1

I?i?noa?noai ioi?iie caei?ia’y Oe?a?ie

Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao

Ianoa?aiei Eaii?ae Aiaoie?eiae/

OAeE: 618.39-005.2-084

I?IO?EAEOEEA AAIINOAC?IEIA?*IEO II?OOAIUe I?E IA?AAe*ANIEO IIEIAAO,
ONEEAAeIAIEO IA?AAe*ANIEI ?IC?EAII IE?AeIEO IAIEIIIE

14.01.01 — aeooa?noai ? a?iaeieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a — 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Oe?a?inuee?e iaaee/i?e noiiaoieia?/i?e aeaaeai?? IIC
Oe?a?ie

Iaoeiaee ea??aiee:aeieoi? iaaee/ieo iaoe, i?ioani? A?iiiaa Aioii?ia
Iaea??aia, caa.eaoaae?e aeooa?noaa ? a?iaeieia?? Oe?a?inueei? iaaee/ii?
noiiaoieia?/ii? aeaaeai??

Io?oe?ei? iiiiaioe:aeieoi? iaaee/ieo iaoe, i?ioani? Ua?aaeiaa Aaeaioeia
Aanee?aia, caa?aeoaa/ eaoaae?e aeooa?noaa ? a?iaeieia?? ?1 Oa?e?anueeiai
?inoeoooo oaeineiiaeaiiy e?ea??a

aeieoi? iaaee/ieo iaoe Eeiei Ienaia Iao??aia, i?ioani? eaoaae?e
aeooa?noaa ? a?iaeieia?? ?1 Oa?e?anueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo

I?ia?aeia onoaiiaa:?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? AII
Oe?a?ie, a?aeae?eaiiy iaoieia?? aaa?oiino? oa iieia?a

Caoeno a?aeaoaeaoueny » 11 ” aa?aciy 1999 ?. i 13-30 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.600.01 i?e Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca aae?anith: 310022, i. Oa?e?a,
i?.Eai?ia 4

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ca aae?anith: 310022, i. Oa?e?a,
i?.Eai?ia 4

Aaoi?aoa?ao ?ic?neaiee “ 9 ” n?/iy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

e.i.i., aeioeaio
I.I.Oaiueei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. Na?aae ??cieo aeae?a aeooa?nueei? iaoieia??
aaii?aa?/i? oneeaaeiai-iy aanoaoe?eiiai i?ioeano caeiathoue iaeia c
aaaeo/eo i?noeue. Aeooaeuei?noue oe??? i?iaeaie iao-iiaeaia aaaiiei
aianeii ?? a no?oeoo?o iaoa?einueei? nia?oiino?.

Aeooa?nuee? e?iaioa/?, iia’ycai? c ii?ooaiiyi i?e?icn?aeaiiy e?ia?,
caeiathoue iaeia c ia?oeo i?noeue na?aae i?e/ei iaoa?einueei?
eaoaeueiino? a?eueoino? ?icaeiooeo e?a?i na?oo (I.A.?ai?ia, 1986;
A.E.Eaiei ? ni?aaao., 1990; O.?.A?eie?eieoeueea, 1991; A.Ae.Iaeaoea??y ?
ni?aaao., 1993; A.?.A?euaiei ? ni?aaao., 1997; J.H.Rand et al., 1985).

Iaaiee i?ia?an a aeai?e i?iaeai? aeinyaiooi caaaeyee ?ic?iaoe? ?
ai?iaaaeaeaiith a aeo-oa?nueeo i?aeoeeo iiiyooy “a?oie ?eceeo” ii
?icaeoeo e?iaioa/?, c’ynoaaiith iiaeo eaioeth-a?a iaoiaaiaco, iaoiae?a
ae?aaiinoeee oa i?io?eaeoeee neiae?iio aeenai?iiaaiiai
aioo??oiuei-noaeeiiiai cn?aeaiiy (A.Ae.Iaeaoea??y ? ni?aaao., 1981,
1991; A.I.I?uaiei, 1988; A.N.A?oaii-iia ? ni?aaao., 1993; A.A.Sharp et
al., 1983; R.O.Norman et al., 1985).

Oiciieiai/ii ciiie iiae /an aaaioiinoi aiaeiinyoueny aei oeiiaeo i?iyaia
neiae?iio caaaeue-ii? oee?eoeyoi?ii? aaeaioaoei? aei aaaioiinoi i
iieiaia (A.Ae.Iaeaoea??y i niiaaao.,1985; A.I.Na-aaeue?aa i niiaaao.,
1991; S.Bondurant et al., 1984). Aaaeeeaith eaieith iaoiaaiaco
/eneaiieo oneeaaeiaiue a aeooa?nueeie i?aeoeoei ? ii?ooaiiy a nenoaii
aaiinoaco ia c?acie neiae?iio AeAC (I.A.??i?ia i niiaaao.,1985;
A.Ae.Iaeaoea??y i niiaaao., 1986; A.I.Na?ia i niiaaao.,1987;
A.N.A?oaiiiia i niiaaao.,1993; A.E.Aeeaiacyi,1995; L.M.Talbert et
al., 1979; R.D’Anna et al., 1987; Z.Marozio et al., 1987).

Caeeoa?oueny aenieei aiaenioie e?iaioa/ i?e ia?aae/anieo iieiaao (II),
yeee eiee-aa?oueny aiae 2,5% aei 20,2% (A.I.Aieoa?a i niiaaao., 1980;
A.I.Neaeaeueieeiaa, 1986; E.A.Oeii-oaiei i niiaaao., 1987; I.A.??i?ia,
1988; W.Hathway et al., 1978; I.M.Foiidart et al., 1984). A naith /a?ao,
ia?aae/anii iieiae c ia?aae/aniei ?ic?eaii ieiaeieo iaieiiie (I?II) a
38% oneeaaeiththoueny iaoieiai/ieie e?iaioa/aie (E.A.Oeiioaiei i
niiaaao., 1984; A.O.Ee?/oe i niiaaao., 1991; I.O.Ieoaeeaiei, 1994;
I.I.A?eai?aiei i niiaaao., 1995; S.Ferrari et al., 1981, T.C.Inglish et
al., 1982).

Iniaeeai aaeeei? oaaae caneoaiao? canoinoaaiiy iaiaaeeeaiaioicieo
iaoiae?a eieoaai-iy a aeooa?nueeie i?aeoeoei, ye? ia iathoue iiai/iiai
aieeao ia i?aaiici iaoa?i i ieiaea (E.Ae.Caieaiiaa, 1989; A.E.Nieiaeiaa
i niiaaao., 1990; I.N.Cieiooo?i i niiaaao., 1992; E.A.Ei-eiiae/oe i
niiaaao., 1993; I.Lackinger, 1989; B.A.Blanchard et al., 1993). Iaeiei c
oaeeo iaoiaeia ? aeei?enoaiiy iecueeiaia?aaoe/iiai eaca?iiai
aei?iiiithaaiiy, yea ia aieeaa? iaaaoeaii ia ieiae, c oniioii
canoiniao?oueny i?e eieoaaiii aanoicia, aeno?aaai?oaeueii? iaoieiai?
aaaio-ieo oa oneeaaeiaiiyo iiney?iaeiaiai ia?iiaeo. A e?oa?aoo?? ia
inio? ?aeeii? aeoiee i?i aieea iecueeiiioaineaiiai eaca?iiai i?iiaiy ia
nenoaio aaiinoaco. O ca’yceo c oeei, aea/aiiy noaio nenoaie aaiinoaco
i?e II i II c I?II oa ?ic?iaea ?aoeiiiaeueii? iaoiaeeee eaca?ii?
oioiaiiaei? ia nenoaio cniaeaiiy e?iai ? aeooaeueieie.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoeiy ?
o?aa-iaioii eiiieaenii? oaie «Aieea ciii aiiainoaco aioo?ioiueiai
na?aaeiaeua i?aaiicio aa-aioieo i?e aeooa?nueeie oa aeno?aaaiioaeueiie
iaoieiai? i iaoiaeia ?iaei?ic?ioaiiy ia ia?aaia aaaioiinoi, iieiaia,
iineyiieiaiaiai ia?iiaeo, noai ieiaea i iiaiia?iaeaeaiiai oa ei?aeoeiy
ae-yaeaieo ii?ooaiue», yea aeeiio?oueny ia eaoaae?i aeooa?noaa i
aiiaeieiai? Oe?aiinueei? iaaee/-ii? noiiaoieiai/ii? aeaaeaii? (iiia?
aea?aeaaii? ?a?no?aoei? 019600451).

Iaoa aeineiaeaeaiiy. C’ynoaaiiy iniaeeainoae iaoiaaiaco
aaiinoac?ieia?/ieo oneeaae-iaiue ia?aae/anieo iieia?a oa ?ic?iaea
iaiaaeeeaiaioicieo iaoiae?a aieeao ia aaiinoac i?e II.

Caaea/i aeineiaeaeaiiy:

1. Aea/eoe iniaeeainoi aiaiiaco, ia?aaiao aaaioiinoi o aeiiie c
ia?aae/anieie iieiaa-ie, a oiio /enei c ia?aae/anieie iieiaaie oa
ia?aae/aniei ?ic?eaii ieiaeieo iaieiiie, i ae-cia/eoe oaeoi?e, ui
ni?eythoue io aeieeiaiith.

2. C’ynoaaoe iniaeeainoi nenoaie aaiinoaco i?e caa?ici ia?aae/anieo
iieiaia oa ia?aae-/anieo iieiaao c ia?aae/aniei ?ic?eaii ieiaeieo
iaieiiie.

3. Aecia/eoe ciiie aa?aaaoiiai noaio e?iai i?e canoinoaaiii
o?aaeeoeieiii oa?iaeioa-?aii? caa?ice ia?aae/anieo iieiaia oa i?e II.

4. ?ic?iaeoe aeinooiio oa aacia/io iaoiaeeeo iecueeiiioaineaiiai
eaca?iiai aieeao ia aaiinoac i?e II oa I?II c iaoith i?ioieaeoeee
aioo?ioiueinoaeeiiiai iie?icniaeaiiy e?iai.

5. Aea/eoe aieea ciaiioiueiai iecueeiiioaineaiiai eaca?iiai
ii?iiiithaaiiy e?iai ia aa?aaaoiee noai e?ia? oa aioo?ioiueioo?iaiee
ie?ae i?e caa?ici ia?aae/anieo iieiaia ? ia?aae-/anieo iieiaao c
ia?aae/aniei ?ic?eaii ieiaeieo iaieiiie.

6. Aecia/eoe noai oiiono iaoee i eiai ciiie i?e i?iaaaeaiii
iecueeiiioaineaiiai ea-ca?iiai aieeao a iaeanoi neiiea?ioeaeii? ciie.

Iaoeiaa iiaecia. Ia no/aniiio ?iaii iiaeeaeai? oyaeaiiy i?i iniaeeainoi
aaiinoa-co i?e caa?ic? ia?aae/anieo iieiaia i i?e ia?aae/anieo iieiaao c
ia?aae/aniei ?ic?eaii iei-aeiaeo iaieiiie. Aia?oa aeyaeai?
aaiinoac?ieia?/i? ia?ea?e aeiee?i?/ieo iciae II.

Iaoeiai iaa?oioiaaia iaiaoiaeiinoue i?iaaaeaiiy ciaiioiueiai
iecueeiiioaineaiiai ea-ca?iiai ii?ii?ithaaiiy i?e aeieeiii/ieo i?iyaao
caa?ice ia?aae/anieo iieiaia i ia?aae/anieo iieiaao c I?II, yea
iiaeaeuo? eiiiainaoi?ii oa aaeaioaoeieii iiaeeeainoi nenoaie aaiinoaco.

I?aeoe/ia cia/aiiy. Aeyaeai? ii?ooaiiy aaiinoaco i?e ia?aae/anieo
iieiaao aei-caieeee noi?ioaaoe na?aae aaa?oieo ae?iie a?oio ?eceeo, yea
iio?aao? ei?eaoth/i? aaiinoac oa?ai??.

Cai?iiiiiaaii aeey caeeaae?a i?aeoe/ii? iaaeeoeeie i?ei?iyoe a eiiieaen?
c o?aaeeoe?e-ieie iaoiaeaie ciai?oi? iecueei?ioaineaia eaca?ia
ii?ii?ithaaiiy e?ia? a neiiea?ioeaei?e cii? c iaoith i?io?eaeoeee
ia?aae/anieo iieia?a, ia?aae/aniiai ?ic?eao ie?aeiiai i?oo?a, ciaioaiiy
/anoioe iaoieia?/ii? e?iaiao?aoe a iieiaao i?e oeeo oneeaaeiaiiyo
aanoaoe?eiiai i?ioeano.

?ic?iaeaii aeinooiiee aeey oe?iei? i?aeoeee niinia i?ioieaeoeee
eiaaoeiiaoe/ieo e?iaioa/ i?e ia?aae/anieo iieiaao (iaoaio Oe?a?ie ia
aeiaoiae ?21344A), yeee ia? ?yae ia?aaaa: a?aenooi?noue i?ioeiieacaiue,
eaae?noue aeei?enoaiiy, a?aeiinia aeaoaaecia, a?aenooi?noue iaaaoeaii?
iaaeeeaiaioicii? ae?? ia aioo??oiueioo?iaiee ie?ae ? aaa?oio,
ia?iaaceai?noue, ii-aea?eia ae?y (ye ia no?oi e?ia?, ui ?ooa?oueny ii
niii?e a?oa???, oae ? ia ?aoeaeniaaiio neiiea-?ioeaeio ciio) eaca?iiai
i?iiaiy, a?aenooi?noue iaiao?aeiino? eiaaoeieia?/iiai eiio?ieth.

Oei ?aeiiaiaeaoeii ai?iaaaeaeaii a ?iaioo Iieoaanueeiai iinueeiai
iieiaiaiai aoaeeieo oa iieiaiaeo aiaeaeieaiue Eoaainueei?,
Oi?ieuenueei?, Ciiueeianueei? Oe?E Iieoaanueei? iaeanoi.

Iniaenoee aianie caeiaoaa/a. Aeena?oaioii naiino?eii iaa?oioiaai? iaoa
oa caaaeai-iy aeine?aeaeaiiy, aea?ai? aaeaeaaoi? iaoiaee/i? caoiaee,
i?iaaaeai? iaoeia? aeine?aeaeaiiy, ianoa-aeai? aaa?oi? ca aeiiiiiaith
no/anieo iaoiae?a ae?aaiinoeee, i?iaaaeai? aaiinoac?ieia?/i?
aei-ne?aeaeaiiy o ae?iie c ia?aae/anieie iieiaaie, ?ic?iaeaia a?oia
?eceeo oa iaoeiai iaa?oioi-aaii iaiaaeeeaiaioiciee iaoiae i?io?eaeoeee
aiianoac?ieia?/ieo ii?ooaiue. Aaoi? i?eeiaa iniaenoo o/anoue o
ai?iaaaeaeaii? ?acoeueoao?a aeine?aeaeaiiy a i?aeoe/io iaaeeoeeio.

Ai?iaaoeiy ?acoeueoaoia aeena?oaoeii. Iaoa?iaee i iniiaii iieiaeaiiy
aeena?oaoei? aoee i?aaenoaaeaii ia O c’?caei aeooa?ia-aiiaeieiaia
Oe?a?ie (i.Iaeana, 1996 ?ie), iiaeia?iaeiie eii-oa?aioei? «Oic?ieiaiy i
iaoieiaiy iioiioaoo, aaiinoaco, ia?aeeniiai ieeneaiiy eiiiaeia»
(i.Iieoaaa, 1997 ?ie), iaoeiai-i?aeoe/ieo eiioa?aioeiyo Iieoaanueeiai
iinueeiai eeiii/iiai iieiaiaiai aoaeeieo (i.Iieoaaa, 1997 ?ie). ?iaioa
caneooaia ia Iaoeiaie ?aaei ii ai?iaaoei? aeena?oaoeie Oe?aiinueei?
iaaee/ii? noiiaoieiai/ii? aeaaeaii?.

Ioaeieaoei?. Ca iaoa?iaeaie aeineiaeaeaiue iioaeieiaaii 7 ae?oeiaaieo
?iaio, c ieo 4 aac niiaaaoi?ia. 5 i?aoeue iioaeieiaaii o aeaeyaei oac; 2
noaooi — o aeo?iaei «Aanoiee i?iaeai aei-eiaee e iaaeeoeeiu». Io?eiaiee
iaoaio Oe?a?ie ia aeiaoiae ?21344A aiae 02.12.97 ?ieo «Nii-nia
i?ioieaeoeee eiaaoeiiaoe/ieo e?iaioa/ i?e ia?aae/anieo iieiaao».

Ianya oa no?oeoo?a aeena?oaoeii?. Aeena?oaoeiy neeaaea?oueny c anooio,
iaeyaeo eioa?aoo?e, 2 ?icaeieia, a yeeo iienaii iaoa?iaee oa iaoiaee
aeineiaeaeaiiy i caaaeueia eeiii/ia oa?aeoa?en-oeea ianoaaeaieo aeiiie,
2 ?icaeieia aeanieo aeineiaeaeaiue, caeeth/aiiy, aeniiaeia, i?aeoe/ieo
?aeiiaiaeaoeie i nieneo aeei?enoaii? eioa?aoo?e, yeee neeaaeaaoueny c
207 aeaea?ae (a oiio /en-ei 69 aaoi?ia aeaeueiueiai ca?oaiaeaey). Ia’?i
aeena?oaoei? — 121 coi?iiea oaenoo, a oiio /enei 23 oaaeeoei, 9
iaethieia.

INIIAIEE CIINO ?IAIOE

Iaoa?iaee i iaoiaee aeineiaeaeaiiy. ?iaioa aeeiiaia ia aaci eaoaae?e
aeooa?noaa i ai-iaeieia?, Oeaio?aeueii? iaoeiai-aeineiaeii? eaai?aoi?i?
Oe?a?inueei? iaaee/ii? noiiaoieiai/ii? aeaaeaii?, oa Iieoaanueeiai
iinueeiai eeiii/iiai iieiaiaiai aoaeeieo.

Aeey ae?ioaiiy iinoaaeaieo caaaeaiue aoei i?iaiaeiciaaii 250 inoi?ie
iieiaia (a?oia-iee iaoa?iae), aeineiaeaeaii ia?aaia aaaioiinoi i iieiaia
o 193 aeiiie, yeei aoee i?iaaaeai? oeueo?acaoeia?, ea?ae?ioieia?ao?/i?
oa aaiinoac?ieia?/i? aeine?aeaeaiiy. C ieo: 61 ae?iea c I?II a oa?i?i?
aaa?oiino? 29-36 oeaei?a — iniiaia a?oia (IA), 31-?e c ieo i?iaiaeeeanue
eiiieaenia oa?ai?y, yea aeeth/aea ii?yae c aeei?enoaiiyi
aioeaaeoa??aeueieo i?aia?ao?a, niaciie?oee?a, i?aia?ao?a iie?iooth/eo
iaoeiai-ieaoeaioa?iee e?iaiia?a, cania?a i?io?eaeoeee NAe? iei-aea,
ciai?oi? iecueei?ioaineaia eaca?ia ii?ii?ithaaiiy e?ia? (CIEIE) — ?
iniiaia a?oia (?-IA). 30 — c ia?aae/aniei aeeeooyi iaaeieiie?aeii? aiaee
a eiiieaeni?e oa?ai?? io?eioaaee ani???i — ? a?oia ii??aiyiiy (?-IA); 40
?iae?eue a ia?oiio ia??iae? iaoneeaaeiaieo nai?/anieo iieia?a ooai?eee
eiio?ieueio a?oio (EA); 32 — a ? ia??iae? ia?aae/anieo iieia?a c oe?eei
ie?ae-iei i?oo?ii — a?oia ii??aiyiiy (AI); 30 aaa?oieo c aeiee?i?/ieie
iciaeaie caa?ice II, 15 c yeeo io?eioaaee o?aaeeoe?eio caa??aath/o
aaa?oi?noue oa?ai?th c canoinoaaiiyi ani???ia — ?? a?oia ii??aiyiiy
(??-AI) oa 15 — a eiiieaen? caa??aath/i? oa?ai?? i?iaiaeeeinue CIEIE —
?? iniiaia a?oia (??-IA).

30 caei?iaeo aaa?oieo ae?iie a 29-36 oeaei?a ooai?eee ? eiio?ieueio
a?oio (?-EA). I?i-aiae?ciaai? iniaeeaino? ?icaeoeo 61 iiaiia?iaeaeaiiai.
Ii?yae ic caaaeueiieeiii/iei ianoa-aeaiiyi aaaioieo i ii?iaeieue o
ianoaaeaieo aeiiie i?iaiaeeeenue aaiinoaciieiai/ii aeineiaeaeaiiy ye
iiae /an aaaioiinoi, oae i iiney I?II oa a I ia?iiaei ?iaeia. Aea/aee
o?iiaioeeoa?io, i?i-eiaaoeyioio oa oia?iiieioe/io eaiee aaiinoaco ca
iaoiaeeeaie I.A.Eioiaueeiai?, C.Ae.Oa-aei?iai? (1966); A.A.Aiae?i?iei,
A.I.Aaeoaee, C.N.Aa?eaaaia, A.E.Aieueaeaa?aa (1980); I.A.Ea?a-aaniai?,
E.A.Eaoiai? (1981).

Ea?aeiioieia?aoiy i?iaiaeeeanue oaoaeueiei aiiiiiioi?ii AIO 9141. Noai
aioo?ioiuei-oo?iaiiai ieiaea ioeiithaaee oeyoii aiae?co EOA ca oeaeith
W.Fisher oa niiaaaoi?ia (1976). Oeueo?acaoeiaa aeineiaeaeaiy
i?iaiaeeeinue aia?aoii «Combison 320-5 KRETZ TECHNIK» (Aano?iy).

Aeey i?ioieaeoeee oa ei?aeoei? aaiinoaciieiai/ieo ii?ooaiue i?e caa?ici
II oa II c I?II aeei?enoiaoaaany ?ic?iaeaiee ia iiaenoaai iaoiaeeee
?.A.E?aniiiieuenueeiai (1988) “Niinia i?ioieaeoeee aaiinoaciieiai/ieo
ii?ooaiue i?e II, oneeaaeiaieo I?II” (iaoaio Oe?a?ie ia aeiaoiae
?21344A) oeyoii ciaiioiueiai iecueeiiioaineaiiai eaca?iiai
ii?iii-ithaaiiy e?iai a neiiea?ioeaeiie ciii. Aeei?enoiaoaaee
aaeie-iaiiiaee eaca?iee aia?ao «AOIEE», noai?aiee ia aaci EAI-3. ?aaeei
?iaioe: aeiaaeeia oaeei 0,63 iei, ?aaeei aei?i-iiithaaiiy —
aacia?a?aiee, iiooaeiinoue aei?iiiithaaiiy ia ae-oiaei 10 iAo, /an
aeniiceoeii — 600n. I?iaaaeaii 416 naainia.

Io?eiaii ?acoeueoaoe noaoenoe/ii ia?iaeaii iaoiaeaie aa?iaoeieii?
noaoenoeee c aeei-?enoaiiyi e?eoa?ith No’thaeaioa — Oioa?a (A.I.Cthcii,
1995).

?ACOEUeOAOE AeINEIAeAEAIUe OA ?O IAAIAI?AIIss

Ia iiaenoaai aea/aiiy a?o?aiiai iaoa?iaeo aiaecia/aii, ui aeinoiai?ii
/anoioa I?II i?e iaaeiiioaiie aaaioiinoi ia?aaeoaaee aiaiiy (46,0±7,0%),
caa?ica ia?a?eaaiiy aaaioiinoi (46,0±7,0%), A?AI (16,0±5,2%),
iiaeiiao?eo (10,0±4,6%), eieueiio (30,0±6,5%), aaaaoiaiaeaey
(16,0±5,2%). Noai aeioae, ui ia?iaeeeenue i?e I?II a 29-36 oeaeiia
aaaioiinoi, aoa ioeiiaiee ca oeaeith Aiaa? ia 2,4 aaea ( ?<0,05) ieae/a, iiae i?e NI i i?aeoe/ii ia aiae?iciyany aiae noaio aeioae, ui ia?iaeeeeny aiae II c nai?/aniei aeeeooyi aiaee (NAA). Caaaeueia e?iaiao?aoa a II c I?II a 1,3 ?ace ia?aaeuoaaea oaeo i?e NI (?<0,02) i a 1,2 ?ace (?<0,05) - i?e II c NAA. Aiiioiii/ia e?iaioa/a i?e II c I?II aiaeii/aeanue o 14,0±3,5% aeiiie, ui a 4,7 ?acia aieueoa (?<0,01), iiae o aeiiie ic nai?/anieie iieiaaie, a i?e II c NAA - o 10,0±3,0%, ui a 3,3 ?ace aieueoa (?<0,05), iiae a eiio?ieueiie a?oii. Aea/aiiy o?iiaioeeoa?ii? eaiee aaiinoaco o ianoaaeaieo aeiiie iieacaei, ui eieue-einoue o?iiaioeeoia o ieo ciaoiaeeeanue a iaaeao na?aaeiueiiiioeyoeieieo iieacieeia. Oae, a IA oeae iieaciee noaiiaea 242,2±8,7·109/e, ui ia 10,3% iaioa, i?ae a EA (270,1±9,3·109/e; p<0.05) ? ia 18,8% iaioa, i?ae a AI (298,2±8,4·109/e; p<0.001). Iiaeeeai i?eionoeoe, ui o?iiaioeeoe aeei?enoiaothoueny ia aioo?ioiueinoaeeiia o?iiaiooai?aiiy, yea aeieea? i?e II c I?II. Oea iiaeoaa?aeaeo?oueny iieacieeaie aa?aaaoia?aie. Oae, a IA aiaeii/a?oueny nei?i/aiiy /ano aa?aaaoeii o?iiaioeeoia ia 16,1% (c 11,8±0,22oa aei 9,9±0,2oa; ?<0,001) oa iiaeaeuaiiy eooa aa?aaaoei? ia 8,2% (c 49,1±1,09a?aae aei 62,3±1,04a?aae; ?<0,01) a ii?iaiyiii c eiio?ieai. Ioaea, i?e II c I?II ia? iinoea iiaeaeuaiiy ooieoeiiiaeueii? aeoeaiinoi o?iiaioeeoia oa aeoeaaoeiy noaeeiii-o?iiaioeeoa?iii eaiee aaiinoaco. I?e aea/aiii eiaaoeyioiii eaiee nenoaie aaiinoaco o aeiiie c II oa I?II aiaeii/a-einue nei?i/aiiy i?io?iia?iiaiai /ano aei 15,3±0,58n i?ioe 18,6±1,04n a AI (p<0,01) i o?ii-a?iiaiai - aei 18,6±0,63n i?ioe 23,4±0,41n a AI (p<0,001), ui naiae/eoue i?i aeoeaaoeith i?ioea-nia cai?oaiiy e?iai ca ciaiioiii iaoaiiciii, iiaeeeai iia'ycaio c iiyaith a noaeeiiiio ?onei oeaieiiiai o?iiaiieanoeio aianeiaeie ia?aae/aniiai aeeeooy iaaeieiieiaeii? aiaee. A IA ia 12% caieueooaaeanue aeoeaiinoue aieiaiiai aioeeiaaoeyioa e?iai - AO III (23,4 ± 1,16n) a ii?ia-iyiii c EA (26,8±1,07n; ?<0,05), oa ia 22,8 % - (30,3±1,16; ?<0,01) a ii??aiyii? c AI. Oea eiin-oaoo? iayaiinoue eiiiainaoi?iiai iai?oaeaiiy ?aca?aieo iiaeeeainoae aioeeiaaoeyioii? ne-noaie aaiinoaco i?e I?II a III o?eiano?i aaaioiinoi. Eiioeaio?aoeiy oia?eiiaaio a AI ia-cia/ii cieaeoaaeanue, a a IA - aeaui iiaeaeuoaaeanue aiaeiinii iieacieea a EA, aea o anio aeiiie caeeoaeanue a iaaeao ii?ie. A IA aiaeii/aeinue ciaioaiiy /ano oia?iiieico aoaeiaoeiiia aei 169,9±5,8oa., ui naiae/eoue i?i aeoeaicaoeith oia?iiieioe/iii eaiee aaiinoaco. Io?eiaii ?a-coeueoaoe aeicaieeee ia?aaeaa/eoe iayaiinoue o aeiiie c II oa I?II I oace AeAC - neiae?iio - oace aiia?eiaaoeyoei?. I?e aea/aiii oanoia ia?aeiaaoeyoei? aeyaeaii ?icei iiceoeaii aoaiiei-aee oa -iaooieiaee, ui iiaeoaa?aeeei c?iaeaia ia?aaeaa/aiiy: oanoe aecia/aeenue oieueee o aeiiie c I?II i?e iaaeiiioaiie aaaioiinoi. I?iaaaeaiiyi oeueo?acaoeiai? ieaoeaioia?aoii o aeiiie c II oa I?II aeiaaiinoiaaia ia-?aae/ania noa?iiiy ieaoeaioe, oae aaea a 32 oeaeii aaaioiinoi aeyaeyeanue II nooiiiue ?? c?ieinoi. A 8,2±3,5% aeiaaeeia a oa?iiii aaaioiinoi 34-35 oeaeiia aiaeii/aeanue II - III nooiiiue c?ieinoi iea-oeaioe. O 28,1±7,9% aeiiie AI iiae /an aaaioiinoi aeiaaiinoiaaia iaaeeeoeiaa eieueeinoue iaaei-eiieiaeii? aiaee, a oie /an ye a IA oeae iieaciee neeaa 45,9±6,4%; (?<0,05). Oea aeicaieeei iai ?icoeiieoe ciiio eieueeinoi iaaeieiieiaeii? aiaee ye oaeoi? ?eceeo aeieeiaiiy I?II i?e ia-aeiiioaiie aaaioiinoi. Aeyaeaia caeaaeiinoue ia'?io e?iaiao?aoe a iieiaao aiae eieaeicaoei? ieaoeaioe a ii?iae-ieii iaoee. Oae, yeui i?e ?icoaooaaiii ieaoeaioe a ieaeiio aiaeaeieao iaoee na?aaeiy e?iai-ao?aoa noaiiaeea 406,0±62,9ie, oi i?e aeiiiie eieaeicaoeii - 272,2±22,1ie, ui ocaiaeaeo?oueny c aeaieie O.TH.Eyoianueei? (1995). Ea?aeiioieia?aoi/ia ioeiiea noaio aioo?ioiueioo?iaiiai ieiaeo ca oeaeith Fischer (1976) a a?oii aeiiie c II oa I?II noaiiaeea 6,8±0,27 aaea i?ioe 8,2±0,61 aaea (?<0, 05) a AI i 9,1±0,72 aaea (?<0,01) a a?oii aeiiie ic iaoneeaaeiaieie iieiaaie. Iieaciee oiiona iao-ee o aeiiie IA noaiiaea 6,2±0,3 oiia.iae. oa i?aeoe/ii ia aiae?iciyany aiae oaeiai a AI-7,1±0,1oiia.iae., aea aoa a 1,4 ?ace iaioee (?<0,05), iiae a eiio?ieueiie a?oii (8,7±0,3oiia.iae.). Ineieueee i?iaaaeaii eeiiiei-eaai?aoi?ii aeineiaeaeaiiy aeyaeee o aeiiie c II oa I?II ia?oo oaco o?iii/iiai AeAC-neiae?iio, a eiiieaen eieoaaeueieo caoiaeia i?e ia?aae/aniiio aeeeooi iaaeieiieiaeii? aiaee i iaaeiiioaiie aaaioiinoi ie aeeth/eee ?ic?iaeaiee niinia ei-?aeoe?? ii?ooaiue aaiinoaco oeyoii CIEIE. Ii?iaithaaee aeai? ianoaaeaiiy c iieacieeaie a?oie aeiiie, yeei a eiiieaenio oa?aiith aoa aeeth/aiee anii?ii (i?e II oa I?II - AI, i?e caa?ici II - II-AI). I?iaaaeaiiy eo?no CIEIE i?e I?II a 29-36 oeaeiia aaaioiinoi ni?eyei iiaeaeuaiith eieueeinoi o?iiaioeeoia ia 10,7%. ?iaaiue ?o aei ii/aoeo eieoaaiiy neeaa 242,2±8,7·109/e, a i?ney oa?ai?? 268,2±8,1·109/e, /iai ia aiaeii/aeinue o aeiiie, yei io?eioaaee anii?ii. Iieacieee aa?a-aaoia?aie oaae naiae/eee ia ei?enoue aieueo ae?aciii aei? CIEIE ia ooieoeiiiaeueio aeoeaiinoue o?iiaioeeoia, iiae canoinoaaiiy anii?iio (oaae.1). Oae, eoo aa?aaaoeii a I-AI cieceany ia 6,7% (c 62,3±1,04a?aae aei 58,1±1,11a?aae; ?<0,02), a a I-IA - ia 13,1% (c 62,3±1,04a?aae aei 54,2±1,1a?aae; p<0.001). Aiaeiai/ii ciiie aiaeii/aeenue i?e aea/aiii iieacieeia eiaaoeyoeieii-ai aaiinoaco. Iiney eaca?iii oioiaiioa?aii? iieaciee aeoeaiino? AO III cieceany ia 21% ? neeaa 28,4±0,53n a ii?iaiyiii c eiai cia/aiiyi aaciina?aaeiuei iiney I?II (?<0,001), a a I-AI oeae iieaciee aeinoiai?ii ia cieceany i noaiiaea 25,4±1,06n (oaae.2). Ii?iaiyiiy aeii ia aaiinoac anii?iio oa iao?aaeeoeieii? oa?aii? iieacaei, ui iiae aieeaii CIEIE iiaeaeuo?oueny /an oia?iiieico aoaeiaoeiiia ia 10,2% (c 169,9±5,8oa aei 189,2±4,48oa; ?< 0,01), a a I–AI, eiee i?ecia/aany ani???i - ia 7,8%(c 169,9± 5,8oa aei 184,3±4,37oa; ?<0,05). *anoioa aeyaeaiiy oa nooiiiue ae?aciinoi iieacieeia oanoia ia?aeiaaoeyoei? a I ia?iiaei ?iaeia a I-IA oa I-AI i?aeoe/-ii ia aiae?iciyeenue. Oaaeeoey 1.Iieacieee o?iiaioeeoa?ii? eaiee nenoaie aaiinoacoo ae?iie ianoaaeaiieo a?oiNaia/ani?1-e ia??iae II II c I?IIiieiaeC oe?eei ie?ae- Aei ii/aoeoO?aaeeoe?eia CanoinoaaiiyIieacieee(EA)Iei i?oo?ii e?eoaaiiye?eoaaiiy (ani?- IIEIEn=40 n=32 n=61??i) n=30 n=31I±mI±m?I±m?I±m?I±m?E?euee?noue?>0,25?>0,5O?iiaioeeo?a270,1±9,3298,2±
8,4 ?<0,05242,2±8,7?<0,05261,1±8,9?1<0,01268,2±8,1?1<0,02(10 9/e)?1<0,001?2>0,1?2<0,05?3>0,5*an?<0,001?<0,001Eaoaioii?25,4±0,5222,3±0 ,48?<0,00116,4±0,45?<0,00121,4±0,52?1>0,122,1±0,48?1>0,5Aa?aaaoe???1<0,0 01?2<0,001?2<0,001(n)?3>0,5*an?<0,001?<0,001Aa?aaaoe??11,8±0,2210,9±0,24 ?<0,019,9±0,2?<0,00110,5±0,21?1>0,110,8±0,14?1>0,5(oa)?1<0,001?2<0,05?2< 0,002?3>0,25Eoo?<0,001?<0,002Aa?aaaoe??49,1±1,0953,4±1,12?<0,0162,3±1,04 ?<0,00158,1±1,11?1<0,0154,2±1,14?1>0,5(a?aae)?1<0,001?2<0,02?2<0,001?3<0 ,02Aenioa?<0,001?<0,05Aa?aaaoe??3,2±0,112,8±0,09?<0,011,8±0,06?<0,0012,5 ±0,08?1<0,0022,9±0,09?1>0,25(ni)?1<0,001?2<0,001?2<0,001?3<0,001??cieoey ?>0,25Ci?ie?<0,001?<0,01?1<0,05Iioe/ii?28,8±0,5831,2±0,58?<0,00133,4±0,4 9?1<0,0130,9±0,52?1>0,529,6±0,39?2<0,001U?eueiino??2<0,001?3<0,05 ieacie DA I?ei?oea:? - aeinoia??i?noue ??cieoe? a ii??aiyii? c iieacieeaie o ae?iie c naia/anieie iieiaaie;?1 - aeinoia??i?noue ??cieoe? a ii??aiyii? c iieacieeaie o ae?iie a 1-io ia??iae? II n oe?eei ie?aeiei i?oo?ii;?2 – aenoia??i?noue ??cieoe? a ii??aiyii? c iieacieeaie o ae?iie aei ii/aoeo e?eoaaiiy;?3 – aeinoia??i?noue ??cieoe? a ii??aiyii? c iieacieeaie o ae?iie i?ney o?aaeeoe?eiiai e?eoaaiiy (ani???iii).Oaaeeoey 2Iieacieee i?ieiaaoeyioii? oa aioeeiaaoeyioii? eaiienenoaie aaiinoaco o ae?iie ianoaaeaiieo a?oiNaia/ani?1-e ia??iae II II c I?IIIieacieeiieiaec oe?eei ie?aei- Aei ii/aoeoO?aaeeoe?eia Canoinoaaiiyiei i?oo?ii e?eoaaiiye?eoaaiiy (ani?- IIEIEn=40 n=32 n=61??i) n=30 n=31I±mI±m?I±m?I±m?I±m?*an ?aeaeue-?>0,25?>0,5
Oeeo?eaoe??84,6±3,2781,2±3,29?>0,2578,4±3,46?>0,180,3±3,44?1>0,581,8±3,2
1?1>0,5 Ieaciu?1>0,5?2>0,5?2>0,25(n)?3>0,5I?io?iia?-?>0,1?>0,25iiaee
/an
18,6±1,0416,9±1,06?>0,2515,3±0,58?<0,0116,5±1,06?1>0,517,4±1,08?1>0,5
(n)?1>0,1?2>0,25?2<0,05?3>0,5O?iia?ii-?<0,001?<0,001 aee /an23,4±0,4121,1±0,56?<0,00118,6±0,63?<0,00119,6±0,49?1<0,0520,1±0,9?1>0
,1
(n)?1<0,01?2>0,1?2<0,05?3>0,25Aeoeai?noue?>0,25?>0,1aioeo?ii-26,8±1,0730
,3±1,16?<0,0523,4±1,16?<0,0525,4±1,06?1<0,00228,4±0,93?1>0,1a?ia
III?1<0,001 ?2>0,1?2<0,001(n)?3<0,02Eiioeaio?a-?<0,02?>0,5 oe?y
o?a??-4,2±0,173,2±0,21?<0,0013,8±0,21?>0,14,7±0,12?1<0,0014,3±0,12?1<0,0 01Iiaaia?1<0,05?2>0,5?2<0,05(a/e)?3<0,02O?a??ii-?<0,01?<0,05e?c ?oaei-203,4±4,78192,7±5,33?>0,1169,9±5,80?<0,001184,3±4,37?1>0,1189,2±4,
48?1>0,5Aoe?i?a?1<0,01?2<0,05?2<0,01(oa)?3>0,25 I?ei?oea:? —
aeinoia??i?noue ??cieoe? a ii??aiyii? c iieacieeaie o
ae?iie c naia/anieie iieiaaie;?1 — aeinoia??i?noue ??cieoe? a
ii??aiyii? c iieacieeaie o ae?iie a 1-io ia??iae? II n
oe?eei ie?aeiei i?oo?ii;?2 – aenoia??i?noue ??cieoe? a ii??aiyii? c
iieacieeaie o ae?iie aei ii/aoeo e?eoaaiiy;?3 – aeinoia??i?noue
??cieoe? a ii??aiyii? c iieacieeaie o ae?iie i?ney o?aaeeoe?eiiai
e?eoaaiiy (ani???iii).

Aiaeicoth/e iniaeeainoi ia?aaiao ?iaeia i iiney?iaeiaiai ia?iiaeo o
ianoaaeaieo aeiiie aiaeii/aii; ui a a?oi? ae?iie, yeeo e?eoaaee ca
aeiiiiiaith CIEIE ii??aiyii c a?oiith, yeeo e?eoaaee c aeei?enoaiiyi
ani???io, iaea i?noea iaioa e?euee?noue oneeaaeiaiue. Oae, /anoioa
neaaeino? ?iaeiai? ae?yeueiino? cieceeanue iaeaea a 2 ?ace (c 6,7% aei
3,2%; ?<0,05), a?iioii?/-ieo e?iaioa/ - a 3,1 ?ace (c 10,0% aei 3,2%; ?<0,05). E?iaiao?aoa, yea aei?iaithaaea 0,5% aiae iane oiea a I-IA cono?i/aeanue a 1,4 ?ace /anoi-oa (?<0,05), iiae a I-AI i iaaeeaeaeanue aei oaei? o aeiiie c oiciieiai/ieie iieiaaie. E?iai-ao?aoa aiae 401ie aei 500ie, ui aoea aieueo 0,5% iane oiea ?iaeieue, o ae?iie io?eioaaaoeo CIEIE, aiaeii/aeanue a 2,3 ?a-ce ?iaeoa (?<0,01), iiae a a?oii aeiiie, yeei i?ecia/aany anii?ii, i a 1,9 ?ace ?iaeoa (?<0,05), iiae a a?oii ii?iaiyiiy. Ineieueee ?ic?iaeaiee niinia ei?aeoei? aaiinoaciieiai/ieo ii?ooaiue i?e II c I?II ni?eya iie?auaiith iieacieeia aaiinoaco, ie canoiniao-aaee eaca?io oioiaiioa?aiith i?e caa?ici ia?a?eaaiiy aaaioiinoi. Aeiaaiic anoaiiaethaaee ca aeaieie OCAe, oiioniiao?ii, oi/a aoee a?aenooi? eeiii/i? i?iyae iaoieiai?. Oae, i?e caa?ici ia?aae/anieo iieiaia (CII) cieaeo-aaeanue eieueeinoue o?iiaioeeoia aei 243,2±8,8·109/e i?ioe 269,1±9,3·109/e (?<0,05) a I-EA. Iiney eo?no CIEIE eieueeinoue o?iiaioeeoia iiaeaeuoaaeanue ia 9,9%, i?aeoe/ii nyaath/e iieacieeia o caei?iaeo aaaioieo a III o?eiano?i. Niinoa?iaaeinue aeinoiai?ia ciaioaiiy /ano eaoaioiii aa?aaaoeii ia 14% (c 24,4± 0,53n aei 21,2±0,48n; ?<0,001), caieueoaiiy eooa aa?aaaoei? ia 10,8% (c 49,9± 1,09a?aae aei 55,3±1,14a?aae; ?<0,001), ?icieoei iioe/ii? uieueiinoi ieacie - ia 11,6% (c 26,7±0,56 aei 29,8±0,59; ?<0,001). Iiney i?iaaaeaiiai eieoaaiiy a II-IA oa II-AN iaeiaeiai cieaeoaaeanue aa?aaaoeieia aeoeaiinoue o?iiaioeeoia, ?? iieacieee iaaeeaeaeenue aei oa-eeo o caei?iaeo aaaioieo a III o?eiano?i. I?e CII ani iieacieee eiaaoeyoeieiii eaiee aaii-noaco a?ae??ciyeenue a?ae oaeeo a I-EA, ui naiae/eoue i?i aeoeaicaoeith o oeeo ae?iie nenoaie cai?oo-aaiiy e?iai i oia?iiieico. Canoinoaaiiy CIEIE ni?eyei iiaeiaaeaiith i?io?iiaiiiaiai /ano ia 20,3% (c 15,3±0,67n aei 18,4±0,86n; ?<0,01), o?iiaiiiaiai /ano - ia 10,9% (c 15,6±0,6n aei 17,3±0,4n; ?<0,02) a ii?iaiyiii c iieacieeaie aei eieoaaiiy i iaaeeaeaiith iieacieeia aei I-EA. A a?oii aeiiie, io?eioaaaoeo anii?ii, aiaeiI/aia oieueee oaiaeaioeiy aei ii?iaeicaoei? aaiinoaciia?ai ia?aaaaeii iieaciee?a noaeeiiio?iiaioeeoa?ii? eaiee, iacia/ii aieeaath/e ia noai eiaaoeyoeieii? i oia?iiieioe/ii? ?? eaiie. Aeyaeaiiy i?e CII iiceoeaieo ia?aeiaaoeyoeieieo oanoia iiaeoaa?aeaeo? noeeueiinoue anio eaiie nenoaie aaiinoaco aei aeoeaicaoeii. O 53,3±9,1% aeiiie c CII aeyaeyany b-iaooiei-aee oano, i?e oeueiio o 33,3±8,6% aii aoa neaaiiiceoeaiee. Iiney canoinoaaiiy anii?iio oeae oano aeyaeyany o 46,7±12,9% aeiiie, iiney CIEIE - o 20,0±10,3%, i?e/iio oieueee neaaiiice-oeaiee. sse aenieiiioi?iaoeaiee aoaiieiaee oano aeyaeyany o 20,0±7,3% aeiiie c CII i aoa iaaaoeaiei o anio aeiiie I-EA. Iiney i?iaaaeaiiai eieoaaiiy a II-AI eieueeinoue iiceoeaieo aoa-iieiaeo oanoia cieceeanue aei 20,0±10,3%, a a II-IA - aei 6,7±6,5%. O anio aeiiie oano aoa neaai-iiceoeaiei. Aea/aiiy iieacieeia oiioniiao??? i?e aeieeiii/ieo i?iyaao CII iieacaei, ui oiion iaoee o oeeo aeiiie noaiiaea 9,6±0,31 oi.iae. i a 1,5 ?acia (?<0,05) ia?aaeuoaaa oaei iieacieee o aeiiie ic oiciieiai/iei ia?aaiaii aaaioiinoi (6,3±0,2 oiia.iae.). Iiney i?iaaaeaiiy eo?no CIEIE aiaeii/aeinue cieaeaiiy oiiono iaoee aei 6,5±0,26 oi.iae. (?< 0,001). Aeei?enoaiiy CIEIE, ni?eyth/e noaaieicaoei? iieacieeia eiaaoeieiai/ieo aeineiae-aeaiue, iiia?aaeaeaei eeiii/io iaiioanoaoeith iaoieiai? o 86,6% aeiiie, i?e i?ecia/aiii anii?i-io - o 60,0% (?<0,05). Ii?iaiyiiy iniaeeainoae ia?aaiao ?iaeia iieacaei, ui I?II o aeiiie II-IA cono?i/aa-ny a 6,7%, ui iaeaea a 2 ?ace ?iaeoa (?< 0,05), iiae a II-AI. Caaaeueia e?iaiao?aoa a iieiaao iiney i?iaaaeaiii oioiaiioa?aiii noaiiaeea 258,4±16,8 ie, a oie /an ye o aeiiie, ui io?eioaa-ee o?aaeeoeieia eieoaaiiy - 318,1±14,5 ie (?<0,05). A ?acoeueoaoi i?iaaaeaiiai eieoaaiiy c aeei?enoaiiyi CIEIE aiaeii/aii iie?auaiiy noaio aioo?ioiueioo?iaiiai ieiaea. Oae, ca aeaieie ciaiioiuei? ea?aeiooieia?aoi? ioeiiea noaio ieiaea ca oeaeith Fischer iiney eo?no CIEIE a I-IA noaiiaeea 8,97±0,51 aaea, a iaia?aaeiaei? eieoaaiiy - 7,63±0,42 (?<0,05), ui a 1,3 ?ace aeua. A I-IA ca?a?no?iaaii iieiioaiiy noaio aeioae i?e ia?iaeaeaiii, ioeiiaiiio ca oeaeith Aiaa?, a ii?iaiyiii c a?oiith aeioae iaoa?i yeeo io?eioaaee o?aaeeoeieia eieoaaiiy. Oae, ioeii-ea iiaiia?iaeaeaieo ia 1-e oaeeeii aeeooy o aeiiie, yei io?eioaaee eaca?io oioiaiioa?aiith, aoea ia 0,69 aaee aeua, i?ae a I-AI (6,95±0,14 aaea i?ioe 6,26±0,18 aaea; ?<0,01), a ia 5-e oa.-7,98±0,12 - a AI 6,94±0,47, ui ia 1,04 aaee (?<0,05) aeua, iiae a I-AI. Iieaciee ?aiiueii iai-iaoaeueiii nia?oiinoi a I-IA noaiiaea 129‰, a a I-AI - 200‰, ui a 1,6 ?aca iaioa. Aiaeic aio?iiiiao?e/ieo aeaieo, iniaeeainoae ia?aiai-ineoi/iiai ?icaeoeo aeioae oa ?o caoai?thaaiinoi ia i?ioyci ia?oeo 6 iinyoeia aeeooy iieacaa, ui aeioe aiae iaoa?ia I-IA oa aei-iie I-AI ?icaeaaeenue i?aeoe/ii iaeiaeiai, iaeiae iaiiaeyoa, iaoa?i yeeo io?eioaaee CIEIE, ?iaeoa oai?iee i caaaeueia eieueeinoue caoai?iaoeo aeioae a I-AI aoea a 2,1 ?ace aieueoith, iiae a I - IA (?<0,02). AENIIAEE 1. I?e ia?aae/anieo iieiaao, oneeaaeiaieo ia?aae/aniei ?ic?eaii ieiaeieo iaieiiie, aeieea? iioaineoieaoeiy aioo?ioiueinoaeeiiiai o?iiaiooai?aiiy, i?i ui naiae/eoue iiaeaeuai-iy aeoeaiinoi noaeeiii-o?iiaioeeoa?ii?, eiaaoeyioii? oa oia?iiieioe/ii? eaiie aaiinoaco, oea ni?ey? caieueoaiith ia'?io e?iaiao?aoe a iieiaao. 2. Cnoae oiciieiai/ii? ?iaiiaaae nenoaie aaiieiaaoeyoei? a a?e ciaioaiiy e?eueeino? o?iiaioeeo?a, i?aeaeuaiiy eaoaioii? aa?aaaoe??, eooa aa?aaaoe??, ??cieoe? iioe/ii? u?eueiino? ieacie, eiioeaio?aoe?? o?a??iiaaio, aeoeaaoe?? AO-???, nei?i/aiiy /ano ?aeaeueoeeo?eaoe?? ieac-ie, i?io?iia?iiaiai oa o?iia?iiaiai /ano, o?a??iie?co aoaeiaoe?i?a, iayai?noue iiceoeaieo oano?a ia?aeiaaoeyoe?? ? aeieeiii/ieie iciaeaie caa?ice ia?aae/anieo iieiaia. 3. Canoinoaaiiy iecueeiiioaineaiiai eaca?iiai ii?iiiithaaiiy e?iai a neiiea?ioeae-iie ciii ci?ey? iiaeaeuaiith eieueeinoi o?iiaioeeoia, aenioe oa /ano eaoaioiii aa?aaaoei?, i?i-o?iiaiiiaiai i o?iiaiiiaiai /ano, cieaeaiith ooieoeiiiaeueiii aeoeaiinoi o?iiaioeeoia (eooa aa?aaaoeii, ?icieoei iioe/iii uieueiinoi ieacie), aeoeaiinoi AO-III, /ano oia?iiieico aoaeiaoei-iia, nooiaith ae?aaeaiinoi oanoia ia?aeiaaoeyoeii, ui iieiioo? aaeaioaoeieii oa eiiiainaoi?ii iiaeeeainoi aaiinoaco i?e ia?aae/anieo iieiaao, oneeaaeiaieo ia?aae/aniei ?ic?eaii ieiae-ieo iaieiiie. 4. I?iaaaeaiiy eaca?iii oioiaiioa?aii? i?e ia?aae/anieo iieiaao c ia?aae/aniei ?ic-?eaii ieiaeieo iaieiiie ciaioo? caaaeueio e?iaiao?aoo a iieiaao a 1,2 ?ace. 5. Aeeth/aiiy ?ic?iaeaiiai niiniao ei?aeoei? ii?ooaiue aaiinoaco a eiiieaen eieo-aaeueieo caoiaeia i?e caa?ici ia?aae/anieo iieiaia ni?ey? ii?iaeicaoei? oiiono iaoee, iieii-oaiith noaio aioo?ioiueioo?iaiiai ieiaea, cieeiaiith eeiii/ieo iciae caa?ice ia?a?eaaiiy aaaioiinoi. 6. Cai?iiiiiaaiee iaoiae ei?aeoei? ii?ooaiue aaiinoaco i?e aeieeiii/ieo i?iyaao ca-a?ice ia?a?eaaiiy aaaioiinoi o 86,6% aeiiie iiia?aaeaeo? iaiioanoaoeith iaoieiai?. 7. I?ioieaeoe/ia eaca?ia oioiaiioa?aiiy a III o?eiano?i aaaioiinoi ni?ey? ciaioai-ith a 1,9 ?ace oneeaaeiaiue iieiaia ia?aae/aniei aeeeooyi iaaeieiieiaeiii aiaee. 8. Canoinoaaiiy ciaiioiueiai iecueeiiioaineaiiai eaca?iiai ii?iiiithaaiiy e?iai c iaoith ei?aeoei? aaiinoaciieiai/ieo ciii iiney ia?aae/aniiai aeeeooy iaaeieiieiaeii? aiaee i?e iaaeiiioaiie aaaioiinoi ni?ey? cieaeaiith ia?iiaoaeueii? nia?oiinoi a 1,6 ?ace (c 200‰ aei 129‰), caoai?thaaiinoi aeioae a ia?oi 6 iinyoeia aeeooy - a 2,1 ?ace. I?AEOE*II ?AEIIAIAeAOeII 1. Aeey aecia/aiiy a?oie ?eceeo ii ia?aae/aniei iieiaai oa ia?aae/aniiio ?ic?eao iaaeieiieiaeieo iaieiiie ?aeiiaiaeoaaoe aeiieai a eiioei II o?eiano?a aaaioiinoi ?icoe?aia aaiinoaciieiai/ia ianoaaeaiiy aeey aeyaeaiiy cnoaia a nenoaii aaiieiaaoeyoei? ye aeieeiii/ii? iciaee caa?ice ia?a?eaaiiy aaaioiinoi. 2. I?e ia?aae/anieo iieiaao c ia?aae/aniei ?ic?eaii iaaeieiieiaeieo iaieiiie c ia-oith noaaieicaoei? nenoaie aaiieiaaoeyoeieiiai aaiinoaco oa iiia?aaeaeaiith iaoieiai/ii? e?i-aiao?aoe a iieiaao canoiniaoaaoe ciaiioi? iecueeiiioaineaia eaca?ia ii?iiiithaaiiy e?iai aeiaaeeiith oaeei 0,63iei a aacia?a?aiiio ?aaeeii ii?iiiithaaiiy, iiooaeiinoth 10-12iAo, /anii aeniiceoeii 600 n ia i?ioyci 3-o aeia. 3. Aaaioiei, c caa?icith ia?aae/anieo iieiaia a eiiieaeni caa?iaath/i? oa?aii? aeey iiae-aeuaiiy eiiiainaoi?ieo iiaeeeainoae nenoaie aaiinoaco i?iaiaeeoe ciaiioi? iecueei-iioaineaia eaca?ia ii?iiiithaaiiy e?iai a iaeanoi neiiea?ioeaeii? ciie a aacia?a?aiiio ?a-aeeii, aeiaaeeiith oaeei 0,63iei, iiooaeiinoth 10iAo, /anii aeniiceoeii 300 n ia i?ioyci 5-7 aeia. 4. Aeueoa?iaoeaiei iaoiaeii i?ioieaeoeee aaiinoaciieiai/ieo ii?ooaiue ? i?ecia-/aiiy anii?iio: i?e caa?ici ia?aae/anieo iieiaia - 0,25a iaeei ?ac ia aeiao ia i?ioyci 3-o oeae-iia, i?e ia?aae/anieo iieiaao c ia?aae/aniei ?ic?eaii ieiaeieo iaieiiie - 0,25a o?e ?ace ia aeiao ia i?ioyci 3-5 aeia. NIENIE ?IAIO, IIOAEIEIAAIEO CA OAIITH AeENA?OAOeI? 1. Ninoiyiea nenoaiu aaiinoaca i?e oa?ica i?aaeaeaa?aiaiiuo ?iaeia //Aanoiee i?i-aeai aeieiaee e iaaeeoeeiu.-1997.- ?31.-N.54-60. 2. Ei??aeoeey eciaiaiee nenoaiu aaiinoaca i?e oa?ica i?aaeaeaa?aiaiiuo ?iaeia io-o?i ia?oaeiiai ieceieioaineaiiai eaca?iiai iaeo/aiey e?iae //Aanoiee i?iaeai aeieiaee e iaaeeoeeiu.-1997.-? 31.-N.48-54. 3. Niinia i?ioieaeoeee eiaaoeiiaoe/ieo e?iaioa/ i?e ia?aae/anieo iieiaao (iaoaio Oe?a?ie ia aeiaoiae ?21344A aiae 02.12.1997?.). 4. Iioeiicaoeiy iieacieeia cenoaie aaiinoaco o aaaioieo a?oie ?eceeo ii ?icaeoeo e?iaioa/i //Oace aeiiiaiaeae O c'?caeo aeooa?ia-aiiaeieiaia Oe?a?ie.-Iaeana.-1996.-N.28. (niia-aaoi?e O.TH.Eyoianueea, I.A.Iaea?ia). 5. Iniaeeainoi nenoaie aaiinoaco i?e ia?aae/anieo iieiaao //Oace aeiiiaiaeae O c'?caeo aeooa?ia-aiiaeieiaia Oe?a?ie.-Iaeana.-1996.-N.30. 6. Ia?aae/anii ?iaee ye i?e/eia ia?iiaoaeueii? nia?oiinoi //Oace aeiiiaiaeae eiioa?ai-oei? iieiaeeo a/aieo.-Aiiieoey.-1995.-N.18-19. 7. E aii?ino i i?e/eiao i?aaeaeaa?aiaiiuo ?iaeia //Oace aeiiiaiaeae iaoeiai? eiioa-?aioei?, i?enay/aii? 75-?i//th i?ioani?a I.A.Aeoae/aiea i 20-?i//th eaoaae?e oaeoeueoaonueei? oa?aii? ,,Aeooaeueii ieoaiiy eeiii/ii? iaaeeoeeie".-Iieoaaa.-1994.-N.19-20. (niiaaa. A.I.A?i-iiaa, A.A.Aiaeaee?anueea). 8. Ei?aeyoeieiee ca'ycie iiae e?iaiiinoa/aiiyi aieiaiiai iiceo aeiiie oa noaiii aio-o?ioiueioo?iaiiai ieiaea i?e iiciio oieneeicao aaaioieo //Oace aeiiiaiaeae iaoeiai-i?aeoe/-ii? eiioa?aioei? aeooa?ia-aiiaeieiaia Oe?a?ie. Aeiiaoeuee.-1994.-N.19-20. (niiaaaoi?e I.A.AEaa-/aiei, A.A.Aeoae/aiei). AIIOAOeI? Ianoa?aiei E.A. "I?ioieaeoeea aaiinoaciieiai/ieo ii?ooaiue i?e ia?aae/anieo iieiaao, oneeaaeiaieo ia?aae/aniei ?ic?eaii iaaeieiieiaeieo iaieiiie". - ?oeiien. Aeena?oaoeiy ia caeiaooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoeiaeue-iinoueth 14.01.01 - aeooa?noai i aiiaeieiaiy. Oa?eianueeee aea?aeaaiee iaaee/iee oiiaa?ne-oao. Oa?eia, 1998. Aeena?oaoeiy i?enay/aia aea/aiith noaio nenoaie aaiinoaco i?e ia?aae/anieo iieiaao oneeaaeiaieo ia?aae/aniei ?ic?eaii ieiaeiaeo iaieiiie, caa?ici ia?aae/anieo iieiaia oa i?e caa?ici ia?a?eaaiiy aaaioiinoi. Iieacaia iaiaoiaeiinoue i?iaaaeaiiy ?icoe?aiiai aaiinoacii-eiai/iiai aeineiaeaeaiiy o aaaioieo a II oa III o?eiano?ao aaaioiinoi. ?ic?iaeaiee iiaee niinia i?ioieaeoeee ii?ooaiue nenoaie aaiinoaco i?e ia?aae/anieo iieiaao, oneeaaeiaieo ia?aae/an-iei ?ic?eaii iaaeieiieiaeieo iaieiiie, oeyoii aieeao ciaiioiueiai iecueeiiioaineaiiai eaca?iiai ii?iiiithaaiiy e?iai. Eeth/iai neiaa: aaiinoac, eaca?ia ii?iiiithaaiiy, ia?aae/anii iieiae, ia?aae/aniee ?ic?ea iaaeieiieiaeieo iaieiiie. Ianoa?aiei E.A. I?ioeeaeoeea aaiinoaceieiae/aneeo ia?ooaiee i?e i?aaeaea-a?aiaiiuo ?iaeao, ineiaeiaiiuo i?aaeaeaa?aiaiiui ?ac?uaii ieiaeiuo iaiei/ae. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii nia-oeeaeueiinoe 14.01.01 – aeooa?noai e aeiaeieiaey. Oa?ueeianeee ainoaea?noaaaiiue iaaeeoeeineee oieaa?neoao. Oa?ueeia, 1999. Aeenna?oaoeey iinayuaia eco/aieth nenoaiu aaiinoaca i?e oa?ica i?aaeaeaa?aiaiiuo ?iaeia, i?aaeaeaa?aiaiiuo ?iaeao e i?aaeaeaa?aiaiiuo ?iaeao, ineiaeiaiiuo i?aaeaeaa?aiaiiui ?ac?uaii ieiaeiuo iaiei/ae. Eeeie/anee ianeaaeiaaii 193 aa?aiaiiuo e ?iaeaieoeu. Ia?aeeaeueii n iauaeeeie/an-eeie enneaaeiaaieyie i?iaiaeeeinue eco/aiea aaiinoaceieiae/aneeo iieacaoaeae: o?iiaioee-oa?iiai, i?ieiaaoeyioiiai e oea?eiieeoe/aneiai caaiueaa aaiinoaca. Enneaaeiaaiey auyae-ee, /oi i?e i?aaeaeaa?aiaiiuo ?iaeao n i?aaeaeaa?aiaiiui ?ac?uaii ieiaeiuo iaiei/ae eiaao ianoi iiauoaiea ooieoeeiiaeueiie aeoeaiinoe o?iiaioeeoia e aeoeaaoeey ninoaeenoio?iiai-oeeoa?iiai caaia aaiinoaca. Eco/aiea eiaaoeyoeeiiiiai caaia aaiinoaca o yoeo aeaiuei iiea-caei iaee/ea aeoeaaoeee i?ioeannia naa?ouaaiey e?iae ii aiaoiaio iaoaiecio, /oi ?anoeaia-ii eae i?iyaeaiea iiiaaeaiey a ninoaeenoia ?onei oeaiaaiai o?iiaiieanoeia aneaaenoaea i?aaeaeaa?aiaiiiai eceeoey ieieiieiaeiuo aiae. I?e yoii iiauoaeanue aeoeaiinoue oea?eii-eeoe/aneiai caaia nenoaiu aaiinoaca. Yoaiieiaue e -iaooieiaue oanou ii?aaeaeyeenue oieueei o aeaiuei n i?aaeaeaa?aiaiiui eceeoeai ieieiieiaeiuo aiae i?e iaaeiiioaiiie aa?a-iaiiinoe. Iieo/aiiua ?acoeueoaou aeaiiino?e?iaaee iaee/ea o aeaiuei n i?aaeaeaa?aiaiiu-ie ?iaeaie e i?aaeaeaa?aiaiiui ?ac?uaii ieiaeiuo iaiei/ae ia?aie oacu o?iie/aneiai AeAN-neiae?iia. Yoi yaeeinue iainiiaaieai aeey ?ac?aaioee iaoiaea ia?oaeiiai ieceieioai-neaiiai eaca?iiai iaeo/aiey e?iae a neiiea?ioeaeiie ciia n oeaeueth i?ioeeaeoeee e ei??ae-oeee ia?ooaiee aaiinoaca i?e oa?ica i?aaeaeaa?aiaiiuo ?iaeia e i?aaeaeaa?aiaiiuo ?iaeao n i?aaeaeaa?aiaiiui eceeoeai ieieiieiaeiuo aiae. I?iaaaeaiea eo?na eaca?iie oioiaeioa?aiee a eiiieaena n o?aaeeoeeiiiui ea/aieai i?e i?aaeaeaa?aiaiiuo ?iaeao n i?aaeaeaa?aiaiiui eceeoeai ieieiieiaeiuo aiae a 29-36 ia-aeaeue aa?aiaiiinoe niinianoaiaaei iiauoaieth eiee/anoaa o?iiaioeeoia, nieaeaieth eo ooieoeeiiaeueiie aeoeaiinoe ii n?aaiaieth n a?oiiie aeaiuei, iieo/aaoeo eiiieaenioth oa?aieth n anie?eiii. Oaeea aea eciaiaiey ioia/aeenue i?e eco/aiee eiaaoeyoeeiiiiai aa-iinoaca. Iinea ia?oaeiiai ieceieioaineaiiai eaca?iiai iaeo/aiey e?iae nieaeaeny iieaca-oaeue aeoeaiinoe aioeo?iiaeia III ii n?aaiaieth n aai cia/aieai aei ia/aea ea/aiey. A a?oi-ia aeaiuei, iieo/aaoeo anie?ei, yoio iieacaoaeue i?aeoe/anee ia eciaiyeny. N?aaiaiea aeaenoaey ia aaiinoac anie?eia e iao?aaeeoeeiiiie oa?aiee iieacae, /oi iiae aeeyieai ii-neaaeiae i?ienoiaeeee aeinoiaa?iia iiauoaiea a?aiaie oea?eiieeca yoaeiaoeeiia. Oaeei ia?acii, i?iaaaeaiea eaca?iie oioiaeioa?aiee niinianoaiaaei ii?iaeecaoeee iieacaoaeae aaiinoaca o aeaiuei n i?aaeaeaa?aiaiiuie ?iaeaie e i?aaeaeaa?aiaiiui eceeoeai ieiei-ieiaeiuo aiae. Eco/aiea aaiinoaceia?aii i?e aeieeeie/aneeo i?eciaeao oa?icu i?aaeaeaa?aiaiiuo ?iaeia naeaeaoaeuenoaiaaei ia aeoeaaoeee o yoeo aeaiuei nenoaiu naa?ouaaiey e?iae e oea?e-iieeca, /oi iicaieeei ?anniao?eaaoue auyaeaiiua eciaiaiey eae aeieeeie/aneea ia?ea?u oa?icu i?aaeaeaa?aiaiiuo ?iaeia. I?eiaiaiea ia?oaeiiai ieceieioaineaiiai eaca?iiai iaeo/aiey e?iae niinianoaiaaei i?eaeeaeaieth aaiinoaceieiae/aneeo iieacaoaeae o aeai-uei n oa?icie i?aaeaeaa?aiaiiuo ?iaeia e oaeiaui o caei?iauo aa?aiaiiuo aiaeiae/iuo n?i-eia. A a?oiia aeaiuei, iieo/aaoeo anie?ei, ioia/aiu oieueei oaiaeaioeee e ii?iaeecaoeee aaiinoaceia?aii i?aeiouanoaaiii ca n/ao iieacaoaeae ninoaeenoi-o?iiaioeeoa?iiai caaia. Aiaeec iniaaiiinoae oa/aiey ?iaeia a ianeaaeoaiuo a?oiiao iieacae, /oi i?iaaaeaiea eaca?iie oioiaeioa?aiee i?e i?aaeaeaa?aiaiiuo ?iaeao n i?aaeaeaa?aiaiiui ?ac?uaii ieiae-iuo iaiei/ae oiaiueoaao /anoioo aeiioiie/aneeo e?iaioa/aiee e iauoth e?iaiiioa?th a ?iaeao. I?eiaiaiea ?ac?aaioaiiiai niiniaa ei??aeoeee ia?oaiee aaiinoaca a eiiieaena ea/aaiuo ia?ii?eyoee i?e oa?ica i?aaeaeaa?aiaiiuo ?iaeia ii?iaeeciaaei oiion iaoee, oeo/oaei ninoiyiea aioo?eoo?iaiiai ieiaea e eeeaeaee?iaaei eeeie/aneea i?eciaee oa?icu i?a?uaaiey aa?aiaiiinoe, a i?e iaee/ee aeieeeie/aneeo i?eciaeia oa?icu i?aaeaeaa?aiai-iuo ?iaeia i?aaeoi?aaeaeaao iaieoanoaoeeth iaoieiaee. Iieacaei, /oi eaca?iay oioiaeii?ioe-eaeoeea nieaeaao /anoioo i?aaeaeaa?aiaiiuo ?iaeia n i?aaeaeaa?aiaiiui eceeoeai ieieiieiae-iuo aiae. Eeth/aaua neiaa: aaiinoac, eaca?iia iaeo/aiea, i?aaeaeaa?aiaiiua ?iaeu, i?aaeaeaa?a-iaiiue ?ac?ua ieiaeiuo iaiei/ae. Nesterenko L.A. "Prophylaxis of hemostasiological violations in premature deliery complicated by premature laceration of fetal membra-nes". A manuscript. A thesis for a Candidate of medical sciences degree on the specia-lity - 14.01.01. - obstetrics and gynecology. Kharkov states medical university. Kharkov, 1998. The work is devoted to the study of homeostasis system in premature deli-very complicated by premature laceration of fetal bladder, threat of premature delivery and in case of the threat of abortion. The necessity of wide hemosta-siological investigation inpatients on the II and III trimester of pregnancy is shawn. The was worked out new method of prophylaxis of hemostasiological violations in premature delivery complicated by premature laceration of fetal bladder by means of the influence of the outer lowintensive laser irradiation of blood. Key words: homeostasis, laser irradiation, premature delivery, premature laceration of fetal membranes.

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