?INOEOOO IAAe?AO???, AEOOA?NOAA OA A?IAEIEIA??

AEAAeAI?? IAAeE*IEO IAOE OE?A?IE

EI?IAOeUeEA AEEA A?EAI??AIA

OAeE 618.17.171-08-089-084.

I?IAIICOAAIIss, I?IO?EAEOEEA ? IAA?OIOOAAIIss

IAOIAAIAOE*II? OA?AI?? O AE?IIE C II?AeIAIEIE

OI?IAIE IAIE?AeIINO?

14.01.01 — aeooa?noai ? a?iaeieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Ee?a — 1998

Aeena?oaoe?y ? ?oeiienii

?iaioa aeeiiaia a ?inoeooo? iaae?ao???, aeooa?noaa oa a?iaeieia?? AII
Oe?a?ie.

Iaoeia? eiinoeueoaioe:

aeieoi? iaaee/ieo iaoe, i?ioani?

?AAITHOA E?Ae?ss ?AAI?AIA

?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie

caa?aeoaa/ a?aeae?eaiiy ?aaa?e?oaoe?? ?ai?iaeoeoeaii? ooieoe?? ae?iie

aeieoi? iaaee/ieo iaoe, i?ioani?

*A?IEOIA A?EOI? IAAEIAE*

?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie

caa?aeoaa/ eaai?aoi??? ?ioiieia??

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani?, /eai-ei?aniiiaeaio AII Oe?a?ie

NOAIAIE?ANUeEA AAEEIA EINOssIOEI?AIA

Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey (i.Ee?a),
IIC Oe?a?ie

i?ioani? eaoaae?e aeooa?noaa oa a?iaeieia?? N1

aeieoi? iaaee/ieo iaoe, i?ioani?

O?AI*OE AIAOIE?E THOEIIAE*

Oa?iii?euenueea Aea?aeaaia iaaee/ia aeaaeai?y ?i. ?.ss.Ai?aa/aanueeiai
IIC Oe?a?ie

i?ioani? eaoaae?e aeooa?noaa ? a?iaeieia?? iaaee/iiai oaeoeueoaoo

aeieoi? iaaee/ieo iaoe, i?ioani?

Ae?AIEE AAI?A?E IEEIEAEIAE*

?inoeooo o?ieia?? ? iao?ieia?? AII Oe?a?ie

caa?aeoaa/ eaai?aoi??? ?ioiieia??

I?ia?aeia onoaiiaa — Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe
?i. I.E.Ooieea IIC Oe?a?ie, eaoaae?a aeooa?noaa oa a?iaeeia?? ?1

Caoeno a?aeaoaeaoueny «9» eenoiiaaea 1998 ?ieo ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee ii caoenoo aeena?oaoe?e ia caeiaoooy
iaoeiaiai nooiaiy aeieoi?a iaoe ca niaoe?aeueiinoyie «Iaae?ao??y»,
«Aeooa?noai ? a?iaeieia?y» (Ae 26.553.01) i?e ?inoeooo? iaae?ao???,
aeooa?noaa oa a?iaeieia?? AII Oe?a?ie (252050, i.Ee?a, aoe.
Iaio?euenueeiai, 8).

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? ?inoeoooo iaae?ao???,
aeooa?noaa oa a?iaeieia?? AII Oe?a?ie ( 252050, i.Ee?a,
aoe.Iaio?euenueeiai, 8).

Aaoi?aoa?ao ?ic?neaiee «16» aeiaoiy 1998 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Eaaoi?ia E.A.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie. ?ai?iaeoeoeaia caei?ia’y aecia/athoue ye
noai, a yeiio ?ai?iaeoeoeaiee i?ioean cae?enith?oueny o iiaiiio
o?ce/iiio, ineo?/iiio, nioe?aeueiiio aeaaiiieo//?. Iaeiei ?c ae?eiaeo
oaeoi??a, yeee a?ae’?iii aieeaa? ia ?ai?iaeoeoeaia caei?ia’y oea
iaie?aeiee oetha, caaaeueia /anoioa yeiai neeaaea? a?ae 10,0 aei
20,0 % (O.ss. Ioaie/ieeiaa, 1991; A.I.Aaioeeianueeee, 1994;
E.?.?aaithoa, 1995, 1996; C.A.Oe??ye-Ieaeiee, 1996; Michel F. et
al.,1993).

Iniaeeao o?eaiao aeeeeea? iaie?aei?noue o ae?iie, yea
cono??/a?oueny ii aeaieo ??cieo aaoi??a a?ae 47,5 % aei 70,0 % a
no?oeoo?? iaie?aeieo oetha?a (E.A.Aiae, 1990; E.A.Aiioei ?
I.A.Eiiiaaeia, 1992; R.I. Peperell et al.,1986).

??ciiiai?oi?noue iaoiaee/ieo i?aeoiae?a aei a?aeoai?aiiy
?ai?iaeoeoeaii? ooieoe?? oa ?o iaaeniea aoaeoeai?noue aeaco? ia
a?aenooi?noue ?nioaaiiy /?oeeo ciaiue ao?ieia?/ieo ? iaoiaaiaoe/ieo
iaoai?ci?a iioeiaeaeaiiy. Oey i?iaeaia noa? ua neeaaei?oith, eiee
i?e/eiith iaie?aeiino? ? 2, 3 a oi ? 4 /eiieee ? iinoa? ieoaiiy
aecia/aiiy iniiaiiai ?c ieo (A.I.Niaoiee e E.A.Ooieeiae/, 1990;
A.I.Aaneaeia, 1990; O.ss.Ioaie/ieeiaa, 1991; E.?.?aaithoa ? A.A.
Ei?iaoeueea, 1995).

Oea a ia?oo /a?ao noino?oueny iaoiaaiaco ii?ooaiiy ?ai?iaeoeoeaii?
ooieoe??, aiane?aeie ia?aianaiiai caiaeueiiai i?ioeano aai?oae?e (CIA) a
ii?aeiaii? c niaeeiaith oai?iaith i?aai?a iaeiai oaco oa /a?aaii?
ii?iaeieie, neiae?iiii iie?e?noicieo y?/iee?a (NIEss), aai?oaeueiei
aiaeiiao??icii (AA), o?a?ii?iiith iaoee (OI); ?ic?iaee iaoiae?a
ae?aaiinoeee, i?iaiicoaaiiy oa aeeoa?aioe?eiaaiiai i?aeoiaeo aei
??cieo iaoiae?a e?eoaaiiy oa i?io?eaeoeee.

Na?aae i?e/ei iaie?aeiino? a inoaii? ?iee cia/io oaaao noaee
i?eae?eyoe ?ioiieia?/iiio oaeoi?o (C.I.Aeoainna?neay, 1987;
A.I.*a?iuoia e E.E.Aaeaieia, 1988; I.A.Oaeo, 1989).

sseui oa?aeoa?enoeea i?noeaaeo niaoeeo?/ieo ? ianiaoeeo?/ieo
oaeoi??a caoenoo ? ?o oeeee?/ieo ci?i o caei?iaeo ae?iie
oa?oeeueiiai a?eo ? c ii?ooaiith ?ai?iaeoeoeaiith ooieoe??th i?e ie?aieo
aeaeao iaoieia?? aena?oeaia aeinoaoiuei aeaoaeueii (A.I.Naaaeueaaa e
E.A.Aioiiia, 1987; A.I.*a?iuoia, 1987,1988; E.E.Eaaithoa, 1992), oi
noai ?ioiiiai aiiainoaco a ne?iaaooe? e?ia? (NE), ia??oiiaaeuei?e (I?)
oa oie?eoey?i?e (O?) ??aeeiao aea/aiee cia/ii iaioa e iineoue
noia?a/eeaee oa?aeoa?.

Ia ?ice?eoith caeeoa?oueny ?ieue aaiiaeeiai?/ieo ? o?io?/ieo
?iceaae?a a aiaieu? iioeiaeaeaiiy ia aiaeie?eiii-?ioiiee aiiainoac
i?aai?cio ae?iee c ii?ooaiith ?ai?iaeoeoeaiith ooieoe??th.

Na?aae aaaaoueio ieoaiue i?iaeaie ii?aeiaieo oi?i
iaie?aeiino? iica oaaaith caeeoathoueny ieoaiiy iaoaaie?/ieo
iniaeeainoae a?ieia?/ieo oeaiei ? cie?aia, ?o aia?aaoe/iee iai?i, noai
i?i-oa aioeieneaeaioii? nenoai a e?ia? ? iniaeeai a oeaiei?
aiaeiiao??th.

I?e oeueiio iaeaea ia a?aoiao?oueny ii?oieia?/ia oa oeeoiaaiaoe/ia
ioe?iea iiaiioe?iiino? iioeeo?a, ?o nooi?iue c??eino? ? iiaeeea?noue
oe?eueiai? ?aaoeyoe?? aaiaoiaaiaco. I?io?eaeoeea, ae?aaiinoeea ?
e?eoaaiiy oeeo c?ooaiue, iniaeeai ia ?aii?o noaae?yo caoai?thaaiiy
i?aaenoaaey? cia/i? o?oaeiiu?.

Aiae?c e?oa?aoo?e iieacaa, ui ieoaiiy i?i aeei?enoaiiy oiai /e
?ioiai iaoiaeo e?eoaaiiy, ii/a?aiaino? eiai aeei?enoaiiy, iaaeo
eiina?aaoeaii? oa?ai?? ? iiaeeeaino? ia?aoiaeo aei o??o?a?/ii?
?aaa?e?oaoe?? aai aeei?enoaiiy iiaeo ?ai?iaeoeoeaieo oaoiieia?e
caeeoa?oueny ia cian?i ae??oaiei. Oiio aiae?c a?aeaeaeaieo ?acoeueoao?a
o??o?a?/iiai oa eiina?aaoeaiiai e?eoaaiiy ii?aeiaieo oi?i ae?ii/i?
iaie?aeiino? c oe?eeth i?iaiicoaaiiy eiai aoaeoeaiino? i?aaenoaaey?
aacnoii?aiee i?aeoe/iee ? oai?aoe/iee ?ioa?an.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie.

Ia?aiee iai?yiie aeine?aeaeaiiy o?nii iia’ycaiee c ieaiaie iaoeiai
aeine?aeieo ?ia?o ?IAA AII Oe?a?ie ( ? aea?ae?a?no?aoe?? 01.93.E
036275;

? 01.96.E 006280 ).

Iaoa ?iaioe. I?aeaeueoe aoaeoeai?noue ae?aaiinoeee oa e?eoaaiiy
iaie?aeiino? o oetha? ia iniia? iiaeeaeaiiai, eiiieaeniiai aea/aiiy
i?e/ei, iaoai?ci?a ?? ?icaeoeo ? noai?aiiy aeai?eoio i?iaiicoaaiiy
aoaeoeaiino? e?eoaaiiy, ui ni?eyoeia iaoeiaiio iaa?oiooaaiith ?
?ic?iaoe? aeeoa?aioe?eiaaieo iaoiae?a i?io?eaeoeee ? e?eoaaiiy
ii?aeiaieo oi?i iaie?aeiino? o oetha?.

Caaea/? aeine?aeaeaiiy.

1. Aea/eoe no?oeoo?o ? i?e/eie iaie?aeiino? a oetha? ia iniia?
ee?i?ei-noaoenoe/iiai aiae?co ?noi??e oai?iae ae?iie c iaie?aei?noth.

2. Aeaoe eiiieaenio ioe?ieo ooieoe?iiaeueiiai noaio
aioo??oi?o noaoaaeo i?aai?a ia iniia? aia?aoieo iaoiae?a
aeine?aeaeaiiy.

3. Aeynieoe ?ieue ?ioiieo, aiaeie?eiieo, a?io?i?/ieo oaeoi??a a
iaoiaaiac? ii?aeiaieo oi?i iaie?aeiino?.

4. Aea/eoe ooieoe?iiaeueiee noai ? aia?aaoe/iee iioaioe?ae
i?aaio-i?oai? — aiaeiiao??th o ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino?.

5. Aea/eoe oie?eoei- ? iiaaiac ? aeaoe oeeoiii?oieia?/io ?
oeeoiaaiaoe/io oa?aeoa?enoeeo iioeeo?a o ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino? a aeeiai?oe? iaino?oaeueiiai oeeeeo ? e?eoaaiiy.

6. ?ic?iaeoe aeeoa?aioe?eii-ae?aaiinoe/i? oaaeeoe?, e?eoa???
?aiiuei? ae?aaiinoeee ? aeai?eoie i?iaiicoaaiiy aoaeoeaiino? e?eoaaiiy
iaie?aeiino? a oetha?.

7. Iaoeiai iaa?oiooaaoe, ?ic?iaeoe ? ao?eeoe eiiieaen
i?aai?caoe?eieo, i?io?eaeoe/ieo ? e?eoaaeueieo caoiae?a, iai?aaeaieo
ia iiia?aaeaeaiiy ? oa?ai?th ii?aeiaieo oi?i iaie?aeiino? a
oetha?.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. O ?iaio? aia?oa:

— i?iaaaeaii eiiieaenia ee?i?ei-ia?aee?i?/ia ianoaaeaiiy ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? ? aecia/ai? iniiai? ? ae?oai?yaei?
/eiieee, ui iaaaoeaii aieeaathoue ia ?ai?iaeoeoeaio ooieoe?th ae?iee;

— oeyoii aeeiai?/iiai iine?aeiaiiai ianoaaeaiiy ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? c aeei?enoaiiyi no/anieo iaoiae?a
aeine?aeaeaiiy /ae?a?oaeueia noao?aeoe?eia
a?aeaiiao?inaeuei?iaia?ao?y (AeNAIN), aia?ia?ao?y (AeNA),
eaia?ineii?y (EN), a?noa?ineii?y (AN)/ anoaiiaeai? ia o?eueee
aiaoii?/i? ? ooieoe?iiaeuei? ci?ie a i?aaiao ? nenoaiao, aea e
aecia/aia eieae?caoe?y ? aeeaeia iioeiaeaeaiiy, ui aaaeeeai i?e
iiaeaeueo?e ?ic?iaoe? oaeoeee ei?aeoe?? aeyaeaieo ci?i;

— aeyaeai? iia? aeai? i?i aieea ??cieo iioeiaeaeoth/eo oaeoi??a ia
?icaeoie ? i?noea i?iaeoeoe?? aioenia?iaeueii? ?cinainea?e?caoe??,
aaoi?ioiieo ?aaeoe?e aei oeaieie y?/ieea o iaie?aeieo ae?iie,
yea iia’ycaia c iecueeei ??aiai NAe4 ia ii/aoeo ? a e?ioe?
iaino?oaeueiiai oeeeeo c iacia/iei i?aeaeuaiiyi eiai a ia??iaoeyoi?iee
ia??iae, i?eai?/aiiyi i?iaeoeoe?? i?iaanoa?iio, cieaeaiiyi ??ai?a
?ai?iaeoeoeaieo a?ee?a ??12 ? ??14;

— anoaiiaeaia ?icaaeainiaai?noue iieaciee?a ee?oeiiiai
caaaeueiiai ?ioi?oaoo a a?ieia?/ieo ??aeeiao a aeeiai?oe?
iaino?oaeueiiai oeeeeo, a?aenooi?noue noi?an?? a ia??iaoeyoi?iee
ia??iae o ae?iie c o?eaaeei i?io?eaiiyi caiaeueiiai i?ioeano ?
aiaeiiao??icii;

— anoaiiaeai? cia/i? ci?ie a?iio?ca?ii-aiiaaeii? nenoaie o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino?, ye? ia iaeiicia/i? ? caeaaeaoue a?ae
aeaeo iaoieia??, aeeaeie iioeiaeaeaiiy oiai /e ?ioiai i?aaio,
o?eaaeino? caoai?thaaiiy, ii?aeiaiiy aeae?eueeio /eiiee?a;

— ia iniia? aea/aiiy aia?aaoe/iiai iai?io a i?aai?-i?oai? o
ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? iieacaii a?ae’?iiee aieea
a?iiene/ieo ii?ooaiue a aiaeiiao???, anoaiiaeaia aeoeaaoe?y i?ioean?a
ia?aeeniiai ieeneaiiy e?i?ae?a ia oii? ?icaaeainiaaii? ?aaoeyoe?? oa
i?eai?/aiiy nenoaie aioeieneaeaioiiai caoenoo a ??cieo a?ieia?/ieo
na?aaeiaeuao ? aeieacaia ?ieue oeeo ii?ooaiue a aeieeiaii? iaie?aeiino?
ia ??ai? i?aeaoe?? caie?aeiaii? yeoeaee?oeie;

— aea/ai? iniaeeaino? oie?eoei- ? iiaaiaco o ae?iie c
iaie?aei?noth ii?aeiaiiai aaiaco ia iniia? eiiieaeniiai aeei?enoaiiy
oeueo?acaoeiaeo, oeeoiaaiaoe/ieo, oeeoiii?oieia?/ieo ?
oeueo?ano?oeoo?ieo iaoiae?a aeine?aeaeai-iy ? iieacaii iiceoeaiee aieea
aioo??oiueiaaiiiai eaca?iiai ii?ii?iaiiy e?ia? ia o?eueee ia
ai?iiiaeueiee aiiainoac ae?iee, aea ? cia/ii ciaioo? aeaaaia?aoeai?
ci?ie yaea?iiai iaoa??aeo iioeeoo.

— ?ic?iaeai? aeai?eoie i?iaiicoaaiiy aoaeoeaiino? e?eoaaiiy ae?iie
c ii?aeiaieie oi?iaie iaie?aeiino?, aeei?enoaiiy yeeo aeicaiey? nooo?ai
i?aeaeueoe i?ioeaio iiceoeaieo ?acoeueoao?a ? cai?iiiiiaai? iia?
e?eoa??? ae?aaiinoeee ii?aeiaieo oi?i iaie?aeiino?, ii/a?aia?noue
iaoiae?a ianoaaeaiiy a caeaaeiino? a?ae aeaeo iaoieia??, yeee aeeeeea?
ii?ooaiiy ?ai?iaeoeoeaii? ooieoe??;

— aaeineiiaeaia ? iaoeiai iaa?oioiaaia eiioeaioe?y iiaoaiiiai,
aeeoa?aioe?eiaaiiai, c o?aooaaiiyi ao?ieia?/ieo ? iaoiaaiaoe/ieo
/eiiee?a i?aeoiaeo aei nenoaie caoiae?a ii i?io?eaeoeoe? ? e?eoaaiith
ae?iie c iaie?aei?noth ii?aeiaiiai aaiaco, ui aeicaiey? cia/ii
i?aeaeueoe i?ioeaio iiceoeaieo ?acoeueoao?a.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. Iaa?oioiaaia
iaiao?aei?noue i?iaaaeaiiy iiaoaiiiai ee?i?ei-ia?aee?i?/iiai
ianoaaeaiiy iaie?aeii? ae?iee c iaoith aecia/aiiy iniiaii? ?
ae?oai?yaeii? i?e/eie iaie?aeiino?, aeeaeie iioeiaeaeaiiy i?aai?a ?
nenoai, ye? iaaaoeaii aieeaathoue ia ?ai?iaeoeoeaio ooieoe?th, a oaeiae
nai?/aniiai i?iaaaeaiiy nenoaie i?io?eaeoe/ieo ? e?eoaaeueieo
caoiae?a, ui cieaeothoue aai onoaathoue i?e/eie ye? i?ecaiaeyoue
aei iaie?aeiino?. ?ic?iaeaia ? cai?iiiiiaaia aeey canoinoaaiiy a
i?aeoe/i?e ioi?ii? caei?ia’y nenoaia aaoiiaoeciaaiiai
ee?i?ei-ia?aee?i?/iiai oanooaaiiy, ii/eiath/e c ae?ii/i? eiinoeueoaoe??
? cae?i/oth/e niaoe?ae?ciaaieie noaoe?iia?ieie a?aeae?eaiiyie.

?ic?iaeaia ? iaoeiai iaa?oioiaaia aeeoa?aioe?eiaaia oa?ai?y
??cieo oi?i ae?ii/i? iaie?aeiino? c o?aooaaiiyi ii?aeiaiiy o??? /e ?ioi?
iaoieia??, o?eaaeino? iaie?aeiino? ui i?ecaiaeeoue aei i?aeaeuaiiy
?acoeueoao?a e?eoaaiiy.

Cai?iiiiiaai? iia? iaoiaeeee ae?aaiinoeee iaie?aeiino? o ae?iie
ia ?aii?o aoaiao caoai?thaaiiy c aeei?enoaiiyi no/anieo
eiii’thoa?ii-aiaeiaaneoey?ieo iaoiae?a aeine?aeaeaiiy ? aea/aiiyi
ii?oiooieoe?iiaeueieo ci?i i?aaio-i?oai? (aiaeiiao??e), ui ni?ey?
aecia/aiith iniiaii? i?e/eie ii?ooaiiy ?ai?iaeoeoeaii? ooieoe?? ?
nai?/anii i?ecia/eoe aaeaeaaoio oa?ai?th.

?ic?iaeai? ? aaeineiiaeai? oa?i?ie ? e?eoa??? eiina?aaoeaii?
oa?ai?? ii?aeiaieo oi?i ae?ii/i? iaie?aeiino?, o??o?a?/iiai
e?eoaaiiy, a oaeiae iieacaiiy ? i?ioeiieacaiiy aei ooo/ii?
?inai?iaoe?? aeiii?nueeith aai nia?iith /ieia?ea, aeno?aei?ii?aeueiiai
caie?aeiaiiy.

Iniiai? i?eioeeie iiaoaiiiai ianoaaeaiiy ? aeeoa?aioe?eiaaiiai
e?eoaaiiy ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? ai?iaaaeaeai? a
i?aeoeeo ?iaioe ae?ii/eo eiinoeueoaoe?e.th aeooa?nueei-a?iaeieia?/ieo
noaoe?iia?ao, Aeiiaoeueei?, Caii??cueei? oa Oa?iii?euenueei? iaeanoae,
aeeth/ai? a oeeee eaeoe?e eo?n?a ?ioi?iaoe?? oa noaaeoaaiiy c
aeooaeueieo ieoaiue aeooa?noaa oa a?iaeieia?? i?e ?inoeooo? iaae?ao???,
aeooa?noaa oa a?iaeieia?? AII Oe?a?ie.

Ca iaoa??aeaie aeena?oaoe?? io?eiaii 3 iaoaioe ia aeiaoiaee: ?1412793 SU
“Niinia i?ioeeaeoeee niaa/iiai i?ioeanna a?thoiie iieinoe a
iineaiia?aoeeiiiue ia?eiae”, 1988; ?96125004 UA “Niin?a i?iaiicoaaiiy
aoaeoeaiino? e?eoaaiiy iaie?aeiino? o ae?iie”, 1997; ?95041759 UA
“Niin?a ae?aaiinoeee iaie?aeiino?”, 1998.

Ai?iaaoe?y ?iaioe. Iaoa??aee aeena?oaoe?? aeiiia?aeaeeny ia ?
c’?cae? aeooa??a-a?iaeieia?a Oo?eiai?noaio (Aooaaaae, 1988), ia
can?aeaii? i?nueeiai oiaa?enoaa aeooa??a-a?iaeieia?a (Ee?a, 1989),
neiiic?oi? ii i?iiaiaa?e ae?aaiinoeoe? (Ee?a, 1989), ia ?O ananithciiio
neiiic?oi? c i?aeia?iaeiith o/anoth «?ioiieia?y ?ai?iaeoeoe??» (Ee?a,
1990), ia iaoeiai-i?aeoe/i?e eiioa?aioe?? aeooa??a-a?iaeieia?a Oe?a?ie
(Aeiiaoeuee, 1994), ?O anana?oiueiio, ?? ?a?iiaenueeiio eiia?anao
aeooa??a-a?iaeieia?a (?niai?y, 1995), neiiic?oi? c i?aeia?iaeiith
o/anoth «Aeiiii?aei? ?ai?iaeoeoeai? oaoiieia??» (Ee?a, 1995)
neiiic?oi? c i?aeia?iaeiith o/anoth ii ?ioiieia?? (Ee?a, 1996), O
c’?cae? aeooa??a-a?iaeieia?a Oe?a?ie (Iaeana, 1996), ieaioi?
aeooa??a-a?iaeieia?a Oe?a?ie (*a?i?aoe?, 1997), iaoeiai-i?aeoe/i?e
eiioa?aioe?? «Aeooaeuei? ieoaiiy o??o?a??»
(Ee?a-Oiaeueieoeueeee-A?iieoey, 1997).

Iaoa??aee aeena?oaoe?? a?aeia?aaeai? a iaoiaee/ieo ?aeiiaiaeaoe?yo
“Iaoiaeu aeeaaiinoeee, ea/aiey e i?eioeeiu aeeniaina?ecaoeee aeaaooae e
aeaiuei, oa?iaeaaiuo ii ia?ooaieth ?ai?iaeoeoeaiie ooieoeee” (Eeaa, 1991
/ ni?aaao. E.?.?aaithoa, A.?.A?euaiei, ss.I.Nieuenueeee,
TH.I.A?oiei-Aieueoiaa, ?.A.Aiae, A.N.Aeoa/ae, A.O.Iaoa?ao?anueea,
I.O.Eaueinueeee, TH.?.Ia?auoe, C.I.Aeoainna?neay, A.A *oa, I.N.
Niaae?e), “Iaiaaeeeaiaioici? iaoiaee e?eoaaiiy caaaeueieo caoai?thaaiue
aai?oae?e (Ee?a, 1993 /ni?aaao. A.?. A?euaiei, E.?.?aaithoa,
A.?.Aeoa/ae, C.I.Aeoaina?nueea).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 29 i?aoeue, ?c
ieo 10 noaooae, 3 iaoaioe, 2 — a iaoeiaeo ca??ieeao, 14 — a oacao ?
iaoa??aeao aeiiia?aeae iaoeiaeo eiioa?aioe?e.

Ianya oa no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 308
noi??ieao iaoeiiieniiai oaenoo, ?ethno?iaaia 22 iaethieaie ? 56
oaaeeoeyie, ye? caeiathoue 40 noi??iie. Neeaaea?oueny ?c anooio,
iaeyaeo e?oa?aoo?e, 7 ?icae?e?a aeanieo aeine?aeaeaiue,
caeeth/aiiy, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo e?oa?aoo?e,
yeee aeeth/a? 450 aeaea?ae a?o/eciyieo oa ca?oa?aeieo aaoi??a, ui
caeiathoue 47 noi??iie.

Iniaenoee aianie caeiaoaa/a. I?iaaaeaii aeaoaeueiee
ee?i?ei-ia?aee?i?/iee aiae?c ianoaaeaiue 500 oai?eo c ii?aeiaieie
oi?iaie iaie?aeiino?. Aaoi? ?ic?iaea aeai?eoi i?iaiicoaaiiy
aoaeoeaiino? e?eoaaiiy iaie?aeiino?, aecia/ea e?eoa??? ae?aaiinoeee ia
?aii?o aoaiao caoai?thaaiiy ? i?ney e?eoaaiiy. Cai?iiiioaaa ?
ai?iaaaeea iia? iaoiaeeee ae?aaiinoeee ooieoe?iiaeueiiai noaio
iaoeiaeo o?oa oa aaiiaeeiai?ee i?aai?a iaeiai oaco c aeei?enoaiiyi
iiaeo eiii’thoa?ii-aiaeiaaneoey?ieo iaoiae?a aeine?aeaeaiiy. Anoaiiaea
iia? e?eoa??? ae?aaiinoeee iaie?aeiino? ii?aeiaiiai aaiaco,
aeeth/ath/e i?aaie-i?oai? (y?/ieee, aiaeiiao??e). ?ic?iaea iia? noaie
?iaeoeoe?? iaoeyoe??, aeeth/ath/e iaai?iiiaeuei? iaoiaee. Aea/ea
oeeoiii?oieia?/i? ? oeeoiaaiaoe/i? iniaeeaino? iioeeoo o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino?. ?ic?iaea ? iaa?oiooaaa iaoiaee
i?io?eaeoeee ? e?eoaaiiy iaie?aeiino? o ae?iie. I?ia?a aeeiai?/ia
niinoa?aaeaiiy ae?iie a i?ioean? eiina?aaoeaii? oa o??o?a?/ii?
?aaa?e?oaoe?e. Aeeiiaa iniiaio /anoeio aia?ia?ao?/ieo,
a?aeaiiao?i-naeuei?iaia?ao?/ieo, aiaeineii?/ieo iaoiae?a
aeine?aeaeaiiy. Aea/aa ca aeiiiiiaith noao?aeoe?eii?
ae?a?oaeueii? aia?ia?ao?? aaiiaeeiai?eo i?aai?a iaeiai oaco o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? ? aecia/ea oa?aeoa?i? aia?ia?ao?/i?
iciaee aeey ??cii? iaoieia??, aeeth/ath/e o?ii?/iee caiaeueiee
i?ioean aai?oae?e, neiae?ii iie?e?noicieo y?/iee?a, o?a?ii?iio iaoee
oa aai?oaeueiee aiaeiiao??ic. ?ioa?i?aooaaa iaea?aeai? ?acoeueoaoe,
c?iaea aeniiaee ? ?ic?iaea i?aeoe/i? ?aeiiaiaeaoe??.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy. Aeey ae??oaiiy iinoaaeaieo
caaaeaiue iaie anaa?/ii ianoaaeaii 500 ae?iie c iaie?aei?noth
ii?aeiaiiai aaiaco, a oiio /ene? 190 ae?iie, o yeeo iaie?aei?noue
aoea iaoiiaeaia o?ii?/iei naeuei?ia?oii a ii?aeiaii? c
ia??naeuei?ia?oii (? ee?i?/ia a?oia), 142 ae?iee, o yeeo iaie?aei?noue
aeieeea aiane?aeie o?eaaeiai o?ii?/iiai naeuei?ia?oo ? aoi?eiii
iaoiiaeaiiai NIEss (?? ee?i?/ia a?oia), 77 ae?iie c NIEss a ii?aeiaii?
c o?ii?/iei naeuei?ia?oii (??? ee?i?/ia a?oia), 45 ae?iie o yeeo
iaie?aei?noue caiaeueiiai aaiaco aoea ii?aeiaia c AA (IV ee?i?/ia a?oia)
? 46 iaie?aeieo ae?iie aea o?ii?/iee naeuei?ia?o ii?aeioaaany c OI (V
ee?i?/ia a?oia). A?oio eiio?ieth ii aeiaeaoeiaeo iaoiaeao
aeine?aeaeaiue neeaee 132 ae?iee c iaii?ooaiith ?ai?iaeoeoeaiith
ooieoe??th.

Ianoaaeaiiy i?iaiaeeeenue a a?aeae?eaii? ?aaa?e?oaoe??
?ai?iaeoeoeaii? ooieoe?? ae?iie ?inoeoooo iaae?ao???, aeooa?noaa oa
a?iaeieia?? AII Oe?a?ie (ea??aiee — i?io. E.?.?aaithoa).

?acoeueoaoe ianoaaeaiiy ? e?eoaaiiy ae?iie iaeiie/oaaeenue ca
aeiiiiiaith niaoe?aeueii ?ic?iaeaii? oi?iae?ciaaii? ?noi??? oai?iae.

O an?o ae?iie ii?yae ?c caaaeueiii?eeiyoeie ee?i?ei-eaai?aoi?ieie
? ?ino?oiaioaeueieie aeine?aeaeaiiyie i?iaiaeeeenue niaoe?aeuei?
iaoiaee aeine?aeaeaiiy ?ai?iaeoeoeaii? ooieoe?? ae?iee (?ioiieia?/i?,
aiaeie?eiieia?/i?, a?io?i?/i?, ii?oieia?/i?, ?aioaaiieia?/i?,
aia?ia?ao?/i?, aiaeineii?/i?, aoia?ao?/i?, oa?iia?ao?/i?).

Ooieoe?iiaeueiee noai y?/iee?a ioe?ithaaany ca ?acoeueoaoaie oano?a
ooieoe?iiaeueii? ae?aaiinoeee.

Oa?oeeuei?noue /ieia?ea aecia/aeanue ca ?acoeueoaoaie nia?iia?ai c
o?aooaaiiyi ?aeiiaiaeaoe?e AIIC.

Aeey aecia/aiiy aiaoii?/ieo ? ooieoe?iiaeueieo ci?i iaoee, iaoeiaeo
o?oa, e??i caaaeueiii?eeiyoeo ?aioaaiieia?/ieo aeine?aeaeaiue
(iao?inaeuei?iai-a?ao?y, iaeuea?ia?ao?y, a?eiino?anoia a?iaeia?ao?y)
iaie aeei?enoiaoaaeanue ae?a?oaeueia noao?aeoe?eia
a?aeainaeuei?iaia?ao?y (AeNAINA) ia aia?ia?ao? o??ie «Simens»
(I?ia//eia).

Aeey aea/aiiy aaiiaeeiaieee i?aai?a iaeiai oaco aeei?enoiaoaaee
AeNA. E??i oiai, iaoiae AeNA ii?aeioaaany c AeNAINA.

Ii?yae c oeei ie canoiniaoaaee aiaeineii?/i? iaoiaee
aeine?aeaeaiiy (EN ? AN) ca aeiiiiiaith eaia?ineiia ? a?noa?ineiia o??ie
«Karl Storz» (I?ia//eia).

Aeey ioe?iee ooieoe?iiaeueiiai noaio y?/iee?a aeei?enoiaoaaee
oeueo?acaoeiaee iii?oi?eia ca aeiiiiiaith aia?aoo «Aloka-SSD-256»
(ssiii?y) c naeoi?aeueiei aeao/eeii c /anoioith 3,5 iAoe.

A aeeiai?oe? iaino?oaeueiiai oeeeeo ? a i?ioean? e?eoaaiiy
i?iaiaeeee aecia/aiiy ano?aae?ieo, i?iaanoa?iio, oanoinoa?iio,
ethoai?coth/iai (EA) oa oie?eoeinoeioethth/iai ai?iii?a (ONA),
i?ieaeoeio a ne?iaaooe? e?ia? ?aae?i?ioiieia?/iei iaoiaeii.

?ioiieia?/i? aeine?aeaeaiiy i?iaiaeeee a aeeiai?oe?
iaino?oaeueiiai oeeeeo a NE, I?, O?, OeN ianoaaeaieo ae?iie. Aecia/aee
??ai? ?ioiiaeiaoe?i?a iaoiaeii ?aae?aeueii? ?ioiiaeeooc?? ii Mancini
et al. (1965), e?cioeeio — iaoiaeii ?aae?aeueii? ?ioiiaeeooc?? a aae?
i?e?iiaoiaeii ii I.N. Iioaaeei?e ? ni?aaao.(1979). Noaiiioeyoe?eiee
neeaae e?ioioeeo?a aea/aee ca aeiiiiiaith iaoiaeo i?ioi/ii?
oeeoioeoi?eiao??? ia oeeoioeoi?eiao?? «Fascan» o??ie «Becton Discinson»
c canoinoaaiiyi iiiieeiiaeueieo aioeo?e.

Aeey aea/aiiy aaoinainea?e?caoe?? aea/aee aioeo?ea aei
iaa??aeueieo aioeaai?a ca iaoiaeeeith A.Sacco,(1987) ? aei
a?aioeueicieo ee?oei c canoinoaaiiyi e??inoaoieo c??c?a y?/ieea.

Ooieoe?iiaeueio aeoeai?noue O-e?ioioeeo?a ioe?ithaaee ii
caaaeueii-i?eeiyoiio iaoiaeo c aeei?enoaiiyi o?oiaaiaaetho?i?ia o??ie
«Difco». ??ai? ?ai?iaeoeoeaieo a?ee?a — ieaoeaioa?iiai i?e?iaeiaoe?io
(??13) oa i?e?iaeiaoe?io oa?oeeueiino? (??14 ) aecia/aee
?ioiioa?iaioiei iaoiaeii c aeei?enoaiiyi iaai??a III «Aeeaaiinoeeoi»
(Iineaa).

I?eaeeoo?aa oeeoiii?oieia?/ia aeine?aeaeaiiy iioeeo?a
i?iaiaeeeinue ca iaoiaeeeith Tarkowski A. (1966) i?ae eiio?ieai
noa?aii?e?ineiia c aeei?enoaiiyi aeaeo?iiiiai i?e?ineiia «I-600».

Aeoeai?noue oa?iaio?a aeeoaeueiiai eaioethaa a aiaeiiao???
aea/aeenue ia 19-23 aei? iaino?oaeueiiai oeeeeo oeyoii aecia/aiiy
aeoeaiino? IAAeI-aeaa?ae?iaaiace (Shats et al.,1963),
noeoeeiao-aeaa?ae?iaaiace (King, 1963), oeeoio?ii-c-ieneaeace (Watrom
D.S. et al.,1967), IAAeI-noeoeeiao-oeeoio?ii-N-?aaeoeoace (Bernstein
I.D. et al., 1978).

A NE, iaia?aiao a?eo?ioeeo?a ? aaiiaaiaoao aiaeiiao??th
ianoaaeaieo ae?iie aea/aee iniaeeaino? niaeo?o iaeo?aeueieo e?i?ae?a
oa oinoie?i?ae?a ca?aeii ?aeiiaiaeaoe?e Eaeona (1973).

On? iaea?aeai? aeai? ee?i?ei-ia?aee?i?/ieo aeine?aeaeaiue
ia?iaeaii iaoiaeii aa??aoe?eii? noaoenoeee, ei?aeyoe?eiiai
aiae?co. Aeai?eoi i?iaiicoaaiiy aoaeoeaiino? e?eoaaiiy ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? noai?aiee ia iniia? ia?aiao?e/ii?
i?ioeaaeo?e ?ici?ciaaaiiy, ?ic?iaeaii? A.A.Aoaea?ii (1990).

Iaoaiaoe/ia ia?iaea iaea?aeaieo ?acoeueoao?a aeeiioaaeanue ca
aeiiiiiaith niaoe?aeueii ?ic?iaeaiiai i?ia?aiiiai caaacia/aiiy, ui
?aae?co? aeuaaeacai? iaoiaee ? aeai?eoi i?iaiicoaaiiy ia IAII ?AI
?N/AO.

?acoeueoaoe aeanieo aeine?aeaeaiue oa ?o iaaiai?aiiy. Aiae?c
io?eiaieo aeaieo iieacaa, ui an? ianoaaeai? ae?iee aoee a
?ai?iaeoeoeaiiio a?oe? a?ae 17 aei 40 ?ie?a.

Ee?i?/ia ea?oeia ae?ii/i? iaie?aeiino? ii?aeiaiiai aaiaco
iaoiiaeaia oeie iaoieia?/ieie ci?iaie a i?aaiao ? nenoaiao, ye?
aeeeeeathoue oeth iaoieia?th. sseui aeey oai?eo ?, ?? ee?i?/ii?
a?oie oa?aeoa?i? iciaee o?eaaeiai caiaeueiiai i?ioeano — ae?aaeai?
aiaoii?/i? ci?ie i?aai?a iaeiai oaco, aoi?eiia aeenooieoe?y
aiaeie?eiii? nenoaie, oi aeey oai?eo c NIEss a ii?aeiaii? c caiaeueiei
i?ioeanii (??? ee?i?/ia a?oia) oa?aeoa?i? i?ci? iaia?oa, ii?ooaiiy
iaino?oaeueii? ooieoe?? ii oeio ie?ai-, aiaii?a?, ia?aaaaa ia?aeiii?
iaie?aeiino? iaae aoi?eiiith (iaeaea a 3 ?ace), ae?aaeaiee a??nooiee
neiae?ii, a?iiieac?y iaoee.

Aeey iaoe??ioie c aaeaiii?icii oa o?a?ii?iiith iaoee (?V oa V
ee?i?/ieo a?oi) oa?aeoa?i? — ia?aaaaeii aoi?eiia
iaie?aei?noue, iayai?noue a aiaiiac? ooo/ieo aai?o?a, ii?ooaiiy
iaino?oaoe?? ii oeio a?ia?iie?iaii?a?, iaii?aa??, aeueaiaeeniaii?a?,
ca?eueoaiiy ?ici???a iaoee, ?? iaiaeii??aei?noue.

I?i ooieoe?iiaeueiee noai iaoeiaeo o?oa oa aaiiaeeiai?eo i?aai?a
iaeiai oaco o ianoaaeaieo ae?iie ie noaeeee ca aeaieie AeNAINA ? NAeA.

I?iaaaeaiee aiae?c a?aeaia?ai, a naia eiio?anooaaiiy ii?iaeieie
iaoee, aeicaieea aeae?eeoe aeae?eueea aa??aio?a ?aioaaiieia?/ii?
ea?oeie, oa?aeoa?ieo aeey oai?eo IV i V ee?i?/ieo a?oi, oae ye aeey
oai?eo ?, ??, ??? ee?i?/ieo a?oi, noai iaoee i?/ei ia a?ae??ciyany a?ae
?acoeueoao?a INA.

Oe?iiei ae?aaiinoe/iei iaoiaeii aeyaeeinue AeNAINA i?e
ae?aaiinoeoe? i?io?aeiino? iaoeiaeo o?oa o ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino?. I?io?aeieie o?oae aoee o 19,4 % ae?iie — ?, 11,9 % —
??, 90,0 % — ???, 10,0 % — IV i 55,6 % — V a?oi, aea a a?eueoino?
oai?eo, e??i oai?eo c NIEss ? o?ii?/iei naeuei?ia?oii (O a?oia) o?oae
aoee /anoeiai i?io?aeieie aai iai?io?aeieie.

sseui aeey oai?eo ? ? ?? ee?i?/ii? a?oie (23,0 %; 23,8 %,
a?aeiia?aeii), o?oae oa?aeoa?ecoaaeenue ianeio?iiiei /ioeiiiae?aiei
caiiaiaiiyi iaio o?oa, ooai?aiiyi naeoinaeuei?ien?a (19,4 %; 33,3 %,
a?aeiia?aeii), oi aeey oai?eo c aai?oaeueiei aiaeiiao??icii a
ii?aeiaii? c OCIANI ( IV a?oia) iai?io?aei?noue niinoa??aaeanue a
?io?aio?aeueiiio ? ?noi?/iiio a?aeae?e?(10,0 % ? 13,3 %,
a?aeiia?aeii) c iiiaeeiieie o?nooeaie a ?noi?/i?e /anoei? o?oae ( 56,6
%).

Aeey aea/aiiy aaiiaeeiai?ee i?aai?a iaeiai oaco o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? aoei canoiniaaii AeNA, yea
aeeth/aea a naaa caaaeueio, naeaeoeaio ? noia?naeaeoeaio
aia?ia?ao?th. sse?nio oa?aeoa?enoeeo aia?ia?ai i?iaiaeeee a
a?oa??aeuei?e, ia?aio?iaoici?e ? aaiici?e oacao aeine?aeaeaiiy.

A caeaaeiino? a?ae oa?aeoa?o noaeeiieo ci?i aia?ia?aie oai?eo
c o?ii?/iei naeuei?ia?oii, ia??naeuei?ia?oii ? aoi?eiiei NIEss aoee
?icae?eai? ia aeaa oeie.

Aeey ? oeio oa?aeoa?iee ii?iiaaneoey?iee oei e?iaiiinoa/aiiy, yeee
oa?aeoa?ecoaaany /?oeeie eiioo?aie ye noaeei ? ? ?? ii?yaeeo, oae ?
noaeei ??? ? IV ii?yaeeo. A ia?aio?iaoicio oaco aeine?aeaeaiiy
niinoa??aaeanue ?icaaeoaeaia n?oea eai?ey?ieo noaeei o aeaeyae? «oooiai?
yaiaee», yea iaiaaeo?oueny iaoeith ? y?/ieeaie.

?? oei aia?ia?ai iaa oa?aeoa?i? aia?ia?ao?/i? iciaee: ?icoe?aiiy
noaeei ?? ? ??? ii?yaeeo c caoaeaiiyi noaeei IV ii?yaeeo,
ianeiao?e/i?noue noaeeiieo ci?i, ca?aei?iiyi eai?ey?ieo noaeei IV
ii?yaeeo a ia?aio?iaoicio oaco.

I?e i?iaaaeaii? ee?i?ei-aia?ia?ao?/ieo ia?aeaeae anoaiiaeaii, ui
aeey ae?iie c ? oeiii aia?ia?ai oa?aeoa?ia o?eaae?noue iaie?aeiino?
a?ae 1 aei 4 ?ie?a, ooieoe?iiaeuei? ci?ie a i?aaiao ? nenoaiao, a oie
/an ye o ae?iie c ?? oeiii aia?ia?ai o?eaae?noue iaie?aeiino? aoea a?ae
7 aei 11 ?ie?a, niinoa??aaeenue a?oa? aiaoii?/i? ci?ie aioo??oi?o
noaoaaeo i?aai?a, ye? i?aeoaa?aeeeeny i?ae /an eaia?ineii?? ?
o??o?a?/iiai ao?o/aiiy.

Aia?ia?aie o oai?eo c NIEss (O a?oia) iaee ii?iiaaneoey?iee oei
e?iaiiinoa/aiiy.

Aia?ia?ao?/i? aeine?aeaeaiiy o oai?eo c aai?oaeueiei
aiaeiiao??icii /e o?a?ii?iiith iaoee (IV i V a?oie) aeicaieeee aeyaeoe
aiaeiiao??i?aei? ?io?eueo?aoe, iaaeo ?icaaeoaeaiino?, a?coae?coaaoe
e?iaiiinoa/ath/? a?oa??aeuei? noaeeie, aaie, ii yeeo a?aeaoaa?oueny
a?aeoie e?ia?. Oea aeicaieeei anoaiiaeoe oiiia?aoiaiaoii?/i?
ni?aa?aeiioaiiy aoce?a aai aiaeiiao??i?aeiiai ?io?eueo?aoo c noaeeiaie
iaeiai oaco. E??i oiai, a i?ioean? aeine?aeaeaiiy ie ciiaee
i?iaiae?coaaoe o?ae na/iaiae?a, ye? a?coae?coaaeenue ia 5 oaeeei?
aeine?aeaeaiiy.

I?e aoceoaaoeo OI aeyaeaii iaeiia?/ia aai aeaia?/ia ?icoe?aiiy
a?oa??aeueieo noaeei ?? ? ??? ii?yaee?a c ?icaaeoaeai?noth noaeei IV
i V ii?yaee?a ? iiyaith iiaeo noaeei ? ooai?aiiyi eai?ey?ii-aaiicieo
eaaoi, ?icoe?aiiyi aai.

Iaea?aeai? aeai? i?i aaiiaeeiai?eo i?aai?a iaeiai oaco o ae?iie
c iaie?aei?noth caiaeueiiai aaiaco aeicaieeee i?eionoeoe, ui
a?iiene/i? yaeua a i?aaiao i?oaiyo i?ecaiaeyoue aei ii?ooaiiy
aaaaoueio ooieoe?e noaoaaiai aia?aoo o ae?iie, a oiio /ene?
?ai?iaeoeoe??.

Aiaoiii-ooieoe?iiaeueiee noai aioo??oi?o i?aai?a ianoaaeaieo ae?iie
ioe?ithaaee ca aeaieie EA ? AN.

Eaia?ineii?th i?iaaaeaii o 145 ae?iie — aea iaeiith ?c i?e/ei
iaie?aeiino? aoei OCA, c ieo o 19 (13,1 %) aoa niaeeiaee i?ioean iaeiai
oaco (? ee?i?/ia a?oia); o 57 (39,3 %) — aoi?eiiee NIEss (?? a?oia);
o 18 (12,4 %) — ia?aeiii neiae?ii iie?e?noicieo y?/iee?a (???
a?oia); o 41 ( 29,1 %) aai?oaeueiee aiaeiiao??ic (IV a?oia);
o 10 (6,1 %) o?a?ii?iia iaoee (V a?oia).

Aeey aecia/aiiy aioo??oiueiiaoeiai? iaoieia?? o 200 oai?eo c
ii?aeiaieie oi?iaie iaie?aeiino? i?iaaaeaia ??aeeiia AN.

?acoeueoaoe AN iieacaee, ui a 26,0 % aeiaaee?a aeyaeaia
a?ia?ieac?y aiaeiiao??th; o 15,0 % — iie?ie aiaeiiao??th; 7,0 % —
i?aeneecia? o?a?iiaoici? aocee; 6,0 % — aiaeiiao??i?aei? oiaee; 3,0 % —
aioo??oiueiiaoeia? neiao??; 15,0 % — a?iio?io?y ? ao?io?y aiaeiiao??th;
o 1,0 % — aiiiae?y ?icaeoeo iaoee; o 3,0 % — aeaoi?iaoe?? iaoee ca
?aooiie ?ioa?io?aeueieo o?a?iiaoicieo aoce?a; o 13,0 % — a?ia?ieac?y
aiaeiiao??th c iie?iicieie ?ic?inoaiiyie.

I?e a?noieia?/iiio aeine?aeaeaii? iaea?aeaiiai iaoa??aeo o 24, 0
% ae?iie aeyaeaia caeicenoa a?ia?ieac?y aiaeiiao??th c nae?aoi?iith
o?anoi?iaoe??th caeic; o 13,0 % — caeiceno? iie?ie; o 7,0 % —
aeenieanoe/iee aiaeiiao??e ano?iaaiiiai oeio; o 14,0 % — a?iiieac?y oa
ao?io?/i? ci?ie aiaeiiao??th. O 3,0 % ii?yae c ao?io??th aiaeiiao??th
iaa i?noea neea?ic no?iie ? o 2,0 % ianoaaeaieo ae?iie aoea aeyaeaia
aoeiiaa oi?ia caeicenoi-eenoicii? a?ia?ieac?? aiaeiiao??th. O 27,0
% ae?iie a?aei?/aeenue iciaee o?ii?/iiai ?aoeeaeeaoth/iai
aiaeiiao??ico. Eeoa o 5,0 % ae?iie ca aeaieie iaoia?noieia?/iiai
aeine?aeaeaiiy aiaeiiao??e a aeoe??aeao aoa i?ciuei? oace nae?aoe??.

Oaeei /eiii, i?iaaaeai? ?ino?oiaioaeuei? aeine?aeaeaiiy o oai?eo
c ii?aeiaieie oi?iaie iaie?aeiino? aeicaieeee aecia/eoe ii/a?aia?noue ?
?ioi?iaoeai?noue iaoiae?a aeine?aeaeaiiy a caeaaeiino? a?ae ii?aeiaiiy
o??? /e ?ioi? iaoieia??, yea i?ecaaea aei iaie?aeiino?. Oae, aeey ae?iie
c o?ii?/iei naeuei?ia?oii ? ia??naeuei?ia?oii ? aoi?eiiei
neiae?iiii iie?e?noicieo y?/iee?a ianoaaeaiiy ne?ae ii/eiaoe c
oano?a ooieoe?iiaeueii? ae?aaiinoeee, oeueo?acaoeiaiai aeine?aeaeaiiy
i?aai?a iaeiai oaco oa iao?inaeuei?iaia?ao??, AeNAINA, oi aeey ae?iie
c neiae?iiii iie?e?noicieo y?/iee?a a ii?aeiaii? c o?ii?/iei
naeuei?ia?oii iaia’yceiaei ? i?iaaaeaiiy a?eiio?anoii?
a?iaeia?ao??, iaeuea?ia?ao??, aaaeaii EN. Ia?aaaaith
eaia?ineii?/iiai aeine?aeaeaiiy ? eiai ii?aeiaiiy c i?iaaaeaiiyi
o??o?a?/ii? ei?aeoe?? (ae?aoa?iiioieoo?a aai ae?aoa?iieaooa?ecaoe?y
y?/iee?a, naeuei?iaiiaa??ie?c?n).

O ae?iie c aai?oaeueiei aiaeiiao??icii ? o?a?ii?iiith iaoee (IV i
V ee?i?/i? a?oie) ianoaaeaiiy iaiao?aeii aeiiiaieoe ca ?aooiie
a?noi?ineii??, a?noieia?/iei aeine?aeaeaiiyi aiaeiiao??th,
aia?ia?ao??.

Aea/aiiy ee?oeiiiai oa aoii?aeueiiai ?ioi?oaoo o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? iieacaei cieaeaiiy caaaeueii? oa
i?noeaai? ianiaoeeo?/ii? ?acenoaioiino?, a oaeiae ii?ooaiiy a O- e
A-nenoai? ?ioi?oaoo.

Aiae?c noaio ?ioiiiai noaoono ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino? na?ae/aoue i?i iayai?noue o ieo iaaieo ci?i ?ioiieia?/ieo
iieaciee?a. A ia?oo /a?ao cieaeaiiy i?ioeaioiiai ai?noo O- oa
A-e?ioioeeo?a a ne?iaaooe? e?ia? iaea?eueo ae?aaeaia a a?oi? ae?iie c
aiaeiiao??icii ( 40,4+0,6 % ? 14,9+0,4 %, a?aeiia?aeii, i?ioe 53,7+0,7
% ? 23,3+0,7 % a eiio?ie?).

A ca’yceo c a?aenooi?noth nooo?aeo ci?i ee?oeiiiai oa
aoii?aeueiiai ?ioi?oaoo a a?ieia?/ieo ??aeeiao a caeaaeiino? a?ae
ee?i?/ieo a?oi, iiaeaeueo? aeai? aeeeaaeai? a caeaaeiino? a?ae ci?i
aioenia?iaeueii? ?cinainea?e?caoe??.

I?e aea/aii? aioenia?iaeueii? nainea?e?caoe?? anoaiiaeaii, ui
nia?i?iia?e?coth/? aioeo?ea (N?AO) a NE aeyaeai? o 14,4 % ae?iie, a
OeN — o 44,7 % ae?iie, a O? — o 22,4 % ? a I? — o 25,0 % N?AO
iaeii/anii a on?o noano?aoao aoee aeyaeai? o?eueee o 2,6 % oai?eo, a
OeN ? I? — o 15,8 % ae?iie, a OeN ? O? — o 4,0 % ae?iie, a O? ? I? — o
4,0 %.

Ni?anoaaeaiiy noaio i?noeaaeo oaeoi??a caoenoo c i?iaeoeoe??th
N?AO, na?ae/aoue, ui i?iaeoeoe?y N?AO a oea?a?eaeueiiio neeco
iia’ycaia c iaaeinoaoi?noth i?noeaaiai ?ioi?oaoo, a naia, c iecueeei
??aiai nae?aoi?iiai IgA.

Iao? aeai? oaeiae na?ae/aoue i?i ?nioaaiiy oe???
caeiiii??iino? ? aeey iieaciee?a ?ioi?oaoo a I? ? O?, ine?eueee
iayai?noue N?AO a I? ? O? iia’ycaia oaeiae c ae?aaeaiei cieaeaiiyi
??ai?a SIgA, IgA ? e?cioeeio.

Oaeei /eiii, iaaeinoaoi?noue i?noeaaiai ?ioi?oaoo yaey?oueny
ni?eyoeeaei oiiii aeey ?icaeoeo i?noeaai? aioenia?iaeueii?
?cinainea?e?caoe??.

I?e aea/aii? i?noeaaiai ? aoii?aeueiiai ?ioi?oaoo a caeaaeiino?
a?ae oace iaino?oaeueiiai oeeeeo anoaiiaeaii, ui o ae?iie c
ii?aeiaieie oi?iaie iaie?aeiino? a?aenooi? /?oei ae?aaeai? ci?ie
??ai?a O- ? A-e?ioioeeo?a a caeaaeiino? a?ae oace iaino?oaeueiiai
oeeeeo. Oea a?aeiineoueny ye aei ?o iieaciee?a a NE, oae ? aei
iieaciee?a O? ? I?.

I?iaaaeai? aeine?aeaeaiiy ?ioiiaeiaoe?i?a ? e?cioeeio a ne?iaaooe?
e?ia? ? oea?a?eaeueiiio neeco na?ae/aoue i?i a?aenooi?noue noi?anoaaiiy
?ioiii? a?aeiia?ae?, ye? iaiao?aei? a ia??iaoeyoi?iee ia??iae aeey
ii?iaeueiiai o?ainii?oo nia?i??a. I?aeaeuaiiy IgI a OeN ? I? iiaea
ni?eyoe aeoeaaoe?? aoaeoi?ieo ?ioiieo iaoai?ci?a, iai?aaeaieo ia
ae?i?iaoe?th nia?iaeueieo aioeaai?a.

I?e aea/aii? aaoi?ioiii? aa?an?? o ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino? anoaiiaeaii, ui o 31,5 % ae?iie aeyaeai? aaoiaioeo?ea aei
Zona pellucida (ZP) yeoeaee?oeie, o — 10,5 % aaoiaioeo?ea aei
a?aioeueicieo ee?oei, a oiio /ene? o 5,2 % aioeo?ea aeyaeai? iaeii/anii
aei ZP ? a?aioeueicieo ee?oei.

Aeeiai?/ia aea/aiiy ??ai?a ?aaoeyoi?ieo noaiiioeyoe?e
O-e?ioioeeo?a ia i?ioyc? iaino?oaeueiiai oeeeeo aeyaeei cia/i? c?ooaiiy
a iai?yieo ci?i o ae?iie c aaoi?ioiieie ?aaeoe?yie (Oaae. 1).

Oae, a a?oi? ae?iie c aaoiaioeo?eaie iaeieae/? ??ai? NAe4+
aeyaeyeenue ia ii/aoeo oa a e?ioe? oeeeeo. A na?aaeei? oeeeeo, oiaoi
a ia??iaoeyoi?iiio ia??iae?, iaei eeoa cia/ia i?aeaeuaiiy a?aeiiniiai
ai?noo oe??? noaiiioeyoe?? O-e?ioioeeo?a, i?e/iio iaea?eueo ae?aaeaia
oea i?aeaeuaiiy ia I-aeaiue. I?ney iaoeyoe?? ??aaiue NAe4+
(O-oaeia??a) cieaeoaaany.

O iaie?aeieo ae?iie aac aaoi?ioiieo ?aaeoe?e oa o caei?iaeo
a?aeiiniee ai?no NAe4+ (O-oaeia??a) ia? cai?ioio iai?aaeai?noue a
aeeiai?oe? oeeeeo. Iaea?eueo aenie? eiai cia/aiiy oa?aeoa?i? aeey
ii/aoeo oa e?ioey oeeeeo, a a ia??iaoeyoi?iiio ia??iae? oeae iieaciee
cia/ii cieaeo?oueny, c aenieei nooiaiai a??ia?aeiino?. sse ? a
aeiaaeeo c NAe4+ -e?ioioeeoaie, iaea?eueo aecia/ai? oe? ci?ie ia
0-aeaiue.

Oaaeeoey 1 — A?aeiiniee ai?no ?aaoeyoi?ieo noaiieyoe?e O-e?ioioeeo?a oa
?o ni?aa?aeiioaiiy a aeeiai?oe? iaino?oaeueiiai oeeeeo o iaie?aeieo oa
caei?iaeo ae?iie, (a?aei. %)

?ioiieia?/-i? iieacieeeA?oia oai-?eonAeaiue iaino?oaeueiiai oeeeeo

8(1)-1(2)?1-20(3)?1-3+1(4)?1-421(5)?3-526(5)?3-5)O-oaeia-a2433.0+2.941.8
+2.5<0.0547.1+2.4<0.0537.8+4.5>0.0532.7+3.8<0.0533.3+5.7<0.05?e (NAe4 -a1641.4+2.932.1+2.1<0.0524.6+2.2<0.0140.9+4.3>0.0542.4+2.8<0.0537.5+2.4 <0.05e?ioioeeoe)a1040.7+2.134.8+1.9<0.133.3+3.9>0.138.6+3.0>0.0543.4+1.9
<0.0541.6+2.9<0.1O-noi?ani?ea2419.1+2.018.9+2.3>0.0519.1+1.4>0.0522.3+3.
6>0.0520.8+3.1>0.0519.2+2.5>0.05(NAe8
-a1626.6+2.426.5+2.4>0.0525.5+2.7>0.0524.8+1.5>0.0524.8+1.6>0.0522.3+1.6
>0.05e?ioioeeoe)a1032.7+2.333.4+3.7>0.0532.3+4.3>0.0531.6+3.8>0.0531.6+2
.7>0.0532.8+3.4>0.05NAe4/NAe8a241.80+0.182.86+0.47<0.052.91+0.26<0.050.8 6+0.40>0.051.97+0.49>0.052.09+0.36>0.05a161.76+0.161.25+0.18<0.051.08+0. 13<0.051.68+0.19<0.051.74+0.17<0.051.73+0.12<0.05a101.24+0.131.10+0.14>0
.051.06+0.17<0.11.21+0.14>0.051.45+0.23>0.051.36+0.20<0.01 I?ei?oea: a- c aaoi?ioiieie ?aaeoe?yie aei iaa??aeueieo aioeaai?a a- aac aaoi?ioiieo ?aaeoe?e aei iaa??aeueieo aioeaai?a a- oa?oeeuei? ae?iee ??ai? NAe8+-e?ioioeeo?a o ianoaaeaieo ae?iie nooo?ai ia ci?ithaaeenue a aeeiai?oe? oeeeeo. Aea a a?oi? ae?iie c aaoi?ioiieie ?aaeoe?yie ??aaiue NAe8+ ia i?ioyc? anueiai oeeeeo aoa cia/ii ieae/ee, i?ae o iaie?aeieo ae?iie aac iaa??aeueiiai aaoi?ioi?oaoo oa o caei?iaeo ae?iie. Oea na?ae/eoue i?i iaoiaaiaoe/io ?ieue cieaeaiiy e?eueeino? O-noi?ani??a a ?icaeoeo aaoi?ioiiiai o?aaeaiiy y?/ieea. Aea/aiiy ooieoe?iiaeueiiai noaio O-e?ioioeeo?a a aeeiai?oe? iaino?oaeueiiai oeeeeo o ianoaaeaieo ae?iie iieacaei, ui iaea?eueo ae?aaeai? ci?ie oeueiai iieacieea oa?aeoa?i? aeey ae?iie c aaoi?ioiieie ii?ooaiiyie. Oae o?eueee a oe?e a?oi? niinoa??aa?oueny cia/ia cieaeaiiy ooieoe?iiaeueii? aeoeaiino? O-e?ioioeeo?a ia 0-aeaiue oa ia 21-e aeaiue oeeeeo ii??aiyii c 8-i aeiai (21,0+4,9 % ? 18,7+3,3 % i?ioe 32,8+5,1 %). Aiae?c ai?iiiaeueiiai oiio a aeeiai?oe? iaino?oaeueiiai oeeeeo o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino?, i?iaaaeaiee a caeaaeiino? a?ae aaoi?ioiieo ?aaeoe?e aei iaa??aeueieo aioeaai?a iieacaa, ui o ae?iie c aaoiaioeo?eaie aei no?oeoo? y?/ieea iaea i?noea i?eai?/aia i?iaeoeoe?y i?iaanoa?iio, ui ii/eia? i?iyaeyoeny aaea c 0 aeiy ia??iaoeyoi?iiai ia??iaeo ( 3,08+ 0,87 iae/ie i?ioe 5,13+1,1 iae/ie). Iniaeeai aaeeea iaaeinoaoi?noue i?iaanoa?iio aeyaeaia ia e?iaoeue oeeeeo, oiaoi ia 21-e aeaiue (16,3+3,6 iae/ie ? 12,8+2,6 iae/ie), eiee a a?oi? ae?iie aac aaoi?ioiieo ?aaeoe?e aiia aoea iaeneiaeueiith (29,5+3,1 iae/ie ? 30,0+6,4 , a?aeiia?aeii). Aeyaeaia cia/ia iaaeinoaoi?noue i?iaeoeoe?? ?ai?iaeoeoeaieo a?ee?a, ??12 oa ??14, a a?oi? ae?iie c aaoi?ioiieie aioeiaa??aeueieie ?aaeoe?yie ( Iae. 1). Ai?no aaoiaioeo?e aei ZP niinoa??aa?oueny ia an?o oacao iaino?oaeueiiai oeeeeo ? eieeaa?oueny a oeo?ao a?ae 1:4 aei 1:512. Aea iai?oaeai?noue aaoi?ioiieo ?aaeoe?e iineethaaeanue a ?? iieiaei? oeeeeo, ii/eiath/e c +1 aeiy. I/aaeaeii, oea iiaeia iia'ycaoe c iaoeyoe??th, ?ic?eaii no?iee oie?eoea ? iieaaoaiei eiioaeoii aioeaai?a ZP c ?ioiieiiiaoaioieie ee?oeiaie. I?iaaaeaiee ia?iee ei?aeyoeaiee aiae?c iieacaa ?nioaaiiy neeueiiai cai?ioiiai ca'yceo i?ae ??aiyie ?ai?iaeoeoeaiiai a?eeo ??14 c oeo?ii aaoiaioeo?e aei ZP (r=-0,873, ?<0,01). Oiaoi iecueeee ??aaiue ??14 oee?eoeyoe?? ? i?iaieoth/ei oaeoi?ii aeey ?icaeoeo /e aeey iineeaiiy i?iaeoeoe?? aaoiaioeo?e aei ZP. Oaeei /eiii, i?iaaaeaia aeine?aeaeaiiy ci?i ?ioiieia?/ieo iieaciee?a a aeeiai?oe? iaino?oaeueiiai oeeeeo na?ae/aoue i?i oa, ui aiie caciathoue cia/ieo ci?i ia i?ioyc? oeeeeo. Iaea?eueo ae?aaeai? ci?ie a?aeaoaathoueny a ia??iaoeyoi?iiio ia??iae?, a naia, a aeaiue iaoeyoe??, eiee o caei?iaeo ae?iie cia/ii cieaeo?oueny ??aaiue O-oaeia??a ? eiao?oe??ioa Oo/On. Oea iia'ycaii c iaiao?aei?noth noai?aiiy wmetafile8? ???4?? ?&????????&? ?yyyy????Word?Microsoft Word??? ??????? ;~???u?????????????I???Courier New?I????-?????????ue??yyy??????-? ???!??? ?en.1. ??ai? ?ai?iaeoeoeaieo a?ee?a (??12, ??14) a aeeiai?oe? iaino?oaeueiiai oeeeeo o iaie?aeieo ae?iie c aaoi?ioiieie ?aaeoe?yie aei iaa??aeueieo aioeaai?a oa aac ieo, a?aei.% caaaeueiiai ?ioiinoi?aneaiiai oiio a oie /an, eiee iiaeeeaa caie?aeiaiiy, c iaoith iiia?aaeaeaiiy aa?an?? i?ioe nia?iaeueieo aioeaai?a oa, yeui caie?aeiaiiy a?aeaoeiny, a?aeoi?aiaiiy caie?aeiaii? yeoeaee?oeie, yea ua ia ciaoiaeeoueny i?ae caoenoii oaoi-ieaoeaioa?iiai eiiieaeno, ianoi?iiaaiiai ia oeae /an. Iniiaiei i?ia?aeiei oaeoi?ii noai?aiiy ?ioiinoi?aneaiiai ioi/aiiy ? iioeiaeueiee ai?iiiaeueiee oii. Iaie iieacaii, ui o ae?iie c aaoi?ioiiei ii?aaeaiiyi ZP oa ai?iiiii?iaeoeoth/eo no?oeoo? y?/ieea - a?aioeueicieo ee?oei, cia/ii i?eai?/aia i?iaeoeoe?y i?iaanoa?iio, ?ioiinoi?aneaia ?ieue yeiai aaea aeiaaaeaia. Iaaeinoaoi?noue oi?ioaaiiy ?ioiinoi?aneaiiai oiio aeeeeeaia ia eeoa aeao?oeeoii i?iaanoa?iio, a e cieaeaieie ??aiyie ?ai?iaeoeoeaieo a?ee?a ??12 oa iniaeeai ??14, ui a?ae?a?athoue ?ieue aiaeiaaiieo ?ioii?aaoeyoi??a ?ai?iaeoeoeaiiai i?ioeano. O ae?iie aac aaoi?ioiieo ?aaeoe?e aei no?oeoo? y?/ieea i?iaeoeoe?y oeeo a?ee?a ciaoiaeeoueny ia aenieiio ??ai? ?, ine?eueee aiia ? ai?iiiicaeaaeiei i?ioeanii, iia'ycaia c ii?iaeueiei ooieoe?iioaaiiy y?/ieea. I?e aaoi?ioiiiio o?aaeaii? iaa??aeueieo no?oeoo? ii?ooo?oueny ia eeoa i?iaeoeoe?y i?iaanoa?iio, aea ?, aiane?aeie iaaeinoaoiueiai noeioethth/iai neaiaeo, cieaeo?oueny i?iaeoeoe?y ?ai?iaeoeoeaieo a?ee?a. Aea iiaeia neacaoe, ui iaaeinoaoi?noue ai?iiiaeueiiai neaiaeo ia ? ?aeeiith i?e/eiith cieaeaiiy neioaco ??12 oa ??14. Iaaeinoaoi?noue i?iaeoeoe?? ?ioiinoi?aneaieo ?ai?iaeoeoeaieo a?ee?a a naith /a?ao ? oaeoi?ii, ui i?aeneeth? iai?oaeai?noue aaoi?ioiieo ?aaeoe?e oa ni?ey? i?aeaeuaiith oeo?o aaoiaioeo?e aei ZP, caieeath/e, oaeei /eiii, oeaia eiei aaoi?ioiiiai o?aaeaiiy y?/ieea. O oai?eo c ii?aeiaieie oi?iaie iaie?aeiino?, ia? i?noea cia/ia ii?ooaiiy ooieoe?iiaeueiiai noaio a?iio?ca?ii-y?/ieeiai? nenoaie. Eeoa o ae?iie, ye? oai??thoue o?oaiith ? ia?eoiiaaeueiith iaie?aei?noth (? ee?i?/ia a?oia) nae?aoe?y noaoaaeo ai?iii?a iaeaea ia a?ae??ciy?oueny a?ae nae?aoe?? o ae?iie c iaii?ooaiith ?ai?iaeoeoeaiith ooieoe??th, a naia, caa??aa?oueny iaoeyoi?iee i?e ano?aae?ieo, c ianooiiei eiai niaaeii, noaa?e?coth/enue ia 21-23 aeaiue oeeeeo, ? aeaioaci?noue nae?aoe?? i?iaanoa?iio c i?eii ia 21-23 aeaiue oeeeeo, oiaoi a ia??iae ?icea?oo "aeiaoiai o?ea". O ieo caa??aa?oueny oeeee?/i?noue a aeae?eaii? aiiaaeio?iiieo ai?iii?a ? iacia/ia cieaeaiiy i?eo EA ? ONA a ia??iaoeyoi?iee ia??iae, ui na?ae/eoue i?i ooieoe?iiaeueiee oa?aeoa? ci?i aiiaaeio?iiii? ooieoe?? a?iio?ca. O oai?eo aea OCIANI ii?aeioaaany c niaeeiaith oai?iaith i?aai?a iaeiai oaco, aoi?eiiei neiae?iiii iie?e?noicieo y?/iee?a (?? a?oia) ai?no ano?aae?ieo ? i?iaanoa?iio aoa cia/ii ieae/ei ? iinea iiiioiiiee oa?aeoa?. Cieaeaia nae?aoe?y noaoaaeo ai?iii?a aoea iaaeinoaoiueith aeey ia??iaoeyoi?iiai aeeeaeo EA ? o oaeeo oai?eo ia ianooiaea iaoeyoe?y. Aeey ieo oa?aeoa?ii iiiioiii?noue aeae?eaiiy ye EA oa ? ONA a on? oace iaino?oaeueiiai oeeeeo. O iaie?aeieo ae?iie c NIEss, AA a ii?aeiaii? c OCIA niinoa??aaeanue iiiioiii?noue a aeae?eaii? ano?aae?ieo a e?ia?, ??cea iaaeinoaoi?noue i?iaanoa?iio ia 22-23 aeaiue oeeeeo, iniaeeai o ae?iie c NIEss, i?aeaeuaia eiioeaio?aoe?y EA, ONA ia i?ioyc? anueiai iaino?oaeueiiai oeeeeo. O oai?eo, aea iaie?aei?noue aeieeaea ia oii? OCIA a ii?aeiaii? c OI ( V ee?i?/ia a?oia) a?aei?/aii ??cea i?aeaeuaiiy aacaeueiiai ??aiy ano?iaai?a c a?aeiinii iecueeei ??aiai i?iaanoa?iio. Ne?ae cacia/eoe, ui ii?ooaiiy a?iioaeaii-a?iio?ca?ii? nenoaie o oai?eo c o?a?ii?iiith iaoee a ii?aeiaii? c OCIA iaaaoeaii aieeaathoue ia i?ioeane ?ai?iaeoeoe?? ? iaaoaathoue oa?aeoa?o naiino?eiiai caoai?thaaiiy. I?i oea oaeiae na?ae/eoue a?aenooi?noue aaeueioth/i? ae?? noaoaaeo ai?iii?a ia aiiaaeio?iii?. I?i no?oeoo?ii-ooieoe?iiaeuei? ci?ie aiaeiiao??th ie noaeeee ii aeoeaiino? oa?iaio?a aeeoaeueii? nenoaie (IAAeI-aeaa?ae?iaaiace, oeeoio?iiieneaeace, IAAeI-?aaeoeoace, noeoeeiao-oeeoio?iiieneaeace, noeoeeiao-aeaa?ae?iaaiace). I?iaaaeai? iaie aeine?aeaeaiiy iieacaee, ui a aiaeiiao??? ae?iie c iaii?ooaiith ?ai?iaeoeoeaiith ooieoe??th ia?aaaaeathoue i?ioeane aa?iaiiai ieeneaiiy. Ia oea aeacothoue aenie? iieacieee aeoeaiino? oa?iaio?a a IAAeI-aeaa?ae?iaaiacieo (IAAeI-AeA) oa oeeoio?iiieneaeacieo ?aaeoe?yo. Ii??aiyeueiee aiae?c io?eiaieo aeaieo aeyaea, ui ??aaiue IAAeI-?aaeoeoace aeinyaaa 21,7 % a?ae oaeaeeino? o?ainii?oo a?aeiiaethth/eo aea?aaeaio?a IAAeI-aeaa?ae?iaaiace. O ae?iie, aea o?ii?/iee caiaeueiee i?ioean aai?oae?e ii?aeioaaany c niaeeiaei i?ioeanii ? aoi?eiiei neiae?iiii i?ie?e?noicieo y?/iee?a, niinoa??aaeanue cia/ia ?ioaineo?eaoe?y aeaeo?io?ainii?oieo i?ioean?a a aiaeiiao??? ii??aiyii c ?o ia?aiao?aie a eiio?ieuei?e a?oi?. Inoaii? i?aeoaa?aeaeo?oueny i?aeaeuaiiyi a 4,5 ?ace aeoeaiino? IAAeI-aeaa?ae?iaaiace a aiaeiiao??? (0,521+0,117 i?ioe 0,115+0,054 ieiieue IAAeI - ia a?eeo oa.) ? a i?aeaeuaii? aaee/ei noeoeeiaoaeaa?ae?iaaiace a 1,7 ?ace. I?iaaaeaiee aiae?c, iai/ii aena?oeth? ?iceii?aeeiiaai?noue ie?aieo ae?eyiie aeaeo?io?ainii?oiiai oeyoo a aiaeiiao??? i?e o?ii?/ieo caiaeueieo i?ioeanao. Iiaeeeai naia ?icaaeainiaai?noue a aeai?e nenoai? ? iaei??th c i?e/ei cieaeaiiai aia?aaoe/iiai iioaioe?aeo aiaeiiao??th oa ii?ooaiue a iueiio oiia aeey i?aeaoe?? caie?aeiaii? yeoeaee?oeie. Noiniaii oai?eo ??? ee?i?/ii? a?oie, oi a ?o aiaeiiao??? ia?aaaaeaee i?ioeane aa?iaiiai ieeneaiiy, ? aeoeai?noue IAAe I-aeaa?ae?iaaiace neeaea 0,116+0,051 ieiieue IAAe I ia a?eea oa., IAAe I-oeeoio?ii-n-?aaeoeoace 0,021+0,003 ia a?eea oa., noeoeeiao-n-?aaeoeoace - 0,260+0,36 ieiieue-oeeo.n.ia a?eea oa., noeoeeiao-aeaa?ae?iaaiace ieiieue ia a?eea oa. ? oeeoio?iiieneaeace 1,221+0,100 ieiieue oeeo.n.ia a?eea oa. i?ioe oeeo aea iieaciee?a a eiio?ie?, a?aeiia?aeii 0,115+0,054 ; 0,025+0,005; 0,58+0,031; 0,320+0,067; 1,231+0,190 (P>0,05).

Iniaeeaino? niaeo?a iaeo?aeueieo e?i?ae?a ? oinoie?i?ae?a o ae?iie
c ii?aeiaieie oi?iaie iaie?aeiino? aea/aee a ne?iaaooe? e?ia?, iaia?aiao
a?eo?ioeeo?a ? aiiiaaiaoao aiaeiiao??th.

A ca’yceo c a?aenooi?noth noaoenoe/ii? ??cieoe? i?ae iieacieeaie ii
ee?i?/iei a?oiai iiaeaeueoa aeeeaaeaiiy iaoa??aeo aoaea i?ae ae?ieaie
c iaii?ooaiith ?ai?iaeoeoeaiith ooieoe??th ? ii?aeiaieie oi?iaie
iaie?aeiino?.

Iaie a?aei?/aii nooo?aa cieaeaiiy ai?noo oinoie?i?ae?a a
ne?iaaooe? e?ia? ? aiaeiiao??? o ae?iie c ii?aeiaieie oi?iaie
iaie?aeiino?.

Ii??aiyeueiee aiae?c aaee/ei o?aeoe?e iaeo?aeueieo e?i?ae?a a
oeaiei? aiaeiiao??th na?ae/eoue i?i nooo?a? ci?ie a eiioeaio?aoe??
oinoie?i?ae?a, a?eueieo aee?ieo eeneio ? o?eae?oea??ae?a. O oai?eo
ae?iie, i?e i?aeoe/ii, ??aiicia/iiio cieaeaii? ia?oeo aeaio c ieo (
a?aeiia?aeii ia 33,0 % ? 35,0 %) ??aaiue o?eae?oea??ae?a
ia?aaeuoaaa aiaeia?/i? iieacieee a oeaiei? aiaeiiao??th a eiio?ie? a 2,3
?ace. Ai?no noa?ei?a ye a?eueieo, oae ? ?o ao???a a aiaeiiao??? ia
ci?ithaaany.

Iaiao?aeii i?aee?aneeoe /?oeo ci?io aaee/ei a?aeiioaiiy a?eueieo
aee?ieo eeneio aei o?eae?oea??ae?a a aiaeiiao???, neeaaoe 4,97 aeey
ae?iie eiio?ieueii? a?oie ? eeoa 1,36 — aeey ae?iie c ii?aeiaieie
oi?iaie iaie?aeiino?. Iaei??th ?c i?e/ei cieaeaiiy caian?a aee?ieo
eeneio iiaea aooe ii?ooaiiy i?ioean?a ?o neioaco, yeee caaacia/o?oueny
a?aeiiaeaieie oi?iaie IAAeO aai ?ioaineaia ?o aeei?enoaiiy a
ooieoe?iioaaii? inoaii?o aeaio aia?aii?iaeoeoth/eo ae?eyieao
aeeoaeueiiai eaioethaa.

Ia iaoo aeoieo aeao?oeeo aee?ieo eeneio, yeee ie eiinoaoo?i,
ii?ooo? i?ioean i?iieeeeaino? iaia?aiieo no?oeoo?, ui ci?ith?
i?e?ia’yce?noue iaia?ai.

Iieacieeii, yeee oa?aeoa?eco? a cia/i?e i??? u?euei?noue iaia?aie,
? iiey?ia ni?aa?aeiioaiiy oieanoa?eio ? oinoie?i?ae?a.
?ic?aoiaai? iaie aaee/eie i?ioeaioieo ni?aa?aeiioaiue oeeo eiiiiiaio?a
e?i?ae?a aeicaieythoue aiai?eoe i?i ou?eueiai?noue iaia?ai, a
aeoiaey/e c oeueiai ? i?i cieaeaiiy o?ainii?oieo ?? ooieoe?e (
1,14+0,10 o caei?iaeo ae?iie ? 1,50+0,14 o ae?iie c ii?ooaiith
?ai?iaeoeoeaiith ooieoe??th, P<0,05). Aea/aiiy niaeo?o oinoie?i?ae?a o ianoaaeaieo ae?iie na?ae/aoue i?i oa, ui i?ae aieeaii caiaeueiiai i?ioeano a aai?oae?yo i?e ii?aeiaieo oi?iao iaie?aeiino? aeaa?aaeaoe?ei? ci?ie ??cieo ae?oea?ioinoie?i?ae?a i?ioiaeeee iaiaeiicia/ii a ??cieo a?ieia?/ieo oeaieiao. Oae, a NE niinoa??aaeinue cieaeaiiy a?eueo /ei a 2 ?ace oinoaoeaeii? eeneioe iniiaiiai eiiiiiaioo an?o oinoie?iae?a. Iaeiie/aiiy e?cioinoaoeae?eoie?io (EOO), oinoaoeae?e?iic?oa (O?) c oinoaoeae?ena??ia aeieeaei i?e iaeii/aniiio cieaeaii? oinoaoeae?eaoaiieai?io (OAA). A ieaciaoe/ieo iaia?aiao a?eo?ioeeo?a o ae?iie c caiaeueiei i?ioeanii niinoa??aaany ?ioee oa?aeoa? ci?i, yeee i?iyaeyany ciaioaiiyi ??aiy ne??iaii??e?io (NI) ? c?inoaiiyi oinoaoeae?eoie?io (OO) a?aeiinii aiaeia?/ieo aaee/ei o ae?iie c iaii?ooaiith ?ai?iaeoeoeaiith ooieoe??th. Cia/i? ci?ie ?a?no?oaaeenue ? a oeaiei? aiaeiiao??th. I?e oeueiio ie a?aei?/aee iaeiie/aiiy NI ? OO ia oii? cieaeaiiy ai?noo [O1+ON]. ?ic?aooiie aaee/ei ni?aa?aeiioaiiy OO ? NI a?aeia?acea c?inoaiiy ia?oiai ?c ieo a ne?iaaooe? e?ia? ? iaia?aiao a?eo?ioeeo?a o ae?iie c ii?ooaiith ?ai?iaeoeoeaiith ooieoe??th (3,38+0,13 a?aei.% ? 8,52+0,30 a?aei.% a?aeiinii 2,70++0,12 a?aei. % ? 3,28+0,3 a?aei. % a eiio?ie?, ?<0,05). A oeaiei? aiaeiiao??th ni?aa?aeiioaiiy oeeo eiiiiiaio?a ia ci?ithaaeinue. A oeaiei? aiaeiiao??th o ae?iie c iaie?aei?noth a?aei?/aeinue i?aeaeuaiiy ieoiii? aaae ciai?oiuei-iaia?aiieo oinoie?i?ae?a, ye? aeinyaaee 1,66+0,25 i?ioe 0,95+0,15 a eiio?ie?, ui i?eaiaeeoue aei aaeueioaaiiy aeoeaiino? oa?iaio?a aeeoaeueiiai eaioethaa. Oaeei /eiii, caiaeueiee i?ioean aai?oae?e i?e ii?aeiaieo oi?iao iaie?aeiino? i?ecaiaeeoue aei cia/ieo ci?i iaoaaie?cio ae?oea?ie?i?ae?a, aecia/ath/eo i?e?iioi/aiiy iaia?aiica’ycaieo oa?iaio?a, i?e?ia'yce?noue iaia?aie ? ?? caeaoi?noue aei ?aaaia?aoe?? aia?a??. Io?eiai? aeai? na?ae/aoue i?i oa, ui iaei??th c i?e/ei iaie?aeiino? o ae?iie i?e caiaeueiiio i?ioean? aai?oae?e, ? ?iceii?aeeiiaai?noue aeoeaiino? oa?iaio?a aeeoaeueiiai eaioethaa, yea iaoiiaeaia aeenaaeainii e?i?aeieo eiiiiiaio?a a ee?oeiieo no?oeoo?ao, cie?aia, a neecia?e iaieiioe? iaoee. Aea/aiiy a?io?i?/ieo ia?aiao??a, ui oa?aeoa?ecothoue noai i?i- oa aioeieneaeaioii? nenoaie e?ia? ? aiiiaaiaoao aiaeiiao??th, aeyaeei nooo?a? ?o ci?ie, ye? iiaeooue aeeeeeaoe iaaaoeai? c?ooaiiy ye a ooieoe?iioaaii? oe?eeo i?aaiieo nenoai, oae ? a oi?ioaaii? oa ?aaoeyoe?? eiiiainaoi?ii-aaeaioaoe?eieo i?ioean?a a i?aai?ci? ae?iie c ii?aeiaieie oi?iaie iaie?aeiino?. O oai?eo c o?oaiith ? ia??oiiaaeueiith oi?iaie iaie?aeiino? a ii?aeiaii? c aoi?eiiei NIEss a NE aaea?/? c?inoaa ??aaiue iaeiiiaiai aeeaeueaeaa?aeo ii??aiyii c aiaeia?/ieie eiai aaee/eiaie o caei?iaeo ianoaaeaieo. Oaea iaeiie/aiiy iaoaaie?oo noi?iaiaeaeoaaeinue ia?aeaeueiei cieaeaiiyi (aei 40,0 %) eiioeaio?aoe?? a?ae?iia?aeen?a e?i?ae?a. A?aei?/aia ciaioaiiy ai?noo a?ae?iia?ae?n?a, i/aaeaeii, iia'ycaia ? c c?inoaiiyi iiaeaeueoi? ?o iaoaaie?caoe?? a i?ioeanao a?eueii-?aaeeeaeueiiai ieeneaiiy. O ae?iie c NIEss oa OI a ii?aeiaii? c OCIA aeyaeyany iaeiaeiai i?aeaeuaiee ??aaiue iaeiiiaiai aeeaeueaeaa?aeo, a oaeiae i?ioean?a ia?aieeneaiiy e?i?ae?a. O ae?iie c AA ?a?no?oaaeanue iaeaeua eiioeaio?aoe?y IAeA( 28,12+6,84 ieiieue/a a?eeo i?ioe 50,77+3,06 a ieiieue/a a?eeo a eiio?ie?). Aea/aiiy ia?aiao??a aioeieneaeaoii? nenoaie o ianoaaeaieo ae?iie aeyaeei iii?oia cieaeaiiy oiiaeo a?aeiiaeaiiai aeooao?iio, ui iiaea iaoiiaethaaoe niaae ieenii-a?aeiiaiiai iioaioe?aeo a i?aai?ci?, c iaeiiai aieo, aaeueioaaiiy aeoeaiino? nenoaie aioe?aaeeeaeueiiai caoenoo - c ae?oaiai. Ae?aaeaia iaae?iiy aeoeaiino? eaoaeace, aeooao?ii-So?ainoa?ace oa iniaeeai noia?ieneaeaeeniooace o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? i?aeaeuo? a??ia?aei?noue ?icaeoeo aeac?ioaa?aoe?eieo ci?i, ye? ia iaoo aeoieo, iaoiiaeththoue o?ii?caoe?th iaoieia?/iiai i?ioeano oa iniaeeaino? eiai i?io?eaiiy. Ia?aeaeueii i?iaaaeaiee iaie aiae?c ?acoeueoao?a IIE a oeaiei? aiaeiiao??th ianoaaeaieo oai?eo na?ae/eoue i?i iaeiiiai?aaeaiee oa?aeoa? eiai ci?i. sse ? a e?ia? oai?eo, a aiaeiiao??? c?inoaea e?euee?noue eii'thaao?a iaiane/aieo aee?ieo eeneio, iniaeeai o ae?iie II oa IV a?oi. I?eaa?oa? oaaao a?aenooi?noue aiaeia?/ieo ci?i o ae?iie V a?oie. Iiaeeeai oea iia'ycaii c i?io?eaiiyi aeoeaieo i?ioean?a a a?eueo aeeaieeo oa?ao oeaieie i?iiao??th aai ?o ni?yioaaiiyi a i?noeyo acyooy c?ace?a aeey aeine?aeaeaiiy. I?e oeueiio ye ? a e?ia? niinoa??aaeinue cia/ia i?eai?/aiiy ooieoe?iiaeueiiai noaio aioe?aaeeeaeueii? nenoaie. Iaeieae/ee ??aaiue aeooao?ii?aaeoeoace niinoa??aaany o ae?iie c neiae?iiii iie?e?noicieo y?/iee?a a ii?aeiaii? c OCIANI (III ee?i?/ia a?oia) , a iaeaeuee o ae?iie c o?a?ii?iiith iaoee ? OCIANI (V ee?i?/ia a?oia). Aeoeai?noue aeooao?ii-S-o?ainoa?ace aoea cia/ii ieae/ith o ae?iie IV-V ee?i?/ieo a?oi a ii??aiyii? c ae?ieaie I-III a?oi. A?aeiia?aeue c aieo aeooao?iiiacaeaaeii? nenoaie aioe?aaeeeaeueiiai caoenoo aoea i?yii i?ioeeaaeiith aei ci?i aeoeaiino? aeooao?ii-caeaaeiiai eiiieaeno ? i?iyaeyeanue c?inoaiiyi eaoaeacii? ?aaeoe?? o ae?iie III ? IV ee?i?/ieo a?oi ii a?aeiioaiith aei ? ? ??, iaci?ithth/eo o V a?oi?; i?aeaeuaiiyi aeoeaiino? noia?ieneaeaeeniooace, iniaeeai o ae?iie IV a?oie. Oaeei /eiii, aeyaeai? ci?ie o ae?iie c iaie?aei?noth na?ae/aoue i?i aeoeaaoe?th i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a ia oii? ?icaaeainiaaii? ?aaoeyoe?? oa i?eai?/aiiy nenoaie aioeieneaeaioiiai caoenoo. I?e oeueiio, oa?aeoa? anoaiiaeaieo ci?i a e?ia? ia a?aeia?aaea? ?o iai?aaeaiino? a oeaiei? aiaeiiao??th. Iaea?aeai? ?acoeueoaoe aeicaieythoue i?eioneaoe, ui iaeiei c aaaeeeaeo iaoiaaiaoe/ieo iaoai?ci?a i?e aeai?e iaoieia?? ? ?i?oe?aoe?y i?ioean?a ia?ieneaeaoe?? e?i?ae?a oa iia'ycaiee c iath iaaaoeaiee aieea a?eueieo ?aaeeeae?a ? i?iaeoeo?a ia?aieeneaiiy ia ooieoe?iioaaiiy oa iaoaaie?ci aioo??oiueiee?oeiieo no?oeoo?. Ia aeeeth/aii, ui aeeeeeai? aenieei ??aiai IIE ci?ie a no?oeoo?? a?ieia?/ieo iaia?ai, ?o i?iieeeeaino? ? ooieoe?iiaeueieo aeanoeainoae iaoiiaeththoue iecueeo aoaeoeai?noue no/anieo oa?aiaaoe/ieo caoiae?a aei a?aeiiaeaiiy ooieoe?iiaeueii iaiiaiioe?iieo ee?oei aiaeiiao??th. Inoaii? aeeeoo? iaiao?aei?noue i?aeai?o oa iaia'yceiaiai aeeth/aiiy aioeieneaeaio?a aei e?eoaaeueieo eiiieaen?a. Iaie i?iaaaeaia oeeoiaaiaoe/ia oa oeeoiii?oieia?/ia oa?aeoa?enoeea iioeeo?a o ianoaaeaieo ae?iie a i?e?iaeiueiio ? noeioeueiaaiiio iaino?oaeueiiio oeeee?. I?e aea/aii? iioeeo?a c aio?aeueieo oie?eoe?a, iaea?aeaieo c o?aaiaio?a y?/iee?a o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino?, c o?eaaeei ia?aa?aii caiaeueiiai i?ioeano a i?e?iaeiueiio iaino?oaeueiiio oeeee? aeyaeaia ii?oieia?/ia aaoa?iaaii?noue ye ii i?eaeeoo?aei iciaeai, oae ? ii noaio yaea?iiai iaoa??aeo, a oaeiae aenieee a?aenioie iioeeo?a c iciaeaie aeaaaia?aoe?? yaea?iiai iaoa??aeo (67,4 % i?ioe 28,0 %). Oaeee aenieee a?aenioie iioeeo?a c iciaeaie aeaaaia?aoe?? yaea?iiai iaoa??aeo (67,4 % i?ioe caaaeaieo 28,0 %) iiaeia iiynieoe ii?ooaiiyi oie?eoei- ? iiaaiaco o ae?iie c o?eaaeei i?io?eaiiyi caiaeueiiai i?ioeano, ui a naith /a?ao, aeeeeea? ii?ooaiiy ai?iiiaeueiiai oiio a i?aai?ci? ae?iee. Oea iiaea aooe iaei??th ?c i?e/ei a?aenooiino? aaa?oiino? o ae?iie c a?aeiiaeaiith i?io?aei?noth yeoeaaiae?a, a oaeiae iaaaoeaii aieeaa? ia io?eiaiiy iiceoeaiiai ?acoeueoaoo i?e i?iaaaeai? aeno?aei?ii?aeueiiai caie?aeiaiiy. I?e aeaeo?iiiii?e?ineii?/iiio aeine?aeaeaii? iioeeo?a c aio?aeueieo oie?eoe?a y?/iee?a ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? iieacaii, ui eeoa oeueo?ano?oeoo?a oeeoiieacie (38,9 %) iioeeo?a a?aeiia?aea? aoaeia? ii?iaeueieo iaaeic??eeo iioeeo?a ia noaae?? aeeieioaie. O a?eueoino? c aeine?aeaeaieo iioe?oea (61,1 %) ia oeueo?ano?oeoo?iiio ??ai? aeyaeai? ii/aoeia? aai a?eueo ae?aaeai? iciaee ao?ac??, a oaeiae yai? aeaaaia?aoeai? ci?ie a oeeoiieaci? oa ioi/oth/eo iioeeee?oeiao eoioethno. Iaie i?iaaaeaii oeeoiaaiaoe/iee aiae?c iioeeo?a c ae??aieo oie?eoe?a o ae?iie a noeioeueiaaieo iaino?oaeueieo oeeeeao. 1-a noaia - i?ioac? 6000 iae. ia 12-13 aeaiue iaino?oaeueiiai oeeeeo ca 34-36 aiaeei aei iia?aoe??; 2-a noaia - eeinoeeueaaa?o ii 50 ia c 5 ii 9 aeaiue oeeeeo ? i?ioac? 6000 iae. ca 34-36 aiaeei aei iia?aoe??; 3-a noaia - ooiaaii - ii 75-150 ia c 5 ii 9 aeaiue oeeeeo ? i?ioac? ca 34-36 aiaeei aei iia?aoe??; 4-a noaia - ia?aae iia?aoe??th i?iaiaeeeinue aioo??oiuei-noaeeiia ii?ii?ithaaiiy aae?e-iaiiiaei eaca?ii ia i?ioyc? 30 oaeeei a aeaiue c 5-8 ii 9-13 aeaiue iaino?oaeueiiai oeeeeo. ?acoeueoaoe aeine?aeaeaiue iieacaee, ui iaee?au? ?acoeueoaoe iaea?aeai? i?e noeioeyoe?? iaoeyoe?? aae?e-iaiiiaei eaca?ii (AEIE). Ii?iaeuei? iioeeoe iaea?aeai? a 63,6 % aeiaaee?a, a oie /an ye i?e ?ioeo noaiao ii?iaeuei? iioeeoe iaea?aeai? a 55,5 28,6 % aeiaaee?a. A ?acoeueoao? OC-iii?oi??iao ca oie?eoeiaaiacii anoaiiaeaii, ui o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? a niiioaiiiio iaino?oaeueiiio oeeee? o 73,3 % a?aei?/aeinue niia?eueiaiiy ?inoo aeii?iaioiiai oie?eoea, ciaioaiiy eiai ?ici???a, oi?ioaaiiy oeueo?acaoeiaeo iciae aoi?eiiiai iie?e?noico y?/iee?a. Aeey iaoaiaoe/ii? ia?iaee ia?aeiieo iaaee/ieo aeaieo oa noai?aiiy aeai?eoio i?iaiicoaaiiy ia iniia? ao?aeiiai aeieoiaioo (oi?iae?ciaaii? iaaee/ii? ea?oe) aoea noai?aia aaca aeaieo ia IIAI ?AI ?N/AO. No?oeoo?a aace aeaieo a?aeia?aaea? no?oeoo?o ?noi??? oai?iae ? i?noeoue iiey, ui a?aeiia?aeathoue ieoaiiyi oi?iae?ciaaii? iaaee/ii? ea?oe (ianii?oi? aeai?, nea?ae, aiaiiac oai?iae, aiaiiac aeeooy, oe?aeeea? cae/ee, iieacieee iaino?oaeueii? oa aaia?aoeaii? ooieoe??, aeai? caaaeueiiai ianoaaeaiiy, a?iaeieia?/iee noaoon, eieueiineii?y, aacaeueia oa?iiiao??y, eieueiioeeoieia?y, OCAe, AeNAIN, nia?iia?aia /ieia?ea, iiaaiiiaeuea?ia?ao?y, e?ai?ia?ao?y, AN, EN, i?iaaaeaia e?eoaaiiy o a?aeae?eaii?, ae?aaiic, a?io?i?/i? aeine?aeaeaiiy, ai?iiiaeuei? aeine?aeaeaiiy, ?aieia?/i? aeine?aeaeaiiy, ?ioiieia?/i? aeine?aeaeaiiy, a?aeaeaeaii? ?acoeueoaoe e?eoaaiiy). A?aoiaoth/e oa, ui iaeia’?eoeai?oei e?eoa???i aoaeoeaiino? aoaeue-yeiai iaoiaeo e?eoaaiiy iaie?aeiino? ? ianoaiiy aaa?oiino? oa ia?iaeaeaiiy aeeoeie ?ic?iaeaiee iaie aeai?eoi iiaeiai aeey eiie?aoii? ae?iee c iaaiith cacaeaeaa?aeue anoaiiaeaiith a??ia?aei?noth aeae?aoe iaeia c aeaio i?iaiinoe/ieo ??oaiue: ia?oa - "Aaa?oi?noue ianooieoue", ae?oaa - "Aaa?oi?noue ia ianooieoue". *an oia?aaeaeaiiy (i?ii?aeie /ano, ui a?aeae?ey? iiiaio ia?aaeaa/aiiy a?ae iiiaioo ianoaiiy ia?aaeaa/aiiai aeiaaeeo) aeey aeaiiai aeai?eoio i?iaiicoaaiiy noaiiaea 3 ?iee. C iaoith i?enei?aiiy oa ni?iuaiiy i?ioeaaeo?e i?eeiyooy i?iaiinoe/iiai ??oaiiy (aac nooo?aiai cieaeaiiy eiai oi/iino? oa yeino?) aoee a?ae?a?ai? 25 iaea?eueo ?ioi?iaoeaieo iciae, noia?ia ?ioi?iaoeai?noue eiaeii? c yeeo aoea a?eueo 10,0 % a?ae iaea?eueoi? ?ioi?iaoeaiino? (I=9,886). Ia aoai? ae?aaiinoeee aecia/aany 21 iieaciee ? o?eueee 4 - c a?aooaaiiyi i?iaaaeaiiai e?eoaaiiy. Aei ?a/? c oeeo /ioe?ueio oaeoi??a iaeei ("A?aeiiaeaiiy, i?io?aei?noue iaoeiaeo o?oa") iaa iaeaeuo ?ioi?iaoeai?noue. I?iaiinoe/ia ??oaiiy a?aeiinii ianooieaiiy aaa?oiino? iiaea aooe i?eeiyoa ia i?aenoaa? ?acoeueoao?a ianoaaeaiiy (aiaiiac, a?iaeieia?/iee iaeyae, AeNAIN, AN). Aea ?ioi?iaoeai?noue eiaeiiai c a?ae?a?aieo iaie 25 oaeoi??a iaioa iaiao?aeiiai ae?aaiinoe/iiai ii?iao ? oiio aeiaeai c ieo ia iiaea naiino?eii aac a?aooaaiiy ?ioeo oaeoi??a ae??ooaaoe i?iaiic. O?eueee niieo/aiiy aeae?eueeio iieaciee?a aeicaiey? aeianoe i?iaiinoe/ia ??oaiiy i?i a??ia?aei?noue canooieaiiy aaa?oiino?. C ?ioiai aieo, iaea?eueo aeniea ?ioi?iaoeai?noue iieacieea "A?aeiiaeaiiy, i?io?aei?noue iaoeiaeo o?oa" i?aeoaa?aeaeo? i?ia?aeio ?ieue iaoeiaeo o?oa aeey iiaeaeueoiai canooieaiiy aaa?oiino?. Aea i?iaaaeaiee iaoaiaoe/iee aiae?c iieacaa, ui iiaia i?io?aei?noue iaoeiaeo o?oa ? iaiao?aeiith aea ia ? aeinoaoiueith oiiaith canooieaiiy aaa?oiino?. Oea iiaeia ?icoe?ithaaoe ye iai?yia i?aeoaa?aeaeaiiy cia/ii? ?ie? ii?aeiaieo (?ioiieo, aiaeie?eiieo oa ?ioeo) oaeoi??a aaaaoieiiiiiaioii? ?ai?iaeoeoeaii? nenoaie aeey ?? oni?oii? ?aae?caoe??. Iine?aeiaia oe?eani?yiiaaia aea/aiiy i?e/ei ? ?ice?eooy iaoai?ci?a iioeiaeaeaiiy ?ai?iaeoeoeaii? ooieoe?? i?e ii?aeiaieo oi?iao iaie?aeiino? aeicaieeei iai iaa?oiooaaoe iaoiaaiaoe/io aeeoa?aioe?eiaaio oa?ai?th. I?eeiath/e aei oaaae oa, ui iaia'yceiaei /eiieeii o ianoaaeaieo oai?eo aoa OCIA, ia ia?oeo aoaiao canoiniaoaaeinue eiiieaenia oa?ai?y iai?aaeaia ia e?ea?aeaoe?th aeaea?aea ?ioaeoe??. Eiiieaenio i?ioecaiaeueio oa?ai?th c aeei?enoaiiyi ianiaoeeo?/ieo iaoiae?a caaino?aiiy o?ii?/iiai i?ioeano i?iaiaeeee iaeii/anii ? a /ieia?ea ? a ae?iee, c aeeth/aiiy a eiiieaen oa?ai?? aioeieneaeaio?a (ait "A"), ?ioiinoeioeyoi??a (iaoeeo?aoeee), aioea?noai?i?a, a?oai?i?a a?oie A1, N. C iaoith iaai?iiiaeueii? noeioeyoe?? iaoeyoe?? i?ecia/aee aioo??oiueiaaiia eaca?ia ii?ii?ithaaiiy e?ia? c 5 aeiy iaino?oaeueiiai oeeeeo ii 20 oaeeei eiaeiee aeaiue, ia i?ioyc? 5-7 aei?a. I?ney iiaiiai ee?i?ei-eaai?aoi?iiai ianoaaeaiiy, anoaiiaeaiiy cae-eth/iiai ee?i?/iiai ae?aaiico i?e a?aenooiino? aaa?oiino? i?ney i?iaaaeaiiai e?eoaaiiy ia i?ioyc? 2-3 i?nyoe?a ianooii? aoaie e?eoaaiiy aeey ianoaaeaieo a?oi aoee ??ci?. II aoai e?eoaaiiy aeey oai?eo I ? II ee?i?/ii? a?oi i?iaiaeeany /a?ac 2-3 i?nyoe? i?ney cae?i/aiiy ia?oiai ? aoa iai?aaeaiee ia iie?auaiiy aaiiaeeiai?ee, oeaieiiiai iai?io, i?e?ioee?eoeyoe?? a oeaieiao ? i?aaiao, a?aeiiaeaiiy ?ioiieo, ai?iiiaeueieo ? ia?aiaeo iaoai?ci?a ?aaoeyoe?? ? a?aeiiaeaiiy i?io?aeiino? iaoeiaeo o?oa. I?e iai?io?aeiino? iaoeiaeo o?oa ? ae?aaeaieo ia??ooaa?ieo c?iuaiiyo i?iaiaeeeanue o??o?a?/ia ?aaa?e?oaoe?y c iiaeaeueoith i?io?eaeoeeith niaeeiaiai i?ioeano. Ieanoe/i? iia?aoe?? i?iaiaeeeenue c aeei?enoaiiyi i?e?io??o?a?/iiai ?ino?oiaioa??th, o?aaiaoe/iiai oiaiiai iaoa??aeo ? iioe/ieo i?eeaae?a. Oai?ei III ee?i?/ii? a?oie i?e i?io?aeieo iaoeiaeo o?oaao i?iaiaeeeanue noeioeyoe?y iaoeyoe?? iaeiei ?c aeacaieo iaoiae?a. I?e a?aenooiino? aaa?oiino? ia i?ioyc? 6 i?nyoe?a oai?ei i?iaiaeeeanue o??o?a?/ia EN (?ic’?aeiaiiy niaeie i?aai?a iaeiai oaco, naeuei?iaie?c?n, ae?aoa?iieiaaoeyoe?y, - eaooa?ecaoe?y, a?iin?y y?/iee?a). I?e ii?aeiaii? NIEss c iai?io?aeieie iaoeiaeie o?oaaie - o??o?a?/ia ?aaa?e?oaoe?y (ieanoeea iaoeiaeo o?oa, eeeiiaeaeia ?acaeoe?y y?/iee?a, i?io?eaeoeee niaeeiaiai i?ioeano). Oai?ei IV ee?i?/ii? a?oie i?ecia/aee ia 6 i?nyoe?a e?eoaaiiy aiaeiiao??ico. I?e /anoeiai i?io?aeieo o?oaao - o??o?a?/ia eaia?ineii?y (naeuei?iaie?c?n, aaia?ecaoe?y aiaeiiao??i?aeieo aiaieu) ? i?e iai?io?aeieo iaoeiaeo o?oaao ? oieieaaeieo e?noao - o??o?a?/ia ao?o/aiiy. On?i ae?ieai V ee?i?/ii? a?oie i?iaiaeeeanue o??o?a?/ia ?aaa?e?oaoe?y (eiina?aaoeaia i?iiaeoii?y, aioeeaaoe?y o?a?iiaoicieo aoce?a, naeuei?iaiiaa??ie?c?n, naeuei?iainoii?y). Oaaeeoey 2 A?aeaeaeai? ?acoeueoaoe e?eoaaiiy o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? Iaoiaee ?aaa?e?oaoe??Ee?i?/iaeiina?aaoeai? (n - 98)o??o?a?/i? (n - 101) a?oiacaaaa?oi?eeia caaaa?oi?eecaaaa?oi?eeia caaaa?oi?eeaan./.%aan./.%aan./.%aan./.%?1644,42055,6844,51055,5??1458,31 041,71021,53278,5???1076,9323,11145,71354,3?V1150,21049,8436,3763,7V129, 5370,5563,7233,3ANUeIAI:5253,04647,03743,06457,0 Ei?aeoe?th aeyaeaieo ai?iiiaeueieo, ?ioiieia?/ieo, a?io?i?/ieo ci?i i?iaiaeeee aeeoa?aioe?eiaaii c o?aooaaiiyi ??aiy ii?ooaiiy, ii?aeiaiiy aeae?eueeio /eiiee?a o?eueee i?ney a?aeiiaeaiiy i?io?aeiino? iaoeiaeo o?oa ? e?ea?aeaoe?? ?ioeo aiaoii?/ieo ci?i noaoaaeo i?aai?a. I?ney a?aenooiino? aaa?oiino? ia i?ioyc? 6 i?nyoe?a oai?a iiaoi?ii ianoaaeoaaeanue ? i?e /anoeiai i?io?aeieo o?oaao ? ia??oiiaaeueiiio oaeoi?? i?iaiaeeeanue o??o?a?/ia eaia?ineii?y. I?e i?io?aeieo iaoeiaeo o?oaao, 2-oaciiio iaino?oaeueiiio oeeee? iiaoi?ii ianoaaeoaaany /ieia?e ? i?iaiaeeeenue aeine?aeaeaiiy ia iayai?noue aioenia?iaeueii? ?cinainea?e?caoe??. Ia ??cieo aoaiao e?eoaaiiy i?e iayaiino? aioenia?iaeueieo aioeo?e i?ecia/aeanue aeanainea?e?coth/a oa?ai?y, eiiaeii - oa?ai?y ia i?ioyc? 3 i?nyoe?a. A iiaeaeueoiio i?e a?aenooiino? aoaeoo iiae?oaeith ia?o iai?aaeyee ia ooo/io ?inai?iaoe?th nia?iith /ieia?ea aai aeiii?nueeith nia?iith. A?aeaeaeai? ?acoeueoaoe e?eoaaiiy ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? iaaaaeai? a oaae. 2. AENIIAEE 1. Na?aae i?e/ei iaie?aeiino? o ae?iie i?ia?aeia i?noea caeiathoue caiaeuei? caoai?thaaiiy aioo??oi?o noaoaaeo i?aai?a, ye? /anoi ii?aeiothoueny c ia?aeiiei ? aoi?eiiei neiae?iiii iie?e?noicieo y?/iee?a ( 12,4% ? 39,3%, a?aeiia?aeii), c aai?oaeueiei aiaeiiao??icii ( 29,1%) ? o?a?ii?iiith iaoee (9,2%). 2. Ii?aeiaiiy aeaio aai o?ueio oaeoi??a iaie?aeiino? i?ecaiaeeoue aei iaoyaeaiiy ee?i?/iiai ia?aa?ao caoai?thaaiiy, cao?oaeiy? aecia/aiiy iniiaii? ? noiooiuei? i?e/eie iaie?aeiino?, ui iaaaoeaii aieeaa? ia aea?? aaeaeaaoii? oe?eani?yiiaaii? oa?ai??. Aeeiai?/ia iine?aeiaia ianoaaeaiiy ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? c aeei?enoaiiyi o?aaeeoe?eieo ? no/anieo iaoiae?a ( ae?a?oaeueia noaeo?aoe?eia a?aeaiiao?inaeuei?iaia?ao?y, aia?ia?ao?y, eaia?ineii?y, a?noa?ineii?y) aeicaiey? ia o?eueee anoaiiaeoe aiaoii?/i? ? ooieoe?iiaeuei? ci?ie a iaooe?, o?oaao, y?/ieeao, aea ? aea? ciiao aecia/eoe iniiaio i?e/eio iaie?aeiino?, anoaiiaeoe nooi?iue ae?aaeaiino? niaeeiaiai i?ioeano, aecia/eoe eieae?caoe?th ? aeeaeio iioeiaeaeaiiy i?aaio, ui aaaeeeai i?e iiaeaeueo?e ?ic?iaoe? oaeoeee ei?aeoe?? aeyaeaieo ci?i. 3. O oai?eo c iaie?aei?noth ii?aeiaiiai aaiaco aeyaeythoueny iciaee ??ceiai ii?ooaiiy ?ioiieia?/iiai aiiainoaco, ye? i?iyaeythoueny aeao?oeeoii O- ? A-ee?oeiii? eaiee, aeen?ioiieiaoe?iai??th a ne?iaaooe? e?ia?, i?aeaeuaiiyi nae?aoi?iiai IgA, IgG, A, cieaeaiiyi e?cioeeio a oea?a?eaeueiiio neeco, a oie?eoey?i?e ? ia??oiiaaeuei?e ??aeeiao. Anoaiiaeaia ?icaaeainiaai?noue iieaciee?a ee?oeiiiai caaaeueiiai ? i?noeaaiai ?ioi?oaoo a a?ieia?/ieo ??aeeiao a aeeiai?oe? iaino?oaeueiiai oeeeeo, i?i ui na?ae/eoue a?aenooi?noue noi?an?? a ia??iaoeyoi?ee ia??iae, iaiao?aeii? aeey o?c?ieia?/iiai i?ioeano caie?aeiaiiy. 4. Aecia/aia ?ieue aioenia?iaeueii? ?cinainea?e?caoe?? a iaoiaaiac? iaie?aeiino?. Iieacaia iaiaeiicia/ia eiioeaio?aoe?y nia?i?iia?e?coth/eo aioeo?e a ??cieo a?ieia?/ieo ??aeeiao (N?AO aeyaeythoueny a 2 ?ace /ano?oa a ia??oiiaaeuei?e oa oie?eoey?i?e ??aeeiao i?ae a ne?iaaooe? e?ia?), ui na?ae/eoue i?i aaoiiiiio ?ieue ii?ooaiue ia??oa??eii? eaiee ?ai?iaeoeoeaii? nenoaie. 5. Anoaiiaeaii, ui o 31,5% ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? aeyaeai? aaoiaioeo?ea aei Zona pellunida yeoeaee?oeie, o 10,5% aei a?aioeueicieo ee?oei, i?e/iio, i?iaeoeoe?y ?o iia'ycaia c iecueeei ??aiai NAe4 ia ii/aoeo ? a e?ioe? iaino?oaeueiiai oeeeeo c iacia/iei i?aeaeuaiiyi a ia??iaoeyoi?iee ia??iae, a oie /an, ye o oa?oeeueieo ae?iie ai?no NAe4 ia? cai?ioith iai?aaeai?noue. O iaie?aeieo ae?iie c aaoi?ioiiei ii?aaeaiiyi y?/iee?a cia/ii i?eai?/aia i?iaeoeoe?y i?iaanoa?iio, cieaeai? ??ai? ?ai?iaeoeoeaieo a?ee?a ??12, ??14. 6. Ci?ie a?iio?ca?ii-aiiaaeii? nenoaie o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? iaiaeiicia/i? ? ciaoiaeyoueny a i?yi?e caeaaeiino? a?ae aeeaeie iioeiaeaeaiiy oiai /e ?ioiai i?aaio, iniiaiiai ae?aaiico, o?eaaeino? caoai?thaaiiy. Iaea?eueo ae?aaeai? ci?ie niinoa??aaeenue o ae?iie c o?ii?/iei caiaeueiei i?ioeanii a ii?aeiaii? c neiae?iiii iie?e?noicieo y?/iee?a, o?a?ii?iiith iaoee, aiaeiiao??icii. 7. Anoaiiaeaii, ui o ae?iie c iaii?ooaiith ?ai?iaeoeoeaiith ooieoe??th aia?aaoe/iee iioaioe?ae a aiaeiiao??? i?aeo?eio?oueny ca ?aooiie i?ioean?a aa?iaiiai ieeneaiiy, i?i ui na?ae/eoue aeniea aeoeai?noue oa?iaio?a a IAAeI-aeaa?ae?iaaiacieo oa oe?oio?iiieneaeacieo ?aaeoe?yo. O iaie?aeieo ae?iie ae?aaeaia ?iceii?aeeiiaeoeai?noue aeoeaiino? oa?iaio?a aeeoaeueiiai eaioethaa, yea iaoiiaeaia aeenaaeainii e?i?aeieo eiiiiiaio?a a ee?oeiieo no?oeoo?ao aiaeiiao??th, ui i?ecaiaeeoue aei cieaeaiiy aia?aaoe/iiai iioaioe?aeo a aiaeiiao??? oa iaaaoeaii aieeaa? ia i?aeaoe?th caie?aeiaii? yeoeaee?oeie. 8. Aeyaeai? ci?ie a e?ia?, oa a oeaiei? aiaeiiao??th o ae?iie c iaie?aei?noth ii?aeiaiiai aaiaco oa?aeoa?ecothoueny aeoeaaoe??th i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a ia oii? ?icaaeainiaaii? ?aaoeyoe?? oa i?eai?/aiiy nenoaie aioeieneaeaioiiai caoenoo. Oa?aeoa? anoaiiaeaieo ci?i a e?ia? ia a?aeia?aaea? ?o iai?aaeaiino? a oeaiei? aiaeiiao??th. 9. O ae?iie c iaie?aei?noth ii?aeiaiiai aaiaco aeyaeaia ii?oieia?/ia aaoa?iaaii?noue iioeeo?a, a oaeiae aenieee a?aenioie iioeeo?a c iciaeaie aeaaaia?aoe?? yaea?iiai iaoa??aeo (67,4%). Ii??aiyeueia ioe?iea aeei?enoaiiy ai?iiiaeueieo ? iaai?iiiaeueieo iaoiae?a ?iaeoeoe?? iaoeyoe?? iieacaea iiceoeaiee aieea AEIE ia ai?iiiaeueiee aiiainoac ae?iee. Aeei?enoaiiy AEIE cia/ii ciaioo? aeaaaia?aoeai? ci?ie yaea?iiai iaoa??aeo iioeeoo (iaeaea a 2 ?ace). 10. ?acoeueoaoe iaoaiaoe/iiai aiae?co iieaciee?a ianoaaeaiiy iaie?aeieo ae?iie aaeaeaaoi? ee?i?/i?e ea?oei? aeine?aeaeaiiai yaeua ? na?ae/aoue i?i iiaeeeaino? aeei?enoaiiy iine?aeiaii? noaoenoe/ii? i?ioeaaeo?e Aaeueaea aeey iiaoaeiae aeai?eoio i?iaiicoaaiiy eiia??iino? ianoaiiy aaa?oiino? ye aei, oae ? i?ney e?eoaaiiy ae?iie c iaie?aei?noth ii?aeiaiiai aaiaco. I?iaiinoe/ia ??oaiiy i?i canooieaiiy aaa?oiino? ia i?aenoaa? aeaiiai ianoaaeaiiy iaie?aeii? ia?e iiaeia cae?enieoe ca aeiiiiiaith ia iaioa o?ueio iieaciee?a, ui i?aeoaa?aeaeo? ee?i?/io nooue ?ai?iaeoeoeaii? nenoaie, ye aaaaoieiiiiiaioii?, ?acoeueoao ooieoe?iioaaiiy yei? iia'ycaiee c aaaaoueia oaeoi?aie. 11. ?acoeueoaoe aea/aiiy oeaio?aeueieo ? ia?eoa??eieo eaiie ii?ooaiiy ?ai?iaeoeoeaii? nenoaie o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? aoee acyo? ca iniiao iaa?oiooaaiiy ? ?ic?iaee aeeoa?aioe?eiaaii? oa?ai?? ??cieo oi?i iaie?aeiino?, ui i?aeaeueei aoaeoeai?noue ?? ia 25,0% ? nei?ioeei oa?i?i e?eoaaiiy ia 2-3 ?iee. I?AEOE*I? ?AEIIAIAeAOe?? 1. A i?ioean? i?aai?caoe?? ianoaaeaiiy ? e?eoaaiiy ae?iie c ii?aeiaieieie oi?iaie iaie?aeiino?, ii/eiath/e c ae?ii/i? eiinoeueoaoe?? ? cae?i/oth/e niaoe?ae?ciaaieie noaoe?iia?aie iaiao?aeii i?iaiaeeoe iiaoaiia ee?i?ei-ia?aee?i?/ia ianoaaeaiiy c iaoith aecia/aiiy iniiaii? ? ae?oai?yaeii? i?e/eie iaie?aeiino?, aeeaeie iioeiaeaeaiiy i?aai?a ? nenoai, a oaeiae nai?/aniiai i?iaaaeaiiy nenoaie i?io?eaeoe/ieo ? e?eoaaeueieo caoiae?a, ui cieaeothoue aai onoaathoue i?e/eie, ye? i?ecaiaeyoue aei iaie?aeiino?. 2. Aeey ?iaioe eiinoeueoaoe?e "N?i'y ? oetha" oa niaoe?ae?ciaaieo noaoe?iia?ao ia no/aniiio ??ai? ?aeiiaiaeo?oueny aeei?enoaiiy nenoaie aaoiiaoeciaaiiai ee?i?ei-ia?aee?i?/iiai oanooaaiiy, ai?iaaaeaeaiiy aeai?eoio i?iaiicoaaiiy aoaeoeaiino? e?eoaaiiy iaie?aeiino?. 3. C iaoith i?io?eaeoeee iaie?aeiino? o ae?iie ?ai?iaeoeoeaiiai a?eo c caiaeueieie i?ioeanaie aai?oae?e a ii?aeiaii? c o?a?ii?iiith iaoee, neiae?iiii iie?e?noicieo y?/iee?a, aai?oaeueiei aiaeiiao??icii iaia'yceiaei ? aeeth/aiiy a eiiieaenio i?ioecaiaeueio oa?ai?th aioeieneaeaio?a, aioo??oiueiaaiiiai eaca?iiai ii?ii?iaiiy e?ia? oa niaoeeo?/iiai e?eoaaiiy a caeaaeiino? a?ae aeaeo iaoieia??. A e?ioe? e?eoaaiiy iaiao?aeii i?iaanoe ianoaaeaiiy i?io?aeiino? iaoeiaeo o?oa ? aecia/eoe ooieoe?iiaeueiee noai y?/iee?a. 4. A niaoe?ae?ciaaieo noaoe?iia?ao c iaoith aecia/aiiy aiaoii?/iiai ? ooieoe?iiaeueiiai noaio iaoeiaeo o?oa ? iaoee ?aeiiaiaeo?oueny i?iaaaeaiiy noao?aeoe?eii? a?aeaiiao?inaeuei?iaia?ao??, a i?e aai?oaeueiiio aiaeiiao??ic? oa o?a?ii?ii? iaoee - noao?aeoe?eii? aia?ia?ao??. 5. I?ae /an ioe?ithaaiiy noaio i?aai?a i?oaiae o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? ?aeiiaiaeo?oueny aeeth/eoe aea/aiiy aia?aaoe/iiai iioaioe?aeo aiaeiiao??th oeyoii aecia/aiiy aeoeaiino? oa?iaio?a aeeoaeueiiai eaioethaa, niaeo?o iaeo?aeueieo e?i?ae?a oa oinoie?i?ae?a ? noaio i?i- oa aioeieneaeaioii? nenoaie, i?e yeeo ne?ae a?aoiaoaaoe, ui iayai?noue a?iiene/ieo ci?i a aiaeiiao??? oa aeoeaaoe?y i?ioean?a ia?aeeniiai ieeneaiiy e?i?ae?a ia oii? ?icaaeainiaaii? ?aaoeyoe?? oa i?eai?/aiiy nenoaie aioeieneaeaioiiai caoenoo i?ecaiaeyoue aei ii?ooaiiy i?aeaoe?? caie?aeiaii? yeoeaee?oeie. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. I?ioeeaeoeea e ea/aiea niaa/iiai i?ioeanna i?aaiia iaeiai oaca i?e oe?o?ae/aneie ?aaaeeeoaoeee aeaiuei n aanieiaeeai // Aeoo. e aeiae.- 1985. - N 3. - N. 30-32, (Ni?aaao. E.?.?aaithoa, ?.A.Aiae, E.?.Noaio?ei). 2. Ee?i?/ia ioe?iea oaieia?c?eiiai iaoiaeo aeine?aeaeaiiy a ae?aaiinoeoe? ae?ii/i? iaie?aeiino? //Iaae?ao??y, aeooa?noai ? a?iaeieia?y ?6, 1986. - N.38-39 (Ni?aaao. E.?. ?aaithoa, ?.A. Aiae, O.I. Ooeueaeaiei). 3. Ae?aaiinoe/ia cia/ou?noue aaa?iaeueii? ?aia?ao?? i?e ioe?ioe? aaiiaeeiai?ee aeiaeaoe?a iaoee o ae?iie c iaie?aei?noth caiaeueiiai aaiaco // Iaae?ao??y, aeooa?noai ? a?iaeieia?y. - 1991. - N 4. N. 40-43, (Ni?aaao. E.?.?aaithoa, I.A.Ei?/einueea). 4. Eiioiieiae/aneea eciaiaiey o aeaiuei n aanieiaeeai ainiaeeoaeueiiai aaiaca e eo ei??aeoeey // Aeoo. e aeiae. 1992, N 8-12. - N. 45-48, (Ni?aaao. E.?. ?aaithoa, ?.A. Aiae, A.I. *a?ieoia). 5. Iniaeeaino? niaeo?a e?i?ae?a o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? // Oe?a?inueeee ea?ae?ieia?/iee aeo?iae. 1997. - N 2. - Aei.??. - N. 50-52. (Ni?aaao. E.?.?aaithoa, A.E.O?uaiei, N.E.No?eaeae). 6. A?aeaiiao?inaeuei?iaia?ao?y a eiiieaeni?e ae?aaiinoeoe? aioo??oiueiiaoeiai? iaoieia?? o ae?iie c iaaeiiooaaiiyi aaa?oiino? ? aoi?eiiith iaie?aei?noth // A ei. Iaaeiiooaaiiy aaa?oiino?, Ee?a, 1997. - N. 207-210. 7. No?oeoo?ii-ooieoe?iiaeuei? ci?ie aiaeiiao??th o ae?iie c iaaeiiooaaiiyi aaa?oiino? ? aoi?eiiith iaie?aei?noth // A ei. Iaaeiiooaaiiy aaa?oiino?. - Ee?a, 1997. - N. 210-212. 8. Noai ee?oeiiiai ?ioi?oaoo a aeei?i?oe? iaino?oaeueiiai oeeeeo o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? caeaaeii a?ae aaoi?ioiieo ?aaeoe?e aei iaa??aeueieo aioeaai?a // Iaae?ao??y, aeooa?noai ? a?iaeieia?y. - 1997. - N 2. - N. 80-82. 9. Aeina?ae aeei?enoaiiy " Ee?iio-Ae 100" o e?eoaaii? caiaeueieo caoai?thaaiue aai?oae?e ae?iie c iaie?aei?noth //E?ee . 1998. - N 1. - N. 10-12. (Ni?aaao. E.?.?aaithoa, I.?.Aae?n). 10. Iie?aiceie a oa?ai?? o?ii?/iiai naeuei?ia?oo o ae?iie c iaie?aei?noth//Oa?iaoeaaoe/iee aeo?iae.- 1998.- N 2.- N.89-91. (Ni?aaao. E.?.?aaithoa, I.?.Aae?n, A.E.Eiiae?aothe) 11. 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Oe?a?ie (Oace aeiiia?aeae), Iaeana, 1996.- N. 132. 28. Aeei?enoaiiy eaia?ineii?? a ae?aaiioeoe? oa e?eoaaii? ae?iie c ii?ooaiiyi ?ai?iaeoeoeaii? ooieoe?? // Oac. aeieeaae. Oe?aeinei-Aia?eeaineiai eiia?anna ii yiaeineiie/aneie oe?o?aee, Oe?aeia, Iaeanna, 6-7 ethiy 1997,- N. 108-109. (Ni?aaaoi?e: E.?. ?aaithoa, N.I.?aaithoa, I.?.Aae?n). 29. Ee?i?ei-ia?aee?i?/ia oa?aeoa?enoeea ae?iie c ii?aeiaieie oi?iaie iaie?aeiino? // A ei. Aeooaeuei? ieoaiiy o??o?a??, Ee?a-Oiaeueieoeueeee-A?iieoey, 1997. - N. 146-148. AIIOAOe?ss Ei?iaoeueea A.A. I?iaiicoaaiiy, i?io?eaeoeea ? iaa?oiooaaiiy iaoiaaiaoe/ii? oa?ai?? o ae?iie c ii?aeiaieie oi?iaie iaie?aeiino?. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe c? niaoe?aeueiino? 14.01.01 - Aeooa?noai ? a?iaeieia?y. - ?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? Aeaaeai?? iaaee/ieo iaoe Oe?a?ie, Ee?a, 1998 ?. I?iaaaeaii eiiieaenia ee?i?ei-ia?aee?i?/ia ianoaaeaiiy 500 ae?iie c ii?aeiaieie oi?iaie iaie?aeiino?, aecia/ai? iniiai? ? ae?oai?yaei? /eiieee, ui iaaaoeaii aieeaathoue ia ?ai?iaeoeoeaio ooieoe??. Anoaiiaeai? ia o?eueee aiaoii?/i? ? ooieoe?iiaeuei? ci?ie a i?aaiao ? nenoaiao, aea e aecia/aia eieae?caoe?y ? aeeaeia iioeiaeaeaiiy ?ai?iaeoeoeaii? nenoaie, ui aaaeeeai i?e iiaeaeueo?e ?ic?iaoe? oaeoeee ei?aeoe?? aeyaeaieo ci?i. Aecia/ai? iia? aeai? i?i i?noea i?iaeoeoe?? aioenia?iaeueii? ?cinainaa?e?caoe??, aaoi?ioii? ?aaeoe?? o iaie?aeieo ae?iie, anoaiiaeaia ?icaaeainiaai?noue iieaciee?a caaaeueiiai ?ioi?oaoo a a?ieia?/ieo ??aeeiao, iaiaeiicia/i? ci?ie a?iio?ca?ii-aiiaaeii? nenoaie, ye? caeaaeaoue a?ae aeaeo iaoieia??, aeeaeie iioeiaeaeaiiy, o?eaaeino? caoai?thaaiiy ? ii?aeiaiiy aeae?eueeio /eiiee?a. Aea/aiee aia?aaoe/iee iai?i a i?aaiao-i?oaiyo, oie?eoei- ? iiaaiac o ae?iie a niiioaiiiio ? noeioeueiaaiiio iaino?oaeueiiio oeeeeao. ?ic?iaeai? aeai?eoie i?iaiicoaaiiy aoaeoeaiino? e?eoaaiiy, aaeineiiaeaia ? iaoeiai iaa?oioiaaia eiioeaioe?y iiaoaiiiai, aeeoa?aoe?eiaaiiai, c o?aooaaiiyi ao?ieia?/ieo ? iaoiaaiaoe/ieo /eiiee?a i?aeoiaeo aei nenoaie caoiae?a ii i?io?eaeoeoe? ? e?eoaaiith ae?iie c iaie?aei?noth ii?aeiaiiai aaiaco, ui aeicaiey? cia/ii i?aeaeueoe a?aenioie iiceoeaieo ?acoeueoao?a. Eeth/ia? neiaa: ae?iee, iaie?aei?noue, iaoea, y?/ieee, iaoeia? o?oae, ae?aaiinoeea, i?iaiicoaaiiy, aeeoa?aioe?eiaaia e?eoaaiiy. AIIIOAOeEss Ei?iaoeeay A.A. I?iaiice?iaaiea, i?ioeeaeoeea e iainiiaaiea iaoiaaiaoe/aneie oa?aiee o aeaiuei n ni/aoaiiuie oi?iaie aanieiaeey. - ?oeiienue. Aeenna?oaoeey ia nineneaiea iao/iie noaiaie aeieoi?a iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.01. - Aeooa?noai e aeiaeieiaey. - Einoeooo iaaeeao?ee, aeooa?noaa e aeiaeieiaee Aeaaeaiee iaaeeoeeineeo iaoe Oe?aeiu, Eeaa, 1998 a. I?iaaaeaii eiiieaeniia eeeieei-ia?aeeeie/aneia ianeaaeiaaiea 500 aeaiuei n ni/aoaiiuie oi?iaie aanieiaeey e ii?aaeaeaiu iniiaiua e aoi?inoaiaiiua oaeoi?u, eioi?ua io?eoeaoaeueii aeeytho ia ?ai?iaeoeoeaioth ooieoeeth. Onoaiiaeaiu ia oieueei aiaoiie/aneea e ooieoeeiiaeueiua eciaiaiey i?aaiia e nenoai, ii e ii?aaeaeaia eieaeecaoeey e aeoaeia iia?aaeaeaiey ?ai?iaeoeoeaiie nenoaiu, /oi aaaeii i?e aeaeueiaeoae ?ac?aaioea oaeoeee ei??aeoeee auyaeaiiuo eciaiaiee. Ii?aaeaeaiu iiaua aeaiiua i?i ianoi i?iaeoeoeee aioenia?iaeueiie ecinaineaeeecaoeee, aooieioiiua ?aaeoeee o aanieiaeiuo aeaiuei, onoaiiaeaia ?anaaeeaine?iaaiiinoue iieacaoaeae iauaai eiioieoaoa a aeieiae/aneeo aeeaeeinoyo, iaiaeiicia/iua eciaiaiey aeiioeca?ii-aiiaaeiie nenoaiu, eioi?ay caaeneo io aeaea iaoieiaee, aeoaeiu iia?aaeaeaiey, aeeeoaeueiinoe caaieaaaiey e ni/aoaiey ianeieueeeo i?e/ei. Eco/ai yia?aaoe/aneee iaiai a i?aaiao-ieoaiyo, oieeeeoei- e iiaaiac o aeaiuei a niiioaiiii e noeioee?iaaiiii iaino?oaeueiii oeeeeao. ?ac?aaioaiu aeai?eoiu i?iaiice?iaaiey aoaeoeaiinoe ea/aiey, oniaa?oainoaiaaia e iao/ii iainiiaaia eiioeaioeey iiyoaiiiai , aeeooa?aioee?iaaiiiai, n o/aoii yoeieiae/aneeo e iaoiaaiaoe/aneeo oaeoi?ia iiaeoiaea e nenoaia ia?ii?eyoee ii i?ioeeaeoeea e ea/aieth aeaiuei n aanieiaeeai ni/aoaiiiai aaiaca, eioi?ua iicaieeee cia/eoaeueii oaaee/eoue i?ioeaio iieiaeeoaeueiuo ?acoeueoaoia. Eeth/aaua neiaa: aeaiueiu, aanieiaeea, iaoea, ye/ieee, iaoi/iua o?oau, aeeaaiinoeea, i?iaiice?iaaiea, aeeoa?aioee?iaaiiia ea/aiea. SUMMARY Kornatzkaja A.G. Forecasting, prophylaxis and substantiation of pathogeny therapy in women with combined forms of infertility. - Manuscript. The dissertation for competition of a scientific degree of the doctor of medical sciences on a speciality 14.01.01. - Obstetrics and Gynaecology. - Institute of Pediatrics, Obstetrics and Gynaecology. Academy of Medical Sciences of Ukraine, Kiev, 1998. Complex clinical and paraclinical examination was carried out in 500 women with combined forms of infertility. There were determinated basic and secondary factors which have negative influence on reproductive function. Anatomic and functional changes were established in organs and systems as well as localization and depth of damage of reproductive system. All these had great importance for the further development of tactics for correction of revealed changes. There were determinated the new data concerning locus of antispermal isosensibilization production, autoimmune reaction in infertile women as well as misbalance of general immunity parameters in biological liquids, different changes in system hypophysis-gonades, depending on kind of pathology, depth of damage, disease duration and combination of several factors. There was studied the energy metabolism in organs-targets, folliculogenesis and oogenesis in women spontaneous and stimulated menstrual cycles. There were elaborated the forecasting algorithms of treatment efficiency, advanced and scientifically substantiated the concept of step-by-step, differential, considerably to etiologic and pathogen factors, approach to systematic measure in prophylaxis and treatment of women with combined forms of infertility. All these permitted to increase significantly the percentage of favorable results. Key words: women, infertility, uterus, ovary, uterus tubes, diagnosis, forecasting, differential treatment.

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