6

Oe?a?inueea aeaaeai?y aa?a?ieo iaoe

?inoeooo aenia?eiaioaeueii? ? ee?i?/ii?

aaoa?eia?ii? iaaeeoeeie

___________________________________________________________

A?ea ?iia Aeieo??aia

OAeE 619:616.98:578.831.3+616.995.132.8:636.4

iiaaiii?? naeiae, ni?e/eiai? anea?eni-

i?e?iaieie anioe?aoe?yie oa ?ic?iaea

i?io?eaeoe/ieo ? e?eoaaeueieo caoiae?a

03.00.18 – ia?aceoieia?y, aaeuei?ioieia?y

aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa aaoa?eia?ieo iaoe

OA?E?A — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a ?inoeooo? aenia?eiaioaeueii? ? ee?i?/ii? aaoa?eia?ii?
iaaeeoeeie Oe?a?inueei? aeaaeai?? aa?a?ieo iaoe.

Iaoeiaee ea??aiee:aeieoi? aaoa?eia?ieo iaoe, i?ioani? OAOIAOeIA A?oae?e
Noaiaiiae/, ?inoeooo aenia?eiaioaeueii? ? ee?i?/ii? aaoa?eia?ii?
iaaeeoeeie, caa?aeoaa/ eaai?aoi??? aaeuei?ioieia??

Io?oe?ei? iiiiaioe:aeieoi? aaoa?eia?ieo iaoe, i?ioani? A?OAIAIEI TH??e
A?eai?iae/, A?eioea?e?anueeee aea?aeaaiee aa?a?iee oi?aa?neoao,
caa?aeoaa/ eaoaae?e ia?aceoieia?? oa oa?iaeieia??

eaiaeeaeao aaoa?eia?ieo iaoe, aeioeaio IIIIIA?AIEI Aieiaeeie? sseiae/,
Oa?e?anueeee ciiaaoa?eia?iee ?inoeooo, aeioeaio eaoaae?e ia?aceoieia??

I?ia?aeia onoaiiaa:Euea?anueea aea?aeaaia aeaaeai?y aaoa?eia?ii?
iaaeeoeeie ?i. N. C. Aaeeoeueeiai I?i?noa?noaa aa?ii?iieneiaiai
eiiieaeno Oe?a?ie, eaoaae?a ia?aceoieia?? oa ?eaieoeoaa, i. Euea?a

Caoeno a?aeaoaeaoueny “ _22 ” __/a?aiy_______1999 ?. i ___15-00_
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.359.01 i?e
?inoeooo? aenia?eiaioaeueii? ? ee?i?/ii? aaoa?eia?ii? iaaeeoeeie OAAI:
310023, Oa?e?a-23, aoe. Iooe?inueea, 83.

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeoooo
aenia?eiaioaeueii? ? ee?i?/ii? aaoa?eia?ii? iaaeeoeeie OAAI (310023,
Oa?e?a-23, aoe. Iooe?inueea, 83).

Aaoi?aoa?ao ?ic?neaiee “_20_” ____o?aaiy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee,

aeieoi? aaoa?eia?ieo iaoe Eiia?aeaanueeee E.?.

caaaeueia oa?aeoa?enoeea ?iaioe

Aeooaeuei?noue. O oaia??oi?e /an iniaeeai aino?i iinoaea i?iaeaia
caaacia/aiiy ianaeaiiy eiieo?aioiini?iiiaeieie a?o/eciyieie i?iaeoeoaie
oa?/oaaiiy. O ae??oaii? oeueiai ieoaiiy aaeeea cia/aiiy iaaea?oueny
?icaeoeo iaei??th ?c aaeocae oaa?eiieoeueeiai ae?iaieoeoaa – naeia?noao
(?eaaeei, 1998). Ia aeaiee ia??iae iaaoee ?icaeoeo iaaaeee? naeia?nuee?
oa oa?ia?nuee? ainiiaea?noaa ii ae?iaieoeoao naeieie, a yeeo iaea?aeaiiy
caei?iaeo ii?inyo iiaeeeaa eeoa ca oiia noaa?eueiiai aeaaiiieo//y naeiae
uiaei ?iaac?eieo oa ?ioaeoe?eieo oai?ia (Aeioei, 1996; Aieee, 1997;
Naoeoeei, 1997).

?ani??aoi?ia iaoieia?y naeiae ? iaei??th c iaeaino??oeo i?iaeai a
aaoa?eia???. A?ae caaaeueii? caoai?thaaiino? aioo??oi?ie oai?iaaie ia ??
aeieth a ??cieo e?a?iao na?oo i?eiaaea?, a na?aaeiueiio, 30–60%. I?yi?
caeoee a?ae caaeaae? naeiae, ye? oai??ee ?ani??aoi?ieie oai?iaaie,
ia?aaeuothoue ye oae? a?ae on?o ?ioaeoe?eieo caoai?thaaiue (Aeoooe,
1982; Ionoiaa?, 1992; Naeaaineay, Naiei, 1993; I?eaiei, Ianoaiei, 1995
oa ?i.; Goodwin, 1985; Bernardo, Dohoo, Donald, 1990; Drovakova, 1993).

Ca aeaieie I. ss. I?eaiei oa ?i. (1993) ?ani??aoi?i? oai?iae naeiae o
ainiiaea?noaao oa oa?iao Oe?a?ie caeiathoue aeii?ioth/a iieiaeaiiy a
?ioaeoe?ei?e iaoieia?? ?o ? neeaaeathoue, o na?aaeiueiio, 29–32% a?ae
/enea an?o ca?acieo caoai?thaaiue, ni?e/eithth/e aaeee? aeiiii?/i?
caeoee. A naeia?nueeeo ainiiaea?noaao, iaaeaaiiieo/ieo ia iiaaiii??, ca
aeaieie oeeo aea aaoi??a, /ano?oa anueiai anoaiiaeaia ?o a??onia,
aaeoa??aeueia, a oaeiae a??onii-aaeoa??aeueia i?e?iaea.

A cia/i?e i??? ?icaeoie oeeo caoai?thaaiue oneeaaeith?oueny
iaaeio?eiaiiyi ciia?a??i?/ieo ii?i aiae?ae? oa oo?eiaiiyi oaa?ei, ui
i?ecaiaeeoue aei iiieaeaiiy caaaeueii? oa niaoeeo?/ii? ?acenoaioiino?
i?aai?cio (Anoaoiaa, 1991) ? iineeaiiy iaoiaaiii? ae?? ??cieo
i?e?ii?aai?ci?a.

?yae aaoi??a (Zimmermann, 1985; Jung et al., 1984, Springer, 1992)
ia?aeiio ?ieue o aeieeiaii? oa ?icaeoeo iiaaiii?? a?aeaiaeyoue ee/eieai
A. suum. ?io? aeine?aeieee aaaaeathoue, ui aiie eeoa noai?ththoue oiiae,
ye? i?iaieothoue ?icaeoie ?ioaeoe??, yea aeeeeea?oueny a??onaie,
aaeoa??yie, i?eiieaciaie oa ?o anioe?aoe??th (ssoonaae/ e ae?., 1995;
Iaiiaiiaa, 1997; Biehl, 1988; Taylor, Purchase, 1990). Ia aeoieo N.
Aoco?na (Eustis, 1982) ee/eiee A. suum ? aaaeeeaei i?iaieaoe?eiei
oaeoi?ii o ?icaeoeo iiaaiii?? ii?inyo, aea ?? i?iya caeaaeeoue ye a?ae
e?eueeino? ?iaac?eieo y?oeue, ye? iio?aieee a i?aai?ci oaa?ei, oae ?
??aiy niaoeeo?/ii? ?acenoaioiino? i?aai?cio ii?inyo.

Cia/aiiy aaeuei?io?a oa ?o i?a?oth/eo ee/eiie a ao?ieia?? ?ani??aoi?ii?
iaoieia?? naeiae aei oeueiai /ano aea/aii iaaeinoaoiuei. Oiio, i?e
?ic?iaoe? e?eoaaeueii-i?io?eaeoe/ieo caoiae?a ai?ioueae c iiaaiii?yie
ii?inyo iaiao?aeii a?aoiaoaaoe, ui a iie?ao?ieia?/iino? aeaiiai
caoai?thaaiiy aeoaea aeooaeueiei ? aecia/aiiy ?ie? ee/eiie A. suum a
?icaeoeo iaoieia?/iiai i?ioeano a eaaaiyo.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeine?aeaeaiiy
ii aeena?oaoe?ei?e ?iaio? i?iaiaeeeeny o a?aeiia?aeiino? c
ani??aionueeith oaiith, aeeth/aiith a iaoeiai-aeine?aeio i?ia?aio
eaai?aoi??? aaeuei?ioieia?? ?AEAI OAAI ca 1996–1998 ??. (oeo? 08).

Iaoa ? caaea/? aeine?aeaeaiiy. Iniiaiith iaoith iaoeiaeo aeine?aeaeaiue
aoei anoaiiaeaiiy ?ie? i?a?oth/eo ee/eiie A. suum, ye ie?aii, oae ? a
anioe?aoe?? c aeae?eaieie ?c eaaai?a oai?eo naeiae i?e?ii?aai?ciaie, o
aeieeiaii? iiaaiii?e naeiae a oiiaao ainiiaea?noa oa oeyoii
aenia?eiaioaeueiiai ca?aaeaiiy oaa?ei ? ?ic?iaea i?io?eaeoe/ieo oa
e?eoaaeueieo caoiae?a.

O ca’yceo c oeei, ia?aae iaie aoee iinoaaeai? oae? caaaeaiiy:

— aea/eoe ai?ciioe/io neooaoe?th noiniaii anea?eico oa ca’ycie ?? c
?iciianthaeaeaiiyi iiaaiii?e o naeia?nueeeo ainiiaea?noaao ??ciiai oeio
? anoaiiaeoe iniaeeaino? ee?i?/ieo i?iya?a ? iaoieiai-aiaoii?/ieo ci?i
i?e oeeo caoai?thaaiiyo oa i?iaanoe aaeoa??ieia?/i? aeine?aeaeaiiy
iaoa??aeo, a?ae?a?aiiai a?ae oai?eo ia iiaaiii?th naeiae;

— aecia/eoe ?ieue i?a?oth/eo ee/eiie A. suum, ye ie?aii, oae ? a
anioe?aoe?? c aeae?eaieie ?c eaaai?a oai?eo ia iiaaiii?th naeiae
i?e?ii?aai?ciaie oa a?aeoai?eoe ca aeiiiiiaith ?o oea caoai?thaaiiy
oeyoii aenia?eiaioaeueiiai ca?aaeaiiy oaa?ei;

— a aenia?eiaioaeueieo oiiaao aea/eoe aieea i?a?oth/eo ee/eiie A. suum
ia aaiaoieia?/i? oa ?ioiieia?/i? iieacieee;

— aei?iaoaaoe o ae?iaie/eo oiiaao iaea?eueo aoaeoeai? oa?aiaaoe/i?
caniae aeey e?eoaaiiy naeiae c anioe?aoeaieie iiaaiii?yie;

— onoaiiaeoe ?aoe?iiaeuei? no?iee ? ?ic?iaeoe noaie i?a?iaa?iaeueii?
aeaaaeuei?ioecaoe?? aeey i?io?eaeoeee iiaaiii?? o naeiae a
ainiiaea?noaao, iaaeaaiiieo/ieo uiaei anea?eico;

 i?iaanoe ii??aiyeueio ioe?ieo aoaeoeaiino? canoinoaaiiy ??cieo
e?eoaaeueii-i?io?eaeoe/ieo ? ?ioiiiiaeoethth/eo i?aia?ao?a c o?aooaaiiyi
iiia?aaeiuei iaea?aeaieo ?acoeueoao?a aaiaoieia?/ieo oa ?ioiieia?/ieo
aeine?aeaeaiue.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa aoee iaea?aeai? aeai?
i?i ?iciianthaeaeaiiy iiaaiii?e a ainiiaea?noaao ??ciiai oeio,
iaaeaaiiieo/ieo uiaei anea?eico naeiae, a oaeiae anoaiiaeaia a
aeine?aeao, i?iaaaeaieo a eaai?aoi?ieo ? ae?iaie/eo oiiaao aaaeeeaa
?ieue ee/eiie A. suum o aeieeiaii? iiaaiii?? o ii?inyo, oneeaaeiaii?
oiiaii-iaoiaaiiith i?e?ioei?ith. Anoaiiaeaiee aca?iica’ycie i?ae
aenoaineai?noth anea?eicii? ?iaac?? ? ??aiai caoai?thaaiino? iiaaiii?yie
o ii?inyo 2–4-i?ny/iiai a?eo, a oaeiae i?ae aenoaineai?noth ?
?ioaineai?noth ?iaacoaaiiy ee/eieaie anea?en?a c i?iyaii iiaaiii?e o
ii?inyo-nenoi?a. Aea/aii ?ioiia?ieia?/iee noai i?aai?cio naeiae i?ney
anioe?aoeaiiai ca?aaeaiiy ii?inyo eoeueoo?aie ?iaac?eieo y?oeue A. suum
? aaeoa??ie – S. aureus oa E. coli. ?ic?iaeai? eiiieaeni? caoiaee
i?io?eaeoeee ? e?eoaaiiy naeiae c anioe?aoeaieie iiaaiii?yie, ye?
aeeth/athoue canoinoaaiiy iiaeo aoaeoeaieo aioaaeuei?ioee?a,
aioea?ioee?a oa ?ioiinoeioeyoi?a.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Ia i?aenoaa? i?iaaaeaieo
aeine?aeaeaiue iaie cai?iiiiiaai? aeey ai?iaaaeaeaiiy o ae?iaie/eo
oiiaao aoaeoeai? eiiieaeni? e?eoaaeueii-i?io?eaeoe/i? noaie, c
aeeth/aiiyi ??cieo i?aia?ao?a oa iioeiaeueieo no?ie?a ?o canoinoaaiiy
i?e anioe?aoeaieo iiaaiii?yo naeiae. Ia iniia? iaea?aeaieo ?acoeueoao?a
a eaai?aoi?ieo ? ae?iaie/eo oiiaao ?ic?iaeai? “?aeiiaiaeaoe?? ii
i?io?eaeoeoe? ? e?eoaaiith anea?eni-i?e?iaieo iiaaiii?e o naeiae”, ye?
noaaeai? oa caoaa?aeaeai? a/aiith ?aaeith ?AEAI OAAI (i?ioieie ? 3 a?ae
26 aa?aciy 1999 ?.) ? ai?iaaaeaeai? a 2-o ainiiaea?noaao Oa?e?anueei?
iaeano? c iiceoeaieie ?acoeueoaoaie.

Cai?iiiiiaaia iiaeeo?eaoe?y eoeueoeaoaaiiy y?oeue A. suum aei ?iaac?eii?
noaae??.

Iniaenoee aianie caeiaoaa/a. Iniaenoee aianie aeena?oaioa iieyaa? a
naiino?eiiio aeeiiaii? anueiai caieaiiaaiiai ia’?io iaoiaee/ii? oa
aenia?eiaioaeueii? ?iaioe, iaa?oiooaaii? oa aiae?c? iaea?aeaieo
?acoeueoao?a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe aeine?aeaeaiue,
aeeeaaeai? o aeena?oaoe??, caneooai? oa iaaiai?ai? ia can?aeaiiyo
iaoiaee/ii? oa a/aii? ?aae ?AEAI OAAI (1996–1998 ??.), ia i?aeia?iaei?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? iieiaeeo a/aieo “Iaoeia? aeinyaiaiiy a
aaeoc? aaoa?eia?ii? iaaeeoeeie” (1–2 ea?oiy 1997 ?., i. Oa?e?a), ia 5-e
i?aec’?caeia?e eiioa?aioe?? ia?aceoioeaiieia?a Oe?a?ie “I?iaeaie ?
ia?niaeoeae ia?aceoioeaiieia??” (29–30 aeiaoiy 1997 ?., i. Eoaainuee).

No?oeoo?a ? ianya aeena?oaoe??. Iaoa??aee aeena?oaoe?eii? ?iaioe
aeeeaaeai? ia 152 noi??ieao iaoeiiieniiai oaenoo ? i?noyoue anooi,
iaeyae e?oa?aoo?e, aeani? aeine?aeaeaiiy, aeniiaee, nienie aeei?enoaieo
aeaea?ae ? aeiaeaoee. Nienie aeei?enoaii? e?oa?aoo?e aeeth/a? 342
aeaea?aea, a oiio /ene? 143 ?iicaiieo aaoi??a.

?iaioa ?ethno?iaaia 34 oaaeeoeyie oa 11 ?enoieaie.

Ioae?eaoe??. Ii oai? aeena?oaoe?? iioae?eiaaii 9 ?ia?o, ?c ieo 6 noaoae
a oaoiaeo aeaeaiiyo.

AEANI? AeINE?AeAEAIIss

Iaoa??aee ? iaoiaee

C iaoith aea/aiiy ?iciianthaeaeaiiy anea?eico oa anioe?aoeaieo iiaaiii?e
o naeiae ia i?ioyc? 1996–1998 ??. a 8 ainiiaea?noaao ??ciiai oeio
Oa?e?anueei? iaeano? aoee i?iaaaeai? aaeuei?ioieii?ineii?/i? ?
iaoieiai-aiaoii?/i? aeine?aeaeaiiy oa ee?i?/i? ianoaaeaiiy
naeiiiiaie?a’y. ?iaioo ii aea/aiith naciiii? oa a?eiai? aeeiai?ee
anea?eico i?iaiaeeee ia aac? 3-o ainiiaea?noa, aeaaiiieo/ieo ii
?ioaeoe?eiei oai?iaai oa ??cieie ii oaoiieia?? ae?iuoaaiiy ?
/enaeueiino? iiaie?a’y: niaoe?ae?ciaaiiio ii ae?iaieoeoao naeieie,
aaaaoiaaeocaaiio oa o/aiai-aeine?aeiiio. O oeeo ainiiaea?noaao uii?ny/ii
i?iaiaeeee a?aea?? i?ia oaeae?e a?ae oaa?ei ??cieo a?eiaeo a?oi (ii?inyo
aei 2-o i?nyoe?a, 2–4 i?nyoe?, a?ae 5 aei 8 i?nyoe?a oa naeiiiaoie –
ii?inieo oa i?aenenieo) ? aeine?aeaeoaaee noaiaea?oeciaaiei iaoiaeii
A. A. Eioaeueieeiaa oa A. I. O?aiiaa (1982). Anueiai i?iaaaeaii 7386
eii?ineii?/ieo aeine?aeaeaiue oaeae?e naeiae. O oeeo ainiiaea?noaao
cae?enithaaee ee?i?/iee iaeyae naeiae caaaeaieo a?eiaeo a?oi, aecia/aee
e?euee?noue oaa?ei c ?ani??aoi?iith iaoieia??th, ia?aa?a caoai?thaaiiy,
i?iaiaeeee ?icoei caaeaeeo oa aeiooaii caaeoeo ii?inyo, oai?eo ia
iiaaiii?th. Ee?i?/ii ianoaaeaii 10662 aie?a oaa?ei,
iaoieiai-aiaoii?/iiio ?icoeio i?aeaeaii 302 aieiae.

Aeey aecia/aiiy iayaiino? i?a?oth/eo ee/eiie A. suum a i?aaiao
aeei?enoiaoaaee iaoiae ia?ao?aaeaiiy o ooo/iiio oeoieiaiio nieo
(Ni??iia, 1975). Aaeoa??ieia?/i? aeine?aeaeaiiy iaoieia?/iiai iaoa??aeo,
a?ae?a?aiiai a?ae oai?eo ia iiaaiii?th naeiae i?iaiaeeee o ?aeiiieo ?
iaeani?e eaai?aoi??yo aaoa?eia?ii? iaaeeoeeie oa eaai?aoi???
i?e?ia?ieia?? ? ?ioiieia?? ?AEAI OAAI i?ae ea??aieoeoaii i?io. E.?.
Eiia?aeaanueeiai.

Aeey a?aeoai?aiiy anea?eicii? iiaaiii?? a aenia?eiaioaeueieo oiiaao
i?iaiaeeee eoeueoeaoaaiiy y?oeue A. suum aei ?iaac?eii? noaae?? ca?aeii
c iaoiaeeeith, iienaiith A. A. Anoaoueaaei, E. N. ss?ioeueeei oa I. I.
Eaaaae?aei (1989), a iao?e iiaeeo?eaoe??.

Ee?i?ei-aenia?eiaioaeuei? aeine?aee ii a?aeoai?aiith anea?eicii?
iiaaiii?? i?iaiaeeee ia a?oi? ii?inyo-nenoi?a aaeeei? a?ei? ii?iaee,
i?ae?a?aieo ca i?eioeeiii aiaeia?a, o a?oe? 26–28 ae?a, yeeo ca?aaeaee
ia?i?aeueii eoeueoo?ith ?iaac?eieo y?oeue A. suum (c ?ic?aooieo ? 2000
?iaac?eieo y?oeue ia 1 ea iane o?ea).

Aeey a?aeoai?aiiy anioe?aoeaieo iiaaiii?e a oiiaao aenia?eiaioo
i?iaiaeeee ca?aaeaiiy ii?inyo eoeueoo?aie ?iaac?eieo y?oeue A. suum oa
aaeoa??yie S. aureus oa E. coli ye ie?aii, oae ? noi?nii. I?e?ii?aai?cie
aeae?eeee c eaaaiue ii?inyo, oai?eo ia iiaaiii?th, a yeeo ciaoiaeeee
ee/eiie A. suum. I?e oeueiio aoei aeei?enoaii 29 ?ioaeoieo ii?inyo
oaeiae 26–28-aeaiiiai a?eo, c yeeo noi?ioaaee 4 aeine?aei? a?oie.
Ii?inyoai ia?oi? a?oie (8 aie?a) ia ia?oo aeiao aaiaeeee
?io?ao?aoaaeueii, a ia ae?oao oa o?aoth aeiao – ?io?aiacaeueii
noniaic?th aeiaiai? aaa?iai? eoeueoo?e cieioenoiai noao?eieieo o aeic?
10 ie?ae. i. o. a 1 ni3. Ae?oa?e a?oi? oaa?ei (8 aie?a) o oae?e aea
iine?aeiaiino? oa aeic? aaiaeeee aeiaiao eoeueoo?o eeoeiai? iaee/ee.
Ii?inyo o?aouei? a?oie (8 aie?a) iaeii/anii ca?aaeaee ca oaeith ae
noaiith eoeueoo?aie S. aureus ? E. coli a aeic? 10 ie?ae. i. o. a 1 ni3,
a ia o?aoth aeiao aaiaeeee ?iaac?ei? yeoey A. suum ia?i?aeueii o aeic?
? 2000 y?oeue ia 1 ea iane o?ea. Oaa?eiai eiio?ieueii? a?oie (5 aie?a)
aaiaeeee noa?eeueiee o?c?ieia?/iee ?ic/ei a ia’?i? 1 ni3 ii aiaeia?/i?e
noai?. Aei ca?aaeaiiy oa i?ney iueiai ia 5, 12, 20, 36 oa 45-oo aeiao o
naeiae a?aeae?aee c ia?aaeiuei? ii?iaeienoi? aaie e?ia aeey i?iaaaeaiiy
aaiaoieia?/ieo ? ?ioiieia?/ieo aeine?aeaeaiue oa aaee ca ieie ee?i?/i?
niinoa?aaeaiiy. O oe? no?iee i?iaiaeeee caa?e oaa?ei c iine?aeoth/eie
a?noiii?oieia?/ieie oa aaeoa??ieia?/ieie aeine?aeaeaiiyie o?aaeaieo
ae?eyiie eaaaiue.

Aaiaoieia?/i? aeine?aeaeaiiy cae?enithaaee ca caaaeueiii?eeiyoeie
iaoiaeeeaie, aecia/aiiy ai?noo O-e?ioioeeo?a ca I. I. Oeeiaaeii c
ni?aaaoi?. (1983), A-e?ioioeeo?a – ca Ae. E. Iia?eiaei oa A. ?.
Iia?eiaith (1979), caaaeueiee a?eie – ?ao?aeoiiao?e/ii, ?ioiiaeiaoe?ie
eeano I oa G – ca O. Iai/?i? (Mancini, 1965), oee?eoethth/? ?ioii?
eiiieaene – ca TH. A. A?eiaae/ai oa I. ?. Aeouei?iaith (1980).

?ioiieia?/i? aeine?aeaeaiiy i?iaiaeeee ni?eueii c ni?a?ia?oieeaie
eaai?aoi??e a?io?i?? ? i?e?ia?ieia?? oa ?ioiieia?? ?AEAI OAAI.

Iaoiii?oieia?/i? aeine?aeaeaiiy i?aai?a i?iaiaeeee o eaai?aoi???
iaoiii?oieia?? ?AEAI OAAI ni?eueii c aeaaeai?eii A. A. E?ani?eiaei.

Aea/aiiy aoaeoeaiino? e?eoaaiiy ii?inyo, oai?eo ia iiaaiii?th,
i?iaiaeeee a oiiaao 2-o aeaaiiieo/ieo ii ?ioaeoe?eiei oai?iaai
ainiiaea?noa, canoiniaoth/e aioaaeuei?ioeee, aioea?ioeee,
?ioiinoeioeyoi? ye ie?aii, oae ? eiiieaenii. O aeine?ae? aoee
aeei?enoai? ii?inyoa 30–40-aeaiiiai a?eo. C aioaaeuei?ioee?a
canoiniaoaaee iaiaeo?, aeaeoiiaen, o?cieaaai?cie, oethaaiie 5%,
oao?ai?cie; c aioea?ioee?a – “Eeaiienee” oa “Aaeo?ee”; ?ioiinoeioeyoi? –
iaoeeo?aoeee. Aioaaeuei?ioeee a aenia?eiaio? caaeaaaee ?iaeea?aeoaeueiei
iaoiaeii iaeii?aciai, a o ae?iaie/iio aeine?ae? – a?oiiaei,
iiae??aiaieie aeicaie c eiioeaio?iaaieie ei?iaie, ca aeeeth/aiiyi
aeaeoiiaeno oa o?cieaaai?cieo, ye? aaiaeeee aioo??oiueii’yciai.
Aioea?ioeee canoiniaoaaee o aeicao, ?aeiiaiaeiaaieo o a?aeiia?aeieo
ianoaiiaao, aea c ??ciith iine?aeiai?noth, a iaoeeo?aoeee caaeaaaee
i?ioyaii 14 ae?a i?ae?yae.

Aoaeoeai?noue e?eoaaiiy aecia/aee ia i?aenoaa? ee?i?/ieo iciae,
caa?aaeaiino? oaa?ei o a?oiao, iaea?aeaiiai i?e?inoo iane o?ea,
aaeuei?ioieii?ineii?/ieo aeine?aeaeaiue, a oaeiae c o?aooaaiiyi
aaiaoieia?/ieo oa ?ioiieia?/ieo iieaciee?a.

?ic?iaeo i?a?iaa?iaeueieo aeaaaeuei?ioecaoe?e, ye iaeiiai ?c cania?a
i?io?eaeoeee iiaaiii?e, i?iaiaeeee a ainiiaea?noaao, iaaeaaiiieo/ieo
uiaei anea?eico ? iiaaiii?e naeiae, ia ii?inyoao 14–15- oa 30-aeaiiiai
a?eo c aeei?enoaiiyi aioaaeuei?ioee?a oe?iei niaeo?o ae??, ye ie?aii,
oae ? ?acii c ?ioiinoeioeyoi?ii. Aioaaeuei?ioeee aeei?enoiaoaaee o
aenia?eiaioaeueiiio aeine?ae? ?iaeea?aeoaeueii i?ioyaii 5 ae?a, c
iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a, ie??i o?cieaaai?cieo, yeee aaiaeeee
aioo??oiueii’yciai o ??cieo iine?aeiaiinoyo, ?ioiinoeioeyoi?
canoiniaoaaee i?ioyaii 14 ae?a ?acii c aioaaeuei?ioeeii.

Ioe?ieo aoaeoeaiino? canoinoaaiiy ??cieo noai aeaaaeuei?ioecaoe??
i?iaiaeeee ia iniia? ee?i?/ieo iciae, aaeuei?ioieii?ineii?/ieo
aeine?aeaeaiue ? iaea?aeaiiai i?e?inoo iane o?ea.

Iaoaiaoe/ii-noaoenoe/io ia?iaeo ?acoeueoao?a i?iaiaeeee ia eiii’thoa??
?AI ?N ? ioe?ieo a??ia?aeiino? iieaciee?a aecia/aee ca oaaeeoeath
O-e?eoa???a Nouethaeaioa.

?ACOEUeOAOE AeINE?AeAEAIUe

Aieea anea?eicii? ?iaac?? ia aeieeiaiiy iiaaiii?e o naeiae. A?aeiii, ui
ai?ciioe/ia neooaoe?y uiaei iiaaiii?e o naeiae a ainiiaea?noaao,
iaaeaaiiieo/ieo ii anea?eico, ?ai?oa iaeaea ia aea/aeanue. Iaie aia?oa
i?iaiaeeeanue oaea ?iaioa ii aecia/aiith ?iciianthaeaeaiiy iiaaiii?e a
ainiiaea?noaao ??ciiai oeio e?ninoaiiai? ciie Oe?a?ie. I?iaaaeai?
aeine?aeaeaiiy iieacaee, ui iiaaiii?? o ii?inyo cyaeyeeny ia 21–30 aeiao
i?ney ia?iaeaeaiiy ? iaee aino?ee ia?aa?a caoai?thaaiiy. Ianiaee i?iya
iiaaiii?e c i?aeaino?ei oa o?ii?/iei ia?aa?aii ?a?no?oaaee ia 7–10 aeiao
c ii/aoeo a?aeeo/aiiy ii?inyo, oiaoi a 67–70-aeaiiiio a?oe?. Iaeaeuee
a?aenioie caoai?thaaiino? niinoa??aaany o a?oi? oaa?ei 2–4-i?ny/iiai
a?eo (28,5–36,5%). Oaa?eie ia a?aeaiae?ae? iiaaiii??th oai??ee ??aeei
(0,7–3,5%). Na?aae naeiiiaoie ? o?ye?a ee?i?/ii oai?eo ia iiaaiii?th
i?aeoe/ii ia ?a?no?oaaee.

Aiane?aeie i?iaaaeaieo aeine?aeaeaiue iaie aeyaeaii i?yiee aca?iica’ycie
i?ae aenoaineai?noth anea?eicii? ?iaac?? ? /anoioith caoai?thaaiiy
naeiae iiaaiii?yie, yea aoea ??ciith a caeaaeiino? a?ae naciio ?ieo ? ia
caeaaeaea a?ae oeio niaoe?ae?caoe?? ainiiaea?noa. Oae, iaea?eueoee
??aaiue aenoaineaiino? ?iaac?? ?a?no?oaaee o ii?inyo 2–4-i?ny/iiai a?eo
ainaie (a?ae 65 aei 100%); aceieo (a?ae 30 aei 88%); ae?oeo (a?ae 29 aei
90%). A oe? ia??iaee ?ieo niinoa??aaee ca?eueoaiiy caoai?thaaiino?
oaa?ei iiaaiii?yie: ainaie – 10,3–28,5%, aceieo – 6,2–36,5%, ae?oeo –
0,9–19,4%.

O ii?inyo-nenoi?a c?inoaiiy ??aiy caoai?thaaiiy aoei iia’ycaia c
iayai?noth ee/eiie A. suum o eaaaiyo. Iaea?eueoee ??aaiue
caoai?thaaiino? niinoa??aaany a in?ii?e ia??iae (a?ae 5,9 aei 8,1%) ?
aceieo (a?ae 2,2 aei 12,2%), eiee ? ?a?no?oaaee iaea?eueoee a?aenioie
oaa?ei, a eaaaiyo yeeo ciaoiaeeee ee/eiie A. suum (ainaie – a?ae 50,9
aei 64,8%, aceieo – a?ae 23,3 aei 62,2%).

Ioaea, ye iieacaee ?acoeueoaoe aeine?aeaeaiue, niaeao iiaaiii?e ainaie
iia’ycaiee c noai?aiiyi iaea?eueo ni?eyoeeaeo oiia aeey ?icaeoeo y?oeue
A. suum, a a ceiiaee ia??iae iaoiiaeaiee iayai?noth iino?eiiai aeaea?aea
?iaac?? o i?ei?uaiiyo.

?acoeueoaoe aaeuei?ioiey?aineii?/ieo ? aaeoa??ieia?/ieo aeine?aeaeaiue
eaaaiue o oai?eo ia iiaaiii?th ii?inyo o noaoe?iia?ii iaaeaaiiieo/ieo
uiaei anea?eico ainiiaea?noa. A ianoaaeaieo ainiiaea?noaao,
iaaeaaiiieo/ieo uiaei anea?eico, i?e i?iaaaeaii? aeine?aeaeaiue
iaoieia?/iiai iaoa??aeo a?ae ii?inyo c ee?i?/ieie iciaeaie iiaaiii?? o
a?oe? a?ae 2 oeaei?a aei 8 i?nyoe?a iaea?eueoa e?euee?noue ee/eiie o
64,2 aei 83,3% aeiaaee?a aeae?eaia c eaaaiue o oaa?ei aei 3-i?ny/iiai
a?eo. I?e aaeoa??ieia?/iiio aeine?aeaeaii? eaaai?a aeae?eeee 8 aeae?a
aaeoa??e: S. aureus – 40,3%; E. coli – 21,5%; S. albus – 13,3%; S.
pneumoniae – 13,1%; P. vulgaris – 13,1%,; S. choleraesuis – 12,2%; P.
multocida – 10,6%; S. pyogenes – 6,9%. Iaie oaeiae iaeii/anii
i?iaiaeeeeny aen?ae c eaaai?a a?ae caei?iaeo oaa?ei (12 i?ia). ?c ieo o
2 (16,6%) aeae?eaii eoeueoo?o S. aureus ? o 1 (8,3%) – P. vulgaris. I?e
aecia/aii? /ooeeaino? aei aioea?ioee?a aeae?eaieo eoeueoo? iaea?eueoo
ciio cao?eiee ?inoo coiiaethaaee “Eeaiienee” (27 ii), “Aaeo?ee” (25 ii),
no?aioii?oeei (20 ii), ienaoeee?i ? aii?oeee?i (15 ii).

A ca’yceo c oei, ui o oai?eo ia iiaaiii?th ii?inyo, ?c caaaeueii?
e?eueeino? aeae?eaieo aeae?a aaeoa??e a?eueoa anueiai neeaaeaee S.
aureus ? E. coli, aiie a iiaeaeueoiio aoee aeei?enoai? aeey
aenia?eiaioaeueiiai a?aeoai?aiiy iiaaiii?e.

Aenia?eiaioaeueia a?aeoai?aiiy anioe?aoeaieo iiaaiii?e o ii?inyo a
eaai?aoi?ieo oiiaao. Ee?i?/i? oa iaoieiai-aiaoii?/i? ci?ie. Io?eiai?
?acoeueoaoe aenia?eiaioaeueieo aeine?aeaeaiue na?ae/aoue i?i oa, ui
ca?aaeaiiy ii?inyo ?iaac?eieie yeoeyie A. suum aeeeeeaei iiaaiii?th a
on?o aeine?aeieo oaa?ei, eoeueoo?ith cieioenoiai noao?eieieo – a 25%
oaa?ei, a eoeueoo?ith eeoeiai? iaee/ee – ia i?ecaiaeeei aei ?icaeoeo
caoai?thaaiiy. Anioe?aoeaia ca?aaeaiiy ii?inyo cacia/aieie eoeueoo?aie
noi?iaiaeaeoaaeinue ?icaeoeii iiaaiii?? a on?o 8 oaa?ei ?
oa?aeoa?ecoaaeiny a?eueo oyaeeei ia?aa?aii caoai?thaaiiy. Ne?ae oaeiae
cacia/eoe, ui ca?aaeaiiy oaa?ei ?iaac?eieie yeoeyie A. suum
noi?iaiaeaeoaaeinue ?icaeoeii eaoa?aeueii? a?iioiiiaaiii??, eoeueoo?ith
cieioenoiai noao?eieieo – aenoaeaoeaii? na?icii? iiaaiii?? c neaaeei
aaii?aa?/iei i?iyaii. Anioe?aoeaia ca?aaeaiiy noi?iaiaeaeoaaeinue
nii/aoeo ?icaeoeii eaoa?aeueii?, a iio?i ai?eii-eaoa?aeueii?
ae??aiiaiaieuaai? iiaaiii??.

Aaiaoieia?/i? oa ?ioiieia?/i? iieacieee. A ?acoeueoao?
i?iaaaeaieoaeine?aeaeaiue anoaiiaeaii, ui ey?aaeueiee anea?eic
noi?iaiaeaeoaaany a?eo?iiai??th c 5 ii 20-oo aeiao aeine?aeo (a
na?aaeiueiio ia 29,4%), eaeeioeeoicii (a na?aaeiueiio ia 97,7%) ?
ca?eueoaiiyi e?eueeino? aiceiio?e?a i?ioyaii ia??iaeo niinoa?aaeaiiy (a
na?aaeiueiio ia 59,5%) o ii??aiyii? c eiio?ieai. Ui noino?oueny
O-e?ioioeeo?a, oi oa?aeoa? ?o ci?i oa?aeoa?ecoaaany a??ia?aeiei
ca?eueoaiiyi caaaeueieo O-e?ioioeeo?a ia 5 ? 12-oo aeiao aeine?aeo ia
13,8 ? 28,6%, oaio?e?i?acenoaioieo – 19,2 ? 50,7% ? A-e?ioioeeo?a c 12
ii 45-oo aeiao ia 48,6, 75,1, 20,1 ? 13,5% o ii??aiyii? c iieacieeaie
eiio?ieueieo oaa?ei. Ia 20 ? 36-oo aeiao aeine?aeo a?aecia/aeiny
ciaioaiiy e?eueeino? caaaeueieo O-e?ioioeeo?a, a?aeiia?aeii ia 18,4 ?
12,6% ? ca?eueoaiiy oaio?e?i/ooeeaeo O-e?ioioeeo?a, a?aeiia?aeii ia 45,4
? 16,6% o ii??aiyii? c eiio?ieai.

O ?iaaciaaieo ii?inyo aoea anoaiiaeaia oaiaeaioe?y aei ciaioaiiy
caaaeueiiai a?eeo ia i?ioyc? aeine?aeo (c 5 ii 45-oo aeiao), a
na?aaeiueiio ia 10,4%; iaeiie/aiiy ?ioiiaeiaoe?i?a eeano I aei 12-?
aeiae niinoa?aaeaiiy (2,140,19 ia/ie, p<0,05) o ii??aiyii? c eiio?ieai (1,410,17 ia/ie) ? a??ia?aeia ca?eueoaiiy ??aiy ?ioiiaeiaoe?i?a G c 20 ii 45-oo aeiao – c 24,520,22 aei 18,910,23 ia/ie i?ioe eiio?ieth 15,010,36–15,150,31 ia/ie; aenieee ai?no oee?eoethth/eo ?ioiieo eiiieaen?a – a?ae 0,190,02 aei 0,250,06 ia/ie i?ioe eiio?ieth 0,080,03–0,100,02 ia/ie (?<0,01–0,001). Anioe?aoeaia ca?aaeaiiy ii?inyo ?iaac?eieie yeoeyie A. suum oa eoeueoo?aie S. aureus ? A. noli (3 aeine?aeia a?oia) i?ecaiaeeei aei ciaioaiiy e?eueeino? a?eo?ioeeo?a ia i?ioyc? anueiai ia??iaeo aeine?aeo (c 5 ii 45-oo aeiao) ia 37,9, 39,9, 40,5, 38,4 oa 35,4% a ii??aiyii? c eiio?ieai. O oaa?ei o?aouei? aeine?aeii? a?oie a?aecia/aee ca?eueoaiiy e?eueeino? eaeeioeeo?a c 19,510,81 aei 35,300,56109/e c 5 ii 45-oo aeiao aeine?aeo o ii??aiyii? c iieacieeaie eiio?ieueieo oaa?ei – 12,010,52–12,51109/e. Aiae?c ?acoeueoao?a ai?noo aiceiio?e?a na?ae/eoue i?i oa, ui o ca?aaeaieo ii?inyo c 5 ii 12-oo aeiao aeine?aeaeaiiy ?a?no?oaaee ca?eueoaiiy e?eueeino? aiceiio?e?a (7,60,20% oa 9,30,29%), a ia 20-oo aeiao ?o e?euee?noue a??ia?aeii ciaiooaaeanue aei 1,30,22% ? ia e?iaoeue aeine?aeo ai?no aiceiio?e?a aoa ia 50,0 ? 27,3% ieae/ei, o ii??aiyii? c iieacieeaie eiio?ieueieo oaa?ei. Anioe?aoeaia ca?aaeaiiy i?ecaiaeeei aei a??ia?aeiiai ciaioaiiy ia i?ioyc? aeine?aeo A-?OE ee?oei a ii??aiyii? c eiio?ieai ia 14,8, 22,5, 35,3, 38,1, 33,6%, ciaioaiiy ??aiy oaio?e?i?acenoaioieo O-e?ioioeeo?a a oeae ia??iae, iniaeeai ia 20 ? 36-oo aeiao – 9,30,64; 8,10,47% a?aeiinii iieaciee?a eiio?ieth (25,70,70 oa 23,20,63%), c?inoaiiy e?eueeino? oaio?e?i/ooeeaeo O-e?ioioeeo?a a?aeiinii iieaciee?a eiio?ieueieo oaa?ei ia 1, 12, 20 ? 36-oo aeiao aeine?aeo, a?aeiia?aeii ia 60,8, 51,2, 19,4, 30,4%. I?e aeine?aeaeaii? aeeiai?ee A-e?ioioeeo?a niinoa??aaee cieaeaiiy ?o ai?noo ia i?ioyc? aeine?aeo o ii??aiyii? c eiio?ieai ia 20,0, 29,1, 58,8, 42,3, 33,0%. A??ia?aeio ??cieoeth i?e oeueiio a?aecia/aee ia 5, 12, 20 ? 45-oo aeiao aeine?aeo. E??i oeueiai, a?aei?/aeinue ciaioaiiy caaaeueiiai a?eea ia 5-oo aeiao aeine?aeo (52,23,80 a/e) a?aeiinii iieacieea eiio?ieueieo oaa?ei (56,02,66 a/e). O ianooii? aei? aeine?aeo a?aeaoaaeinue i?aeaeuaiiy ??aiy caaaeueiiai a?eea, c a??ia?aeiith ??cieoeath ia 20 ? 36-oo aeiao – 88,45,00 a/e ? 83,84,30 a/e a ii??aiyii? c iieacieeaie eiio?ieueieo oaa?ei (60,71,87 ? 66,84,02 a/e). Ai?no ?ioiiaeiaoe?i?a eeano I o ii?inyo o?aouei? aeine?aeii? a?oie aoa a??ia?aeii aenieei ia 5, 12, 20-oo aeiao aeine?aeo a?aeiinii eiio?ieth ia 32,6, 76,8, 43,5%, a e?euee?noue aioeo?e IgG ciaoiaeeeanue ia aenieiio ??ai? ia i?ioyc? aeine?aeo (19,100,76–20,401,01%). Aeine?aeaeaiiyie ne?iaaoee e?ia? ca?aaeaieo ii?inyo anoaiiaeaii a??ia?aeii aenieee ??aaiue Oe?E ia 5, 20, 36 oa 45-oo aeiao (0,380,04, 0,470,04, 0,420,03, 0,230,02 ia/ie) i?ioe eiio?ieth (0,110,01, 0,120,01, 0,100,02, 0,120,02 ia/ie). Oaeei /eiii, ?c i?eaaaeaieo aeaieo aeaeii, ui anioe?aoeaia ca?aaeaiiy ii?inyo ?iaac?eieie yeoeyie A. suum oa eoeueoo?aie S. aureus ? E. coli noi?iaiaeaeoaaeinue no?eeith a?eo?iiai??th, ae?aaeaiei eaeeioeeoicii, ca?eueoaiiyi e?eueeino? aiceiio?e?a o ia?oee oeaeaeaiue i?ney ca?aaeaiiy ? ciaioaiiyi ?o c 20 ii 45-oo aeiao aeine?aeaeaiiy; i?ecaiaeeei aei i?eai?/aiiy ee?oeiiiai ? aoii?aeueiiai oaeoi??a ?ioi?oaoo oaa?ei, ui ae?aaeaeiny a ciaioaii? ai?noo O- ? A-e?ioioeeo?a i?ioyaii aeine?aeo; cieaeaiiyi ??aiy caaaeueiiai a?eea o ia?o? aei? i?ney ca?aaeaiiy, c iine?aeoth/ei i?aeaeuaiiyi eiai aei e?ioey aeine?aeo, i?aeaeuaiiyi ??aiy IgM ia 5, 12 oa 20-oo aeiao niinoa?aaeaiiy oa IgG ia i?ioyc? ia??iaeo aeine?aeaeaiue (45 ae?a) ? aenieei ai?noii Oe?E c 5 ii 45-oo aeiao aeine?aeo. Ana oea na?ae/eoue i?i ia?aeiiee aieea ee/eiie A. suum i?ae /an ?o i?a?aoe?? ia ?ioiiee noaoon oaa?ei ? ?icaeoie iiaaiii??, c iine?aeoth/ei oneeaaeiaiiyi ia?aa?ao i?ioeano, aeeeeeaiiai ae??th ??cieo i?e?ii?aai?ci?a. Oa?ai?y anioe?aoeaieo iiaaiii?e o naeiae a ainiiaea?noaao, iaaeaaiiieo/ieo ii anea?eico. E?eoaaiiy ii?inyo, oai?eo ia iiaaiii?th, nii/aoeo i?iaiaeeee a aenia?eiaioaeueiiio aeine?ae? a oiiaao o/ainio “1 O?aaiy”. Anueiai aoei aeei?enoaii 87 aie?a ii?inyo 30–40-aeaiiiai a?eo. ?acoeueoaoe oeueiai aeine?aeo i?aaenoaaeai? o oaaeeoe? 1. A ?acoeueoao? canoinoaaiiy ??cieo i?aia?ao?a anoaiiaeaii, ui iaea?eueo aoaeoeaieie aeyaeeenue eiiieaeni? e?eoaaeueii-i?io?eaeoe/i? caoiaee c aeei?enoaiiyi aioaaeuei?ioee?a c aioea?ioeeaie: iaiaeo?o c “Eeaiieneeii”, aeaeoiiaeno c “Eeaiieneeii”, o?cieaaai?cieo c “Aaeo?eeii” (aoaeoeai?noue canoinoaaiiy a oeeo a?oiao neeaaeaea a?ae 75 aei 100%). I?e canoinoaaii? o?eueee iaeieo aioaaeuei?ioee?a e?eoaaeueia aoaeoeai?noue ?o aoea a iaaeao 40,0–57,1%. Ne?ae cacia/eoe, ui i?e e?eoaaii? o?eueee aioea?ioeeaie oai?eo ia iiaaiii?th ii?inyo, aoaeoeai?noue ?o canoinoaaiiy neeaaeaea 12,5–22,2%, a ee/eiee A. suum aoee aeyaeai? o 35,7% oaa?ei. I?e iiaeaeueoiio ii??aiyii? eiiieaenieo e?eoaaeueii-i?io?eaeoe/ieo noai iaee?au? ?acoeueoaoe ii e?eoaaiith ii?inyo aoee io?eiai? i?e canoinoaaii? o?cieaaai?cieo c “Aaeo?eeii”. O?cieaaai?cie, yeee ye a?aeiii aiaeii/an aieiae?? aioaaeuei?ioieie oa ?ioiiiiaeoethth/eie aeanoeainoy-ie, ni?eya i?aeaeuaiith ?ioiia?ieia?/iiai noaio i?aai?cio oaa?ei, ui noi?iaiaeaeoaaeiny ciaioaiiyi ??aiy Oe?E (0,140,03–0,100,01 ia/ie). Eiiieaenia canoinoaaiiy i?aia?ao?a caaacia/oaaei a?aeiiaeaiiy e?eueeino? O- ? A-e?ioioeeo?a, ui ae?aaeaeiny o i?aeaeuaii? oeeo iieaciee?a i?ney e?eoaaiiy: O-e?ioioeeo?a a?aeiia?aeii c 22,70,35 aei 41,40,67% o ii??aiyii? c oaa?eiaie eiio?ieueii? a?oie 33,50,37–23,60,19%, A-e?ioioeeo?a a?aeiia?aeii 19,60,13–24,40,42% ? 27,30,32–130,15%. Oaaeeoey 1 Aoaeoeai?noue canoinoaaiiy i?aia?ao?a aeey e?eoaaiiy ii?inyo,oai?eo ia iiaaiii?th I?aia?aoeE?euee?noue oai?eo oaa?ei, aie?aCaoai?thaai?noue, %Aoaeoeai?noue, %ia ii/aoie aeine?aeoia e?iaoeue aeine?aeoCaaeio-eiia ii/aoie aeine?aeoia e?iaoeue aeine?aeoAioaaeuei?ioeee1. Iaiaeo?53—10060402. Aeaeoiiaen94—10044,455,63. O?cieaaai?cie73—10042,957,1Aioea?ioeee4. “Eeaiienee”107110077,822,25. “Aaeo?ee”107210087,512,5Aioaaeuei?ioeee + Aioea?ioeee6. Iaiaeo?+ “Eeaiienee”92—10022,277.87. Aeaeoiiaen+ “Eeaiienee”123—10025758. O?cieaaai?cie+ “Aaeo?ee”8——100—100 Eiio?ieue 21173—87,5—C iaoith i?iaaaeaiiy oe?ieiai aei?iaoaaiiy aoaeoeaiino? canoinoaaiiy oeeo i?aia?ao?a, iaie aoa i?iaaaeaiee ae?iaie/ee aeine?ae a AO “?iaeono??aeueiee” ii e?eoaaiith ii?inyo, oai?eo ia iiaaiii?th. Anueiai aoei aeei?enoaii 96 aie?a ii?inyo 30–40-aeaiiiai a?eo. Aeine?ae aoei i?iaaaeaii o 2 aoaie. Ia?oee aeeth/aa ia?iaeo ii?inyo aioaaeuei?ioeeaie, ae?oaee – eiiieaenio oa?ai?th c aeei?enoaiiyi aioaaeuei?ioee?a c aioea?ioeeaie, aioaaeuei?ioeea c ?ioiinoeioeyoi?ii ? aioaaeuei?ioeea ?acii c aioea?ioeeii oa ?ioiinoeioeyoi?ii. C aioaaeuei?ioee?a canoiniaoaaee oao?ai?cie, oethaaiie 5%, iaiaeo?, ye? caaeaaaee a?oiiaei iaoiaeii c eiioeaio?iaaieie ei?iaie, iiae??aiaieie aeicaie i?ioyaii 5 ae?a c iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a, ie??i o?cieaaai?cieo, yeee aaiaeeee aioo??oiueii'yciai, iaeii?aciai. ?ioiinoeioeyoi? (iaoeeo?aoeee) aeei?enoiaoaaee ai?iaeiaae 14 ae?a. Aioea?ioee (“Eeaiienee”) – o ?aeiiaiaeiaai?e a ianoaiia? aeic? (15 ie/150 ea iane o?ea), aea c iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a. An? cai?iiiiiaai? iaie eiiieaeni? noaie e?eoaaiiy (oao?ai?cieo c “Eeaiieneeii”, o?cieaaai?cieo c “Eeaiieneeii” ? oethaaiieo 5% c “Eeaiieneeii” ? iaoeeo?aoeeeii) iaee aenieo (100%) oa?aiaaoe/io ae?th. A oie aea /an, canoinoaaiiy eiaeiiai i?aia?aoo ie?aii cia/ii cieaeoaaei aoaeoeai?noue. Cie?aia, i?e aeei?enoaii? aioaaeuei?ioee?a aiia neeaaeaea a?ae 16,6 aei 40,0%, iaoeeo?aoeeeo – 11,1%, “Eeaiieneeo” – 14,7%. Iniaeeai ne?ae a?aecia/eoe oa, ui canoinoaaiiy eiiieaenieo noai e?eoaaiiy iiia?aaeaeoaaei iiaoi?ia ?a?iaacoaaiiy oaa?ei anea?enaie ia i?ioyc? 1,5–2-o i?nyoe?a. Ca ia??iae niinoa?aaeaiiy (2 i?nyoe?) na?aaei?e i?e??no iane o?ea ii?inyo o a?oiao, aea canoiniaoaaee eiiieaeni? noaie e?eoaaiiy aoa aeuei, a na?aaeiueiio o 2 ?ace, o ii??aiyii? c eiio?ieai. Aea/aiiy aoaeoeaiino? canoinoaaiiy i?a?iaa?iaeueii? aeaaaeuei?ioecaoe?? oa ?ioiinoeioethth/eo cania?a aeey i?io?eaeoeee iiaaiii?e, aeeeeeaieo anea?eiciith ?iaac??th, o ae?iaie/eo oiiaao. Iaie oaeiae i?iaiaeeeanue i?a?iaa?iaeueia aeaaaeuei?ioecaoe?y ?c canoinoaaiiyi ??cieo i?aia?ao?a. Aeine?ae i?iaiaeeee a 2 aoaie. O ia?oiio cae?enithaaee ia?iaeo ii?inyo, ii/eiath/e c 14–15-aeaiiiai a?eo (107 aie?a), a o ae?oaiio – c 30–35-aeaiiiai a?eo (100 aie?a). Ii?inyo oo?eioaaee ?acii ?c naeiiiaoeaie, ye? aoee an? o?aaeai? anea?enaie. Aeey ia?iaee aeine?aeieo oaa?ei aeei?enoiaoaaee aioaaeuei?ioeee oe?ieiai niaeo?o ae??: oao?ai?cie, oethaaiie 5%, iaiaeo?, o?cieaaai?cie oa ?ioiinoeioeyoi? – iaoeeo?aoeee. Aioaaeuei?ioeee caaeaaaee c eiioeaio?iaaieie ei?iaie, a?oiiaei iaoiaeii, i?ioyaii 5 ae?a c iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a ca aeiyoeii o?cieaaai?cieo, yeee aaiaeeee o ??cieo iine?aeiaiinoyo (o?e?aciai c ?ioa?aaeii 15 ae?a, iaeii?aciai c iiaoi?iei aaaaeaiiyi /a?ac iaeei i?nyoeue). Aoaeoeai?noue i?iaaaeaieo caoiae?a ioe?ithaaee ia iniia? ee?i?/ieo ianoaaeaiue, eii?ineii?/ieo aeine?aeaeaiue ? na?aaeiueiaeiaiaeo i?e?ino?a iane o?ea ia i?ioyc? 90 ae?a. A ?acoeueoao? anoaiiaeaii, ui iaea?eueo aoaeoeaiei ? canoinoaaiiy i?a?iaa?iaeueii? aeaaaeuei?ioecaoe??, ii/eiath/e c 14–15-aeaiiiai a?eo. Iaee?aua i?io?eaeoe/ia aoaeoeai?noue (a?aenooi?noue ii?inyo c ee?i?/ieie iciaeaie iiaaiii??, caa?aaeai?noue) io?eiaia i?e aeei?enoaii? oao?ai?cieo, o?cieaaai?cieo oa oethaaiieo 5% c iaoeeo?aoeeeii. Canoinoaaiiy oeeo noai caiia?aaei ca?aaeaiith naeiae anea?enaie ia i?ioyc? 2–3 i?nyoe?a, a na?aaeiueiaeiaia? i?e?inoe iane o?ea aoee a??ia?aeii aeueie o ii??aiyii? c eiio?ieai: 201,3, 220,3, 205,0 oa 181,0 a, a?aeiia?aeii. Ne?ae a?aecia/eoe, ui iaea?eueo aenieo i?io?eaeoe/io ae?th aeyaea o?cieaaai?cie i?e o?e?aciaiio aaaaeaii? ii?inyoai 14–15-aeaiiiai ? iaeiii?ny/iiai a?eo c ?ioa?aaeii 15 ae?a. Ioaea, aeey i?io?eaeoeee aeieeiaiiy anea?eicii? iiaaiii?? i?a?iaa?iaeueio aeaaaeuei?ioecaoe?th ne?ae ii/eiaoe c 14–15-aeaiiiai a?eo c aeei?enoaiiyi oaeeo noai, ye? aeeth/athoue: — o?cieaaai?cie, aioo??oiueii'yciai o aeic? 0,6 ie/10 ea iane o?ea, o?e?aciai c ?ioa?aaeii 15 ae?a; — oethaaiie 5%, c ei?iii o aeic? 1 ia/ea Ae? 5 ae?a i?ae?yae o eiiieaen? c iaoeeo?aoeeeii, a aeic? 50 ia/ea i?ioyaii 14 ae?a; — oao?ai?cie, aioo??oiuei, o aeic? 2 ia/ea Ae? 5 ae?a i?ae?yae c iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a. Canoinoaaiiy oeeo noai iiia?aaeaeoaaei ca?aaeaiiy oaa?ei anea?enaie ia i?ioyc? 2–3 i?nyoe?a, ni?eyei ca?eueoaiith na?aaeiueiaeiaiaeo i?e?ino?a iane o?ea, caaaeyee i?aeaeuaiith ?ioiia?ieia?/iiai noaio i?aai?cio. I?e iaiao?aeiino? c iaeiii?ny/iiai a?eo iiaeia oaeiae canoiniaoaaoe oae? noaie i?a?iaa?iaeueii? aeaaaeuei?ioecaoe??, ye? aeeth/athoue: — o?cieaaai?cie, aioo??oiueii'yciai, o aeic? 0,6 ie/10 ea iane o?ea iaeii?aciai c iiaoi?iei aaaaeaiiyi /a?ac 1 i?nyoeue; — o?cieaaai?cie, aioo??oiueii'yciai, o aeic? 0,6 ie/10 ea iane o?ea o?e?aciai c ?ioa?aaeii 15 ae?a; — oethaaiie 5%, aioo??oiuei o aeic? 1 ia/ea Ae? 5 ae?a i?ae?yae a eiiieaen? c iaoeeo?aoeeeii o aeic? 50 ia/ea i?ioyaii 14 ae?a. AENIIAEE 1. A ainiiaea?noaao ??ciiai oeio e?ninoaiiai? ciie Oe?a?ie na?aae naeiae oe?iei ?iciianthaeaeai? iiaaiii??, ni?e/eiai? anea?eni-i?e?iaiith anioe?aoe??th, ui i?ecaiaeyoue aei cia/ieo iaoieia?/ieo ci?i o i?aai?ci? o?aaeaieo oaa?ei, caaaeathoue aaeeeeo aeiiii?/ieo caeoe?a naeia?noao, ye? neeaaeathoueny ?c caaeaae? naeiae, cieaeaiiy i?e?ino?a iane o?ea, iia??oaiiy yeino? i?iaeoeoe?? oa ?i. 2. ?ieue i?a?oth/eo ee/eiie A. suum ? i?e?ii?aai?ci?a o aeieeiaii? iiaaiii?? naeiae aea/aia oeyoii i?iaaaeaiiy eiiieaenieo aeine?aeaeaiue c aeei?enoaiiyi ee?i?/ieo, iaoieiai-aiaoii?/ieo, aaiaoieia?/ieo, i?e?ia?ieia?/ieo, a?io?i?/ieo, ?ioiieia?/ieo iaoiae?a aeine?aeaeaiue. ?ic?iaea eiiieaenieo caoiae?a i?io?eaeoeee ? e?eoaaiiy caiaeaiiy eaaai?a o oaa?ei cae?eniaii ca aeiiiiiaith aeeth/aiiy a noaie canoinoaaiiy iiaeo aoaeoeaieo aioaaeuei?ioee?a ? aioea?ioee?a oe?ieiai niaeo?o ae??, a oaeiae ?ioiinoeioeyoi?a. 3. A ianoaaeaieo naeia?nueeeo ainiiaea?noaao, noaoe?iia?ii iaaeaaiiieo/ieo uiaei anea?eico, iiaaiii?? ?a?no?othoueny o aeaeyae? anioe?aoeaiiai caoai?thaaiiy, aea ia?aeiiei oaeoi?ii o eiai aeieeiaii? yaeythoueny ee/eiee A. suum, a oneeaaeithth/o ?ieue a?ae?a?athoue ??ci? aeaee aaeoa??e (S. aureus, E. coli, P. vulgaris, S. albus, P. multocida oa ?i.). I?e aaeuei?ioiea?aineii?/iiio aeine?aeaeaii? eaaaiue o oai?eo ia iiaaiii?th ii?inyo, ee/eiee A. suum anoaiiaeai? o 64,2–83,3% aeiaaee?a. O a?eueoino? aeine?aeaeaieo i?ia ?acii c ee/eieaie anea?en?a aeae?eyee oaeiae S. aureus (40,3%), E. coli (21,5%), S. albus (13,3%), P. vulgaris (13,1%). 4. A ainiiaea?noaao, iaaeaaiiieo/ieo uiaei anea?eico naeiae, iiaaiii?? o ii?inyo-nenoi?a aeyaeai? c 21–30 aeiae i?ney ia?iaeaeaiiy, a ianiaee i?iya caoai?thaaiiy ?o ?a?no?o?oueny ia 7–10 aeiao c ii/aoeo a?aeeo/aiiy ii?inyo, oiaoi a 67–70-aeaiiiio a?oe?. Caoai?thaai?noue ii?inyo o 2–4-i?ny/iiio a?oe? a cia/i?e i??? iaoiiaeaia oaoiieia??th oo?eiaiiy oaa?ei, naciiii ?ieo ? nooiaiai eiioai?iaoe?? i?noeue ?icoaooaaiiyi oaa?ei ?iaac?eieie aeaiaioaie. 5. C??no aenoaineaiino? anea?eicii? ?iaac?? o ii?inyo 2–4-i?ny/iiai a?eo i?ecaiaeeoue aei ca?eueoaiiy oai?eo ia iiaaiii?th oaa?ei, a o ii?inyo-nenoi?a – aei c?inoaiiy ??aiy caoai?thaaiino? ? ia? ca'ycie c aenoaineai?noth ? ?ioaineai?noth ?iaacoaaiiy ee/eieaie anea?en?a. 6. Aenia?eiaioaeueia ca?aaeaiiy ii?inyo ?iaac?eieie yeoeyie A. suum aeeeeeaei iiaaiii?th o an?o aeine?aeieo oaa?ei, yea i?iyaeyeanue a?eo?iiai??th c 5 ii 20-oo aeiao, eaeeioeeoicii, ca?eueoaiiyi e?eueeino? aiceiio?e?a, i?aeaeuaiiyi O-e?ioioeeo?a ia 5 ? 12-oo aeiao i?ney ca?aaeaiiy, a A-e?ioioeeo?a – c 12 ii 36-oo aeiao. C 20 ii 36-oo aeiao ianooiaei ciaioaiiy e?eueeino? O-e?ioioeeo?a, a na?aaeiueiio ia 15,4%. I?e ca?aaeaii? ii?inyo o?eueee eoeueoo?ith cieioenoiai noao?eieieo iiaaiii?y ?icaeaaeany o 25% oaa?ei, a aaaaeaiiy ?i eoeueoo?e eeoeiai? iaee/ee ia aeeeeeaei iaoieia?/ieo ci?i a i?aai?ci?. 7. Iaeii/ania ca?aaeaiiy ii?inyo yeoeyie A. suum oa eoeueoo?aie cieioenoiai noao?eieieo ? eeoeiai? iaee/ee aeeeeeaei caiaeaiiy eaaaiue o an?o aeine?aeieo oaa?ei, yea oa?aeoa?ecoaaeiny oyaeeei ia?aa?aii: nii/aoeo ?icaeoeii eaoa?aeueii?, a iio?i ai?eii-eaoa?aeueii? iiaaiii??, no?eeith a?eo?iiai??th, ae?aaeaiei eaeeioeeoicii ia i?ioyc? aeine?aeo, ca?eueoaiiy e?eueeino? aiceiio?e?a o ia?oee oeaeaeaiue i?ney ca?aaeaiiy, a i?ci?oa, ii/eiath/e c 20 ii 45-oo aeiao aeine?aeaeaiue, ciaioaiiyi ?o e?eueeino?, noi?an??th O-e?ioioeeo?a ai?iaeiaae ia??iaeo aeine?aeaeaiiy oa aenieei ai?noii oee?eoethth/eo ?ioiieo eiiieaen?a. 8. I?e e?eoaaii? ii?inyo, oai?eo ia iiaaiii?th, iaea?eueo aoaeoeaiei aeyaeeinue eiiieaenia canoinoaaiiy i?aia?ao?a: aioaaeuei?ioee?a c aioea?ioeeaie (o?cieaaai?cieo c “Aaeo?eeii”, oao?ai?cieo c “Eeaiieneeii”) ? aioaaeuei?ioeea c aioea?ioeeii oa ?ioiinoeioeyoi?ii (oethaaiieo 5% c “Eeaiieneeii” oa iaoeeo?aoeeeii). Canoinoaaiiy ?o ni?eyei cieaeaiith caoai?thaaiino? ? oaeaeeiio iaeoaeaiith, ui iiia?aaeaeoaaei caaeaae? oaa?ei, i?aeaeuoaaei na?aaeiueiaeiaia? i?e?inoe iane o?ea ? i?io?eaeooaaei i?ney oeueiai ca?aaeaiiy naeiae anea?enaie i?ioyaii 2-o i?nyoe?a. 9. Aeei?enoaiiy eiiieaenieo noai e?eoaaiiy i?ecaiaeeei aei iaeoaeaiiy oaa?ei ? caaacia/oaaei ii?iae?caoe?th a ?o i?aai?ci? e?eueeino? a?eo?ioeeo?a, eaeeioeeo?a, ai?noo caaaeueiiai a?eea, ciaioaiiy ??aiy oee?eoethth/eo ?ioiieo eiiieaen?a, a?aeiiaeaiiy iieaciee?a O- ? A-e?ioioeeo?a aeecueei aei ii?ie. 10. Aeey i?io?eaeoeee iiyae iiaaiii?e o ii?inyo ne?ae i?iaiaeeoe, ii/eiath/e c 14–15-aeaiiiai a?eo, i?a?iaa?iaeuei? aeaaaeuei?ioecaoe??, aeei?enoiaoth/e i?e oeueiio aioaaeuei?ioeee oe?ieiai niaeo?o ae??: o?cieaaai?cie, o?e?aciai c ?ioa?aaeii 15 ae?a oa aioaaeuei?ioeea c ?ioiinoeioeyoi?ii: oethaaiie 5% o aeic? 1 ia/ea 5 ae?a i?ae?yae c iiaoi?iei aaaaeaiiyi /a?ac 14 ae?a ? iaoeeo?aoeee ai?iaeiaae 14 ae?a ?acii c aioaaeuei?ioeeii. Aeei?enoaiiy oeeo i?aia?ao?a i?io?eaeooaaei ca?aaeaiiy oaa?ei anea?enaie i?ioyaii 2,5–3-o i?nyoe?a oa caiia?aaei iiya? iiaaiii?e. ioae?eaoe?? 1. Aaeay E. Ae. Annioeeaoeaiua iiaaiiiee o ii?inyo // Aao. iaaeeoeeia: I?aea?ae. oaiao. iaoe. ca. – E., 1997. – Aei. 73. – N. 51–54. 2. Annioeeaoeaiua aieacie naeiae / A. N. Oaoiaoeia, TH. A. I?eoiaeueei, E. E. Eooeaiei, I. A. Oaiiue, E. Ae. Aaeay // Aao. iaaeeoeeia: I?aea?ae. oaiao. iaoe. ca. – O., 1998. – Aei. 75. – N. 182–194. 3. Aaeay E. Ae. Oniaa?oainoaiaaiea iaoiaeeee eoeueoeae?iaaiey yeoe naeiie anea?eaeu a eaai?aoi?iuo oneiaeyo // Aao. iaaeeoeeia: I?aea?ae. oaiao. iaoe. ca. – O., 1998. – Aei. 74. – N. 278–282. 4. Oaoiaoeia A. N., A?ea ?. Ae. Iniaeeaino? iaoiii?oieia?/ieo ci?i aeayeeo i?aai?a uo??a i?e ey?aaeueiiio anea?eaeic? // A?ni. A?eioea?e?a. aea?ae. aa?a?. oi-oo: Ca. iaoe. i?aoeue. – A?ea Oea?eaa, 1998. – *. 1, Aei 4. – N. 127–130. 5. A?ea ?. Ae. Aieea anea?eaeicii? ?iaac?? ia aeieeiaiiy iiaaiii?e o ii?inyo // A?ni. A?eioea?e?a. aea?ae. aa?a?. oi-oo: Ca. iaoe. i?aoeue. – A?ea Oea?eaa, 1998. – *. 1, Aei 5. – N. 50–53. 6. A?ea ?. Ae. Ee?i?ei-aaiaoieia?/i? iieacieee o ii?inyo i?e aenia?eiaioaeuei?e anea?eaeici?e iiaaiii?? // No/ani? i?iae. aao. iaaeeoeeie, cii?iaeaia??? oa oaoiieia?? i?iaeoeo?a oaa?eiieoeoaa: Ca. iaoa??ae?a I?aeia?. iaoe.-i?aeo. eiio., (Euea?a, 9–11 aeiaoiy 1997 ?.). – Euea?a, 1997. – N. 151–153. 7. A?ea ?. Ae. Iaoieia?/i? ci?ie a i?aaiao oa oeaieiao i?e anea?eici?e ?iaac?? // ?icaeoie aao. iaoee a Oe?a?i?: caeiaooee oa i?iaeaie: Ca. iaoa?. I?aeia?. iaoe.-i?aeo. eiio. (Oa?e?a, 24–26 aa?aniy 1997 ?.). – O., 1997. – N. 67–68. 8. Aaeay E. Ae. Eeeie/aneia oa/aiea yenia?eiaioaeueiiai anea?eaeica o ii?inyo // Iaoe. aeinyaiaiiy a aaeoc? aao. iaaeeoeeie: Iaoa?. I?aeia?. iaoe.-i?aeo. eiio. iieiaeeo a/aieo (Oa?e?a, 1-2 ea?oiy 1997 ?.). – O., 1997. – N. 5. 9. Oaoiaoeia A. N., Aaeay E. Ae. Ia?aceoioeaiic e?aeeo i?e anea?eiciie iiaaiiiee ii?inyo// I?iae. e ia?niaeoeau ia?aceoioeaiieiaee: Iaoa?. V Iaaenuacae. eiio. ia?aceoioeaiieiaia Oe?aeiu (Eoaaine, 29–30 ieoya?y 1997 a.). – O.; Eoaaine, 1997. – N. 179–180. A?ea ?. Ae. Iiaaiii?? naeiae, ni?e/eiai? anea?eni-i?e?iaieie anioe?aoe?yie oa ?ic?iaea i?io?eaeoe/ieo ? e?eoaaeueieo caoiae?a. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa aaoa?eia?ieo iaoe c niaoe?aeueiino? 03.00.18. – ia?aceoieia?y, aaeuei?ioieia?y. ?inoeooo aenia?eiaioaeueii? ? ee?i?/ii? aaoa?eia?ii? iaaeeoeeie OAAI, Oa?e?a, 1999. A aeena?oaoe?? aeeeaaeai? iaoa??aee ii aea/aiith anioe?aoeaieo iiaaiii?e naeiae anea?eni-i?e?iaii? i?e?iaee. Aia?oa aoee iaea?aeai? aeai? i?i ?iciianthaeaeaiiy iiaaiii?e a ainiiaea?noaao ??ciiai oeio, iaaeaaiiieo/ieo uiaei anea?eico naeiae, ? aneia?eiaioaeueii i?aeoaa?aeaeaia aaaeeeaa ?ieue ee/eiie A. suum o aeieeiaii? iiaaiii?e o ii?inyo, oneeaaeiaieo oiiaii-iaoiaaiiith i?e?ioei?ith. Anoaiiaeaiee aca?iica'ycie i?ae aenoaineai?noth anea?eicii? ?iaac?? ? ??aiai caoai?thaaiino? iiaaiii?yie o ii?inyo 2–4-i?ny/iiai a?eo, a oaeiae i?ae aenoaineai?noth ? ?ioaineai?noth ?iaacoaaiiy ee/eieaie anea?en?a c i?iyaii iiaaiii?e o ii?inyo-nenoi?a. Aea/aii aieea anioe?aoeaiiai ca?aaeaiiy ii?inyo eoeueoo?aie ?iaac?eieo y?oeue A. suum ? aaeoa??e – S. aureus oa E. coli ia ?ioiia?ieia?/iee noai i?aai?cio. ?ic?iaeai? eiiieaeni? caoiaee i?io?eaeoeee ? e?eoaaiiy anioe?aoeaieo iiaaiii?e naeiae. Ia i?aenoaa? i?iaaaeaieo aeine?aeaeaiue cai?iiiiiaai? aeey ai?iaaaeaeaiiy o ae?iaie/eo oiiaao aoaeoeai? eiiieaeni? e?eoaaeueii-i?io?eaeoe/i? noaie c aeei?enoaiiyi aioaaeuei?ioee?a, aioea?ioee?a oa ?ioiiiiaeoethth/iai i?aia?aoo ? iioeiaeuei? no?iee ?o canoinoaaiiy i?e anioe?aoeaieo iiaaiii?yo naeiae. Eeth/ia? neiaa: iiaaiii?y, anea?eic, ee/eiee A. suum, i?e?ii?aai?cie, i?io?eaeoeea, eiiieaenia e?eoaaiiy, aioea?ioeee, aioaaeuei?ioeee. Aaeay E.Ae. Iiaaiiiee naeiae, aucaaiiua anea?eni-iee?iaiuie annioeeaoeeyie e ?ac?aaioea i?ioeeaeoe/aneeo e ea/aaiuo ia?ii?eyoee. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/?iie noaiaie eaiaeeaeaoa aaoa?eia?iuo iaoe ii niaoeeaeueiinoe 03.00.18. – ia?aceoieiaey, aaeueieioieiaey. Einoeooo yenia?eiaioaeueiie e eeeie/aneie aaoa?eia?iie iaaeeoeeiu OAAI, Oa?ueeia, 1999. A aeenna?oaoeee eceaaathony iaoa?eaeu ii eco/aieth annioeeaoeaiuo iiaaiiiee naeiae anea?eni-iee?iaiie i?e?iaeu, a oaeaea ii ?ac?aaioea i?ioeeaeoe/aneeo e ea/aaiuo ia?ii?eyoee i?e yoii caaieaaaiee. Eco/aiea ?ani?ino?aiaiey iiaaiiiee naeiae a oicyenoaao ?aciiai oeia, iaaeaaiiieo/iuo ii anea?eico iieacaei, /oi iie a cia/eoaeueiie ia?a iaoneiaeaiu oaoiieiaeae niaea?aeaiey aeeaioiuo, naciiii aiaea e noaiaiueth eiioaieiaoeee iano iaoiaeaeaiey aeeaioiuo eiaaceiiiuie ia/aeaie e ia caaenaee io oeia niaoeeaeecaoeee oicyenoaa. Onoaiiaeaii, /oi caaieaaaiea a yoeo oicyenoaao iiyaeyaony n 21–30-aeiaaiiai aic?anoa, a ianniaia i?iyaeaiea ?aaeno?e?oaony /a?ac 7–10 nooie iinea iou?ia, o. a. a 65–70 nooie. Iaeaieueoay caaieaaaaiinoue onoaiiaeaia o ii?inyo 2–4-iany/iiai aic?anoa. Auyaeaia acaeiinaycue iaaeaeo yenoaineaiinoueth anea?eiciie eiaacee e o?iaiai caaieaaaaiinoe iiaaiiieyie o ii?inyo 2–4-iany/iiai aic?anoa, a oaeaea iaaeaeo yenoaineaiinoueth e eioaineaiinoueth eiaace?iaaiey ee/eieaie anea?enia n i?iyaeaieai iiaaiiiee o ii?inyo-ninoiia. Onoaiiaeaii, /oi a ianeaaeiaaiiuo naeiiaiae/aneeo oicyenoaao, iaaeaaiiieo/iuo ii anea?eico, iiaaiiiee ?aaeno?e?othony a aeaea annioeeaoeaiiai caaieaaaiey, aaea ia?ae/iay ?ieue a iiyaeaiee iiaaiiiee i?eiaaeeaaeeo ee/eieai A. suum, a oneiaeiytho oa/aiea caaieaaaiey i?eniaaeeiythueany e yoiio i?ioeanno oneiaii-iaoiaaiiua iee?ii?aaieciu (noaoeeieieee, eeoa/iay iaei/ea e ae?.). A noaoeeiia?ii iaaeaaiiieo/iuo ii anea?eico oicyenoaao ec e?aeeo, aieueiuo iiaaiiieae ii?inyo, a aieueoeinoaa neo/aaa auaeaeaiu ia oieueei ee/eiee A. suum, ii e ?acee/iua aeaeu aaeoa?ee: S. aureus, E. coli, S. albus, P. vulgaris e ae?oaea, eioi?ua iinea yenia?eiaioaeueiiai ca?aaeaiey ii?inyo a eaai?aoi?iuo oneiaeyo aucuaaee iiaaiiieth ioaeaeueii, a /anoiinoe, ee/eiee A. suum e S. aureus, e a annioeeaoeee, ii n aieaa oyae?eui oa/aieai. Aaaaeaiea aeeaioiui eoeueoo?u eeoa/iie iaei/ee ia aucuaaei ?acaeoea caaieaaaiey. Annioeeaoeaiia ca?aaeaiea eiaaceiiiuie yeoeaie A. suum e iee?ii?aaieciaie S. aureus e E. coli i?eaiaeeo e ?acaeoeth y?eo?iiaiee, au?aaeaiiiai eaeeioeeoica, oaaee/aiey eiee/anoaa yiceiioeeia, niaiythuaeny iicaeiaa oiaiueoaieai eo, noi?annee O- e A-eeioioeeoia e oa?aeoa?ecoaony aunieei niaea?aeaieai oee?eoee?othueo eiioiiuo eiiieaenia. I?e ea/aiee ii?inyo, aieueiuo iiaaiiieae, onoaiiaeaii, /oi iaeaieaa yooaeoeaiui yaeyeinue eiiieaeniia i?eiaiaiea i?aia?aoia: aioaaeueieioeeia n aioeaeioeeaie (o?cieaaaieciea n “Aaeo?eeii”, oao?aieciea n “Eeaiieneeii”) e aioaaeueieioeea n aioeaeioeeii e eiioiinoeioeyoi?ii (oethaaiiea 5% n “Eeaiieneeii” e iaoeeo?aoeeeii). Eo eniieueciaaiea niinianoaiaaei nieaeaieth caaieaaaaiinoe e onei?aieth aucaei?iaeaiey, i?aaeioa?auaei aeaaeue aeeaioiuo, oaaee/eaaei n?aaeianooi/iua i?e?inou iannu oaea. Onoaiiaeaii, /oi i?eiaiaiea eiiieaeniuo noai ea/aiey i?eaiaeeei e aucaei?iaeaieth aeeaioiuo, /oi iaania/eaaei a naith i/a?aaeue, ii?iaeecaoeeth a eo i?aaiecia eiee/anoaa y?eo?ioeeoia e eaeeioeeoia, niaea?aeaiea iauaai aaeea, oiaiueoaiea o?iaiy OeEE, ainnoaiiaeaiea eiee/anoaaiiuo iieacaoaeae O- e A-eeioioeeoia. ?ac?aaioaiu e i?aaeeiaeaiu a i?iecaiaenoai noaiu i?aeiaaeiaeueiuo aeaaaeueieioecaoeee, i?iaaaeaiea eioi?uo iaiaoiaeeii ia/eiaoue n 14–15-aeiaaiiai aic?anoa, eniieuecoy aioaaeueieioeee oe?ieiai niaeo?a aeaenoaey. I?e/?i, iaeaieaa yooaeoeaiuie i?aia?aoaie ieacaeenue: o?cieaaaiecie, o?oe?aoii n eioa?aaeii 15 nooie e aioaaeueieioee n eiioiinoeioeyoi?ii: oethaaiie 5% 5 nooie iiae?yae n iiaoi?iui aaaaeaieai /a?ac 14 nooie n iaoeeo?aoeeeii ia i?ioyaeaiee 14 nooie. Eniieueciaaiea yoeo i?aia?aoia i?ioeeaeoe?iaaei ca?aaeaiea naeiae anea?enaie ia i?ioyaeaiee 2,5–3 ianyoeaa e i?aaeioa?auaei ?acaeoeth iiaaiiiee. Ia iniiaaiee i?iaaaeaiiuo enneaaeiaaiee i?aaeeiaeaiu aeey aaoa?eia?iie i?aeoeee yooaeoeaiua eiiieaeniua ea/aaii-i?ioeeaeoe/aneea noaiu n eniieueciaaieai aioaaeueieioeeia, aioeaeioeeia e eiioiiiiaeoee?othuaai i?aia?aoa, a oaeaea iioeiaeueiua n?iee eo i?eiaiaiey i?e annioeeaoeaiuo iiaaiiieyo naeiae. Eeth/aaua neiaa: iiaaiiiey, anea?eic, ee/eiee A. suum, iee?ii?aaieciu, i?ioeeaeoeea, eiiieaeniia ea/aiea, aioeaeioeee, aioaaeueieioeee. Bila I. D. Pneumonias in pigs associated with ascariso-bacterial agents and evaluation of prophylaxis and treatment measures. – Manuscript. Thesis for a candidate's degree in veterinary sciences by speciality 03.00.18. – parasitology, helminthology. Institute of experimental and clinical veterinary medicine UAAS, Kharkov, 1999. The materials of studying associative pneumonias of ascariso-bacterial nature are presented in this dissertation work. For the first time the data about spreading of pneumonias at different type farms unfortunate to swine ascariosis were obtained, and the significant role of A. suum larvae in initiating of pneumonias complicated with secondary microbial agents in piglets were proved experimentally. The inter-relation between extensity of Ascaris invasion and level of pneumonias morbidity in piglets 2–4 months of age, and between extensity and intensity of invasion with Ascaris larvae and further development of pneumonias in suckling-pigs. The influence of associative infection of piglets with larvae invasive A. suum such microorganisms as S. aureus and E. coli on the immune state of the organism were studied. New approaches in prophylaxis and treatment of associative pneumonias in pigs are developed. On the base of conducted research the effective combined schemes for prophylaxis and treatment of associative pneumonias in pigs with use of anthelminthics, antibiotics and immunomodulative preparations and optimal terms for it's administration are proposed for adoption in farm conditions Key words: pneumonia, ascariosis, larvae A. suum, bacterial, prophylaxis, combined treatment, antibiotics, anthelminthics.

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