I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

IAOe?IIAEUeIEE IAAeE*IEE OI?AA?NEOAO

?i. I.I.AIAIIIEUeOess

EAI?INUeEEE A’ss*ANEAA AIEIAeEIE?IAE*

OAeE 618.3-008.6-037-084-08(616-071-054.001.5)

I?IAIICOAAIIss, I?IO?EAEOEEA

OA E?EOAAIIss I?CI?O AANOIC?A (EE?I?EI-EAAI?AOI?IA OA

AIO?III-AAIAOE*IA AeINE?AeAEAIIss)

14.01.01. aeooa?noai oa a?iaeieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai

nooiaiy aeieoi?a iaaee/ieo iaoe

EE?A – 1999

Aeena?oaoe?y ? ?oeiienii.

?iaioo aeeiiaii a Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao? ?i.
I.I.Aiaiiieueoey IIC Oe?a?ie oa o A?iieoeueeiio iaaee/iiio oi?aa?neoao?
?i. I.?.Ie?iaiaa IIC Oe?a?ie

Iaoeiaee eiinoeueoaio:

aeieoi? iaaee/ieo iaoe, i?ioani? Aaioee?anueeee Ai?en Ieoaeeiae/,
Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey IIC Oe?a?ie,
caa?aeoth/ee eaoaae?ith aeooa?noaa oa a?iaeieia?? ?1

Io?oe?ei? iiiiaioe:

— aeieoi? iaaee/ieo iaoe, i?ioani?, aeaaeai?e IAI Oe?a?ie A?euaiei
Aaeaioei ?aaiiae/, Oa?e?anueeee iaaee/iee oi?aa?neoao IIC Oe?a?ie (i.
Oa?e?a) caa?aeoth/ee eaoaae?ith aeooa?noaa oa a?iaeieia??

— aeieoi? iaaee/ieo iaoe, i?ioani? Ia?e?i Eaii?ae Ai?eniae/,
Euea?anueeee iaaee/iee oi?aa?neoao IIC Oe?a?ie, caa?aeoth/ee eaoaae?ith
aeooa?noaa oa a?iaeieia??

— aeieoi? iaaee/ieo iaoe, i?ioani? Ooiaiiaa Ea?ena ?aaai?aia, ?inoeooo
iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie, caa?aeoth/a
a?aeae?eii i?io?eaeoeee oa e?eoaaiiy ai?eii-caiaeueieo caoai?thaaiue a
aeooa?noa?

I?ia?aeia onoaiiaa: Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe
?i. I.E.Ooieea IIC Oe?a?ie, eaoaae?a aeooa?noaa, a?iaeieia?? oa
ia?eiaoieia??

Caoeno a?aeaoaeaoueny 2 aa?aniy 1999 ?ieo i 1330 aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee ii caoenoo aeena?oaoe?e ia caeiaoooy
iaoeiaiai nooiaiy aeieoi?a iaoe ca niaoe?aeueiinoyie “O??o?a?y”,
“Noiiaoieia?y”, “Aeooa?noai oa a?iaeieia?y”, “Aeeoy/a o??o?a?y” (Ae
26.003.03) i?e Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao? ?i.
I.I.Aiaiiieueoey IIC Oe?a?ie (252030, i. Ee?a, aoeueaa? Oaa/aiea, 17)

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Iaoe?iiaeueiiai
iaaee/iiai oi?aa?neoaoo ?i. I.I.Aiaiiieueoey IIC Oe?a?ie (252057, i.
Ee?a, aoe. Ciieia?/ia, 3)

Aaoi?aoa?ao ?ic?neaiee 21 eeiiy 1999 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

e.i.i., aeioeaio ss.I.A?oianueeee

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue aeine?aeaeaiiy

Na?aae iaeaaaeeea?oeo i?iaeai aeooa?noaa i?ci? aanoice caeiathoue iaeia
c i?ia?aeieo i?noeue. Aeooaeuei?noue i?iaeaie aecia/a?oueny cia/iith
/anoioith oe??? iaoieia?? (13-15%) ? oyaeeeie oneeaaeiaiiyie, ye?
iiaeooue ?icaeiooeny o aaa?oieo i?e ianai?/ani?e ae?aaiinoeoe? oa
iaaaeaeaaoii canoiniaaiiio e?eoaaii? (A.E.Noaiaie?anueea, 1994; E.N.
Neaei?iaa, 1996).

I?e/eie aeieeiaiiy i?ciueiai aanoico aei oaia??oiueiai /ano inoaoi/ii ia
c’yniaai?, iaeiae ca aeaieie a?o/eciyii? ? ca?oa?aeii? e?oa?aoo?e iiaeia
i?eionoeoe, ui iniiaio ?ieue o ?icaeoeo oeueiai oneeaaeiaiiy
a?ae?a?athoue ii?ooaiiy, ye? aeieeathoue o no?ieao noaeei i?e
i?iieeiaii? aioeaai?a ieiaea /a?ac i?e?ieaiaee ieaoeaioe a e?iaiia?a
iaoa?? (E.A.Ai?ii?i c ni?aaao., 1988; A.I.Naaaeueaaa, 1998 ).

Oai??y ii?ooaiue a i?e?ioee?eoeyoi?iiio ?one? oaoi-ieaoeaioa?iiai
eiiieaeno i?e i?ci?o aanoicao i?aeoaa?aeaeaia /anii oa ?acoeueoaoaie
cai?iiiiiaaiiai aaaaoueia a/aieie e?eoaaiiy, yea iie?auo?
i?e?ioee?eoeyoe?th (A.I.Aaioee?anueeee, 1994; A.O.Aaiaeee, 1994;
A.I.Aanaae?i, 1990; A.I.Caii?iaeai c ni?aaao., 1994). Ii?yae c oeei,
aeaye? aaoi?e na?aae i?e/ei aeieeiaiiy i?ci?o aanoic?a, a?aecia/athoue
aaaeeeao ?ieue niaaeeiaeo oaeoi??a ?, cie?aia, aaiaoe/ii? noeeueiino?
aei iaoieia??, ui aea/a?oueny. Iiiaeeiie? ioae?eaoe?? (A.Ae.Aa?aeuoaa,
1990; A.I.Ae?aiiee, A.I.Aeecee, 1990) i?aeoaa?aeaeothoue oeth a?iioaco,
aea ia aeicaieythoue neeanoe oe?e?nii? oyae i?i aeaio i?iaeaio.

Ieoaiiy i?iaiicoaaiiy ? i?io?eaeoeee aoaeue-yei? iaoieia??, ? iniaeeai
aeooa?nueei?, iaaecae/aeii aeooaeuei?, aiane?aeie iiaeeeaino? aeieeiaiiy
na?eicieo oneeaaeiaiue, iia’ycaieo c aaa?oiith ? iiaiia?iaeaeaiei
(A.O.Ieoaeeaiei, I.A.AEo/aiei, 1989).

Iaoaiaoe/i? iaoiaee i?iaiicoaaiiy aeicaieythoue ooi/ithaaoe ae?aaiic ?
i?iaiic, a?aoiaoth/e aaeeeo e?euee?noue ?iiae? iaei cia/oueo iciae ? c
iaaenieith a??ia?aei?noth (A.E.A?euaiei, 1994). Oiio i?iaiicoaaiiy a
eiiieaen? c aeei?enoaiiyi eiinoaooth/eo (niiaoioei, iniaeeaino? aoaeiae
i?e?ioee?eoeyoi?iiai ?onea, ai?iiiaeuei? oa a?io?i?/i? ia?aiao?e) ?
i?iaiinoe/ieo (aaiaoe/i? ia?ea?e e?ia?) iciae ? a?eueo aoaeoeaiei ?
iaiao?aeiei o iianyeaeaii?e ?iaio? aeooa??a-a?iaeieia?a.

O ca’yceo c oeei, a iiia?aaeaeaii? i?ci?o aanoic?a oa e?eoaaii? ?o ia
?aii?o aoaiao a?eueo?noue aaoi??a aeae?eythoue aeaa iniiaieo iiiaioe:
aea/aiiy a?oi aenieiai ?eceeo ?icaeoeo oe??? iaoieia?? oa nai?/ania
i?io?eaeoe/ia e?eoaaiiy aaa?oieo a?oi aenieiai ?eceeo (E.A.Aeeaeaiei,
1987; I.*.Aaoeaeiaa, 1990; A.A.Ianaiei, 1996). Oe? aaaeeea? iieiaeaiiy
iaie a?aoiaai? i?e i?iaiicoaaii? oa aeeiiaii? ee?i?/ieo aeine?aeaeaiue.
A ianooiia ?o oai?aoe/ia iaa?oiooaaiiy a?aoiaoaaei oaeiae oa, ui,
iiaeeeai, iniiaiith iaoiao?ieia?/iith i?e/eiith aeieeiaiiy i?ci?o
aanoic?a (iniaeeai iaa?yeiai-iao?ioe/ieo oi?i), ? aooi?ioii? i?ioeane oa
ii?ooaiiy ia ??ai? i?e?ioee?eoeyoi?iiai ?onea a nenoai?
iaoe-ieaoeaioa-ie?ae (I.A.AEo/aiei, 1989; E.N. Neaei?iaa, 1996).

Iniiaiee iai?yiie iaoi? ?iaioe aaco?oueny ia oya? aaaaoueio no/anieo
aaoi??a i?i oa, ui aieiaiith ciiith o?aaeaiiy ? noaeeiii-o?iiaioeeoa?ia
? i?e?ioee?eoeyoi?ia eaiea ieaoeaioe, ie?ie, ia/?iee, iiceo. Oiio
a?eueo?noue aaoi??a (A.I.Aaioeeianeee, 1984; I.A.?aieia, 1988;
A.E.Noaiaie?anueea, 1994) ?aaeyoue i?ecia/aoe i?e e?eoaaii? i?ci?o
aanoic?a aioeaa?aaaioi? oa niaciie?oe/i? i?aia?aoe. Ii?yae c oeei,
na?aae aioeaa?aaaio?a, ye? iae/ano?oa canoiniaothoue o no/ani?e
aeooa?nuee?e i?aeoeoe?, aeei?enoiao?oueny eo?aio?e, yeee a?aeiinii
i?ioeiieacaiee, oa o?aioae, yeee i?ioeiieacaiee i?e aaa?oiino?. Oiio
iiooe iiaeo i?aia?ao?a, ye? aeicaieyoue iaiaaeeoe aeei?enoaiiy
aeuaia?a?aoiaaieo e?e?a, ? aeooaeueiei.

O ca’yceo c oeei, aacoth/enue ia no/anieo aeaieo e?oa?aoo?e ?
?acoeueoaoao aeanieo aeine?aeaeaiue, ie aeaui ci?noeee aeoeaioe a
i?io?eaeoeoe? ?icaeoeo i?ci?o aanoic?a o aa-a?oieo, a naia canoiniaoaaee
nenoaiio aiceiioa?ai?th, aeoiaey/e c iniiaieo iaoiaaiaoe/ieo i?e/ei
aeieeiaiiy oe??? iaoieia??.

Ioaea, iaaaaeai? aeai? na?ae/aoue i?i oa, ui iiaeaeueoa aea/aiiy
ieoaiue, ye? noinothoueny aaiaoe/ii? noeeueiinou aei aeieeiaiiy i?ci?o
aanoic?a, niaaeeiaeo iniaeeainoae aoaeiae i?e?ioee?eoeyoi?iiai ?onea,
aeaieo ai?iiiaeueiiai oa a?io?i?/iiai noaoono aaa?oieo, aeyaeaiiy
no/anieo oaeoi??a ?eceeo oa i?iaaaeaiiy nai?/anii? ei?aeoe?? ci?i, ye?
iia’ycai? c aeaiith iaoieia??th, ? iaaecae/aeii aeooaeueieie.

C’aycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie

Aeena?oaoe?eia ?iaioa aeeiiaia a ?aieao iaoeiai? oaiaoeee eaoaae?e
aeooa?noaa oa a?iaeieia?? ?1 A?iieoeueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo ?i. I.?.Ie?iaiaa: “Ee?i?ei-iaoaiaoe/i? iaoiaee
i?iaiicoaaiiy, i?io?eaeoeee, e?eoaaiiy aeayeeo aeae?a aeooa?nueei? ?
a?iaeieia?/ii? iaoieia?? aiane?aeie ae?? oaeoi??a ciai?oiueiai
na?aaeiaeua ? ae?iaieoeoaa”, 1996-2000 IAe? A?iieoeueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo ?i. I.?.Ie?iaiaa. Oeo? oaie:
616-099:616,621-08:547.23. ? aea?ae?a?no?aoe?? 196U 04907, ea??aiee oaie
— caa. eaoaae?e, i?ioani? A.O.Iaci?/oe.

Iaoa aeine?aeaeaiiy

Cieaeaiiy iaoa?einueei?, ia?eiaoaeueii? caoai?thaaiino? oa
ia?eiaoaeueii? nia?oiino? i?e i?ci?o aanoicao ia i?aenoaa? ?ic?iaee
eiiieaeniiai iaoiaeo i?iaiicoaaiiy, i?io?eaeoeee ? e?eoaaiiy i?ci?o
aanoic?a ia iniia? iiaeeaeaiiai aea/aiiy nenoaie iaoe-ieaoeaioa-ie?ae oa
noaio iiaiia?iaeaeaiiai.

Caaea/? aeine?aeaeaiiy:

1. Aecia/eoe /anoioo i?ci?o aanoic?a a no/anieo oiiaao.

2. Aea/eoe oaeoi?e ?eceeo aeieeiaiiy i?ci?o aanoic?a o aaa?oieo,
iniaeeaino? ia?aa?ao aaa?oiino?, iieia?a oa no?oeoo?o oneeaaeiaiue, ye?
iathoue i?noea i?e aeai?e iaoieia??.

3. Aea/eoe iniaeeaino? niiaoioeio ca O?o-Ea?oa?ii o ae?iie c oe??th
iaoieia??th.

4. Aecia/eoe iieacieee ai?iiiaeueiiai noaoono aaa?oieo aeine?aeaeoaaieo
a?oi c aeeth/aiiyi aecia/aiiy ??aiy i?iaanoa?iio, ano?aae?ieo, ano??ieo,
ei?oecieo, ieaoeaioa?iiai eaeoiaaio, i?ieaeoeio, o??aio?ii?io,
o?eeiaeo??ii?io, o??ien?io.

5. Aea/eoe iniaeeaino? a?eo?ioeeoa?ieo aioeaai?a e?ia? ca nenoaiaie
AAI, IN, ?, Rh ? aaioiaeia?iii ne?iaaoee o aaa?oieo c i?ci?ie aanoicaie.

6. Aecia/eoe /anoioo oa aieea aiaei- ? aeciaai?? ia aeieeiaiiy i?ci?o
aanoic?a o ae?iie.

7. Aeyaeoe ei?aeyoe?ei? ca’ycee i?ae aeuacaaaeaieie iieacieeaie i?e
cacia/ai?e iaoieia?? c iiaeaeueoei iiaoaeoaaiiyi iaoaiaoe/ii? iiaeae?.

8. Ia iniia? io?eiaieo aeaieo ?ic?iaeoe e?eoa??? ?iaeea?aeoaeueiiai
i?iaiicoaaiiy iaoieia??, ui aea/a?oueny.

9. Iaoeiai iaa?oiooaaoe eiiieaen i?io?eaeoe/iiai e?eoaaiiy c
canoinoaaiiyi nenoaiieo aiceiieo i?aia?ao?a o ae?iie c oaeoi?aie ?eceeo
aeieeiaiiy i?ci?o aanoic?a.

10. Ai?iaaaeeoe cai?iiiiiaai? iaoiaeeee i?iaiicoaaiiy oa i?io?eaeoe/iiai
e?eoaaiiy a i?aeoeeo ioi?iie caei?ia’y.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a

Aia?oa aea/ai? iniaeeaino? niiaoioeio ae?iie c ??cieie nooiaiyie
oyaeeino? i?ci?o aanoic?a ca iiaeeo?eiaaiith iaoiaeeeith O?o-Ea?oa?a,
ye? oa?aeoa?ecothoueny ciaioaiiyi L-eiiiiiaioo (e?noeiaiai) ? c?inoaiiyi
F-eiiiiiaioo.

Anoaiiaeaii, ui iaeneiaeueia /anoioa cono??/? anioe?aoe?e
a?eo?ioeeoa?ieo aioeaai?a e?ia? ca 5 nenoaiaie o aaa?oieo c i?ci?ie
aanoicaie oa?aeoa?eco?oueny iayai?noth: 0(I) IN ?(+) Rh(+) I? 2-1; 0(I)
IN ?(+) Rh(+) I? 2-2; 0(I) I ?(+) Rh(+) I? 2-2.

Aia?oa aeiaaaeaii, ui na?aae ae?iie c i?ci?ie aanoicaie /ano?oa
cono??/athoueny aiaeiaaii? oethae, ui na?ae/eoue i?i aaaiiee aianie
niaaeeiaino? o ?icaeoie oe??? iaoieia??.

Aia?oa a eiiieaen? ioe?iaii eiinoeoooe?th aaa?oieo ae?iie c i?ci?ie
aanoicaie c o?aooaaiiyi niiaoioeio, iniaeeainoae i?e?ioee?eoeyoi?iiai
?onea, ?iaeea?aeoaeueiiai ai?iiiaeueiiai i?io?eth, a?io?i?/ieo
iieaciee?a, aaiaoe/ieo ia?ea??a (niieo/aiiy a?eo?ioeeoa?ieo aioeaai?a
e?ia?, aieeao aiaei- oa aeciaai??) ? ia iniia? oeueiai i?iaaaeaii
?iaeea?aeoaeueia iaoaiaoe/ia iiaeaethaaiiy oa i?iaiicoaaiiy aeieeiaiiy
i?ci?o aanoic?a.

Aeiiiaiaii aaaaoieaioethaiaee iaoiaaiac i?ciueiai aanoico aieeaii
aaiaoe/ieo oaeoi??a ia i?e?ia?o?oaeoii?eo ? ai?iiiaeueiee i?io?eue
aaa?oieo oa ooieoe?? ueoiaeaeii? caeice ia noai ?aieia?/ieo iieaciee?a.

Iaoeiai iaa?oioiaaii aeioe?euei?noue i?ecia/aiiy i?i-o?eaeoe/iiai
e?eoaaiiy c canoinoaaiiyi nenoaiii? aiceiioa?ai?? aeey ei?aeoe??
i?e?ioee?eoeyoi?ieo oa ?aieia?/ieo ii?ooaiue o aaa?oieo c i?ci?ie
aanoicaie.

I?aeoe/ia cia/ou?noue iaea?aeaieo ?acoeueoao?a

Cai?iiiiiaaia iiaa, a?eueo aoaeoeaia iaoiaeeea ee?i?ei-iaoaiaoe/iiai
iiaeaethaaiiy ? ?iaeea?aeoaeueiiai i?iaiicoaaiiy i?ci?o aanoic?a, yea
a?aoiao? aeai? niiaoioeio aaa?oii?, niieo/aiiy a?eo?ioeeoa?ieo aioeaai?a
e?ia?, ai?iiiaeuei? iieacieee, noai i?e?ioee?eoeyoi?iiai ?onea,
iieacieee aiaei- oa aeciaai??.

?acoeueoaoe ai?iiiaeueieo iieaciee?a (i?iaanoa?iio, ano?aae?ieo,
ano??ieo, ieaoeaioa?iiai eaeoiaaio, i?ieaeoeio, ei?oecieo, o??aio?iiiiai
ai?iiio, O3 oa O4) o aeeiai?oe? o?c?ieia?/iiai ia?aa?ao aaa?oiino? oa o
ae?iie c i?ci?ie aanoicaie iiaeooue aooe aeei?enoai? ye aeiiii?aei? a
ae?aaiinoeoe? , aecia/aii? nooiaiy oyaeeino? oa i?iaiicoaaii? oe???
iaoieia??.

Aeei?enoaiiy eii’theoeaaeueii? a?ii?e?ineii?? aeey i?eaeeoo?aiai
aeeiai?/iiai niinoa?aaeaiiy ca noaiii i?e?ioee?eoeyoi?iiai ?onea ?
i?e?ioee?eoeyoe?? e?ia? o aaa?oieo c i?ci?ie aanoicaie aeicaiey?
ioe?ithaaoe nooi?iue oyaeeino? i?ciueiai aanoico, aoaeoeai?noue
i?ecia/aiiai e?eoaaiiy oa aeioe?euei?noue i?ieiiaoaaiiy (/e ia?a?eaaiiy)
aaa?oiino?.

?ic?iaeaiee ? ai?iaaaeaeaiee a ee?i?/io i?aeoeeo iiaee aoaeoeaiee iaoiae
i?io?eaeoe/iiai eiiieaeniiai e?eoaaiiy c canoinoaaiiyi nenoaiii?
aiceiioa?ai?? o aaa?oieo a?oi i?aeaeuaiiai ?eceeo aeicaiey? caiia?aoe
aeieeiaiith oa i?ia?anoaaiith i?ciueiai aanoico oa eiai oneeaaeiaiue ca
?aooiie ii?iae?caoe?? i?e?ioee?eoeyoe?? oa ?aieia?/ieo iieaciee?a e?ia?.

Iniaenoee aianie caeiaoaa/a

Io?eiai? aeai? ? ?acoeueoaoii naiino?eii? ?iaioe aeena?oaioa. Aaoi?ii
naiino?eii i?iaiae?ciaaia iaoeiaa e?oa?aoo?a oa iaoaioia ?ioi?iaoe?y c
i?iaeaie i?ci?o aanoic?a o aaa?oieo.

?ic?iaeaii niaoe?aeuei? i?ia?aie niinoa?aaeaiue, aei yeeo a?aeiineoueny
aieaoa c aeaoaeueiei aecia/aiiyi oaeoi??a ?eceeo i?ciueiai aanoico ?
niiaoioeiieia?/ia ea?oa. I?iaaaeaii eiiieaenia ianoaaeaiiy 381 aaa?oii?
c iiaeaeueoei ?iciiae?eii ?o ia a?oie, caeaaeii a?ae iayaiino? i?ciueiai
aanoico c canoinoaaiiyi ee?i?/ieo, eaai?aoi?ieo oa ?ino?oiaioaeueieo
iaoiae?a aeine?aeaeaiiy.

Aeeiiaii niiaoioeiieia?/i? aeine?aeaeaiiy c iiaeaeueoei ia/eneaiiyi
io?eiaieo ?acoeueoao?a oa iiaoaeoaaiiyi a?ao?e?a. Caaacia/aii aeeiiaiiy
ai?iiiaeueieo aeine?aeaeaiue. Aeeiiaia a?ii?e?ineii?y
aoeueaieii’thieoeae iea c iiaeaeueoei ?? oioia?aooaaiiyi oa
?ic?aooieaie. I?iaaaeaii aea/aiiy aieeao aiaei- oa aeciaai?? o ae?iie oa
a?eo?ioeeoa?ieo aioeaai?a e?ia?.

Iniaenoi aeena?oaioii i?iaaaeaii noaoenoe/iee aiae?c ?acoeueoao?a
aeine?aeaeaiiy, iaienai? an? ?icae?ee aeena?oaoe??, noi?ioeueiaai?
aeniiaee oa i?aeoe/i? ?aeiiaiaeaoe??, caaacia/aia ?o ai?iaaaeaeaiiy a
iaaee/io i?aeoeeo oa a?aeia?aaeaiiy a iioae?eiaaieo i?aoeyo.

Ai?iaaoe?y ?acoeueoao?a aeine?aeaeaiiy

Iniiai? iieiaeaiiy ?iaioe aeiiia?aeaeenue ia iaoeiaeo eiioa?aioe?yo
A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (i. A?iieoey, 1997,
1998); can?aeaiiyo Ee?anueeiai oa A?iieoeueeiai iaeanieo a?aeae?eaiue
Oe?a?inueei? anioe?aoe?? aeooa??a-a?iaeieia?a (1996, 1997, 1998); ia O
c’?cae? aeooa??a-a?iaeieia?a Oe?a?ie (i. Iaeana, 1996); ieaioiao
i?aae?iiy anioe?aoe?? aeooa??a-a?iaeieia?a Oe?a?ie (i. *a?i?aoe?, 1997
oa i. ?aiaoi??y, 1998), ia II-o i?aeia?iaeiiio eiia?an? c ?ioaa?aoeaii?
aio?iiieia?? o i. A?iieoe? (1998), ia neiiic?oi? c i?aeia?iaeiith
o/anoth “Aeooaeuei? i?iaeaie ee?i?/ii? oa?iaeieia??” (i.A?iieoey, 1998).
Io?eiaii iaoaio ia aeiao?ae ? 98020808.

Aeena?oaoe?eia ?iaioa ai?iaiaaia ia ni?eueiiio can?aeaii? eaoaae?
aeooa?noaa oa a?iaeieia?? Iaoe?iiaeueiiai iaaee/iiai oi?aa?neoaoo.
?acoeueoaoe aeine?aeaeaiiy aeei?enoiaothoueny a i?aeoe/i?e ?iaio?
iieiaiaeo aoaeeie?a ?1,2 i.A?iieoe?, A?iieoeuee?e iaeani?e ee?i?/i?e
e?ea?i? ?i. I.?.Ie?iaiaa, oeaio?? iaoa?? oa aeeoeie i.A?iieoe? oa o
iaa/aeueiiio i?ioean? ia eaoaae?ao aeooa?noaa oa a?iaeieia?? ?1 oa ?2
A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i. I.?.Ie?iaiaa.

Ioae?eaoe??

Ca oaiith aeena?oaoe?? iioae?eiaaii 24 ?iaioe.

Ianya ? no?oeoo?a aeena?oaoe??

Aeena?oaoe?eia ?iaioa aeeeaaeaia ia 292 noi??ieao iaoeiiieno ?
neeaaea?oueny ?c anooio, iaeyaeo e?oa?aoo?e, aeeeaaeo iniiaieo iaoiaeee
aeine?aeaeaiue, 7 ?icae?e?a aeanieo aeine?aeaeaiue, aiae?co oa
ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiue, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e, a?ae?ia?ao?/iiai iieac/eeo e?oa?aoo?e, yeee ia?aoiao?
414 aeaea?ae, c yeeo 264 ?iicaiieo. Aeena?oaoe?y ?ethno?iaaia 48
oaaeeoeyie, 58 ?enoieaie ? a?ao?eaie.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy

Aeey ae??oaiiy iinoaaeaieo caaaeaiue eiiieaenii a o?aoueiio o?eiano??
aaa?oiino? ianoaaeaii 381 aaa?oio, c yeeo 150 caei?iaeo ae?iie c
ii?iaeueiei ia?aa?aii aaa?oiino? (eiio?ieueia a?oia) ? 231 c ??cieie
nooiaiyie oyaeeino? i?ciueiai aanoico (iniiaia a?oia): ?c ieo 160 ae?iie
aoee c i?aaeeaiin??th eaaeiai nooiaiy — I-a?oia, 71 c i?aaeeaiin??th
na?aaeiueiai oa oyaeeiai nooiaiy — II a?oia.

O an?o ae?iie, ii?yae c caaaeueiii?eeiyoeie ee?i?ei-eaai?aoi?ieie,
?ino?oiaioaeueieie iaoiaeaie aeine?aeaeaiiy oa iaeyaeaie noi?aeieo
niaoe?ae?no?a (iaa?iiaoieia, oa?aiaao, ieoe?no), aeine?aeaeoaaee ai?no a
ne?iaaooe? e?ia? ano?aae?ieo, ano??ieo, i?iaanoa?iio, i?ieaeoeio,
ei?oecieo, ieaoeaioa?iiai eaeoiaaio, o??aio?iiiiai ai?iiio,
o?e-eiaeo??ii?io, o??ien?io iaoiaeii ?aae?i?ioiiiai aiae?co c
aeei?enoaiiyi iaai??a ?aaeoea?a eaai?aoi??? o?i?? a?eeiaeo ai?iii?a
?inoeoooo a?ii?aai?/ii? o?i?? AI A?ea?on?.

Aecia/aee oaeiae ii/aoie, e?iaoeue oa /an cai?oaiiy e?ia?, aaiaoie?eo,
i?io?iia?iiaee ?iaeaen, /an ?aeaeueoeeo?eaoe?? ieacie, eiioeaio?aoe?th
o?a??iiaaio, e?euee?noue o?iiaioeeo?a, aa?aaaoe?th o?iiaioeeo?a,
o?a??iiaai A.

C iaoith aeae?eaiiy aiaei- ? aeciaaiieo a?oi aaa?oieo ei?enooaaeenue
iiaeaeeth, yea a?aoiaoaaea iioiaeaeaiiy i?aaee?a (A.A.Ieeeothe,
A.E.Oeeeiia, 1975). E??i oeueiai, aea/aeenue a?eo?ioeeoa?i? aioeaaie
e?ia? ca 5 nenoaiaie (AAI, ?acon oaeoi?, IN, ? ? aaioiaeia?i ne?iaaoee
e?ia?) c iiaeaeueoith ioe?ieith ?o iiaeeeaeo niieo/aiue.

Aeey aea/aiiy niiaoioeio aeei?enoiaoaaee iiaeeo?eiaaio iaoiaeeeo,
cai?iiiiiaaio A.O?o ? Ae. Ea?oa?ii (1969), yea aeicaiey? ioe?ieoe
iniaeeaino? noaoo?e ?iaeea?aeooio aeeth/ath/e aecia/aiiy o?ueio
eiiiiiaio?a neeaaeo o?ea ethaeeie (aiaei-, iaci- ? aeoiii?oiiai).

Aaiaoe/i? oa niiaoioeiieia?/i? aeine?aeaeaiiy, ee?i?ei-iaoaiaoe/iee
aiae?c i?iaiaeeeenue o iaoeiai-aeine?aeiiio oeaio?? A?iieoeueeiai
iaaee/iiai oi?aa?neoaoo ?i.I.?.Ie?iaiaa (ea??aiee — ae.i.i., i?io. Eiaai
A.E.).

Aeine?aeaeaiiy i?e?inoaeei eii’thieoeae iea cae?enithaaee iaoiaeii
aoeueaii?e?iaia?ineii?? ca aeiiiiiaith oioiu?eeiii? eaiie UEO-56 a
i?ea?iaeuei?e iiaeeo?eaoe??. Ia?aiao?e i?e?inoaeei ?ic?aoiaoaaee ia
oioiiaaaoeaao.

Aeey e?euee?nii? ? ye?nii? ioe?iee cia/ouino? aeine?aeaeoaaieo oaeoi??a
?eceeo, ee?i?/ieo aeaieo ? aaiaoe/ieo iciae oa ?o aca?iica’yceo i?e
i?ci?o aanoicao ? iiaeaeueoiai iaoaiaoe/iiai iiaeaethaaiiy
aeei?enoiaoaaee nenoaio iaoi?ioi?iaoeee (iaeao i?eeeaaeieo i?ia?ai) ca
?.A.Aoae??ii oa nenoaio aeenia?n?eiiai ? aeene?ei?iaioiiai aiae?co.

O 49 ae?iie c oaeoi?aie ?eceeo aeieeiaiiy i?ci?o aanoic?a ? i?e
anoaiiaeai? ae?aaiico ??ciiai nooiaiy oyaeeino? oe??? iaoieia?? iaie
i?ecia/aeinue i?io?eaeoe/ia aai iaoiaaiaoe/ia e?eoaaiiy aiceiieie
i?aia?aoaie (aiaaiceiii). Ia?aeaeueii i?iaiaeeeinue niinoa?aaeaiiy ca
ae?ieaie a?oie ii??aiyiiy (30), aea ae?iee io?eioaaee caaaeueiii?eeiyoa
e?eoaaiiy (ca?aeii iaoiaee/ieo ?aeiiaiaeaoe?e IIC Oe?a?ie)
(a?iioaiceai?, naaeaoeai?, na/ia?ii? i?aia?aoe, i?aia?aoe, ye?
iie?auothoue ieiaeiai-ieaoeaioa?iee e?iaiia?a: eo?aio?e, anaioe?aea,
o?aioae, aoo?ee?i, aeooai?iiao eeneioo, a?oai?i A, A6).

Ioe?iea aaeaeaaoiino? ? aoaeoeaiino? canoiniaaieo iaoiae?a e?eoaaiiy
i?iaiaeeeanue ca aeiiiiiaith ee?i?/iiai oa eaai?aoi?iiai iaoiae?a
aeine?aeaeaiiy aei ii/aoeo e?eoaaiiy oa i?ney eo?no aeuacaaaeaiii?
oa?ai??.

Iaoaiaoe/io ia?iaea /eneiaeo aeaieo aeeiioaaee ia ia?niiaeueiiio
eiii’thoa?? “Pentium 233” ca aeiiiiiaith noaiaea?oiiai i?ia?aiiiai
iaeaoo “Statistics 5,0” aeey Windows 95.

Iniiai? ?acoeueoaoe aeine?aeaeaiiy

Aiae?c 4800 ?noi??e iieia?a iieacaa, ui o caei?iaeo ae?iie /ano?oa
anueiai i?ci?e aanoic aeieeaa o oa?i?i? 33-37 oeaei?a aaa?oiino?, ui
a?aeiia?aea? aeaiei e?oa?aoo?e (A.A.Aa?ai/aiei, 1992; E.N.Neaei?iaa,
1996; A.E.Noaiaieianeay, 1996) ? noaiiaea 6,4-7,6% ca /an aeeiiaiiy
aeena?oaoe?eii? ?iaioe. I?e aecia/aii? nooiaiy oyaeeino? i?ci?o aanoic?a
aaa?oieo oae? ee?i?/i? neiioiie, ye ??aaiue aei??thaaiiy AO ?
ae?aaeai?noue iaa?ye?a, ia caaaeaee aoee a??ia?aeieie ia a?aei?io a?ae
aaee/eie i?ioa?io???, ca ??aiai yei? ie a iniiaiiio ? anoaiiaethaaee
oyaee?noue iaoieia??.

I?e ii??aiyii? oaeoi??a ?eceeo oa iieaciee?a no?oeoo?e oneeaaeiaiue
aaa?oiino? oa iieia?a aaa?oieo iniiaii? oa eiio?ieueii? a?oi
anoaiiaeaii, ui ae?iee-neoaeaiaoe? a a?oi? c i?ci?ie aanoicaie
cono??/aeenue a 53,68% (i?ioe 40,0% a eiio?ieuei?e, ?<0,05), iaee iacaaeia?eueio iaoa??aeueio caaacia/ai?noue 41,99% (i?ioe eiio?ieueii? a?oie - 28,0%, ?<0,05), c ianith o?ea a?eueoa 70 ea - 39,83% (29,34% a eiio?ieuei?e a?oi?, ?<0,05). O 10,63% ae?iie c i?aaeeain??th eaaeiai nooiaiy a aiaiiac? iaee i?noea caiaeuei? caoai?thaaiiy iaoee oa aeiaeaoe?a, i?e i?aaeeain?? na?aaeiueiai ? oyaeeiai nooiaiy oeae iieaciee noaiiaea 46,48% (a eiio?ieuei?e a?oi? - 2,0%, ?<0,01), ieiia?eueia oa ooo/ia ia?a?eaaiiy aaa?oiino? a I-?e a?oi? o?aieyeiny o 26,88%, a II-?e a?oi? 30,99% (a eiio?ieuei?e 3,34%, ?<0,01)oa iaie?aeaey a I-?e a?oi? 7,5%, a ??-a?e a?oi? 2,82% (a eiio?ieuei?e a?oi? 1,39%, ?<0,01; ?<0,05). Ii??aithth/e aioo??oiueioo?iaiee noai ieiaea o ae?iie aeine?aeaeoaaieo a?oi, ie anoaiiaeee, ui e?euee?noue ae?iie eiio?ieueii? a?oie c ii?iaeueiei aioo??oiueioo?iaiei noaiii ieiaea (caaaeueia noia aae?a ca oeaeith Aioue? a?ae 8 oei 10 aae?a) neeaaeaea 93,2%, ae?iie c i?ci?ie aanoicaie (ia?oi? a?oie) - 75,81%; ae?oai? a?oie - 61,21% (?<0,05). Na?aaei?e oa?i?i o?eaaeino? aanoico aaa?oieo aei iiiaioo ?ic?iaeaeaiiy noaiiaea o I a?oi? 19,9±3,7 aei?a, a II a?oi? 8,2±2,1 aei?a (?<0,001). Iaioee oa?i?i o?eaaeino? i?ciueiai aanoico aei iiiaioo ?ic?iaeaeaiiy a ??-a?e a?oi? coiiaeaiee oyaee?noth caoai?thaaiiy, oi?noaaiiyi aaaeaiiy aaa?oiino? ? ?iae?a ?c canoinoaaiiyi aei?iaeiai? i?aeaioiaee oa ?iaeinoeioeyoe?? oa i?e iaiao?aeiino? iia?aoeaiiai ?ic?iaeaeaiiy. O?eaae?noue iieia?a o eiio?ieuei?e a?oi? aoea o ia?oi?iaey/eo ae?iie 11,4±1,4 aiae., o iiaoi?ii?iaey/eo - 8,3±1,3 aiae. O ia?oi?iaey/eo ae?iie c i?ci?ie aanoicaie I-i? a?oie - 12,8±2,4 aiae., o iiaoi?ii?iaey/eo 9,6±2,1 aiae, a a ae?oa?e a?oi? a?aeiia?aeii 9,4±2,3 aiae ? 6,7±1,9 aiae. O ae?iie eiio?ieueii? a?oie ia?iaeeeinue aeeaeie 150 iiaiia?iaeaeaieo c na?aaeiueith ianith o?ea 3422±212,8 a ? aeiaaeeiith o?ea 50,7±3,1 ni. Ioe?iea ca oeaeith Aiaa? o ieo neeaaeaea 8,7±0,8 aaea. I?e i?aaeeain?? eaaeiai nooiaiy ?c 160 iieia?a ia?iaeeeiny aeeaeie 161 (iaeia aea?eiy) iiaiia?iaeaeaieo ?c na?aaeiueith ianith o?ea 3418±198,1 a, aeiaaeeiith o?ea 51,3±2,8 ni ? ioe?ieith ca oeaeith Aiaa? - 8,4±0,7 aaea. I?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaiy ia 71 ?iaee aeeaeie ia?iaeeeenue 70 iiaiia?iaeaeaieo c n?aaeiueith ianith o?ea 2760±128,5 a (?< 0,05), aeiaaeeiith o?ea 48,1±2,3 ni (?>0,05),
na?aaeiueith ioe?ieith ca oeaeith Aiaa? 6,4±0,4 aaee (?<0,05). Oaeei /eiii, i?e i?ci?o aanoicao aaa?oieo a?aecia/a?oueny aeniea /anoioa aioo??oiueioo?iaii? o?ii?/ii? a?iien?? ieiaea oa ano?en?? iiaiia?iaeaeaiiai. Ui noino?oueny niinia?a ?ic?iaeaeaiiy ae?iie aeine?aeaeoaaieo a?oi, oi ?c 160 aaa?oieo c i?aaeeaiin??th eaaeiai nooiaiy naiino?eii ia?iaeeee 146 ae?iie (91,25%), ?iaee cae?i/eeeny iia?aoe??th eana?aaa ?icoeio o 14 ae?iie (8,75%). C 71 ae?iee ae?oai? a?oie naiino?ei? ?iaee a?aeaoeeny o 62 (87,32%) ae?iie, iia?aoeaiei oeyoii ?ic?iaeaeaii 12 (16,91%) ae?iie. Aiae?coth/e no?oeoo?o oneeaaeiaiue iieia?a oa i?neyiieiaiaiai ia??iaeo, iaiao?aeii a?aei?oeoe, ui i?e ?ic?iaeaeai? a eiio?ieuei?e a?oi? na?aaeiy e?iaiao?aoa neeaaeaea 326,8±19,4 ie, a ?-a?. ae?iie - 338,9±20,6 ie a II-?e a?. - 526,8±35,6 ie (?<0,05), /ano?oa iaei i?noea ianai?/ania a?aeoiaeaeaiiy iaaeieiieiaeiaeo aiae: 13,43% i?e i?ci?o aanoio, i?e ii??aiyii? c eiio?ieueiith a?oiith - 12,0%, aiiiae?? nei?i/oaaeueii? ae?yeueiino? iaoee a?aei?/aii i?e i?ci?o aanoicao a 15,15%, a ii??aiyii? c eiio?ieueiith a?oiith - 12,67%. I?e i?ci?o aanoicao iaie a?aei?/aii a?eueo aenieo /anoioo i?neyiieiaiaeo naioe/ieo oneeaaeiaiue: 3,03% aiaeii?iiao?eo?a, i?ioe 0,67% a eiio?ieuei?e a?oi? (?<0,05 ). O ?icaeoeo aaaaoueio iaoieia?/ieo i?ioean?a aa?ooue o/anoue ye aeciaaii?, oae ? aiaeiaaii? oaeoi?e. O iiai?e i??? oea noino?oueny e aaa?oiino? ye aaiaoe/ii aeaoa?i?iiaaiiai i?ioeano, ? i?ci?o aanoic?a, ye? ? oneeaaeiaiiyi aaa?oiino?. I?i oea na?ae/eoue ?aeaioe/i?noue a?eueoino? ?o ee?i?/ieo oa?aeoa?enoee c e?eoa??yie aeey caoai?thaaiue c ioeueoeoaeoi??aeueiei oeiii niaaeeiaino? (A.N.Na?aaaa, 1982). E??i oeueiai, cia/aiiy niaaeeiai? noeeueiino? a aaiac? aanoic?a iia’ycaia ia o?eueee c neeaaeiei oa?aeoa?ii oe??? noeeueiino?, aea e c aeayeeie iniaeeainoyie iaoieia??, ui aea/a?oueny. Ae?enii, ye a?aei?/athoue a?eueo?noue aaoi??a (A.E.Noaiaie?anueea, A.I.Aaioee?anueeee, 1994; A.I.Na?ia n niaao., 1997), on? neiioiie aanoico cieeathoue i?ney caaa?oaiiy aaa?oiino?, ui oneeaaeith? i?iaaaeaiiy iaiao?aeieo aeine?aeaeaiue. Ca?aeii aeaieo, ye? ?ic?iaeai? a IAeOe A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i. I.?.Ie?iaiaa A.E.Eiaaiii (1991), aeae?eythoueny aea? a?oie iciae i?e iaoieia?/ieo i?ioeanao: I - eiinoaooaaeuei? (ye? ci?iththoueny a i?ioean? iioiaaiaco - AO, iana o?ea, a?io?i?/i? ? ai?iiiaeuei? ia?aiao?e, oiui); II - i?iaiinoe/i? - noai?i aaiaoe/ii aeaoa?i?iiaai?, ye? ia caciathoue iioiaaiaoe/iiai aieeao - eaeeioeeoa?i? oa a?eo?ioeeoa?i? aioeaaie e?ia?, eie?? ?aeaeoaeii? iaieiiee, aea?iaoiae?o?/i? iieacieee oa ?yae ?ioeo. Aeey aeooa?noaa iaea?eueoee ?ioa?an iathoue ?iaeea?aeoaeueii niaoeeo?/i? aioeaaie (aeiaioeaaie) iniaeea? aaiaoe/ii aeaoa?i?iiaai? no?oeoo?e oeaiei, niaoeeo?/i?noue ? aca?iica’ycie yeeo aecia/athoue a?ieia?/io ?iaeea?aeoaeuei?noue i?aai?cio ana?aaeei? aeaeo (C.O.Aaneeue?aa, A.E.Oaaaeei, 1984; A.I.Ae?aiiee, A.I.Aeecee, 1990; S. Murrau et al., 1976; J. Dausset et al., 1978). Aaie, ye? eiio?ieththoue ?o oi?ioaaiiy a i?aai?ci?, ia?aaeathoueny niaaeeiai (A.E. Aoaeeiaa, 1981). A c’yceo c oeei, a oaeiae a?aoiaoth/e aenieo i?iaiinoe/io oe?ii?noue aea/aiiy ia?ea??a e?ia? ? a?aenooi?noue ii-ae?aieo ?ia?o i?e i?ciueiio aanoic?, iaie i?iaaaeaii aecia/aiiy ?o ia?ea?ii? ni?iiiaeiino? ? iiaeeeaiai anioe?aoeaiiai ca’yceo c iaoieia??th, ui aea/a?oueny. Aiae?coth/e io?eiai? ?acoeueoaoe, anoaaeaii, ui o aaa?oieo c i?ci?ie aanoicaie /ano?oa cono??/a?oueny 0(I) a?oia e?ia? (38,20%). O a?oi? c ii?iaeueiei ia?aa?aii aaa?oiino? ia?aaaaeathoue ae?iee c A (II) a?oiith e?ia? - 39,09%. sse a eiio?ieuei?e, oae ? a iniiai?e a?oi? ia?aaaaeaee ae?iee c Rh+ oeiii e?ia? (90,44% ? 86,36%). A iniiai?e a?oi? /anoioa ae?iie c a?oiith e?ia? MN neeaea 48,3%, a eiio?ieuei?e - 56,36% (?<0,06), c a?oiith e?ia? II - 34,26% (a eiio?ieuei?e 26,36%; ?<0,05). I?e aea/aii? a?oi e?ia? nenoaie ? niinoa??aa?oueny ia?aaaaa ye a iniiai?e (52,81%), oae ? a eiio?ieuei?e a?oi? (63,64%) “?+” iaae “?-” (47,19% ? 36,36%). I?e oeueiio o aa-a?oieo c i?ci?ie aanoicaie “?+” cono??/a?oueny a??ia?aeii ??aeoa (?<0,05), i?ae i?e ii?iaeueiiio ia?aa?ao aaa?oiino?. O aaa?oieo c i?ci?ie aanoicaie eiinoaoiaaii ca?eueoaiiy /anoioe ae?iie c oaiioeiii aaioiaeia?io I? 2-2 (47,19%), a oie /an, ye i?e ii?iaeueiiio ia?aa?ao aaa?oiino? ia?aaaaea? oaiioei aaioiaeia?io I? 2-1 (40,00%). E??i ie?aieo a?eo?ioeeoa?ieo ? ne?iaaoi/ieo aioeaai?a e?ia?, o aaa?oieo c ii?iaeueiei ia?aa?aii aaa?oiino? oa oneeaaeiaiei i?ci?i aanoicii iaie aecia/aia ?o noeoii?noue. Aea/aiiy anioe?aoe?e aioeaai?a e?ia? ?icoe?th? ?ioi?iaoe?th i?i ?iaeea?aeooi, aeyaey? ?noeiii aeii?ioth/? anioe?aoe??, ciaioo? aieea aeiaaeeiaeo niieo/aiue, aeicaiey? aeae?eeoe ?c on?o eiia?iaoe?e ?yae ia?ea??a, ye? oa?aeoa?i? aeey ae?iie c a?oie ?eceeo aeieeiaiiy i?ci?o aanoic?a. Anioe?aoe?? aioeaai?a e?ia? aoee ioe?iai? ca 2-o, 3-o, 4-o ? 5-oe eiiiiiaioieie nenoaiaie. I?e ioe?ioe? oaeoi??a ca aeaioeiiiiiaioiith nenoaiith i?e ii?iaeueiiio ia?aa?ao aaa?oiino? ia?aaaaeaee niieo/aiiy: A(II) I? 2-2 24,3%, A(II) Rh(+) 34,08%; A(II) P(+) - 37,34%; A (III) Rh(+) - 15,64%; B(III)P(+) - 14,78%. O ae?iie c i?ci?ie aanoicaie - I(I) Rh(+) - a 46,09%; 0(I) I? 2-2 - a 30,44%; 0(I) MN - a 26,34%; 0(I) I a 13,74%; A (III) MN - a 6,13%; 0(I) P(-) - a 9,14%. I?e 3-o eiiiiiaioi?e ioe?ioe? anioe?aoe?e o ae?iie c ii?iaeueiei ia?aa?aii aaa?oiino? ia?aaaaeaee niieo/aiiy A(II) I?(+) - a 14,43%; A(II) MN P(+) - a 19,67% ; A (III) I P(+) a 7,97%, a a a?oi? ae?iie c i?ci?ie aanoicaie 0(I) MN P(+) a 13,92%; 0(I) I P(+) - a 7,47%; A (III) IN P(+) - a 5,92%. Ioe?ithth/e anioe?aoe?? aioeaai?a e?ia? ca /ioe?ia niieo/aiiyie, ie io?eiaee ianooii? ?acoeueoaoe: a eiio?ieuei?e a?oi? /ano?oa anueiai cono??/aeenue niieo/aiiy A(II) I P(+) Rh(+) a 8,54%; A(III)I P(+) Rh (+) - a 7,48%; A(II) MN P(+) Rh (+) - a 18,74%, a a iniiai?e a?oi? 0(I) MN P(+) Rh(+) - a 12,45%; 0(I) I P(+) Rh(+) - a 7,82%. I?e aecia/aii? niieo/aiue ca i’youeiy nenoaiaie a eiio?ieuei?e a?oi? /ano?oa anueiai niinoa??aaeenue niieo/aiiy A(II) MN P(+) Rh(+) I?2-1 - a 9,4%; A(II) I P(+) Rh(+) I?2-2 - a 7,11%; A(???) I P(+) Rh(+) I? 2-2 - a 4,83%. O a?oi? ae?iie c i?ci?ie aanoicaie niieo/aiiy aioeaai?a aoee ianooiieie 0(I) MN P(+) Rh(+) I? 2-1 - 14,21%; 0(I) MN P(+) Rh(+) I? 2-2 -a 5,84%; 0(I) I P(+) Rh(+) I? 2-2 - a 8,23%. Oaeei /eiii, a?aoiaoth/e aenieo i?iaiinoe/io oe?ii?noue aeaiiai iaoiaeo, eiai oe?iea canoinoaaiiy i?e i?iaiicoaaii? ?ioeo iaoieia?/ieo noai?a, ?o a?aeiinii eaaea ? iaeiicia/ia aecia/aiiy, aeinoaoiuei aenieo /anoioo o?aieyiiy a iiioeyoe?? aaaaea?ii ca aeioe?eueia aeei?enoaiiy iieacieea anioe?aoe?e aioeaai?a e?ia? aeey i?iaiicoaaiiy i?ci?o aanoic?a. Ae?oaei, ia iaio aaaeeeaei aniaeoii ioeueoeoaeoi??aeueieo caoai?thaaiue ? aea/aiiy eiinoeoooe?? ethaeeie, yea i?aeoe/ii ii?aeio?oueny c aaiaoeeith, oae ye ae??oo? aeecuee? c iath caaaeaiiy. Nooue a/aiiy i?i oeie eiinoeoooe?? iieyaa? a oiio, ui eiaeiiio ?c oei?a aeanoea? oa?aeoa?i? iniaeeaino? ia o?eueee a ia?aeiii aeae?eaieo aio?iiiiao?e/ieo iieacieeao, aea e o neeaae? o?ea, ae?yeueiino? ia?aiaeo ? aiaeie?eiieo nenoai, no?oeoo?? ? ooieoe?yo aioo??oi?o i?aai?a (A.I.O?enaioiaa, E.A.Aaoe, 1981; A.O.Eaaoei, A.A.Ieeiainyi, E.I.Iiaeaeei, 1985; A.I.Eieiaeie/aiei, 1988). Ca aeaieie I.I.O?eaoiaa (1988), eiie?aoi? niiaoioeie oa?aeoa?ecothoueny ??cieie iieacieeaie ?ioi?oaoo, ai?iiiaeueiith iane/ai?noth i?aai?cio, noeeuei?noth aei caoai?thaaiue, oiui. I?e aea/ai? eiinoeoooe?? aaa?oieo anoaiiaeaii, ui na?aaeiy aaeueia ioe?iea niiaoioeio aeey eiio?ieueii? a?oie neeaea F-5, 96±0,12 aaea; I - 4,38±0,16 aaea; L - 1,03±0,05 aaea. Aeyaeaii aeaa ia?aaaaeath/eo oeie aoaeiae o?ea: aiaeiii?o-iaciii?oiee oa iaciii?o-aiaeiii?oiee. Na?aaeiy aaeueia ioe?iea niiaoioeio aeey ia?oi? a?oie ae?iie c i?aaeeaiin??th eaaeiai nooiaiy noaiiaeea: F -7,10±0,18 aaea; I - 4,54±0,14 aaea; L - 0,73±0,06 aaea; aeey II a?oie aaa?oieo : F - 7,22a±0,15 aaea; I - 4,63±0,15 aaea; L - 0,74±0,04 aaea. Ia’?aeiaiiy aa??aoe?eieo ?yae?a a?oi c i?aaeeain??th eaaeiai nooiaiy oa i?aaeeain??th na?aaeiueiai oa oyaeeiai nooiaiy aeicaieeei ioe?ieoe na?aaei?e niiaoioei an??? a?oie ae?iie c i?ci?i aanoicii ye aiaeiii?o-iaciii?oiee. Oaeei /eiii, ca iaoeie aeaieie, i?ci? aanoice oa?aeoa?ecothoueny ca?eueoaiiyi F-eiiiiiaioo (aiaeiii?oiiai, aee?iaiai), oa ciaioaiiyi L-eiiiiiaioo (aeoiii?oiiai, e?noeiaiai), ui iiaea aooe iieeaaeaii a iniiao ?ic?iaie e?eoa???a i?iaiicoaaiiy iaoieia??, ui aea/a?oueny, a ii?aeiaii? c ?ioeie ia?aiao?aie, ye? oa?aeoa?ecothoue ?iaeea?aeoaeuei? iniaeeaino? i?aai?cio (i?e?ioee?eoeyoi?ia ?onei, iniaeeaino? ai?iiiaeueiiai noaoono, a?eo?ioeeoa?i? aioeaaie e?ia?). Ca inoaii? ?iee a a?ieia?/i?e ? iaaee/i?e iaooe? ana /ano?oa caa?oathoueny aei aiae?co aaoa?ieieaeueieo oetha?a, eio?? aacothoueny ia oaiiiai? aaoa?iceno. A?i iieyaa? a aeoeaaoe?? ?inoiaeo i?ioean?a ? i?aeaeuaii? aeeoo?ae?yeueiino? iauaaee?a ia?oiai iieie?iiy a?ae aaouee?a c iaaieie aaiaoe/ieie a?aei?iiinoyie. Aaoa?icen iaoiiaeaiee ? ia?aaoaeiaith aaiii? no?oeoo?e iiioeyoe?? ? ?icoe?aiiyi oethaieo ca’yce?a. I?e ii??aiyii? ae?iie c ii?iaeueiei ia?aa?aii aaa?oiino? oa i?ci?ie aanoicaie aiaei-? aeciaaiieo a?oi anoaiiaeaii, ui i?e ii?iaeueiiio ia?aa?ao aaa?oiino? aeciaaii? oethae niinoa??aaeeny a 41,78%, a aiaeiaaii? - a 58,22%. I?e i?ci?o aanoicao a?aei?/aii a 80,61% - aiaeiaaii? oethae ? a 19,39% - aeciaaii? (?<0,02). Ioaea, ia oii? iii??ii? aeciaai?? cia/ii ??aeoa aeieea? i?ci?e aanoic, ui coiiaeaii caoaeaiiyi oethaieo ca’yce?a ?, iiaeeeai, a cia/i?e i??? caeaaeeoue a?ae niaaeeiaeo oaeoi??a. sse a?aeiii, ai?no noa?i?aeieo ai?iii?a o e?ia? aaa?oieo ? aaaeeeaei iieacieeii ia?aa?ao aaa?oiino? oa noaio ieiaeo i?ae /an aaa?oiino?. Ca iaoeie aeaieie, i?e i?aaeeaiin?? eaaeiai nooiaiy (?en. 1) o ii??aiyii? c iieacieeii o caei?iaeo aaa?oieo a??ia?aeii i?aeaeuo?oueny ye ??aaiue ano??ieo (?<0,05), oae ? ??aaiue ano?aae?ieo (?<0,05). I?e i?aaeeain?? na?aaeiueiai oa oyaeeiai nooiaiy o ii??aiyii? c iieacieeaie caei?iaeo aaa?oieo a??ia?aeii ca?eueoo?oueny ??aaiue ano?aae?ieo ? ano??ieo (?<0,05). A oeueiio a?aeiioaii? iao? aeai? ni?aiaaeathoue c aeaieie e?oa?aoo?e (E.N.Neaei?iaa, 1996). E??i oeueiai o aaa?oieo c i?ci?ie aanoicaie aeyaeaii i?aeaeuaiiy ??aiy ano?iaai?a o e?ia? i?iii?oe?eii oyaeeino? caoai?thaaiiy. Io?eiai? iaie aeai? na?ae/aoue i?i oa, ui o caei?iaeo aaa?oieo i?e o?c?ieia?/iiio ia?aa?ao aaa?oiino? ??aaiue i?iaanoa?iio a e?ia? a III o?eiano?? neeaaeaa 213,66±9,31 iiieue/e. O aaa?oieo c i?aaeeaiin??th eaaeiai nooiaiy a?aeaoaa?oueny i?aeaeuaiiy ai?noo ??aiy oeueiai ai?iiio aei 218,64±9,23 iiieue/e, a i?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaith cieaeaiiy aei 215,50±9,31 iiieue/e. Io?eiai? iaie aeai? ni?aiaaeathoue c aeoieith ?yaeo aaoi??a (A.I.Aeoeyaaa, 1982; A.E.*aeea c ni?aaao., 1988) i?i oa, ui ooieoe?y ieaoeaioe i?e ii/aoeiaeo noaae?yo i?ciueiai aanoico i?aeaeuo?oueny, a c iineeaiiyi nooiaiy oyaeeino? aanoico cieaeo?oueny. Iaeiei c aaaeeeaeo iieaciee?a ooieoe?iiaeueiiai noaio oaoi-ieaoeaioa?iiai eiiieaeno ? ??aaiue ieaoeaioa?iiai eaeoiaaio o e?ia? aaa?oieo, oae ye naia ai?iiie a?eeiaiai iioiaeaeaiiy iineaaeththoue aca?iio aaeaioaoe?th iaoa?einueeiai ? ieiaeiaiai i?aai?cio aei ae?? a?noinoi?nieo ? ?ioiieo oaeoi??a, ye? cia/ii aeoea?cothoueny i?e i?ci?o aanoicao. Io?eiai? iaie ?acoeueoaoe na?ae/aoue i?i oa, ui o caei?iaeo aaa?oieo ai?no ieaoeaioa?iiai eaeoiaaio neeaaeaa 202,23±2,30 iiieue/e. I?e i?aaeeain?? eaaeiai nooiaiy 192,41±4,01 iiieue/e, a i?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaith a?aeaoaa?oueny a??ia?aeia cieaeaiiy ieaoeaioa?iiai eaeoiaaio a e?ia? aei 179,68±1,61 iiieue/e (?<0,05) i?iii?oe?eii nooiaith oyaeeino? oe??? iaoieia??. A inoaii? ?iee c?iaeai? ia?o? ni?iae aecia/aiiy ?ie? i?ieaeoeio o aaiac? ??cieo oneeaaeiaiue aaa?oiino? oa ?iae?a. C oe??th iaoith eiai ai?no aecia/aee i?e caa?ic? ia?aae/anieo ?iae?a, oaoiieaoeaioa?ii? iaaeinoaoiino?, i?ciueiio aanoic?, iooeeiao a?iio?co i?e aaa?oiino?. A?aoiaoth/e iiiaeeiie? ioae?eaoe?? c oeueiai ieoaiiy, oa aeai? Oaga S. (1982) i?i oa, ui neioac i?ieaeoeio a?aeaoaa?oueny ia eeoa o a?iio?c? aaa?oii?, a e a i?aai?ci? ieiaea oa ieaoeaio?, iiaeia i?eionoeoe ? eiai aieea ?acii c ?ioeie ai?iiiaie ia oaoiieaoeaioa?iee eiiieaen. Ca iaoeie aeaieie, i?e o?c?ieia?/iiio ia?aa?ao aaa?oiino? ai?no i?ieaeoeio neeaaeaa 5012,59±89,27 iiieue/e. I?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaiy ai?no i?ieaeoeio ca?eueooaaany aei 5252,55±67,30 iiieue/e (?<0,05). Ai?iiiii?iaeoeoth/a ooieoe?y ieaoeaioe aecia/a?, ye i?aaeei, aca?iia?aeiioaiiy i?ae i?aai?ciii iaoa?? ? ieiaea (A.I.Naaaeueaaa n niaao., 1991). Aaaeeeaei ai?iiiii, yeee a?aeiineoueny aei no?an?aae?coth/i? nenoaie ? a?aeia?aaeo? aaeaioaoe?ei? iiaeeeaino? i?aai?cio aaa?oii?, ? ei?oecie, yeee neioaco?oueny ye a ieaoeaio?, oae ? a i?aai?ci? ieiaea. I?e i?aeeaiin?? eaaeiai nooiaiy eiioeaio?aoe?y ei?oecieo noaiiaeea 1731,19±20,41 iiieue/e, ui nooo?ai a?ae??ciyei ?? a?ae eiioeaio?aoe?? i?e o?c?ieia?/iiio ia?aa?ao aaa?oiino? - 1611,64±43,9 iiieue/e (?<0,05). ?en 1. ??aaiue ai?iii?a oaoiieaoeaioa?iiai eiiieaeno o ae?iie aeine?aeaeoaaieo a?oi (III-o?eiano?) I?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaiy ai?no ei?oecieo a e?ia? aaa?oieo noaiiaea 1788,72±17,96 iiieue/e ? iaa a??ia?aeio ??cieoeth ii??aiyii ?c caei?iaeie aaa?oieie (?<0,05). ?acoeueoaoe aecia/aiiy ??aiy ai?iii?a ueoiaeaeii? caeice a e?ia? o caei?iaeo aaa?oieo ? aaa?oieo c i?ci?i aanoicii iieacaee, ui o aaa?oieo c i?aaeeaiin??th eaaeiai nooiaiy ??aaiue o??io?ii?io a e?ia? ii??aiyii c iieacieeaie o caei?iaeo aaa?oieo a??ia?aeii i?aeaeuo?oueny (?<0,05). Aiaeii/an a?aeaoeinue a??ia?aeia cieaeaiiy ??aith o??ieneio (?<0,01) oa ??aith o?eeiaeo??ii?io a e?ia? (?<0,01) i?e i?aaeeaiin?? eaaeiai nooiaiy ii??aiyii c iieacieeii o caei?iaeo aaa?oieo. sse iieacaee ?acoeueoaoe i?iaaaeaieo aeine?aeaeaiue, o aaa?oieo c i?aaeeaiin??th na?aaeiueiai oa oyaeeiai nooiaiy a?aeaoeenue a?eueo ae?aaeai? ci?ie ai?noo o??ai?aeieo ai?iii?a. O aaa?oieo oe??? a?oie ia o?eueee ii??aiyii c iieacieeii o caei?iaeo aaa?oieo, aea e ii??aiyii c iieacieeaie o ae?iie c i?aaeeaiin??th eaaeiai nooiaiy, a??ia?aeii cieaeoaaany ??aaiue o?eeiaeo??ii?io oa o??ieneio a e?ia? (?<0,01) (?en 2). ?en. 2. ??aaiue ai?iii?a ueoiaeaeii? caeice o ae?iie aeine?aeaeoaaieo a?oi (III-o?eiano?) Io?eiai? iaie aeai? aeine?aeaeaiiy ai?iiiaeueii? ooieoe?? o??ai?aeii? nenoaie i?e i?ci?o aanoicao ocaiaeaeothoueny c ?ai?oa i?iaaaeaieie aeine?aeaeaiiyie ?yaeo aaoi??a, ye? oaeiae aeacothoue ia i?yio caeaaei?noue ??aiy eiioeaio?aoe?? ai?iii?a ueoiaeaeii? caeice a?ae nooiaiy oyaeeino? aanoico (TH.TH.Aiaee, 1990; A.O.Iaoeeaeiinueea, 1991). Ca aeaieie A.I.Naaaeue?ai? (1991), E.?.Ooiaiiai? (1983), A.I.Aaioeeianeiai (1983), E.N.Neaei?iaie (1996), R.Voigt c? ni?a?ia?oieeaie (1983) aaaeeeaeie i?e/eiaie aeieeiaiiy i?ci?o aanoic?a ? iaaeinoaoi? e?iaiiinoa/aiiy ? iai?i ?a/iaei o ieaoeaio?, cie?aia ia ??ai? ni??aeueieo noaeei. I?aoethth/e a oeueiio iai?yieo, ie aea/aee iniaeeaino? eiinoeoooe?? o aaa?oieo c i?ci?ie aanoicaie, aeeth/ath/e i?e?ioee?eoeyoi?ia ?onei. I?e aea/aii? i?e?ioee?eoeyoi?iiai ?onea eii’thieoeae iea o caei?iaeo aaa?oieo a 18-20 oeae. aaa?oiino?, iaie ci?i i?e?ia?o?oaeoii?ee ? no?oeoo?e noaeei ia aoei aeyaeaii. O ae?oa?e iieiaei? o?c?ieia?/ii? aaa?oiino? (34-36 oeae.) aoei anoaiiaeaii cia/ia c?inoaiiy /enea ia?oocoth/eo eai?ey??a ? ca?eueoaiiy ia’?io an?o eaiie i?e?ioee?eoeyoi?iiai ?onea. E??i oeueiai anoaiiaeaii ca?eueoaiiy ae?aiao?o a?oa??ie ? i?aeai?ey??a (?<0,05; ?<0,05). O aaa?oieo c i?ci?i aanoicii oaea ia ?aii?o aoaiao aoee aeyaeai? a?aeiia?aei? ci?ie a i?e?ia?o?oaeoii?oe? noaeeiii? n?oee ? a no?oeoo?? ie?aieo noaeeiieo eaioetha?a ii??aiyii c aiaeia?/ieie iieacieeaie a a?oi? caei?iaeo aaa?oieo. I?e a?coaeueiiio iaeyae? caaaeueiee iaethiie noaeeiii? n?oee eii’thieoeae iea o aaa?oieo c i?ci?i aanoicii iaa aeaeyae a?eueo u?eueiiai ca ?aooiie aeeeaoaoe?? ? aeaoi?iaoe?? noaeei a?aeaiaey/iai eaioethaa. A?oa??iey?i? noaeeie oa?aeoa?ecoaaeenue i?aeaeuaiith aiaoey?ecaoe??th ? caeaeno?noth oiae?a. Iio?e o oeeo noaeeiao iaa ca?ienoee oa?aeoa?, ui na?ae/eoue i?i ciaioaiiy oaeaeeino? e?iaiia?ao. Ii?oiiao??y eooa iea iieacaea, ui ae?aiao? a?oa??ie ? ii?yaeeo o ae?iie c i?aaeeaiin??th eaaeiai nooiaiy noaiiaea 16,4±0,2 iei, o aaa?oieo c na?aaei?i oa oyaeeei nooiaiai i?aaeeaiin?? - 16,1±0,1 iei, ia a?aei?io a?ae aiaei-a?/iiai iieacieea o caei?iaeo aaa?oieo, yeee neeaaeaa 18,0±0,3 iei (?<0,05). Ae?aiao? a?oa??ie II-ai ii?yaeeo o ae?iie I oa II a?oie caeeoaany iaci?iiei. Eiao?oe??io iiia?a/ii? aeaoi?iaoe?? a oeeo noaeeiao o aaa?oieo c i?ci?ie aanoicaie aoa aeuei ? neeaaeaa a?aeiia?aeii - 26% ? 21% i?ioe 14% o caei?iaeo aaa?oieo. Iaea?eueo iaaeyaeieie o aaa?oieo c i?ci?ie aanoicaie aoee ci?ie a eai?ey?iiio ?one?. E?iaiia?a a eai?ey?ao eii’thieoeae aaa?oieo oe??? a?oie aoa oiia?eueiaiei, noaaaa ca?ienoei ? ia?a?eaenoei. Iaeii/anii a?aei?/aeenue iciaee aa?aaaoe?? oi?iaieo aeaiaio?a e?ia?. O aaa?oieo c i?ci?ie aanoicaie a 34-36 oeaei?a aaa?oiino? ie anoaiiaeee c?inoaiiy ae?eyiie eieaeueiiai caoaeaiiy noaeei I-ai ? II-ai ii?yaeeo ii??aiyii c a?eueo ?aii?ie no?ieaie aaa?oiino?. Oae, aeey a?oa??ie I-ai ii?yaeeo aaee/eia eiao?oe??ioo iiia?a/ii? aeaoi?iaoe?? neeaaeaea 40%, aeey a?oa??ie II-ai ii?yaeeo 26%. I?aeoe/ii o an?o aaa?oieo c i?ci?i aanoicii iio?e e?ia? iaaoaaa oa?aeoa?o ca?ienoiai ? ia?a?eaenoiai. A 30% niinoa?aaeaiue a a?oa??iey?ieo i?e?inoaeeiao a?aei?/aeenue iciaee aa?aaaoe?? oi?iaieo aeaiaio?a e?ia?. Ca aeaieie ii?oiiao??? o ae?iie I oa II a?oie anoaiiaeaii a??ia?aeia ciaioaiiy ae?aiao?o a?oa??ie ii??aiyii c aiaeia?/iei iieacieeii a a?eueo ?aii? oa?i?ie aaa?oiino?. Aiae?c ?acoeueoao?a ?aieia?/ieo aeine?aeaeaiue e?ia? iieacaa, ui c ia?inoaiiyi oyaeeino? i?ciueiai aanoico aaa?oieo iineethaaeenue ?o aaiieiaaoeyoe?ei? ii?ooaiiy ca ?aooiie nei?i/aiiy /ano cai?oaiiy e?ia?, oaeaeoiai ii/aoeo cai?oaiiy, cieaeaiiy /ano ?aeaeueoe?o?eaoe?? ieacie, ca?eueoaiiy eiioeaio?aoe?? o?a?eiiaaio, cieaeaiiy e?eueeino? o?iiaioeeo?a ii??aiyii c ae?ieaie eiio?ieueii? a?oie. Oiio, a?aoiaoth/e aeai? e?oa?aoo?e, oa ?acoeueoaoe iniaenoeo aeine?aeaeaiue, c iaoith a?eueo /?oei? ae?aaiinoeee ae?aaeaiino? iaoieia?/ieo ci?i i?e ??cieo nooiaiyo oyaeeino? i?ci?o aanoic?a, ie aeaui iiaeeo?eoaaee oeaeo ioe?iee i?e?ioee?eoeyoi?ieo ii?ooaiue iaoi/ii-ieaoeaioa?iiai eiiieaeno ca aeaieie i?e?ineii?? aoeueaieii’thieoeae, cai?iiiiiaaio A.I.Aaioee?anueeei ? A.A. AEaaoeiae/ai. E??i aeacaieo ia?aiao??a, aei oeaee ie aeeth/eee aeai? i?i aaiieiaaoeyoe?ei? ii?ooaiiy o ae?iie c i?ci?ie aanoicaie. Caaaeueia noia aae?a ii eiaeiiio aeaeo ii?ooaiue yaey? niaith ?iaeaen i?e?ioee?eoeyoe??. Ca?aeii oe??? oeaee ioe?iea i?e?ioee?eoeyoi?ieo ii?ooaiue noiith aei 10 aae?a a?aeii-a?aea? ?eceeo aeieeiaiiy i?ciueiai aanoico, aei 25 aae?a - eaaeiai nooiaiy, aei 35 aae?a - na?aaeiueiai nooiaiy oyaeeino? ? aeua 35 aae?a oyaeeiai nooiaiy i?ciueiai aanoico. Ca iaoeie aeaieie, na?aaeiy ioe?iea i?e?ioee?eoeyoi?ieo ii?ooaiue (?iaeaen i?e?ioee?eoeyoe??) i?aai?cio aaa?oii? a a?oi? ae?iie c i?aaeeain??th eaaeiai nooiaiy noaiiaeea -22,6±5,2 aaee, i?e i?aaeeaiin?? na?aaeiueiai - 31,5±8,4 aaee, i?e i?aaeeain?? oyaeeiai nooiaiy - 40,8±9,7 aaee (o caei?iaeo aaa?oieo 5,2±1,0,01, ?<0,05). A iao /an, a ee?i?/i?e iaaeeoeei? aeiee iiaee i?io?eaeoe/iee iai?yiie - i?iaiicoaaiiy iaoieia?? c aeei?enoaiiyi ee?i?ei-iaoaiaoe/ieo aeine?aeaeaiue. Oea iia’ycaii, c iaeiiai aieo, c iaiao?aei?noth iaoeiaiai aiae?co aaeeei? e?eueeino? iieaciee?a, ye? ciaoiaeyoueny a neeaaei?e caeaaeiino? iaeei a?ae iaeiiai, c ?ioiai aieo, canoinoaaiiy iaoaiaoe/ieo iaoiae?a aeicaiey? cia/ii i?aeaeueoe ye?noue ae?aaiinoeee oa i?iaiicoaaiiy. Oiio aaaaeaiiy o aea/aiiy i?ci?o aanoic?a i?iaiinoe/ieo iaoiae?a, ye? aecia/athoue nooi?iue a??ia?aeiino? aeieeiaiiy iaoieia??, aeicaiey? cae?enithaaoe ?iaeea?aeoaeueii aeeoa?aioe?eiaaio i?io?eaeoeeo ??. O ca’yceo c oeei, i?ney io?eiaiiy ?acoeueoao?a aea/aiiy aaaaoueio iieaciee?a oa oaeoi??a ?eceeo aeieeiaiiy i?ci?o aanoic?a, ie, iaoiaeii aeenia?n?eiiai aiae?co, aeine?aeeee aieea aaaiieo (ca iaoeie aeaieie) oaeoi??a ia iiaeeea?noue aeieeiaiiy i?ci?o aanoic?a ??ciiai nooiaiy oyaeeino?. A?aoiaoth/e ?ieue niaaeeiaeo oaeoi??a o aeieeiaii? i?ci?o aanoic?a iaie i?iaiae?ciaaii aieea ??cieo eiiiiiaio?a niiaoioeio ae?iee, ?? ai?iiiaeueieo oa a?io?i?/ieo iieaciee?a, iniaeeainoae noaio i?e?ioee?eoeyoi?iiai ?onea ia ?icaeoie i?aaeeaiin?? ??cieo nooiaiae oyaeeino?. Aiae?coth/e io?eiai? ?acoeueoaoe anoaiiaeaii, ui iaea?eueoee aieea ?c on?o eiiiiiaio?a niiaoioeio ia aeieeiaiiy ? ?icaeoie i?ciueiai aanoico ia? cia/aiiy aee?iaiai eiiiiiaioo, yeee neeaaea? 18,38%. Aeii?ioth/a cia/aiiy na?aae ai?iii?a ieaoeaioa?iiai eiiieaeno iaeaaeeoue i?iaanoa?iio, ei?oecieo oa ano??ieo, a ui noino?oueny ai?iii?a ueoiaeaeii? caeice, oi an? aiie iathoue aeinoia??ii aaaiiee aieea ia aeieeiaiiy oa ?icaeoie i?aaeeaiin??. Iaea?eueo nooo?aee aieea c a?io?i?/ieo iieaciee?a e?ia? aaa?oieo ia ?icaeoie i?aaeeaiin?? eaaeiai oa na?aaeiueiai nooiaiy iathoue iieacieee i?io?iia?iiaiai ?iaeaeno, caaaeueiiai a?eeo oa o?a?eiiaaio ne?iaaoee e?ia?. C on?o ia?a?aoiaaieo ia?aiao??a iaea?eueoa i?iaiinoe/ia cia/aiiy (96-98%) ia? ?iaeaen i?e?ioee?eoeyoe??. Ianooiiei aoaiii a i?iaiicoaaii? i?ci?o aanoic?a noaei ?o iaoaiaoe/ia iiaeaethaaiiy, yea cia/ii i?aeaeuo? ?ioi?iaoeai?noue io?eiaieo ?acoeueoao?a. Ca aeiiiiiaith iaoiiao?e/iiai aeai?eoio ie noai?eee i?iaiinoe/i? e?eoa??? aeieeiaiiy i?ci?o aanoic?a o aeaeyae? iao?a c eiaeiiai i?iaiicoth/iai ia?aiao?o. Ca aeiiiiiaith aeene?ei?iaioiiai aiae?co aoei aeaaaeaii oi?ioee iaoaiaoe/iiai iiaeaethaaiiy aeey a?eueo c?o/iiai canoinoaaiiy oe??? iaoiaeeee ia i?aeoeoe?. Aeey a?eueoi? c?o/iino? ? iaaeyaeiino? iaoaiaoe/io iiaeaeue cia?aaeoaaee ? a?ao?/ii (?en 3). Oi/i?noue ?iaioe io?eiaii? iiaeae? aeey i?iaiicoaaiiy aeieeiaiiy oa ioe?iee nooiaiy oyaeeino? i?ci?o aanoic?a ? aeinoaoiuei aenieith ? neeaaea? 98%. I?ney i?iaaaeaiiy ?iaeea?aeoaeueiiai i?iaiicoaaiiy oa iiaeaethaaiiy aanoic?a i?e iaiao?aeiino? nai?/anii i?ecia/aee eo?n i?io?eaeoe/iiai e?eoaaiiy. Nie?ath/enue ia no/ani? iaoeia? aeai? i?i i?ia?aeio ?ieue ii?ooaiue a i?e?ioee?eoeyoi?iiio ?one?, i?i iaoieia?/io a?ia?eiaaoeyoe?th ? oi?ioaaiiy o?ii?/iiai AeAC-neiae?iio i?e i?ci?o aanoicao oa aeai? aeanieo aeine?aeaeaiue noaio i?e?ioee?eoeyoi?iiai ?onea, ie i?eeoee aei aeniiaeo, ui iaiao?aeii a ia?oo /a?ao canoiniaoaaoe i?aia?aoe aioeaa?aaaioii? ae??, ye? iie?auothoue ?aieia?/i? aeanoeaino? e?ia?, a?aeiiaeththoue i?e?ioee?eoeyoi?iee e?iaiia?a, ia oii? cania?a, ye? ii?iae?cothoue a?eeiaee neeaae ieacie, ?aaoeththoue ?ioiieia?/i? aca?iia?aeiineie, oae ye ca aeaieie aaaaoueio aaoi??a i?ci? aanoice a?aeiinyoueny aei aooi?ioiieo caoai?thaaiue (I.A.AEo/aiei, 1988; E.N.Neaei?iaa, 1996; A.I.Aaioeeianeee, 1995). Nenoaii? aiceii? i?aia?aoe aa?ooue o/anoue oaeoe/ii o an?o aeuaia?a?aoiaaieo i?ioeanao: ae?thoue ia ie?ai? eiiiiiaioe nenoaie ?ioi?oaoo ? aeeeeeathoue ?oeioaaiiy ? i/euaiiy i?aai?cio a?ae ?ioiieo eiiieaen?a, ye? ooai?ththoueny i?e i?ci?o aanoicao, ?aaoeththoue cai?oaiiy e?ia?, o?a?eiiaaiac, noaeeiiee oiion, a?oa??aeueiee oene, ae?yeuei?noue iiceo, i?aeee?oeii? aca?iiae??. Nenoaiiee aiceiiee i?aia?ao aiaaicei, yeee ie canoiniaoaaee o eiiieaeniiio e?eoaaii?, i?noeoue a nia? eiia?iaoe?th aenieiaeoeaieo aicei?a ?ineeiiiai oa oaa?eiiiai iioiaeaeaiiy ? ia? cia/iee i?ioeiaa?yeiaee, ?ioiiiiaeaethth/ee oa aoi?eiii aiaeaacoth/ee aoaeo. Iaea?eueo oe?iiith aeanoea?noth oeueiai i?aia?aoo naia i?e i?ci?o aanoicao ? iie?auaiiy ?aieia?? e?ia? ca ?aooiie ii?iae?caoe?? ?? a’yceino? oa i?e?ioee?eoeyoe?? o ca’yceo c ?oeioaaiiyi ooai?aieo o?iia?a. A ?acoeueoao? eiai ae?? iie?auo?oueny caaacia/aiiy oeaiei eeniai ? iiaeeaieie ?a/iaeiaie, oaeei /eiii a?aeiiaeth?oueny i?e?ioee?eoeyoe?y. Aeoiaey/e c oeueiai, c iaoith i?io?eaeoeee oa e?eoaaiiy ii?ooaiue i?e?ioee?eoeyoi?iiai ?onea o ae?iie c ??cieie nooiaiyie i?ciueiai aanoico ie i?ecia/aee aiaaicei ia oii? caaaeueiii?eeiyoiai e?eoaaiiy a ??ci? no?iee aaa?oiino? caeaaeii a?ae /ano aeieeiaiiy i?ci?o aanoic?a, ii 3 ae?aaea 4 ?ace ia aeiao i?ioyaii 2-3 oeaei?a ciaoiaeaeaiiy aaa?oii? a oiiaao noaoe?iia?o oa i?ney aeienee i?ae iaaeyaeii e?ea??a ae?ii/i? eiinoeueoaoe??. Aoaeoeai?noue e?eoaaiiy, ni?yiiaaiiai ia iie?auaiiy caaaeueii? i?e?ioee?eoeyoe??, ioe?ithaaee iiceoeaiith /e iaaaoeaiith ee?i?/iith aeeiai?eith ia?aa?ao aaa?oiino? ia oii? e?eoaaiiy, aeaieo eaai?aoi?ieo aeine?aeaeaiue, aeaieo aea/aiiy i?e?ioee?eoeyoe?? aoeueaa?iiai eooa iea c ianooiiith ?? ii?oiiao???th oa aeaieie ?aieia?/iiai noaoono aaa?oieo. A a?oi?, aea ae?iee io?eioaaee cai?iiiiiaaio iaie noaio, i?ney eo?no i?io?eaeoe/iiai e?eoaaiiy i?e i?aaeeaiin?? eaaeiai nooiaiy a 34-35 oeae aaa?oiino? an? aaa?oi? aei ?iae?a aoee aeienai? ?c noaoe?iia?o /a?ac a?aenooi?noue o ieo neiioii?a i?ciueiai aanoico. I?e oeueiio caaaeueia o?eaae?noue e?eoaaiiy o ieo noaiiaeea a na?aaeiueiio 9,0±0,9 aei?a. O aaa?oieo ye? ia io?eioaaee aiaaicei, caaaeueia o?eaae?noue e?eoaaiiy neeaaeaea 13,1±0,9 aei?a. O aaa?oieo c i?aaeeaiin??th na?aaeiueiai nooiaith, ye? io?eioaaee cai?iiiiiaaio iaie oa?ai?th, na?aaei?e oa?i?i e?eoaaiiy neeaaeaa 11,2±0,7 aei?a, ui a??ia?aeii ieae/a ii??aiyii c oa?i?iii e?eoaaiiy i?e i?aaeeaiin?? na?aaeiueiai nooiaiy i?e caaaeueiii?eeiyoiio e?eoaaii?. Aei ?ic?iaeaeaiiy iaeaea o an?o oeeo aaa?oieo aoee iiai?noth e?ea?aeiaai? iciaee i?ciueiai aanoico, iaeiae aiie ciaoiaeeeenue o noaoe?iia?? aei iiiaioo iieia?a, ? oa?i?i aaa?oiino?, o yeiio i?iaiaeeeinue ?ic?iaeaeaiiy, a oe?e a?oi? noaiiaea 38,5±1,3 oeae. O an?o ae?iie oe??? a?oie i?iaaaeaii i?ia?aiiaai? iieiae oeyoii canoinoaaiiy aeiiieiaiai? i?aeaioiaee ? aaaeaiiy iieia?a i?inoaaeaiaeeiiaeie i?aia?aoaie A2. ?c noaoe?iia?o ae?iee aeacaii? a?oie aoee aeienai? ?c iiai?noth noaa?e?ciaaieie ia?aiao?aie aaiiaeeiai?ee ? iaoaaie?cio. O aaa?oieo c i?aaeeaiin??th na?aaeiueiai nooiaiy, ye? io?eioaaee caaaeueiii?eeiyoo oa?ai?th, na?aaei?e oa?i?i e?eoaaiiy neeaaeaa 14,2±1,1 aeiy, iaeiae e?ea?aeoaaoe neiioiiaoeeo caoai?thaaiiy ia aaeaeiny, ? aiie aoee ?ic?iaeaeai? aeino?ieiai. Aoaeoeai?noue i?iaaaeaiiai e?eoaaiiy ie ioe?ithaaee oaeiae ca aeiiiiiaith ?iaeaeno i?e?ioee?eoeyoe??. O ae?iie c i?aaeeaiin?ath eaaeiai nooiaiy i?e canoinoaaii? caaaeueii-i?eeiyoi? oa?ai?? ?iaeaen i?e?ioee?eoeyoe?? iie?aueany ia 2,8±0,3 aaee, a i?e canoinoaaii? aiaaiceio ia 7,6±0,4 aae?a. I?e i?aaeeaiin?? na?aaeiueiai nooiaiy - ?iaeaen i?e?ioee?eoeyoe?? a?aeiia?aeii iie?aueany ia 6,5±0,7 ? 12,9±0,5 aae?a. Aoaeoeai?noue e?eoaaiiy aeiaaaeaii oaeiae iie?auaiiyi a?io?i?/ieo ? ?aieia?/ieo iieaciee?a aaa?oieo ae?iie aein-e?aeaeoaaieo a?oi oa noaoenoe/ii a??ia?aeiei ciaioaiiyi o?eaaeino? ia?aaoaaiiy aaa?oieo o noaoe?iia?? ia 1,5-2 aei?. Anoaiiaeaii iie?auaiiy noaio iiaiia?iaeaeaieo a na?aaeiueiio ia 2 aaee ca oeaeith Aiaa? oa ciaioaiiy caaaeueii? e?iaiao?aoe ia 70-100 ie. Io?eiaio cia/io aoaeoeai?noue e?eoaaiiy i?ci?o aanoic?a aiceiaie ie iia’yco?ii c a?eueo iiaiei iaoiaaiaoe/ii iaa?oioiaaiei e?eoaaiiyi ?, aiane?aeie oeueiai, oaeaeoith ei?aeoe??th ia?aiao??a aiiainoaco, yeee caaacia/o? aeeoo?ae?yeuei?noue iaoa?einueeiai i?aai?cio. AENIIAEE 1. Ia i?aenoaa? aiae?co 4800 ?noi??e iieia?a (ca /ioe?e ?iee o iieiaiaiio aoaeeieo) i?ci? aanoice o caei?iaeo ae?iie iaee i?noea o 6,4% aeiaaee?a. 2. O ae?iie c i?ci?i aanoicii i?e?inoaeeii? ?aaeoe?? a aeeiai?oe? aaa?oiino? i?iyaeythoueny i?ia?anoth/ei ciaioaiiyi ae?aiao?o noaeei aeinoaaee oa iai?io, aeeeyoaoe??th a?aeoiaey/eo eaioetha?a, ciaioaiiyi /enea ooieoe?iioth/eo eai?ey??a, ui coiiaeth? ciaioaiiy e?iaiia?ao ? aa?aaaoe?th oi?iaieo aeaiaio?a e?ia?. 3. Ii?ooaiiy ?aieia?/ieo aeanoeainoae e?ia? o aaa?oieo c i?ci?i aanoicii iineeththoueny c ia?inoaiiyi oyaeeino? caoai?thaaiiy ? oa?aeoa?ecothoueny i?e i?aaeeaiin?? na?aaeiueiai ? oyaeeiai nooiaiy nei?i/aiiyi /ano cai?oaiiy e?ia? ca ?aooiie oaeaeoiai ii/aoeo, cieaeaiiyi /ano ?aeaeueoeeo?eaoe?? ieacie, ca?eueoaiiyi i?io?iia?iiaiai ?iaeaeno, ciaioaiiyi e?eueeino? o?iiaioeeo?a oa iiceoeaiith ?aaeoe??th ia o?a??iiaai A. 4. Na?aaeiy ioe?iea i?e?ioee?eoeyoi?ieo ii?ooaiue (ca iiaeeo?eiaaiith oeaeith) neeaaeaea i?e i?aaeeaiin?? eaaeiai nooiaiy 22,6±5,2 aaea, i?e i?aaeeaiin?? na?aaeiueiai nooiaiy oyaeeino? 31,5±8,4 aaea, i?e i?aaeeaiin?? oyaeeiai nooiaiy 40,8±9,7 aaea, ui aeaei ciiao ia’?eoeai?oa ioe?ieoe noai i?e?ioee?eoeyoe?? ? oaeei /eiii ?aeiiaiaeoaaoe ?? ye eiio?ieue ca ?icaeoeii i?ciueiai aanoico oa aoaeoeai?noth e?eoaaiiy. 5. O aaa?oieo c i?ci?ie aanoicaie a?aeaoaathoueny cia/i? ai?iiiaeuei? ci?ie, ye? oa?aeoa?ecothoueny ca?eueoaiiyi ai?noo ano?aae?ieo, ano??ieo, ei?oecieo, o??aio?ii?io, a oaeiae a??ia?aeiei cieaeaiiyi ieaoeaioa?iiai eaeoiaaio, o?eeiaeo??ii?io oa o??ieneio ii??aiyii c? caei?iaeie aaa?oieie. 6. Niiaoioeiieia?y aaa?oieo c i?ci?ie aanoicaie oa?aeoa?eco?oueny ciaioaiiyi L-eiiiiiaioo ? c?inoaiiyi F-eiiiiiaioo, ui iiaea aooe aeei?enoaii aeey eiiieaeniiai i?iaiicoaaiiy cacia/aii? iaoieia??. 7. Iaeneiaeueia /anoioa o?aieyiiy anioe?aoe?e a?eo?ioeeoa?ieo aioeaai?a e?ia? o aaa?oieo c i?ci?ie aanoicaie ca 5-oe eiiiiiaioiith nenoaiith oaiioei?/ii oa?aeoa?eco?oueny: 0(I) IN ?(+) Rh(+) I? 2-1 - 13,9%; 0(I) IN ?(+) Rh(+) I? 2-2 - 7,8%; I(I) I ?(+) Rh (+) I? 2-2 - 6,1%; A(???) IN ?(+) Rh (+) I? 2-1 - 3,0%, ui iiaea aooe aeei?enoaii i?e i?iaiicoaaii? i?ci?o aanoic?a. 8. Ia iniia? aea/aiiy niiaoioeio, anioe?aoe?e a?eo?ioeeoa?ieo aioeaai?a, aiaei- oa aeciaai?? aeae?eai? i?iaiinoe/i? e?eoa???, ye? iiaeooue aooe aeei?enoai? aeey i?iaiicoaaiiy oa nai?/anii? i?io?eaeoeee aeieeiaiiy i?ci?o aanoic?a o oeeo ae?iie. 9. ?ic?iaeaiee ia i?aenoaa? aeaieo eii’thieoeaaeueii? a?ii?e?ineii??, ai?iiiaeueiiai i?io?eth, niiaoioeiieia?/ieo iciae aeai?eoi i?iaiicoaaiiy aeicaiey? ia?aaeaa/eoe ?icaeoie i?ciueiai aanoico a eiaeiiio eiie?aoiiio aeiaaeeo aaa?oiino?. 10. Aeeth/aiiy nenoaiii? aiceiioa?ai?? a eiiieaenia i?io?eaeoe/ia e?eoaaiiy i?ci?o aanoic?a ni?ey? iie?ioaiith ooieoe?? i?e?ioee?eoeyoi?iiai ?onea ca ?aooiie ?? aioeaa?aaaoe?eieo, i?ioeiaa?yeiaeo oa o?a?eiie?oe/ieo aeanoeainoae. 11. Oaeineiiaeaiee eiiieaen e?eoaaeueii-i?io?eaeoe/ieo caoiae?a ?c canoinoaaiiyi nenoaiii? aiceiioa?ai?? aoa aoaeoeaiei o 81,3% aeiaaee?a, ui aeicaieeei cieceoe oa?i?i e?eoaaiiy ia 1,5-2 aei?, iie?aueoe noai iiaiia?iaeaeaieo ca oeaeith Aiaa? ia 2 aaee, cieceoe e?iaiao?aoo ia 70-100 ie (?<0,001), ciaioeoe ia?eiaoaeueio nia?oi?noue a 1,5 ?ace. I?AEOE*I? ?AEIIAIAeAOe?? 1. Aeei?enoaiiy iiaeeo?eiaaii? oeaee a ??cieo no?ieao aaa?oiino? c aecia/aiiyi i?e?ioee?eoeyoi?ieo ii?ooaiue iaoiaeii eii’thieoeaaeueii? a?ii?e?ineii?? oa ?aieia?/ieo ci?i, aeicaiey? i?iaiicoaaoe i?ci?e aanoic ( a ae?aiacii? a?ae 6 aei II aae?a) oa ae??ooaaoe ieoaiiy i?i aeioe?euei?noue i?ieiiaoaaiiy aaa?oiino? o ae?iie c oyaeeeie oi?iaie (e?euee?noue aae?a ia?aaeuo? 35). 2. Canoinoaaiiy iiai? iaoiaeeee ee?i?ei-iaoaiaoe/iiai ? ?iaeea?aeoaeueiiai i?iaiicoaaiiy i?ciueiai aanoico, yea a?aoiao? aeai? niiaoioeio ( ciaioaiiy L-eiiiiiaioo oa ca?eueoaiiy F-eiiiiiaioo ), niieo/aiiy anioe?aoe?e a?eo?ioeeoa?ieo aioeaai?a e?ia? ca 5-oe eiiiiiaioiith nenoaiith, yea oaiioei?/ii oa?aeoa?eco?oueny; 0(I) IN ?(+) Rh(+) I? 2-1-13,9%; 0(I) IN ?(+) Rh(+) I? 2-2 - 7,8%; 0(I) I ?(+) Rh (+) I? 2-2 - 6,1% (EI=0,31); A(???) IN ?(+) Rh (+) I? 2-? 3,0%), aieea aiaeiaai?? (87,1%), ?iaeea?aeoaeueiee ai?iiiaeueiee i?io?eue ( i?aeaeuaiiy ??aith ano?aae?ieo, ano??ieo, ei?oecieo ? o??aio?iiiiai ai?iiio oa cieaeaiiy ieaoeaioa?iiai eaeoiaaio, o?eeiaeo??ii?io ? o??ieneio), ?acoeueoaoe eii’thieoeaaeueii? a?ii?e?ineii?? (ioe?iea a?ae 6 aei 30 aae?a), aeicaiey? ae?aaiinooaaoe oa aecia/eoe nooi?iue oyaeeino? i?ciueiai aanoico. 3. Aeey i?io?eaeoe/iiai e?eoaaiiy i?ciueiai aanoico ?aeiiaiaeo?oueny canoiniaoaaoe ianooiiee eiiieaen i?aia?ao?a: aiaaicei ii 3 ae?aaea 3 ?ace a aeaiue, o?aioae ii 200 ia, aoo?ee?i ii 0,12, eo?aio?e ii 0,025, aeooai?iiao eeneioo ii 0,25 2 ?ace a aeaiue, a?oai?i A ii 100 ia 1 ?ac a aeaiue, a?oai?i A6 ii 2 ie a/i 1 ?ac a aeaiue i?ioyaii aeaio oeaei?a o 20-22, 26-28, 32-34 oeaei? aaa?oiino?. 4. ?acoeueoaoe iieaciee?a ai?iiiaeueiiai i?io?eth aaa?oieo, ye? oa?aeoa?ecothoueny ca?eueoaiiyi i?e i?aaeeaiin?? eaaeiai nooiaith ai?noo ano?aae?ieo aei 62,49±0,99 iiieue/e; ano??ieo aei 148,35±2,58 iiieue/e; ei?oecieo aei 1731,19±20,41 iiieue/e; o??aio?ii?io 2,92±0,62 iiieue/e, a i?e i?aaeeaiin?? na?aaeiueiai ? oyaeeiai nooiaith - 69,86±0,28iiieue/e; 157,54±0,14 iiieue/e; 1788,72±17,96 iiieue/e ? 3,02±0,82 iiieue/e a?aeiia?aeii, a oaeiae a??ia?aeiei cieaeaiiyi i?e i?aaeeaiin?? eaaeiai nooiaith ieaoeaioa?iiai eaeoiaaio aei 192,41±4,9 iiieue/e; o?eeiaeo??ii?io aei 1,58±0,32 iiieue/e; o??ieneio aei 201,95±5,49 iiieue/e , a i?e i?aaeeaiin?? na?aaeiueiai oa oyaeeiai nooiaith a?aeiia?aeii aei 179,68±4,61 iiieue/e; 1,06±0,15 iiieue/e; 164,42±7,50 iiieue/e, iiaeooue aooe aeei?enoai? ye aeiiii?aei?, o ae?aaiinoeoe? oa i?iaiicoaaii? iaoieia??, ui aea/a?oueny. NIENIE IIOAE?EIAAIEO ?IA?O CA OAIITH AeENA?OAOe?? 1. No/ani? aniaeoe iaaeiiooaaiiy i?e i?ci?o aanoicao //Iaaeiiooaaiiy aaa?oiino?. Ca??iee iaoeiaeo i?aoeue, Ee?a, - 1997.- N.167-168. 2. Iaa?oiooaaiiy oa?i?i?a i?io?eaeoe/iiai e?eoaaiiy ? iaoiae?a ?ic?iaeaeaiiy ae?iie c ii?ooaiiyie i?e?ioee?eoeyoe?? i?e i?ci?o aanoicao //Ca??iee iaoeiaeo i?aoeue anioe?aoe?? aeooa??a-a?iaeieia?a Oe?a?ie.- N?ioa?iiieue 1998.- N. 464-465. 3. No?oeoo?a aeooa?nueeeo oneeaaeiaiue o ae?iie c i?ci?ie aanoicaie aaa?oieo / A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1999.- O. 1, ?1.- N. 86-87. 4. Aeina?ae canoinoaaiiy nenoaiieo aiceiieo i?aia?ao?a a eiiieaeniiio e?eoaaii? i?ci?o aanoic?a //A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1999.-O.2, ?1.- N.122-123. 5. Oeyoe i?iaiicoaaiiy ? i?io?eaeoeee i?ciueiai aanoico //Iaae?ao??y, aeooa?noai ? a?iaeieia?y.- 1991.-O.2, ?1.- N. 45-46. (Ni?aaaoi?e: Ieoaeue/oe I.A., Aaeno?oe A.I.) 6. Aeaye? iaoiaee i?iaiicoaaiiy i?ciueiai aanoico aaa?oieo //A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1997.- O.1, ?1.- N.52-53. 7. Noai nenoaie i?e?ioee?eoeyoe?? i?e i?ci?o aanoicao //Iaae?ao??y, aeooa?noai ? a?iaeieia?y.- 1998.- ?3.- N. 61-63. 8. Iaoia?noieia?/i? ci?ie a iaoeao aaa?oieo naiie uo??a i?ae ae??th a?a?aoe?eiiai oaeoi?a //A?niee ii?oieia??.-1998.- O.4, ?1.- N.75. (Ni?aaaoi?e: Eiiueeia Ae.A., AEoe N.?.) 9. Ee?i?/ia cia/aiiy aecia/aiiy o?ioiaeanoe/iiai aaoa-ae?eii?ioa?io a ioe?ioe? noaio oaoi-ieaoeaioa?iiai eiiieaeno //Iaae?ao??y, aeooa?noai ? a?iaeieia?y.- 1993.-?3.- N.38-39. (Ni?aaaoi?e: Iaoa?ao?cueea A.O., AEoe N.?.) 10. Iiaeaethaaiiy ?icaeoeo i?ci?o aanoic?a iaoiaeii aeene?ei?iaioiiai aiae?co a aeooa?nuee?e ee?i?oe? // A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1998.-O.2, ?2.- N.503-504. (Ni?aaaoi?e: A?aeoaoeueeee I.A., A?eai?aiei A.I.) 11. Canoinoaaiiy aiaaiceio o aaa?oieo c ??cieie nooiaiyie iaee??iiy // Iaae?ao??y, aeooa?noai ? a?iaeieia?y.- 1998.- ?6.- N .116-118. (Ni?aaaoi?e: Aiaeeaanueea I.A., AEoe N.?. ) 12. Aei?iaeiaay iiaeaioiaea aeaiuei n iicaeieie aanoicaie // A?a/aaiia aeaei,- 1999.- ?2- N. 109-110. (Ni?aaaoi?e: AEoe N.E., *a/oaa N. A.) 13. Nenoaiia aiceiioa?ai?y o aaa?oieo c aa?eeiciith oai?iaith // Oa?iaeieia?/iee a?niee. - 1999. - ?2.- N. 54-55. (Ni?aaaoi?e: AEoe N.?., Oaa/oe O.A.) 14. Aeaye? aniaeoe ia?aa?ao aaa?oiino? oa iieia?a o ae?iie c ii?aeiaiiyi aiai?? aaa?oieo oa aanoicii // A?a/aaiia aeaei.- 1999,- ?3 , N. 132-133(Ni?aaaoi?e: AEoe N.?., I?ioeaiei I.I.) 15. Ei?aeyoeai? ca’ycee i?ae oaeoi?aie niiaoioeio oa o??ai?aeiith ooieoe??th i?aai?cio i?e aeieeiaii? ? ?icaeoeo i?ciueiai aanoico //A?niee ii?oieia??.- 1999, o. 5,- ?1,- N. 84-95 (Ni?aaaoi?e: A?aeoaoeueeee A.A., A?eai?aiei A.I.) 16. Niin?a e?eoaaiiy i?ci?o aanoic?a //Iaoaio ia aeiao?ae ?98020808 a?ae 13.10.98 17. Aeeaaiinoeea, i?ioeeaeoeea e ea/aiea caaea?aeee ?acaeoey (aeiio?ioee) ieiaea //Iaoiaee/aneea ?aeiiaiaeaoeee.-?IE-91, ?5 Eeaa,- 1992.- 26 n. (Ni?aaaoi?e: Ieoaeeaiei A.O., Noaiaieianeay A. E. , Aaiaeee A. O. ) 18. Canoinoaaiiy aiceiieo i?aia?ao?a i?e aeayeeo aeaeao aeooa?nueei? iaoieia?? //II Oe?a?inueea i?aeia?iaeia eiioa?aioe?y c i?aei. o/anoth “Aeooaeuei? i?iaeaie ee?i?/ii? oa?iaeieia??”,- A?iieoey 6-8 aeiaoiy 1998 ?., N. 233-235 (Ni?aaaoi?e: Aiaeeaanueea I.A., AEoe N.?.) 19. Niiaoioei ? i?ci?e aanoic //Oace aeiiia?aeae O c’?caeo aeooa??a-a?iaeieia?a Oe?a?ie.- Iaeana, 1996,- N. 78-79 20. Eiinoeoooeeiiaeueiua iniaaiiinoe i?e caaea?aeea ?acaeoey ieiaea //Aeooaeueiua aii?inu aeooa?noaa e aeiaeieiaee. THaeeae OOAa,- Aeiiaoee 1995. 21. Eiinoeoooe?ei? iniaeeaino? aaa?oieo ae?iie c iaee??iiyi //Iaoa??aee i?aeia?iaeiiai neiiic?oio “I?eioeeie i?iii?oe?? neiao???, no?oeoo?ii? aa?iii?? oa iaoaiaoe/iiai iiaeaethaaiiy a ii?oieia??.- A?iieoey. 1997. - N .70-71 (Ni?aaaoi?e: Aiaeeaanueea I.A., AEoe N.?.) 22. Ai?no ai?iii?a a?iio?ca?ii-o??ai?aeii? nenoaie a e?ia? aaa?oieo c i?ci?ie aanoicaie // E?ea?nueea ni?aaa.- 1999.- ? 5.- N. 111-112. 23. Modern aspects of etiopathogenesis and treatment of EPH gestosis // Indian Journal of Community Medicine.- 1999.- Vol XXIV.- N2.- P. 86-87. (Seema Munjal, I.S.Zhuck) 24. Iniaeeaino? aaaeaiiy aaa?oiino? oa iieia?a o ae?iie c i?ci?i aanoicii // A?niee anioe?aoe?? aeooa??a-a?iaeieia?a Oe?a?ie - Ee?a, 1999.- ? 2.- N. 55-58. AIIOAOe?ss Eai?inueeee A.A. I?iaiicoaaiiy, i?io?eaeoeea oa e?eoaaiiy i?ci?o aanoic?a , (ee?i?ei-eaai?aoi?ia oa aio?iiiaaiaoe/ia aeine?aeaeaiiy).- ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.01 - aeooa?noai ? a?iaeieia?y.-Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey, 1999. I?iaaaeaii eiiieaeni? aeine?aeaeaiiy o aaa?oieo ae?iie c ??cieie nooiaiyie oyaeeino? i?ci?o aanoic?a oeyoii aea/aiiy ai?iiiaeueiiai noaoono, niiaoioeiieia?/ieo iciae, a?eo?ioeeoa?ieo aioeaai?a e?ia? ? ?o annioe?aoe?e, noaio i?e?ioee?eoeyoi?iiai ?onea, aieeao aiaei- ? aeciaai??. I?e oe?e iaoieia?? aoei anoaiiaeaii cia/i? ci?ie iieaciee?a ano??ieo, ano?aae?ieo, ieaoeaioa?iiai eaeoiaaio, i?ieaeoeio, ei?oecieo, ai?iii?a ueoiaeaeii? caeice. Anoaiiaeaii iniaeeaino? niiaoioeio ae?iie aeine?aeaeoaaieo a?oi oa aieea aiaei- oa aeciaai?? ia aeieeiaiiy i?ci?o aanoic?a. Aoei oaeiae anoaiiaeaii ci?ie a i?e?ioee?eoeyoi?iiio ?one? aaa?oieo. C o?aooaaiiyi ?acoeueoao?a ai?iiiaeueieo, ?ino?oiaioaeueieo oa aaiaoe/ieo iaoiae?a aeine?aeaeaiiy aoei ?ic?iaeaii ?iaeea?aeoaeueiee iaoiae iiaeaethaaiiy ? i?iaiicoaaiiy i?ci?o aanoic?a, yeee aeicaieea c aenieei nooiaiai oi/iino? ia?aaeaa/aoe ?acoeueoao aaa?oiino? ? ?iae?a. C iaoith e?eoaaiiy ? i?io?eaeoeee i?ciueiai aanoico cai?iiiiiaaii iniaenoee iaoiae c eiiieaeniei aeei?enoaiiyi nenoaiieo aiceiieo i?aia?ao?a (aiaaicei). Eiai canoinoaaiiy aeicaieeei iie?aueoe ee?i?/i? ? eaai?aoi?i? iieacieee noaio iaoa?? ? ieiaea, ciaioeoe e?euee?noue oneeaaeiaiue. Eeth/ia? neiaa: aaa?oi?noue, i?ci? aanoice, nenoaiia aiceiioa?ai?y, niiaoioeiieia?y, ii?ooaiiy i?e?ioee?eoeyoe??, a?eo?ioeeoa?i? aioeaaie e?ia?. AIIIOAOeEss Eaieineee A.A. I?iaiice?iaaiea, i?ioeeaeoeea e ea/aiea iicaeieo aanoicia (eeeieei-eaai?aoi?iia e aio?iiiaaiaoe/aneia enneaaeiaaiea). Aeenna?oaoeey ia nieneaiea o/aiie noaiaie aeieoi?a iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.01- aeooa?noai e aeiaeieiaey.- Iaoeeiiaeueiue iaaeeoeeineee oieaa?neoao ei. A.A.Aiaiiieueoea, 1999. Caueuaaony aeena?oaoeeiiiay ?aaioa e 16 iao/iuo noaoae, eioi?ua niaea?aeao naaaeaiey ia iniaaiiinoyo niiaoioeia, annioeeaoeeyo aioeaaiia e?iae ii 5-e eiiiiiaioiie nenoaia, iieacaoaeyo ai?iiiia i?iaanoa?iia, yno?aaeeiea, yno?eiea, i?ieaeoeia, ieaoeaioa?iiai eaeoiaaia, ei?oeciea, oe?aio?iiiiai, O3, O4 ai?iiiia), iniaaiiinoyo iee?ioee?eoeyoi?iiai ?onea o aa?aiaiiuo n ?aciuie noaiaiyie oyaeanoe iicaeieo aanoicia e caei?iauo aa?aiaiiuo. Onoaiiaeaii, /oi iicaeiea aanoicu /aua eiatho ianoi o aeaiuei n iaoaeiaeaoai?eoaeueiui iaoa?eaeueiui iaania/aieai, n iannie oaea aieaa 70 ea, n ainiaeeoaeueiuie caaieaaaieyie iaoee e i?eaeaoeia a aiaiiaca, n naiii?iecaieueiui i?a?uaaieai aa?aiaiiinoe. Ai a?aiy aa?aiaiiinoe o aeaiuei n iicaeieie aanoicaie /aua eiaea ianoi aioo?eoo?iaiay aeiieney ieiaea, aiaiey, a ai a?aiy ?iaeia - anoeeney iiai?iaeaeaiiuo, iia?aoeaiua aiaoaoaeuenoaa, iinea?iaeiaua ainiaeeoaeueiua caaieaaaiey, aieueoay e?iaiiioa?y. Eco/aia ?ieue ianeaaenoaaiiuo oaeoi?ia (yiaei- e yeciaaiee, niiaoioeia, y?eo?ioeeoa?iuo aioeaaiia e?iae) a iaoiaaiaca iicaeieo aanoicia e onoaiiaeaii, /oi iicaeiea aanoicu /aua eiatho ianoi o aeaiuei io yiaeiaaiiuo a?aeia, /oi naeaeaoaeuenoaoao i aaniiii aeeaaea ianeaaenoaaiiinoe a ?acaeoea yoie iaoieiaee. Niiaoioeiieiaey aeaiuei n iicaeieie aanoicaie oa?aeoa?ecoaony oiaiueoaieai L-eiiiiiaioa e oaaee/aieai F-eiiiiiaioa, onoaiiaeaia oaeaea iaeneiaeueiay /anoioa ano?a/aaiinoe ii?aaeaeaiiuo annioeeaoeee y?eo?ioeeoa?iuo aioeaaiia e?iae ii 5-e eiiiiiaioiie nenoaia. Iee?ininoaeenoua eciaiaiey o aa?aiaiiuo n iicaeieie aanoicaie i?iyaeythony i?ia?anne?othuei oiaiueoaieai aeeaiao?a ninoaeia aeinoaaee e iaiaia, aeeeyoaoeeae ioaiaeyueo caaiueaa, oiaiueoaieai /enea ooieoeeiie?othueo eaieeey?ia, /oi i?eaiaeeo e oiaiueoaieth e?iaiia?auaiey e aa?aaaoeee oi?iaiiuo yeaiaioia e?iae. Ia?ooaiey ?aieiae/aneeo naienoa e?iae o aa?aiaiiuo n iicaeieie aanoicaie oneeeaathony n ia?anoaieai oyaeanoe i?ioeanna e oa?aeoa?ecoaony oei?i/aieai a?aiaie naa?ouaaiey e?iae ca n/ao oiaiueoaiey a?aiaie ?aeaeueoeeoeeaoeee ieaciu, oaaee/aiey i?io?iiaeiiaiai eiaeaena, oiaiueoaiey eiee/anoaa o?iiaioeeoia e iieiaeeoaeueiie ?aaeoeeae ia oea?eiiaai A. Aeey aieaa oi/iie aeeaaiinoeee iee?ioee?eoeyoi?iuo ia?ooaiee o aa?aiaiiuo n iicaeieie aanoicaie iiaeeoeoee?iaaia oeaea ioeaiee iee?ioee?eoeyoi?iuo ia?ooaiee iaoi/ii-ieaoeaioa?iiai eiiieaena ca n/ao aeaiiuo aaiieiaaoeyoeeiiiuo iieacaoaeae. Eiaeaen iee?ioee?eoeyoeee o aa?aiaiiuo n i?ayeeaiineae eaaeie noaiaie ninoaaeye 22,6±5,2 aaea, i?e i?ayeeaiinee n?aaeiae noaiaie oyaeanoe 31,5±8,4 aaea, i?e i?ayeeaiinee oyaeaeie noaiaie 40,8±9,7 aaea, /oi eiaao aunieia i?iaiinoe/aneia cia/aiea (96-98%) i?e iiaeaee?iaaiee aeaiiie iaoieiaee. O aa?aiaiiuo n iicaeieie aanoicaie i?ienoiaeyo cia/eoaeueiua ai?iiiaeueiua ia?ooaiey, eioi?ua oa?aeoa?ecothony oaaee/aieai niaea?aeaiey yno?aaeeiea, yno?eiea, ei?oeciea, oe?aio?iieia, a oaeaea aeinoiaa?iui nieaeaieai ieaoeaioa?iiai eaeoiaaia, o?eeiaeoe?iieia e oe?ieneia. Ia iniiaa eco/aiey niiaoioeiia, annioeeaoeee y?eo?ioeeoa?iuo aioeaaiia e?iae, yiaei- e yeciaaiee auaeaeaiu i?iaiinoe/aneea e?eoa?ee, eioi?ua iiaoo auoue eniieueciaaiu aeey naiaa?aiaiiiai i?iaiice?iaaiey e i?ioeeaeoeee iicaeieo aanoicia o aeaiuei a?oii ?enea. ?ac?aaioaiiue ia iniiaa aeaiiuo aeiiee?ineiiee eiiuthieoeau, niiaoioeiieiae/aneeo i?eciaeia, annioeeaoeee aioeaaiia e?iae, ai?iiiaeueiiai i?ioeey aeai?eoi i?iaiice?iaaiey iicaieyao i?aaeaeaeaoue aicieeiiaaiea iicaeieo aanoicia a eaaeaeii eiie?aoiii neo/aa. N oeaeueth i?ioeeaeoeee e ea/aiey ia?ooaiee iee?ioee?eoeyoeee o aeaiuei n ?aciuie noaiaiyie oyaeanoe iicaeieo aanoicia ia oiia iauai?eiyoiai ea/aiey iacia/aee nenoaiiue yiceiiue i?aia?ao - aiayicei, eioi?ue aeaaeaao i?ioeaiioa/iui, eiioiiiiaeoee?othuei, aoi?e/ii aiaeaace?othuei yooaeoii. Aai i?eiaiaiea i?eaiaeeo e oeo/oaieth ?aieiae/aneeo naienoa e?iae ca n/ao ii?iaeecaoeee aa ayceinoe e iee?ioee?eoeyoeee a nayce n ?ac?ooaieai ia?aciaaaoeony o?iiaia. Oniaa?oainoaiaaiiue eiiieaen ea/aaii-i?ioeeaeoe/aneeo ia?ii?eyoee i?e iicaeieo aanoicao aue yooaeoeaiui a 81,3% neo/aaa, /oi iicaieeei oiaiueoeoue a?aiy ea/aiey aa?aiaiiuo, oeo/oeoue ninoiyiea iiai?iaeaeaiiiai i?e ?iaeaeaiee, nieceoue e?iaiiioa?th e ia?eiaoaeueioth nia?oiinoue. Eeth/aaua neiaa: aa?aiaiiinoue, iicaeiee aanoic, nenoaiiay yiceiioa?aiey, niiaoioeiieiaey, iee?ioee?eoeyoi?iua ia?ooaiey, aaiaoe/aneea ia?ea?u e?iae. SUMMARY Kaminsky V. V. The prognosis, prophylactic and treatment of OPH-gestosis (clinical and laboratory and somatotypic investigation). Thesis for scintific degree of doctor of medical sciences in speciality 14.01.01. - Obstetrics and Gynecoloqy of National medical univercity n.a. A.A. Bogomoltsa, 1999. The complex researches at the pregnant women with the factors of occurence of OPH-gestosis are carried out by study of gormone status, somatotype attributes, erythrocyte antigenes of blood and their assotiations, condition of microcirculation influence of endo- and exogamii. At OPH-gestosis the presence of the expressed changes in parameters of estriol, estradiol, placental lactogen, prolactin, cortizol, thyriod hormone was established changes in microcirculation also were marced. In view of genetic methods of reseach, the individual method of modeling and forecasting of OPH-gestosis was developed; it has allowed with a high degree of accuracy to previde outcome of pregnancy and delivery. With the purpose of treatment and preventive maintenance the own method with the use of system enzyme preparations, in particular, wobenzym is offered. The application it has allowed to improve clinical and laboratory parameters of a condition of the mother and fetus. Key words: pregnancy, OPH-gestosis, system enzymtherapy, somatotypology, disorders of microcirculation, genetic markers of blood.

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