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Протиаритмічна ефективність медикаментозної і комбінованої терапії при порушеннях ритму серця у хворих на хронічну ішемічну хворобу серця та її обгрун

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OA?E?ANUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

ia i?aaao ?oeiieno

EAOIAOC TH??E ?AAIIAE*

OAeE: 616.12008.46+616.124.2:/615.225.2:615.355

I?IOEA?EOI?*IA AOAEOEAI?NOUe IAAeEEAIAIOICII? ? EIIA?IIAAII? OA?AI?? I?E
II?OOAIIssO ?EOIO NA?Oess O OAI?EO IA O?II?*IO ?OAI?*IO OAI?IAO NA?Oess
OA ?? IAA?OIOOAAIIss

14.01.11-Ea?ae?ieia?y.

A a o i ? a o a ? a o

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a-1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Oa?e?anuee

iio aea?aeaaiiio iaaee/iiio oi?aa?neoao? IIC OE?A?IE.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani? Ieueaa Ieeiea?aia
Eiaaeueiaa, Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, caa?aeoaa/
eaoaae?e i?iiaaeaaoeee aioo??oi?o oai?ia ?1.

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani? Aieeia Aieiaeeie?
?aaiiae/, ?inoeooo oa?ai?? AII Oe?a?ie, i. Oa?e?a, caa?aeoaa/ a?aeae?eo
aoa?ineea?ico oa eiai oneeaaeiaiue;

eaiaeeaeao iaaee/ieo iaoe, aeioeaio Oonoaaeue Ieeiea Oaaei?iae/,
Oa?e?anueeee ?inoeooo oaeineiiaeaiiy e?ea??a, caa?aeoaa/ eaoaae?e
ea?ae?ieia?? ? ooieoe?iiaeueii? ae?aaiinoeee.

I?ia?aeia onoaiiaa: Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo
ea?ae?ieia?? ?i. aeaae.I.Ae.No?aaeanea, IIC Oe?a?ie, i.Ee?a, a?aeae?e
aoa?ineea?ico oa o?ii?/ii? ?oai?/ii? oai?iae na?oey.

Caoeno a?aeaoaeaoueny “ 10 ” /a?aiy 1999 ?ieo i 1330 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.600.04 i?e Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca aae?anith: 310022, i. Oa?e?a,
i?. Eai?ia 4, o.40-26-27.

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (i. Oa?e?a, i?. Eai?ia 4).

Aaoi?aoa?ao ?ic?neaiee 27 ea?oiy 1999 ?ieo.

A/aiee nae?aoa? niaoe?ae?ciaaii?

a/aii? ?aaee, eaiaeeaeao iaaee/ieo iaoe,

aeioeaio
IA*A?AIEI E.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

AEOOAEUeI?NOUe OAIE. ?oai?/ia oai?iaa na?oey, ii aeaiei AIC, ?
“ai?aeai??th” XX noi??//y. I?aai?caoe?y ai?ioueae c na?oeaai-noaeeiieie
caoai?thaaiiyie, a oiio /ene? c ?ON, ia? aaeeeo cia/ei?noue ?
?aae?co?oueny /eneaiieie iaoeiaeie aeine?aeaeaiiyie (Iaea E.O.,
1993-1998 ?.?.; *acia ?.?., 1982-1998 ?.?.; Nhung E.K., 1983).

Ii?ooaiiy ?eoio na?oey ? iaei??th c aeooaeueieo i?iaeai no/anii?
ea?ae?ieia?? ? iathoue iaaecae/aeii aaeeea ye oai?aoe/ia, oae ?
i?aeoe/ia cia/aiiy.

A?eoi?? cono??/athoueny i?aeoe/ii i?e an?o na?oeaai-noaeeiieo
caoai?thaaiiyo, aea iniaeeai /anoi i?e ?ON (Aeiueoeei A. E., 1989-1997
?.?.; Niaoi?a I.N., 1986-1990 ?.?.; Lown B., 1980).

Oae, o aino?iio ia??iae? ?ioa?eoa i?iea?aeo ii?ooaiiy ?eoio na?oey ii
aeaiei ??cieo aaoi??a niinoa??aathoueny a 95-100%, i?e O?ON a 50-70%
aeiaaee?a (Aia?ia A.I., 1995; Eiaaeueiaa I.I., 1998; Weiner D., 1988).

Aeooaeuei?noue aea/aiiy a?eoi?e iiynith?oueny ia o?eueee ?oiueith
/anoioith, aea ? ?ioeie ianoaaeiaie, a naia:

1. A ?yae? aeiaaee?a, iniaeeai o oai?eo ?ON, a?eoi?? i?aaenoaaeythoue
aaciina?aaeith caa?ico aeeooth (Caiioa?a ?.I., Eiceinueeee E.A.,
Ea?eiiaa ?.A., 1990; Ca?aiaa ?.Ae., *eae A.Ae., *eae I.?., 1988; Julian
D., 1988).

2. I?e aino?iio ?ioa?eo? i?iea?aeo ii?ooaiiy ?eoio na?oey iiaeooue
ni?eyoe ?iciianthaeaeaiith ciie iae?ico i?iea?aea ? ?icaeoeo
e?aioeoii/eiai? iaaeinoaoiino? (Iaaeinooi I.A., Ne?e?i I.E., 1991;
ssiooeaa?/on C.?., A?aae?e?n TH.TH., Eoeioaa?/thoa I.I., Caaaea I.A.,
1994; Puech P., 1985).

3. I?e O?ON a?eoi?? iia??oothoue ia?aa?a, i?iaiic ? aoaeoeai?noue
e?eoaaiiy (Aiea?ey E.I., 1989; Eooaeianeee I.N., 1992; Bigger J.T.,
1988).

4. Ii?ooaiiy ?eoio na?oey ?noioii iia??oothoue aaiiaeeiai?eo ?
ni?eythoue ?icaeoeo na?oeaai? ? noaeeiii? iaaeinoaoiino?. Oae,
aeno?anenoie?y oeio a?aai?i?? cieaeo? na?oeaaee aeeeae ia 15-20%,
ia?aao?iiy ia?aaena?aeue ia 20-30%, ia?ieneciaeueia oao?ea?ae?y ia
50-80% (I?ie?i ?.A., 1994; Iaooiaa I.I., 1985; Gallay P., 1985).

C i’yoe a?aeiieo a?oi a?eoiiaaiieo oaeoi??a (iaoaaie?/i?, aiaoii?/i?,
aaiiaeeiai?/i?, aaoiiiii? ? yo?iaaii?) iaea?eueo ?aii?ie c ieo ?
ii?ooaiiy iaoaaie?cio ? iae?iaoii?aeueii? ?aaoeyoe?? aiiainoaco (Aiiniaa
E.I., 1995; A?ce? A.Ae., 1989; A?eoethe I.?., 1989; Aaiaeaea ?.I., 1989;
Robertson S.W., 1989), ui ia? aaaeeeaa cia/aiiy aeey i?io?eaeoeee ?
oa?ai?? a?eoi?e.

Aeaeaei iaae??oaiith ? oaeiae i?iaeaia ?aoe?iiaeueii?, iaoiaaiaoe/ii? ?
aeeoa?aioe?eiaaii? oa?ai?? a?eoi?e, aieeao i?ioea?eoi?/ieo i?aia?ao?a, a
oaeiae iaiaaeeeaiaioicieo cania?a e?eoaaiiy ? ?oi?o eiia?iaoe?e ia
iaoaaie?/i?, iae?iaoii?aeuei? ? aaiiaeeiai?/i? oaeoi?e iaoiaaiaco
oeueiai oneeaaeiaiiy i?e o?ii?/i?e ?oai?/i?e oai?ia? na?oey (Iaco? I.I.,
1988; Iaoaeeoey A.?., 1987; Podrid P.J., 1992), a oaeiae i?ioea?eoi?/ia
aoaeoeai?noue iiai? a?oie e?ea?nueeeo cania?a – ?ia?a?oi??a AIO ?
aioaaii?no?a ?aoeaioi??a aia?ioaiceia-II (Aieeia A.?., 1998;
Ieuea?inueea E.?., 1993; Bielem E.C., Fagard R.H., 1992).

A?aoiaoth/e aeua aeeeaaeaia, iaie aoa aaeeoee iaoiaaiaoe/iee i?aeo?ae
aei aea/aiiy oe??? i?iaeaie.

Ca‘ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie.

Iao? aeine?aeaeaiiy aeeiiai? o a?aeiia?aeiino? c iaoeiaei ieaiii IIC
Oe?a?ie, eaoaae?e i?iiaaeaaoeee aioo??oi?o oai?ia ? 1 Oa?e?anueeiai
Aea?aeaaiiai iaaee/iiai Oi?aa?neoaoo ii i?iaeai? “I?io?eaeoeea ?
e?eoaaiiy na?oeaai-noaeeiieo caoai?thaaiue” (? aea?ae. ?a?no?aoe??
78082497).

IAOA ? CAAeA*? AeINE?AeAEAIIss

Iniiaiith iaoith ?iaioe ? aaeineiiaeaiiy ae?aaiinoeee oa e?eoaaiiy
ii?ooaiue ?eoio o oai?eo ia o?ii?/io ?oai?/io oai?iao na?oey. Aeey
aeinyaiaiiy oe??? iaoe aoee iinoaaeai? ianooii? caaea/?:

1. Aea/eoe iniaeeaino? ia?aa?ao ? i?iaiinoe/ia cia/aiiy ii?ooaiue ?eoio
i?e O?ON.

2. Aecia/eoe ?ieue iaoaaie?/ieo ? iae?iaoii?aeueieo ii?ooaiue, ?oi?o
aca?iica’yce?a ? aca?iia?aeiinei a iaoiaaiac? a?eoi?e, noai
neiiaoiaae?aiaeiai?, ?ai?i-aia?ioaicei-aeueaeinoa?iiiai?,
i?inoaaeaiaeeiiai? nenoai, IIE ? AIN, ai?no a?eueieo aee?ieo eeneio,
eae?th ? iao??th a ieaci? ? a?eo?ioeeoao, a oaeiae ooieoe??
iaaeie?iee?a, oeeee?/ieo ioeeaioeae?a (oeAIO, oeAIO), EEN.

3. Aecia/eoe cia/aiiy ii?ooaiue oeaio?aeueii?, ia?eoa?e/ii?
aaiiaeeiai?ee ? aioo??na?oeaai? e?iaoeee a iaoiaaiac? a?eoi?e.

4. I?iaanoe ii??aiyeueia aea/aiiy i?ioea?eoi?/ieo i?aia?ao?a, a oaeiae
?o eiia?iaoe?? c aioeieneaeaioaie ? iaiaaeeeaiaioicieie caniaaie
e?eoaaiiy (AOOIE) c iaoith ?ic?iaeoe oaeoeeo aeeoa?aioe?eiaaiiai
canoinoaaiiy ? iai?oeoe iiaeeea?noue aecia/aiiy cania?a aeai?o i?e
a?eoi?yo ?c o?aooaaiiyi iaoaaie?/ieo, iae?iaoii?aeueieo ?
aaiiaeeiai?/ieo ii?ooaiue.

5. Iaa?oiooaaoe i?ioea?eoi?/io aoaeoeai?noue iiaiai eeano e?ea?nueeeo
cania?a – ?ia?a?oi??a AIO (?ai?oaea) ? aioaaii?no?a ?aoeaioi??a
aia?ioaiceia-II (eicaa?a).

6.Aecia/eoe ?ieue ? i?noea iaaeeeaiaioicii? ? eiia?iiaaii? oa?ai??
ii?ooaiue ?eoio na?oey o eiiieaeniiio e?eoaaii? O?ON ?c ai?iaaaeaeaiiyi
?? iniiaieo i?eioeei?a a ee?ie/io i?aeoeeo.

IAOEIAA IIAECIA

I?iaaaeai? aeine?aeaeaiiy aeicaieeee:

1. C aeei?enoaiiyi no/anieo cania?a aeine?aeaeaiiy aea/eoe iniaeeaino?
ia?aa?ao, ae?aaiinoe/io ? i?iaiinoe/io cia/ei?noue ii?ooaiue ?eoio
na?oey o oai?eo O?ON.

2. Aecia/eoe cia/aiiy iaoaaie?/ieo ? iae?iaoii?aeueieo oaeoi??a, ?oi?o
aca?iica’yce?a (eaoaoieai?ie, AAEE, i?iaeoeoe IIE, noai AIN,
yeaeo?ie?oe, EEN, ?AAN, EEN, oeAIO, oeAIO), a oaeiae aaiiaeeiai?/ieo
ii?ooaiue a iaoiaaiac? a?eoi?e i?e O?ON.

3. Iieacaoe ae?aaiinoe/io cia/ei?noue aecia/aiiy aeuacacia/aieo
aenieiaeoeaieo niieo/aiue ? ia?aiao??a aaiiaeeiai?ee aeey anoaiiaeaiiy
aaaeeino? ? i?iaiico ii?ooaiue ?eoio na?oey o oai?eo O?ON.

4. Ia iiaiio iaoiaee/iiio ??ai? aecia/eoe i?ioea?eoi?/io aoaeoeai?noue,
iaoaaie?/iee, iae?iaoii?aeueiee ? aaiiaeeiai?/iee aieea aioea?eoi?/ieo
cania?a (o?iiio?ia, aeeai?i?ia) ? ?oi?o eiia?iaoe?e c aioeieneaeaioaie
(o?iiio?i+aeueoa-oieioa?ie) ? iaiaaeeeaiaioicieie caniaaie e?eoaaiiy
(aeeai?i?i+ AOOIE).

5. Ia no/aniiio ??ai? aea/eoe i?ioea?eoi?/io aoaeoeai?noue iiaiai eeano
e?ea?nueeeo cania?a – ?ia?a?oi??a AIO (?ai?oaea) ? aioaaii?no?a
?aoeaioi??a aia?ioaiceia-II (eicaa?a).

I?AEOE*IA CIA*AIIss ?IAIOE

I?aeoe/ia cia/ei?noue ?iaioe iieyaa? a oiio, ui a ?acoeueoao?
i?iaaaeaieo aeine?aeaeaiue aeiaaaeai?:

1. Iaiao?aei?noue, aeey aecia/aiiy aaaeeino? ? i?iaiico a?eoi?e i?e
O?ON, aeine?aeaeaiiy iaoaaie?/ieo, iae?iaoii?aeueieo ? aaiiaeeiai?/ieo
aniaeo?a iaoiaaiaco: eaoaoieai?i?a, AIN, AAEE, i?iaeoeo?a IIE,
yeaeo?ie?o?a, EEN, ei?o?ciea, IA, ?ai?ia, aia?ioaiceia, aeueaeinoa?iia,
oeAIO, oeAIO.

2. Oa?aiaaoe/ia, iaoaaie?/ia, iae?iaoii?aeueia ? aaiiaeeiai?/ia
aoaeoeai?noue IAI ? ?o eiia?iaoe?e c aioeieneaeaioaie ?
iaiaaeeeaiaioicieie caniaaie e?eoaaiiy (o?iiio?i, aeeai?i?i, ?ai?oae,
eicaa?, o?iiio?i+aeueoa-oieioa?ie, aeeai?i?i+AOOIE).

3. Aeioe?euei?noue eiio?ieth ca aeuacacia/aieie oaeoi?aie iaoiaaiaco
a?eoi?e i?e i?iaaaeaii? e?eoaaiiy.

4. Aea?? ? iine?aeiai?noue e?eoaaeueieo caoiae?a, iniiai? i?eioeeie
aeeoa?aioe?eiaaii? iaoiaaiaoe/ii? oa?ai?? i?e ii?ooaiiyo ?eoio na?oey o
oai?eo O?ON.

?acoeueoaoe aeine?aeaeaiiy aeei?enoiaothoueny a ?iaio? ?inoeoooo Oa?ai??
AII Oe?a?ie, aei?iaeii? ee?i?/ii? e?ea?i? ?2 (ea?ae?ieia?/iiio oa
?ioa?eoiiio a?aeae?eaiiyo), a 11-e i?nuee?e e?ea?i? OII
*a?aiiicaaiaenueeiai ?aeiio i. Oa?eiaa, a iaa/aeueii-iaaeaaia?/iiio
i?ioean? ia oa?aiaaoe/ieo eaoaae?ao Oa?e?anueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo oa ?inoeoooo oaeineiiaeaiiy e?ea??a.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy aeicaiey? i?aeaeueoe
aoaeoeai?noue ae?aaiinoeee ? e?eoaaiiy, noai o aeinoaoiuei aaaeeiai
eiio?iaaioo oai?eo, ciaioeoe o?eaae?noue ia?aaoaaiiy a noaoe?iia??,
i?aeaeueoe ??aaiue ciaiue nooaeaio?a ? e?ea??a.

Ii oai? aeena?oaoe?? aeaeaiee o/aiai-iaoiaee/iee iin?aiee aeey
nooaeaio?a ? e?ea??a “Ia?ooaiea ?eoia na?aeoea. Ea/aiea, i?ioeeaeoeea e
iaioeiaeiay iiiiuue”, i.Oa?e?a, 1996 ?., 54n.

INIAENOEE AIANIE CAeIAOAA*A

Naiino?eii cae?enithaaa i?aea?? oa ianoaaeaiiy oaiaoe/ieo oai?eo.
Iniaenoi i?iaiaeea: a?io?i?/i?, aeaeo?io?c?ieia?/i? ? ?ino?oiaioaeuei?
iaoiaee aeine?aeaeaiiy o an?o 157 oai?eo O?ON; eiio?ieue ca
aoaeoeai?noth e?eoaaiiy; iiaio noaoenoe/io ia?iaeo iaoa??aeo; aiae?c
io?eiaieo ?acoeueoao?a; iaienaiiy an?o ?icae?e?a, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e; ai?iaaaeaeaiiy ? ioae?eaoe??; ioi?ieaiiy aeena?oaoe?eii?
?iaioe.

AI?IAAOe?ss ?ACOEUeOAO?A AeINE?AeAEAIIss

Iaoa??aee aeena?oaoe?? aoee aeieeaaeai? ? iaaiai?ai? ia ia’?aeiaiiio
can?aeaii? eaoaae? aioo??oi?o oai?ia ?1 ? aioo??oi?o oai?ia, EOE ? NI
2-ai iaaee/iiai oaeoeueoaoo Oa?e?anueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo.

Iniiai? iieiaeaiiy ?iaioe iia?aeiieai? ia can?aeaii? OIIO (1996-1998
?.?.), 2-e i?aeia?iaei?e eiioa?aioe?? ii cae?cie/i?e iaaeeoeei?
(1996?.), i?aeia?iaeiiio neiiic?oio c a?eoi?e a ?c?a?e? (1997?.),
iaoeiaeo eiioa?aioe?yo oi?aa?neoaoo.

IOAE?EAOe??

Ca oaiith aeena?oaoe?? iioae?eiaaii 10 ?ia?o, c ieo 4 o i?ia?aeieo
oaoiaeo aeaeaiiyo, 6-oue noaoae oa 4-e oace aeiiia?aeae.

NO?OEOO?A OA IANssA AeENA?OAOe??

Aeena?oaoe?y aeeeaaeaia ia 210 noi??ieao iaoeiiieno ? neeaaea?oueny c
anooio, nieneo nei?i/aiue, iaeyaeo e?oa?aoo?e (1-a aeaaa), cania?a
aeine?aeaeaiiy (2-a aeaaa), ee?ie/ii? oa?aeoa?enoeee oai?eo (3-y aeaaa),
?acoeueoao?a aeine?aeaeaiiy (4, 5, 6 aeaae), iaaiai?aiiy ? caaaeueiiai
iai??eoaaiiy aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e ? nieneo e?oa?aoo?e.
?iaioa ?ethno?iaaia 17 iaethieaie ? 30 oaaeeoeyie, (ui neeaaea? 47
noi?.). Nienie e?oa?aoo?e i?noeoue 392 a?o/eciyi? ?iaioe oa e?a?i NIAe ?
155 ?ia?o ?iicaiieo aaoi??a, (ui neeaaea? 60 noi?.).

CI?NO ?IAIOE

OA?AEOA?ENOEEA OAI?EO ? IAOIAeE

A oiiaao ea?ae?eia?/iiai ? ?ioa?eoiiai a?aeae?eaiue i?iaaaeaia
ianoaaeaiiy 157 oai?eo o?ii?/iith ?oai?/iith oai?iaith na?oey, c ieo 108
oai?eo ?c ii?ooaiiyie ? 49 aac ii?ooaiiy ?eoio na?oey.

Ae?aaiic O?ON a?oiooaaany ia oa?aeoa?ieo nea?aao oai?eo, ee?ie/ieo
aeaieo, aeoeaiino? oa?iaio?a e?ia? (EOE, ?? “IA” o?aeoe??, EAeA, ANO,
AEO), aeeiai?oe? aeaeo?i-, ?ai- ? aoiea?ae?ia?ao?/ieo iieaciee?a.

O a?oi? oai?eo ?c ii?ooaiiyie ?eoio na?oey ia?aaaaeaee /ieia?ee (55,6%),
oai?? o a?oe? 45-74 ?ie?a, ?c a?ia?oii?/iith oai?iaith na?oey (85%),
noaa?eueiith noaiiea?ae??th II ? III ooieoe?iiaeueiiai eean?a (24,1% ?
36,1%), iaaeinoaoi?noth e?iaiia?ao IIA noaae?? (72,2%).

Ii aeaiei ea?ae?iiii?oi?iiai ? aeaeo?iea?ae?ia?ao?/iiai ianoaaeaiiy
a?eoi?? aoee aecia/ai? o 108 ?c 157 oai?eo O?ON (68,8%), /ano?oa ca
ae?oa? cono??/aeenue ieaioeeaa a?eoi?y (36,1%), oeoii/eiaa (26%) ?
iaaeoeoii/eiaa aeno?anenoie?y (19,4%) (iae. 1).

Iae. 1. *anoioa ??cieo a?eoi?e a ianoaaeai?e a?oi? oai?eo.

· Aecia/aiiy eaoaoieai?i?a a na/? i?iaiaeeeiny ii iaoiaeo A. I. Aa?o
(1962), ui ? iiaeeo?eaoe??th oeoi?anoeaioiiai caniao A. I. Ineinueei?
(1957) aeey aeine?aeaeaiiy /enoeo ?ic/ei?a ? oeaiei.

· Aecia/aiiy a?eueieo aee?ieo eeneio a ne?iaaooe? e?ia? ii iaoiaeo V.P.
Dole (1956).

· Aeey niinoa?aaeaiiy IIE aecia/aee aoeaoeea?ae?iia?aeene a aaoa- ?
i?aaaoa-e?iii?ioa?aeao, ia?aeeniee a?ae?ie?c a?eo?ioeeo?a, aeoeai?noue
eaoaeace e?ia?, iaeiiiaee ae?aeueaeaa?ae. Caaania/ai?noue
aioeieneaeaioaie aoea ioe?iaia ca aeiiiiiaith e?iaaaeueiiai oanoo, ui
iieaco? iane/aiiy neeciai? yceea anei?a?iiaith eeneioith
(Aine?anainueeee I.I. c ni?aaaoi?aie, 1972; Jager F., 1968; Iooe?i I.,
1963; Aaienia?/ A.?. oa ?aeaeuenii E.?., 1973).

· Aecia/aiiy eae?th ? iao??th a ieaci? oa a?eo?ioeeoao i?iaiaeeeiny
iaoiaeii iieoiaiaai? oioiiao???. Eeneioii-eoaeiee noai aea/aee ia
i?eeaae? “I?e?i-Ano?oi” aeaonueei? o??ie “?aae?iiao?”.

· Aeey aecia/aiiy ??aiy i?inoaaeaiaeei?a A, E, F1a ? F2a aoee
aeei?enoai? noaiaea?oi? iaai?e (KIT).

· OeAIO, oeAIO, ?ai?i, aia?ioaicei-I, aeueaeinoa?ii, ei?o?cie aecia/aee
c aeei?enoaiiyi eiia?oe?eieo noaaea?oieo oano-iaai??a.

· Aecia/aiiy eaee?e?a?ia ? eaee?e?a?iiaaia a ne?iaaooe? e?ia?
i?iaiaeeeiny ii iaoiaeo O. N. Ianoeii? ? A. A. E?einueei? (1974).

· Aoiea?ae?ia?ao?/ia aeine?aeaeaiiy i?iaiaeeeiny ia aia?ao? “Neaeae
0.1”.

· Oao?aiiey?ia a?oaeia ?aia?ao?y i?iaiaeeeany ca aeiiiiiaith i?eno?ith
?IA-2-02 ca caaaeueiii?eeiyoith iaoiaeeeith.

Noaoenoe/ia ia?iaea ?acoeueoao?a aeine?aeaeaiiy i?iaiaeeeanue ca
cae/aeiei niiniaii aa??aoe?eii? noaoenoeee (I. Aaee?, 1964; Ae.
Naiaoe??a, 1968) ia aeaeo?iiii-ia/enethaaeuei?e iaoei? oeio IBM c
aeei?enoaiiyi e?eoa??th t, eiao?oe??ioo ei?aeyoe??.

?ACOEUeOAOE AeINE?AeAEAIIss OA ?O AIAE?C

Aeine?aeaeaiiy noaio neiiaoiaae?aiaeiai? nenoaie. A caaaeuei?e a?oi?
oai?eo c a?eoi?yie (91) aoei anoaiiaeaii cia/ia ca?eueoaiiy aeiaiai?
aene?aoe?? a?eueieo o?aeoe?e ye aae?aiae?io (70.3±3.3 iiieue/aeiao i?e
ii?i? 48.0±2.1 iiieue/aeiao, ?

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