I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo

aea?iaoieia?? oa aaia?ieia??

OAeE 615.276+615.454.1]:616.516.5

AI*A?IAA Ieaia Aiaoie??aia

II?OOAIIss NENOAIE AEEICAII?Ae?A O OAI?EO

IA IAE?IAeA?I?O, ?O ?IEUe A IAOIAAIAC? EE?I?*IEO I?IssA?A, AEA?? OAEOEEE
E?EOAAEUeII-I?IO?EAEOE*IEO CAOIAe?A

14.01.20 — oe??i? oa aaia?e/i? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a — 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia ia eaoaae?? oa?ai?? c eo?nii aea?iaoi-aaia?ieia??
Noinueeiai aea?aeaaiiai oi?aa?neoaoa

Iaoeiaee ea??aiee aeieoi? iaaee/ieo iaoe,

Iaa?ia Aaiaae?e ?aaiiae/,
caa?aeoth/ee

a?aeae?eaiiyi aaia?ieia??
Oe?a?inueeiai iaoeiai-

aeine?aeiiai ?inoeoooo
aea?iaoieia?? oa

aaia?ieia??

Io?oe?ei? iiiiaioe: ?iiaiaiei ??eia Ieoaee?aia, aeieoi? iaaee/ieo iaoe,
i?ioani? eaoaae?e oe??ieo oa aaia?e/ieo oai?ia Eoaainueeiai Aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo

Aieioia Ethaeieea Aiaoie??aia, aeieoi? iaaee/ieo iaoe, i?ioani?
eaoaae?e oe??ieo oa aaia?e/ieo oai?ia Oa?e?anueeiai ?inoeoooo
oaeineiiaeaiiy e?ea??a

I?ia?aeia onoaiiaa Iaoe?iiaeueiee iaaee/iee oi?aa?neoao

?i. aeaae. I.I.Aiaiiieueoey IIC Oe?a?ie, i.Ee?a

Caoeno a?aeaoaeaoueny 30 aa?aniy 1999 ?.i 12 aiae. 00 oa. ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae64.603.01 i?e Oe?a?inueeiio
iaoeiai-aeine?aeiiio ?inoeooo? aea?iaoieia?? oa aaia?ieia?? ca
aae?anith: 310057, i.Oa?e?a, aoe. *a?ieoaanueeiai 7/9 i 13 aiaeei?

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo aea?iaoieia?? oa aaia?ieia?? (i.Oa?e?a,
aoe. *a?ieoaanueeiai 7/9).

Aaoi?aoa?ao ?ic?neaii: 30 .08.99 ?.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio E. N. Oaoeueea

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie

Iae?iaea?i?o ? iaeiei c iaea?eueo ?iciianthaeaeaieo aea?aiaea?iaoic?a,
oa?aeoa?eco?oueny o?ii?/iei ia?aa?aii (c ei?ioeeie ?ai?n?yie, o?eaaeeie
?aoeeaeeaaie oa caaino?aiiyie), ?acenoaioi?noth aei o?aaeeoe?eii?
oa?ai??, ui iiaea i?ecaiaeeoe aei ?iaae?ae?caoe?? oai?eo (Aeooaiueeee
A.O., A?aiaei N.A., 1990; Eaethaeia E.Ae., 1990; E?aa/aiei E.A.,
Eiaaiianueeee A.?., 1998; Eieyaeaiei A.A., Ooiaiueei I.I.,
1981; Iaa?ia ?.?., Iaoio?ia I.A., 1982). E?euee?noue oai?eo a onueiio
na?o? c?inoa? (O?ooeiao?ee O., Aa?ia?ae Ae., 1993).

I?e ??ciiiai?oieo iai?yieao aeine?aeaeaiiy iaoiaaiaco oeueiai
aea?iaoico eeoa ie?ai? ?iaioe i?enay/ai? c’ynoaaiith ?ie? aeeicaii?ae?a
oa oeeee?/ieo ioeeaioeae?a a iaoai?ciao ?icaeoeo ee?i?/ieo i?iya?a
caoai?thaaiiy. A oie aea /an, c no/anieo iiceoe?e, naia aiie ? ia?ea?aie
iayaiino? caiaeueiiai, o oiio /ene? aea?a?/iiai i?ioeano
(i?inoaaeaiaeeie, eaeeio???ie), a?ae?a?athoue ?ieue oi?aa?naeueieo
iina?aaeiee?a ia?aaea/? ?ioi?iaoe?? a ee?oeie a on?o i?aaiao oa nenoaiao
i?aai?cio — oeeee?/i? ioeeaioeaee, Na++ (O?o?ia I.E., 1995; Na?e?nia
Ae.N., N??ia A.A., 1995; Enjalber A. et al., 1987).

Oyaeeee ia?aa?a iae?iaea?i?oo iaoiiaeaii aieeaii eiiieaeno
iani?eyoeeaeo iaoiaaiaoe/ieo oaeoi??a (aaiaoe/ia aeaoa?i?iiaai?noue,
iayai?noue caoai?thaaiue aai ooieoe?iiaeueieo ci?i aaaaoueio i?aai?a oa
nenoai i?aai?cio oa ?i.), ui aeeeoo? iaiao?aei?noue eiiieaeniiai
i?aeoiaeo aei ianoaaeaiiy, e?eoaaiiy oa aeeniaina?ecaoe?? oai?eo
(Aooa?iae/ I.I., Aooa?iae/ A.I., 1989).

O oie aea /an ua iaaeinoaoiuei i?eae?ey?oueny oaaae aeei?enoaiith
?ia?a?oi??a neioaco aeeicaii?ae?a i?e caaaeueiiio oa i?noeaaiio
e?eoaaii? oai?eo ia iae?iaea?i?o. I?aeoe/ii ia ?ic?iaeai? iaoiaee
aoi?eiii? i?io?eaeoeee iae?iaea?i?oo c o?aooaaiiyi noaio aeeicaii?aeii?
nenoaie oai?eo (Eacaeia A.I. oa ni?aaao., 1992; Ne?eie?i TH.E. oa
ni?aaao., 1995).

Oaeei /eiii, yaey?oueny aeooaeueiith oa i?aeoe/ii cia/eiith i?iaeaia
?ic?iaee iiaeo iaoiae?a e?eoaaiiy oa aoi?eiii? i?io?eaeoeee
iae?iaea?i?oo ia iniia? aea/aiiy ?ie? aeeicaii?ae?a a iaoiaaiac? oa
?icaeoeo ee?i?/ieo i?iya?a caoai?thaaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie

Aeena?oaoe?y ? o?aaiaioii eiiieaenii? IAe? eaoaae?e oa?ai?? c eo?nii
aea?iaoi-aaia?ieia?? Noinueeiai aea?aeaaiiai oi?aa?neoaoo, ?
aea?ae?a?no?aoe?? 0198V007720.

Iaoa ? caaaeaiiy aeine?aeaeaiiy

Iaoa aeine?aeaeaiiy — ?ic?iaeoe iiaee aoaeoeaiee aeinooiiee aeey
oe?ieiai cai?iaaaeaeaiiy o i?aeoeeo eiiieaeniee iaoiae e?eoaaiiy oa
aoi?eiii? i?io?eaeoeee iae?iaea?i?oo ?c aeei?enoaiiyi ?ia?a?oi??a
neioaco aeeicaii?ae?a, nei?ioeoe oa?i?i e?eoaaiiy oa iiaeiaaeeoe ?ai?n??
ca aeiiiiiaith aea/aiiy ?ie? ooieoe?iiaeueiiai noaio aeeicaii?aeii?
nenoaie o oai?eo ia iae?iaea?i?o.

Aeey aeinyaiaiiy iaoe aeine?aeaeaiiy iinoaaeai? oae? caaea/?:

1) aea/eoe aeaye? iaoiaaiaoe/i? oaeoi?e ?icaeoeo iae?iaea?i?oo
(ooieoe?iiaeueiee noai ie?aieo eaiie nenoai aeeicaii?ae?a oa aoi?eiieo
iina?aaeiee?a);

2) aea/eoe aieea aeeicaii?ae?a (IAA2, IAF2, EOA4) ia ?icaeoie ee?i?/ieo
iciae caoai?thaaiiy a oe??? i?e iae?iaea?i?o?;

3) ?ic?iaeoe iiaee eiiieaeniee iaoiae e?eoaaiiy oai?eo ia iae?iaea?i?o c
o?aooaaiiyi ooieoe?iiaeueiiai noaio nenoaie aeeicaii?ae?a, aea/eoe eiai
aoaeoeai?noue o ii??aiyii? c o?aaeeoe?eiei iaoiaeii;

4) aea/eoe aieea ?ic?iaeaiiai iiaiai iaoiaeo e?eoaaiiy ?c aeei?enoaiiyi
aioeaeeicaii?ae?a ia ooieoe?iiaeueiee noai nenoai aeeicaii?ae?a oa
aoi?eiieo iina?aaeiee?a o oai?eo ia iae?iaea?i?o;

5) ?ic?iaeoe iiaee iaoiae i?io?eaeoeee ?icaeoeo oyaeeeo ?aoeeaeea?a
iae?iaea?i?oo ?c canoinoaaiiyi aioeaeeicaii?ae?a oa aecia/eoe eiai
aoaeoeai?noue.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a

?ic?iaeaii iiaee aoaeoeaiee iaoiae e?eoaaiiy oai?eo ia iae?iaea?i?o c
eiiieaeniei (aioo??oi?i oa ciai?oi?i) aeei?enoaiiyi ?ia?a?oi??a neioaco
aeeicaii?ae?a.

Aia?oa c‘yniaai? iaoai?cie aieeao ?ia?a?oi??a neioaco aeeicaii?ae?a ia
eiiieaen iaoiaaiaoe/ieo oaeoi??a ?icaeoeo iae?iaea?i?oo.

?ic?iaeaii iiaee iaoiae aoi?eiii? i?io?eaeoeee iae?iaea?i?oo c
aeei?enoaiiyi aioeaeeicaii?aeii? oa?ai?? oa aecia/aia eiai ?ieue a
nenoai? aeeniaina?ecaoe?? iaoe??io?a.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a

?ic?iaeaii, ee?i?/ii ai?iaiaaii oa cai?iaaaeaeaii o i?aeoeeo iiaee
eiiieaeniee iaoiae oa?ai?? oai?eo ia iae?iaea?i?o ?c aeei?enoaiiyi
?ia?a?oi??a neioaco aeeicaii?ae?a, yeee aeicaiey? nei?ioeoe o?eaae?noue
e?eoaaiiy (ia 7-15 aei?a), caaacia/eoe aeia?ee iaeaeeae/?e ee?i?/iee
aoaeo (ee?i?/ia iaeoaeaiiy aai cia/ia iie?ioaiiy o 84,0%
iaoe??io?a).?ic?iaeaii iiaee eiiieaeniee iaoiae aoi?eiii? i?io?eaeoeee
iae?iaea?i?oo ?c aeei?enoaiiyi ?ia?a?oi?ii? aioeaeeicaii?aeii? oa?ai??,
yeee caaacia/o? o?eaaeo ?ai?n?th aai cia/ia ciaioaiiy nooiaith i?iya?a
?aoeeaeea?a o 80,0% oai?eo.

Iniaenoee aianie caeiaoaa/a

Aaoi?ii naiino?eii cae?eniaii aiae?c e?oa?aoo?e, caa?? iaoa??aeo,
aeeiiai? eiiieaeni? ?aae?i?ioii? aeine?aeaeaiiy noaio nenoai
aeeicaii?ae?a oa aoi?eiieo iina?aaeiee?a o oai?eo ia iae?iaea?i?o aei oa
i?ney e?eoaaiiy ??cieie iaoiaeaie, i?iaaaeaii e?eoaaiiy oai?eo ia
iae?iaea?i?o oa aeeniaina?iee iaaeyae ca ieie; aeeiiaii noaoenoe/iee
aiae?c iaea?aeaieo ?acoeueoao?a, noi?ioeueiaai? iniiai? aeniiaee
?iaioe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??

I?i?noa?noaii ioi?iie caei?ia’y Oe?a?ie aeaeaii ?ioi?iaoe?eiiai eenoa
“?ia?a?oi?ia aioeaeeicaii?aeia oa?ai?y oai?eo ia iae?iaea?i?o”.
Iaoa??aee aeena?oaoe?? aeeeaaeaii oa iaaiai?aii ia iaoeiaeo
eiioa?aioe?yo: “Aeooaeuei? i?iaeaie iaaeeoeeie Aeiiaano” (Aeiiaoeuee,
1995, 1996), iaoeiaeo eiioa?aioe?yo iaoeiaoe?a oa ni?a?ia?oiee?a
iaaee/iiai oaeoeueoaoo Noinueeiai aea?aeaaiiai oi?aa?neoaoo (Noie, 1997,
1998 ??.), iaoeiai-i?aeoe/ieo eiioa?aioe?yo aea?iaoi-aaia?ieia?a
Noinueei? iaeano? (1998, 1999 ??.).

?ic?iaeai? iaoiaee e?eoaaiiy oa aoi?eiii? i?io?eaeoeee iae?iaea?i?oo
ai?iaaaeaeaii aei i?aeoeee Aeiiaoeueeiai ?aa?iiaeueiiai
aea?iaoi-aaia?ieia?/iiai oeaio?o, Aeiiaoeueeiai, Oa?e?anueeiai,
Noinueeiai oa Aei?i?iiao?ianueeiai iaeanieo oe??ii-aaia?ieia?/ieo
aeeniaina??a, aeeoy/i? i?nueei? ee?i?/ii? e?ea?i? ? 1 i. Noie,
oeaio?aeueii? eo?i?oii? iie?ee?i?ee (i. ?aiaoi??y), a oaeiae — o
iaaeaaia?/iee i?ioean iaaee/ieo AOC?a (Aeiiaoeueeee aea?aeaaiee
iaaee/iee oi?aa?neoao, iaaee/iee oaeoeueoao Noinueeiai aea?aeaaiiai
oi?aa?neoaoo, Oa?e?anueeee ?inoeooo oaeineiiaeaiiy e?ea??a,
Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y).

Iniiai? iieiaeaiiy, ye? aeiinyoueny ia caoeno:

1. ?ieue aeeicaii?ae?a (i?inoaaeaiaeei?a A2, F2, eaeeio???io A4) a
iaoiaaiaoe/ieo iaoai?ciao ?icaeoeo ee?i?/ieo i?iya?a iae?iaea?i?oo.

2. Cia/aiiy oeeee?/ieo ioeeaioeae?a (oeAIO, oeAIO), Na++ a iaoai?ciao
iaoiaaiaoe/iiai aieeao aeeicaii?ae?a i?e iae?iaea?i?o?.

3. Aoaeoeai?noue eiiieaeniiai e?eoaaiiy oai?eo ia iae?iaea?i?o ?c
aeei?enoaiiyi ?ia?a?oi??a neioaco aeeicaii?ae?a.

Ioae?eaoe??

Ca iaoa??aeaie aeena?oaoe?? iaae?oeiaaii 9 ?ia?o, a oiio /ene?: 3 (1 —
naiino?eia) – o oaoiaeo iaoeiaeo aeo?iaeao, ?aeiiaiaeiaaieo AAE Oe?a?ie,
1 noaooy a ca??ieeo ?ia?o, 5 oac aeiiia?aeae.

No?oeoo?a aeena?oaoe??

Iiaiee ianya aeena?oaoe?? – 134 noi??iee, c ieo iaoeiiieno -115, 5
oaaeeoeue oa 31 ?enoiie. ?iaioa neeaaea?oueny ?c anooio, iaeyaeo
e?oa?aoo?e, 5 ?icae?e?a aeanieo aeine?aeaeaiue, caeeth/ii? /anoeie,
aeniiae?a, i?aeoe/ieo i?iiiceoe?e,nienea aeei?enoaieo aeaea?ae (100 —
a?o/eciyieo aaoi??a oa e?a?i NIAe, 70 — aeaeueiueiai ca?oa?aeaey).

?iaioa aeeiioaaeanue ia aacao Noinueei? i?nueei? ee?i?/ii? aeeoy/i?
e?ea?i? ? 1, Noinueeiai iaeaniiai oe??ii-aaia?ieia?/iiai aeeniaina?o,
Aeiiaoeueeiai ?aa?iiaeueiiai aea?iaoi-aaia?ieia?/iiai oeaio?o,
?aae?i?ioiieia?/ii? eaai?aoi??? Oeaio?o eaai?aoi?ii? ae?aaiinoeee
AeiiAeIO (aee?aeoi?, no.i.n., e.i.i. Cyae?oeaa N.A.).

INIIAIEE CI?NO AeENA?OAOe?EII? ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy.

O an?o oai?eo aei ii/aoeo e?eoaaiiy aeyaeyee nea?ae, aiaiiac oai?iae,
aeeooy. Ianoaaeoaaeenue: iiaa?oiy oe??e oa aeaeeieo neeciaeo iaieiiie,
ia?eoa??ei? e?ioaoe/i? aocee, noai aioo??oi?o i?aai?a oa nenoai,
i?iaiaeeeenue caaaeueiii?eeiyo? aiae?ce e?ia?, na/?, eaeo, ?aioaai
ianoaaeaiiy i?aai?a a?oaeii? ee?oeie, aei?ineei — na?ieia?/i?
ianoaaeaiiy ia neo?e?n.

Aeey e?euee?niiai aecia/aiiy nooiaith oyaeeino? i?ioeano i?e ia?aeiiiio
iaeyae? oa a aeeiai?oe? niinoa?aaeaiiy ca oai?eie (iaeaeeae/? oa
a?aeaeaeai? ?acoeueoaoe e?eoaaiiy), a oaeiae c iaoith c??aiyeueii?
iaoaiaoe/ii? ia?iaee io?eiaieo ee?i?/ieo ?acoeueoao?a canoiniaoaaeanue
oi?o?eiaaia i’yoeaaeueia nenoaia ioe?iee ia?aa?ao aea?iaoico, yea
a?aoiaoaaea ?aeiiaiaeaoe?? A.A.Aioii’?aa (1989 ?).

Oyaee?noue aea?iaoico aecia/aeanue ca oaeith oeaeith:

0 aae?a — a?aenooi?noue ee?i?/ieo i?iya?a aea?iaoico;

1 aae — ?aa?aae??ioiee ia?aa?a i?ioeano: ?aoeeaeeae iaio 1 ?aco ia ??e
oa ?ai?n?? o?eaae?noth a?eueo i?ae 1 ??e;

2 aaee — noaoe?iia?iee ia?aa?a: ?aoeeaeeae 1-2 ?ace ia ??e, o?eaae?noth
4-6 oeaei?a eiaeai, ei?ioei/ani? i?enooie naa?aaaeo iii??ii?
?ioaineaiino?, iaa?ioe/i? ?aaeoe?? ae?aaeai? neaaei, aac ii?ooaiue nio,
ieiua o?aaeaiiy 10-30% oe??ii? iiaa?oi?, o?eaae?noue ?ai?n?e — a?ae 3
aei 12 i?nyoe?a;

3 aaee — i?ia?aae??ioiee ia?aa?a aea?iaoico: iia?eueia i?ia?anoaaiiy
?aoeeaeeae 3-4 ?ace ia ??e, o?eaae?noth 8-10 oeaei?aeiaeiee,
?ioaineaiee naa?a?ae, iii??ii ae?aaeai? iaa?ioe/i? ?aaeoe?? oa ?iceaae
nio, ieiua o?aaeaiiy oe??ii? iiaa?oi? a?ae 30 aei 50%, o?eaae?noue
?ai?n?e a?ae 2 aei 3 i?nyoe?a;

4 aaee — i?ia?aae??ioiee ia?aa?a caoai?thaaiiy: oaeaeea i?ia?anoaaiiy,
iaeaea aacia?a?ai? ?aoeeaeeae o?eaae?noth 3 oa a?eueoa i?nyoe?a,
?ioaineaiee naa?a?ae, ?iceaae nio, ae?aaeai? iaa?ioe/i? ?aaeoe??,
aeneiaiiy ieiuath 50% ? a?eueoa.

Iaeeeae/? ?acoeueoaoe aoei oaeiae ioe?iaii ca 5-oe aaeueiith oeaeith:

0 aae?a — ee?i?/ia iaeoaeaiiy (iiaiee ?aa?an aeneio, iayai?noue eeoa
aoi?eiieo ieaiaioieo ieyi, cieeiaiiy naa?aaaeo, ii?iae?caoe?y
ineoi-o?c?ieia?/iiai noaio);

1 aae — cia/ia iie?auaiiy (a?aenooi?noue iiaeo oa ?aa?an oeo, ui aoee
aenei?a ?c caa??aaiiyi iacia/ii? ?io?eueo?aoe?? a ina?aaeeao o?aaeaiiy,
??aee? oa eaae? i?enooie naa?aaaeo aac iaa?ioe/ieo ?aaeoe?e oa ?iceaaeo
nio);

2 aaee — iie?auaiiy (a?aenooi?noue iiaeo oa ?aa?an oeo, ui aoee aenei?a
?c caa??aaiiyi iaaaeeei? ?io?eueo?aoe??, ei?ioei/ani? i?enooie naa?aaaeo
iii??ii? ?ioaineaiino?, ye? noi?iaiaeaeothoueny iacia/ieie iaa?ioe/ieie
?aaeoe?yie aac ?iceaaeo nio);

3 aaee — a?aenooi?noue nooo?aeo ci?i i?iya?a oai?iae;

4 aaee — iia??oaiiy i?io?eaiiy caoai?thaaiiy.

?iciiae?e oai?eo ii a?oiao i?iaiaeeany a caeaaeiino? a?ae iaoiaeo
oa?ai??.

Aeey aecia/aiiy e?eueeino? ai?noo a e?ia? aeeicaii?ae?a oa aoi?eiieo
iina?aaeiee?a, i?iaiaeeeenue aeine?aeaeaiiy ?c aeei?enoaiiyi
noaiaea?oieo ?aaeoea?a oa ?ao?aieea -?iioeuen?a “Gamma” (Oai?ueia).

Eiio?ieai aoee ?acoeueoaoe aeine?aeaeaiiy 30 caei?iaeo in?a (15
/ieia?e?a oa 15 ae?iie o a?oe? a?ae 16 aei 30 ?ie?a) – oaae.1

Aeey aeine?aeaeaiiy ai?noo a oe??? aeeicaii?ae?a (i?inoaaeaiaeei A2,
i?inoaaeaiaeei F2, eaeeio???i A4) i?iaiaeeee a?iin?th oe??e (c aeicaieo
iaoe??io?a) a iaaeao ai?aea?i?no. Aeine?aeaeaiith i?aeeyaaea oe??a o
ina?aaeeo o?aaeaiiy a iaeano? aa?oiuei? o?aoeie caeiaeueii? iiaa?oi?
ia?aaeie?//y oa neiao?e/ii ?icoaoiaaii? caei?iai? ia iiaeyae ae?eyiee.

Ca ii?io i?e ianoaaeaii? oe??e i?eeiaeenue aeani? aeai?, ye? aoei
io?eiaii i?e aeine?aeaeaii? a?iioao?a 10 caei?iaeo in?a-aeia?iaieueoe?a
(/ieia?e?a — 5, ae?iie — 5) o a?oe? a?ae 18 aei 25 ?ie?a, o yeeo oe??a
caae?aeanueii iaoiaeeoe?, aiaeia?/i?e aeey oai?eo (oaae.1).

Iaoaiaoe/ia ia?iaea aeine?aeaeaieo iieaciee?a aeeiiaia ca aeiiiiiaith
iaeaoo i?eeeaaeieo i?ia?ai “Office Professional 97” o??ie “Microsoft
Corporation” ia IE IBM ?N/AO. Ia/enethaaeenue iieacieee: na?aaeiy
a?eoiaoe/ia aaee/eia (I), na?aaei? eaaae?aoe/ia a?aeoeeaiiy (), iiieeea
aecia/aiiy na?aaeiuei? a?eoiaoe/ii? (m); ca aeiiiiiaith t-e?eoa??y
No’thaeaioa aecia/aee ??aaiue aeinoaiaiiino? ??cieoe? (?) ii??aiyeueieo
a?oiiaeo na?aaei?o; eiao?oe??io ei?aeyoe?? (r). (AEo?aaeueiaa E.?.,
1981).

Ci?no ?iaioe.

I?ae iaaeyaeii ciaoiaeeeinue 150 oai?eo ia iae?iaea?i?o: in?a /ieia?/i?
noao? — 54 (36,0%), ae?ii/i? — 96 (64,0%). A?eueo?noue iaoe??io?a aoee
aeeoy/iai oa i?aee?oeiaiai a?eo (113 /ieia?e – 75,4%).

Caoai?thaaiiy o ieo aoei o?eaaeei, oyaeeei, o?aaeeoe?eia e?eoaaiiy
aeaaaei eeoa oei/aniaee aoaeo, ui noi?iaiaeaeoaaeiny ?aii?ie
?aoeeaeeaaie.

Oai?? ia iae?iaea?i?o a caeaaeiino? a?ae iaoiaeo e?eoaaiiy aoee
?iciiae?eai? ia a?oie:

— 1-a, ii??aiyeueia, ui e?eoaaeanue o?aaeeoe?eieie iaaeeeaiaioicieie
caniaaie (30 oai?eo);

— 2-a, ii??aiyeueia, ui e?eoaaeanue eiiieaenii ?c canoinoaaiiyi
aioeaeeicaii?aeii? oa?ai?? aioo??oiuei? (35 oai?eo);

— 3-y, ii??aiyeueia, ui e?eoaaeanue eiiieaenii ?c canoinoaaiiyi
aioeaeeicaii?aeii? oa?ai?? ciai?oiuei? (35 oai?eo);

— 4-a (iniiaia), ui e?eoaaeanue eiiieaenii ?c canoinoaaiiyi
aioeaeeicaii?aeii? oa?ai?? ciai?oiuei? oa aioo??oiuei? (50 oai?eo).

?iciiae?e oai?eo ca a?eii, noaooth, o?eaae?noth, nooiaiai oyaeeino?
i?iya?a oa oi?iith caoai?thaaiiy o a?aenioeiaiio a?aeiioaii? a on?o
a?oiao aoa i?eaeecii iaeiaeiaei.

O?aaeeoe?eia iaaeeeaiaioicia oa?ai?y (1-a, ii??aiyeueia a?oia oai?eo)

O oe?e a?oi? oai?eo ia iae?iaea?i?o i?iaiaeeeinue eiiieaenia e?eoaaiiy
?c canoinoaaiiyi o?aaeeoe?eii? caaaeueii? oa i?noeaai? oa?ai??.

Eiiieaenia e?eoaaiiy c aeei?enoaiiyi ?ia?a?oi??a neioaco aeeicaii?ae?a
a caaaeuei?e oa?ai??? (2-a, ii??aiyeueia a?oia oai?eo)

Ae?oa?e ii??aiyeuei?e a?oi? oai?eo a nenoai? eiiieaeniiai e?eoaaiiy
i?ecia/aeenue ii?ioee “I?anioeee”, ye? aoee c?iaeai? a aioaoe? o
a?aeiia?aeiino? ?c neeaaeiaeie /anoeiaie oeueiai i?aia?aoo (i?aaei?cieii
– 0,00075a, oei?io?ia oinoao – 0,04a, aoeaoeenae?oeeeiaa eeneioa –
0,2a), o aeiaia?e aeic? o a?aeiia?aeiino? c a?eii oai?eo, yeo i?eeiaee a
4 i?eeiie ca aeaiue.

Eiiieaenia e?eoaaiiy c aeei?enoaiiyi ?ia?a?oi??a neioaco aeeicaii?ae?a
a ciai?oi?e oa?ai?? (3-y, ii??aiyeueia a?oia oai?eo).

O o?ao?e ii??aiyeuei?e a?oi? oai?eo e?eoaaiiy i?iaiaeeeinue ca oaeeie
ae i?eioeeiaie, ye ? ae?oa?e, aea “I?anioeee” i?ecia/aany o?eueee o
oi?i? 2% e?aio.

Eiiieaenia e?eoaaiiy c aeei?enoaiiyi ?ia?a?oi??a neioaco aeeicaii?ae?a
a caaaeuei?e oa ciai?oi?e oa?ai?? (4-a, iniiaia a?oia oai?eo)

O /aoaa?o?e (iniiai?e) a?oi? oai?eo i?iaiaeeeinue e?eoaaiiy c iiaoaiiei
aeei?enoaiiyi neeaaeiaeo /anoei “I?anioeeeo” a caaaeuei?e (aioo??oi?e)
oa?ai?? ca oaeeie i?eioeeiaie.

Ia 1-o aoai? (ii/aoie e?eoaaiiy) i?ae /an ?icaeiooi? ee?i?/ii? ea?oeie
iae?iaea?i?oo (3-4 aaee) a ii?ioeo aeei?enoiaoaaeenue on? neeaaeia?
/anoeie i?aia?aoo. Ia 2-o aoai? (cieaeaiiy ?ioaineaiino? i?iya?a
caoai?thaaiiy — naa?aey/ee, a?ia?ai?? oe??e – 2 aaee) c? neeaaeo
ii?ioe?a aeeeth/aany i?aaei?cieii. Ia 3-o aoai? (eiee caeeoaeenue eeoa
iii??i? i?iyae caoai?thaaiiy: neaaea naa?aey/ea, iacia/ia ?io?eueo?aoe?y
oe??e – 1 aae) c? neeaaeo ii?ioea aeeeth/aany oei?io?ia oinoao.
Aoeaoeenae?oeeeiaa eeneioa caeeoaeanue o neeaae? ii?ioea aei iiaiiai
(aai i?aeoe/ii iiaiiai) ?aa?ano ee?i?/ieo iciae caoai?thaaiiy. I?e
caaino?aii? i?ioeano iiaa?oaeenue aei ii?ioe?a 1-ai oa 2-ai aoai?a
e?eoaaiiy. Ciai?oiuei i?ecia/aany 2% i?anioeeeiaee e?ai.

Aaciina?aaeiuei i?ney cae?i/aiiy ia?oiai eo?no (iaeaeeae/? ?acoeueoaoe)
o 84,0% iaoe??io?a, ye? io?eioaaee iaeii/anii aioo??oi? oa ciai?oi?
aioeaeeicaii?aeia e?eoaaiiy, niinoa??aaeenue ee?i?/ia iaeoaeaiiy aai
cia/ia iie?ioaiiy. Oae? iieacieee i?e o?eueee aioo??oiueiio aeei?enoaii?
aioeaeeicaii?ae?a aoee o 74,3%, o?eueee i?e ciai?oiueiio — o 65,7%, aac
aioeaeeicaii?ae?a — 60,0% iaoe??io?a. O?eaae?noue e?eoaaiiy (a aeiyo) a
aeua cacia/aieo a?oiao aoea a?aeiia?aeii: 19,21,3; 25,61,6; 27,22,1;
34,2 2,6.

Oaeei /eiii, i?iaaaeaiiy eiiieaeniiai e?eoaaiiy ?c canoinoaaiiyi
aioeaeeicaii?aeii? oa?ai?? “I?anioeeeii” aeaaaei cia/ii e?au? (?<0,05) iaeaeeae/? ee?i?/i? ?acoeueoaoe a c??aiyii? c o?aaeeoe?eiith iaaeeeaiaioiciith iaoiaeeeith. I?e oeueiio naia iaeii/ania aeei?enoaiiy “I?anioeeeo” aioo??oiuei oa ciai?oiuei aoei iaea?eueo aoaeoeaiei, ? eiai ?acoeueoaoe aeinoaiaiii (?<0,01) a?ae??ciyeenue a?ae iieaciee?a o a?oiao oai?eo, aea aiie aeei?enoiaoaaeenue ie?aii (aioo??oiuei aai ciai?oiuei). O?eueee aioo??oi? aeei?enoaiiy “I?anioeeeo” a eiiieaeniiio e?eoaaii? oai?eo ia iae?iaea?i?o aeaaaei e?au? ?acoeueoaoe, i?ae o?eueee ciai?oi?, aea oea noaoenoe/ii ia aeinoaiaiii (?>0,05).

Aei oa i?ney e?eoaaiiy o 70 oai?eo ia iae?iaea?i?o (in?a /ieia?/i?
noao? — 30, ae?ii/i? — 40 — o a?oe? a?ae 16 aei 25 ?ie?a) a e?ia?
?aae?i?ioiiei iaoiaeii aecia/aany ai?no aoi?eiieo iina?aaeiee?a (oeAIO,
oeAIO, Na++), aeeicaii?ae?a (i?inoaaeaiaeeie A2, F2, eaeeio???i A4).
Iaeii/anii o 40 oai?eo o a?iioaoao oe??e ?c ina?aaeeo ooeiaeaeaiiy oa
neiao?e/ieo ae?eyiie oe??ii? iiaa?oi? aac aeneio, aea c iayai?noth
naa?aey/ee aeine?aeaeoaaee ai?no IAA2, IAF2, EO A4. Aeeiai?ea oeeo
iieaciee?a iaaeaia o oaaeeoe?.

Aei e?eoaaiiy o oai?eo ia iae?iaea?i?o aeyaeai? cia/i? aeinoaiaii?
(?<0,05-0,01) ci?ie iieaciee?a oeeo nenoai o e?ia?: o ne?iaaooe? - i?aeaeuaiiy ??aith Na2+ a na?aaeiueiio o 1,4 ?ace; o ieaci? - i?aeaeuaiiy IAA2 a na?aaeiueiio o 6,1, IAF2 - o 1,6, EOA4 - o 4,3, oeAIO - 5,6, cieaeaiiy oeAIO - o 4,4 ?ace. Ai?no a ae?eyieao ooeiaeaeaii? oe??e o oai?eo ia iae?iaea?i?o IAA2 aoa i?aeaeuaiei o na?aaeiueiio - o 3,8 ?ace, IAF2 - o 2,3 ?ace, EOA4 - o 5,9 ?ace (?<0,01-0,001). Ai?no aeeicaii?ae?a (IAA2, IAF2, EO A4) a ae?eyieao oe??e aac aeneio, aea c iayai?noth naa?aey/ee - ia a?ae??ciyany a?ae ii?ie. Cia/iee aeenaaeain a nenoaiao aoi?eiieo iina?aaeiee?a (i?e??no ??aiae oeAIO ? cieaeaiiy oeAIO) iiaea iaoe eeth/iaa cia/aiiy a iaoiaaiac? iae?iaea?i?oo ? a cia/i?e i??? aieeaaoe ia iieacieee aeeicaii?ae?a ye o ieaci? e?ia?, oae ? a oe???. Nooo?aa i?aeaeuaiiy ??aiae aeeicaii?ae?a (iniaeeai IAA2 oa EOA4) ye o ieaci? e?ia?, oae ? o oe??? ?c ina?aaee?a ooeiaeaeaiiy, na?ae/eoue i?i ?o aaciina?aaeith o/anoue o aea?a?/iiio caiaeueiiio i?ioean? i?e iae?iaea?i?o?. O oie aea /an aiie iathoue iaioa cia/aiiy o aeieeiaii? ii/oooy naa?aey/ee. sse na?ae/aoue aeai? oaaeeoe?, i?ney e?eoaaiiy ??cieie iaoiaeaie aeeiai?ea iieaciee?a ?aae?i?ioiieo aeine?aeaeaiue aoea iaiaeiaeiaa. Niinoa??aaeany iayaia oaiaeaioe?y aei cieaeaiiy aeeicaii?ae?a. O ii??aiyii? c aeo?aeieie iieacieeaie aiie ciaiooaaeenue: - i?ney eiiieaeniiai e?eoaaiiy o?aaeeoe?eieie iaaeeeaiaioicieie iaoiaeaie o ieaci? e?ia?: ??aaiue IAA2 o na?aaeiueiio a 1,8, IAF2 - o 1,3, EOA4 - o 2,1 ?ace; o oe??? a?aeiia?aeii: o 1,8; 1,6; 1,4 ?ace (?<0,01-0,05); - i?ney eiiieaeniiai e?eoaaiiy c aeei?enoaiiyi ii?ioe?a “I?anioeeeo” o ieaci? e?ia? a?aeiia?aeii: o 2,6, 1,5, 3,2 ?ace (?<0,05-0,01); o oe??? a?aeiia?aeii o 2,0, 1,4, 1,4 ?ace (?<0,05-0,01); - i?ney eiiieaeniiai e?eoaaiiy c aeei?enoaiiyi 2% i?anioeeeiaiai e?aio o ieaci? e?ia?, a?aeiia?aeii: o 2,4, 1,6, 2,8 ?ace; o oe??? a?aeiia?aeii: o 2,0, 1,4, 1,4 ?ace (?<0,05-0,01); - i?ney eiiieaeniiai e?eoaaiiy c iaeii/aniei aeei?enoaiiyi ii?ioe?a "I?anioeeeo" oa 2% i?anioeeeiaiai e?aio o ieaci? e?ia? a?aeiia?aeii: o 4,3, 1,6, 3,6 ?ace (?<0,05-0,01); o oe??? – aeinoaiaiii ia a?ae??ciyeenue a?ae o?c?ieia?/ieo (?>0,05).

I?ney e?eoaaiiy on?ia iaoiaeaie ??aaiue oeAIO iaa iayaio oaiaeaioe?th
aei ii?iae?caoe??, aai ii?iae?coaaany. ??aaiue oeAIO oi/a e cia/ii
cieaeoaaany, o ii??aiyii? c aeo?aeieie iieacieeaie (i?ney o?aaeeoe?eiiai
iaaeeeaiaioiciiai e?eoaaiiy — o 1,9 ?ace; i?ney aioeaeeicaii?aeii?
aioo??oiuei? aai ciai?oiuei? oa?ai?? — o 2,7, 2,5 ?ace), aea
ii?iae?coaaany o?eueee o iniiai?e a?oi? oai?eo, e?eiaaieo c iaeii/aniei
(aioo??oi?i oa ciai?oi?i) aeei?enoaiiyi aioeaeeicaii?ae?a (?<0,001). ??aaiue Na++ o ieaci? e?ia? oai?eo ia iae?iaea?i?o oaeoe/ii ii?iae?coaaany i?ney on?o aeae?a aioeaeeicaii?aeiiai e?eoaaiiy, ? iaeaea ia ci?ithaaany o a?oi? oai?eo, e?eiaaieo o?aaeeoe?eiei iaaeeeaiaioiciei iaoiaeii. Oaeei /eiii, i?aeaeuaiiy ai?noo aeeicaii?ae?a a ina?aaeeao ooeiaeaeaiiy oe??e i?e iae?iaea?i?o? iineoue aoi?eiiee oa?aeoa?, ine?eueee a ae?eyieao oe??e oeeo oai?eo aac iayaiino? aeneio ?o ??aaiue ia i?aeaeuo?oueny, a i?ney ?aa?ano aeneio a ooeiaeaeai?e oe??? - ii?iae?co?oueny. Aeei?enoaiiy aioeaeeicaii?aeii? oa?ai??, ye iieacothoue aeai? ?aae?i?ioiieia?/ieo aeine?aeaeaiue a?eueo aoaeoeaia, yeui ?? i?ecia/aoe iaeii/anii aioo??oiuei oa ciai?oiuei, ine?eueee o oeueiio ?ac? aiia iaea?eueo ?noioii aieeaa? ia iieacieee aeeicaii?ae?a o ieaci? oa oe??? oai?eo ia iae?iaea?i?o. I?e oeueiio caaacia/o?oueny eiiieaeniee aioeaeeicaii?aeiee aieea, ine?eueee ??ci? neeaaeia? /anoeie "I?anioeeeo" aieeaathoue ia ??ci? aoaie aeeicaii?aeiaaiaco: i?aaei?cieii - /a?ac e?iiei?oei i?eai?/o? ae?th oinoie?iace A2, ? ye ne?aenoai oeueiai - aeieo?oueny a?aeuaieaiiy a?ao?aeiiiai? eeneioe; aoeaoeenae?oeeeiaa eeneioa - aeieo? oeeeeiieneaaiaco, ? aiane?aeie oeueiai i?eieiy?oueny neioac i?inoaaeaiaeei?a; oei?io?ia oinoao - aaeueio? aea?eueiaiiy iiiiioeeaa?ieie ee?oeiaie ?ioa?eaee?io-1, ui iaiaaeo? aea?eueiaiiy i?inoaaeaiaeeio A2 (Aonaeue A.A., Ia?eiaa ?.A., 1989; Oa?eaae/ Ae.A., 1993; Eio?ain Ae., Aai?oo I., 1993). Aeeiai?ea iieaciee?a ?aae?i?ioiieo aeine?aeaeaiue ia? i?yi? ei?aeyoeai? ca’ycee c ?acoeueoaoaie e?eoaaiiy (iaeaeeae/?ie oa a?aeaeaeaieie), ui aeicaiey? ?? aeei?enoiaoaaoe ia o?eueee aeey ioe?iee aoaeoeaiino? e?eoaaiiy, a e aeey i?iaiico iiaeaeueoiai i?io?eaiiy caoai?thaaiiy (oaae.1). Aioeaeeicaii?aeia oa?ai?y (i?e iiya? ia?oeo iciae caaino?aiue aai ?aoeeaeea?a aea?iaoico a ia??iae aeeniaina?iiai iaaeyaeo) aeei?enoiaoaaeanue o oai?eo 2-?, 3-? oa 4-? a?oi ca oaeith iaoiaeeeith: ?i i?ecia/aany “I?anioeee” o aeicao a?aeiia?aeii a?eo 1 ?ac ia aeiao ia i?ioyc? 7-10 ae?a, a ia a?aeiia?aei? ae?eyiee ooeiaeaeaii? oe??e - 2% i?anioeeeiaee e?ai. Oai?ei 1-? ii??aiyeueii? a?oie aioeaeeicaii?aeia oa?ai?y ia i?iaiaeeeanue. Aeei?enoaiiy oaeeo caoiae?a caaacia/eei iaee?au? a?aeaeaeai? ee?i?/i? ?acoeueoaoe e?eoaaiiy (no?iee niinoa?aaeaiiy a?ae 1 aei 5 ?ie?a) o oai?eo 4-? a?oie, aeia?? - 2-? oa 3-? a?oi, iacia/i? - 1-? a?oie; o ieo na?aaei?e aae oyaeeino? ia?aa?ao aea?iaoico aoa a?aeiia?aeii 1,0, 1,46, 1,46 oa 3,20 (oaae.1). Oaeei /eiii, ee?i?/i? iane?aeee e?eoaaiiy (iaeaeeae/? oa a?aeaeaeai?) ? aeeiai?ea ooieoe?iiaeueiiai noaio nenoai aeeicaii?ae?a oa oeeee?/ieo ioeeaioeae?a na?ae/aoue i?i aenieo aoaeoeai?noue eiiieaenii? aioeaeeicaii?aeii? oa?ai?? oai?eo ia iae?iaea?i?o. Aiia aeicaiey? oaeiae i?e nai?/aniiio i?ecia/aii? cia/ii ciaioeoe nooi?iue oa /anoioo ?aoeeaeea?a i?ae /an aeeniaina?iiai iaaeyaeo. A E N I I A E E 1. O oai?eo ia iae?iaea?i?o aeyaeai? aeinoaiaii? ci?ie o ieaci? e?ia? ai?noo aeeicaii?ae?a oa aoi?eiieo iina?aaeiee?a (c?inoaiiy ??aiae i?inoaaeaiaeei?a A2 oa F2, eaeeio???io A4, oeAIO, cieaeaiiy oeAIO); o ne?iaaooe? e?ia? - i?aeaeuaiiy ??aith Na2+. 2. O oe??? oai?eo ia iae?iaea?i?o a ae?eyieao c iayai?noth aeneio oa naa?aey/ee aeinoaiaiii i?aeaeuaii ai?no i?inoaaeaiaeei?a A2 oa F2, eaeeio???io A4; a ae?eyieao oe??e c iayai?noth naa?aey/ee, aea aac aeneio ai?no aeeicaii?ae?a aeinoaiaiii ia a?ae??ciyany a?ae iieaciee?a o caei?iaeo in?a. 3. Aeei?enoaiiy “I?anioeeeo” o nenoai? eiiieaeniiai e?eoaaiiy oai?eo ia iae?iaea?i?o caaacia/o? nei?i/aiiy eiai o?eaaeino? ia 7-15 aei?a (a caeaaeiino? a?ae iaoiaeo) o c??aiyii? c o?aaeeoe?eiith iaaeeeaiaioiciith iaoiaeeeith; ee?i?/ia iaeoaeaiiy aai cia/ia iie?ioaiiy i?e o?aaeeoe?ei?e iaaeeeaiaioici?e iaoiaeeoe? niinoa??aaeinue o 60,0% iaoe??io?a, o?eueee aioo??oiueiio aeei?enoaii? aioeaeeicaii?ae?a - o 74,3%, o?eueee ciai?oiueiio - o 65,7%, iaeii/aniiio (aioo??oiueiio oa ciai?oiueiio) - o 84,0%. 4. Aioeaeeicaii?aeia oa?ai?y i?e iaeii/aniiio aeei?enoaii? ii?ioe?a "I?anioeeeo" oa 2% i?anioeeeiaiai e?aio o nenoai? eiiieaen-iiai e?eoaaiiy oai?eo ia iae?iaea?i?o iaea?eueo aoaeoeaii aieeaa? ia ooieoe?iiaeueiee noai nenoai aeeicaii?ae?a oa aoi?eiieo iina?aaeiee?a: o ii??aiyii? c aeo?aeieie aeaieie a e?ia? cieaeoaaeenue ??ai? i?inoaaeaiaeei?a A2 oa F2, eaeeio???io A4, Na2+, ii?iae?coaaeenue aai iaaeeaeoaaeenue aei o?c?ieia?/ieo aaee/ei - oeeee?/ieo ioeeaioeae?a; a ooeiaeaeaieo ae?eyieao oe??e ii?iae?coaaany ai?no aeeicaii?ae?a. 5. Aeei?enoaiiy aioeaeeicaii?ae?a i?e iiya? ia?oeo iciae ?aoeeaeea?a caoai?thaaiiy (i?ae /an aeeniaina?iiai iaaeyaeo) caaacia/o? cia/ii e?au? a?aeaeaeai? ee?i?/i? ?acoeueoaoe e?eoaaiiy oai?eo ia iae?iaea?i?o - no?eeo o?eaaeo ?ai?n?th aai cia/ia iie?ioaiiy eiai ia?aa?ao o 80,0% oai?eo, e?eiaaieo eiiieaenii c iaeii/aniei (aioo??oi?i oa ciai?oi?i) aeei?enoaiiyi “I?anioeeeo” (o?eueee i?e aioo??oiueiio aai ciai?oiueiio aeei?enoaii? - o 51,4%, aac aioeaeeicaii?ae?a - o 16,7%). Oaaeeoey 1 Aeeiai?ea iieaciee?a ai?noo aeeicaii?ae?a (o ieaci? e?ia? oa oe???), aoi?eiieo iina?aaeiee?a (o e?ia?) oai?eo ia iae?iaea?i?o oa na?aaei?e aae ioe?iee nooiaith oyaeeino? aea?iaoico. I?ei?oea: iieacieee aeinoaiaiiino? (?) - o oaeno? I?iaeiaaeaiiy oaae. 1 Aeeiai?ea iieaciee?a ai?noo aeeicaii?ae?a (o ieaci? e?ia? oa oe???), aoi?eiieo iina?aaeiee?a (o e?ia?) oai?eo ia iae?iaea?i?o oa na?aaei?e aae ioe?iee nooiaith oyaeeino? aea?iaoico. NIENIE IIOAE?EIAAIEO AAOI?II I?AOeUe CA OAIITH AeENA?OAOe?? 1. Ai/a?iaa I.A. Iaoiaaiaoe/ia cia/aiiy iae?iiaioeae?a oa i?inoaii?ae?a i?e aoii?/i?e oai?ia? // Aea?iaoi-aaia?ieia?y, einiaoieia?y, naeniiaoieia?y.- 1998.- ? 1.- N. 45-48. 2. Iaeioi?ua iaoiaaiaoe/aneea iaoaieciu aicieeiiaaiey coaea o aieueiuo o?iie/aneeie aea?iaoicaie /Eaaaaeeiaoe A.A., Aa?eaeiaa ?.E., Eeaoeiaa A.A. e ae?. - AEo?iae aea?iaoieiaee e aaia?ieiaee. – 1997. - ? 2/4.- N. 39-41. 3. Iiaay eiioeaioeey oi?ie?iaaiey coaeiaie ?aaeoeee i?e iaeioi?uo o?iie/aneeo aea?iaoicao /Ai/a?ia A.A., Cyaeeoeaa N.A., Aenyaei A.A. e ae?. - A?oea eeei. e yeni. iaae. - 1997.- O.6, Aui.1.-N. 113-116. 4. Aeaye? oaeoi?e o?ainoi?iaoe?? i?iya?a aoii?/iiai aea?iaoeoo/Ai/a?iaa I.A., Oeeaaiie A.A., Eoeueiica I.I., ?iaoeue I.I./ Iaoeia? caienee c ieoaiue iaaeeoeeie... (ui??/iee, aei. 1, /ano.1).- E., 1997.- N. 89-90. 5. Eaaaaeeiaoe A.A., Oneiaa E.A. ?ieue aei?eoii?aoeaenioa?aiee a nenoaia eiiieaeniiai ea/aiey aieueiuo aoiie/aneei aea?iaoeoii // Aeooaeueiua i?iaeaiu eeeie/aneie, yenia?eiaioaeueiie e i?ioeeaeoe/aneie iaaeeoeeiu: Oac. aeiee. 57-e eoiaiaie iao/i. nooae. eiio. Aeiiaoeeiai iaae. oi-oa. – Aeiiaoee, 1995. – N. 33 – 34. 6. Iaeioi?ua iiaua aniaeou iaoiaaiaca aoiie/aneiai aea?iaoeoa e yecaiu o ac?ineuo /Cyaeeoeaa N.A., Eiaia?enoue A.A., Aenyaei A.A. e ae?. - Nai?iee iao/i. o?oaeia iieiaeuo o/?iuo e niaoeeaeenoia, iinayu?iiuo 65-eaoeth Aeiiaoeeiai iaae. oi-oa. – Aeiiaoee, 1996. – N.12. 7. Eaaaaeeiaoe A.A. I oi?ie?iaaiee neiae?iia iae?i-yiaeie?eiiuo ia?ooaiee i?e aeennaieie?iaaiiii iae?iaea?ieoa // Aeo. i?iae. iaaeeoeeiu Aeiiaanna: Oac. aeiee. iao/i. eiio. - Aeiiaoee, 1996.- N.87-88. 8. Ai/a?iaa A.A. Iae?i-yiaeie?eiiue neiae?ii i?e aeennaieie-?iaaiiii iae?iaea?ieoa // Oac. aeiee. iao/i. eiio. ... NoiAO.- Noiu, 1997.- N.57-58. 9. Ai/a?iaa A.A., Oa?iiiieueneay N.I., O?enoaiei TH.A. Iaeioi?ua iieacaoaee iae?i-yiaeie?eiiuo nenoai o aieueiuo aoiie/aneei aea?iaoeoii // Oac. aeiee. iao/i. eiio. … NoiAO. – Noiu, 1998. – N.39. AIIOAOe?ss Ai/a?iaa I.A. Ii?ooaiiy nenoaie aeeicaii?ae?a o oai?eo ia iae?iaea?i?o, ?o ?ieue a iaoiaaiac? ee?i?/ieo i?iya?a, aea?? oaeoeee e?eoaaeueii-i?io?eaeoe/ieo caoiae?a. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaith eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.20 – oe??i? oa aaia?e/i? oai?iae. – Noinueeee aea?aeaaiee oi?aa?neoao, Noie, 1999. Aeena?oaoe?th i?enay/aii oaeineiiaeaiith iaoiae?a e?eoaaiiy iae?iaea?i?oo. Anoaiiaeaii ei?aeyoe?th i?ae oyaee?noth iaoieia?/iiai i?ioeano, ee?i?/iith aoaeoeai?noth e?eoaaiiy ? nooiaiai ii?ooaiue a nenoaiao aeeicaii?ae?a oa aoi?eiieo iina?aaeiee?a. ?ic?iaeaii oa cai?iaaaeaeaii o i?aeoeeo iiaee iaoiae eiiieaeniiai e?eoaaiiy oai?eo ia iae?iaea?i?o ?c aeei?enoaiiyi aioeaeeicaii?ae?a. Aoaeoeai?noue iaoiae?a oa?ai?? ioe?ithaaeanue ca nooiaiai ?aa?ano ee?i?/ii? ea?oeie aea?iaoico, aeeiai?eith iieaciee?a aeua cacia/aieo nenoai. Aeinyaiooi nei?i/aiiy o?eaaeino? e?eoaaiiy, iiaeiaaeaiiy o?eaaeino? ?ai?n??, nei?i/aiiy /enea oa nooiaiy ae?aciino? ?aoeeaeea?a o oai?eo ia iae?iaea?i?o. Eeth/ia? neiaa: iae?iaea?i?o, i?inoaaeaiaeei A2, i?inoaaeaiaeei F2, eaeeio???i A4, oeAIO, oeAIO, Na2+, i?anioeee. AIIIOAOeEss Ai/a?iaa A.A. Ia?ooaiey nenoaiu yeeicaiieaeia o aieueiuo iae?iaea?ieoii, eo ?ieue a iaoiaaiaca eeeie/aneeo i?iyaeaiee, auai? oaeoeee ea/aaii-i?ioeeaeoe/aneeo ia?ii?eyoee. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.20 – eiaeiua e aaia?e/aneea aieacie.- Noineie ainoaea?noaaii?e oieaa?neoao, Noiu, 1999. Aeenna?oaoeey iinayuaia oniaa?oainoaiaaieth iaoiaeia ea/aiey aieueiuo iae?iaea?ieoii e i?ioeeaeoeea ?aoeeaeeaia n o/?oii eciaiaiey a nenoaia yeeicaiieaeia (i?inoaaeaiaeeia A2 e F2?, eaeeio?eaia A4) a ieacia e?iae e ii?aaeaiiie eiaea. ?aaeeieiioiiui iaoiaeii a e?iae enneaaeiaaeenue oae aea o?iaie aoi?e/iuo iin?aaeieeia aeaenoaey yeeicaiieaeia – oeeeee/aneea ioeeaioeaeu (oeAIO, oeAIO) e eiiu Na2+. Aei ea/aiey o aieueiuo iae?iaea?ieoii auyaeaiu cia/eoaeueiua eciaiaiey iieacaoaeae yeeicaiieaeia e aoi?e/iuo iin?aaeieeia a e?iae: a nuai?ioea – iiauoaiea o?iaiae eiiia Na2+ a n?aaeiai a 1,4 ?aca; a ieacia – iiauoaiea IAA2 a n?aaeiai a 6,1, IA F2? - a 1,6, EOA4 - a 4,3, oeAIO – a 5,6, iiieaeaiea oeAIO – a 4,4 ?aca. Niaea?aeaiea a i/aaao ii?aaeaiey eiaee o aieueiuo iae?iaea?ieoii IAA2 auei iiauoaii a n?aaeiai a 3,8 ?aca, IAF2? – a 2,3, EOA4 – a 5,9 ?aca. Niaea?aeaiea yeeicaiieaeia a o/anoeao eiaee aac aunuiaiee ia ioee/aeinue io ii?iu. Aieueiua iae?iaea?ieoii a caaeneiinoe io iaoiaeia ea/aiey ?ani?aaeaeyeenue ia 4 a?oiiu: - 1-y, n?aaieoaeueiay, ea/aiiay eiiieaenii o?aaeeoeeiiiuie iaaeeeaiaioiciuie iaoiaeaie (30 aieueiuo); - 2-y, n?aaieoaeueiay, ea/aiiay eiiieaenii n i?eiaiaieai “I?anioeeea” aioo?ue (35 aieueiuo); - 3-y, n?aaieoaeueiay, ea/aiiay eiiieaenii n i?eiaiaieai 2% i?anioeeeiaiai e?aia ia?oaeii (35 aieueiuo); - 4-y, iniiaiay, ea/aiiay eiiieaenii n i?eiaiaieai “I?anioeeea” aioo?ue e 2% i?anioeeeiaiai e?aia ia?oaeii. Ninoaaiua /anoe “I?anioeeea” (i?aaeiecieii, oei?ioeia oinoao, aoeaoeenaeeoeeeiaay eeneioa) eiaeae?otho ?acee/iua iooe neioaca yeeicaiieaeia. Aieueiui iniiaiie a?oiiu ii?ioee “I?anioeeea” aioo?ue iacia/aeenue a iieiii ninoaaa ia ia?aii yoaia ea/aiey ai a?aiy ?aca??iooie eeeie/aneie ea?oeiu caaieaaaiey (ii 1-io ii?ioeo 4 ?aca a aeaiue a ?aciaie e nooi/iie aeica a caaeneiinoe io aic?anoa aieueiuo). Ia aoi?ii yoaia (nieaeaiea eioaineaiinoe i?iyaeaiey caaieaaaiey – coaea, aeia?aiee eiaee) ec ninoaaa ii?ioea eneeth/aeny i?aaeiecieii. Ia o?aoueai yoaia (eiaaea inoaaaeenue oia?aiiua i?iyaeaiey caaieaaaiey – iacia/eoaeueiue coae, iacia/eoaeueiay eioeeueo?aoeey eiaee) ec ninoaaa ii?ioea eneeth/aeny e oei?ioeia oinoao, a aoeaoeenaeeoeeeiaay eeneioa inoaaaeanue a ninoaaa ii?ioea aei iieiiai (eee i?aeoe/anee iieiiai) ?aa?anna eeeie/aneeo i?eciaeia caaieaaaiey. I?e iaino?aiee i?ioeanna aica?auaeenue e ii?ioeai ia?aiai eee aoi?iai yoaiia ea/aiey. Onoaiiaeaia ei??aeyoeaiay caaeneiinoue iaaeaeo noaiaiueth oyaeanoe oa/aiey iaoieiae/aneiai i?ioeanna e noaiaiueth eciaiaiey ooieoeeiiaeueiiai ninoiyiey nenoaiu yeeicaiieaeia: o aieueiuo n iaoieiae/aneeie iieacaoaeyie yeeicaiieaeia a ieacia e?iae e eiaea ioia/aeenue aieaa ooaeoea aeeaeaeoea e ioaeae?iiua ?acoeueoaou ea/aiey. N?aaieoaeueiay ioeaiea /aou??o iaoiaeia oa?aiee aieueiuo iae?iaea?ieoii (o?aaeeoeeiiiie iaaeeeaiaioiciie, eiiieaeniie n i?eiaiaieai “I?anioeeea” aioo?ue eee ia?oaeii a aeaea 2% e?aia, eee iaeiia?aiaiiui aai iacia/aieai a aeaea ii?ioeia per os e e?aia) iieacaea aieueooth yooaeoeaiinoue ni/aoaiiiai aioeyeeicaiieaeiiai ea/aiey a nenoaia eiiieaeniie oa?aiee. A aeeaeaeoai ia?eiaea iaaethaeaiey oaeay oa?aiey /aua iaania/eaaea eeeie/aneia aucaei?iaeaiea eee cia/eoaeueiia oeo/oaiea ninoiyiey aieueiuo (o 84,0% iniiaiie a?oiiu), cia/eoaeueii (ia 7 – 15 aeiae) ii n?aaiaieth n o?aaeeoeeiiiui iaoiaeii eee i?eiaiaieai “I?anioeeea” oieueei aioo?ue, eee oieueei a aeaea e?aia ia?oaeii nie?auaeanue i?iaeieaeeoaeueiinoue ea/aiey. A iniiaiie a?oiia aieueiuo /aua ii?iaeeciaaeenue iinea ea/aiey iieacaoaee nenoai yeeicaiieaeia e aoi?e/iuo iin?aaeieeia. Iacia/aiea “I?anioeeea” aioo?ue e 2% i?anioeeeiaiai e?aia ia?oaeii i?e i?iyaeaiee ia?auo i?eciaeia ?aoeeaeeaa caaieaaaiey i?aaeioa?auaei oyae?eia aai oa/aiea. Oaeia ea/aiea a ioaeae?iiii ia?eiaea iaaethaeaiey iaania/eaaei noieeoth ?aienneth eee cia/eoaeueiia oiaiueoaiea /enea e noaiaie oyaeanoe oa/aiey ?aoeeaeeaia aea?iaoica o 80,0% iaoeeaioia. Eeth/aaua neiaa: iae?iaea?ieo, i?inoaaeaiaeei A2, i?inoaaeaiaeei F2, eaeeio?eai A4, oeAIO, oeAIO, Na2+, i?anioeee. ANOTATION Bocharova E.A. The disorders of eucosanoids system in patients with neurodermit, their role in pathogenesis of clinical manifistation, the choice of treanment and prophilactic. - Manuscript. Thesis for scientific degree of Candidate of Medical Sciences by speciality of 14.01.20 – skin and veneral diseases.-Sumy State University, Sumy, 1999. The dissertation is devolted to the improvement of the cure methods of the neurodermit. The correlation between the heaviness of pathological process, the clinic effectiveness of treatment and the degree of violation in the system of eucosanoids and second mediators have been established. The new method of complex treatment neurodermit sickmen this antieucosanoids using has been worked out and inculcated. The effectiveness of therapie methods was being estimated by the degree of regress clinic picture of dermatose, and of the dinamic index of foregoing systems. The reduction of treatment duration, the remission prolongation the reduction of quantity and the degree of expressed retapses in the neurodermit sickmen has been achieved. The keywords: neurodermit, prostaglandin E2, prostaglandin F2, leukotrien B4, cAMP, cGMP, presocyl.

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