4

OA?E?ANUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

*A?EANIAA Ieueaa A?eai??aia

OAeE 616.127-005.8-036.11-035-085.384:547.221

INIAEEAINO? IA?AA?AO ?IOA?EOO I?IEA?AeA I?E

AEEI?ENOAII? IAOOI?AIO

14.01.11 — ea?ae?ieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Oa?e?a — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia ia eaoaae?? oaeoeueoaonueei? oa?ai?? oa aiaeie?eiieia??
Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii? aeaaeai??.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

i?ioani? Ia?oeaaa Oaoyia
Ieaen??aia,

Aei?i?iiao?ianueea aea?aeaaia
iaaee/ia aeaaeai?y,

caa?aeoaa/ eaoaae?ith
oaeoeueoaonueei? oa?ai?? oa aiaeie?eiieia??.

Io?oe?ei? iiiiaioe:

caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie, aeieoi? iaaee/ieo iaoe,

i?ioani? Eaoiaoc ?aai E?iae?aoiae/, Oa?e?anueeee aea?aeaaiee iaaee/iee
oi?aa?neoao,

caa?aeoaa/ eaoaae?ith aioo??oi?o oai?ia, nii?oeaii? iaaeeoeeie ? EOE,

eaiaeeaeao iaaee/ieo iaoe, aeioeaio Oonoaaeue Ieeiea Oaaei?iae/,
Oa?e?anueeee ?inoeooo oaeineiiaeaiiy e?ea??a, caa?aeoaa/ eaoaae?ith
ea?ae?ieia?? ? ooieoe?iiaeueii? ae?aaiinoeee.

I?ia?aeia onoaiiaa:

Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo ea?ae?ieia?? ?iai? aeaaeai?ea
I.Ae.No?aaeanea, a?aeae?eaiiy ?aai?iaoe?? oa ?ioaineaii? oa?ai??, IIC
Oe?a?ie (i.Ee?a).

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 8 ” ea?oiy 1999 ?. i 13-30 aiaeei?

ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.600.04 o Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? (310022, i.Oa?e?a, i?.Eai?ia,4).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (310022, i.Oa?e?a, i?.Eai?ia,4).

Aaoi?aoa?ao ?ic?neaiee “5” aa?aciy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeioeaio, e.i.i.
Ia/a?aiei E.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. ?ioa?eo i?iea?aea (?I) ? iaei??th c iniiaieo i?e/ei
nia?oiino? oa ?iaae?aeecaoe?? iaoe??io?a ?c caoai?thaaiiyie
na?oeaai-noaeeiii? nenoaie (*acia A.E., 1992, Aic?aiia I.O.,1996). Ca
aeaieie aenia?o?a ?iai/i? a?oie ?a?iiaenueeiai oiaa?enoaa ea?ae?ieia?a
(Sans S., Keselot H. et al., 1998), nia?oi?noue a?ae ?I a Oe?a?i? cia/ii
aeua, i?ae a ?ioeo ?a?iiaenueeeo e?a?iao, ui iia??oo? caaaeueiee noai
caei?ia’y iaoe?? a oe?eiio ? i?eiineoue cia/i? aeiiii?/i? caeoee.

Ai?iaaaeaeaiiy a i?aeoeeo aeaieo ooiaeaiaioaeueieo aeine?aeaeaiue,
iaea?aeaieo ai?iaeiaae inoaii?o ?ie?a, aeicaieeei ?noioii cieceoe
e?ea?iyio eaoaeuei?noue ? iie?aueoe i?iaiic i?e oeueiio caoai?thaaii?
(Aioiiaiei E.I. ? ni?aaao., 1995; Iaea E.O., Aeeeoi ss.A., 1995). Iaeiae
iiooe iiaeo i?aeoiae?a aei e?eoaaiiy ?I caeeoa?oueny aeooaeueiith
i?iaeaiith.

Aeiaaaeaii, ui iniiaiith aeaoa?i?iaioith nia?oiino? a?ae ?ioa?eoo
neoaeeoue ?ici?? ooeiaeaeaiiai i?iea?aea, ui e iaoiiaeei ?ic?iaeo
iaoiae?a, ni?yiiaaieo ia eiai caoeno oeyoii ciaioaiiy niiaeeaaiiy iei
eenith, aai ae a?aeiiaeaiiy ia?ooc?? a ?oai?ciaaieo
oeaieiao(Braunwald E., 1988; Yusuf S.,1987). Inue /iio iiyaa i?aia?aoa,
caeaoiiai iie?aueoe aeinoaaeo eenith aei i?iea?aeo ? aiaeii/an cieceoe
iio?aao a iueiio, aeeeeeaea ?ioa?an. Oea iaaaiiaeia?iiaee ia?aiiniee
eenith — ia?ooi?ai, 10 ia.% noai?e?iiia aioeuen?y ia iniia?
ia?ooi?aoaeaoeaaeo niieoe ?c aacio?ainii?oiith ooieoe??th (Ai?iaueaa
N.E., 1997), ui aea? i?eioeeiiai iiao iiaeeea?noue i?ae?eoe aei i?iaeaie
e?ea?aeaoe?? a?iien??, ye iaeiiai c iaoio?c?ieia?/ieo iaoai?ci?a
oi?ioaaiiy ? ?icaeoeo iaiai?ioieo ci?i a i?iea?ae?.

Iaaeeei-a?ieia?/ia canoinoaaiiy ia?ooi?aoaeaoeaaeo aioeuen?e
aecia/a?oueny ?o caeaoi?noth aei aacio?ainii?oo (Eaaieoeeee A.?. e
niaao., 1993, 1995), yea iaoiiaeaia, ii-ia?oa, aaciina?aaei?i
o?ainii?oii eenith oa aoaeaeeneiai aaco i?iii?oe?eii aei ia?aiaaeo ?o
iai?oaeaiiy, ii-ae?oaa, iineeaiiyi iioie?a aac?a aiane?aeie c?inoaiiy ?o
ianiia?aiino i?ae a?eo?ioeeoaie ? oeaieiaie (Ai?iaueaa N.E., e niaao.,
1989, Eaaiia E.I., 1987, Eneaiia A.E, 1991, Aieoaaa A.I., 1993);
ii-o?ao?, ooai?aiiyi aeiaeaoeiai? ?ieino? aeey eenith a ieaci?
(aeaiioa?a) (Eociaoeiaa E.I., 1993, 1997). Ia i?aenoaa? ia?aeiieeaeo
aenia?eiaioaeueieo aeine?aeaeaiue(Eneaiia A.E. e niaao., 1987, 1991),
aoei aeiaaaeaii caeaoi?noue ia?ooi?aoaeaoe?a caaaeyee nai?i iaeei
?ici??ai (0,1iei) i?ioiaeeoe eai?ey?e, iai?io?aei? aeey a?eo?ioeeo?a
/a?ac iaa?ye oeaiei, niaci i?aeai?ey?ieo no?ieoa??a, caeoii?eo eai?ey??a
a?iiene/ieie a?eo?ioeeoaie. E??i oiai, a aenia?eiaioaeueieo ?iaioao
(Ai?iaueaa N.E., Iaaaneee A.E. 1989, Eneaiia A.E., 1991) a?aecia/aii
ca?eueoaiiy ei?iia?iiai e?iaiia?ao aiane?aeie cieaeaiiy a’yceino? e?ia?,
yea aeinoia??ii ciaioo?oueny aaciina?aaeiuei i?ney oaaaeaiiy ia?ooi?aio.

C?inoaiiy i?iieeiino? ee?oeiieo iaia?ai i?e ?oai?? — iaeei c iniiaieo,
eiee ia ae??oaeueiee oaeoi?, ui iineeth? iioeiaeaeaiiy ee?oei. Aaaaeaiiy
ia?ooi?aoaeaoeaaeo aioeuen?e noi?iaiaeaeo?oueny oei/aniaei iaeiie/aiiyi
i?i?iaeueieo ?o e?eueeinoae a na?eiieaciaoe/ieo iaia?aiao
ea?ae?ii?ioeeo?a, iiaeeo?eoth/e iaia?aie ee?oei, oei naiei ciaiooth/e
?oai?/i? ? ?aia?ooc?ei? iioeiaeaeaiiy i?iea?aea (Forman M.B. et al.,
1992).

Oaeei /eiii, ?aeay i?i aeioe?euei?noue aeei?enoaiiy ia?ooi?aio i?e
?oai?/ieo o?aaeaiiyo i?iea?aea (Aaeiy?oeaa O.O., 1980) ao?ethaaeany
caeaa?eueoiai a aenia?eiaioaeueieo ?iaioao (Eaaeeeia TH.A. e niaao.,
1991, 1992). A ie?aieo ?iaioao ii eiai aeei?enoaiith i?e ?I a ee?i?oe?
iieacaii ni?eyoeeaee aieea ia oeaio?aeueio aaiiaeeiai?eo, ciaioaiiy
?eceeo o?iiaiooai?aiiy ? iie?ioaiiy ?aieia?? e?ia? (Aeeaa I.I. e niaao.,
1997). I?ioa oea niinoa?aaeaiiy ia aea? iiaii? oyae i?i aieea ia?ooi?aio
ia ?ici??e ina?aaeeo iae?ico, iniaeeaino? ee?i?/iiai ia?aa?ao ?I a
?aiiueiio ? a?aeaeaeaiiio ia??iaeao, ui e niiioeaei ian i?iaanoe aeaia
aeine?aeaeaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa aoea
aeeiiaia ye o?aaiaio ieaiiai? iaoeiai-aeine?aeii? ?iaioe “?ic?iaeoe
oaoiieia?th aeei?enoaiiy iaaaiiaeia?iiaiai ia?aiinieea eenith —
ia?ooi?aio — i?e e?eoe/ieo noaiao a oiiaao aenia?eiaioo ? ee?i?ee”
(?a?no?aoe?eiee oeo? aeiaiai?o ii IIC Oe?a?ie OeO 406).

Iaoa ? caaea/? aeine?aeaeaiiy. Iaoa ?iaioe — iaoeiai iaa?oiooaaoe
iiaeeea?noue ? aeioe?euei?noue aeei?enoaiiy iaaaiiaeia?iiaiai
ia?aiinieea eenith — ia?ooi?aio — a eiiieaeni?e oa?ai?? aino?iai
ia??iaeo ?ioa?eoo i?iea?aea oeyoii ioe?iee ?acoeueoao?a e?eoaaiiy a
iaeaeeae/iio ? a?aeaeaeaiiio ia??iaeao.

Aeey aeinyaiaiiy iaoe aoee iinoaaeai? oae? caaea/? aeine?aeaeaiiy:

1.Aecia/eoe iniaeeaino? ee?i?/iiai ia?aa?ao ?ioa?eoo i?iea?aea i?ney
aeei?enoaiiy ia?ooi?aio.

2.Ioe?ieoe aaee/eio ciie iae?ico ? aecia/eoe aeeiai?eo a?iaeaeo?e/ieo
ci?i a i?iea?ae? o oai?eo ia ?ioa?eo i?iea?aea a i?ioean? eiiieaeniiai
e?eoaaiiy ?c canoinoaaiiyi ia?ooi?aio ? aac iueiai.

3.C’ynoaaoe aeeiai?eo iieaciee?a neiiaoi-aae?aiaeiai?,
a?noai?ii?aaeoeaii? oa na?ioii?ia?a?/ii? nenoai o oai?eo ia ?ioa?eo
i?iea?aea a i?ioean? o?aaeeoe?eiiai e?eoaaiiy ? ia oe? aeei?enoaiiy
ia?ooi?aio.

4.Aea/eoe noai nei?ioii? caeaoiino? i?iea?aea o oai?eo ia ?ioa?eo
i?iea?aea i?ney i?iaaaeaiiai e?eoaaiiy c aeei?enoaiiyi ia?ooi?aio ? aac
iueiai.

5.I?iaanoe ?ao?iniaeoeaia niinoa?aaeaiiy oai?eo, ui ia?aianee ?ioa?eo
i?iea?aea, i?ney ??cieo aa??aio?a ii/aoeiai? oa?ai??.

Iaoeiaa iiaecia ?iaioe. O aeeiiai?e ?iaio? aia?oa a ee?i?oe? o oai?eo ia
?I a eiiieaen? ?ioaineaii? oa?ai?? aino?iai ia??iaeo aeei?enoaiee
iaaaiiaeia?iiaee ia?aiiniee eenith ia?ooi?ai. Aea/aii iniaeeaino?
ee?i?/iiai ia?aa?ao ?I i?ney aeei?enoaiiy i?aia?aoo. Ia i?aenoaa?
aea/aiiy aeeiai?ee aeaeo?io?c?ieia?/ieo iieaciee?a aeiaaaeaia
caeaoi?noue i?aia?aoo iaiaaeoaaoe i?iaiiciaaio ciio iae?ico. C’yniaaiee
iaoai?ci ni?eyoeeaiai aoaeoo, coiiaeaiiai caeaoi?noth ia?ooi?aio
ciaiooaaoe ?oai?th a ia?e?ioa?eoi?e cii? ? caaaeyee oeueiio ni?eyoe
caa?aaeaiith a?eueoi? e?eueeino? aeeoo?caeaoieo ea?ae?ii?ioeeo?a.
Aeyaeaii ciaioaiiy /enea ai?ciae?a o?aiceoi?ii? ?oai?? i?iea?aea ?
oeoii/eiaeo aeno?anenoie, a oiio /ene? a?oiiaeo ? aenieeo a?aaeaoe?e
(oeio R/T), o iaoe??io?a, ui iaea?aeaee ia?ooi?ai a eiiieaen?
?ioaineaii? oa?ai??. Iieacaii ciaioaiiy ii?ooaiiy ? i?enei?aiiy
aeeth/aiiy eiiiainaoi?ieo iiaeeeainoae neiiaoi-aae?aiaeiai?,
a?noai?ii?aaeoeaii? ? na?ioii?ia?a?/ii? nenoai i?e aeei?enoaii?
ia?ooi?aio. Anoaiiaeaiee ni?eyoeeaee aieea ?iooc?? ia?ooi?aio ia
iaeaeeae/? ? a?aeaeaeai? ?acoeueoaoe e?eoaaiiy.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

Cai?iiiiiaaia noaia eiiieaenii? oa?ai?? aino?iai ia??iaeo ?I c
aeei?enoaiiyi iaeii?aciai? ?iooc?? ia?ooi?aio a noia?i?e aeic? 4-5 ie/ea
aaae o?ea ni?eyea ciaioaiith ae?aaeaiino? aieueiaiai neiae?iio ia
ii/aoeo e?eoaaiiy, ui iiaea aooe iiyniaia ciaioaiiyi ??aiy a?iienai?? ?
oeaieiii? a?iien??. Oea i?aeoaa?aeaeo?oueny aea/aiiyi aeeiai?ee
iieaciee?a aac?a e?ia? ? eeneioii-iniiaiiai noaio. Aeiaaaeaii, ui
aeeth/aiiy ia?ooi?aio a eiiieaen ?ioaineaii? oa?ai?? ?I aaaea aei
ciaioaiiy ?ici???a e?ioeaai? ciie iae?ico, yea neeaea a oe?e a?oi?
oai?eo 17,4% o ii??aiyii? c 21% o a?oi?, ui eiai ia iaea?aeaea. I?e
oeueiio ia’?i caa?aaeaiiai i?iea?aea a ia?oiio aeiaaeeo noaiiaea 27%, a
a ae?oaiio — 12,5%. C’yniaaii, ui i?e aeei?enoaii? ia?ooi?aio a
eiiieaen? ?ioaineaii? oa?ai?? aino?iai ia??iaeo ?I oaeaeoa ? a?eueo
iiaii a?aeaoaa?oueny a?aeiiaeaiiy ooieoe?? i?iea?aea, ui aaaea aei
iaioi? ae?aaeaiino? oyaeeino? na?oeaai? iaaeinoaoiino? ye a ?aiiueiio,
oae ? o a?aeaeaeaiiio ia??iaeao. Anoaiiaeaii, ui o oai?eo, ui io?eiaee
ia?ooi?ai, oaeaeoa a?aeiiaeth?oueny aei o?c?ieia?/iiai ??aiy
ooieoe?iioaaiiy no?an-e?i?ooth/i? nenoaie i?e e?auiio caa?aaeaii? ??
?aca?a?a. Oea aea? i?aenoaao aaaaeaoe a?eueo aeioe?eueiei oi?ioaaiiy
aaeaioaoe?? o oe??? eaoaai??? oai?eo. Aecia/aii a?eueo iiaia
a?aeiiaeaiiy i?aoeacaeaoiino? o oai?eo, ui io?eiaee ia?ooi?ai a
eiiieaen? ?ioaineaii? oa?ai??, ui i?aeoaa?aeaeo?oueny ? a?eueoith
/anoioith iiaa?iaiiy ?o aei i?aoe?.

I?eeiyoa noaia ?ioaineaii? oa?ai?? c iaeii?aciaei aaaaeaiiyi ia?ooi?aio
iie?aueea ?acoeueoaoe e?eoaaiiy oai?eo a iaeaeeae/iio oa ?o noai o
a?aeaeaeaiiio ia??iaeao ?I. ?acoeueoaoe aeine?aeaeaiiy ai?iaaaeaeai? a
i?aeoeeo ?iaioe ?ioa?eoiiai ? ?aai?iaoe?eiiai a?aeae?eaiue EI OIAe
i.Aei?i?iiao?ianueea. Aeei?enoaiiy i?aia?aoo a eiiieaeni?e oa?ai??
noi?iaiaeaeo?oueny iie?auaiiyi naiiii/oooy oai?eo a ?aiiueiio
iino?ioa?eoiiio ia??iae? caaaeyee ciaioaiith i?iya?a aieueiaiai
neiae?iio oa e?ioeaaeo ?acoeueoao?a e?eoaaiiy, ui i?aeoaa?aeaeo?oueny
ciaioaiiyi i?iya?a na?oeaai? iaaeinoaoiino?. ?ic?aooiie aaee/eie
e?ioeaai? ciie iae?ico ca aeaieie AEA ? aecia/aiiy e?eueeino?
aacaieueiaeo ai?ciae?a ?oai?? i?iea?aea ca aeaieie oieoa??anueeiai
iii?oi?oaaiiy aeicaiey? nai?/anii ei?eaoaaoe oa?ai?th ? ciaioo? no?iee
ia?aaoaaiiy a ?ioa?eoiiio a?aeae?eaii?. A iaa/aeueiee i?ioean
Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii? aeaaeai?? ai?iaaaeaeai? aeai?
i?i aeiiiaiaiiy aei cania?a e?eoaaiiy ?I oa aeiaeaoeia? iiaeeeaino?
ioe?iee aoaeoeaiino? i?iaaaeaii? oa?ai?? ca aeaieie AEA, oieoa??anueeiai
iii?oi?oaaiiy AEA, aecia/aiiy aeiaiai? aene?aoe?? eaoaoieai?i?a.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii iniaenoi i?iaiae?ciaaia iaoeiaa
e?oa?aoo?a ca ia?aiith oaiaoeeith, i?iaaaeaiee ?ioi?iaoe?eiee iiooe.
Naiino?eii i?iaaaeaii ianoaaeaiiy oai?eo ca?aeii c i?ia?aiith
aeine?aeaeaiiy ia an?o eiai aoaiao. Ia?aeiia ? noaoenoe/ia ia?iaea
?acoeueoao?a aeine?aeaeaiue, iiaoaeiaa iaoaiaoe/ieo iiaeaeae i?ioean?a
caniaaie aa??aoe?eii? noaoenoeee, ui ?aae?coaaeeny noaiaea?oieie
iaeaoaie i?eeeaaeieo i?ia?ai noaoenoe/iiai aiae?co STADIA 4.0 ?
STATISTICA FOR WINDOWS 5.0, aeeiiai? aaoi?ii iniaenoi. Naiino?eii
i?iaaaeaiee aiae?c iaea?aeaieo aeaieo, noi?ioeueiaai? aeniiaee oa
i?aeoe/i? ?aeiiaiaeaoe??, ui aeo?eathoue c ?acoeueoao?a aeaiiai
aeine?aeaeaiiy.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aeiiia?aeaeeny ? iaaiai?thaaeeny ia IX ? O i?aeia?iaeieo neiiic?oiao ii
aea/aiith ia?ooi?aoaeaoeaaeo niieo/aiue a iaaeeoeei? ? a?ieia??
“Perfluorocarbon-96 oa -98” (Ioueii, ?in?y, 1996,1998), VI Eiioa?aioe??
na?oiai? Oaaea?aoe?? Oe?a?inueeeo e?ea?nueeeo oiaa?enoa (Iaeana, 1996),
II Iaoe?iiaeueiiio Eiia?an? aianoac?ieia?a Oe?a?ie (Oa?e?a, 1996),
can?aeaiiyo iaeanieo iaoeiaeo oiaa?enoa oa?aiaao?a (1997),
aianoac?ieia?a-?aai?iaoieia?a (1995, 1997) i.Aei?i?iiao?ianueea.
Ai?iaaoe?y aeena?oaoe?? a?aeaoeanue 16 aeiaoiy 1998 ?ieo ia ?icoe?aiiio
can?aeaii? eaoaae?e oaeoeueoaonueei? oa?ai?? oa aiaeie?eiieia??
Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii? aeaaeai??.

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 14 iaoeiaeo ?ia?o (3 c
ieo — a oeaio?aeueieo aeo?iaeao). 5 ?ia?o i?aeaioiaeai? naiino?eii, 9 —
o ni?aaaoi?noa?.

Ianya ? no?oeoo?a ?iaioe. Aeena?oaoe?y iaienaia a o?aaeeoe?eiiio noee? ?
neeaaea?oueny ?c anooio, iaeyaeo e?oa?aoo?e, 6 ?icae?e?a aeanieo
niinoa?aaeaiue, caeeth/aiiy, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e.
Iaoa??ae aeeeaaeaii ia 175 noi??ieao, ?ethno?iaaii 29 oaaeeoeyie ? 33
?enoieaie, ui noaiiaeoue 31 noi??ieo. A?ae?ia?ao?y aeeth/a? 146 ?ia?o
a?o/eciyieo ? 82 — ca?oa?aeieo aaoi??a, ui neeaaea? 29 noi??iie.

INIIAIA *ANOEIA

Ee?i?/ia oa?aeoa?enoeea oai?eo. Ianoaaeaii 82 oai?eo c ia?oei ?I,
/ieia?e?a, a?eii a?ae 38 aei 60 ?ie?a, ui iaae?eoee i?ioyaii ia?oeo 6
aiaeei a?ae ii/aoeo aieueiaiai i?enooio ? ciaoiaeeeenue ia e?eoaaii? o
a?aeae?eaii? ?aai?iaoe?? oa ?ioa?eoiiio a?aeae?eaii? EI OIAe
i.Aei?i?iiao?ianueea. Ae?aaiic ?I anoaiiaethaaany ia i?aenoaa?
e?eoa???a, cai?iiiiiaaieo aenia?oaie AIIC (1989) ? aeeth/aa oeiiao
ee?i?/io ea?oeio, ci?ie AEA a aeeiai?oe?, ??aaiue iieaciee?a aeoeaiino?
ea?ae?iniaoeeo?/ieo oa?iaio?a.

A caeaaeiino? a?ae ii/aoeiai? oa?ai?? an? oai?? aoee iiae?eai? ia aea?
a?oie. 60 oai?eo (I a?oia), na?aaei?e a?e — 54,71,9 ?ie?a, iaea?aeoaaee
o?aaeeoe?eio oa?ai?th (?iooc?y i?o?iae?oea?eio, -aeieaoi?e,
aeacaa?aaaioe, i?o?aoe i?ieiiaiaaii? ae??), a 22 — II a?oia, na?aaei?e
a?e — 55,21,3 ?ie?a, ia i?ioyc? ia?oi? aeiae ia?aaoaaiiy a noaoe?iia??
iaeii?aciai io?eiaee ia?ooi?ai (oa?iaoeaaoe/ia o??ia “Ia?ooi?ai”,
?in?y).

Iaoiaeeea i?iaaaeaiiy ?iooc?? ia?ooi?aio. I?aia?ao aaiaeeee iaeii?aciai,
a caaaeuei?e aeic? 4-5 ie/ea iane o?ea, aioo??oiueiaaiii e?aiaeueii.
I?ney i?iaaaeaiiy a?ieia?/ii? i?iae ii/eiaee aaaaeaiiy c 5 e?aiaeue ca
oaeeeio (1oa.), i?ney /iai ?iaeee ia?a?ao 2-3 oaeeeie, i?iaeiaaeoaaee
?iooc?th ?c oaeaee?noth 10 e?ai/oa (1 oa.), ciiao ?iaeee ia?a?ao 2-3
oaeeeie. I?e a?aenooiino? ?aaeoe?? ia?aoiaeeee ia aaaaeaiiy i?aia?aoo ?c
oaeaee?noth 30-35 e?aiaeue ca oaeeeio. Na?aaeiy caaaeueia aeica
i?aia?aoo noaiiaeea 400 ie. Na?aaeiy o?eaae?noue ?iooc?? 8 aiaeei.

A iiaeaeueoiio oa?ai?y a iaio a?oiao oai?eo aoea iaeiaeiaith.

Oyaee?noue noaio oai?eo a a?oiao i?e iaaeoiaeaeaii? o a?aeiia?aeiino? c
eeaneo?eaoe??th T. Killip, J. Kimball (1967) ia ?ic??ciyeany: a ia?o?e
a?oi? o 34 (56,7%) oai?eo noai aoa ?icoe?iaiee ye I eean oyaeeino? ca
E?ee?iii ? o 26 (43,3%) ye E?ee?i II, a ae?oa?e — a?aeiia?aeii 12
(54,5%) ? 10 (45,5%). O an?o oai?eo a iiaeaeueoiio ?icaeioany Q-?I,
eieae?caoe?y yeiai i?ae a?oiaie nooo?ai ia a?ae??ciyeanue.

I?ae /an ia?aaoaaiiy a noaoe?iia?? a ia?o?e a?oi? oai?eo aia?ee 6 in?a —
1 a?ae ?ic?eao i?iea?aea, 2 — i?e iciaeao ea?ae?iaaiiiai oieo, 3 —
iaa?yeo eaaaiue. A a?oi? oai?eo, ye? iaea?aeaee ia?ooi?ai, iiia?ee 2
oai?eo — iaeei a ia?oo aeiao i?e iciaeao i?ia?anoth/iai iaa?yeo eaaaiue,
iaeei — ia 4 aeiao ia?aaoaaiiy a noaoe?iia?? a?ae ?ic?eao i?iea?aea.

Niinoa?aaeaiiy o?eaaei ??e, i?ney /iai aoei ianoaaeaii 45 oai?eo ? a?oie
? 18 — ??. A?oio eiio?ieth neeaee 40 i?aeoe/ii caei?iaeo /ieia?e?a,
aiaeia?/ieo ca a?eii.

Iaoiaee aeine?aeaeaiiy. ?aoaeueii aea/aany ee?i?/iee ia?aa?a ?I c
aiae?cii aeaieo i?i ae?aaeai?noue ? ?ioaineai?noue aieueiaiai neiae?iio,
iciaee iaaeinoaoiino? e?iaiia?ao (IE). I?iaiaeeeinue aeine?aeaeaiiy
aeoeaiino? ea?ae?iniaoeeo?/ieo oa?iaio?a — e?aaoeie?iace (EE),
ania?oaoai?iio?ainoa?ace (ANO) ia 1-5 aeiao caoai?thaaiiy. C iaoith
aea/aiiy eeniaai-o?ainii?oii? ooieoe?? e?ia? aecia/aee ?I2, ?NI2, ?I,
AA, SatO2 o aaiici?e ? a?oa??aeuei?e e?ia? ia aia?ao? AVL-620
(“Radiometr”, Aeai?y) i?e iaaeoiaeaeaii?, iai?ee?ioe? 1 aeiae, 3, 5, 7,
10 aeiao.

Aeeiai?ea iieaciee?a neiiaoi-aae?aiaeiai? nenoaie (NAN) aea/aeany ca
??aiai aeae?eaiiy c na/ath a?iaaiieo ai?i?a, ?o iiia?aaeiee?a ?
iaoaaie?o?a: aae?aiae?io (A), ii?aae?aiae?io (IA), aeioai?io —
oethi?iiao?e/iei iaoiaeii Iaoe?ii? A.O., Eenaeueiai? C.I.;
aai?e?e-ieaaeaeaai? eeneioe (AIE) — ca iaoiaeii Iaiueoeeiaa A.A. ?
Aieueoaeiai? O.Ae. (1973) c aeei?enoaiiyi iecueeiaieueoiiai
aeaeo?ioi?aco ia iaia??. ??aaiue aeiaiai? aene?aoe?? a?noeae?io,
a?noai?io (A), na?ioii?io (N) aecia/aee iaoiaeii Aa?aneiiai? Oe. ?.
(1977) ii ?aaeoe?? c i?oiooae??aei aeueaeaa?aeii; 5-iene?iaeieioeaoiai?
eeneioe — niaeo?ioioiiao?e/iei iaoiaeii. Aeine?aeaeaiiy i?iaiaeeee ia 1,
3, 5, 7, 14 aeiao caoai?thaaiiy.

Caien AEA i?iaiaeeee uiaeiy ia i?ioyc? ia?oeo 7 aei?a, a ianooiiiio —
?ac ia oeaeaeaiue. Aeey aecia/aiiy i?iaiiciaaii? iane iae?ico (III)
aeei?enoaee noaiaea?oiee AEA-iaoiae Aldrich H. R. (1988). Aeey
aecia/aiiy e?ioeaai? iane iae?ico (EII) i?iea?aea aiae?coaaeeny AEA,
caienai? ia 10-e aeaiue caoai?thaaiiy: a 10 a?aeaaaeaiiyo AEA (I, II,
III, aVF, V1-6) ioe?ithaaeeny 54 e?eoa??? ca ?o ni?iiiaei?noth
a?aeaeaaoe ?ici?? ?I (Selvester R. H., 1985). I?iaiaeeee aeiaiaa
iii?oi?oaaiiy (AeI) AEA ca aeiiiiiaith eiiieaeno “Eaioa-IO-I” c
aeei?enoaiiyi aeaio a?iiey?ieo a?aeaaaeaiue, aea aiae?coaaee ?oai?/i?
ci?ie AEA (ca aeeiai?eith naaiaioo ST ? coaoey O), a oaeiae ?eoi
na?oeaai? ae?yeueiino?.

An?i oai?ei ia?aae aeieneith aoei i?iaaaeaii aoiea?ae?ia?ao?/ia (Aoi-EA)
ianoaaeaiiy ia naeoi?aeueiiio aeaioi??iiio aoiea?ae?ia?ao? “Ultramark-9”
(ATL, NOA) a I-, A-, aeiiea?-, eieuei?iaee aeiiea? ?aaeeiao ca
caaaeueiii?eeiyoeie iaoiaeeeaie. I?e oeueiio aea/aee naaiaioa?i?
ii?ooaiiy nei?ioiino?, oa iieacieee, ui oa?aeoa?ecothoue nei?ioio
ni?iiiaei?noue i?iea?aea (e?ioeaaee ae?anoie?/iee ia’?i — EAeI,
e?ioeaaee nenoie?/iee ia’?i — ENI, oaea?iee ia’?i — OI, o?aeoe?th
aeeeaeo — OA, nooi?iue ia?aaeiuei-caaeiueiai oei?i/aiiy — DeltaS).
Ii?ooaiiy nenoie?/ii? ooieoe?? anoaiiaethaaee ca aaee/eiith OA (i?e
OA45%), a ae?anoie?/ii? — ca oa?aeoa?ii o?aini?o?aeueiiai e?iaioieo.

I?e ?ao?iniaeoeaiiio ianoaaeaii? aecia/aee iayai?noue noaiiea?ae??
iai?oaeaiiy oa ?? ooieoe?iiaeueiee eean (OE), ae?aaeai?noue IE, noai
i?iea?aea e?aiai oeoii/ea (EO) ca aeaieie Aoi-EA, /anoioo iiaoi?ieo ?I
? aini?oae?caoe?e ca ieioeee ??e, caeaoi?noue iiaa?iooenue aei i?aoe?.

Iaea?aeai? ?acoeueoaoe aoei ia?iaeaii iaoiaeaie aa??aoe?eii? noaoenoeee,
ui ?aae?coaaeeny noaiaea?oieie iaeaoaie i?eeeaaeieo i?ia?ai
noaoenoe/iiai aiae?co STADIA 4.0 ? STATISTICA FOR WINDOWS 5.0 ia
ia?niiaeueiiio eiii’thoa?? IBM Pentium-166 MMX i?ae oi?aae?iiyi
iia?aoe?eii? nenoaie MS DOS 7.10 a na?aaeiaeu? Windows 95 OSR 2.
I?iaaaeaii aaaaoii??iee ei?aeyoe?eiee ? ?aa?aneaiee aiae?ce c
aecia/aiiyi e?eoa??th iaeii??aeiino? aeey ia?ieo aei???a.

?ACOEUeOAOE AeINE?AeAEAIIss OA ?O IAAIAI?AIIss

I?e i?iaaaeaii? ee?i?/iiai niinoa?aaeaiiy a ia?oo aeiao ?I a?eue
a?aecia/aany o a?eueoino? oai?eo iaio a?oi: o 93,4% — ? a?oie ? o?eueee
o 73,7% — ?? (?<0,05). Oey ??cieoey caa??aaeanue ? aei o?aouei? aeiae, eiee aaaaeaiiy ciaaiethth/eo cania?a aeey eoi??oaaiiy aieueiaiai i?enooio iio?aaoaaee 65,7% ? 36,4% iaoe??io?a a?aeiia?aeii (?<0,05). A iiaeaeueoiio /enei oai?eo, o yeeo a?eue a?aeiiaethaaany, ciaiooaaeinue a iaio a?oiao. Iiaiioe?iia eoi??oaaiiy aieth o oeo, ui iaea?aeaee ia?ooi?ai, /ano?oa aeinyaaeinue aaaaeaiiyi aiaeaaoee?a (?<0,05) ia i?ioyc? anueiai ia??iaeo niinoa?aaeaiiy. Aaaaeaiiy ia?eioee?a, ii?aeiaiiai aaaaeaiiy aiaeaaoee?a ? ia?eioee?a oa iiaoi?iiai aaaaeaiiy i?aia?ao?a oe? oai?? iio?aaoaaee ??aeoa. Nooo?aa cia/aiiy a ?icaeoeo iaiai?ioieo ci?i a i?iea?ae?, ia aeoieo a?eueoino? aeine?aeiee?a (Nu?eei A. E., 1991; ?yaia A. A., 1996; Aaoeo?a A. A., 1993), iaeaaeeoue a?iien??. Aiae?c iieaciee?a iai?oaeaiiy aac?a e?ia? oa eeneioii-iniiaiiai noaio i?e iaaeoiaeaeaii? o oai?eo iaio a?oi aeyaea ae?aaeaiee eeniaaee ai?a (?aI2 cieaeoaaeinue ia 10,8%, a ?vI2 c?inoaei ia 50,2%) c i?iyaaie iaoaaie?/iiai aoeeaeico. I?ney aaaaeaiiy ia?ooi?aio a?aeaoaaeanue oei/aniaa ii?iae?caoe?y iieaciee?a aac?a e?ia? i?e ciaioaii? i?iya?a iaoaaie?/iiai aoeeaeico a ia?oo aeiao i?ney ?iooc??, a a iiaeaeueoiio niinoa??aaeinue a?eueo ?aii? ? no?eea ?o a?aeiiaeaiiy o ii??aiyii? c oai?eie ? a?oie. I?e iaaeoiaeaeaii? ia AEA o an?o oai?eo a?aecia/aeenue iciaee iaeaino??oi? noaae?? ?I: aeaaaoe?y naaiaioo ST ia 2 ii ? a?eueoa a aeaio ? a?eueoa ii?yae?icoaoiaaieo a?oaeieo a?aeaaaeaiiyo i?e ia?aaei?e eieae?caoe?? aai a aeaio noaiaea?oieo ieaei?o a?aeaaaeaiiyo c ?aoeei?ieiei cieaeaiiyi ST o ia?aaei?o aai aieiaeo a?aeaaaeaiiyo i?e ieaei?e eieae?caoe??. Ia e?iaoeue ia?oi? aeiae o 10 (16,7%) oai?eo I a?oie ? o 12 (54,5%) oai?eo II a?oie niinoa??aaeiny cieaeaiiy naaiaioo ST ia 2-3 ii, ui na?ae/eei i?i ciaioaiiy ?ioaineaiino? i?ioean?a iioeiaeaeaiiy a noaai?ea?ae?aeueieo oa?ao i?iea?aea. Aeaeo?iea?ae?ia?ao?/i? iciaee oi?ioaaiiy i?aeaino?i? noaae?? ?I o 17 (77,3%) oai?eo ?? a?oie c'yaeeeny ia 2 aeiao caoai?thaaiiy, a o ? a?oi? - ia 4. A iiaeaeueoiio oa?i?ie iiyae iciae noaae?? ?oaoethaaiiy ia AEA a iaio a?oiao i?aeoe/ii ia a?ae??ciyeeny ? c’yaeeenue ia 10-14 aeiao. III aoea ?ic?aoiaaia ca aeaieie AEA, ciyoeie a iiiaio aieueiaiai i?enooio. ?? aaee/eia a a?oiao i?aeoe/ii ia ?ic??ciyeanue: a I - 24,01,9% ? a II -27,72,5% iane i?iea?aea EO. ?ic?aoiaaia EII neeaea a?aeiia?aeii 212% oa 17,41,7%. Oaeei /eiii, ia’?i iane caa?aaeaiiai i?iea?aea aeey oai?eo I a?oie neeaa 12,51,1%, a aeey II – 27,02,5% (p<0,01), ui aea? i?aenoaao i?eioneaoe iiceoeaio ae?th ia?ooi?aio ia aeeiai?eo ?ici???a ciie iae?ico (?en. 1). ?en. 1. Aaee/eie i?iaiiciaaii? oa e?ioeaai? iane iae?ico o oai?eo ia ?I i?e ??cieo aa??aioao ii/aoeiai? oa?ai?? Iaoai?ciii oeueiai nei??oa anueiai noaei iie?auaiiy i?e?ioee?eoeyoe?? oa iineeaiiy aeeooc?? I2, ui caaacia/o? aaeain i?ae eiai niiaeeaaiiyi ? aeinoaaeith, ? ye iane?aeie a?aeaoaa?oueny ciaioaiiy i?iya?a ?oai?? a ia?e?ioa?eoi?e cii? ? caa?aaeaiiy a?eueoiai /enea ea?ae?ii?ioeeo?a, caeaoieo aei aoaeoeaiiai nei?i/aiiy. A?aeiii, ui naia ia iaae? ciie ?ioa?eoo ? iai?ioii iioeiaeaeai? ee?oeie, ca ?aooiie yeeo iiaeeeaa a?eueo iiaiioe?iia o ooieoe?iiaeueiiio a?aeiioaii? a?aeiiaeaiiy ae?eyiie i?iea?aea (Eeoaeoeeee I. O. e niaao., 1994). I?e i?iaaaeaii? AeI AEA o?aiceoi?ia ?oai?y i?iea?aea aoea aeyaeaia o 10 oai?eo ia?oi? a?oie ? o 3 iaoe??io?a ae?oai? (?>0,05). O 4 oai?eo ia?oi?
a?oie aeyaeai? ai?ciaee o?eueee aieueiai? ?oai??, o 4 niinoa??aaeiny
ii?aeiaiiy aieueiaeo ? aacaieueiaeo ai?ciae?a, o?eueee aacaieueiaa
?oai?y i?iea?aea ca?a?no?iaaia o 2. A a?oi? oai?eo, yeei ai?iaeiaae
ia?oi? aeiae aoea i?iaaaeaia ?iooc?y ia?ooi?aio, aoee ca?a?no?iaai?
ai?ciaee o?eueee o?aiceoi?ii? aacaieueiai? ?oai?? i?iea?aea. A??ia?aeii?
??cieoe? a iioe?aiino? ai?ciae?a ieio/i? ?oai?? i?iea?aea i?ae a?oiaie
ia a?aecia/aii, i?ioa iiaeia aiai?eoe i?i iaio ae?aaeaiee aieueiaee
neiae?ii a a?oi? oai?eo, ui iaea?aeaee ia?ooi?ai (oaae.1). Noia?ia
aeiaiaa o?eaae?noue ?oai?? i?iea?aea a ia?o?e a?oi? aeyaeeanue iaeaea
ao?e/? a?eueoith, i?ae a ae?oa?e (?<0,05). O?eaae?noue aacaieueiai? ?oai?? i?iea?aea oa ?? /anoioa a ia?o?e a?oi? oai?eo oaae aoea a?eueoith. Oaaeeoey 1 Iieacieee aeiaiaiai iii?oi?oaaiiy AEA o oai?eo ia A?I i?e ??cieo aa??aioao ii/aoeiai? oa?ai?? I i e a c i e eA?oia ? (n=22)A?oia ?? (n=10)Noia?ia aeiaiaa o?eaae?noue, oa.: ?oai?? i?iea?aea aieueiai? ?oai?? i?iea?aea aacaieueiai? ?oai?? i?iea?aea 82,46,7* 35,82,9 46,63,8* 27,23,5* - 27,23,5*Aeiaiaa e?euee?noue ai?ciae?a: ?oai?? i?iea?aea Aieueiai? ?oai?? i?iea?aea Aacaieueiai? ?oai?? i?iea?aea 3,00,2 2,50,2 3,70,3 2,30,3 - 2,30,3I?ei?oea: * -?<0,05 I?e aiae?c? ?eoio na?oeaai? ae?yeueiino? c’ynoaaeinue, ui a ae?oa?e a?oi? oai?eo caaaeueia e?euee?noue oeoii/eiaeo aeno?anenoie (OA) aoea a 4 ?ace iaioith (?<0,002). Aiaeia?/ia ea?oeia niinoa??aaeanue ? i?e aiae?c? iaeneiaeueiiai /enea OA/aiae: a ?? a?oi? ?o e?euee?noue aoea a 3,4 ?ace iaioith ? neeaea 17,38,9, oiae? ye a ia?o?e a?oi? - 58,617,3 (?<0,05). A?oiiaa oeoii/eiaa aeno?anenoie?y ? aeno?anenoie?y aenieeo a?aaeaoe?e (oeio R/T) a a?oi? oai?eo, ui io?eiaee ia?ooi?ai, cono??/aeanue a??ia?aeii ??aeoa (?=0,07 ? ?=0,04) (?en.2). ?en. 2. *anoioa ie?aieo aeae?a a?eoi?e o oai?eo ia A?I i?e ??cieo aa??aioao ii/aoeiai? oa?ai?? Ioaea, aiae?c aeaieo AeI i?aeoaa?aeaeo? ni?eyoeeaee aieea ?iooc?? ia?ooi?aio ia noai ei?iia?iiai e?iaiia?ao ? iai?iieo i?ioean?a a i?iea?ae?, ui ciaeoei a?aeia?aaeaiiy a ciaioaii? i?iya?a ?oai?? ? oi?ioaaii? ina?aaee?a aeoii?/iiai ?eoio. Aea/aiiy noaio NAN iieacaei, ui a ?? a?oi? oai?eo ni?aa?aeiioaiiy i?ae eaieaie NAN aoee aeecueeeie aei o?c?ieia?/ieo, ui ia iiaei ia aieeiooe ni?eyoeeai ia iiaeaeueoee ia?aa?a caoai?thaaiiy. A ? a?oi? oai?eo a?aecia/aeiny i?eai?/aiiy no?an-e?i?ooth/i? eaiee NAN, ui noi?iaiaeaeoaaeinue aeniaaeaiiyi ?? ?aca?aieo iiaeeeainoae, a i?ioeane iaoaaie?cio ia?aaaaeaee iaae i?ioeanaie neioaco, ui i?aeoaa?aeaeoaaeinue cieaeaiiyi aene?aoi?ii? AIE a 1-5 aeiao a?aeiia?aeii ia 60,2% - 78,5% a?ae ii?ie. Eiao?oe??io ni?aa?aeiioaiiy A/IA, ui a?aeia?aaea? ei?aeyoe?th i?ae iaae?aoi?iith ? ai?iiiaeueiith eaieaie nae?aoe?? eaoaoieai?i?a, a oe?e a?oi? oai?eo ia an?o aoaiao niinoa?aaeaiiy aoa aeuei, i?ae eiai aiaeia?/i? cia/aiiy a a?oi? oai?eo, ye? io?eiaee ia?ooi?ai. Oea na?ae/eei i?i ia?aaaaeaiiy aeoeaaoe?? ai?iiiaeueii? eaiee NAN. Naia oeei a iaai?e i??? iiaeia iiynieoe ? iayai?noue no?eeiai aieueiaiai neiae?iio o oai?eo ia?oi? a?oie. Ia aeoieo aeayeeo aaoi??a, i?aeaeuaiiy ??aiy A a ii?aeiaii? c iaaeinoaoi?i ca?eueoaiiyi ??aiy IA nei??oa anueiai iaaaoeaii aieeaa? ia i?iea?ae, ai i?e oeueiio a?aeaoaa?oueny ca?eueoaiiy eiai iio?aae a eeni?, c?inoa? oeaieiia a?iien?y (Eeiiaaoeeee A.I. e niaao., 1996; Choy A. at al., 1994). Ia?aoo?, oea iiaea ni?e/eieoe ?icoe?aiiy ciie iae?ico o oaeeo oai?eo. I?iaaaeaiee aiae?c aeyaea, ui a ? a?oi? oai?eo iaea?eueo o?niee i?yiee ei?aeyoe?eiee ca'ycie ?ici???a ciie iae?ico a?aecia/a?oueny i?ioyaii ia?oeo i'yoe ae?a c ??aiai A (r=0,88; 0,83; 0,84 i?e ?<0,05), ui ocaiaeaeo?oueny c aeaieie ?ioeo aeine?aeiee?a ? i?aeoaa?aeaeo? i?eiouaiiy i?i iaaaoeaiee aieea ia?aaaaeii ai?iiiaeueii? eaiee NAN ia ?icaeoie ?I (Iaiei E. A., 1988; Sigurdson A., 1994). Oeae ca'ycie iineaaeth?oueny i?ney 7 aeiae, ui iiaea na?ae/eoe i?i cae?i/aiiy oi?ioaaiiy ina?aaeeo iae?ico o oe??? a?oie oai?eo. Aaaaeaiiy ia?ooi?aio a iaai?e i??? ci?ithaaei oa?aeoa? noaio NAN ? ?? aieea ia oi?ioaaiiy ciie iae?ico. A?eueo aeecuee? aei o?c?ieia?/ieo cia/aiiy iieaciee?a NAN, ia?aaaaeia aeoeaaoe?y ?? iaae?aoi?ii? eaiee i?ecaaee aei cieaeaiiy iaaaoeaiiai aieeao A. Aiae?c aeaieo i?i ci?ie a?noai?i?aaeoeaii? oa na?ioii?ia?a?/ii? nenoai iieacaa, ui a ia?oo aeiao caoai?thaaiiy ??aaiue A aoa i?aeaeuaiei a iaio a?oiao oai?eo, ui na?ae/eei i?i a?iien?th i?aai?a ? oeaiei, i?e/iio a ia?o?e a?oi? a?i ia?aaeuoaaa ii?iaeuei? cia/aiiy a 4,6 ?ace, a a ae?oa?e - o?eueee a 1,7. A iiaeaeueoiio a iaio a?oiao oai?eo a?aecia/aeinue cieaeaiiy ??aiy A, yea noi?iaiaeaeoaaeinue c?inoaiiyi ??aiy aene?aoi?iiai N. Oea iiaea na?ae/eoe i?i aeoeaaoe?th no?an-e?i?ooth/eo nenoai a iaio a?oiao ianoaaeaieo. I?ioa, a a?oi? oai?eo, ye? iaea?aeaee ia?ooi?ai, ii?iae?caoe?y ??aiy A a?aeaoaaeany oaeaeoa ? a a?eueo?e i???. I?e ni?anoaaeaii? iaea?aeaieo ?acoeueoao?a c aeaieie i?i ee?i?/iee ia?aa?a caoai?thaaiiy c’yniaaii, ui i?aeaeuaiee ??aaiue A aoa, ye i?aaeei, o oai?eo ?c no?eeei aieueiaei neiae?iiii. Aiaeia?/i? ?acoeueoaoe aoee iaea?aeai? oaeiae a ?iaioao aaoi??a, ui aea/aee ??aaiue A ? N a ieaci? o oai?eo ia ?I (Ieeieaaaa A. A. e niaao., 1997). Ei?aeyoe?eiee aiae?c, i?iaaaeaiee a a?oiao, a oaeiae ni?anoaaeaiiy c ?ici??aie e?ioeaai? ciie iae?ico, aeyaea o?niee i?yiee ca'ycie i?ae ?ici??aie ciie iae?ico ? ??aiai N i?aeoe/ii ia an?o aoaiao niinoa?aaeaiiy aeey ? a?oie oai?eo, iaea?eueo cia/ouei a?i aoa ia 1-3 aeiao caoai?thaaiiy (r=0,51; 0,5; ?<0,05). I?e ee?i?/iiio ianoaaeaii? oai?eo ia?aae aeieneith ?c noaoe?iia?o ae?aaeai?noue IE o oai?eo ?? a?oie aeyaeeanue iaioith, i?ae a ? a?oi?: IIA no. IE o ieo anoaiiaeaii a 3 (15%) aeiaaeeao, a a ia?o?e - a 20 (35,7%). I?e Aoi-EA aeine?aeaeaii? a iaio a?oiao oai?eo a iaeano? ia?aianaiiai ?I aecia/aeenue ae?eyiee aneia?a??, aea e?euee?noue aiaa?eci a a?oi?, ui iaea?aeaea ia?ooi?ai, aeyaeeanue a??ia?aeii iaioith (1 ? 8 a?aeiia?aeii). O ieo a?eueo oaeaeei ? iiaii a?aeaoaaeinue a?aeiiaeaiiy ooieoe?? i?iea?aea EO, i?i ui na?ae/eoue caa?aaeaiiy nei?ioii? caeaoiino? i?iea?aea o an?o iaoe??io?a, a??ia?aeii ??aeoa - o 2 oai?eo i?ioe 17- aeyaeaii ii?ooaiiy eiai ae?anoie?/ii? ooieoe??. Aeey ioe?iee a?aeaeaeaieo ?acoeueoao?a e?eoaaiiy ?I i?iaaaeaii ?ao?iniaeoeaia ianoaaeaiiy oai?eo iaio a?oi /a?ac ??e. Iiaoi?i? ?I aeieeee o 4 /ieia?e ?c ia?oi? ? o iaeiiai c ae?oai? a?oie. Iaea?aeai? iaie ee?i?/i? aeai? aeicaieeee aaaaeaoe, ui a ? a?oi? noaiiea?ae?y iai?oae III OE iaea i?noea o 15 (33,3%) ? II OE o 9 (20%) iaoe??io?a. Na?aae oai?eo ?? a?oie anoaiiaeaia noaiiea?ae?y o?eueee II OE - o 5 /ieia?e. Ee?i?/i? iciaee IE aeyaeai? iaie o an?o oai?eo, i?ioa a ia?o?e a?oi? IIIA no. ?acaeioeanue o 17 (37,8%), a a ae?oa?e - o 3 /ieia?e. Aei i?aoe? iiaa?ioeenue iaeaea an? oai?? ?? a?oie (16 c 18) /ieia?e, a a ? - aea? o?aoeie (30 c 45). I?iaaaeaia Aoi-EA aeine?aeaeaiiy aeyaeei ae?eyiee aneia?a?? a i?noeyo ?icaeiaiiy iino?ioa?eoiiai ea?ae?ineea?ico, aea aiaa?ecie aeieeee o 11 oai?eo ia?oi? a?oie ? o 3 - ae?oai?, oiaoi, a??ia?aeii ??aeoa (?<0,05). Ii?ooaiiy ae?anoie?/ii? ooieoe?? e?aiai oeoii/ea anoaiiaeaii o 28 ? o 2 oai?eo a?aeiia?aeii (?<0,05). Ni?anoaaeaiiy aeaieo i?i noai nei?ioii? ooieoe?? i?iea?aea ca ?acoeueoaoaie Aoi-EA aeine?aeaeaiiy, i?iaaaeaiiai ia?aae aeieneith ?c noaoe?iia?o, ?c a?aeiia?aeieie aeaieie, iaea?aeaieie /a?ac ??e i?ney aeieeiaiiy ?I, aeyaeei ?? iie?auaiiy o oai?eo, ui io?eiaee ia?ooi?ai, i?i ui na?ae/eoue ciaioaiiy ENI i?e iaeii/aniiio ca?eueoaii? OI. A oie aea /an o oai?eo ? a?oie oeae iieaciee aoa a??ia?aeii a??oei, ye o ii??aiyii? c ?? a?oiith, oae ? a ii??aiyii? c eiai aaee/eiith o ieo aea ia?aae aeieneith. Aiaeia?/ia aeeiai?ea aeyaeaia iaie ? a cia/aiiyo EAeI. *a?ac ??e o oai?eo ? a?oie oeae iieaciee ca?eueooaaany, oiae? ye a ?? a?oi? a?i cieceany (?<0,05 a iaio aeiaaeeao). Eiao?oe??io ENI/EAeI, ui oa?aeoa?eco? aoaeoeai?noue iii?iaeiaiiy EO, a ? a?oi? c??n aei 0,46 i?ioe 0,43, ui aiai?eoue i?i aeayea iia??oaiiy ooieoe?iiaeueiiai noaio i?iea?aea EO. A ?? a?oi? oai?eo oeae iieaciee i?aeoe/ii ia ci?ieany - 0,36 ? 0,37 a?aeiia?aeii. A?aeiii, ui eiiiainaoe?y ianinii? ooieoe?? e?aiai oeoii/ea a?aeaoaa?oueny ca ?aooiie aeei?enoaiiy aeaio iniiaieo aaiiaeeiai?/ieo iaoai?ci?a: O?aiea-Noa?e?iaa ? a?ia?ooieoe?? ?ioaeoiiai i?iea?aea (Acecia A.A., 1998). Io?eiai? iaie aeai? iieacaee, ui a ia?o?e a?oi? oai?eo aeii?ioth/ei a ?icaeoeo iaoai?ci?a eiiiainaoe?? noa? ?aca?a aeeeyoaoe?? (ca?eueoaiiy EAeI, ENI, ui noi?iaiaeaeo?oueny c?inoaiiyi OI). A ae?oa?e a?oi? iaea?eueo a??ia?aeii ia?aaaaeaee iaoai?cie eiiiainaoe??, iia'ycai? c a?ia?ooieoe??th ?ioaeoiiai i?iea?aeo (ca?eueoaiiy OI, i?e ciaioaii? EAeI ? ENI), ui aeey iueiai ? aia?aaoe/ii a?eueo aea?aeiei. Ana aeuaaeeeaaeaia aea? i?aenoaao c?iaeoe ianooii? aeniiaee ? i?aeoe/i? ?aeiiaiaeaoe??. AENIIAEE 1.Ee?i?/iee ia?aa?a aino?iai ?ioa?eoo i?iea?aea i?e canoinoaaii? iaaaiiaeia?iiaiai ia?aiinieea eenith - ia?ooi?aio - a eiai eiiieaeni?e oa?ai?? noi?iaiaeaeo?oueny ciaioaiiyi ae?aaeaiino? aieueiaiai neiae?iio (/anoioe oa ?ioaineaiino? aieueiaeo iaiaae?a) ? i?iya?a iaaeinoaoiino? e?iaiia?ao. 2.I?e aeei?enoaii? ia?ooi?aio a?aeaoaa?oueny a?eueo ?aii? oi?ioaaiiy aeaeo?iea?ae?ia?ao?/ieo iciae i?aeaino?i? noaae?? ?ioa?eoo, a ia’?i iane caa?aaeaiiai i?iea?aea a?eueo i?ae a 2 ?ace ia?aaeuo? oaeee a ia?o?e a?oi? (272,5% ? 12,51,1% a?aeiia?aeii, ?0,05), ui ni?ey? a?eueo iiaiiio a?aeiiaeaiith ooieoe?? i?iea?aea e?aiai oeoii/ea. 3.Ca aeaieie aeiaiaiai iii?oi?oaaiiy AEA o oai?eo, yeei aoea i?iaaaeaia ?iooc?y ia?ooi?aio, aoee ca?a?no?iaai? ai?ciaee o?eueee aacaieueiai? ?oai?? i?iea?aea, aeiaiaa o?eaae?noue ?o aoea ei?iooith ? noi?iaiaeaeoaaeanue iaioei /eneii ii?ooaiue ?eoio, ui na?ae/eoue i?i ciaioaiiy i?iya?a ?oai?? ? oi?ioaaiiy ina?aaee?a aeoii?/iiai ?eoio. 4. A?aeiiaeaiiy aei o?c?ieia?/iiai ??aiy iieaciee?a neiiaoi-aae?aiaeiai? nenoaie a ia?oo aeiao i?ney aeei?enoaiiy ia?ooi?aio oa a?eueo ni?eyoeeaa ni?aa?aeiioaiiy i?ae ?? eaieaie a ianooiiiio, ui noi?iaiaeaeoaaeinue oaeaeoith ii?iae?caoe??th noaio a?noai?i?aaeoeaii? ? na?ioii?ia?a?/ii? nenoai, iiaea aooe ?icoe?iaia ye oaeoi?, ui ciaioo? oeaieiio a?iien?th /ei iiia?aaeaeo? ?icoe?aiiy ciie iae?ico. 5.Aeine?aeaeaiiy ooieoe?iiaeueiiai noaio e?aiai oeoii/ea aeyaeei ciaioaiiy ii?ooaiue eiai nenoie?/ii? oa ae?anoie?/ii? ooieoe?e, ui na?ae/eoue i?i a?eueo iiaia caa?aaeaiiy i?iea?aea, o aeiaaeeao, eiee a eiiieaen? ?ioaineaii? oa?ai?? aino?iai ia??iaeo ?ioa?eoo i?iea?aea aoei canoiniaaii ia?ooi?ai. 6.?acoeueoaoe ?ao?iniaeoeaiiai niinoa?aaeaiiy iieacaee, ui i?ney i?iaaaeaiiy ?iooc?? ia?ooi?aio a?aecia/a?oueny a?eueo ni?eyoeeaee ia?aa?a iino?ioa?eoiiai ia??iaeo, ui ae?aaea?oueny a iaio?e e?eueeino? iiaoi?ieo ?ioa?eo?a ? iaio?e oyaeeino? iaaeinoaoiino? e?iaiia?ao. I?AEOE*I? ?AEIIAIAeAOe?? 1.Canoinoaaiiy iaaaiiaeia?iiaiai ia?aiinieea eenith - ia?ooi?aio - aaaea aei ciaioaiiy yaeu a?iienai?? ? oeaieiii? a?iien??, ui e?i?oo? a?iiene/ia iioeiaeaeaiiy na?oeaaiai i'yca, ni?ey? iaiaaeaiith ciie iae?ico ? iiaea aooe ?aeiiaiaeiaaiei a eiiieaen? ?ioaineaii? oa?ai?? aino?iai ia??iaeo ?ioa?eoo i?iea?aea. 2.Ia?ooi?ai iiaea aooe i?ecia/aiee oai?ei ia aino?ee ?ioa?eo i?iea?aea, ye? iaae?eoee a noaoe?iia? a ia?o? 6 aiaeei a?ae ii/aoeo aieueiaiai iaiaaeo. I?aia?ao aaiaeyoue iaeii?aciai a caaaeuei?e aeic?5 ie/ea aaae, aioo??oiueiaaiii e?aiaeueii, c? oaeaee?noth 30-35 e?aiaeue ca oaeeeio. 3.Aeei?enoaiiy iaeii?aciai? ?iooc?? ia?ooi?aio a eiiieaeni?e oa?ai?? ?I noi?iaiaeaeo?oueny a?eueo ni?eyoeeaei ee?i?/iei ia?aa?aii caoai?thaaiiy: ciaioaiiyi ae?aaeaiino? aieueiaiai neiae?iio a aino?iio ia??iae? ? ae?aaeaiino? iaaeinoaoiino? e?iaiia?ao ia an?o aoaiao niinoa?aaeaiiy. 4.Aea/aiiy noaio neiiaoi-aae?aiaeiai?, a?noai?i?aaeoeaii? oa na?ioii?ia?a?/ii? nenoai aeicaiey? ioe?ieoe aoaeo oa?ai?? o oai?eo, yeei i?iaiaeeeanue ?iooc?y ia?ooi?aio. 5.Aecia/aiiy aaee/eie i?iaiiciaaii? ? e?ioeaai? iane iae?ico c ?ic?aooieii iane caa?aaeaiiai i?iea?aea, i?iaaaeai? ca aeaieie AEA, iiaeooue aeei?enoiaoaaoenue aeey ioe?iee aoaeoeaiino? e?eoaaiiy ?I. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Onaiei E.A., Ano??i A.I., Ia?oeaaa O.I., *a?eaniaa I.A. Aaiii?ioaeoi?i? aoaeoe ia?ooi?aio o oai?eo ia aino?ee ?ioa?eo i?iea?aea // Iaaee/i? ia?niaeoeae.-1996.-?1.-N.21-27. 2. Ia?oeaaa O.I., *a?eaniaa I.A. Ioe?iea ooieoe?? i?iea?aea o a?aeaeaeaiiio ia??iae? i?ney ia?aianaiiai ?ioa?eoo i?iea?aea i?e ??cieo aa??aioao ii/aoeiai? oa?ai?? // Iaaee/i? ia?niaeoeae.-1998.-O.???, ?3.- N.21-23 3. *a?eaniaa I.A. Aeine?aeaeaiiy i?ioe?oai?/iiai aieeao ia?ooi?aio o oai?eo ia aino?ee ?ioa?eo i?iea?aea ca ?acoeueoaoaie oieoa??anueeiai iii?oi?oaaiiy // Iaaee/i? ia?niaeoeae.-1998.-O.???, ?4.- N. 20-22. 4. Ia?oeaaa O.A., *a?eaniaa I.A. Iniaaiiinoe aeeiaieee aieaaiai neiae?iia a ino?ii ia?eiaea eioa?eoa ieiea?aea a caaeneiinoe io ia/aeueiie oa?aiee // Iaoa??aee XV c‘?caeo oa?aiaao?a Oe?a?ie.-E., 1998.-N.218-219. 5. *a?eaniaa I.A. Aeeiaieea iieacaoaeae aaciaiai ninoaaa e?iae o aieueiuo ino?ui eioa?eoii ieiea?aea iiae aeeyieai ia?ooi?aia // Iaoa??aee 2 Iaoe?iiaeueiiai eiia?ano aianoac?ieia?a Oe?a?ie.- E.:Aeua oeiea.- 1996.- N.213. 6. Onaiei E.A., Ia?oeaaa O.A., *a?eaniaa I.A., Eeaoeoe Y.I. Oa/aiea ino?iai ia?eiaea eioa?eoa ieiea?aea o aieueiuo, iieo/aaoeo ia?ooi?ai // Iaoa??aee 2 Iaoe?iiaeueiiai eiia?ano aianoac?ieia?a Oe?a?ie.- E.:Aeua oeiea, 1996.- N.210-211. 7. Onaiei E.A., Ia?oeaaa O.I., *a?eaniaa I.A. Aieea ?iooc?? ia?ooi?aio ia ?ici??e ina?aaeeo iae?ico o oai?eo ia aino?ee ?ioa?eo i?ieaaea // Oace aeii. VI eiia?ano na?oiai? oaaea?aoe?? oe?a?inueeeo e?ea?nueeeo oiaa?enoa.-Iaeana.-1996, N.152. 8. Onaiei E.A., Yno?ei A.A., Ia?oeaaa O.A., *a?eaniaa I.A. I?ioeaieoaie/aneea yooaeou ia?ooi?aia o aieueiuo n ino?ui eioa?eoii ieiea?aea // Ia?ooi?i?aaie/aneea niaaeeiaiey a aeieiaee e iaaeeoeeia: Na. iao/i. o?. /Ioueineee iao/. oeaio? ?inneeneie AI.- Ioueii, 1997.-Aui.VII. N.174-187. 9. Onaiei E.A., Ia?oeaaa O.A., *a?eaniaa I.A. Iiuo i?eiaiaiey ia?ooi?aia aeey ea/aiey aieueiuo ino?ui eioa?eoii ieiea?aea // Oac. aeiee. IV ?inneeneiai iaoeeiiaeueiiai eiia?anna “*aeiaae e eaea?noai”.- I.,1997.- N.132. 10. *a?eaniaa I.A. Ioaeaeaiiua ?acoeueoaou eeeie/aneiai ianeaaeiaaiey aieueiuo eioa?eoii ieiea?aea, a oa?aieth eioi?uo aue aeeth/ai ia?ooi?ai // Oac. aeiee. V ?inneeneiai iaoeeiiaeueiiai eiia?anna “*aeiaae e eaea?noai”.-I.,1998.- N.535. 11. *a?eaniaa I.A. I aiciiaeiinoe i?eiaiaiey iaaaiiaeiaeiiaiai ia?aiin/eea eenei?iaea- ia?ooi?aia a ino?ii ia?eiaea eioa?eoa ieiea?aea // Aeooaeuei? ieoaiiy aenia?eiaioaeueiiai aeei?enoaiiy aa?ioa?ai??: ? Oe?a?inueea iaoeiai-i?aeoe/ia eiioa?aioe?y c i?aeia?iaeiith o/anoth: Oace aeii.- Aei?i?iiao?ianuee, 1995.- N.101. 12. *a?eaniaa I.A., Iaaeaiei A.I., Aeiia?aaeiaa E.I., Iaoaoiiiaa I.I. E aeeiaieea naaiaioa ST o aieueiuo ino?ui eioa?eoii ieiea?aea // Aeooaeueiua aii?inu iaaeeoeeiu e aeieiaee: Na. no. / AeAIA.- Aeiai?iiao?iane, 1996.- Aui.7, /.?.- N.101. 13. *a?eaniaa I.A. Ooieoeeiiaeueiay aeoeaiinoue neiiaoi-aae?aiaeiaie nenoaiu o aieueiuo ino?ui eioa?eoii ieiea?aea // Aeooaeueiua aii?inu iaaeeoeeiu e aeieiaee: Na. no. /AeAIA. - Aeiai?iiao?iane, 1997.- Aui. 9.- N.126. 14. *a?eaniaa I.A., Caiieueneee N.A., Oa?anaiei A.A., Oei/aiei A.I., Oeeeiiaiei I.A. Iniaaiiinoe aeeiaieee e?aaoeieeiacu a caaeneiinoe io i?iaiaeeiie oa?aiee // Aeooaeueiua aii?inu iaaeeoeeiu e aeieiaee: Na.no. / AeAIA.- Aeiai?iiao?iane, 1997.- Auione 9.- N.125. AIIOAOe?ss *a?eaniaa I. A. Iniaeeaino? ia?aa?ao ?ioa?eoo i?iea?aea i?e aeei?enoaii? ia?ooi?aio. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeueiinoth 14.01.11 - ea?ae?ieia?y. - Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Oa?e?a, 1999. Aeena?oaoe?th i?enay/aii iaa?oiooaaiith iiaeeeaino? ? aeioe?eueiino? canoinoaaiiy a eiiieaeni?e oa?ai?? aino?iai ia??iaeo ?ioa?eoo i?iea?aea (?I) iaaaiiaeia?iiaiai ia?aiinieea eenith - ia?ooi?aio (oa?iaoeaaoe/ia o??ia “Ia?ooi?ai”, ?in?y). C oe??th iaoith ianoaaeaii 82 oai?eo ?I, 22 c yeeo a 1 aeiao i?iaaaeaia ?iooc?y i?aia?aoo. Aea/aii eiai aieea ia ee?i?/iee ia?aa?a aino?iai ?I, aaciaee neeaae e?ia? ? eeneioii-iniiaiee noai, aeeiai?eo aeaeo?io?c?ieia?/ieo iieaciee?a, ?aaeoe?th neiiaoi-aae?aiaeiai?, a?noai?i?aaeoeaii? ? na?ioii?ia?a?/ii? nenoai, iino?ioa?eoia ?aiiaeaethaaiiy i?iea?aea. Aeiaaaeaii, ui ia?ooi?ai ciaioo? a?iienai?th ? oeaieiio a?iien?th. Anoaiiaeaii, ui aaaeo/ei ? aieea i?aia?aoo ia aaee/eio e?ioeaai? ciie iae?ico i?iea?aea. Ciaioaiiy ?ici???a ooeiaeaeaiiai i?iea?aea iaoiiaeei a?eueo iiaia a?aeiiaeaiiy eiai ooieoe??, ui i?aeoaa?aeaeo?oueny iaioith oyaee?noth na?oeaai? iaaeinoaoiino? o oeeo iaoe??io?a ia an?o aoaiao niinoa?aaeaiiy. Cai?iiiiiaai? ?aeiiaiaeaoe?? uiaei eiai canoinoaaiiy, ye? aeei?enoiaothoueny a ee?i?/i?e i?aeoeoe?. Eeth/ia? neiaa: ?ioa?eo i?iea?aea, ee?i?ea, ciia iae?ico, ia?ooi?i?aai?/i? niieoee, ia?ooi?ai, neiiaoi-aae?aiaeiaa nenoaia, a?noai?i, na?ioii?i, a?aeaeaeai? ?acoeueoaoe. AIIIOAOeEss *a?eaniaa I. A. Iniaaiiinoe oa/aiey eioa?eoa ieiea?aea i?e eniieueciaaiee ia?ooi?aia. - ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.11 - ea?aeeieiaey. - Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Oa?ueeia, 1999. Aeenna?oaoeey iinayuaia iainiiaaieth aiciiaeiinoe e oeaeaniia?aciinoe eniieueciaaiey a eiiieaeniie oa?aiee ino?iai ia?eiaea eioa?eoa ieiea?aea iaaaiiaeiaeiiaiai ia?aiin/eea eenei?iaea - ia?ooi?aia (oa?iaoeaaoe/aneay oe?ia “Ia?ooi?ai”, ?inney). N yoie oeaeueth ianeaaeiaaii 82 aieueiuo EI, 22 ec eioi?uo a 1 nooee i?iaaaeaia eioocey i?aia?aoa. Eco/aii aai aeaenoaea ia eeeie/aneia oa/aiea ino?iai EI, aaciaue ninoaa e?iae e eeneioii-iniiaiia ninoiyiea, aeeiaieeo yeaeo?ioeceieiae/aneeo iieacaoaeae, ?aaeoeeth neiiaoi-aae?aiaeiaie, aenoaiei-?aaeoeaiie e na?ioiieia?ae/aneie nenoai, iinoeioa?eoiia ?aiiaeaee?iaaiea ieiea?aea. Aeieacaii, /oi ia?ooi?ai oiaiueoaao aeiienaieth e oeaiaaoth aeiieneth. Onoaiiaeaii, /oi aaaeouei yaeyaony aeeyiea i?aia?aoa ia aaee/eio eiia/iie ciiu iae?ica ieiea?aea. Oiaiueoaiea ?acia?ia iia?aaeaeaiiiai ieiea?aea iaoneiaeei aieaa iieiia ainnoaiia-eaiea aai ooieoeee, /oi iiaeoaa?aeaeaaony iaiueoae oyaeanoueth na?aea/iie iaaeinoaoi/iinoe o yoeo iaoeeaioia ia anao yoaiao iaaethaeaiey. I?aaeeiaeaiu ?aeiiaiaeaoeee ii aai i?eiaiaieth, eioi?ua eniieuecothony a eeeie/aneie i?aeoeea. Eeth/aaua neiaa: eioa?eo ieiea?aea, eeeieea, ciia iae?ica, ia?ooi?i?aaie/aneea niaaeeiaiey, ia?ooi?ai, neiiaoi-aae?aiaeiaay nenoaia, aenoaiei, na?ioiiei, ioaeaeaiiua ?acoeueoaou. SUMMARY Cherkasova OG Peculiarities of current myocardium infarction with using Perftoran. -Manuscript. Thesis for a candidat’s degree of medical sciences by a speciality 14.01.11 - cardiology.- Kharkov state medical university, Kharkov, 1999. The dissertation is devoted to the problem of optimization of the treatment of the patients with acute myocardium infarction. The features of its current at the first day after administration a non-hemoglobin oxygen carrier - Perftoran (“Perftoran”, Russia) were investigated. The ability of perfluorocarbons emulsions to reduce hypoxia of cell structures and by that to limit a zone of irreversible damages in myocardium, proved to experiments, has become the basis of this investigation. Perftoran improved delivery of oxygen to myocardium; increased coronary flow because of diminish viscousity of blood; diminish ischemic damages because of cardioprotector action. The purpose of work: to prove an opportunity and expediency of administration of non-hemoglobin carrier of oxygen - Perftoran - in complex therapy myocardium infarction by an estimation of results of treatment in nearest and long-term periods. We have investigated 82 patients with myocardium infarction (men, 38-60 years), who was admitted to the hospital within the first 6 hours from the pain accident.Two variants of initial therapy were used: in the first group (60 men, 54,71,9 years) – administration of nitroglycerini, -blockers, desagregation agents, nitroglycerini of long-term action; in the second group (22 men, 55,21,3 years) - intravenous drip administration of “Perftoran” in a total amount 4-5 ml/kg within the first day, after that we performed the same therapy like in the first group. The investigation was hold during the year. 45 patients from the first group and 18 patients from the second group were investigated in one year. There were 40 healthy men the same age in control group. Apart from the clinical data the activity of enzymes (CK, AST), markers of blood oxygen transport function (pO2, pCO2, pH, BE, StO2 in venous and arterial blood), parameters sympatho-epinephrine, histamine-reactive and serotonine systems on the bases of daily excretion were studied.ECG was performed daily within first 7 days and after that once a week. According to ECG we investigated estimated infarction size (Aldrich H.R. 1988), final weight necrosis (Selvester R.H. 1985), saved myocardial weight. Daily monitoring ECG were performed in 1-3 day of disease. An echoCG were studied before leaving the hospital. Clinical observation has shown that pain syndrome severity in first three days of disease was 3-4 times less in the Perftoran group than in the control group according to the total amount and contents of medication for its relief. In 17 of 22 patients of this group the ECG attributes of subacute phase formation have appeared two days earlier. It was established, that the main action of Perftoran was decreasing the final zone of necrosis myocardium, because saved weight of myocardium was twice as high as the first group (27.02,5 % and 12,51,1 % respectively). That has resulted to more complete restoration of left ventricular myocardial function on the bases of echo CG and clinical supervision. The data daily monitored ECG have revealed the temporary myocardial ischemia in half observed patients of both groups. The episodes of painless ischemia were registered in the second group only. The total daily duration of ischemia in the I group has appeared almost 3 times more.In the first day after use Perftoran we noticed the more favorable ratio between parts of sympathic nervous system and faster restoration up to a physiological level of parameters sympatho-epinephrine, histamine-reactive and serotonine systems. It’s can be estimated as the factor reducing tissue ischemia. The results of retrospective investigation testify, that after administration Perftoran we had more favorable current of postinfarction period. It’s expressed in smaller number of repeated myocardium infarction and lower degree of heart failure. These patients more often came back to work. It’s proved that the second group has more complete restoration of left ventriculum function, because of satisfactory contractility of myocardium of all patients. Disoders of diastolyc function was marked in 3 patients only. This research work has given the basis to consider, that the introduction Perftoran in complex therapy had positive influence on the nearest and long-term results of myocardium infarction treatment and to recommend its administration in the first day of disease. The practical recommendations for its application were offered. The results of research work were introduced into practical work of the Dnepropetrovsk Emergency Care Hospital and educational process of the Dnepropetrovsk State Medical Academy. Key words: myocardium infarction, perfluorocarbons emulsions, Perftoran, hypoxia, clinical current, zone of necrosis, sympatho-epinephrine system, histamine, serotonine.

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