieieia?? Ee?anueeiai IAe? ioiea?eiaieia??.

Iooeei iiiiaioe: aeieoi? iaaee/ieo iaoe Aaecia ?onoai Aaeeeueiae/,

i?ioani? eaoaae?e ioi?eiiea?eiaieia?? Ee?anueei?

aea?aeaaii? iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe

?i. I.E.Ooieea

aeieoi? iaaee/ieo iaoe, i?ioani?

O?io?iaiei Ieeiea I?ieiiiae/, caa?aeoaa/ eaoaae?e ioi?eiiea?eiaieia??
Aeiiaoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i. I.Ai?ueeiai

I?iaaeia onoaiiaa: Iaoeiiaeueiee iaaee/iee oiaa?neoao i. aeaae.

I.I.Aiaiiieueoey.

Caoeno aeena?oaoe?? aaeaoaeaoueny “ 15 ” a?oaeiy 1998 ?. i 12 aiaeei ia
canaeaii niaoeaeciaaii a/aii ?aaee Ae 26.611.01 Eeanueeiai
iaoeiai-aeineaeiiai inoeoooo ioiea?eiaieia?? i. i?io. I.N.Eieiie/aiea
(252057, i.Eea, aoe. Ciieia?/ia, 3).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Ee?anueeiai
iaoeiai-aeine?aeiiai ?inoeoooo ioiea?eiaieia?? ?i. i?io.
I.N.Eieii?e/aiea.

Aaoi?aoa?ao ?icneaii “31” aeiaoiy 1998 ?.

A/aiee nae?aoa?

niaoeaeciaaii a/aii ?aaee

eaiaeeaeao iaaee/ieo iaoe A. I. ?ICEEAAeEA

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueinoue i?iaeaie

Iaeith c i?iaaeieo i?iaeai EI?-iieieia o?o?a/ia eeoaaiiy ?aeo ai?oai.
Iacaaaeath/e ia onioe a aeaaiinoeoe? ?aeo ai?oai, iniiaia iana oai?eo
caa?oaoueny aei e?ea?y c caiouaieie (III-IV) noaaeyie caoai?thaaiiy
(A.E.Oeuaaiia, 1971; TH.N. Aaiao?a, 1974; Ae.E.Oa?ania, N.I.Eai/aiei,
1978; I.A.Aeothoeeee, 1991; A.N.Aeoa?ia, 1996; ?.A.Aaucia, 1997).

Ooieoeiiaeueia o?o?ay ?aeo ai?oai ye iaeei c iniiaieo iaoiaea eeoaaiiy
canoiniaooueny o oai?eo c I-II noaaeyie iooeeiiiai i?ioeano
(A.N.Iiainia, 1966; E.A.Aooiai, 1970; A.A.Oaeaei, 1975; Y.A.Eoea/, 1995;
N.I.Oui/oe, 1997; Leroux-Robert, 1967; Calcaterra, 1987; Dubrenil,
1993).

A inoaii ?iee ?ic?iaeaii oeeee ?yae ooieoeiiaeueieo
?aeiino?oeoeaii-aaeiiaethaaeueieo iia?aoee aeey eeoaaiiy oai?eo ia ?ae
ai?oai III-IV noaae? (A.O.Iaeue/oi, 1975; A.A.*aniieia, 1985;
I.A.Aeothoeeee, 1993; A.E. Eei/eoei, 1996; ?.A.Aaucia, 1997; Biller,
1986; Eliachar, 1987; Laraqui, 1994).

Aei oeueiai /ano inoaoi/ii ia ae?oaia ieoaiiy i?i aea? iaaiiai niiniao
ea?eiaiieanoeee i?e ?acaeoeyo ai?oai c i?eaiaeo ?aeo (A.E.Oeuaaiia,
E.A.Aooiai, 1976; A.I.Ieueoaineee, 1987; A.A.Oaeaei, 1990; A.A.Oaioo?ia,
1991; Dedo, 1975; Kambic, 1976; Krajina, 1990; Laccourreye, 1995).

Caaaeyee ai?iaaaeaeaiith iiaeo niiniaa ooieoeiiaeueieo iia?aoee
cyaeeanue iiaeeeanoue aaeiiaethaaoe ao?a/ai ooieoe ai?oai, ia?o ca ana
aieiniao oa aeeoaeueio, ui ia aaaeeeaa cia/aiiy aeey iaaeeei-nioeaeueii
?aaaeoaoe oai?eo ia ?ae ai?oai (E.A.Aooiai, 1977; N.E.Oaioaiiaa, 1985;
A.A.Aei?iaeia, 1988; N.I.Nieieaiei, 1991; A.A.Eaoaeaaa, 1991;
N.I.Oui/oe, 1991; Padovan, 1975; Klein, 1977; Hirano, 1987; Laccourreye,
1991).

Iacaaaeath/e ia onioe ea?eiaiiieieia, i?iaeaia ai?ioueae c ?aoeeaeeaaie
ceiyenieo iiaiooai?aiue, ye aeieeathoue iney eeoaaiiy ia?aeiiiai
iooeeiiiai ina?aaeea, caeeoaoueny aeooaeueiith.

A ca’yceo c? ci?iith caaaeueiiai i?iiaiaaiai oiio i?ney aaa??? ia *AAN
oa a?aeiiaith oai?eo a?ae i?iaaaeaiiy i?iiaiaaiai e?eoaaiiy ?aeo
ai?oai?, iniaeeai aaaeeeaei ? iiooe iiaeo iai?iiaiaaeo niiniaa
aeaaoaecaoe iooeeiieo eeoei ia inoe aeaeaeaiiiai ceiyeniiai
iiaiooai?aiiy, iaeiei c yeeo ? iaoiae oioiaeeiai?/ii? oa?ai??
(A.I.Ao?eiiae/, 1987; I.I.AEa?eiaa, 1988; E.N.Iaeueiee, 1995;
I.E.Neiaaeeei, 1996; Canti, 1983; Dougherty, 1984; Abramson, 1986;
Dilkes, 1996).

Ana oea naae/eoue i?i aeooaeueinoue aeineaeaeaiue, i?enay/aieo
ooieoeiiaeueie o?o?a ?aeo ai?oai iiooeo iiaeo aoaeoeaieo iaoiaea
eeoaaiiy ?aaaeoaoe oai?eo ia ?ae ai?oai?.

Iaoa aeineaeaeaiiy

?ic?iaeoe ? ai?iaoaaoe iia? iaoiaee e?eoaaiiy oai?eo ia ?ae ai?oai?
na?aaeeiii? eieae?caoe?? (o??o?a?/iee ? iaoiae ?io?aiia?aoe?eii?
oioiaeeiai?/ii? oa?ai??) aeey i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy oai?eo
ia ceiye?ni? iooeeie ai?oai?.

Caaea/? aeineaeaeaiiy

1. ?ic?iaeoe niina aaiea?eiaaeoii aeey e?eoaaiiy oai?eo ia ?ae
neeaaeeiaiai a?aeae?eo ai?oai II — III noaae?? (T2-3N0M0).

2. Aeaoe eei/io ioeieo aoaeoeaiino ?ic?iaeaiiai iaoiaeo o ii??aiyii? c
ioeie niiniaaie ?acaeoe ai?oai.

3. Aeineaeeoe aieiniooai?thth/o ooieoeth ai?oai i?ney aai?ea?eiaaeoii??
c canoinoaaiiyi no/anieo aia?aoieo iaoiaea.

4. I?iaanoe eei/i aeineaeaeaiiy aoaeoeaiino canoinoaaiiy io?aiia?aoeeii
oioiaeeiai/ii oa?ai (IOAeO) i?e ooieoeiiaeueie o?o?a oai?eo ia ?ae
ai?oai.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a

1. ?ic?iaeaii ai?iaiaaii iiaee niina o?o?a/iiai eeoaaiiy oai?eo ia ?ae
ai?oai (iaoaio ? 7176 A aae 30.06.95 ?.).

2. A?aei?/aii iie?auaiiy oiiaoi?ii? ooieoe?? o oai?eo ia ?ae ai?oai?
iney ooieoeiiaeueieo ?acaeoee ?c canoinoaaiiyi iiaiai niiniao
aai?ea?eiaaeoii??.

3. Canoinoaaiiy ?io?aiia?aoe?eii? oioiaeeiai?/ii? oa?ai?? (?OOAe) i?e
ooieoe?iiaeueieo ?acaeoe?yo c i?eaiaeo ?aeo ai?oai? cia/ii ciaioo?
/anoioo aeieeiaiiy ?aoeeaeea?a ? iaoanoac?a.

I?aeoe/ia cia/aiiy ?iaioe

1. Cai?iiiiiaaiee iaie niina ?aeiino?oeoeaii iia?aoe ia ai?oai c
i?eaiaeo ?aeo (EIAe?IE-2) aea aenie ooieoeiiaeuei ?acoeueoaoe, ciaioo
iaaeaeecaoeth oai?eo ni?ey o nioeaeueie ?aaaeoaoe.

2. Aiaec oiiaoi?ii ooieoe ca aeiiiiiaith aia?aoii-i?ia?aiiiai eiiieaeno
aeicaiey iaaeoeaii ioeieoe aoaeoeainoue ?cieo niiniaa ?acaeoe ai?oai i?e
o?aaeaii ?aeii.

3. Iaoiae IOAeO ia aaeeea i?aeoe/ia cia/aiiy ? ? iaoiaeii aeai?o i?e
eeoaaii EI?-iieieia/ieo oai?eo.

Caycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie

?iaioo aeeiiaii caaeii c ieaiii iaoeiai-aeineaeieo ?iao Eeanueeiai
IAeI ioiea?eiaieia i. i?io. I.N.Eieiie/aiea o ?aieao oai:

1. “?ic?iaeoe iia oa oaeineiiaeeoe nioth/ o?o?a/i iaoiaee eeoaaiiy
oiiaoi?ii ?aaaeoaoe oai?eo ia ?ae ai?oai “, OAeE
616.22-008.5-089.616.22-006.6-085.

2. “?ic?iaeoe, ai?iaoaaoe ai?iaaaeeoe a o?o?a/io i?aeoeeo
io?aiia?aoeeio oioiaeeiai/io oa?aith c aeei?enoaiiyi ?cieo oeia eaca?a
oioinaineaecaoi?a aeey eeoaaiiy ceiyenieo iooeei EI?-i?aaia“, OAeE
616.21-006:(615.831+615. 849.19).

Ai?iaaaeaeaiiy a i?aeoeeo

Iiaee aoaeoeaiee niina o?o?a/iiai eeoaaiiy oai?eo ia ?ae ai?oai, iaoiaee
oiiaoi?ii ?aaaeoaoe io?aiia?aoeeia oioiaeeiai/ia oa?aiy ai?iaiaai
ai?iaaaeaeai a niaoeaeciaaieo eeieao i.Eeaa (EI?-iieieia/ia aaeaeeaiiy
aaeaeeaiiy ?aeiino?oeoeaii-aaeiiaethaaeueii o?o?a Eeanueeiai IAeI
ioiea?eiaieia i.i?io.I.N.Eieiie/aiea), Aeii?iiao?ianueei iaeanoii eei/ii
eea?i i. I.I.Ia/ieiaa, E?eai?icueeiio inueeiio iieiaeeniaina?.

Io?eiaii iaoaio ia aeiaoae iiaiai niiniao o?o?a/iiai eeoaaiiy oai?eo ia
?ae ai?oai (? 7176 A aae 30.06.95 ?.), yeee ai?iaaaeaeaii o
EI?-iieieia/iiio aaeaeeaii Eeanueeiai IAeI ioiea?eiaieia i. I.N.
Eieiie/aiea o aaeaeeaii ai?iiiicaeaaeieo iooeei, aieiae oe
E?eai?icueeiai inueeiieiaeeniaina?o.

Iniaenoee aianie caeiaoaa/a

Aaoi? naiinoeii i?iaiaeea aaea?, eei/ia ianoaaeaiiy eeoaaiiy oai?eo ia
?ae ai?oai neeaaeeiai eieaecaoe II-III noaae.

Noaoenoe/ia ia?iaea, aiaec ocaaaeueiaiiy io?eiaieo ?acoeueoaoa
aeineaeaeaiiy, a oaeiae ioi?ieaiiy ?iaioe aeeiiaii aeena?oaioii.

Ai?iaaoey ?acoeueoao?a aeena?oaoe??

Iaoa?aee aeena?oaoe aeiiiaaeaeeny iaaiai?thaaeeny ia canaeaiiyo
iaoeiaeo oiaa?enoa ioiea?eiaieiaa iaoeiai-i?aeoe/ieo eiioa?aioeyo
iieieiaa i.E?eaiai ?iao (1993-1997 ??.), VIII ccae ioiea?eiaieiaa Oe?aie
(Eea, 1995), ?anioaeeainueee iaoeiai-i?aeoe/ie eiioa?aioe “No/ani
i?iaeaie EI?-iieieia“ (Iaeana, 1997), iaoeiai-i?aeoe/ie eiioa?aioe,
i?enay/aie 100-?//th c aeiy ia?iaeaeaiiy i?io. I.N.Eieiie/aiea (Eea,
1998).

Ioaeeaoe

Ca iaoa?aeaie aeena?oaoe iioaeeiaaii 6 iaoeiaeo ?iao ? 1 aeiaoae.

Iai no?oeoo?a aeena?oaoe??

Aeena?oaoeth aeeeaaeaii ia ___ noi?ieao iaoeiiieniiai oaenoo. Aiia
neeaaeaoueny c anooio, 6 aeaa, iaaiai?aiiy, aeniiaea, i?aeoe/ieo
?aeiiaiaeaoee, iieaae/eea eoa?aoo?e, ui inoeoue ___ iaeiaioaaiue, c yeeo
____ ?iaioa ao/eciyieo ____ ca?oaaeieo aaoi?a. Aeena?oaoey ?ethno?iaaia
___ ?enoieaie ? ___ oaaeeoeyie.

Cino ?iaioe

Iaoa??aee ? iaoiaee aeine?aeaeaiiy

A iniiao ?iaioe iieeaaeaii ?acoeueoaoe eeoaaiiy 221 oai?eo ia ?ae ai?oai
neeaaeeiai eieaecaoe (146 – aea/aiiy aoaeoeaiino? iiaiai o??o?a?/iiai
iaoiaeo ? 75 – ai?iaaoe?y ?OAeO).

Aiaec ooieoeiiaeueieo ?acaeoee ai?oai i?e ? o?aaeaii ?aeii i?iaaaeaii o
146 oai?eo o aoe aae 30 aei 70 ?iea, c ieo /ieiaea – 141, aeiie – 5.
Iniiaia iana oai?eo aoea o aoe aae 41 aei 70 ?iea – 130 /ieiae (89,1 %).

Ca noaaeyie caoai?thaaiiy oai? ?iciiaeeyeenue oaeei /eiii: T2N0M0 – 45
oai?eo, ui noaiiaeoue 30,8 %, T3N0M0 – 101 iaoeio.

Ani oai?ei i?iaaaeai ?ci niiniae ooieoeiiaeueieo ?acaeoee aiie aoee
?iciiaeeai ia o?e a?oie. Ic 146 iia?aoee 121 aeeiiaii o EI?-iieieia/iiio
aaeaeeaii Eeanueeiai IAeI ioiea?eiaieia 25 – E?eai?icueeiio
inueeiieiaeeniaina?. 47 iia?aoe?e i?iaaaeaii o iaoe iiaeeoeaoe
(EIAeII-2), 49 – ca iaoiaeii EIAeII-1, a c 50 oai?eo o?aouei a?oie 39
aeeiiaii aieiao ?acaeoeth ai?oai, 7 – ia?aaeiuei-aieiao ?acaeoeth, o 4
aeiaaeeao — i?iaaaeaii io niiniae aa?oeeaeueieo ?acaeoee i?e ?aeo
neeaaeeiaiai aaeaeeo ai?oai.

Ani oai?ei i?iaiaeeeinue caaaeueiieei/ia ianoaaeaiiy niaoeaeueia
ianoaaeaiiy EI?-i?aaia: iai?yia ea?eiaineiiy c aiinth, ?aioaaiia?aoy
oiiia?aoy ai?oai, aeioee no?aaioiaeo; niaoeaeuei ianoaaeaiiy ooieoee
ai?oai.

I?e aeeiiaii aeaii ?iaioe aeei?enoiaoaaeanue iaoiaeeea eiiithoa?ii
ia?iaee aeaieo aeineaeaeaiiy eeoaaiiy oai?eo ia ?ae ai?oai neeaaeeiai
eieaecaoe c canoinoaaiiyi ?cieo niiniaa ooieoeiiaeueieo iia?aoee. Ia aac
iieieia/iiai aaeaeeo Eeanueeiai IAeI ioiea?eiaieia i. i?io.
I.N.Eieiie/aiea ?ic?iaeaii i?ia?aio “Cancer-2”, yea neeaaeaoueny c aeaio
/anoei. Ia?oa /anoeia inoeoue a nia ianii?oi aeai ia eiaeiiai oai?iai,
aeai aiaiiaco, iaoiaee aeaaiinoeee, eeiee, oa?aeoa? i?iaaaeaiiai
eeoaaiiy eiai ?acoeueoaoe. Ae?oaa /anoeia ?ac?iaeaia ia iniia ia?oi
aeicaiey i?iaiaeeoe ii?aiyeueiee aiaec ?cieo niiniaa ooieoeiiaeueieo
?acaeoe ai?oai, noaoenoe/io ia?iaeo aeaieo ?acoeueoaoa eeoaaiiy.

Iniiaiith iaoiaeeeith aeaii ?iaioe niina o?o?a/iiai eeoaaiiy ?aeo
ai?oai III coaae neeaaeeiai eieaecaoe (iaoiae ?acaeoe?? ai?oai?
EIAe?I-2) (iaoaio ? 7176 A a?ae 30.06.95 ?.).

Niina yaey niaith iiao iaoiaeeeo ?acaeoe ai?oai i?e o?aaeaii ?aeii
inoeoue a nia aeaeaeaiiy iieiaeie i?aaio c caa?aaiiyi ieanoeiee
ueoiaeaeiiai o?yua ia aioe o?aaeaiiy ciaioiuei iaaeo?yuieoe oa
ni?yiiaai ia iaeneiaeueia caa?aaeaiiy ii?ooaii? ooieoe?? ai?oai? c
aeio?eiaiiyi i?eioeeia ?aaeeeaecio.

C iaoith ioeiee nooiaith caa?aaeaiiy oiiaoi?ii ooieoe iney
cai?iiiiiaaiiai iaie iaoiaeo oa ioeo niiniaa ?acaeoe ai?oai ie
canoinoaaee iiaeeoeiaaiee aia?aoii-i?ia?aiiee eiiieaen aeey ianoaaeaiiy
iiaiiai neaiaeo. Inoaiie yaey niaith i?eno?e aaiaeo/aeaiaeo i?ia?aiiiai
aiaeco iiaiiai neaiaeo. Eiiieaen noai?aii ia aac ia?niiaeueiiai
eiiithoa?o IBM PC/AT. Caien iiaiiai neaiaeo i?iaaaeaii ia iaaioioii.

Caien aieino i?iaiaeeany oiiaoeth aieinieo caoea “A”, “I”, “A”, “I”, “O”
c ianooiiei aiaecii caoeiaiai neaiaeo aia?aoii-i?ia?aiiei eiiieaenii.

Iaoiaeeea caieno aieiniaiai neaiaeo aoea oaeith: aaenoaiue aae aoa
iaoeioa aei ie?ioiio noaiiaeea 20 ni. Iioaineainoue aieino — 40 aeA.

Eiiieaen aeicaiey io?eiaoe i?iaanoe niaeo?aeueiue aiaec aieino ia iniia
eeueenii /anoioii oa?aeoa?enoeee oi?iaio, eiaooeioa aa?aoe oa iayaiino
aeniei/anoioieo iea.

Aeey oa?aeoa?enoeee aieiniai ooieoe ie aeiaeaoeiai canoiniaoaaee
iaoiaeeeo aea/aiiy /ano iaeneiaeueii oiiaoe. ?acoeueoaoe ioeithaaee,
aeoiaey/e c oiai, ui /an iaeneiaeueii oiiaoe o /ieiaea noaiiaeoue 18-20
n, o aeiie – 16-18 n.

?ic?iaeee canoinoaaee aeeoa?aioeaeueio oiiiiaaee/io oa?aith iaeii/anii
c caiyooyie eeoaaeueiith oceoeueoo?ith o oai?eo iney ?acaeoee ai?oai c
iaoith iieioaiiy aieiniooai?thth/i ooieoe.

Aeey iie?auaiiy ?acoeueoaoa i?ioeaiiooeeiiiai eeoaaiiy oai?eo ia ?ae
ai?oai o II-III noaae ai?iaaaeeee iaoiaeeeo io?aiia?aoeeii oioiaeeiai/ii
oa?ai (IOAeO). Oioinaine-aecaoi?ii aoei aeei?enoaii ?ic/ei iaoeeaiiaiai
neiueiai. Inoaiie aaiaeeee ioeueo?aoeeii o eiaea ?aie (1 ie 0,4%
?ic/eio) iney oeueiai i?iaiaeeany eaca?iee aieea aaia?aoi?ii AIE-111 c
aeiaaeeiith oaee aei?iiithaaiiy 633 ii ueueinoth iiooaeiino i?iiaiaaiai
iioieo a ieyi 25-30 iAo ia i?ioyc 5 oa.

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy

Iaie i?iaaaeaii 47 iia?aoee c i?eaiaeo ?aeo ai?oai neeaaeeiai eieaecaoe
c canoinoaaiiyi iiaiai niiniao ooieoeiiaeueii ?acaeoe ai?oai o iaoe
iiaeeoeaoe (EIAe?I-2) (iaoaio ? 7176 A).

Niina o?o?a/iiai eeoaaiiy ?aeo ai?oai aae?ciyoueny oei, ui i?e
aeaeo?i?acaeoe ai?oai ia aioe a?aaeaiiy caa?aa?oueny aa?oie e?ae
ieanoeiee ueoiaeaeiiai o?yua ea?eiaiieanoeea aeeiio?oueny caa?aaeaiith
o?yuiaith ieanoeieith ciaioiueith iaaeo?yuieoeath.

I?e aeei?enoaii iiaiai niiniao ?acaeoe ai?oai i?e o?aaeaii ?aeii ie
io?eiaee oae? ooieoeiiaeuei ?acoeueoaoe (oaae.1).

Oaaeeoey 1

Ooieoeiiaeuei ?acoeueoaoe ?acaeoee ai?oai

Ooieoe?iiaeuei? ?acoeueoaoeNiiniae ?acaeoe??Iia?aoe?? EIAe?I-2Iia?aoe??
EIAe?I-1?io?
?acaeoe??Aeaeaitheyoe?yOae403840I?71110Aieiniooai?aiiyAeenoii?y444345Aoi
i?y365EiaoaiiyCaa?aaeaii424043Ii?ooaii597AeeoaiiyAeinoaoi?424043Noaiic59
7

Aaiea?eiaaeoiiy o iaoe iiaeeoeaoe (EIAeII-2) aeicaieeea aeaeaithethaaoe
oai?eo o 85,1% aeiaaeea, caa?aaoe aieiniooai?aiiy a 93,6%, caoenio
ooieoeth oa aeeoaiiy – a 89,4%, ui caaacia/o iaeaeueo iiaiioeiio
?aaaeoaoeth a ii?aiyii c ioeie niiniaaie ooieoeiiaeueieo ?acaeoee.

A ?acoeueoao i?iaaaeaieo 2-o 5-?/ieo niinoa?aaeaiue ca oai?eie ono a?oi
ie io?eiaee oaee ?acoeueoaoe eeoaaiiy (oaae. 2, 3).

Oaaeeoey 2

2-o ?/i ?acoeueoaoe eeoaaiiy oai?eo

Niin?a ?acaeoe??E?euee?noue oai?eo?aoeeaeeae a ai?oai?Ion a ?aa.
e/aA?aeaeae. ionIiia? a?ae ?io. caoa.I?iae. 2 ?ieeC ieo aac ?aoeeaeea?a
? ionIia?aoe?y EIAe??I-24762-142

(89,4%)38

(80,2%)Iia?aoe?y EIAe?I-1491261139

(79,6%)29

(59,2%)?io? ?acaeoe??50153-140

(80%)31

(62,0%)Anueiai146331113121

(82,9%)98

(67,1%)

Oaaeeoey 3

5-oe ?/i ?acoeueoaoe eeoaaiiy oai?eo

Niin?a ?acaeoe??E?euee?noue oai?eo?aoeeaeeae a ai?oai?Ion a ?aa.
e/aA?aeaeae. ionIiia? a?ae ?io. caoa.I?iae. 5 ?ie?aC ieo aac ?aoeeaeea?a
? ionIia?aoe?y EIAe??I-2471031334

(72,3%)30

(63,8%)Iia?aoe?y EIAe?I-1491782230

(61,2%)20

(40,8%)?io? ?acaeoe??502041232

(64%)24

(48,0%)Anueiai14647154796

(65,7%)74

(50,7%)

2-o ?/ia aeaeeaaiiy o oai?eo iney aaiea?eiaaeoii o iaoe iiaeeoeaoe
noaiiaeoue 89,4%, i?e na?aaeio iieacieeao 82,9%.

5-oe ?/i ?acoeueoaoe eeoaaiiy i?e aeei?enoaii iiaiai niiniao
ooieoeiiaeueii ?acaeoe ai?oai noaiiaeee 72,3%, i?e na?aaeio iieacieeao –
65,7%.

An?i oai?ei aoei i?iaaaeaii eiia?iiaaia e?eoaaiiy c iia?aoeaiei
ao?o/aiiyi ia 1-io aoai?.

Iieacaiiy aei eiiaiiaaiiai eeoaaiiy c iia?aoeth ia I aoai aoee
ianooiieie:

— iooeeiiee noaiic ai?oai;

— ?iciianthaeaeaiiy iooeeie ia iaeneeaaeeiaee aaeaee ai?oai ii?aaia
oeoii/ee;

— ioeueo?aoeaiee oa ioeueo?aoeaii-ae?aceiaee oa?aeoa? ?inoo iooeeie;

— iaei?ooiinoue aai ia?ooiinoue iieiaeie ai?oai ia aioe o?aaeaiiy.

C 146 i?ieeiaaieo iaie oai?eo aeey aea/aiiy oiiaoi?ii ooieoe o
1995-1996 ??. aoei acyoi o?e a?oie caaaeueiith eeueenoth 30 /aeiae. Aiie
aoee ?icaeeai a caeaaeiino aae oa?aeoa?o i?iaaaeaiiai iia?aoeaiiai
ao?o/aiiy.

O ia?oe a?oi 10 oai?ei aeeiiaii ?ci niiniae aa?oeeaeueieo ?acaeoee
ai?oai: o?iioi-eaoa?aeueieo – 3, o?iioaeueia – 1, eaoa?aeueieo ?acaeoee
ca Iiainiaei – 2, aaiea?eiaaeoiie ca Gluck – 2, ioeo ?acaeoee – 2.

A ae?oae a?oi 10 oai?ei i?iaaaeaii iia?aoeaia ao?o/aiiy c aeei?enoaiiyi
cai?iiiiiaaiiai iaie niiniao aaiea?eiaaeoii (EIAeII-2).

Oai?ei o?aouei a?oie aeeiiaii 10 iia?aoee o iiaeeoeaoe EIAeII-1.

Aeineaeaeaiiy aieiniooai?thth/i ooieoe i?iaiaeeeinue iaie o ?aiiueiio
ineyiia?aoeeiiio ia?iae (i?ioyaii aeaio inyoea iney iia?aoeaiiai
ao?o/aiiy).

O ia?oe a?oi oai?eo (io aa?oeeaeuei ?acaeoe ai?oai) (na?aaeie ae
ianoaaeaieo – 51 ?e) aoiith aeyaeaii o 6 c 10. O ae?oae a?oi c 10
iaoeioa aaenooinoue ao/ii iiae aaei/aii o 4 /ieiae (EIAeII-2). Na?aaeie
ae oai?eo noaiiaea 50 ?iea.

A o?aoe a?oi oai?eo (iia?aoey EIAeII-1) (na?aaeie ae ianoaaeaieo – 50
?iea) aoiith aaei/aii o 7 c 10.

Aiaecoth/e aieiniaee neaiae c aeei?enoaiiyi cia/aiue /anoioiiai
?iciiaeeo eiaooeioo aa?aoe ie io?eiaee oae ?acoeueoaoe o o?ueio a?oiao.

I a?oia (io ?acaeoe): c 10 ianoaaeaieo oai?eo oeueee o iaeiiai an o?e
oi?iaioe aeeaaeaeenue a ii?io /anoioiiai ?iciiaeeo, aea eiaooeio aa?aoe
o?aouei oi?iaioe aoa aenieei (56 %) , ui naae/eei i?i ianoaaeueinoue oe
oi?iaioe. O ?aooe oai?eo ia?oa oa ae?oaa oi?iaioe ia oeeaaeaeenue o
ii?io /anoioiiai ?iciiaeeo iaee aenie eiaooeioe aa?aoe (aeueoa 40%).

II a?oia (EIAeII-2): o aeaio oai?eo oi?iaioe aeeaaeaeenue a iaae
ii?iaeueiiai /anoioiiai ?iciiaeeo, aea iaee aenie eiaooeioe aa?aoe (48%
oa 56 %). O /ioe?ueio iaoeioa iaeia oi?iaioa, a o ?aooe — aea oi?iaioe
ia aeeaaeaeenue a /anoioio ii?io. Eiaooeio aa?aoe o ieo eieeaaany aae 14
aei 77 %.

III a?oia (EIAeII-1): o iaeiiai oai?iai oi?iaioe oeeaaeaeenue o
ii?iaeueiee /anoioiee aeaiacii, aea eiaooeio aa?aoe o?aouei oi?iaioe aoa
iaaeoi aaeeeei (68%). O /ioe?ueio iaoe??io?a /anoioie ii?i ia
aaeiiaaeaea aeiaeia oi?iaioa, o aeaio oai?eo – aea oi?iaioe o o?ueio
iaoeioa /anoioie ii?i ia aaeiiaaeaea aeiaeia c oi?iaio. Eiaooeio aa?aoe
eieeaaany o iaaeao aae 25 aei 60 %.

Ia iniia i?iaaaeaiiai aiaeco niaeo?ia?ai aieino iney ?cieo
ooieoeiiaeueieo ?acaeoe ai?oai c i?eaiaeo ?aeo ie io?eiaee aeai i?i
iaeneiaeuei aieinicaa?aath/ iiaeeeaino i?e aeei?enoaii iaoiai niiniao
aaiea?eiaaeoii.

Aeiaeaoeiai iaie i?iaaaeaii aea/aiiy /ano iaeneiaeueii oiiaoe a ono
o?ueio a?oiao oai?eo iney iia?aoeaiiai ao?o/aiiy iney oiiiiaaee/iiai
eeoaaiiy. ?acoeueoaoe niinoa?aaeaiue iaaaaeai? o oaae. 4.

Oaaeeoey 4

Aeineaeaeaiiy /ano iaeneiaeueii oiiaoe

*an iaeneiaeueii? oiiaoe?? (n)Aei oiiiiaae??I?ney oiiiiaae??I a?oia
(?io? ?acaeoe??)13,7014,80II a?oia (iia?aoe?? EIAe?I-1)14,0715,47III
a?oia (iia?aoe?? EIAe?I-2)14,1015,90

I?e i?iaaaeaii eeueeniiai aiaeco na?aaeiueiai /ano iaeneiaeueii oiiaoe o
oai?eo iney ?cieo niiniaa ?acaeoe ai?oai c i?eaiaeo ?aeo e?au yeni
?acoeueoaoe io?eiai i?e canoinoaaii iiaiai niiniao aaiea?eiaaeoii o iaoe
iiaeeoeaoe c aeei?enoaiiyi aeeoa?aioeeii oiiiiaaee/ii oa?ai.

Iney i?iaaaeaiiy aaeiiaii oiiiiaae /a?ac 2-3 inyoe o aeueoino iaoeioa
aeinyaiaii iie?auaiiy aieiniooai?thth/i ooieoe ai?oai, ui aoei
caoeniaaii i?iaiaeciaaii ia niaeo?ia?aiao.

Caeueoaiiy aiieooaee iniiaieo oi?iaio aieiniaiai neaiaeo, cia/ia
ciaioaiiy eeueeino aeniei/anoioieo ooia oa cieaeaiiy eiaooeioa aa?aoe
oiiai naae/eei i?i noaaecaoeth aieino o oai?eo.

Aeey eei/ii ai?iaaoe io?aiia?aoeeii oioiaeeiai/ii oa?ai (IOAeO) iaie
niinoa?aaeenue 75 oai?eo ia ?ae ai?oai T2-3N0M0 neeaaeeiai eieaecaoe. An
iaoeioe – /ieiaee. C ieo 38 oai?eo caa?ioeinue o T2N0M0 noaae
caoai?thaaiiy, 37 iaoe??io?a – o T3N0M0 noaae??. I?aeoe/ii o ano iaoeioa
iaee inoea i?ioeiieacaiiy aei i?iaaaeaiiy i?iiaiaai oa?ai o ieai
eiiaiiaaiiai eeoaaiiy. An oai? i?iiia?iaai o 1993-1994 ??. ?icaeeai ia
o?e a?oie ii 25 /ieiae.

I. Iniiaia a?oia. IOAeO i?iaiaeeeanue iney aeaeaeaiiy ia?aeiiiai
iooeeiiiai ina?aaeea. A ineyiia?aoeeio ?aio aaiaeeee 0,4% ?ic/ei
iaoeeaiiaiai neiueiai iaeaeaaaee eaca?iiio aieeao ?aio ia i?ioyc 5 oa.

II. Eiio?ieueia a?oia ?1. Oai?ei oe a?oie iney aeeiiaiiy iia?aoe eiaea
iooeeie ii?iiithaaee i?iiaiai eaca?o caaeii iaoiaeeee IOAeO, aea
oioinaineaecaoi? (iaoeeaiiaue neie) ia aaiaeeany.

III. Eiio?ieueia a?oia ?2. Iaoeioai i?iaiaeeeinue oeueee iia?aoeaia
ao?o/aiiy.

Aeeiai/ia niinoa?aaeaiiy ca oai?eie caeenithaaeinue i?ioyaii 5-oe ?iea.

Na?aae oneeaaeiaiue o ?aiiueiio ineyiia?aoeeiiio ia?iae ia 2-3 aeiao
aaei/aany iacia/iee iaa?ye neeciai iaieiiee ai?oai o aeaeeueeio oai?eo
ono a?oi (a?aeiinii a ??ai?e i???).

Iacia/ia a?iceaia e?iaioa/a aaei/aia o aeaio oai?eo ia?oi oa ae?oai
eiio?ieueieo a?oii. Aaiinoac i?iaaaeaii eiina?aaoeaieie iaoiaeaie.

Caaiiiy ineyiia?aoeeii ?aie aac ioeoaaiiy aaei/aeinue a iniiaie a?oi c
canoinoaaiiyi IOAeO.

?aoeeaeeaoaaiiy, iaoanoacoaaiiy oa nia?oinoue ca 3 oa 5 ?ie?a iaaaaeaii
a oaae. 5.

Oaaeeoey 5

Oa?aeoa?enoeea oai?eo ia ?ae ai?oai? ? ?acoeueoaoe e?eoaaiiy

a iniiai?e ? eiio?ieuei?e a?oiao

Eaoaai??? oai?eoA?oie oai?eoIniiaia (?OAeO)Eiio?ieueia ?1

(II+EACA?)Eiio?ieueia ?2 (II)E?euee?noue oai?eo252525A?e (?ie?a)35 –
6237 – 6333 – 60Noaae?? caoai?thaaiiy
(TNM)T2N0M0131213T3N0M0121312Oneeaaeiaiiy i?neyiia?aoe?eiiai
ia??iaeoIaa?ye neeciai? iaieiiee ai?oai?211E?iaioa/a111?io?eoaaiiy
?aie123?aoeeaeeae iooeeie (ca 3 ?iee)2-a noaae?y0003-y noaae?y01 (7,6%)2
(15,4%)Iaoanoace (ca 3 ?iee)2-a noaae?y0003-y noaae?y1 (7,6%)2 (15,4%)3
(25,0%)Nia?oi?noue (ca 3 ?iee)2-a noaae?y0003-y noaae?y1 (8,0%)3
(25,0%)4 (33,3%)Aeaeeaa?i?noue (ca 3 ?iee)92%75%66,7%Aeaeeaa?i?noue (ca
5 ?ie?a)2-a noaae?y84,6%61,5%69,2%3-y noaae?y75,0%46,1%58,3% I?iaaaeai?
ee?i?/i? aeine?aeaeaiiy ?c canoinoaaiiyi ?OAeO oa ?acoeueoaoe e?eoaaiiy
na?ae/aoue, ui iaoiae ia? i?ae niaith ?aaeueio iniiao. ?aoeeaeeaoaaiiy ?
iaoanoacoaaiiy iooeei a iniiai?e a?oi? ia i?ioyc? 3-o ?ie?a i?e II
noaae?? aoee a?aenooi?ie, a i?e III noaae?? a?aenioie ?o aeyaeaiiy aoa
ieae/ei o ii??aiyii? c ia?oith oa ae?oaith eiio?ieueieie a?oiaie oai?eo.
3-o oa 5-oe ??/ia aeaeeaa?i?noue oai?eo iniiaii? a?oie oaeiae ia?aaeuo?
oaeo o oai?eo eiio?ieueieo a?oi ye i?e II, oae ? i?e III noaae?yo
caoai?thaaiiy.

Aeniiaee

1. ?ic?iaeaiee niina ooieoeiiaeueii ?acaeoe ai?oai i?e ?aeo neeaaeeiaiai
aaeaeeo T2-3N0M0, yeee a?oioo?oueny ia caa?aaeaii aa?oiueiai e?ath
ieanoeiee ueoiaeaeiiai o?yua ia aioe a?aaeaiiy ciaioiuei iaaeo?yuieoe,
cia/ii iie?auo ooieoeiiaeuei ?acoeueoaoe eeoaaiiy (aeaeaitheyoey oai?eo
o 85,1% aeiaaeea, aaeiiaeaiiy aieiniai ooieoe a 93,6% aeiaaeea,
caa?aaeaiiy ?icaeeueii ooieoe aeeoaiiy – a 89,4%.

2. Niina o??o?a?/iiai eeoaaiiy ?aeo ai?oai aeicaiey iie?aueoe iieieia/i
?acoeueoaoe (aeai?/ia aeaeeaaiiy noaiiaeoue 89,4%, iyoe?/ia – 72,3%), ui
cia/ii aeua na?aaeio iieacieea a Oe?ai.

3. Aiaec niaeo?ia?ai naae/eoue i?i aenie aieiniooai?thth/ iiaeeeaino
iiaiai niiniao o?o?a/iiai eeoaaiiy ?aeo ai?oai II-III noaae neeaaeeiai
eieaecaoe.

4. I?iaaaeaiiy eiiieaeno aeeoa?aioeeii oiiiiaae?? o ?aiiueiio
ineyiia?aoeeiiio ia?iae (4-6 oeaei) iney ooieoeiiaeueieo ?acaeoee ai?oai
c i?eaiaeo ?aeo cia/ii iie?auo yeni oa?aeoa?enoeee aieino ni?ey
iaaee/ie oa nioeaeueie ?aaaeoaoe oai?eo.

5. Eei/ia canoinoaaiiy iaoiaeo io?aiia?aoeeii oioiaeeiai/ii oa?ai
(IOAeO) ciaioo iaaacia/inoue ?aiio ineyiia?aoeeieo oneeaaeiaiue cia/ii
cieaeo /anoioo ?icaeoeo ?aoeeaeeaa oa iaoanoaca o oai?eo ia ?ae ai?oai
neeaaeeiai eieaecaoe.

I?aeoe/i? ?aeiiaiaeaoe??

1. Aeey o?o?a/ii ?aaaeoaoe aieino o oai?eo ia ?ae ai?oai (T2-3N0M0)
neeaaeeiai eieaecaoe iaeaeueo aeioeeueiei canoinoaaiiy iiaiai niiniao
aaiea?eiaaeoii (iaoaio ? 7176 A aae 30.06.95 ?.).

2. Aia?aoii-i?ia?aiiee eiiieaen aeey aeineaeaeaiiy iiaiiai neaiaeo
aeicaiey i?iaanoe eeueenio yenio ioeieo aeonoe/ieo ia?aiao?a o ii?i
i?e iaoieia.

3. Aeey ?aaaeoaoe ii?ooaii oiiaoi?ii ooieoe ai?oai iney ?acaeoe c
i?eaiaeo ?aeo ?aeiiaiaeooueny i?iaaaeaiiy aeeoa?aioeeii oiiiiaaee/ii
oa?ai.

4. Aeey i?ioeaeoeee ?aoeeaeeaa ? iaoanoac?a i?e eeoaaii ?aeo ai?oai
T2-3N0M0 noaae?? neeaaeeiai eieaecaoe ?aeiiaiaeiaaii canoinoaaiiy
iaoiaeo io?aiia?aoeeii oioiaeeiai/ii oa?ai (IOAeO).

nienie i?aoeue, iioae?eiaaieo ca oaiith aeena?oaoe??

1. Ea?eiaiieanoeea iinea uaaeyueo iia?aoeee ia ai?oaie ii iiaiaeo ?aea
// AEo?iae ooiuo, iiniauo e ai?eiauo aieaciae. – 1995. – ?1. – N.65-71
(Ni?aaao.: Eoea/ Y.A.).

2. Niinia ea/aiey ?aea ai?oaie // Iaoaio ? 7176 A. – 1995 (Ni?aaao.:
Eoea/ Y.A.).

3. Uaaeyuea iaoiaeu oe?o?ae/aneiai ea/aiey aieueiuo ?aeii ai?oaie III
noaaeee neeaaei/iie eieaeecaoeee // AEo?iae ooiuo, iiniauo e ai?eiauo
aieaciae. – 1995. – ?3. – N.7-10.

4. Aeaooeaoiea ?acoeueoaou ooieoeeiiaeueii-uaaeyueo iia?aoeee ii iiaiaeo
?aea ai?oaie III noaaeee n?aaeeiiie eieaeecaoeee // VIII nuacae
ioiea?eiaieiaia Oe?aeiu. – Eeaa. – 1995. – N.368-369.

5. Oioiaeeiaie/aneay oa?aiey i?e ea/aiee ceiea/anoaaiiuo iiooieae.
Ianoiyuaa, i?iaeaiu e ia?niaeoeau a Oe?aeia // Nai?iee
iao/ii-i?aeoe/aneeo noaoae e 200-eaoeth iaeanoiie eeeie/aneie aieueieoeu
ei. E.E.Ia/ieeiaa. – Aeiai?iiao?iane, 1998. – N.282-285. (Ni?aaao. Eoea/
Y.A.).

6. Photodynamic Therapy in ENT-oncology // Proceed. SPIE. – 1995. –
V.2395. – P.179-183. (Ni?aaao. Erwin Loukatch, Galina Latyshevska,
Vasily Trojan, Vladimir Bykov, Igor Obraztsov).

Ia?acoeia ?.A. ?ic?iaea iiaeo niinia?a e?eoaaiiy oai?eo ia ?ae ai?oai?
neeaaeeiai? eieae?caoe??. – ?oeiien.

Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaith eaiaeeaeaoa iaaee/ieo iaoe
ca niaoe?aeuei?noth 14.01.19 – ioi?eiiea?eiaieia?y. – Ee?anueeee
iaoeiai-aeine?aeiee ?inoeooo ioiea?eiaieia?? ?i. i?io. I.N.Eieii?e/aiea
IIC Oe?a?ie, Ee?a, 1998.

Aeena?oaoe?y i?enay/aia ?ic?iaoe? ? ai?iaoaaiith iaoiae?a e?eoaaiiy
oai?eo ia ?ae ai?oai? na?aaeeiii? eieae?caoe?? (o??o?a?/iee ? iaoiae
?io?aiia?aoe?eii? oioiaeeiai?/ii? oa?ai??) aeey i?aeaeuaiiy aoaeoeaiino?
e?eoaaiiy oai?eo ia ceiye?ni? iooeeie ai?oai?.

O ?iaio? i?iaiae?ciaaii ?acoeueoaoe niinoa?aaeaiue o ia??iae e?eoaaiiy
146 iieieia?/ieo oai?eo, c yeeo 50 iaoe??ioai aoei aeeiiaii ??ci?
iiaeeo?eaoe?? aa?oeeaeueieo ?acaeoe?e ai?oai?, 49 – iia?aoe?? ca
iaoiaeii EIAe?I-1, 47 – iiaee niin?a ooieoe?iiaeueii? ?acaeoe?? ai?oai?
– aai?ea?eiaaeoii?y ca iaoiaeii EIAe?I-2. Ii??aiyii ?acoeueoaoe
niinoa?aaeaiue ca oai?eie iniiaii? oa eiio?ieueieo a?oi /a?ac 2 oa 5
?ie?a.

Ia iniia? canoinoaaiiy aia?aoii-i?ia?aiiiai eiiieaeno aeaii ioe?ieo
ii?ooaiue oiiaoi?ii? ooieoe?? o an?o a?oiao niinoa?aaeaiue c iaoith
aecia/aiiy iioeiaeueiiai niiniao ?acaeoe?? ai?oai? o oai?eo ia ?ae
ai?oai? neeaaeeiai? eieae?caoe?? aeey aeinyaiaiiy iiaii? iaaee/ii? oa
nioe?aeueii? ?aaa?e?oaoe??.

Anoaiiaeaii, ui ooieoe?iiaeuei? oa iieieia?/i? ?acoeueoaoe e?au? i?e
canoinoaaii? iiaiai niiniaa aai?ea?eiaaeoii?? (aeai??/ia aeaeeaa?i?noue
– 89,4%, i’yoe??/ia – 72,3%; aeaeaitheyoe?th i?iaaaeaii o 85,1% oai?eo,
oiiaoe?th caa?aaeaii a 93,6%, ?icae?eueii? ooieoe?? oa aeeoaiiy – o
89,4% aeiaaee?a).

Anoaiiaeaii, ui ?io?aiia?aoe?eia oioiaeeiai?/ia oa?ai?y i?aeaeuo?
ye?noue i?ioe?aoeeaeeaiiai e?eoaaiiy o oai?eo ia ?ae ai?oai? neeaaeeiai?
eieae?caoe?? ? ? aeueoa?iaoeaith i?iiaiaaiai iaoiaeo e?eoaaiiy.

Eeth/ia? neiaa: ?ae ai?oai?, aai?ea?eiaaeoii?y, oiiaoi?ia ooieoe?y,
?aaa?e?oaoe?y, oioiaeeiai?/ia oa?ai?y.

Ia?acoeia E.A. ?ac?aaioea iiauo niiniaia ea/aiey aieueiuo ?aeii ai?oaie
neeaaei/iie eieaeecaoeee. – ?oeiienue.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe
ii niaoeeaeueiinoe 14.01.19 – ioi?eiiea?eiaieiaey. – Eeaaneee
iao/ii-enneaaeiaaoaeueneee einoeooo ioiea?eiaieiaee ei. i?io.
A.E.Eieiiee/aiei IC Oe?aeiu, Eeaa, 1998.

Aeenna?oaoeey iinayuaia ?ac?aaioea e ai?iae?iaaieth iaoiaeia ea/aiey
aieueiuo ?aeii ai?oaie n?aaeeiiie eieaeecaoeee (oe?o?ae/aneia ea/aiea e
iaoiae eio?aiia?aoeeiiiie oioiaeeiaie/aneie oa?aiee) aeey iiauoaiey
yooaeoeaiinoe ea/aiey aieueiuo ni ceiea/anoaaiiuie iiaiia?aciaaieyie
ai?oaie.

A ?aaioa i?iaiaeece?iaaiu ?acoeueoaou iaaethaeaiee a ia?eiae ea/aiey 146
iieieiae/aneeo aieueiuo, ec eioi?uo 50 iaoeeaioai auee auiieiaiu
?acee/iua niiniau aa?oeeaeueiuo ?acaeoeee ai?oaie, 49 aieueiui
i?iecaaaeaiu iia?aoeee ii niiniao EIEEI-1 e o 47 i?eiaiai iiaue niinia
ooieoeeiiaeueiie ?acaeoeee ai?oaie – aaieea?eiayeoiiey ii EIEEI-2.
?acoeueoaou iaaethaeaiee ca aieueiuie iniiaiie e eiio?ieueiuo a?oii
i?iaaaeaiu a n?aaiaiee ca 2 aiaea e /a?ac 5 eao.

Ia iniiaaiee i?eiaiaiey aiia?aoii-i?ia?aiiiiai eiiieaena aeaia ioeaiea
noaiaie ia?ooaiey oiiaoi?iie ooieoeee ai anao a?oiiao iaaethaeaiee n
oeaeueth ii?aaeaeaiey iioeiaeueiiai niiniaa ?acaeoeee ai?oaie o aieueiuo
?aeii ai?oaie neeaaei/iie eieaeecaoeee aeey aeinoeaeaiey iieiie
iaaeeoeeineie e nioeeaeueiie ?aaaeeeoaoeee.

Onoaiiaeaii, /oi ooieoeeiiaeueiua e iieieiae/aneea ?acoeueoaou eo/oa i?e
eniieueciaaiee iiaiai niiniaa aaieea?eiayeoiiee (2-o eaoiyy
auaeeaaaiinoue ninoaaeea 89,4%, 5-e eaoiyy – 72,3%; aeaeaitheyoeeth
i?iaaaeaii o 85,1% aieueiuo, oiiaoeey nio?aiaia a 93,6%,
?acaeaeeoaeueiay ooieoeey e aeuoaiea – a 89,4% neo/aaa).

Onoaiiaeaii, /oi eio?aiia?aoeeiiiay oioiaeeiaie/aneay oa?aiey iiauoaao
ea/anoai i?ioeai?aoeeaeeaiiai ea/aiey o aieueiuo ?aeii ai?oaie
neeaaei/iie eieaeecaoeee e yaeyaony aeueoa?iaoeaie eo/aaiai iaoiaea
ea/aiey.

Inouanoaeaii aiaae?aiea a i?aeoeeo iiaiai niiniaa ea/aiey ?aea ai?oaie.

Eeth/aaua neiaa: ?ae ai?oaie, aaieea?eiayeoiiey, oiiaoi?iay ooieoeey,
?aaaeeeoaoeey, oioiaeeiaie/aneay oa?aiey.

Obraztsov I.G. “The evoluation of methods of treatment of laryngeal
cancer patients with localization in the vocal cords area”. –
Manuscript.

The dissertation is presented for the Scientific degree of Candidate of
Sciences (Medicine) in speciality 14.01.19. — otorhynolaryngology. —
Kolomijchenko Research Institute of otorhynolaryngology, Kiev 1998.
Specialized Academic Council D 26.622.01.

Thesis is about seeking an optimal method of resection of laryngeal
cancers to have an almost full social and medical rehabilitation. To
measure the rate of malfonation in all patient groups special
hardware-software complex was used with idea of finding optimal
laryngeal resection method in spite of full social and medical
rehabilitation. Assured, that the new hemilaryngectomy method is better
measured by functional and oncological results (2 year term survival
rate is 89,4%; 5-year term survival — 72,3%; decanulation — 85,1% of
patients, fonation present in 89,4% of cases).

The Intraoperative Photodynamic Therapy enchances the quality of
antirecidive treatment in vocal and vestibular cords cancer patients and
is an alternative to X-ray therapy.

The new method of laryngeal cancers treatment had been introduced into
the practice.

Keywords: laryngeal cancer, hemilaryngectomy, fonation function,
rehabilitation, photodynamic therapy, PHT.

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