I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

EE?ANUeEA IAAeE*IA AEAAeAI?ss

I?NEssAeEIEIIII? INA?OE ?I. I.E.OOIEEA

?eueei Aiae??e Aaneeueiae/

OAeE 616.33-002.44-06-08:615.838.97;681.3

IAOIAAIAOE*IA IAA?OIOOAAIIss AOAIIIAI E?EOAAIIss AeOIAeAIAEUeII?
AE?ACEE,

ANIOe?EIAAII? C HELICOBACTER PYLORI

14.01.02 — aioo??oi? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a

Iaoeiaee ea??aiee:

Io?oe?ei? iiiiaioe:

I?ia?aeia onoaiiaa:Oaeai?iaenueeiio aea?aeaaiiio oi?aa?neoao?
I?i?noa?noai ina?oe Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? *iiae ?aai Aaneeueiae/, caa?aeoaa/
eaoaae?e i?neyaeeieiiii? i?aeaioiaee e?ea??a Oaeai?iaenueeiai
aea?aeaaiiai oi?aa?neoaoo II Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? Aaaei?ia E?ae?y sse?aia, i?ioani?
eaoaae?e n?iaeii? iaaeeoeeie Ee?anueei? iaaee/ii? aeaaeai??
i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? Iaeauoe Aiaoie?e Iao?iae/, i?ioani?
eaoaae?e aini?oaeueii? oa?ai?? ?2 Iaoe?iiaeueiiai iaaee/iiai
oi?aa?neoaoo ?i. I.I.Aiaiiieueoey IIC Oe?a?ie

?aaii-O?aie?anueea aea?aeaaia iaaee/ia aeaaeai?y IIC Oe?a?ie, eaoaae?a
i?iiaaeaaoeee aioo??oi?o caoai?thaaiue, i. ?aaii-O?aie?anuee

Caoeno a?aeaoaeaoueny “ 24 ” ethoiai 1999 ?. i 11.00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? ?aaee Ae 26.613.01 i?e
Ee?anuee?e iaaee/i?e aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC
Oe?a?ie (254112, i.Ee?a, aoe. Aei?iaiaeeoeueea, 9, aoae. ?3)

C aeena?oaoe??th iiaeia iciaeiieoeny a iaoeia?e a?ae?ioaoe? Ee?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea (254112,
i.Ee?a, aoe. Aei?iaiaeeoeueea,9)

Aaoi?aoa?ao ?ic?neaiee “ 22 ” n?/iy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
I. ?. ?iiaiaiei

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Oai?iae i?aaiia o?aaeaiiy caeiathoue iaeia c
i?iaiaeieo iinoeue ye ii /anoioi ?iaae?aeecaoe??, oae i ii iieacieeo
nia?oiinoi. Ia?aaeae?aceia? noaie (IAN) oa ae?acea aeaaiaaeoeyoeiaei?
eeoee (AAeIE) caeiathoue i?aaaethth/a iinoea a no?oeoo?i caoai?thaaiinoi
i?aaiia OEO. Ca aeaieie aaaaoi/eneaieo aaoi??a a aeiiii?/ii ?icaeiooeo
e?a?iao eeoa iaioe/iith ae?aceith (IA) ia i?ioyc? aeeooy oai??thoue a?ae
10 aei 20 a?aenioe?a anueiai aei?ineiai ianaeaiiy (I.ss.A?eai?ueaa e
niaao., 1993, E.E.Aeaaoy??aa, I.A.Oa?/aiei, 1995, Eiaeiia e niaao.,
1993). A Oe?a?i? /enei aeyaeaieo oai?eo ia iaioe/io ae?aceo ia?aaeuo? 4
i?eueeiie. O 1995 ?ioe? a iao?e e?a?i? c i?eaiaeo oeueiai caoai?thaaiiy
i?iiia?iaaii 29 oeny/ oai?eo ? eeoa o 36 a?aenioe?a c ieo aoea
oneeaaeiaia IA, oiae? ye 64 a?aenioee neeaee ieaiia? iia?aoe??
(A.A.Ia?aaea?ee e niaao., 1997). Caaaeueiia?aeiii, ui, a iniiaiiio,
iaioe/iith ae?aceith oai??thoue ethaee iieiaeiai oa na?aaeiueiai,
iaea?eueo i?aoeacaeaoiiai a?eo, ?, cae/aeii, ?iaae?aeecaoe?y
i?iiia?iaaieo oai?eo caeeoa?oueny iaei??th c iaeaeueo.

IA a?aeiineoueny aei a?oie eeneioicaeaaeieo caoai?thaaiue, ? oiio iiaia
oa aaeaeaaoia ?ioi?iaoe?y i?i noai eeneioiooai?thth/i? ooieoe?? oeoieo
iaaecae/aeii aaaeeeaa aeey ?icoi?iiy iaoiaaiaco, i?iaiico, aeai?o
iaoiaeo e?eoaaiiy oa eiio?ieth ca eiai aoaeoeai?noth (TH.ss.Eay, 1987,
I.ss.A?eai?ueaa e niaao., 1988).

Eiii’thoa?iee aioo??oeoieiaee iii?oi?eia ?I (EAI?I) ? i?ia?aeiei
iaoiaeii ae?aaiinoeee IA, aea? ciiao aea/aoe i?ioeane
eeneioii?iaeoeoe?? (EI) oa eeneioiiaeo?aeicaoei? (EI) o oeoieo a
aeeiaiioei. Ii?yae c oei, aeei?enoaiiy oeueiai iaoiaeo aeicaiey?
ioeiithaaoe aoaeoeaiinoue eieoaaiiy oai?eo ia AAeIE oa IAN
oa?iaeieiai/ieie i?aia?aoaie, oiciioa?aiaaoe/ieie, eo?i?oieiai/ieie
iaoiaeaie, oiui.

Aae?eiaaeoa?ia ?ioaeoe?y – iaeaaaeeea?oee ao?ieia?/iee oaeoi? iaeaea
an?o iaiaaeeeaiaioicieo oeoieiaeo oa aeoiaeaiaeueieo ae?acie. A?eueoa 95
a?aenioe?a oai?eo ia AAeIE ? a?ey 90 a?aenioe?a oai?eo ia
iaiaaeeeaiaioicio aeia?iye?nio ae?aceo oeoieo iathoue oe? aaeoa???.
A?aaeeeaoe?y Helicobacter pylori (I?) i?eaiaeeoue ia eeoa aei
caaeeaeaiiy ae?acie, aea e iiia?aaeaeo? caaino?aiiy oai?iae (E.E.A?oei e
niaao., 1993, I.ss.A?eai?ueaa, 1996, ss.N.Oeeiia?iai e niaao., 1993).

Aea ii?yae c oeei, aaeeeo ?ieue o aeieeiaii? oeueiai caoai?thaaiiy
a?ae?a?a? aaiaoe/ia noeeuei?noue, yea aeia?a a?aeiia a ee?i?oe? ? iiaea
aooe ae?aaiinoiaaia ??cieie iaoiaeaie, a oiio /ene? aeei?enoiaoth/e
ineoieia?/i? oanoe (O.A.Aa?acei e niaao., 1976).

Ia nueiaiaei?oi?e aeaiue cai?iiiiiaaii iaiaei iaoiae?a eiiieaeniiai
e?eoaaiiy AAeIE. ?nio? aace?/ noai i?ioeaae?eiaaeoa?ii? oa?ai??, aea i?
iaeio c ieo ia iiaeia aaaaeaoe ?aeaaeueiith. Iaaooue a ee?i?oe?
aioo??oi?o oai?ia ia ciaeaeaoueny iiae?aiiai caoai?thaaiiy, i?e yeiio
aeei?enoiaoaaeinue ae a?ey 700 ??cieo iina?aaeiee?a oa niinia?a oa?ai??,
aea i?e oiio caeeoaeiny no?eueee a?eeo ieyi a?aeiinii oaeoeee aaaeaiiy,
aeioe?eueiino? aoaiiiai e?eoaaiiy. Ia aeeaey/enue ia oa, ui oi?ioeo
“iaia? I? – iaia? ae?acee” iiaeia ?aooaaoe aeiaaaeaiith, aaaaoi a
e?eoaaii? I?-anioe?eiaaii? IA caeeoa?oueny iayniei. Ia nueiaiaei? ia
?nio? noaie, yea a aeaaaea noia?aenioeiaee ?acoeueoao a?aaeeeaoe??
?ioaeoe?eiiai aaaioa, a c ?ioiai aieo anoaiiaeaii, ui i?eeii
aioenae?aoi?ieo i?aia?ao?a, ye? i?aeo?eiothoue ?I o ii?iaeiei? oeoieo
aeua 3 iae. ?I ia i?ioyc? 18 aiaeei ca aeiao, caaacia/o? caaeeaeaiiy
ae?acee ia i?ioyc? 4 oeaei?a o 100 a?aenioe?a oai?eo (D.W.Burget,
S.G.Chiverton et al., 1990). Oiio iiaeaeueoa aea/aiiy iaoiae?a e?eoaaiiy
caeeoa?oueny aeooaeueiei, ye ? ieoaiiy i?i no/ani? iaoiaee aoaeoeaiiai
eiio?ieth ca i?iaaaeaiiyi ae?i?iaoe?? eaii?eiaaeoa??ico.

Aoaiia e?eoaaiiy oai?eo ia AAeIE, a oiio /ene? c aeei?enoaiiyi
i?ia?aeueieo aiae (IA), aea/aeiny aeineoue ?aoaeueii. Aeiaaaeaii
ni?eyoeeaee eeneioi?aaoethth/ee aieea aoaeaeeneeo a?ae?iea?aiiaoieo
iao???aeo IA (AAIIA) ia aieueoinoue oai?eo c iaoieiai?th
aano?iaeoiaeaiaeueii? ciie (I.O.Eaiae?e, I.I.Aaenae, E.I.Ee?oe/ oa
ni?aaao., 1996). Aea, ii?yae c oeei, cianii ia aea/aia ae?oaa noi?iia ?o
eieoaaeueieo iiaeeeainoae – aioe-I? ae?y. C ?ioiai aieo, aeeeeea?
?ioa?an aea/aiiy aeeiai?ee i?ioean?a eeneioii?iaeoeoe?? oa
eeneioiiaeo?ae?caoe?? a naiaoi?ieo caeeaaeao i?e ??cieo oa?i?iao
e?eoaaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa ?
/anoeiith iaoeiai? i?ia?aie eaoaae?e i?neyaeeieiiii? i?aeaioiaee e?ea??a
iaaee/iiai oaeoeueoaoo Oaeai?iaenueeiai aea?aeaaiiai oi?aa?neoaoo c
oaiaoeee: “Aea/aiiy no?oeoo?ii-ooieoe?iiaeueieo iniia oa iaoai?ci?a
iaoieia?/ieo oa eiiiainaoi?ieo ?aaeoe?e aano?iaeoiaeaiaeueii? nenoaie
na?aae ianaeaiiy Caea?iaooy a oe?eiio oa a ie?aieo iiioeyoe?yo, a oaeiae
i?e ?oai?/i?e oai?ia? na?oey“, iiia? aea?aeaaii? ?a?no?aoe??
0196U003256.

Iaoa ? caaea/? aeine?aeaeaiiy. I?iaanoe eiiieaenia aea/aiiy aoiieiai/ieo
oaeoi?ia oa iaoiaaiaoe/ieo iaoaiiciia ?icaeoeo AAeIE oa IAN, a naia:
?ieue I?-iioaeoei?, ?iceaaeia nenoaie
eeneioii?iaeoeoeiy-eeneioiiaeo?aeicaoeiy o oeoieo a ?icii oace
caoai?thaaiue ca aeiiiiiaith EAI?I, ineoieia?/ieo iniaeeainoae oai?eo,
oa ?ic?iaeoe iioeiaeueii iaoiaee aoaiiiai eieoaaiiy i eiio?ieth ca eiai
aoaeoeaiinoth. Cai?iiiioaaoe aeey oe?ieiai aeei?enoaiiy /?oeo
eiioeaioe?th aoaiiiai e?eoaaiiy oai?eo ia AAeIE.

Aeey ?aaeicaoei? oei?? iaoe aoee iinoaaeaii ianooii? caaea/?:

1. Aea/eoe nooiiiue iioieoaaiiy I? oai?eo ia AAeIE ia ??cieo aoaiao
e?eoaaiiy.

2. Aeineiaeeoe nooiiiue ii?ooaiiy i?ioeania eeneioiooai?aiiy oa
eeneioiiaeo?aeicaoei? o oeoieo oai?eo ia AAeIE ca aeiiiiiaith EAI?I ia
??cieo aoaiao e?eoaaiiy caoai?thaaiiy.

3. Aea/eoe oa?aeoa? ineoieia?/ieo iniaeeainoae oai?eo ia AAeIE.

4. Aeineiaeeoe oa ioeiieoe ?yae aioeaaeieiaaeoa?ieo noai c oi/ee ci?o
aoaeoeaiinoi, i?iyao ieie iiai/ieo aoaeoia oa aa?oinoi. Cai?iiiioaaoe
aei i?aeoe/iiai aeei?enoaiiy aenieiaoaeoeaio ei?ioeino?ieiao noaio
aioe-I? oa?aii?.

5. Aeineiaeeoe eeneioi?aaoethth/o oa aioeaaeieiaaeoa?io aeanoeainoi
AAIIA na?aaeiuei? i?ia?ae?caoe?? oeio “Iieyia Eaaniaa” ia
naiaoi?ii-eo?i?oiiio aoaii eieoaaiiy c a?aooaaiiyi ?icieo oa?iiiia
aaeueiaieiai/ii? oa?aii?.

6.Iaa?oiooaaoe oa ai?iaaaeeoe iiao iaoiaeeeo i?eeiio AAIIA o oai?eo ia
AAeIE, ia?aa??eoe ?? aoaeoeai?noue.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a.

1. Iiaeeaeaii aea/aia ?ieue Helicobacter pylori o aeieeiaii? AAeIE ia
aoaiao e?eoaaiiy.

2. Aea/aiee o aeeiai?oe? noai oeoieiai? eeneioii?iaeoeoe?? oa
eeneioiiaeo?ae?caoe?? oai?eo ia AAeIE i?ae /an noaoe?iia?iiai oa
naiaoi?ii-eo?i?oiiai aoai?a e?eoaaiiy.

3. Anoaiiaeaii ?nioaaiiy ianiaoeeo?/ieo ?iceaae?a ineoieia?/iiai noaio
o oai?eo ia AAeIE.

4. Aeine?aeaeai? oa cai?iiiiiaai? aeey oe?ieiai aeei?enoaiiy iia?
iaoiaeeee i?ioeaae?eiaaeoa?ii? oa?ai??.

5. Aea/aia oa ai?iaiaaia iiaa iaoiaeeea ieoiiai e?eoaaiiy AAIIA
na?aaeiuei? i?ia?ae?caoe?? oai?eo ia AAeIE oa ia IAN. Ioe?iaia
aioeaae?eiaaeoa?ia ?ieue IA “Iieyia Eaaniaa”.

6. Iaa?oioiaaii iaiao?aei?noue aoaiiiai e?eoaaiiy oai?eo ia AAeIE.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

Iaoa??aee aeena?oaoe?? aeei?enoiaothoueny a eaeoe?eiiio eo?n? oa ia
i?aeoe/ieo caiyooyo eaoaae?aie i?neyaeeieiiii? i?aeaioiaee e?ea??a,
aini?oaeueii? oa?ai?? oa i?iiaaeaaoeee aioo??oi?o oai?ia
Oaeai?iaenueeiai aea?aeaaiiai oi?aa?neoaoo, eaoaae?ith aini?oaeueii?
oa?ai?? ? ee?i?/ii? oa?iaeieia?? Aoeiaeinueei? aea?aeaaii? iaaee/ii?
aeaaeai??.

Ca iaoa??aeaie aeena?oaoe?eii? ?iaioe ?ic?iaeai? aea?
?aoe?iiae?caoi?nuee? i?iiiceoe?? (a ni?aaaoi?noa?): “Niin?a e?eoaaiiy
ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee” (iina?ae/aiiy ? 351 a?ae
03.12.96), “Niin?a ae?aaiinoeee aeoiaeaii-aano?aeueiiai ?aoetheno”
(iina?ae/aiiy ? 352 a?ae 03.12.96). Aeai? niiniae ai?iaaaeaeai? a
i?aeoeeo aano?iaioa?ieia?/iiai a?aeae?eaiiy OeIEE i.Oaeai?iaea,
oa?aiaaoe/iiai a?aeae?eaiiy a?aeae?eeiai? e?ea?i? no. Oaeai?iae, IAI
“?aaa?e?oaoe?y” i.Oaeai?iae, naiaoi??th aano?iaioa?ieia?/iiai i?io?eth
“Niiy/ia Caea?iaooy” oa aano?iaioa?ieia?/iiai a?aeae?eaiiy 1-? i?nueei?
e?ea?i? i.*a?i?aoe?. ?acoeueoaoe ai?iaaaeaeaiiy a i?aeoeeo aeiaiaeyoue
?o aenieo aoaeoeai?noue oa i?aeoe/io oe?ii?noue.

Aeaeai? (o ni?aaaoi?noa?) iaoiaee/i? ?aeiiaiaeaoe?? “O?iie/aneee
aano?eo. Nia?aiaiiua i?aaenoaaeaiey i eeanneoeeaoeee, yoeiiaoiaaiaca,
eeeieea e ea/aiee” (Oaeai?iae,1997), ye? ai?iaaaeaeai? a
e?eoaaeueii-i?io?eaeoe/ieo caeeaaeao i.Oaeai?iaea, i?i ui na?ae/aoue
a?aeiia?aei? aeoe.

Iniaenoee aianie caeiaoaa/a. Aianie aaoi?a a io?eiai? ?acoeueoaoe ?
iniiaiei ? iieyaa? o aeai?? ia’?io ? iaoiae?a aeine?aeaeaiiy, a
iinoaiiaoe? iaoe oa oi?ioethaaii? caaaeaiue, a i?iaaaeaii? ee?i?/ieo,
?ino?oiaioaeueieo oa niaoe?aeueieo eaai?aoi?ieo aeine?aeaeaiue, a
aiae?c? oa ocaaaeueiaii? ?acoeueoao?a ?iaioe, iaa?oiooaaii? iaoiae?a
e?eoaaiiy, i?aeaioiaoe? iaoeiaeo iaoa??ae?a aei ae?oeo.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe aeena?oaoe?eii?
?iaioe, ii i??? ?o io?eiaiiy oa aiae?co, aeiiia?aeaeeny oa
iaaiai?thaaeeny ia i?aenoieiaeo iaoeiai-i?aeoe/ieo eiioa?aioe?yo
i?ioani?nueei-aeeeaaeaoeueeiai neeaaeo Oaeai?iaenueeiai aea?aeaaiiai
oi?aa?neoaoo o ethoiio 1996, 1997 oa 1998 ?ie?a, ia Ieaioi? i?aae?iiy
Oe?a?inueeiai iaoeiaiai oiaa?enoaa aa?iioieia?a (*a?i?aoe?, 18-20
aa?aniy 1996 ?ieo), neiiiceoi? “Aeooaeuei? ieoaiiy ?aaa?e?oaoe??
aano?iaioa?ieia?/ieo oai?eo” (i. *a?i?aoe?, 17-18 ea?oiy 1996 ?ieo),
i?aeia?iaei?e eiioa?aioe??, i?enay/ai?e 20- ??//th Oaeai?iaenueei?
a?aeae?eeiai? e?ea?i? “Aeooaeuei? i?iaeaie ianeoaiaoaaiiy i?aoethth/eo
ia cae?cie/iiio o?ainii?o?” (i.Oaeai?iae, 12-14 /a?aiy 1996 ?ieo),
i?aenaiaoi?iiio caiyoo? e?ea??a ia’?aeiaiiy “Caea?iaoeo?i?o” o
eenoiiaae? 1997 ?ieo, Ainueiiio i?aeia?iaeiiio eiia?an? ?ioaeoe?eieo
oai?ia (i.Ainoii, ooao Iana/onaon, NOA, 15-18 o?aaiy 1998 ?ieo) oa XIV
c’?cae? oa?aiaao?a Oe?a?ie (i. Ee?a, 22-25 aa?aniy, 1998 ?ieo).

Aeena?oaoe?y ai?iaiaaia 17 aa?aniy 1998 ?ieo ia ni?eueiiio can?aeaii?
eaoaae? i?neyaeeieiiii? i?aeaioiaee e?ea??a, aini?oaeueii? oa?ai?? oa
i?iiaaeaaoeee aioo??oi?o oai?ia iaaee/iiai oaeoeueoaoo Oaeaeo i?e
i?enooiino? ni?a?ia?oiee?a oa?aiaaoe/iiai a?aeae?eaiiy Oaeai?iaenueei?
a?aeae?eeiai? e?ea?i?.

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 12 iaoeiaeo
i?aoeue, c ieo: 5 – o iaoeiaeo aeo?iaeao, 1 – o iaoeiaiio ca??ieeo, 6 –
o iaoa??aeao neiiiceoi?a oa eiia?an?a, a oiio /ene? aeaio, ye?
i?iaiaeeeeny ca ei?aeiiii.

No?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 132 noi??ieao
iaoeiiieno, aeeth/a? 25 oaaeeoeue oa 18 ?enoie?a. ?iaioa iiaoaeiaaia ca
caaaeueiii?eeiyoei ieaiii ? neeaaea?oueny ?c anooio, 6 ?icae?e?a, a oiio
/ene? ?acoeueoao?a aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo aeei?enoaieo aeaea?ae, yeeo
ia?aoiao?oueny o ?iaio? 285, c ieo 121 a?o/eciyieo (a oiio /ene? ?
?in?enueeiiiaieo) oa 164 ca?oa?aeieo aaoi??a, a oaeiae aeiaeaoe?a.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiue. Aeey ae?ioaiiy iinoaaeaieo caaea/
iaie aoei ianoaaeaii 159 oaiaoe/ieo oai?eo. C ieo — 125 oai?eo ia AAeIE,
a oiio /enei 95 o oaci caaino?aiiy, 30 o oaci ?aiini?; 34 oai?eo ia OA
A, a oiio /enei 18 a oaci caaino?aiiy, 16 a oaci ?aiini?. Aeineiaeaeaiiy
95 oai?eo ia AAeIE oa 18 oai?eo OA A o oaci caaino?aiiy i?iaiaeeeiny o
oa?aiaaoe/iiio oa iieieeiii/iiio aiaeaeieaiiyo aiaeaeieeiai? eeiii/ii?
eiea?ii no.Oaeai?iae oa aano?iaioa?ieiai/iiio aiaeaeieaiii OeIEE
i.Oaeai?iaea, 30 oai?eo ia AAeIE, 16 oai?eo OA A o oaci ?aiini? — o
aaciaiio naiaoi?i? aano?iaioa?ieiai/iiai i?ioieth “Niiy/ia Caea?iaooy”.
Ianoaaeaiiy aeeiioaaeeny ca ia?iiae 1996-1998 ??.

A yeinoi eiio?ieueii? a?oie aeei?enoaii 44 i?aeoe/ii caei?ia? iniae, a
oaeiae 33 oai?eo ia a?iioiaeueio anoio oa o?iii/iee a?iioio o oaci
?aiini?, yei i?ioiaeeee eieoaaiiy o IAI ”?aaaieioaoeiy” i.Oaeai?iae.

Aeai?eoi ae?aaiinoeee IA oa OA A ii/eiaany c ae?aaiico “Aeeniain?y”,
yeee i?ney aeei?enoaiiy ee?i?ei-?ino?oiaioaeueieo iaoiae?a
o?ainoi?ioaaany o a?aeiia?aeio iicieia?/io iaeeieoeth. Ia iiiaio
caaa?oaiiy iaienaiiy ?iaioe ie ei?enooaaeeny eeaneo?eaoe??th IA,
iaeneiaeueii aaeaioiaaiith aei IEO O ia?aaeyaeo (E.E. Aeaaoy??aa,
I.A.Oa?/aiei, 1995; A.A.Ia?aaea??e, 1997). Oaeei /eiii, a iao?e ?iaio?
iaioe/ia ae?acea — oea neiii?i ae?aceiai? oai?iae.

Uiaei OA, iaie aeei?enoiaoaaeany oae caaia N?aeiaenueea eeaneo?eaoe?y
1990 ?ieo, a c 1996 ?ieo ie a?aoiaoaaee oaeiae ?aeiiaiaeaoe?? ?iai/i?
O’thnoiinueei? a?oie (E.E.A?oei, 1997).

Aoaii?noue aeine?aeaeaiiy caaacia/oaaeany ?o i?iaaaeaiiyi a
aiaoeaoi?ii-noaoe?iia?ieo oa naiaoi?ii-eo?i?oieo oiiaao.

Aecia/aiiy I?-iioaeoei? i?iaiaeeeiny ca aeiiiiiaith a?noieia?/iiai
iaoiaeo, o?aaciiai oanoo c aeei?enoaiiyi na?aaeiaeua Caena oa iaoiaeo
oaapaeioaciiai iiyiioapiaioiiai aiaeico (iaai? ImmunoComb II,
ae?iaieoeoaa ?c?a?eth).

Aeine?aeaeaiiy EI oa EI ooieoei? oeoieo aeeiioaaeeny aia?aoaie
“Oiiaa?naeueiee iiiiii? AA — 74” c iaai?ii aeaieaiaeueieo ciiaeia
?.TH.E?ia?a oa AA 1Ae-01 c aeaieaiaeueieie ciiaeaie IA-?I-2. Aea/aiiy
i?/ii? nae?aoe?? oeoieo i?iaiaeeee ca aeiiiiiaith EAI?I
(A.I.*a?iia?iaee, 1989). Aeey oeueiai iaie aeei?enoaiee eiiieaen, yeee
aeeth/aa iaeiie/oaa/ ?I-iao?e/ii? ?ioi?iaoe??, eiii’thoa?, a?aeiia?aeio
i?ia?aio c aeiiii?aeieie aeaiaioaie nenoaie, ?I-i?e?iciiaeaie oa ?ioeie
i?eno?iyie. Aaoiiaoe/ia ?a?no?aoe?y ?I ia i?ioyc? ii/? i?iaiaeeeany c
?ioa?aaeii a 16 naeoiae. Aeey ooieoeiiioaaiiy eiiieaeno ie
aeei?enoiaoaaee ia?niiaeueio AII oeio ?AI ?N AO/OO — 486 c ia?eoa?i?th
(aeenieae, eeaaiaoo?a, i?eioa?).

Caien iieacieeia i?/ii? nae?aoe?? oeoieo i?iaiaeeee c 23.00. aei
06.00., a a naiaoi?ieo oiiaao — aei 07.00, oiio ui ia oeueiio aoai?
aea/aeany oaeiae aioaoeeaeia ae?y iaeii?aciaiai i?eeiio 200 ie IA
“Iieyia Eaaniaa”.

Aeineiaeaeaiiy ineoieia?/ieo iniaeeainoae oai?eo i?iaiaeeee ca
aeiiiiiaith Iiiianionueeiai aieaoiiai oanoo (II?? — Minnesota
Multiphasic Personality Inventory). Io?eiaiee a ?acoeueoaoi
aeineiaeaeaiue oeeo?iaee iaoa?iae ia?iaeaiee c aeei?enoaiiyi
noaiaea?oieo noaoenoe/ieo iaoiaeia ic ciaoiaeaeaiiyi na?aaeiuei?
aaee/eie (I), na?aaeiuei? iioeaee na?aaeiuei? aaee/eie (m), iieaciee?a
?iia??iino? Nouethaeaioa (t) oa ai?iaiaeiinoi (?).

Iniiai? ?acoeueoaoe aeine?aeaeaiiy. ??aaiue ?io?eoaaiiy I? i?aeoe/ii
caei?iaeo in?a neeaa 37,5%, o oai?eo ia aeoiaeaiaeueio ae?aceo
I?-?ioaeoe?th ciaoiaeeee a 92,3%. Na?aaeiie iieaciee eiioeaio?aoe??
aio-I? Ig G o eiio?ieueii? a?oie noaiiaea 53,3 iae/ie, a o oai?eo ia
AAeIE – 65,1 iae/ie. Eiioeaio?aoe?y aioeo?e aei I? o oai?eo ia AAeIE ia
aoea a??ia?aeii aeuith a ii??aiyii? c caei?iaeie iniaaie ? ia iiaea
aeei?enoiaoaaoeny ye aeeoa?aioe?eiee ae?aaiinoe/iee oano.

I?e aea/aii? aoaeoeaiino? ?yaeo iaaeeeaiaioicieo noai c oi/ee ci?o
aeiiiiaoei? I?, /anoioe ?oaoethaaiiy ae?acee /a?ac o?e oeaei?,
ae?aaeaiino? iia?/ieo aoaeo?a oa aa?oino?, ca iaoeie aeaieie,
iaeaoaeoeai?oeie noaiaie a ieai? a?aaeeeaoei? I?-iioaeoei? aoee
eiiaiiaoei? aiieneoeeeiio (500 ia 4 ?ace ia aeaiue), caioaeo (150 ia 2
?ace ia aeaiue) oa aea-iieo (120 ia 4 ?ace ia aeaiue), ye? oai?? ia
AAeIE i?eeiaee ia i?ioyc? 14 aeiia; aea-iieo (120 ia 4 ?ace ia aeaiue),
oao?aoeeeeiio (500 ia 4 ?ace ia aeaiue) oa iao?iiiaeacieo (250 ia 3
?ace) — 14 aeiia; aea-iieo (120 ia 4 ?ace ia aeaiue), aiieneoeeeiio (500
ia 4 ?ace ia aeaiue) oa iao?iiiaeacieo (250 ia 3 ?ace ia aeaiue) — 14
aeiia; iiai?acieo (40 ia 1 ?ac ia aeaiue), yeee i?eeiaee i?ioyaii
oeaeiy, aceo?iiioeeio (c 5 aeiy ii 500 ia 1 ?ac ia aeaiue) oa
iao?iiiaeacieo (c 5 aeiy 500 ia 3 ?ace ia aeaiue), ye? i?eeiaee ia
i?ioyci 3 aeiia.

Ne?ae ie?aii i?aee?aneeoe, ui ye eeane/ia, oae ? cai?iiiiiaaia iaie
noaia c iiai?acieii, aceo?ii?oeeiii oa iao?ii?aeacieii, e??i oeueiai, ?
e aeiiiii/ii aeaiaeieie. O?ioe aieueoee (87,5% i?ioe 83,3%)
a?aaeeeaoeieiee aoaeo iaei cai?iiiiiaaia ei?ioeino?ieiaa i?ecia/aiiy
iiai?acieo, aceo?ii?oeeio oa iao?ii?aeacieo, ? oey eiia?iaoe?oey ?
c?o/iith o aeei?enoaii? oai?eie.

A ?acoeueoao? i?iaaaeaiiai noaoe?iia?iiai e?eoaaiiy o a?eueoino? oai?eo
ia AAeIE cieeea iniiaia neiioiiaoeea. Aieueiaee neiae?ii caeeoaany /a?ac
o?e oeaei? i?ney ii/aoeo oa?ai?? o 13% in?a, c ieo o 4, ui io?eioaaee
ieaoeaai, ia??iaee/i? a?ae?eaeea eeneei — o 35%, ia/?y o 11% oa cae?aie
o 30% oai?eo ia aeoiaeaiaeueio ae?aceo (i?e iinooieaii? a?aeiia?aeii o
92,6%, 43%, 48,4% oa 53,7% oai?eo).

I?iyae iia?/ieo aoaeo?a aeine?aeaeoaaieo iaaeeeaiaioicieo noai aoee
i?i?iaeueieie ? aeyaeai? o 9 ?c 77 oai?eo (11,7%).

I?e aea/aii? i?ioean?a EI oa EI o eiio?ieuei?e a?oi? in?a na?aaei?e
iieaciee ?I oiea oeoieo noaiiaea 1,6424+0,062 iae. ?I, a a aio?aeuei?e
/anoei? – 4,6092+0,357 iae. ??aaiue EI ciaoiaeeany a iaaeao
ii?iaoeeaeiino?, a EI, oiaoi ??cieoey i?ae iieacieeii ?I o o?e? oa
aio?aeuei?e /anoei? oeoieo, noaiiaeea 2,9668.

Na?aaei?e iieaciee ?I o o?e? oeoieo oai?eo ia AAeIE o oac? caaino?aiiy
noaiiaea 1,2642+0,060, o oai?eo ia OA A o oac? caaino?aiiy –
1,3744+0,077 iae. ?I. Oiaoi, a iaeaeaio a?oiao iieacieee ?I o?ea oeoieo
iiaeia ioa?aeoa?ecoaaoe, ye iii??ii a?ia?aoeeaei?. sse o oai?eo ia
AAeIE, oae ? OA A io?eiai? iieacieee ?I o?ea oeoieo a??ia?aeii
a?ae??ciyeeny a?ae aiaeia?/ieo eiio?ieueii? a?oie (? < 0,001 oa < 0,02 a?aeiia?aeii). Iieacieee ?I a aio?aeueiiio a?aeae?e? oeoieo oai?eo ia AAeIE o oac? caaino?aiiy noaiiaeee 2,0518+0,161, oai?eo ia OA A – 2,2161+0,268 iae. ?I. I?e ii??aiyii? io?eiaieo ?acoeueoao?a oeeo a?oi oai?eo c aiaeia?/ieie iieacieeaie i?aeoe/ii caei?iaeo in?a anoaiiaeaii, ui ?nioaaea a??ia?aeia ??cieoey ye o oai?eo ia AAeIE, oae ? OA A (? < 0,001). Aeeeeea? ?ioa?an, ui iieacieee ?I a aio?aeuei?e /anoei? oeoieo ye o oai?eo ia AAeIE, oae ? OA A aoee ??cei cieaeai? (EI o oai?eo ia AAeIE noaiiaeea 0,7876, a o oai?eo ia OA A – 0,8417 iae. ?I). Ia a?aei?io a?ae oeueiai, i?ae iieacieeaie ?I oai?eo ia AAeIE oa OA A o oac? caaino?aiiy ia ?nioaaei a??ia?aeii? ??cieoe? ye o o?e?, oae ? a aio?aeueiiio a?aeae?e? oeoieo (? > 0,2 oa > 0,6 a?aeiia?aeii).

Iieacieee ?I o o?e? oeoieo oai?eo ia AAeIE o oac? ?ai?n?? noaiiaeee
1,3792+0,089 iae. ?I. C ?ioiai aieo, o oai?eo ia OA A o oac? ?ai?n?? oe?
iieacieee aoee 1,3571+0,145 iae. ?I. A aio?aeueiiio a?aeae?e? oeoieo
aiie noaiiaeee a?aeiia?aeii 3,9950+0,235 oa 3,2928+0,318 iae. ?I.

I?e ii??aiyii? aeaieo iieaciee?a c aiaeia?/ieie eiio?ieueii? a?oie
anoaiiaeaii, ui o iaio aeineiaeaeoaaieo eiioeiaaio?a oai?eo inioaaea
a??ia?aeia ??cieoey iieaciee?a ?I o?ea oeoieo oa aio?aeueiiai a?aeae?eo
ye a oaci caaino?aiiy, oae ? ?ai?n??. C ?ioiai aieo, ia ciaeaeaii
a??ia?aeieo ciii i?ae iieacieeaie EI oeeo a?oi oai?eo o ??cieo oacao
caoai?thaaiue iaa?oue /a?ac 3-7 i?nyoe?a i?ney caaino?aiiy (? > 0,2 oa >
0,3 a?aeiia?aeii). Oe?eaai, ui a??ia?aei? ci?ie ciaeaeai? aeey
iieaciee?a ?I a aio?aeueiiio a?aeae?e? oeoieo (? < 0,001 oa ? < 0,02 a?aeiia?aeii). I?e aea/aii? noaio i?/ii? EI oeoieo oai?eo ia AAeIE o oac? caaino?aiiy ie io?eiaee ?acoeueoaoe, ye? a?aeia?aaeaii ia ?en.1: a?ae 23.00 aei 00.40 niinoa??aaeany ae?aaeaia a?ia?aoeeaei?noue (?I 0,9-1,2), a?ae 00.50 aei 01.40 oa o 06.00 – iii??ia a?ia?aoeeaei?noue (?I 1,3-1,5), ?aooa /ano – ii?iaoeeaei?noue (?I 1,6-2,2) aai iaa?oue iii??ia a?iiaoeeaei?noue (?I 2,3-3,5). Aeey oe??? a?oie oai?eo aoei oa?aeoa?iei aeayea i?aeaeuaiiy ??aiy ?I, yea niinoa??aaeiny i?eaeecii c 2 aiaeeie ii/? ? ? iane?aeeii oaiiiaio iieoaeiaiiy oeoieo o /anoeie oai?eo. Na?aaei?e ??aaiue iieaciee?a i?/iiai ?I noaiiaea 1,7076 iae. ?I. 9 ?en.1 O?iiieia?/i? iieacieee i?/iiai ??aiy ?I o?ea oeoieo oai?eo ia ae?aceo aeaaiaaeoeyoeiaei? eeoee: a?ao?e ? – o oac? caaino?aiiy ; a?ao?e ?? – o oac? caaino?aiiy i?ney i?eeiio i 21.00 150 ia ?ai?o?ae?io; a?ao?e ??? – o oac? ?ai?n??; a?ao?e IV – o oac? ?ai?n?? ia 8-12 aeaiue naiaoi?iiai e?eoaaiiy c aioo??oi?i i?eeiiii i?ia?aeueii? aiaee “Iieyia Eaaniaa”; a?ao?e V – o oac? ?ai?n?? ia 20-24 aeaiue naiaoi?iiai e?eoaaiiy c aioo??oi?i i?eeiiii i?ia?aeueii? aiaee “Iieyia Eaaniaa” oa a in?a eiio?ieueii? a?oie (a?ao?e VI). O eiio?ieueii? a?oie in?a na?aaei? iieacieee ?I o?ea oeoieo ca i?/ noaiiaeee 1,8167 iae. ?I. I?iaiae?coaaaoe ?acoeueoaoe iieaciee?a ?I ca ie?aieie aiaeeiieie ?ioa?aaeaie, ie io?eiaee: ii?iaoeeaei?noue niinoa??aaeany i?aeoe/ii ia i?ioyc? on??? ii/?, ca aeeeth/aiiyi iii??ii? a?iiaoeeaeiino? i 03.40 oa 04.20 – 04.40, ?, iaaiaee, a?ia?aoeeaei?noue niinoa??aaeany i 02.40 oa i 05.30 (aeea. ?en. 1). Ii??aiyaoe o?iiieia?/i? i?/i? iieacieee ?I o?ea oeoieo o oai?eo ia AAeIE o oac? caaino?aiiy oa eiio?ieueii? a?oie anoaiiaeaii, ui a??ia?aei? ci?ie aoee oa?aeoa?ieie ia i?ii?aeeo /ano a?ae 23.00 aei 00.40 (? < 0,05).I?ia?aoe aiae?c iieaciee?a eiii’thoa?ii? i?/ii? ?I a?aie o oai?eo ia AAeIE o oac? ?ai?n??, ie io?eiaee ianooii? aeai?: na?aaei?e ??aaiue iieaciee?a ?I noaiiaea 1,6369. Ae?aaeaia a?ia?aoeeaei?noue niinoa??aaeany i 23.00, 23.20-23.30, iii??ia a?ia?aoeeaei?noue – i 23.10, 23.40-01.30, 01.50, 02.10-02.30, 05.10, 05.50-06.00, ii?iaoeeaei?noue – i 01.40, 02.00, 02.40-05.00, 05.20-05.40, iii??ia a?iiaoeeaei?noue – i 03.50. I?ney ii??aiyiiy na?aaeiueia?oiiaeo iieaciee?a ?I-a?ai o?ea oeoieo oai?eo ia AAeIE o oac? caaino?aiiy oa ?ai?n?? i?ae niaith ie ia io?eiaee a??ia?aeii? ??cieoe? ia i?ioyc? an??? ii/? (? > 0,05). C ?ioiai aieo,
aiia ?nioaaea o na?aaeiueia?oiiaeo cia/aiiyo i?/ieo iieaciee?a ?I o?ea
oeoieo oai?eo ia AAeIE ye o oac? ?ai?n??, oae o oac? caaino?aiiy, i?e
ii??aiyii? c eiio?ieueiith a?oiith a ia?o?e iieiaei? ii/?. A oac?
?ai?n?? oey ??cieoey niinoa??aaeany ia i?ii?aeeo /ano a?ae 23.00 aei
00.20 (? < 0,05). I?e aiae?c? iieaciee?a i?/iiai ??aiy ?I aio?aeueiiai a?aeae?eo aeine?aeaeoaaieo a?oi io?eiaii aeai?, ca?aeii yeeo na?aaei?e iieaciee ?I aio?aeueiiai a?aeae?eo oeoieo o oai?eo ia AAeIE o oac? caaino?aiiy aii/? noaiiaea 2,4182+0,117 iae. ?I, o oac? ?ai?n?? – 3,562+0,2134 iae. ?I, o in?a eiio?ieueii? a?oie – 4,4333+0,24 iae. ?I. Io?eiaii a??ia?aeio a?aei?ii?noue iiae cia/aiiyie ?I aio?aeueiiai a?aeae?eo a?oi oai?eo ia AAeIE a iaio oacao oa eiio?ieueiith a?oiith (? < 0,001 oa < 0,05). Aiaeia?/io a?aei?ii?noue anoaiiaeaii i?ae i?/ieie iieacieeaie ?I aio?aeueiiai a?aeae?eo oeoieo oai?eo ia AAeIE a iaio oacao caoai?thaaiiy (? < 0,01). Na?aaei? cia/aiiy iieaciee?a ?I o?ea oeoieo oai?eo ia AAeIE o oaci caaino?aiiy, ye? i?eeiaee ?ai?o?ae?i a aeic? 150 ia ia?i?aeueii i 21.00, noaiiaeei 5,1707 iae. ?I, a noai EI ia i?ioyc? ii/? a?ae 23.00 aei 06.00 iiaeia ioa?aeoa?ecoaaoe, ye ae?aaeaia a?iiaoeeaei?noue. Ne?ae a?aei?oeoe, ui i?e noaoenoe/i?e ia?iaoe? a??ia?aei? ci?ie inioaaee ia i?ioyc? on??? ii/?. Iieacieee ?I a aio?aeuei?e /anoei? oeoieo i?e i?eeii? ?ai?o?ae?io noaiiaeee 6,4857+0,410 iae. ?I (? < 0,001). Ia iao iiaeyae, ia nueiaiaei? i?eioeeiiaei ieoaiiyi caeeoa?oueny aea/aiiy iniaeeainoae oai?iai, ye noano?aoo i?iyao oeueoea?iaaiieo oaeoi??a. Aeey aeinyaiaiiy oe??? iaoe ie ? aeei?enoaee caaaeueiia?aeiiee oano II??, yeee aeicaiey? noaeeoe i?i ineoieia?/i? iniaeeaino? in?a. Io?eiai? ?acoeueoaoe iieacaee, ui a??ia?aeia ??cieoey ?nioaaea i?ae i?io?eyie a?oi oai?eo ia AAeIE oa eiio?ieueiith a?oiith o oeaeao F, K, 1, 2, 4, 6, 7, 8, 0. Oeaee 1, 2 oa 7 /?oei a?aeia?aaeathoue oa?aeoa? iaa?ioe/ieo neiae?ii?a ? aeacothoue ia oa, ui o aeaieo oai?eo ia IA niinoa??aaeany i?aeaeuaia aioo??oiy iai?oaa, o?eaiaa, no?aoe, iaiioeaiaaia aiyceea?noue, ianei?noe/ia ioe?iea ia?niaeoeae, i?aeaeuaia oo?aioa ca noai naiai o?ce/iiai caei?ia’y, neaioeoeeci, iaaeia??a aei iaaee/ii? aeiiiiiae, iaaiaaiai?noue o nia? oa a eiiiaoaioiino? ioi/oth/eo, a ii??aiyii? c? caei?iaeie ethaeueie. Ia naiaoi?ii-eo?i?oiiio aoai? oa?ai?? o oai?eo ia AAeIE oa OA A ? A+A o aeeiai?oe? aei??thaaeeny iieacieee aacaeueiiai ??aiy ?I a?aioe? c aea/aiiyi iaeii?aciaiai i?eeiio 200 ie IA oa i?/iee EAI?I c 23.00 aei 7.00 o oae? aei? e?eoaaiiy: 1-4, 8-12 oa 20-24. I?e oeueiio oai?? i?eeiaee IA “Iieyia Eaaniaa” ca iiaith, cai?iiiiiaaiith iaie iaoiaeeeith: ii 150 ie oaiei?, a?ey 40°N, aeaaaciaaii? IA aeieaaeiny ae??aieie eiaoeaie /a?ac 1-1,5 ? 3 aiae i?ney i?eeiio ?ae?. I?e aeienoe? c naiaoi??y iie?auaiiy caaaeueiiai ee?i?/iiai noaio niinoa??aaeiny o 90% oai?eo ia IA oa 93,8% oai?eo ia OA A, ??cei ciaioeeany e?euee?noue nea?a ia aieueiaee neiae?ii, ia/?th, a?ae?eaeeo eeneei oa cae?aie. Io?eiaii a??ia?aeia i?aeaeuaiiy iieaciee?a aacaeueiiai ??aiy ?I o?ea oeoieo oai?eo ia AAeIE oa OA A (? < 0,001). Ia 8-12 aeaiue e?eoaaiiy a naiaoi??? iieacieee ?I i?aeaeueeeny a?aeiia?aeii ia 1,7208 (c 1,3792+0,089 iae. ?I aei 3,1000+0,249 iae.) ? 1,9352 iae. ?I (c 1,3571+0,145 aei 3,2923+0,394 iae. ?I), ca aanue ia??iae a?aeiia?aeii ia 2,1779 (c 1,3792+0,089 aei 3,5571+0,278 iae. ?I) ? 1,4857 iae.?I (c 1,3571+0,145 aei 2,8428+0,398 iae. ?I). Uiaei aeeiai?ee noaio ?I aio?aeueiiai a?aeae?eo oeoieo, oi ia 8-12 aeaiue aeine?aeaeaiiy a?aeaoeeny a??ia?aei? ci?ie a noi?iio i?aeaeuaiiy iieaciee?a ?I, ye o oai?eo IA, OA A, oae ? OA A+A. Iieacieee EI iie?aueeeny o oai?eo ia AAeIE, OA A oa OA A+A a?aeiia?aeii ia 2,1402 (c 3,995+0,235 aei 6,1352+0,213 iae. ?I (? < 0,001)), 2,5841 (c 3,2928+0,318 aei 5,8769+0,319 iae. ?I (? < 0,001)) oa 0,8345 iae. ?I (c 5,9382+0,211 aei 6,7727+0,181 iae. ?I (? < 0,002)). Ca aanue ia??iae e?eoaaiiy iieacieee EI a??ia?aeii i?aeaeueeeny o ia?oeo aeaio a?oi oai?eo ia 1,6682 (c 3,995+0,235 aei 5,6632+0,245 iae. ?I (? < 0,001)) oa 1,7610 iae.?I (c 3,2928+0,318 aei 5,0538+0,379 (? < 0,002)) a?aeiia?aeii. I?e aea/aii? aioaoeeaeii? ae?? i?e iaeii?aciaiio i?eeii? 200 ie IA caa?oa? ia naaa oaaao oaeo a??ia?aeieo ci?i, ye? a?aeaoaaeeny a ?acoeueoao? oeueiai aieeao ye o oai?eo ia AAeIE, oae ? OA A i?ioyaii an?o oa?i?i?a e?eoaaiiy (? < 0,01). I?e aiae?c? aioaoeeaeii? ae?? IA a ??ci? oa?i?ie e?eoaaiiy ne?ae i?aee?aneeoe, ui a?aeaoeiny a??ia?aeia i?aeaeuaiiy iaeneiaeueiiai ??aiy iieaciee?a ?I o oai?eo ia AAeIE oa OA A, ui iiina?aaeeiaaii na?ae/eoue i?i ciaioaiiy e?eueeino? oeoieiaiai nieo oa eiai eeneioiino? (? < 0,05). Ca ia?oo iieiaeio e?eoaaiiy iieacieee iaeneiaeueiiai ??aiy ?I ci?ieeeny o oai?eo ia AAeIE oa OA A ia 0,912 iae. (c 4,7880+0,198 aei 5,7+0,188 iae. ?I) oa 1,6539 iae. (c 4,3642+0,257 aei 6,0181+0,201), a ca iiaiee ia??iae ia 0,9598 (c 4,7880+0,198 aei 5,7478+0,178 iae. ?I) oa 1,3281 iae. ?I (c 4,3642+0,257 aei 5,6923+0,283 iae. ?I) a?aeiia?aeii. Uiaei oa?aeoa?o i?/ii? nae?aoe??, oi, ye aeaeii c ?en. 1, o oai?eo ia AAeIE o oac? ?ai?n?? a ia?oo iieiaeio ii/? (a?ae 23.00 aei 02.30) oa ?aieii o 05.10 oa 05.50-06.00 niinoa??aaeany a?ia?aoeeaei?noue, ia?aaaaeii iii??ia, a ?ioee /an – ii?iaoeeaei?noue. A??ia?aeia i?aeaeuaiiy iieaciee?a (? < 0,05) i?/iiai ??aiy ?I o?ea oeoieo (cieaeaiiy eeneioiino?) o oe??? a?oie oai?eo a?aeaoeiny ia i?ii?aeeao /ano a?ae 23.00 aei 00.30, a?ae 02.10 aei 03.10 oa a?ae 05.50 aei 06.00 i?ney ia?oiai ia??iaeo e?eoaaiiy oa i?ioyaii on??? ii/? i?ney iiaiiai ia??iaeo aaeueiaieia?/ii? oa?ai??. Noai i?/ii? oeoieiai? nae?aoe?? ia 8-12 aeaiue iiaeia ioa?aeoa?ecoaaoe, ye ia?aaaaeii iii??io a?iiaoeeaei?noue, ia 20-24 aeaiue - ae?aaeaio a?iiaoeeaei?noue. Iniaeeai aaaeeeaei ? oie oaeo, ui aeinoia??ia i?aeaeuaiiy iieaciee?a ?I a?aeaoeiny ia i?ii?aeeao /ano c a?ia?aoeeaeieie iieacieeaie ia ii/aoeo e?eoaaiiy. Na?aaei? iieacieee i?/iiai ??aiy ?I o?ea oeoieo neeaee: ia ii/aoeo e?eoaaiiy 1,6369 iae. ?I, a na?aaeei? – 3,0794 iae. ?I, a e?ioe? – 4,2910 iae. ?I. O oai?eo ia OA A o oac? ?ai?n?? a ia?oo iieiaeio ii/? (a?ae 23.00 aei 01.00) ia 1-4 aeaiue e?eoaaiiy niinoa??aaeany iii??ia a?ia?aoeeaei?noue, a ianooiiee ia??iae – ii?iaoeeaei?noue oa iaa?oue iii??ia a?iiaoeeaei?noue. A??ia?aeia i?aeaeuaiiy iieaciee?a i?/iiai ??aiy ?I o?ea oeoieo (cieaeaiiy eeneioiino?) o a?oi? oai?eo ia OA A a?aeaoeiny ia i?ii?aeeao /ano a?ae 23.00 aei 00.30 i?ney ia?oiai ia??iaeo e?eoaaiiy oa a?ae 23.00 aei 01.40 i?ney iiaiiai ia??iaeo aaeueiaieia?/ii? oa?ai?? (? < 0,05). Noai i?/ii? oeoieiai? nae?aoe?? ia 8-12 aeaiue iiaeia ioa?aeoa?ecoaaoe, ye ia?aaaaeii iii??ia a?iiaoeeaei?noue a ia?o?e iieiaei? ii/? oa ae?aaeaia a?iiaoeeaei?noue o ae?oa?e, ia 20-24 aeaiue – ia?aaaaeii ae?aaeaia a?iiaoeeaei?noue. Aaaeeeaei ? oa, ui a??ia?aeia i?aeaeuaiiy iieaciee?a ?I oaeiae a?aeaoeiny ia i?ii?aeeao /ano c a?ia?aoeeaeieie iieacieeaie ia ii/aoeo e?eoaaiiy. Na?aaei? iieacieee i?/iiai ??aiy ?I o?ea oeoieo oai?eo ia OA A neeaee: ia ii/aoeo e?eoaaiiy 2,4739 iae. ?I, a na?aaeei? – 3,7223 iae. ?I, a e?ioe? – 4,4672 iae. ?I. I?e ioe?ioe? i?/ieo iieaciee?a aio?aeueiiai a?aeae?eo oeoieo aeine?aeaeoaaieo a?oi oai?eo io?eiaii ?acoeueoaoe, ca?aeii yeeo, na?aaei? iieacieee ?I aio?aeueiiai a?aeae?eo aii/? neeaee ia ii/aoeo e?eoaaiiy, a na?aaeei? oa a e?ioe? o oai?eo ia AAeIE o oac? ?ai?n?? a?aeiia?aeii: 3,5625+0,259, 5,8500+0,308 oa 5,9128+0,359 iae. ?I; o oai?eo ia OA A o oac? ?ai?n?? a?aeiia?aeii: 3,3129+0,287, 5,6502+0,391 oa 5,8144+0,371 iae. ?I; o oai?eo ia OA A+A o oac? ?ai?n?? a?aeiia?aeii: 5,7760+0,161, 6,5631+0,154 oa 6,2483+0,316 iae. ?I. A??ia?aei? ci?ie oa?aeoa?i? aeey an?o o?ueio a?oi oai?eo i?ioyaii ia?oi? iieiaeie e?eoaaiiy oa aeey ia?oeo aeaio a?oi oai?eo i?ioyaii onueiai eo?no aaeueiaieia?/ii? oa?ai?? (? < 0,01). C’yniaaii, yeui i?e caaaeueiii?eeiyo?e iaoiaeeoe? i?eeiio IA ??cieoey a i?aeaeuaii? iieaciee?a aacaeueiiai ??aiy ?I o oai?eo ia AAeIE noaiiaeea a ia?oo iieiaeio e?eoaaiiy 1,4 iae, ca aanue ia??iae - 1,8 iae, oi i?e iia?e iaoiaeeoe? - 1,7208 iae. oa 2,1728 iae. ?I, ui a?aeiia?aeii ia 0,3208 oa 0,3728 iae. a?eueoa. O oai?eo ia OA A i?e cae/aei?e iaoiaeeoe? ??cieoey a i?aeaeuaii? iieaciee?a aacaeueiiai ??aiy ?I noaiiaeea 1,45 iae. ca iieiaeio e?eoaaiiy oa 2,25 iae. ?I i?e iiaiiio eo?n?, i?e iia?e iaoiaeeoe? - 2,2036 iae. oa 1,5170 iae. ?I, ui ia 0,7536 iae. ?I a?eueoa o ia?o?e iieiaei? e?eoaaiiy oa o?ioe iaioa ca aanue ia??iae. Uiaei iieaciee?a EI, oi i?e cae/aei?e iaoiaeeoe? i?eeiio IA aiia c?inoaea o oai?eo ia AAeIE ca ia?oo iieiaeio e?eoaaiiy ia 1,6 iae, ca aanue ia??iae ia 1,5 iae, i?e cai?iiiiiaai?e iaie - ia 2,14 oa 1,65 iae. ?I a?aeiia?aeii, oiaoi ia 0,54 oa 0,15 iae. ?I a?eueoa. O oai?eo ia OA A i?e cae/aei?e iaoiaeeoe? EI c?inoaea ia 1,1 oa 1,3 iae. ?I, i?e iia?e iaoiaeeoe? - ia 2,58 ? 1,76 iae. ?I a?aeiia?aeii, oiaoi ia 0,46 oa 1,48 iae. ?I a?eueoa. AAIIA na?aaeiuei? i?ia?ae?caoe?? “Iieyia Eaaniaa” i?e i?eeii? ?? ca cai?iiiiiaaiith iaie iaoiaeeeith i?iyaey? o oai?eo AAeIE oa OA A o oac? ?ai?n?? ae?aaeaiee e?eoaaeueiee aoaeo, yeee aecia/a?oueny o nooo?aiio iie?auaii? ee?i?/iiai noaio, cieaeaii? iieaciee?a ?aieiaiai aacaeueiiai oa i?/iiai ??aiia eeneioiino? oeoieiaiai nieo, ca iieacieeaie ?I o?ea, oa cia/iiio i?aeaeuaii? ??aiy ?I o aio?aeueiiio a?aeae?e? oeoieo. A?eueo ae?aaeaia i?aeaeuaiiy iieaciee?a aacaeueiiai ??aiy, iaeneiaeueiiai ??aiy ?I o?ea i?ney ia?i?aeueiiai i?eeiio 200 ie IA oa ?I aio?aeueiiai a?aeae?eo oeoieo o aeuaaeacaieo a?oi oai?eo a?aeaoeiny ca ia?oo iieiaeio naiaoi?ii-eo?i?oiiai e?eoaaiiy, i?ae ca ae?oao, ? iaaeeaeaeiny aei ci?i i?ioyaii onueiai iiaiiai eo?no e?eoaaiiy. A??ia?aeia i?aeaeuaiiy iieaciee?a EAI?I ia i?ii?aeeao /ano c a?ia?aoeeaei?noth o oai?eo ia AAeIE oa OA A ianooieei oaeiae aaea i?ney aeaaiaaeoeyoeaeaiiiai ia?aaoaaiiy a naiaoi???. O oai?eo ia OA A+A e?eoaaiiy IA ca cai?iiiiiaaiith iaie iaoiaeeeith ?? aioo??oiueiai i?eeiio ia aieeaa? ia iieacieee ?I. I?e aea/aii? iaoai?ci?a ae?? IA ia ?ioaeoe?th I? c’yniaaii, ui e?euee?noue oai?eo ia AAeIE oa OA A, ?io?eiaaieo I?, noaiiaeea 89%. A e?ioe? eo?no e?eoaaiiy IA I? aoa ae?aaiinoiaaiee o 55% oai?eo, a /a?ac i?nyoeue-i?aoi?a - o 40% oai?eo, o yeeo i?iaiaeeeiny iiaoi?ia aeine?aeaeaiiy. I?Ia iniia? io?eiaieo ?acoeueoao?a iiaeia neacaoe, ui aaeeea e?euee?noue I?-iiceoeaieo oai?eo ia AAeIE oa OAA, ye? aoee iai?aaeai? ia naiaoi?ii-eo?i?oia e?eoaaiiy, na?ae/eoue i?i iaaaeaeaaoi?noue oa?ai??, yea i?iaiaeeeany ?i a ia??iae caaino?aiiy aai i?i ?a?ioaeoe?th ca oeae ia??iae C iaoith ioe?iee a?aeaeaeaieo ?acoeueoao?a aaeueiaieia?/iiai e?eoaaiiy oai?eo ia AAeIE oa OA A AAIIA “Iieyia Eaaniaa” c aeei?enoaiiyi cai?iiiiiaaii? iaie iaoiaeeee ?? aioo??oiueiai i?eeiio, uiiaeiaioa /a?ac i?a?ieo aoei i?iaaaeaii iiooiaa aieaooaaiiy oai?eo. Iniiaiee noa’?eoeaiee iieaciee caaino?aiiy aeine?aeaeoaaieo caoai?thaaiue – aieueiaee neiae?ii c’yaeany /a?ac 4 i?nyoe? o 9,6% oai?eo ia AAeIE oa 18,2% oai?eo ia OA A, a aei 6 i?nyoe?a - o 28,8% oa 45,6 % oai?eo a?aeiia?aeii. Aei 3 i?nyoe?a o aeiaeiiai c oai?eo iaio a?oi ia aeieeaee aoaeue-ye? nea?ae, ca aeeeth/aiiyi ia??iaee/ieo cae?ai?a o 4,8% oa 27,3% a?aeiia?aeii. AENIIAEE 1. O oai?eo ia ae?aceo aeaaiaaeoeyoeiaei? eeoee ?nio? i?aeaeuaia ?io?eiaai?noue Helicobacter pylori ye a oac? caaino?aiiy (a 92,3% aeiaaee?a), oae ? a oac? ?ai?n??. C ?ioiai aieo, o I?-iiceoeaieo oai?eo ?niothoue ianiaoeeo?/i? ii?ooaiiy ineoieia?/iiai noaoono, ye? i?iyaeythoueny i?aeaeuaiith aioo??oiueith iai?oaith, o?eaiaith, no?aoaie, iaiioeaiaaiith aiyceea?noth, ianei?noe/iith ioe?ieith ia?niaeoeae, neaioeoeeciii, iaaeia??ith aei iaaee/ii? aeiiiiiae, iaaiaaiai?noth o nia? oa a eiiiaoaioiino? ioi/oth/eo, a ii??aiyii? c? caei?iaeie ethaeueie. 2. Aeaeiiiainaoe?y iaoai?ci?a aaeaioaoe?? o oai?eo ia aeoiaeaiaeueio ae?aceo aeieea? aiane?aeie cia/iiai cieaeaiiy iieaciee?a ?I o?ea oa aio?aeueiiai a?aeae?eo oeoieo, ye aacaeueieo, oae ? i?/ieo o?iiieia?/ieo eiii’thoa?ieo aaee/ei, oa iayaiino? I?. I?e/iio, ii?ooaiiy iieaciee?a eeneioii?iaeoeoe?? ye aacaeueieo, oae ? i?/ieo, caeeoa?oueny aac ci?i ia i?ioyc? o?eaaeiai /ano, iaa?oue i?ney i?iaaaeaiiy aoaeoeaii? aioaoeeaeii? oa?ai??. 3. Ae?aaeai?noue i?ioean?a ii?ooaiiy i?/ii? eeneioii?iaeoeoe?? o oai?eo ia ae?aceo aeaaiaaeoeyoeiaei? eeoee ei?aeth? a caeaaeiino? a?ae /ano. ??cea cieaeaiiy iieaciee?a ?I o?ea oeoieo oai?eo niinoa??aa?oueny a ia?o?e iieiaei? ii/? ? a??ia?aeii a?ae??ciy?oueny, a ii??aiyii? c eiio?ieueiith a?oiith, a /aniaiio i?ii?aeeo a?ae 23.00 aei 00.40 o oai?eo ia aeoiaeaiaeueio ae?aceo o oac? caaino?aiiy oa a?ae 23.00 aei 00.20 o oac? ?ai?n??. Iaaiaee, o ae?oa?e iieiaei? ii/? o oai?eo ia iaioe/io ae?aceo a iaeaeaio oacao caoai?thaaiiy niinoa??aa?oueny cia/iee i?aeeii iieaciee?a ?I, ? aiie a??ia?aeii ia a?ae??ciythoueny a?ae aiaeia?/ieo o eiio?ieueii? a?oie in?a. 4. Aeeoa?aioe?eiaaia e?eoaaiiy oai?eo ia aeoiaeaiaeueio ae?aceo a oac? caaino?aiiy ?c i?ecia/aiiyi iiai?acieo, aceo?ii?oeeio oa iao?ii?aeacieo i?eaiaeeoue aei a?aaeeeaoe?? ?ioaeoe?? Helicobacter pylori a 87,5% aeiaaee?a, ? c?o/iei aeey oai?eo, aeicaiey? cieceoe caaaeueio aeico aioei?e?iaieo i?aia?ao?a. Aeaoaaoith, aea iaio aoaeoeaiith aioeaae?eiaaeoa?iith noaiith (83,3%) ? eiia?iaoe?y i?aia?ao?a aea-iieo, oao?aoeeee?io oa iao?ii?aeacieo. 5. O I?-iiceoeaieo oai?eo ia aeoiaeaiaeueio ae?aceo a oac? ?ai?n?? i?ecia/aiiy i?ia?aeueii? aiaee “Iieyia Eaaniaa” ii 150 ie /a?ac 1-1,5 oa 3 aiaeeie i?ney i?eeiio ?ae? i?iyaey? ae?aaeaio eeneioi?aaoethth/o oa aioeaae?eiaaeoa?io ae?th, i?e/iio eeneioinoi?aneaia ae?y i?ia?aeueii? aiaee i?iyaey?oueny aaea ia 8-12 aeaiue e?eoaaiiy a naiaoi???. 6. A ca’yceo c oei, ui oai?? ia ae?aceo aeaaiaaeoeyoeiaei? eeoee a ??ci? oace caoai?thaaiiy ? eeneioi- oa I?-caeaaeieie, a?aenooi? iaae?ei? aioe-I? oa aioaoeeaei? noaie oa?ai??, /anoi aeieeathoue iia?/i? i?iyae iina?aaeiee?a, aoaeaeenea a?ae?iea?aiiaoia iao???aa i?ia?aeueia aiaea “Iieyia Eaaniaa” i?iyaey? ae?aaeaio aioeaae?eiaaeoa?io oa eeneioi?aaoethth/o ae?th, ne?ae aeio?eioaaoeny i?eioeeio aoaiiino? i?e e?eoaaii? aeoiaeaiaeueii? ae?acee. I?AEOE*I? ?AEIIAIAeAOe?? 1. A ca’yceo c 100% aeyaeaiiyi I?-?ioaeoe?? o oai?eo ia AAeIE, ia ?aeiiaiaeo?oueny aeei?enoiaoaaoe i?e iaoneeaaeiaieo oi?iao oeueiai caoai?thaaiiy o?a?iaano?iaeoiaeaiineii?th c a?iin??th ia i?aaeiao aeyaeaiiy I?, a iaiaaeeoeny ia?iaaceaieie iaoiaeaie, iai?eeeaae, aecia/aiiyi aioe-I? ?ioiiaeiaoe?io G. 2. Aecia/aiiy i?/ii? aioo??oiueioeoieiai? ?I c aeiiiiiaith EAI?I aeicaiey? io?eiaoe aeiaeaoeia? ia’?eoeai? aeai? i?i nooi?iue c?ooaiue a nenoai? eeneioii?iaeoeoe?y-eeneioiiaeo?ae?caoe?y oeoieo oai?eo ia AAeIE c iaoith aeai?o iaoiaeo oa eiio?ieth e?eoaaiiy. 3. Aeioe?eueii aecia/aoe nooi?iue ineoieia?/ieo c?ooaiue oai?eo ia AAeIE c aeei?enoaiiyi oanoo II?? c iaoith aeeth/aiiy a noaie e?eoaaiiy iaiao?aeieo iina?aaeiee?a, iacaeaaeii a?ae anioe?aoe?? c I? oa aoaio e?eoaaiiy. 4. Ia noaoe?iia?ii-iie?ee?i?/iiio aoai? e?eoaaiiy AAeIE aeioe?eueii aeei?enoiaoaaoe aenieiaoaeoeaio, ei?ioeino?ieiao, a?aeiinii aeaoaao eiia?iiaaio noaio c aeeth/aiiyi iiai?acieo (40 ia 1 ?ac ia aeaiue), yeee i?eeiathoue i?ioyaii oeaeiy, aceo?iiioeeio (500 ia 1 ?ac ia aeaiue) oa iao?iiiaeacieo (500 ia 3 ?ace ia aeaiue). Aeaa inoaii? i?aia?aoe i?eeiathoue c 5 aeiy e?eoaaiiy ia i?ioyc? 3 aeiia. 5. Aeioe?eueii aeio?eioaaoeny i?eioeeio aoaiiino? e?eoaaiiy oai?eo ia AAeIE c iai?aaeaiiyi ?o a naiaoi??? c AAIIA oeio “Iieyia Eaaniaa” c iaoith iie?auaiiy eeneioi?aaoeyoe?? a aano?iaeoiaeaiaeuei?e cii? oa inoaoi/ii? ae?i?iaoe?? I?. I?e oeueiio aeaio IA ia naiaoi?ii-eo?i?oiiio aoai? e?eoaaiiy oai?eo ia AAeIE ?aeiiaiaeo?oueny i?eeiaoe ca cai?iiiiiaaiith iaie iaoiaeeeith: ii 150 ie oaiei?, a?ey 40°N, aeaaaciaaii? IA /a?ac 1-1,5 oa 3 aiaeeie i?ney i?eeiio ?ae? - anueiai 6 ?ac?a ia aeaiue. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. ?eueei A.A. No/ani? i?eioeeie oa iiaeeeaino? iaoiaaiaoe/iiai e?eoaaiiy ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee // Iaoeiaee a?niee Oaeai?iaenueeiai oi?aa?neoaoo. – 1996. – Aei.3. – N.192-195. 2. ?eueei A.A., *iiae ?.A., Aa?aaeue A.?. Aieea i?ia?aeueii? aiaee “Iieyia Eaaniaa” ia i?ioeane eeneioiooai?aiiy oa iaeo?ae?caoe?? o oeoieo i?e iia?e iaoiaeeoe? ?? i?eeiio // Iaaeeoeeineay ?aaaeeeoaoeey, eo?i?oieiaey, oeceioa?aiey.- 1998.- ?2 (14). – N.26-30. 3. ?eueei A.A., *iiae ?.A., Aa?aaeue A.?. Aaeueiaieia?/ia e?eoaaiiy oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee oa o?ii?/i? aano?eoe i?e iia?e iaoiaeeoe? i?eeiio i?ia?aeueii? aiaee “Iieyia Eaaniaa” // Iaoeiaee a?niee Oaeai?iaenueeiai oi?aa?neoaoo. – 1998. – Aei.5. – N.90-93. 4. Aae?eiaaeoa??ice – ?noi??y aeine?aeaeaiiy. Aeaye? ieoaiiy ai?aeai?ieia?? oa cia/aiiy a naiaoi?ii-eo?i?oieo caeeaaeao / *iiae ?.A., Ieine?ia A.TH., A?ai?? I.I., A?aoanthe A.I., ?eueei A.A. // Iaoeiaee a?niee Oaeai?iaenueeiai oi?aa?neoaoo. – 1998. – Aei.5. – N.202-204. 5. Aeeoaeueiee oano ii aecia/aiith Helicobacter pylori – iaeaooi? iaoeiaeo aeine?aeaeaiue a naiaoi??yo aano?iaioa?ieia?/iiai i?io?eth / *iiae ?.A., ?eueei A.A., Aa?aaeue A.?., Iaaeee TH.TH., Naea?ao A.I., Iaae? TH.?.// Iaoeiaee a?niee Oaeai?iaenueeiai oi?aa?neoaoo. – 1998. – Aei.6. – N.194-197. 6. Aeei?enoaiiy ?I-iao??? a naiaoi?ii-eo?i?oiiio e?eoaaii? ia no/aniiio aoai? / ?eueei A.A., *iiae ?.A., Aa?ao I.I., Ieine?ia TH.TH., Eai/?e A.I., ?oaoeiaa ?.?. // No/ani? i?iaeaie ?ae?aaoe?? ia eo?i?oao ea?iaonueeiai ?aa?iio: Ca??iee iaoeiaeo i?aoeue. - Oaeai?iae, 1995. - N.104-106. 7. ?eueei A.A., *iiae ?.A., Aa?aaeue A.?. Ioe?iea aoaeoeaiino? e?eoaaiiy oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee oa o?ii?/iee aano?eo A iaoiaeii aecia/aiiy aioe-I? ?ioiiaeiaoe?io G // Iaoa?. ? Iaoe?iiaeueiiai Eiia?ano o?c?ioa?aiaao?a ? eo?i?oieia?a Oe?a?ie “O?ce/i? /eiieee a iaaee/i?e ?aaa?e?oaoe??” (i. Oi?eueiee, 13-14 o?aaiy 1998 ?ieo). Aeiaeaoie aei aeo?iaeo “Iaaee/ia ?aaa?e?oaoe?y, eo?i?oieia?y, o?c?ioa?ai?y” ?1, 1998. – 1998.- N.131-132. 8. *iiae ?.A., ?eueei A.A. I?i ia?iaeo aeaieo ?I-iao??? // Iaoa?. neiiiceoio “Aeooaeuei? ieoaiiy ?aaa?e?oaoe?? aano?iaioa?ieia?/ieo oai?eo” (*a?i?aoe?, 17-18 ea?oiy 1996 ?ieo). - *a?i?aoe?, 1996. - N.397-399. 9. I?i aeaye? iniaeeaino? i?io?eaiiy ae?aceiai? oai?iae oeoieo o i?aoe?aiee?a cae?cie/iiai o?ainii?oo / *iiae ?.A., ?eueei A.A., Aa?ao I.I., Eaaea? A.TH., Eieoaa A.?., Aa?/a? A.I., Ei?aeiaa N.A.// Iaoa?. eiioa?aioe?? “Aeooaeuei? i?iaeaie iaaee/iiai ianeoaiaoaaiiy i?aoethth/eo ia cae?cie/iiio o?ainii?o?” (Oaeai?iae, 12-14 /a?aiy 1996 ?ieo) - Oaeai?iae, 1996.- N.99-100. 10. Oa?aeoa? ci?i aa?oi?o ? ieaei?o a?aeae?e?a o?aaiiai eaiaeo o oai?eo iioeeiai a?eo / *iiae ?.A., Aa?aaeue A.?., ?eueei A.A., Ieine?ia TH.TH., Oo?yieoey I.A., Iaae? TH.?., *eaeia I.A., Naea?ao A.I., Aieiaaie/ I.E., Ieine?ia A.TH., Aaiaaeee I.?., Eieoaa A.?. // Iaoa?. Ieaioio I?aae?iiy Oe?a?inueeiai oiaa?enoaa aa?iioieia?a oa aa??ao??a “O?c?ieia?y ? iaoieia?y i?aai?a o?aaeaiiy o in?a iioeeiai ? noa?a/iai a?eo” (*a?i?aoe?, 18-20 aa?aniy 1996 ?ieo).- *a?i?aoe?, 1996.-N.137. 11. The treatment of the Helicobacter pylori infection by hydrocarbonate natrium borate mineral waters / Ilko A.V., Chopey I.V., Gergel V.I., Lemko I.S., Korshinska M.I.// 8th International Congress on Infectious Diseases (Boston, Massachusetts, USA, May 15-18, 1998) – 1998. - P.135. 12. Bacteriological and endoscopic investigations of the bowels with acute diarrhea / Chopey I.V., Turyanitsa S.M., Ilko A.V., Gergel V.I., Ploskina Y.Y., Ploskina V.Y., Nesterchuk A.A.// 8th International Congress on Infectious Diseases (Boston, Massachusetts, USA, May 15-18, 1998) – 1998. - P.43. AIIOAOe?ss ?eueei A.A. Iaoiaaiaoe/ia iaa?oiooaaiiy aoaiiiai e?eoaaiiy aeoiaeaiaeueii? ae?acee, anioe?eiaaii? c Helicobacter pylori. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02 – aioo??oi? oai?iae. - Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC Oe?a?ie, Ee?a, 1999. Aeena?oaoe?y i?enay/aia iaoeiaiio iaa?oiooaaiith aoaiiiai e?eoaaiiy ae?acee aeaaiaaeoeyoeiaei? eeoee ia iniia? aea/aiiy ?io?eiaaiino? Helicobacter pylori, iieaciee?a eeneioii?iaeoeoe?? oa eeneioiiaeo?ae?caoe??, a oiio /ene? i?/iiai iii?oi?oaaiiy ?I oeoieo, aioeaae?eiaaeoa?ieo noai a aiaoeaoi?ii-noaoe?iia?ieo oa naiaoi?ii-eo?i?oieo oiiaao. Ianoaaeaii 125 oai?eo ia aeoiaeaiaeueio ae?aceo. C’yniaaii, ui iaioe/ia ae?acea ? eeneioi- oa I?-caeaaeiith, aioe-I? iaoiaee aecia/athoueny aoaiii e?eoaaiiy. Aeei?enoaiiy eiii’thoa?iiai iii?oi?oaaiiy ?I aeicaieeei iioei?coaaoe oeyoe ei?aeoe?? iieaciee?a aacaeueii? oa i?/ii? nae?aoe?? oeoieo oa ?aeiiaiaeoaaoe iiaee ieoiee i?eeii i?ia?aeueii? aiaee “Iieyia Eaaniaa”. Eeth/ia? neiaa: ae?acea aeaaiaaeoeyoeiaei? eeoee, Helicobacter pylori, eiii’thoa?iee aioo??oeoieiaee iii?oi?eia ?I, eeneioii?iaeoeoe?y, eeneioiiaeo?ae?caoe?y, i?ia?aeueia aiaea. SUMMARY Ilko A.V. Pathogenetic substuntiation of multistage treatment Helicobacter pylori associate duodenal ulcer. – Manuscript. Thesis for a candidate’s degree by speciality 14.01.022 – internal diseases. – Kyiv Medical Academy of Post-Graduated Education named after P.L.Shupyk Health Ministry of Ukraine, Kyiv, 1999. The dissertation is devoted to the scientific substuntiation of the treatment of duodenal ulcer, based on the study of the infected Helicobacter pylori, indices of acid production and acid neutralization, including night ?H- monitoring of a stomach, anti-HP schemes in the policlinics-hospitals and sanatoriums. 125 patients with duodenal ulcer were investigated. We found that peptic ulcer is depending on acids and HP, anti-HP methods are being determined by the stage of treatment. The usage of the computer ?H-monitoring made possible to optimize the ways of correction the indices of basal and night secretion of the stomach; it made possible to recommend the new method of the “Polyana Kvasova” mineral water drinking. Key words: duodenal ulcer, Helicobacter pylori, computer pH-monitoring, acid production, acid neutralization, mineral water. AIIIOAOeEss Eeueei A.A. Iaoiaaiaoe/aneia iainiiaaiea yoaiiiai ea/aiey aeoiaeaiaeueiie ycau, annioeee?iaaiiie n Helicobacter pylori. – ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02 – aioo?aiiea aieacie. - Eeaaneay iaaeeoeeineay aeaaeaiey iineaaeeieiiiiai ia?aciaaiey ei. I.E.Ooieea IC Oe?aeiu, Eeaa, 1999. Aeenna?oaoeey iinayuaia iao/iiio iainiiaaieth yoaiiiai ea/aiey ycau aeaaiaaeoeaoeia?noiie eeoee ia iniiaaiee eco/aiey eioeoee?iaaiiinoe Helicobacter pylori (I?), iieacaoaeae eeneioii?iaeoeoeee e eeneioiiaeo?aeecaoeee, a oii /enea ii/iiai iiieoi?e?iaaiey ?I aeaeoaeea, aioeaaeeeiaaeoa?iuo noai a aiaoeaoi?ii-noaoeeiia?iuo e naiaoi?ii-eo?i?oiuo oneiaeyo. Ianeaaeiaaii 125 aieueiuo aeoiaeaiaeueiie ycaie, 30 aieueiuo o?iie/aneei aano?eoii A e 77 eeoe eiio?ieueiie a?oiiu. Auyniaii, /oi iaioe/aneay ycaa aeaaiaaeoeaoeia?noiie eeoee yaeyaony eeneioi- e I?-caaeneiie, i?e/ai eioeoee?iaaiiinoue I? eae a oaca iaino?aiey, oae e ?aiennee i?eaeeceoaeueii iaeeiaeiaay e ano?a/aaony i?aeoe/anee o eaaeaeiai aieueiiai. A ?aaioa aeeneooe?othony aii?inu ?iee e iaoaieciia ia?ooaiey eeneioii?iaeooee?othuae ooieoeee aeaeoaeea o aieueiuo iaioe/aneie ycaie, eioi?ay, ii iieacaoaeyi ?I, oa?aeoa?ecoaony a aieueoeinoaa neo/aaa aeaeiiiainaoeeae iaoaieciia aaeaioaoeee eae aacaeueiie, oae e ii/iie nae?aoeee. I?e/ai ?aceia nieaeaiea ii/iuo iieacaoaeae ?I oaea aeaeoaeea oaeeo aieueiuo eae a oaca iaino?aiey, oae e ?aiennee aeinoiaa?ii ioee/aaony ii n?aaiaieth n eiio?ieueiie a?oiiie aeeaea e iieoii/e. Ai aoi?ie iieiaeia ii/e o aieueiuo aeoiaeaiaeueiie ycaie a iaaeo oacao caaieaaaiey iaaethaeaaony cia/eoaeueiue iiaeuai iieacaoaeae ?I e iie ia ioee/athony io oaeiauo o i?aeoe/anee caei?iauo eeoe. N ae?oaie noi?iiu, e?iia yoeo iniiaiuo iaoaieciia oeueoea?iaaiaca, o I?-iieiaeeoaeueiuo aieueiuo ycaie aeaaiaaeoeaoeia?noiie eeoee iaaethaeathony ianiaoeeoe/aneea ia?ooaiey ineoieiae/aneiai noaoona. A ?aaioa aiaeece?oaony yooaeoeaiinoue ?yaea noai aioeaaeeeiaaeoa?iie oa?aiee a oaca iaino?aiey aeoiaeaiaeueiie ycau. Onoaiiaeaii, /oi eiiaeiaoeey iiai?aciea, aceo?iieoeeia e iao?iieaeaciea yaeyaony iaeaieaa yooaeoeaiie, a oi a?aiy eae eiiaeiaoeey aea-iiea, oao?aoeeeeeia e iao?iieaeaciea yaeyaony aieaa auaiaeiie n yeiiiie/aneie oi/ee c?aiey. Ianoaeaeaiu iiai/iua yooaeou enneaaeoaiuo iaaeeeaiaioiciuo noai, i?e/ai iie auee ieieiaeueiuie e iaia?oaeeaaeenue o iacia/eoaeueiiai eiee/anoaa aieueiuo. Iieacaii, /oi eniieueciaaiea eiiiuthoa?iiai iiieoi?e?iaaiey ?I iicaieyao iioeiece?iaaoue iooe ei??aeoeee aaee/ei aacaeueiie e ii/iie nae?aoeee aeaeoaeea e ?aeiiaiaeiaaoue iiaue ieoueaaie i?eai ieia?aeueiie aiaeu “Iieyia Eaaniaay” ia naiaoi?ii-eo?i?oiii yoaia ea/aiey. Onoaiiaeaii, /oi oaeaeeneay aeae?iea?aiiaoiay iao?eaaay ieia?aeueiay aiaea n?aaeiae ieia?aeecaoeee “Iieyia Eaaniaay” i?e i?eaia aa ii i?aaeeaaaaiie a ?aaioa iaoiaeeea i?iyaeyao o aieueiuo aeoiaeaiaeueiie ycaie e o?iie/aneei aano?eoii A a oaca ?aiennee au?aaeaiiue ea/aaiue yooaeo, eioi?ue ii?aaeaeyaony a nouanoaaiiii oeo/oaiee eeeie/aneiai ninoiyiey, nieaeaiee iieacaoaeae oo?aiiaai aacaeueiiai e ii/iiai o?iaiae eeneioiinoe aeaeoaei/iiai niea, ii iieacaoaeyi ?I oaea, e cia/eoaeueiii oaaee/aiee o?iaiy ?I a aio?aeueiii ioaeaea aeaeoaeea. Aieaa au?aaeaiiia iiauoaiea iieacaoaeae aacaeueiiai o?iaiy, iaeneiaeueiiai o?iaiy iinea ia?i?aeueiiai i?eeiia 200 ie ieia?aeueiie aiaeu e ?I aio?aeueiiai ioaeaea aeaeoaeea o ianeaaeiaaiiuo a?oii aieueiuo i?ienoiaeeo a ia?aoth iieiaeio naiaoi?ii-eo?i?oiiai ea/aiey, /ai ai aoi?oth, e i?eaeeaeaaony e eciaiaieyi ia i?ioyaeaiee anaai iieiiai eo?na aaeueiaieiae/aneie oa?aiee. I?e eco/aiee aicaeaenoaey ieia?aeueiie aiaeu “Iieyia Eaaniaay” ia eioaeoeeth I? auyniaii, /oi iinea eo?na ea/aiey yoie ieia?aeueiie aiaeie eiee/anoai I?-eioeoee?iaaiiuo aieueiuo oiaioeeinue a aeaa ?aca. A nayce n oai, /oi aieueiua ycaie aeaaiaaeoeaoeia?noiie eeoee yaeythony eeneioi- e I?-caaeneiuie, ionoonoaotho iaaeaaeiua aioe-I? e aioaoeeaeiua noaiu oa?aiee, eiiaaea aicieeatho iiai/iua i?iyaeaiey iaaeeeaiaioia, a oi a?aiy eae oaeaeeneay aeae?iea?aiiaoiay iao?eaaay ieia?aeueiay aiaea “Iieyia Eaaniaay” i?iyaeyao ae?aaeaiiia aioeaaeeeiaaeoa?iia e eeneioi?aaoee?othuaa aeaenoaea, iaiaoiaeeii i?eaea?aeeaaoueny i?eioeeia yoaiiinoe a ea/aiee aieueiuo aeoiaeaiaeueiie ycaie. Eeth/aaua neiaa: ycaa aeaaiaaeoeaoeia?noiie eeoee, Helicobacter pylori, eiiiuthoa?iue aioo?eaeaeoaei/iue iiieoi?eia ?I, eeneioii?iaeoeoeey, eeneioiiaeo?aeecaoeey, ieia?aeueiay aiaea.

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