?INOEOOO AIAeIE?EIIEIA?? OA IAI?IO ?A*IAEI

?i. A.I. Eii?na?aiea AII Oe?a?ie

OO?*EIA Naioeaia Iai?iaia

OAeE 612.661-092-07-053.6

I?I O*ANOUe IAEAOII?IO O NOAOAAIIO AeIC??AAII? ? OI?IOAAII?
CAO?EIEE NOAOAAIAI ?ICAEOEO OEIIOe?A-I?AeE?OE?A

14.01.14 — aiaeie?eiieiaiy

AAOI?AOA?AO

aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeoaoa iaaee/ieo iaoe

Ee?a -1999

Aeena?oaoe?y ? ?oeiienii.

?iaioa aeeiiaia a Oe?a?inueeiio iaoeiai-aeine?aeiiio ?inoeooo? ioi?iie
caei?ia’y ae?oae oa i?aee?oe?a IIC Oe?a?ie, i. Oa?e?a.

Iaoeiaee ea??aiee:
aeieoi? iaaee/ieo iaoe, i?ioani? Ie?oiaa

Ieaia ?ai??aia,Oe?a?inueeee IAe? ioi?iie

caei?ia’y ae?oae oa i?aee?oe?a, canooiiee

aee?aeoi?a c iaoeiai? i?aoei, caaiaeoth/a

eaai?aoi???th a?eiai? aiaeie?eiieia??

Io?oe?ei? iiiiaioe:

· aeieoi? iaaee/ieo iaoe Eo/eoeueeee ?aaai Aaneeueiae/, ?inoeooo
aiaeie?eiieia?? oa iai?io ?a/iaei ?i. A.I. Eii?na?aiea AII Oe?a?ie,
caaiaeoaa/ aiaeaeieo ee?i?/ii? aiae?ieiai?

· aeieoi? iaaee/ieo iaoe Aieei Ieeiea ?aaiiae/, ?inoeooo o?ieiai? oa
iao?ieiai? AII Oe?a?ie, aiaeaeie naenieiai? oa aiae?ieiai?, aieiaiee
iaoeiaee niia?iaioiee

I?ia?aeia onoaiiaa: Oe?a?inueeee IAeI oa?iaeioa?aii? aiaeie?eiieo
caoai?thaaiue, eaai?aoi?iy aiae?ieiai? IIC Oe?a?ie, i. Oa?e?a

Cao?no a?aeaoaeaoueny 26 aeiaoiy 1999 ?. i 13 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.558.01 c
aiaeie?eiieia?? a ?inoeooo? aiaeie?eiieia?? oa iai?io ?a/iaei ?i.
A.I.Eii?na?aiea AII Oe?a?ie (252114, Ee?a-114, aoe. Aeoai?iaenueea, 69)

C aeena?oaoe??th iiaeia iciaeiieoenue o aiaeiioaoei ?inoeoooo
aiaeie?eiieia?? oa iai?io ?a/iaei ?i. A.I. Eii?na?aiea AII Oe?a?ie
(252114, Ee?a-114, aoe. Aeoai?iaenueea, 69).

Aaoi?aoa?ao ?ic?neaiee “24” aa?aniy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

aeieoi? a?ieia?/ieo iaoe
Eaeeinueea E.I.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Caa?aaeaiiy ?ai?iaeoeoeaiiai iioaioe?aeo ianaeaiiy
– iaeia c ia?oi/a?aiaeo iaaeeei-nioeiaeueieo caaaeaiue a Oe?a?i?,
oni?oia ae??oaiiy yeiai iaiiaeeeai aac caaaeueiiai aecia/aiiy i?e/ei oa
iaoaieci?a ii?ooaiiy ooieoe?? noaoaai? nenoaie ia aoaiao ?o oi?ioaaiiy,
?ic?iaee i?iaiico iane?aee?a oeeo ii?ooaiue oa aecia/aiiy aaeaeaaoieo,
a?eueo aoaeoeaieo e?eoaaeueieo iaoiae?a.

Ciaioaiiy ai?iiiaeueii? aeoeaiino? aiiaae o i?aee?oeiaiio a?oe?, yea
i?eaiaeeoue aei cao?eiee noaoaaiai aeic??aaiiy oeiioe?a, yaeua aeineoue
?iciianthaeaeaia. Ca ?acoeueoaoaie ai?aeai?ieia?/ieo aeine?aeaeaiue,
cao?eiea noaoaaiai ?icaeoeo (CN?), yea ia coiiaeaia ia?aeiiei oa
aoi?eiiei a?iiaiiaaeeciii, cono??/a?oueny o 2-4% oeiey??a Oe?a?ie
(E?aa/aiei, Ni??iia, 1989; Nooeie e niiaaao., 1991; Ei?ai?a e niiaaao.,
1995).

O?eaaeee /an CN? ?icoe?ithaaee ye i?iya eiinoeoooe?iiaeueieo
iniaeeainoae noaiiaeaiiy ?ai?iaeoeoeaii? nenoaie, ui ia iio?aaothoue
aeoeaiiai e?eoaaiiy. I?ioa aea/aiiy ai?iiiaeueiiai noaoono i?aee?oe?a c
oiia?eueiaiei ia?aa?aii ioaa?oaoo aeicaieeei anoaiiaeoe, ui CN?
noi?iaiaeaeo?oueny cia/ieie ci?iaie ooieoe?iiaeueii? aeoeaiino?
a?iioaeaii-a?iio?ca?ii-aiiaaeii? nenoaie, ii?ooaiiyi oa?aeoa?o cai?ioieo
ca’yce?a i?ae eaieaie oe??? ?aeeii? ooieoe?iiaeueii? nenoaie (Nei?iaeie,
Naa/aiei, 1984; Eaaaae?a, 1985; Ieaoiaa, 1986; Aeai/aiei e niiaaao.,
1988,1991; Ca?oaiia e niiaaao., 1989; Aa?eianueea, 1992; Rebuffel,
Vagner, 1991; Albanes, Stanhope,1995), ye? i?e a?aenooiino? aaeaeaaoii?
ei?eaoth/i? oa?ai?? noathoue i?e/eiith oi?ioaaiiy ia o?eueee
?ioaioee?cio ? aacie?aeiino? ii aeinyaiaii? oa?oeeueiiai a?eo, aea ?
a?aeoeeaiue o ineoiaiioe?ei?e noa?? i?aee?oe?a, niiaoe/iiio caei?ia’?
(Aeoie, 1981; Aeaaeeiaa, 1981; Aaii?eiaa e niiaaao., 1981, 1987;
Oeeoeineee, 1990; AEoeianeee, 1997; Na?aia e niiaaao., 1997; Nhapmen,
1985; Rosenfield, 1990) , cieaeaiiy ?o i?aoeacaeaoiino? ? iia??oaiiy
nioe?aeueii? aaeaioaoe?? (A?oai/oe, 1984; A?aociaa e niiaaao., 1995,
1996; AEaeaiiaa, 1995).

Iacaaaeath/e ia cia/i? oni?oe, aeinyaioo? a inoaii? aeanyoee?ooy i?e
aea/aii? iaoiaaiaoe/ieo iaoai?ci?a, ui eaaeaoue a iniia? CN?, aeioaia?
caeeoa?oueny aeeneooaaaeueiei ieoaiiy i?i i?noea ai?o?ca ? eiai ai?iiio
— iaeaoii?io a i?ioean? oi?ioaaiiy aeaii? iaoieia?? (Ie?oiaa, Oa?/aiei,
1992; Gupta et al.,1982,1986; Attanasio et al., 1983; Waldhauser et al.,
1989,1991,1997). Iiaeai? a iayaieo ?iaioao aeniiaee i?i o/anoue
iaeaoii?io a noaoaaiio aeic??aaii? ? oi?ioaaii? ii?ooaiiy ooieoe??
noaoaaeo caeic o oeii/ee?a aacothoueny, o a?eueoino? aeiaaee?a, ia
?acoeueoaoao, io?eiaieo i?e aeine?aeaeaii? ae?ae ia/eneaiieo a?oi
iaoe??io?a, aac o?aooaaiiy oee?eaaeieo ?eoi?a ooieoe?iiaeueii?
aeoeaiino? ai?o?ca (Silman et al., 1979; Luboshitzky et al., 1995,
1997).

Aiaeii/an, aiae?c aene?aoe?? iaeaoii?io ia aoaiao noaoaaiai aeic??aaiiy
i?e o?c?ieia?/iiio ? iaoieia?/iiio eiai ieei? c o?aooaaiiyi iiaeeeaeo
aeiaiaiai ? ??/iiai ?? ?eoi?a aeicaieea ae ia o?eueee ooi/ieoe i?noea
iaeaoii?io a iae?iai?iiiaeueiiio eiio?ie? oeueiai i?ioeano a /ieia?/iio
i?aai?ci?, aea e oaeineiiaeeoe iaoiaee i?iaiicoaaiiy noaiiaeaiiy
ooieoe?? ?ai?iaeoeoeaii? nenoaie, ?aiith ae?aaiinoeeo ? caniae ei?aeoe??
aeayeeo oi?i ii?ooaiiy noaoaaiai aeic??aaiiy.

Aeooaeuei?noue ?icaeyiooi? aeua i?iaeaie aecia/eea iai?yiie ? iaoo
aeaiiai aeine?aeaeaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?eia
?iaioa aeeiiaia o iaaeao eiiieaenii? oaie: “?ic?iaea oaoiieiai?
?aaaieioaoei? oeiioeia-iiaeeioeia c ii?ooaiiyi noaoaaiai ?icaeoeo” (?
Aea?aeaaii? ?a?no?aoe?? 0194 023941), yea ?ic?iaeyeanue a Oe?a?inueeiio
IAe? ioi?iie caei?ia’y ae?oae oa i?aee?oe?a (i.Oa?e?a) caiaeii c
Iaoeiiiaeueiith i?ia?aiith “Ieaioaaiiy nii’?”.

Iaoa aeineiaeaeaiiy — iiaeeaeaiiy oyaeaiue i?i o/anoue iaeaoii?io a
iaoai?ciao noaiiaeaiiy ooieoe?? /ieia?/i? noaoaai? nenoaie, oi?ioaaii?
cao?eiee noaoaaiai aeic??aaiiy o oeiioe?a ? oaeineiiaeaiiy ?oiueiai
e?eoaaiiy.

Iniiai? caaaeaiiy ?iaioe:

1. aea/eoe a?eiao aeeiai?eo aene?aoe?? iaeaoii?io o caei?iaeo in?a
/ieia?/i? noao? c o?aooaaiiyi nooiaiy ?oiuei? a?ieia?/ii? c??eino?,
aeiaiaeo ? ??/ieo ?eoi?a;

2. aeaoe ee?i?ei-ai?iiiaeueio oa?aeoa?enoeeo oeiioeyi ?c CN?;

3. aea/eoe iniaeeaino? aene?aoe?? iaeaoii?io o oeiioe?a ?c CN?;

4. i?iaiae?coaaoe oa?aeoa? aca?iia?aeiinei iaeaoii?io ?c noaoaaeie
noa?i?aeaie ? aiiaaeio?iiieie ai?iiiaie ia aoaiao noaoaaiai aeic??aaiiy
i?e o?c?ieia?/iiio ieei? ioaa?oaoo oa i?e CN?;

5. oai?aoe/ii iaa?oiooaaoe, ?ic?iaeoe e ai?iaoaaoe iaoiae e?eoaaiiy CN?,
ui ei?eao? ooieoe?iiaeueio aeoeai?noue ai?o?ca.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoaoia. Ia i?aenoaa? aeine?aeaeaiiy
ai?noo iaeaoii?io, aiae?co eiai aca?iia?aeiinei ?c noaoaaeie noa?i?aeaie
? aiiaaeio?iiieie ai?iiiaie ia aoaiao noaoaaiai aeic??aaiiy /ieia?/iai
i?aai?cio aeiaaaeaia i?e/aoi?noue ai?o?ca?iiai ai?iiio aei iaoai?ci?a,
ui eiio?ieththoue noaiiaeaiiy /ieia?/i? ?ai?iaeoeoeaii? nenoaie.
Anoaiiaeaii iniaeeaino? a?eiai? aeeiai?ee ai?noo iaeaoii?io, ci?ia eiai
aca?iica’yce?a c aiiaaeio?iiieie ? noaoaaeie ai?iiiaie i?ioyaii
noaoaaiai aeic??aaiiy. Aia?oa iieacaia ?nioaaiiy ??/iiai ?eoio
aene?aoe?? iaeaoii?io o caei?iaeo oeiioe?a ? aecia/aii aieea naciio
?ieo ia oa?aeoa? aeiaiaiai ?eoio.

Aeyaeaii iaai? ci?ie iaeaoii?ii?iaeoeoth/i? aeoeaiino? ai?o?ca i?e
cao?eioe? noaoaaiai ?icaeoeo o oeiioe?a. Aeiaaaeaii, ui o oeiioe?a ?c
CN? ai?no iaeaoii?io a na/? ia a?aeiia?aea? aeinyaiooiio ??aith
noaoaaiai aeic??aaiiy, ci?iaiee oa?aeoa? ai?o?ca?ii-a?iio?ca?ii-aiiaaeeo
aca?iia?aeiinei, ? iniaeeaino? o ??/iiio ?eoi? aene?aoe?? iaeaoii?io.

Oai?aoe/ii iaa?oiooaaia aeioe?euei?noue canoinoaaiiy o oeiioe?a ?c CN?
i?e ??ai? aene?aoe?? iaeaoii?io, yeee ia?aaeuo? naciiio a?eiao ii?io,
iaoiaeo e?eoaaiiy, ni?yiiaaiiai ia cieaeaiiy i?iaeoeoe?? iaeaoii?io
ai?o?cii.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoaoia. ?ic?iaeaii o?c?ieia?/i?
ii?ie ai?noo iaeaoii?io ia ??cieo aoaiao noaoaaiai aeic??aaiiy.
Aeiaaaeaia iaiao?aei?noue a?aoiaoaaoe i?e aeine?aeaeaii? iaeaoii?io ia
o?eueee ianii?oiee a?e, nooi?iue a?ieia?/ii? c??eino?, aea e i?nyoeue
(nacii), eiee i?iaiaeeoueny aeine?aeaeaiiy.

Iieacaii, ui aenieee ??aaiue iaeaoii?io a na/? ia ?aii?o aoaiao
noaoaaiai aeic??aaiiy iiaeia ?icaeyaeaoe ye iaeei ?c /eiiee?a oi?ioaaiiy
CN?.

Aia?oa aeey e?eoaaiiy CN? o oeiioe?a ?ic?iaeaiee ? ai?iaiaaiee
iaiaaeeeaiaioiciee iaoiae e?eoaaiiy (iiaeiaaeaiiy na?oeiaiai aeiy aei 16
aiaeei a in?iiuei-ceiiaee ia??iae), ui caaacia/o? i?eai?/aiiy
i?iaeoeoe?? iaeaoii?io (Aea?aeiaoaio Oe?a?ie ? 97073955).

Iniaenoee aianie caeiaoaa/a. Aeena?oaoeieio ?iaioo aoei aeeiiaii iiae
/an iaa/aiiy a anii?aioo?i. Aaia c?iaeea iaoaioii-?ioi?iaoe?eiee iiooe,
aiae?c iaoeiai? e?oa?aoo?e c aeine?aeaeoaaii? i?iaeaie. Aaoi?
aeena?oaoe?? i?iaiaeeea i?aea?? oaiaoe/ieo oai?eo, naiino?eii aeeiiaea
ianoaaeaiiy caei?iaeo oeii/ee?a ? oeiioe?a oa iiaeeioeia ?c CN?,
?ic?iaeea ? ai?iaoaaea iiaee iaiaaeeeaiaioiciee iaoiae e?eoaaiiy,
i?iaaea noaoenoe/ia ii?aoethaaiiy ?acoeueoao?a aeine?aeaeaiiy ca
aeiiiiiaith IE oa ?o aiae?c, noi?ioethaaea iniiai? iieiaeaiiy ?
aeniiaee ?iaioe. Cae?enithaaea ai?iaaaeaeaiiy oa ai?iaaoe?th
iaoa??ae?aaeine?aeaeaiiy a Oe?a?i?. I?aeaiooaaea iaoeia? aeai? aei
ioae?eaoe?? oa aei aenooi?a ia eiioa?aioe?yo, ioi?ieea aeena?oaoe?eio
?iaioo ? aaoi?aoa?ao.

Ai?iiiaeuei? e ?aae?i?ioiieia?/i? aeine?aeaeaiiy aeeiiai? a eaai?aoi???
a?eiai? aiaeie?eiieia?? ? ?aae?i?cioiii?e eaai?aoi??? Oe?a?inueeiai IAe?
ioi?iie caei?ia’y ae?oae ? i?aee?oe?a (i. Oa?e?a).

Ai?iaaoe?y ?iaioe. ?acoeueoaoe aeine?aeaeaiiy aeieeaaeai? oa iaaiai?aii
ia can?aeaii? Oa?e?anueeiai iaoeiaiai iaaee/iiai oiaa?enoaa
aiaeie?eiieia?a (1997); I?aeia?iaeiiio iaaee/iiio eiia?an? nooaeaio?a
? iieiaeeo a/aieo (Oa?iii?eue, 1998); iaoeiai-i?aeoe/ieo
eiioa?aioe?yo “Aeooaeuei? i?iaeaie ioi?iie caei?ia’y ae?oae oe?eueiiai
a?eo i i?aee?oe?a» (Oa?e?a, 1997) ? “Aeooaeuei? aniaeoe aiaeie?eiieo
caoai?thaaiue” (Oa?e?a, 1998); i?aenoieiaeo eiioa?aioe?yo iieiaeeo
a/aieo Oe?IAe? ioi?iie caei?ia’y ae?oae ? i?aee?oe?a (Oa?e?a, 1996,
1998).

Ioae?eaoe?? ?acoeueoao?a aeine?aeaeaiiy. Ii oai? aeena?oaoe??
iioae?eiaaii 11 ae?oeiaaieo ?ia?o o a?o/eciyieo aeo?iaeao ? ca??ieeao, c
ieo 5 noaoae (iaeia naiino?eia) ? 4 oac. Io?eiaii Aea?aeiaoaio Oe?a?ie.
Iaoa??aee aeena?oaoe?? aa?eoee a iaoiaee/i? ?aeiiaiaeaoe??.

Ianya i no?oeoo?a ?iaioe. Aeena?oaoe?y neeaaea?oueny c aaaaeaiiy,
iaeyaeo e?oa?aoo?e, ?icae?eo, ui oa?aeoa?eco? iaoa??ae ? iaoiaee
aeine?aeaeaiiy, 5 aeaa aeanieo aeine?aeaeaiue, iaaiai?aiiy io?eiaieo
?acoeueoao?a, aeniiae?a ? i?aeoe/ieo ?aeiiaiaeaoe?e. ?iaioa aeeeaaeaia
ia 171 noi??ieao iaoeiiieniiai oaenoo, i?noeoue 19 oaaeeoeue ? 37
?enoie?a. Nienie aeei?enoaii? e?oa?aoo?e neeaaea?oueny c 319 aeaea?ae, o
oiio /ene? 157 a?o/eciyieo ? 162 ca?oa?aeieo, ui neeaaeathoue 32
noi??iee.

CIINO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy

Aeey ?aae?caoe?? iinoaaeaieo caaaeaiue i?iaaaeaia eiiieaenia
ee?i?ei-eaai?aoi?ia ianoaaeaiiy 343 oeii/ee?a ? oeiioe?a 10-17 ?ie?a, o
oiio /ene? 141 caei?iaeo c ii?iaeueiei o?ce/iei ? noaoaaei ?icaeoeii ?
202 oai?eo ?c ??ciei nooiaiai CN?.

Ee?i?/ia ianoaaeaiiy ia?aaeaa/aei ioe?ieo o?ce/iiai ?icaeoeo ca aeaieie
e?i?eieo ae?aa?ai (Ei?ai?a e niiaaao., 1995), oeio noaoo?e ? ??aiy
noaoaaiai ?icaeoeo (Aeai/aiei e niiaaao., 1978; Ie?oiaa e niiaaao.,
1996). Noaae?y noaoaaiai aeic??aaiiy aecia/aeany ca eeaneo?eaoe??th
Tanner J. (1966). Nooi?iue cao?eiee noaoaaiai ?icaeoeo ioe?ithaaee ca
aeao?oeeoii noaoaaiai aeic??aaiiy, oiaoi ??cieoe? i?ae ianii?oiei a?eii
? aeinyaiooei ??aiai noaoaaiai aeic??aaiiy (Eaaaiaoeue, 1991; Eaa/oe ,
1992).

Aeine?aeaeaiiy ai?iiiaeueiiai noaoono aeeth/aei aecia/aiiy ??aiy
iaeaoii?io (I) oethi?iiao?e/iei iaoiaeii (Coaeia, 1982) o aeaio
ii?oe?yo na/?: I (I1) — ?c 8 aei 20 aiaeei ? 2 (I2) — ?c 20 aei 8
aiaeei. Aeey aea/aiiy oee?eaaeiaiiiai (aeiaiaiai) ?eoio aene?aoe??
ai?iiio ia aoaiao noaoaaiai aeic??aaiiy e i?ioyaii ?ieo aoa i?iaaaeaiee
aiae?c ni?aa?aeiioaiiy ??aiy I o 2 ? I ii?oe?yo na/? (E-2/I).
?acoeueoaoe aeine?aeaeaiiy ai?noo ai?o?ca?iiai ai?iiio ioe?ithaaeeny o
caeaaeiino? a?ae ianii?oiiai a?eo, a?ieia?/ii? c??eino? iaoe??ioa,
iniaeeainoae ooieoe?iiaeueii? aeoeaiino? ai?o?ca i?ioyaii ?ieo.

Ai?no oanoinoa?iio (Tc), ano?aae?ieo (A2) o e?ia? aecia/aee
?aae?i?ioiieia?/iei iaoiaeii ?c aeei?enoaiiyi eiia?oe?eieo iaai??a AII
A?ei?on?, aiiaaeio?iiieo ai?iii?a (ethoa?i?coth/iai — EA ?
oie?eoeinoeioethth/iai — ONA) — ?ioiioa?iaioiei iaoiaeii, ?c
aeei?enoaiiyi noaiaea?oieo iaai??a eiioea?io «O. Oiooiai-Ea ?io». O
na/? eiei?eiao?e/iei iaoiaeii (Eiea, Eaiuoieeia, 1982) aea/aee ??aaiue
aeiaiai? aene?aoe?? 17-eaoinoa?i?ae?a (17-EN). Io?eiai? ?acoeueoaoe
ioe?ithaaeeny c o?aooaaiiyi a?eiaeo ii?iaoea?a, ?ic?iaeaieo o
eaai?aoi??? a?eiai? aiaeie?eiieia?? ? ?aae?i?cioiii?e eaai?aoi???
Oe?IAe? ICAeI.

Aeey oai?eo ?c ia?aeiii aenieei ai?noii ai?o?ca?iiai ai?iiio a na/?
?ic?iaeaiee ? ai?iaiaaiee iaiaaeeeaiaioiciee iaoiae e?eoaaiiy.

Iaoiaeii aeiaaeeiaeo aea??ie noi?iiaaii aea? a?oie oai?eo.

I a?oio neeaee 27 oeiioe?a 14-17 ?ie?a, ?c CN? I-III nooiaiy oa ??aiai
I, yeee ia?aaeuoaaa a?eiao naciiio ii?io, ui io?eiaee eo?n
ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithaaeueii? oa?ai??
(Aeai/aiei e ni?aaao., 1978) o cae/aeieo oiiaao noaoe?iia?o.

II a?oio neeaee 25 oeiioe?a 14-17 ?ie?a, ?c CN? I-III nooiaiy c
iiae?aieie ci?iaie o ai?no? iaeaoii?io ? ai?iiiaeueiiio noaoon?, ye?
i?ioyaii aeaio oeaei?a o in?iiuei-ceiiaee ia??iae iaea?aeoaaee eo?n
ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithaaeueii? oa?ai?? ia oe?
ci?iaiiai na?oeiaiai ?aaeeio: 8 aiaeei — oai?yaa ? 16 aiaeei — na?oei.
Aeey noai?aiiy ina?oeaiino? a iaeaoao 150-200 ee canoiniaoaaeeny
noaeueia? na?oeeueieee EIAe-4o-20-001 ?c ethi?ianoeaioieie eaiiaie
aeaiiiai na?oea, ii niaeo?o aei?ii?ithaaiiy iaaeeaeai? aei niaeo?o
aeaiiiai na?oea, ?c ia?aaaaeaiiyi o neiuei-o?ieaoia?e ? aeiaoi-caeai?e
eiai /anoei?.

Ooieoe?iiaeueio aeoeai?noue ai?o?ca a i?ioean? e?eoaaiiy ioe?ithaaee ca
ci?iith aaee/eie aene?aoe?? iaeaoii?io ?c na/ath. Aene?aoe?y ai?iiio
aea/aeany a aeeiai?oe?: i?e iaaeoiaeaeaii?, ia 1 aeiao, 7 aeiao ? ii
cae?i/aii? na?oeioa?ai?? (ia 14 aeiao).

Aoaeoeai?noue i?iaaaeaii? oa?ai?? ioe?ithaaee ca aeeiai?eith noaoaaiai ?
o?ce/iiai ?icaeoeo, ci?iaie o ai?iiiaeueiiio noaoon? i?aee?oe?a i?e
aeienoaaii?, /a?ac 6 ? 12 i?nyoe?a. Ciaioaiiy nooiaiy CN? aai
aeinyaiaiiy ??aiy noaoaaiai ?icaeoeo, ui a?aeiia?aea? ianii?oiiio a?eo,
?icoe?ithaaeiny ye iiceoeaia aeeiai?ea.

Noaoenoe/ia ii?aoethaaiiy io?eiaieo aeaieo aoei i?iaaaeaia ca
aeiiiiiaith iaeao?a i?ia?ai “Fox pro” ? «STATGRAPHICS» ia IE IBM PC ?c
aeei?enoaiiyi ia?aiao?e/ieo ? iaia?aiao?e/ieo iaoiae?a, ?acoeueoao?a
ei?aeyoe?eiiai aiae?co. Aeey aecia/aiiy aeinoia??iino? ?icoiaeaeaiue
iieaciee?a aeaio a?oi canoiniaoaaeeny ia?aiao?e/iee t-e?eoa??e
Nouethaeaioa (Pt) ? iaia?aiao?e/iee e?eoa??e U (Pu) –
A?eeieniia-Iaia-O?oi? (Aoaea?, 1987). Aeinoia??i?noue eiao?oe??io?a
ei?aeyoe?? (r) ioe?ithaaeany ii E.Caen (1976).

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy

O ca’yceo c oei, ui aeioaia? caeeoa?oueny aeeneooaaaeueiei ieoaiiy i?i
?nioaaiiy oee?eaaeieo ?eoi?a i?iaeoeoe?? I o ethaeeie, i?iaaaeaia
aea/aiiy aene?aoe?? ai?o?ca?iiai ai?iiio o 94 caei?iaeo oeiioe?a 14-17
?ie?a i?ioyaii ?ieo, e??i e?oiueiai ia??iaeo.

Aiae?c io?eiaieo ?acoeueoao?a aeicaieea anoaiiaeoe ae?aaeai? ci?ie
ooieoe?iiaeueii? aeoeaiino? ai?o?ca a ??ci? i?nyoe? ?ieo (oaae.1).
Iaeiaioee ??aaiue I aoa aecia/aiee a in?ii?e ia??iae: a?i neeaa o
na?aaeiueiio 62.724.13iiieue/aeia. O a?oaei? ? n?/i? ca?a?no?iaaia
aeinoia??ia ca?eueoaiiy ai?noo ai?iiio a aeiaia?e na/? o ii??aiyii? c
iiia?aaei?ie i?nyoeyie (Pu<0.05). C ethoiai i?nyoey a?aecia/aia cieaeaiiy ??aiy aene?aoe?? ai?o?ca?iiai ai?iiio. Ca ia??iae ?c ethoiai ii o?aaaiue na?aaei?e ??aaiue I o aeiaia?e na/? a??ia?aeii ia ci?ithaaany ? neeaa o na?aaeiueiio 78.16.61iiieue/aeia. Oaaeeoey 1 ??/iee ?eoi aene?aoe?? iaeaoii?io ? ?ici??e E-2/1 o caei?iaeo oeiioe?a ? oeiioe?a ?c CN? ( Mm) A?oia ianoaaeaieo I?nyoeue n caei?ia? i?aee?oee n I?aee?oee ?c CN?I, iiieueaeiaE-2/1 M, iiieueaeia K-2/1 aa?anaiue 8 60.88 7.14 1.34 0.28 14 77.01 8.93 * 1.03 0.08 * aeiaoaiue 9 62.87 4.32 1.10 0.03 13 69.38 8.16* 0.99 0.04 eenoiiaae 8 65.50 10.88 1.21 0.22 9 77.15 13.17 * 0.98 0.02 * a?oaeaiue 12 91.85 13.88 0.65 0.15 15 71.63 12.28 * 0.95 0.09 * n?/aiue 19 95.25 3.99 0.77 0.08 34 95.53 9.31 1.02 0.08 * ethoee 18 79.06 7.86 0.76 0.20 33 62.58 6.17 * 1.12 0.08 * aa?acaiue 18 72.14 6.65 1.39 0.41 29 49.23 4.34 * 0.88 0.07 * ea?oaiue 9 90.07 15.86 1.32 0.17 29 62.47 5.57 * 0.94 0.15 * o?aaaiue 7 75.93 16.93 1.35 0.25 16 68.30 9.64 0.97 0.05 * I?ei?oea. *- Pu < 0.05, a??ia?aei?noue a?aei?iiino? ii a?aeiioaiith aei eiio?ieth. I?e aea/aii? aeiaiaiai ?eoio i?iaeoeoe?? I ca ?ici??ii eiao?oe??ioa E-2/I anoaiiaeaii, ui ia?aaaaeaiiy aene?aoe?? ai?iiio a i?/i? /ane ca?a?no?iaaii eeoa a 31.574.37% aeiaaee?a, a?eueo?noue ?c yeeo i?eiaaeaei ia in?ii?e ? aaniyiee ia??iaee, eiee E-2/I ia?aaeuoaaa 1.0 (oaae. 1). O ceiiaee ia??iae (a?oaeaiue - ethoee), iaaiaee, a?aecia/aiee a?eueo aenieee ??aaiue I o aeaii?e ii?oe?? na/?, i?ae o i?/iee. Aeyaeai? iniaeeaino? a oa?aeoa?? aene?aoe?? ai?iiio i?ioyaii aeiae ca?aathoueny c ?acoeueoaoaie, io?eiaieie a oiae? aea/aiiy oee?eaaeiiai ?eoio i?iaeoeoe?? I o aei?ineeo, iiaeaieie a ?iaio? M.A. Hofman et al. (1986), ? na?ae/aoue i?i oa, ui iineeaiiy a?ineioaco ai?iiio a i?/iee /an iaea?eueo oa?aeoa?ia a ia??iaee aeiaaiai na?oeiaiai aeiy. A?aoiaoth/e ?nioaaiiy oee?eaioaeueiiai ?eoio aene?aoe?? iaeaoii?io o caei?iaeo i?aee?oe?a, aea/aiiy ooieoe?iiaeueii? aeoeaiino? ai?o?ca a i?ioean? noaoaaiai aeic??aaiiy /ieia?/iai i?aai?cio i?iaaaeaii a ethoiio i?nyoe?, eiee ??aaiue ai?noo ai?iiio a aeiaia?e na/? iaea?eueo aeecueeee aei na?aaeiuei??/iiai cia/aiiy. Aeine?aeaeaiiy ??aiy iaeaoii?io a 35 caei?iaeo oeii/ee?a ?c ??ciei nooiaiai a?ieia?/ii? c??eino? ? 6 /ieia?e?a aeyaeei ci?io ai?noo I a aeiaia?e na/? ia aoaiao noaoaaiai ?icaeoeo. Anoaiiaeaii, ui aeey oeii/ee?a, ye? ciaoiaeyoueny ia I-II noaae?yo noaoaaiai ?icaeoeo ii Tanner, oa?aeoa?i? a??ia?aeii a?eueo iecuee? cia/aiiy ??aiy I a na/? (ia I noaae?? - 47.752.97iiieue/aeia ? ia II - 43.534.03 iiieue/aeia), i?ae o i?aee?oe?a ?c a?eueo aenieei ??aiai noaoaaiai ?icaeoeo (ia III - 62.446.42 iiieue/aeia, Pu<0.01 ? ia IV - 89.9113.96 iiieue/aeia, Pu<0.01) ? o caei?iaeo /ieia?e?a (151.9831.6iiieue/aeia, Pu<0.05). Aiae?c aene?aoe?? I i?ioyaii aeiae ia aoaiao noaoaaiai aeic??aaiiy a caei?iaeo oeii/ee?a aeicaieea anoaiiaeoe, ui iiyaa aoi?eiieo noaoaaeo iciae o /ieia?/iio i?aai?ci? noi?iaiaeaeoaaeany ciaioaiiyi ieoiii? aaae ai?noo ai?iiio a i?/i? /ane, i?i ui na?ae/eei cieaeaiiy ?ici??o eiao?oe??ioa E-2/I. Oae, o oeii/ee?a, ui ciaoiaeyoueny ia I noaae?? noaoaaiai ?icaeoeo ii Tanner, ?ici?? E-2/I neeaa 1.510.21, ia II noaae?? noaoaaiai aeic??aaiiy - 0.840.04 (Pu<0.05), ia III- 0.710.09 (Pu<0.01) ? ia IV - 0.67 0.15 (Pu<0.01). I?iaaaeaiiy ei?aeyoe?eiiai aiae?co i?ae ai?noii iaeaoii?io a na/?, ?iaeaenii ianeoe?i?caoe?? (?I), ??aiai noaoaaeo ? aiiaaeio?iiieo ai?iii?a o e?ia? o caei?iaeo ianoaaeaieo ?c ??ciei nooiaiai a?ieia?/ii? c??eino? iieacaei, ui aeey oeii/ee?a ?c noaoaaei ?icaeoeii, ui a?aeiia?aea? I noaae?? ii Tanner, oa?aeoa?i? iiceoeai? ei?aeyoe?? i?ae iaeaoii?iii ? ?I (I-?I - r = 0.95, p<0.05), noaoaaeie ai?iiiaie (I-On - r = 0.71, p<0.05 ? M-E2 - r = 0.75, p<0.05) ? EA ( M-EA - r = 0.46, p<0.05). O i?ioean? noaoaaiai ?icaeoeo a?aecia/aia iiyaa iaaaoeaieo ei?aeyoe?eieo aca?iica'yce?a e?eueeino? iaeaoii?io a na/? c ?I (ia III noaae??: I-?I - r= -0.87, p<0.05 ? IV: I-?I - r = -0.61, p<0.05), ?c ??aiai oanoinoa?iio ? aiiaaeio?iiieie ai?iiiaie o e?ia? (ia II noaae??: I-On - r= -0.84, p<0.01, I-EA - r= -0.69, p<0.05,; ia III noaae??: I-EA - r= -0. 51, p<0.05, I-ONA - r= -0. 41, p<0.05 ? M2-Tc - r= -0.50, p<0.05). I?aaenoaaeai? ?acoeueoaoe na?ae/aoue i?i oa, ui noaoaaa aeic??aaiiy a /ieia?/iio i?aai?ci? noi?iaiaeaeo?oueny ci?iith i?iaeoeoe?? iaeaoii?io, i?ia?anoth/ei ciaioaiiyi ieoiii? aaae aene?aoe?? ai?iiio a i?/i? /ane ? oi?ioaaiiyi iaaaoeaieo ei?aeyoe?eieo aca?iica'yce?a i?ae iaeaoii?iii, ?iaeaenii ianeoe?i?caoe??, oanoinoa?iiii ? aiiaaeio?iiieie ai?iiiaie. I?eiouaiiy i?i i?e/aoi?noue iaeaoii?io aei i?ioeano noaiiaeaiiy ?ai?iaeoeoeaii? ooieoe?? a /ieia?/iio i?aai?ci? ciaeoei nai? i?aeoaa?aeaeaiiy i?e aea/aii? ??aiy ai?o?ca?iiai ai?iiio a na/? o oai?eo ?c cao?eieith noaoaaiai aeic??aaiiy. Na?aae ianoaaeaieo i?aee?oe?a c oiia?eueiaiei noaoaaei aeic??aaiiyi oai??, ui iaee I nooi?iue CN?, neeaee 60.43.4%, II - 33.663.3% ? III - 5.941.7%. Aa?iii?eiee o?ce/iee ?icaeoie anoaiiaeaiee o?eueee a 24.252.8% ianoaaeaieo. O a?eueoino? aeiaaee?a aecia/aeinue eiai iia??oaiiy ca ?aooiie iecueeiai c?inoo (60.893.4%), ??aeoa – iaaeinoa/? (8.911.6%) aai iaaeeeoeo (5.951.9%) iane o?ea. O an?o ianoaaeaieo a?aecia/aia ii?ooaiiy ?aoe?iiaeueieo ni?aa?aeiioaiue iicaeiaaei?o ? iiia?a/ieo ?ici???a o?ea, ui noi?iaiaeaeoaaeiny oi?ioaaiiyi iaoieia?/ieo oi?i ii?oioeio. Oae, o 49.53.5% i?aee?oe?a ?c CN? aecia/aiee ?ioaioeeueiee ? a 37.623.4% - ?ioaioeeueii - ?aiooi?aeiee oeie noaoo?e. Cia/ii ??aeoa cono??/aeeny ?aiooi?aeiee (5.451.6%), a?ii?aeiee (2.481.1%), a?ii?aeii-?aiooi?aeiee (1.490.9%) e ?ioaioeeueii-a?ii?aeiee (3.461.3%) oeie ii?oia?ai. Iacaaaeath/e ia oa, ui a 53.44.9% oeiioe?a ?c CN? caoai?thaaiiy iaei niaaeeiai-eiinoeoooe?iiaeueiee oa?aeoa?, i?aeoe/ii an? i?aee?oee (84.02.0%) iaee oi aai ?ioi noiooii caoai?thaaiiy. Iaea?eueo oa?aeoa?iei ii?ooaiiyi ?c aieo ai?iiiaeueiiai noaoono oai?eo ?c CN? noaei cieaeaiiy ??aiy On a?eueo i?ae o aeaa ?ace (2.710.51iiieue/e; o eiio?ie? - 13.11.3iiieue/e, Pt<0.01 ) ia oe? iii??iiai ca?eueoaiiy ??aiy A2 (0.570.09 iiieue/e; o eiio?ie? - 0.320.09 iiieue/e, Pt<0.05), ui noi?iaiaeaeoaaeiny ciaioaiiyi aaee/eie ni?aa?aeiioaiiy ?oiueiai ai?noo o e?ia? (On/A2 - 27.64.2; o eiio?ie? -96.22.4, Pt<0.001). ??aaiue aiiaaeio?iiieo ai?iii?a o na?aaeiueiio ii a?oi? neeaa aeey EA - 2.940.49iIA/ie ? aeey ONA - 3.870.55 iIA/ie. A?eueo i?ae o iieiaeie oai?eo ai?no aiiaaeio?ii?i?a aoa ieae/a a?eiai? ii?ie (EA - 5.210.38 iIA/ie ? ONA - 4.690.8 iIA/ie), o?ioe ??aeoa ?a?no?oaaeeny ii?iaeuei? cia/aiiy ? eeoa a iiiaeeiieeo aeiaaeeao a?aecia/aia i?aeaeuaiiy ??aiy aiiaaeio?iiieo ai?iii?a o e?ia?. Aeine?aeaeaiiy aeiaiai? aene?aoe?? iaeaoii?io o oeiioe?a ?c CN? aeicaieeei anoaiiaeoe, ui na?aaeiuei??/iee ??aaiue (iaci?) I a na/? o oai?eo a??ia?aeii ieae/ee, i?ae o caei?iaeo iaeiieioe?a (69.032.77 iiieue/aeia ? 81.123.04 iiieue/aeia a?aeiia?aeii, Pt<0.01). Iiae oei, o 35.783.27% oai?eo i?aee?oe?a eiai ai?no ia?aaeuoaaa naciiio a?eiao ii?io. Ni?anoaaeyth/e ??aaiue ai?o?ca?iiai ai?iiio o i?aee?oe?a ?c CN? ? o caei?iaeo oeii/ee?a aecia/aii, ui o oai?eo ?c CN? ?ici?? aeiaiai? aene?aoe?? iaeaoii?io a??ia?aeii aeua, i?ae o caei?iaeo ianoaaeaieo, yei aeinyaee iiae?aiiai ??aiy a noaoaaiio ?icaeoeo (ia I noaae?? ii Tanner: o oai?eo ?c CN? - 60.083.62iiieue/aeia; o eiio?ie? - 47.752.97iiieue/aeia, Pu<0.001 ? ia II noaae?? ii Tanner: o oai?eo ?c CN? - 65.244.56iiieue/aeia; o eiio?ie? - 43.574.03iiieue/aeia, Pu<0.001). Anoaiiaeaii ci?ie e o oa?aeoa?? aeiaiaiai (oee?eaae?aiiiai) ?eoio aene?aoe?? ai?o?ca?iiai ai?iiio, i?i ui na?ae/eoue a?aenooi?noue oa?aeoa?iiai aeey caei?iaeo oeii/ee?a ciaioaiiy i?iaeoeoe?? iaeaoii?io a i?/iee /an o i?ioean? noaoaaiai aeic??aaiiy. Oae, aaee/eie eiao?oe??ioa E-2/I o i?aee?oe?a ?c CN?, ui ciaoiaeyoueny ia I ? II noaae?yo noaoaaiai aeic??aaiiy ii Tanner, a??ia?aeii ia a?ae??ciyeeny i?ae niaith, neeaaoe 1.070.08 ? 0.960.1 a?aeiia?aeii, Pu>0.05.

I?e i?iaaaeaii? ei?aeyoe?eiiai aiae?co o oai?eo ?c CN? aac aoi?eiieo
noaoaaeo iciae ia aeyaeaii iiceoeaieo ei?aeyoe?eieo aca?iica’yce?a ??aiy
iaeaoii?io c? noaoaaeie ? aiiaaeio?iiieie ai?iiiaie, oa?aeoa?ieo aeey
caei?iaeo oeii/ee?a ia ?aii?o aoaiao noaiiaeaiiy ?ai?iaeoeoeaii?
ooieoe??.

Aeine?aeaeaiiy ??aiy ai?o?ca?iiai ai?iiio o i?aee?oe?a ?c CN? i?ioyaii
?ieo iieacaei, ui o ieo ??/iee (oei?eaioaeueiee) ?eoi aeiaiai?
aene?aoe?? I ia? ?yae a?aei?iiinoae o ii??aiyii? c? caei?iaeie
iaeiieioeaie (oaae.1): ??cia aiie?ooaea eieeaaiue aaee/eie
na?aaeiueii?ny/iiai ??aiy iaeaoii?io a in?ii?e ? aaniyiee ia??iae uiaei
iaci?a, ia ca?aa?oueny /an iaea?eueoiai i?aeeiio (ae?ioaca) ? niaaeo
(aaoeoaca) a aene?aoe?? ai?iiio. Iieacaii, ui a oeiioe?a ?c CN?
oee?eaae?aiiee ?eoi aene?aoe?? ai?o?ca?iiai ai?iiio ia caeaaeeoue a?ae
naciio (oaae.1).

Aea/aiiy ai?noo I a caeaaeiino? a?ae nooiaiy CN?, ii?oioeio, ?ai?o
ia?aianaieo ? noiooiio caoai?thaaiue aeicaieeei anoaiiaeoe, ui aaee/eia
ai?noo ai?o?ca?iiai ai?iiio a aeiaia?e na/? i?yii i?iii?oe?eia nooiaith
CN? (o i?aee?oe?a ?c I nooiaiai CN? — 67.513.6iiieue/aeia, ?c II —
70.284.38 iiieue/aeia (Pu1<0.05) ? c III - 77.385.56 iiieue/aeia (Pu2<0.05 ? Pu3<0.01). Iaea?eueo aenieee ??aaiue iaeaoii?io a?aecia/aiee o oai?eo ?c ?ioaioeeueiei (73.43.87 iiieue/aeia) oeiii noaoo?e, o i?aee?oe?a ?c aenieei ?ioaeoe?eiei ?iaeaenii (102.3913.04 iiieue/aeia, Pu<0.001) oa oeiioeia, ye? ?ai?oa ia?aianee cae?eoo /a?aiii-iiceiao o?aaio (86.7612.15iiieue/aeia, Pu<0.001), ?c aooe?ai?aeiei aeeoociei ca?eueoaiiyi ueoiaeaeii? caeice I-II nooiaiy (81.557.22 iiieue/aeia, Pu<0.001), caoai?thaaiiyie na?oeaai-noaeeiii? (85.47.67 iiieue/aeia, Pu<0.001) ? o?aaii? nenoai (81.79.3 iiieue/aeia, Pu<0.001), o ii??aiyii? c oeiioeyie, ye? ia iathoue noiooiio iaoieiai/ieo noai?a (56.264.67 iiieue/aeia). Iiaeai? aeai? i?i oa?aeoa? aene?aoe?? iaeaoii?io a i?aee?oe?a ?c CN? aeicaieeee i?eionoeoe, ui o ?yae? aeiaaee?a aenieee ??aaiue ai?o?ca?iiai ai?iiio iiaea aooe iaeiei ?c iaoiaaiaoe/ieo iaoai?ci?a oi?ioaaiiy oe??? iaoieia??. Oea noaei i?aenoaaith aei canoinoaaiiy a oai?eo ?c ??aiai ai?iiio, yeee ia?aaeuo? naciiio a?eiao ii?io, iaoiaeo e?eoaaiiy, ni?yiiaaiiai ia cieaeaiiy i?iaeoeoe?? iaeaoii?io. I?ae niinoa?aaeaiiyi ciaoiaeeeiny 52 oeiioey 14-17 ?ie?a ?c CN? I-III nooiaiy, o yeeo aeyaeaia i?aeaeuaiiy aene?aoe?? iaeaoii?io. O caeaaeiino? a?ae iaoiaeo e?eoaaiiy noi?iiaaii aea? a?oie oai?eo: I a?oia - 27 oeiioe?a, ui io?eiaee eo?n ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithaaeueii? oa?ai?? o cae/aeieo oiiaao noaoe?iia?o oa II a?oia - 25 oeiioe?a, ui i?ioyaii aeaio oeaei?a o in?iiuei-ceiiaee ia??iae iaea?aeoaaee iiaeiaiee eo?n oa?ai?? ia oe? ci?iaiiai na?oeiaiai ?aaeeio. Ee?i?/ia ianoaaeaiiy i?aee?oe?a ?c CN? oa aenieei ??aiai I iieacaei, ui na?aae ieo /ano?oa, i?ae o oe?eiio ii a?oi? oai?eo ?c CN? cono??/aeeny oeiioe? c ?ioaioeeueiei oeiii noaoo?e (71.156.28% ? 49.53.52% a?aeiia?aeii, p<0.01), ye? ?ai?oa ia?aianee cae?eoo /a?aiii-iiceiao o?aaio (34.626.6% ? 16.171.83% a?aeiia?aeii, p<0.01), no?aaeaeathoue /anoeie ?ani??aoi?ii-a??onieie caoai?thaaiiyie (59.626.8% ? 35.932.73% a?aeiia?aeii, p<0.01), ?c noiooiiie iaoieiai/ieie noaiaie c aieo ?ioeo i?aai?a ? nenoai (94.233.23% ? 84.02.04% a?aeiia?aeii, p<0.01). I?e aeineiaeaeaiii ai?iiiaeueiiai noaoono o i?aee?oe?a aeaii? a?oie oai?eo anoaiiaeaii, ui i?aeaeuaiiy aene?aoe?? I noi?iaiaeaeoaaeiny a?eueo ae?aaeaiei i?eai?/aiiyi i?iaeoeoe?? ONA (2.690.21 iME/ie, Pu<0.05) ? A2 (0.250.08 iiieue/e, Pu<0.05), i?ae o oe?eiio ii a?oi? oeiioeia ?c CN?. Aea/aiiy ??aiy ai?o?ca?iiai ai?iiio a oai?eo II a?oie a aeeiaiioei ciinoa?aaeaiiy aeicaieeei anoaiiaeoe, ui iiae aieeaii i?iaeiaaeaiiy na?oeiaiai aeiy a?aecia/aeiny ciaioaiiy aene?aoe?? I ?c 106.654.67iiieue/aeia aei 77.784.48iiieue/aeia (Pu<0.05) /a?ac aeiao i?ney canoinoaaiiy aeaiiai ?aaeeio ? aei 60.253.8 iiieue/aeia (Pu<0.05) ii cae?i/aii? oa?ai??. Cieaeaiiy ??aiy ai?iiio a?aeaoaaeiny ye aii/? (I2), oae ? aaeaiue (I1) (iae.1). wmetafile8? ??f???5???????? ???????yyy???????????? [—??? ????'yy??? ????'yy??? ??????? ????yyy???? ???????'yy??? ????yyy???? ???????[—???????'yy??? ????yyy???? ???????[—???????'yy??? ????yyy???? ???????V’?????ue???????????-?? ???u?????????"????-???? ???????????????$?†?7—?*d*S7†?7???ue??yyy??????-? ??? yyy???????????$?†?7†?h?—?[?—?*†?7???$?—?*—?[?d[?d*—?* ???U?c???? ???u??????????"????-?????????7†????yyy????????*—? ???*d???†????—????d???o?†????a?—????a?d?? ???†????A?—????A?d????†???? ?—???? ?d???‹?†???? ?—?????d???h?†????[?—????[?d ???u??????????"????-????-????'yy??? ????-????-????yyy???? yyy????V’?????ue?????? ???-???? ??????????????????????$?d*S7†?7—?*d* ???u?????????"????-?????????U?c???????$?†?7†?h?—?[?—?*† ?7???$?—?*—?[?d[?d*—?*???-????-????'yy??? ????-????-??????????? ???????V’?? ???u?????????"????-?????????????????&??yyyy?? ???u?????yyy?"????-????ue??????????-??????????????? ????5???B???(??????????????? ???Ae??Ae????????????????Iae. 1 - Ci?ia aene?aoe?? iaeaoii?io o oai?eo ?c CN? II a?oie ia oe? ci?iaiiai na?oeiaiai ?aaeeio Ciaioaiiy i?iaeoeoe?? I ii?aeioaaeiny c a??ia?aeii a?eueo ae?aaeaiei i?aeaeuaiiyi ai?noo aiiaaeio?iiieo ai?iii?a o e?ia? ? ??aiy aene?aoe?? 17-EN ?c na/ath ii cae?i/aii? eo?no e?eoaaiiy a noaoe?iia??, a ii??aiyii? c i?aee?oeai I a?oie (oaae.2). Oaaeeoea 2 Ai?no aiiaaeio?iiieo, noaoaaeo ai?iiiia a e?iai, ?iaaiue aeiaiai? aene?aoei? 17-EN o oeiioeia ?c CN? a aeeiaiioei niinoa?aaeaiiy (Mm) *an ianoaaeaiiyAeine?aeaeoaai? iieacieeeaeo?aeiii?e aeienoaaii?/a?ac iia?ieo /a?ac ?ie I a?oiaII a?oia I a?oia II a?oia I a?oia II a?oia I a?oia II a?oiaEA, iIA/ieM m3.11 0.322.53 0.153.24 0.734.63* 0.743.46 0.873.18 0.633.87 1.064.27* 0.48Pu>0.05<0.05>0.05>0.05ONA, iIA/ieM

m2.52

0.162.72

0.083.09

0.766.65*

0.483.25

0.583.06

0.533.43*

0.354.70*

0.21Pu>0.05<0.01>0.05<0.05Tc, iiieue/eM m2.42 0.321.90 0.354.05* 1.144.21* 1.044.93* 0.606.28* 1.237.87* 1.0310.52* 1.73Pu>0.05>0.05<0.05<0.05E2, iiieue/eM m0.28 0.110.23 0.060.54* 0.160.33* 0.140.62* 0.140.77* 0.200.50* 0.190.46* 0.17Pu>0.05<0.05>0.05>0.0517-KC, ieiieue/aeiaM

m12.97

0.9112.83

0.6314.80

1.1918.15*

1.1815.86*

1.3417.95*

1.3417.74*

2.1522.16*

0.99Pu>0.05<0.01>0.05<0.05 I?ei?oee: 1. * - aeinoia??i?noue a?aei?iiino? noiniaii aeo?aeieo cia/aiue; 2. Pu - aeinoia??i?noue a?aei?iiino? i?ae I e II a?oiaie ianoaaeaieo. Ianoaaeaiiy i?aee?oe?a ?c CN? /a?ac 6 ? 12 i?nyoe?a aeicaieeei anoaiiaeoe a?eueo aenieo aoaeoeai?noue i?iaaaeaiiai e?eoaaiiy i?e niieo/aii? ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeith/i? oa?ai?? ?c ci?iith na?oeiaiai ?aaeeio. *a?ac 6 i?nyoe?a o I a?oi? oai?eo, ui io?eioaaee oa?ai?th a cae/aeieo oiiaao noaoe?iia?o, eeoa o 3 (11.11%) i?aee?oe?a a?aecia/aia ciaioaiiy nooiaiy CN?, o oie /an ye na?aae oai?eo II a?oie, ye? ciaoiaeeeeny i?ae /an e?eoaaiiy i?e ci?iaiiio na?oeiaiio ?aaeei?, ciaioaiiy nooiaiy CN? ca?a?no?iaaia o 6 (36.0%) ianoaaeaieo. *a?ac ??e a a?oi? o 5 (18.52%) i?aee?oe?a noaoaaee ?icaeoie noaa a?aeiia?aeaoe a?eo e o 4 (14.81%) a?aecia/aia ciaioaiiy nooiaiy CN?, a a II a?oi? o 13 (52.0%) oeiioe?a a?aecia/aia iiceoeaia ee?i?/ia aeeiai?ea, c ieo: o 8 (32.0%) noaoaaee ?icaeoie noaa a?aeiia?aeaoe ianii?oiiio a?eo e o 5 (20.0%) ciaioeany nooi?iue CN?, ui ocaiaeeeiny c? ci?iaie o ai?no? EA, ONA, On ? 17-EN (oaae.2). Iiaeai? aeai? aeicaieeee c?iaeoe aeniiaie, ui ci?ia na?oeiaiai ?aaeeio a in?iiuei-ceiiaee ia??iae aeey oeiioe?a ?c CN? i?e ia?aeiii aenieiio ??ai? aene?aoe?? iaeaoii?io ? iaoiaaiaoe/iei iaoiaeii e?eoaaiiy, ni?yiiaaiei ia ciaioaiiy i?ioeaiiaaeio?iiiiai aieeao ai?o?ca?iiai ai?iiio ? i?aeaeuaiiy ooieoe?iiaeueii? aeoeaiino? a?iio?ca?ii-aiiaaeiiai eiiieaeno. AENIIAEE 1. Noaoaaa aeic??aaiiy /ieia?/iai i?aai?cio noi?iaiaeaeo?oueny ci?iith ??aiy aeiaiai? aene?aoe?? iaeaoii?io ? oa?aeoa?o eiai oee?eaaeiiai ?eoio. 2. Ni?yiiaai?noue oa ?ioaineai?noue ei?aeyoe?eieo aca?iica'yce?a i?ae ai?noii iaeaoii?io, ?ici??ii ciai?oi?o noaoaaeo i?aai?a, ae?aaeai?noth aoi?eiieo noaoaaeo iciae, ??aiai noaoaaeo noa?i?ae?a ? aiiaaeio?iiieo ai?iii?a o e?ia? caeaaeeoue a?ae noaae?? noaoaaiai aeic??aaiiy. 3. ??aaiue aene?aoe?? iaeaoii?io o caei?iaeo oeiioe?a ci?ith?oueny i?ioyaii ?ieo ? aeinyaa? iaeneioio a a?oaei? - n?/i? i?nyoe?. Aeiaiaee ?eoi ?c ia?aaaaeaiiyi aene?aoe?? iaeaoii?io a i?/iee /an ?a?no?o?oueny a i?aee?oe?a a in?ii?e ? aaniyiee ia??iaee. O ceiia? i?nyoe?, iaaiaee, ca?eueoaia aeae?eaiiy iaeaoii?io c 8 aei 20 aiaeeie. 4. O oeiioe?a ?c CN? ai?no iaeaoii?io ia a?aeiia?aea? aeinyaiooiio ieie ??aith a?ieia?/ii? c??eino? ? caeaaeeoue a?ae nooiaiy iaoieia?/iiai i?ioeano, ii?oioeio ? noiooiio caoai?thaaiue. 5. O i?aee?oe?a ?c CN? ci?iaiee oa?aeoa? ei?aeyoe?eiiai aca?iica'yceo i?ae ??aiai iaeaoii?io a na/? e ai?noii oanoinoa?iio, ano?aae?ieo, ethoa?i?coth/iai ? oie?eoeinoeioethth/iai ai?iii?a o e?ia?. 6. ??/iee ?eoi aene?aoe?? iaeaoii?io a oai?eo ?c CN? a?ae??ciy?oueny aaee/eiith iaci?o, aiie?ooaeith eieeaaiiy na?aaeiueii?ny/ieo cia/aiue, /anii ianoaiiy ae?ioace ? aaoeoace a ii??aiyii? ?c caei?iaeie iaeiieioeaie. 7. Eiiieaenia canoinoaaiiy ci?ie na?oeiaiai ?aaeeio a in?iiuei-ceiiaee ia??iae, ca ?aooiie iiaeiaaeaiiy na?oeiaiai aeiy aei 16 aiaeei, oa eo?no ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithth/i? oa?ai?? o oeiioe?a ?c CN? i?e ??ai? iaeaoii?io a na/?, ui ia?aaeuo? a?eiao naciiio ii?io, i?ecaiaeeoue aei ciaioaiiy aene?aoe?? ai?o?ca?iiai ai?iiio, i?aeaeuaiiy ai?noo noaoaaeo, aiiaaeio?iiieo ai?iii?a o e?ia? ? aeiaiai? aene?aoe?? 17-eaoinoa?i?ae?a ?c na/ath, a oaeiae aei ci?ie oa?aeoa?o ei?aeyoe?eieo aca?iica'yce?a aaee/eie aene?aoe?? iaeaoii?io c ??aiai aeine?aeaeoaaieo aiiaaeio?iiieo ai?iii?a. 8. I?iaaaeaiiy ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithth/i? oa?ai?? ia oe? ci?iaiiai na?oeiaiai ?aaeeio a in?iiuei-ceiiaee ia??iae aeicaieeei i?aeaeueoe aoaeoeai?noue e?eoaaiiy c 33.3% aei 52% /a?ac ??e a?ae ii/aoeo e?eoaaiiy. I?AEOE*I? ?AEIIAIAeAOe?? 1. I?e aea/aii? ??aiy iaeaoii?io c iaoith ae?aaiinoeee a oeii/ee?a ? oeiioe?a iaiao?aeii a?aoiaoaaoe ia o?eueee ianii?oiee a?e, nooi?iue a?ieia?/ii? c??eino?, aea ? i?nyoeue (nacii), eiee i?iaiaeeoueny aeine?aeaeaiiy. 2. Aecia/aiiy aenieeo ??ai?a iaeaoii?io ia ?aii?o aoaiao noaoaaiai aeic??aaiiy a oeii/ee?a aa?oi ?icoe?ithaaoe ye /eiiee ?eceeo ?icaeoeo cao?eiee noaoaaiai aeic??aaiiy. 3. O oeiioe?a ?c ??aiai iaeaoii?io, ui ia?aaeuo? naciiio a?eiao ii?io, aeioe?eueii a in?iiuei-ceiiaee ia??iae i?ioyaii aeaio oeaei?a canoinoaaiiy eiiieaeno ianiaoeeo?/ii? noeioethth/i? ? caaaeueiici?oeithth/i? oa?ai?? ia oe? iiaeiaaeaiiai aei 16 aiaeei na?oeiaiai aeiy. Aeey noai?aiiy o iaeaoao ina?oeaiino? 150-200 ee ?aeiiaiaeiaaia canoinoaaiiy noaeueiaeo na?oeeueiee?a EIAe-4o-20-001 ?c ethi?ianoeaioieie eaiiaie aeaiiiai na?oea, ye? ii niaeo?o aei?ii?ithaaiiy iaaeeaeathoueny aei niaeo?o aeaiiiai na?oea ?c ia?aaaaeaiiyi o neiuei-o?ieaoia?e ? aeiaoi-caeai?e eiai /anoei?. NIENIE IOAE?EAOe?E II OAI? AeENA?OAOe?? 1.Cao?eiea noaoaaiai ?icaeoeo oeiioeia oa ?o eieoaaiiy / I.I.Ie?oiaa, E.I.Eaa/oe, A.A.Aieiai?iaeueei, E.Ae.Iieioiia, A.A.Co?aa, N.I.Oo?/eia // Iaaeiao?iy, aeooa?noai i aiiaeieiaiy,1997, ? 5. - C. 84-87. 2.Ieaoiaa A.E., Oo?/eia N.E. Ooieoeeiiaeueiay aeoeaiinoue yieoeca iiae?inoeia, nooi/iua e aiaeiaua ?eoiu // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu. - 1998. - Aui.20. - N. 95-97. 3.Yene?aoeey iaeaoiieia o caei?iauo iaeue/eeia-iiae?inoeia a i?ioeanna iieiaiai nic?aaaiey / A.E. Ieaoiaa, N.E. Oo?/eia, I.I. Oeaeiye, N.O.*a?aaaoiaa // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu. - 1998. - Aui.23. - N. 89-93. 4. Oo?/eia N.E. Iiaua iaoiaaiaoe/aneea iiaeoiaeu e oa?aiee iaeue/eeia-iiae?inoeia n caaea?aeeie iieiaiai ?acaeoey // Aiaeie?eiieiaiy. -1998. - O3, ?2. - N. 163-169. 5. Ie?oiaa I.?., Oo?/eia N.I., Aieiai?iaeueei A.A. ?ieue iaeaoiiiio o oi?ioaaiii cao?eiee noaoaaiai ?icaeoeo oeiioeia // Iaaeiao?iy, aeooa?noai i aiiaeieiaiy,1999, ? 2. - C. 35-36. 6. Iaoaio Oe?aeiu ? 97073955. IIE 6A61N5/16. Niinia eieoaaiiy cao?eiee noaoaaiai ?icaeoeo o oeii/eeia-iiaeeioeia / Ieaoiaa A.E., Oo?/eia N.E. - ? 25612; Cayae. 12.11.97; Iioae. 23.09.98. - 2 c. 7. Cao?eiea noaoaaiai ?icaeoeo oeiioe?a oa ?o ?aaa?e?oaoe?y / I.?.Ie?oiaa, E.I.Eaa/oe, E.Ae.I?e?o?ia, A.A.Co?aa, N.I.Oo?/eia, A.I.Eieiii?oeue, A.I.A?aociaa, I.A. AEaeaiiaa, I.I.Iiiia, I.A.Oeyoiaa, A.A. Aieiai?iaeueei, I.Ae.Naaai: Iaoiae. ?ae. - Oa?e?a, 1996. - 17 n. 8. Ieaoiaa A.E., Oo?/eia N.E. Naciiiua eieaaaiey niaea?aeaiey iaeaoiieia o iaeue/eeia-iiae?inoeia n caaea?aeeie iieiaiai ?acaeoey // Aeo. i?iae. aeao. e iiae?. yiaeie?eiie: Oac. aeiee. iao/.-i?aeo. eiio. (Oa?ueeia, 6-7 aeae. 1995 a.). - Oa?ueeia, 1995. - N. 57. 9.Oo?/eia N.E. Niaea?aeaiea iaeaoiieia o iaeue/eeia-iiae?inoeia n ?acee/iuie oi?iaie ia?ooaiey iieiaiai nic?aaaiey // I I?aeia?iaeiee iaae.eiia?an nooaeaio?a ? iieiaeeo a/aieo: Oace aeii.-Oa?iiiieue, 1997. -N.73-74. 10. Ieaoiaa A.E., THoa?iaa A.A., Oo?/eia N.E. Yieoec e iieiaia nic?aaaiea // Iaoe.- i?aeo.eiio. Aeooaeuei? i?iaeaie ioi?iie caei?ia’y ae?oae oe?eueiiai a?eo ? i?aee?oeia": Oace aeii. -Oa?ueeia, 1997. - N.58-59. AIIOAOe?ss Oo?/eia N.?. I?i o/anoue iaeaoii?io o noaoaaiio aeic??aaii? ? oi?ioaaii? eiai cao?eiee o oeiioe?a-i?aee?oe?a. - ?oeiien Aeena?oaoe?y ia caeiaoooy a/aiiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca oaoii 14.01.14 - aiaeie?eiieia?y. - ?inoeooo aiaeie?eiieia?? oa iai?io ?a/iaei ?i. A.I. Eii?na?aiea AII Oe?a?ie, Ee?a,1999. Aeena?oaoe?y i?enay/aia aea/aiith ?ie? iaeaoii?io a iaoai?ciao noaiiaeaiiy /ieia?/i? noaoaai? nenoaie ? oi?ioaaiiy cao?eiee noaoaaiai aeic??aaiiy o oeiioe?a. Anoaiiaeaii, ui noaoaaa aeic??aaiiy noi?iaiaeaeo?oueny ci?iith ??aiy aeiaiai? aene?aoe?? iaeaoii?io ? oa?aeoa?o eiai oee?eaaeiiai ?eoio. Iieacaii ?nioaaiiy ??/iiai ?eoio i?iaeoeoe?? iaeaoii?io ? caeaaei?noue oa?aeoa?o aeiaiaiai ?eoio aene?aoe?? ai?iiio a?ae naciio ?ieo. O i?aee?oe?a ?c CN? ai?no iaeaoii?io ia a?aeiia?aea? aeinyaiooiio ieie ??aith a?ieia?/ii? c??eino? ? caeaaeeoue a?ae nooiaiy iaoieia?/iiai i?ioeano, ii?oioeio, noiooiio caoai?thaaiue. ??/iee ?eoi aene?aoe?? ai?iiio o oai?eo ?c CN? ia? ?yae a?aei?iiinoae o ii??aiyii? c? caei?iaeie ia?aaanieeaie. Cai?iiiiiaaiee i?eioeeiiai iiaee iaoiae e?eoaaiiy CN?, caniiaaiee ia i?eai?/oaaii? i?iaeoeoe?? iaeaoii?io. Eeth/ia? neiaa: iaeaoii?i, oee?eaaeiee ?eoi, noaoaaa aeic??aaiiy, cao?eiea noaoaaiai ?icaeoeo, e?eoaaiiy cao?eiee noaoaaiai ?icaeoeo. Oo?/eia N.E. Ia o/anoee iaeaoiieia a iieiaii nic?aaaiee e oi?ie?iaaiee aai caaea?aeee o iaeue/eeia-iiae?inoeia. - ?oeiienue Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.14 - yiaeie?eiieiaey. - Einoeooo yiaeie?eiieiaee e iaiaia aauanoa ei. A.I. Eiienna?aiei AII Oe?aeiu, Eeaa, 1999. Aeenna?oaoeey iinayuaia eco/aieth ?iee iaeaoiieia a iaoaieciao noaiiaeaiey ioaeneie iieiaie nenoaiu e oi?ie?iaaiey caaea?aeee iieiaiai nic?aaaiey o iaeue/eeia-iiae?inoeia. Ia iniiaaiee enneaaeiaaiey niaea?aeaiey iaeaoiieia a ii/a o 141 caei?iaiai iaeue/eea 10-17 eao n aa?iiie/iui oece/aneei e niioaaonoaothuei ianii?oiiio aic?anoo iieiaui ?acaeoeai, aiaeeca acaeiiioiioaiee yieoeca?iiai ai?iiia n iieiauie noa?ieaeaie e aiiaaeio?iiiuie ai?iiiaie ia yoaiao iieiaiai nic?aaaiey aeieacaia i?e/anoiinoue iaeaoiieia e iaoaieciai, eiio?iee?othuei noaiiaeaiea ioaeneie ?ai?iaeoeoeaiie nenoaiu. Onoaiiaeaii nouanoaiaaiea aic?anoiie aeeiaieee niaea?aeaiey iaeaoiieia n aeinoiaa?ii aieaa ieceei o?iaiai ai?iiia ia ?aiieo yoaiao iieiaiai nic?aaaiey. Auyaeaia caaeneiinoue iai?aaeaiiinoe e eioaineaiinoe ei??aeyoeeiiiuo acaeiinaycae iaaeaeo aaee/eiie niaea?aeaiey iaeaoiieia a ii/a e ?acia?ii ia?oaeiuo iieiauo i?aaiia, noaiaiueth au?aaeaiiinoe aoi?e/iuo iieiauo i?eciaeia, o?iaiai iieiauo noa?ieaeia e aiiaaeio?iiiuo ai?iiiia a e?iae io noaaeee iieiaiai nic?aaaiey ii Oanner. Oaeaea ii?aaeaeaii, /oi noaiiaeaiea ?ai?iaeoeoeaiie ooieoeee o iaeue/eeia nii?iaiaeaeaaony eciaiaieai oa?aeoa?a nooi/iiai ?eoia iaeaoiieia, ca n/ao i?ia?anne?othuaai oiaiueoaiey yene?aoeee ai?iiia a ii/iia a?aiy. Aeieacaii nouanoaiaaiea aiaeiaiai ?eoia i?iaeoeoeee iaeaoiieia n ae?ioacie (iaeneiaeueiuie cia/aieyie), niioaaonoaothuae aeaeaa?th-yiaa?th ianyoeai. Iieacaii, /oi oa?aeoa? nooi/iiai ?eoia yene?aoeee yieoeca?iiai ai?iiia caaeneo io naciia aiaea: a inaiiee e aanaiiee ia?eiaeu i?aiaeaaeaao yene?aoeey iaeaoiieia a ii/iia a?aiy, a ceiiea ianyoeu, iai?ioea, oaaee/aii auaeaeaiea ai?iiia n 8 aei 20 /ania. Ianeaaeiaaiea 202 iaeue/eeia-iiae?inoeia 14-17 eao n caaea?aeeie iieiaiai ?acaeoey (CI?) I-III noaiaie iicaieeei onoaiiaeoue, /oi o aieueiuo iiae?inoeia aaee/eia niaea?aeaiey iaeaoiieia a nooi/iie ii/a ia niioaaonoaoao ie eo ianii?oiiio aic?anoo, ie aeinoeaiooiio o?iaith aeieiae/aneie c?aeinoe: niaea?aeaiea ai?iiia a nooi/iie ii/a o aieueiuo n caiaaeeaiiui ioaa?oaoii ai anao aic?anoiuo a?oiiao ieaea, /ai o caei?iauo naa?noieeia, e aeinoiaa?ii auoa, /ai o caei?iauo iaeue/eeia, aeinoeaoeo noiaeiiai o?iaiy a iieiaii ?acaeoee. Oaeaea ii?aaeaeaiu eciaiaiey a oa?aeoa?a nooi/iiai ?eoia yene?aoeee eco/aaiiai yieoeca?iiai ai?iiia, i /ai naeaeaoaeuenoaoao ionoonoaea oa?aeoa?iiai aeey caei?iauo iaeue/eeia oiaiueoaiey i?iaeoeoeee iaeaoiieia a ii/iia a?aiy a i?ioeanna iieiaiai nic?aaaiey. Auyaeaii, /oi a ioee/ea io caei?iauo iaeue/eeia, iaoiaeyueony ia ?aiieo yoaiao noaiiaeaiey ?ai?iaeoeoeaiie ooieoeee, aeey aieueiuo n ionoonoaothueie aoi?e/iuie iieiauie i?eciaeaie ia oa?aeoa?iu iieiaeeoaeueiua ei??aeyoeeiiiua acaeiinayce iaeaoiieia n iieiauie e aiiaaeio?iiiuie ai?iiiaie. Onoaiiaeaii, /oi aaee/eia nooi/iie yene?aoeee iaeaoiieia i?yii i?iii?oeeiiaeueia noaiaie caaea?aeee iieiaiai ?acaeoey, a oaeaea caaeneo io ii?oioeia e oa?aeoa?a niioonoaothueo iaoieiae/aneeo ninoiyiee e caaieaaaiee. Iieacaii, /oi aiaeiaie ?eoi yene?aoeee yieoeca?iiai ai?iiia o aieueiuo n CI? eiaao ?yae ioee/ee a n?aaiaiee ni caei?iauie naa?noieeaie. Eiathony ?acee/ey a aaee/eia iaci?a (n?aaeiaaiaeiaie o?iaaiue), aiieeooaea eieaaaiee n?aaeiaiany/iuo cia/aiee, a?aiaiai ianooieaiey ae?ioacu e aaoeoacu a n?aaiaiee ni caei?iauie naa?noieeaie. Oae, o caei?iauo iiae?inoeia au?aaeaiiia oaaee/aiea nooi/iie yene?aoeee iaeaoiieia niioaaonoaoao aeaeaa?th - yiaa?th, a o iiae?inoeia n CI? niauaii ia yiaa?ue. Iaeiaiueoee o?iaaiue (aaoeoaca) yieoeca?iiai ai?iiia o aieueiuo ca?aaeno?e?iaai a aanaiiea ianyoeu, a o caei?iauo - a inaiiea. Oaeei ia?acii, iieo/aiiua a oiaea auiieiaiey ?aaiou ?acoeueoaou naeaeaoaeuenoaotho i oii, /oi i?e eco/aiee o?iaiy iaeaoiieia n aeeaaiinoe/aneie oeaeueth o iaeue/eeia e iaeue/eeia-iiae?inoeia iaiaoiaeeii o/eouaaoue ia oieueei ianii?oiue aic?ano, noaiaiue aeieiae/aneie c?aeinoe, ii e ianyoe (nacii), eiaaea i?iaiaeeony enneaaeiaaiea. Ii?aaeaeaiea aea aunieeo cia/aiee iaeaoiieia ia ?aiieo yoaiao iieiaiai nic?aaaiey neaaeoao ?anoeaieaaoue eae oaeoi? ?enea ?acaeoey caaea?aeee iieiaiai ?acaeoey. Auyaeaiiua iniaaiiinoe yene?aoeee yieoeca?iiai ai?iiia o aieueiuo n caiaaeeaiiui ioaa?oaoii iicaieeee oai?aoe/anee iainiiaaoue i?eiaiaiea o iaeue/eeia-iiae?inoeia n CI?, i?e o?iaia iaeaoiieia a ii/a, i?aauoathuai naciiioth aic?anoioth ii?io, iaoiaea ea/aiey, iai?aaeaiiiai ia iiaeaaeaiea i?iaeoeoeee ai?iiia. Aeey aeaiiiai eiioeiaaioa aieueiuo oeaeaniia?acii a inaiia-ceiiee ia?eiae ia i?ioyaeaiee aeaoo iaaeaeue i?iaaaeaiea eiiieaena ianiaoeeoe/aneie noeioee?othuae e iauaoe?aieythuae oa?aiee ia oiia i?iaeeaiiiai aei 16 /ania naaoiaiai aeiy. Aeey nicaeaiey inaauaiiinoe a iaeaoao 150-200 ee ?aeiiaiaeiaaii i?eiaiaiea iioiei/iuo naaoeeueieeia EIAe-4o-20-001 n ethieianoeaioiuie eaiiaie aeiaaiiai naaoa, ii niaeo?o eceo/aiey i?eaeeaeathueony e niaeo?o aeiaaiiai naaoa n i?aiaeaaeaieai a neia-oeieaoiaie e aeaeoi-caeaiie aai /anoe. Ni/aoaiea eciaiaiey naaoiaiai ?aaeeia a inaiia-ceiiee ia?eiae e eo?na ianiaoeeoe/aneie noeioee?othuae e iauaoe?aieythuae oa?aiee niinianoaoao oiaiueoaieth o?iaiy yieoeca?iiai ai?iiia eae a ii/iie, oae e aeiaaiie ii?oeeyo ii/e, iiauoaieth niaea?aeaiey iieiauo, aiiaaeio?iiiuo ai?iiiia a e?iae e nooi/iie yene?aoeee 17-eaoinoa?ieaeia n ii/ie, a oaeaea eciaiaieth oa?aeoa?a ei??aeyoeeiiiuo acaeiinaycae iaeaoiieia n eco/aaiuie aeiioeca?iuie ai?iiiaie e iicaieyao iiauneoue yooaeoeaiinoue ea/aiey n 33.3% aei 52% /a?ac aiae io ia/aea ea/aiey. Eeth/aaua neiaa: iaeaoiiei, oee?eaaeiua ?eoiu, iieiaia nic?aaaiea, caaea?aeea iieiaiai ?acaeoey, ea/aiea caaea?aeee iieiaiai ?acaeoey. Turchina S.I. On the role of melatonin in sexual maturation and its delay formation in adolescent boys. - Manuscript Competitive Thesis for the Degree of Candidate of Sciences (Medicine). Speciality 14.01.14 - Endocrinology. V.P. Komissarenko Research Institute of Endocrinology and Metabolism of the Academy of Medical Sciences of Ukraine, Kyiv, 1999. The thesis dwells on the results of studying the role of melatonin in the mechanisms of male sexual system development and delayed sexual maturation formation in adolescent boys. It has been established that sexual maturation is accompanied by certain changes in melatonin daily release levels and in the character of its circadian rhythm. The existence of annual rhythm of melatonin production as well as correlation of daily rhythm pattern of the hormone excretion with the season has been demonstrated. In adolescents with delayed sexual development (DSD) melatonin content does not correspond to the reached level of biological maturity and depends on the stage of pathological process, morphotype and concomitant pathology. Annual rhythm of the hormone excretion in patients with DSD has a number of dissimilarities as compared with same in healthy boys of the same age. There has been suggested a principally new method of DSD treatment based on melatonin release suppression. Key words: melatonin, circadian rhythm, sexual maturation, delayed sexual development, method of delayed sexual development treatment.

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