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Особливості нейродинамічних порушень у осіб, що зазнали впливу іонізуючого випромінювання (за даними дослідження викликаних потенціалів головного мозк

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OA?E?ANUeEEE ?INOEOOO OAeINEIIAEAIIss E?EA??A

IIAI??EIA Ieaen?e A?eoi?iae/

OAeE 612.82+616.831]-008.6-073.786/.788. :614. 876.

INIAEEAINO? IAE?IAeEIAI?*IEO II?OOAIUe O IN?A,

UI CACIAEE AIEEAO ?II?COTH*IAI AEI?II?ITHAAIIss

(ca aeaieie aeine?aeaeaiiy aeeeeeaieo iioaioe?ae?a aieiaiiai iiceo)

14.01.15. – Ia?aia? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai

nooiaiy eaiaeeaeaoa iaaee/ieo iaoe

OA?E?A -1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Aei?i?iiao?ianuee?e aea?aeaai?e iaaee/i?e aeaaeai??,
IIC Oe?a?ie.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

i?ioani? eaoaae?e ia?aiaeo oai?ia Oeieueiee Aaea??e Ia?eiae/,

Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y.

Io?oe?ei? iiiiaioe:

Caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie, eao?aao Aea?aeaaii? i?ai??
Oe?a?ie,

aeieoi? iaaee/ieo iaoe, i?ioani? Aeoaaiei ?aaai?e A?eai?iae/,
Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, caa?aeoaa/ eaoaae?e
ia?aiaeo oai?ia.

aeieoi? iaaee/ieo iaoe, i?ioani? Iaca?aiei Aaaeei A?eai?iae/,
Aeiiaoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao, caa?aeoaa/ eaoaae?e
ia?aiaeo oai?ia.

I?ia?aeia onoaiiaa: IAe? aa?iioieia?? AII Oe?a?ie, aa??ao?e/iee oeaio?,
i.Ee?a.

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 24 ” aa?aciy 1999?. i 10.00 aiaeei?
ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae.64.609.01. i?e
Oa?e?anueeiio ?inoeooo? oaeineiiaeaiiy e?ea??a (310176, i. Oa?e?a, aoe.
Ei?/aa?ioe?a,58).

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Oa?e?anueeiai
?inoeoooo oaeineiiaeaiiy e?ea??a , aae?ana: 310176, i.Oa?e?a,
aoe.Ei?/aa?ioe?a,58.

Aaoi?aoa?ao ?ic?neaiee “__24__” ethoiai 1999?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi?. iaae. iaoe ?.A.A??ai?iaa.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie

Ca aeaieie iaoe?iiaeueiiai ?aa?no?a, aiane?aeie aaa??? ia
*i?iiaeeuenuee?e aoiii?e aeaeo?e/i?e noaioe?? (*AAN), iino?aaeaeaei
a?eueoa o?ueio i?eueeii?a aeeoae?a Oe?a?ie. Iaooeeueiee ??no ca`ycaii? c
aaa???th caoai?thaaiino? ? ?ioaa?aeueiei ?acoeueoaoii iie?oaeoi?iiai
aieeao eaoano?ioe ? no?eeeo oaiaeaioe?e c?inoaiiy caoai?thaaiino? ii
an?e e?a?i? (A.?.Iyao ? ni?aaao., 1995-1998, A.A.Iaca?aiei,1995,
I.A.Aieioei,1997, ?.A.Aeoaaiei,1995, I.A.Caeanaiei,1998).

Iaaaoeaiee aieea aaa??? ia ae?enia ? iaeaooi? iieie?iiy, ii nooiai?
iaiaaiino? a?ae’?iieo /eiiee?a, iaaaaeo? oaiiiai aenaa?aa
(A.?.?iiaiaiei, 1995), i?e oeueiio ianooaae eaoano?ioe ia iathoue
aiaeia?a o na?oia?e ?noi??? (A.A.Aa?aaie, 1990).

Ia?aia? ? ineo?/i? oai?iae caeiathoue ae?oaa ? o?ao? ?aiaia? i?noey a
no?oeoo?? caoai?thaaiino? e?ea?aeaoi??a aaa??? (EA) (A.?.Iyao ?
ni?aaao., 1995-1998), niiaoe/ia iaoieia?y a ieo iae?aaoii
noi?iaiaeaeo?oueny ii?ooaiiyie c aieo oeaio?aeueii? ia?aiai? nenoaie, ui
aenoaa? ineoiiaa?ieia?/ia aeine?aeaeaiiy a ?ic?yae iaeiiai c
i??i?eoaoieo iai?yie?a o aea/aii? oe??? iaoieia??.

?aeeia oi/ea ci?o ia ?icaeoie ?aae?aoe?eii? iaoieia?? a aeaiee /an
inoaoi/ii ia noi?ioaaeany. ?nio? aeae?eueea oai??e, ui i?aee?aneththoue
cia/aiiy ie?aieo aoai?a ?icaeoeo ?aae?aoe?eiiai iiciaaiaco – oaeeo, ye
ia?aeiiee ?icaeoie ?aae?aoe?eii? aioeaoaeiiao??, iaoieia?y noaeeiiiai
??/eua a ?acoeueoao? ia?aeiii? ae?? ?ii?coth/eo aei?ii?ithaaiue (?A),
ii?ooaiiy ?ioiii? a?aeiia?ae?, iaoieia?y ieenii-a?aeaoaeiaieo i?ioean?a
? ?ioa. I?ine?aeaeo?oueny iaoiaaiaoe/iee ca’ycie aeec?aaoeyoe??
iae?iiaeueii? aeoeaiino?, iaoieia?? oeaio?aeueii? ia?aiai? nenoaie ia
an?o ??aiyo, ?c ?icaeoeii iaa?ieia?/ii?, niiaoe/ii?, noaeeiii? iaoieia??
(A.?.Iyao,1998, E.I.Eiaaiianueeee,1998, ?.A.Aeoaaiei,1997,
I.A.Aieioei,1997). Anoaiiaeaii, ui ?icaeoie ia?aeiieo ?aae?aoe?eieo
aioeaoaeiiao?e aeieea? i?e aeicao ?ii?coth/eo aei?ii?ithaaiue, ui
ia?aaeuothoue 50 ?aioaai (I.A.Caeanaiei,1997, I.A.Aieioei,1997,
K.Brennan,1995, A.Kennedy 1995), ui aeeeth/a? iaeiioaeoi?iee iaoai?ci
?icaeoeo aioeaoaeiiao?e o e?ea?aeaoi??a aaa???, ye? iaea?aeaee iaio?
aeice.

Iienaiee i?ia?aae??ioiee ieei ?aae?aoe?eii? iaoieia?? (A.?.Iyao ?
ni?aaao., 1995-1998, E.I.Eiaaiianueeee, 1998, A.I.A?a?anueea, 1997),
aeaoae?ciaaia ae?y aoi?eiieo iaoai?ci?a ?aae?aoe?eiiai iiciaaiaco
(I.A.Aieioei ? ni?aaao.,1995-1996, N.A.Aa?anueeei, 1996, A.I.*oi??eia ?
ni?aaao., 1997, A.?.Aeaaeaeia,1995). A aeaiee /an aeinoaoiuei iiaii
aea/ai? iaoai?cie ?aae?aoe?eieo iae?ic?a ia?aiai? oeaieie, iaoieia??
aiaeioae?th, caiono?iiy ? ca?aei?iiy i?e?ieai?ey?iiai ??/eua i?e ae??
aenieeo aeic ?ii?coth/eo aei?ii?ithaaiue (A.?.Iyao,1998,
E.I.Eiaaiianueeee,1998, R.Cicciarello,1996, I.Lamproglou,1995,
G.T.Gobbel,1992). Aea ae?y iaeeo aeic ?A ia nenoaiiiio ??ai?, iniaeeai o
a?aeaeaeaiiio ia??iae?, ci?ia oa?aeoa?o iae?iiaeueiiai ?aaaoaaiiy
aeine?aeaeaia iaaeinoaoiuei.

Aea/aiiy ?aae?aoe?eiiai iiciaaiaco, ye ?aeeiiai eiiieaeniiai
iie?oaeoi?iiai i?ioeano, c aecia/aiiyi eiie?aoieo iaoai?ci?a
iaoiaaiaoe/ieo eaiie ?icaeoeo iae?iiaeueii? ? oea?aa?iaaneoey?ii?
iaoieia??, oiia ooai?aiiy iaoieia?/ieo ii?i/ieo e?e (circulus vitiosus)
(A.?.Iyao ? ni?aaao.,1995-1997), ia iiaeia aaaaeaoe caaa?oaiei.

Ia?niaeoeai?noue aeine?aeaeaiue o aeaiiio iai?yieo aecia/a?oueny
iiaeeea?noth anoaiiaeoe ae?aaiinoe/i? e?eoa??? iaoieia?/ieo
iae?iaeeiai?/ieo noai?a ? ?ic?iaeoe i?eioeeie e?eoaaeueii? ei?aeoe??.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie

?iaioa aeeiiaia a ?aieao aea?aeaaii? iaoeiai-aeine?aeii? oaie :
“Aeine?aeaeoaaoe i?e/eie ? iaoai?cie ii?acee ? a?aeiiaeaiiy
aaeaioaoe?eieo nenoai i?aai?cio ethaeae, ui ciaoiaeyoueny a cii?
a?ae/oaeaiino?”, ? ? i?iaeiaaeaiiyi oaie aeine?aeaeaiiy aieeao
?ii?coth/eo aei?ii?ithaaiue ia oeaio?aeueio ia?aiao nenoaio,
?ic?iaethaaio iaoeiaei oeaio?ii ?aae?aoe?eii? iaaeeoeeie AII Oe?a?ie ?
eaoaae?ith ia?aiaeo oai?ia Aei?i?iiao?ianueei? aea?aeaaii? iaaee/ii?
aeaaeai?? (iiia? aea?ae?a?no?aoe?? N0196U010195).

Iaoa aeine?aeaeaiiy Ioe?iea iniaeeainoae oi?ioaaiiy ? ?icaeoeo
iae?iiaeueieo ? iae?iaeeiai?/ieo ii?ooaiue no?oeoo? oeaio?aeueii?
ia?aiai? nenoaie ? ?o ca’yceo ?c noaeeiieie ?iceaaeaie a in?a, ui
caciaee aieeao ?ii?coth/eo aei?ii?ithaaiue.

Caaea/? aeine?aeaeaiiy

1. Aea/eoe ee?i?/i? ? iae?iaeeiai?/i? iniaeeaino? ii?ooaiue
oeaio?aeueii? ia?aiai? nenoaie a o/aniee?a e?ea?aeaoe?? iane?aee?a
aaa??? ia *AAN.

2. Aecia/eoe oa?aeoa? iaoieia?/ieo ci?i iae?iiaeueii? aeoeaiino?,
nooi?iue aeac?ioaa?iaaiino? “aei?noeeo” ? “aio/eeo” eaiie ?aaoeyoe??
iiceiai? ae?yeueiino?.

3. Ioe?ieoe ca’ycie iae?iaeeiai?/ieo ii?ooaiue ?c ?icaeoeii iiceiai?
noaeeiii? iaaeinoaoiino?.

4. Aecia/eoe ae?aaiinoe/ii cia/ei? e?eoa??? iae?iaeeiai?/ieo,
aaiiaeeiai?/ieo ?iceaae?a, eiiiainaoi?i? iiaeeeaino? oeaio?aeueii?
ia?aiai? nenoaie ? i?eioeeie i?iaaaeaiiy e?eoaaeueii-i?io?eaeoe/ieo
caoiae?a a in?a ?c iane?aeeaie ?ii?coth/eo aei?ii?ithaaiue .

Iaoeiaa iiaecia Ca aeiiiiiaith aaaaoioaeoi?iiai nenoaiiiai
aiae?co, ia iniia? eiiieaeniiai aea/aiiy iae?iaeeiai?ee ? aaiiaeeiai?ee
a in?a, ye? iaea?aeaee iae? ? na?aaei? aeice ?ii?coth/eo
aei?ii?ithaaiue, aecia/ai? oa?aeoa?i? ?ene iae?iiaeueii? aeoeaiino?, ui
aecia/athoue ?aae?aoe?eiee iiciaaiac.

Aia?oa iienai? oeie ?aaeoe?? oeaio?aeueii? ia?aiai? nenoaie (OeIN) o
e?ea?aeaoi??a aaa??? i?e ooieoe?iiaeueieo ? oa?iaeieia?/ieo i?iaao –
aeni?aneaiee, oi?i?aeiee, aeai?aneaiee. Iaa?oioiaaii ioe?ieo ci?i
aiie?ooaee aeeeeeaii? aeoeaiino? (AA), ye iieacieea, ui a?aeaeaa?
oaeaee?, i?enoinoaaeuei? ?aaeoe?? OeIN, ? oei/aniaeo iieaciee?a, ye?
a?aeaeca?eaeththoue a?eueo ?noioi?, no?ee? oa?aeoa?enoeee
ooieoe?iioaaiiy OeIN, ii?ooaiiy yeeo oa?aeoa?eco? iieiieo eiiiainaoi?ieo
iiaeeeainoae.

Noi?ioeueiaaii iieiaeaiiy i?i oi?ioaaiiy ?iaeea?aeoaeueiiai
“iae?iaeeiai?/iiai ii?o?aoo” o e?ea?aeaoi??a aaa???.

Aecia/aii aoaie ? oiiae oi?ioaaiiy a e?ea?aeaoi??a aaa??? no?eeeo
aeec?aaoeyoi?ieo ?aoeaeoi?ieo ca’yce?a, ui i?ecaiaeyoue aei ?icaeoeo
i?ia?aae??ioiiai ieeio ?aae?aoe?eii? iaoieia??.

I?aeoe/ia oe?ii?noue ?iaioe

Ia iniia? aeyaeaieo no?eeeo ca’yce?a niiioaiii?, aeeeeeaii? aeoeaiino?
OeIN ? oea?aa?aeueii? aaiiaeeiai?ee, iaa?oioiaaia aeei?enoaiiy iiaeo
ae?aaiinoe/ieo e?eoa???a i?e iae?io?c?ieia?/ieo aeine?aeaeaiiyo o
e?ea?aeaoi??a aaa??? ia *AAN.

Cai?iiiiiaaii ioe?ieo iieaciee?a ae?yeueiino? OeIN ia ??ai? o?aoeiieo
ei?eiaeo aiae?caoi??a ca cia/aiiyi eiao?oe??ioa iie?iiaeaeueieo
a?aeiioaiue (Eia).

I?iaaaeaiiy i?ia, ui aeoeaothoue, c aecia/aiiyi oei?a ?aaeoe??
-aeni?aneaiiai, oi?i?aeiiai, aeai?aneaiiai, aeicaiey? ioe?ieoe nooi?iue
oea?aa?aeueii? eiiiainaoe??, ui iiaeeeai aeei?enoiaoaaoe a eiio?ie? ca
e?eoaaeueiei i?ioeanii.

Aecia/aiiy caeaaeiinoae ?aae?aoe?eiiai iiciaaiaco a?ae oi?ioaaiiy
no?eeeo aeec?aaoeyoi?ieo iae?iiaeueieo ca’yce?a aecia/a? iia? i?aeoiaee
aei ei?aeoe?? iaa?ieia?/ii? iaoieia?? a e?ea?aeaoi??a aaa??? c
canoinoaaiiyi iaoiaeee aieeao ia iaoieia?/iee iae?iiaeueiee iaooa?i.

?ic?iaeaia a oiae? aeine?aeaeaiiy iaoiaeeea aaaaoioaeoi?iiai aiae?co, ui
aeeth/a? eiii’thoa?io i?ia?aio ?a?no?aoe?? ? ii?aoethaaiiy iae?iiaeueii?
aeoeaiino? ? oea?aa?aeueii? aaiiaeeiai?ee, iiaea aooe aeei?enoaia a
oiae? iaa/aeueiiai i?ioeano ? a oiiaao iaa?ieia?/iiai noaoe?iia?o aai
iie?ee?i?ee, a ?iaio? aenia?oieo eii?n?e.

Ai?iaaaeaeaiiy ?acoeueoao?a iaoeiaiai aeine?aeaeaiiy a
e?eoaaeueii-ae?aaiinoe/iee ? iaa/aeueiee i?ioean cae?eniaii ia aac?
iaa?ieia?/iiai a?aeae?eaiiy iaeanii? e?ea?i? ?i. Ia/ieeiaa i.
Aei?i?iiao?ianueea, ia eaoaae?ao iaa?ieia?? Aeiiaoeueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo, Iaeanueei? aea?aeaaii? iaaee/ii? aeaaeai??,
Oa?iii?euenueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, Iieoaanueei?
Oe?a?inueei? noiiaoieia?/ii? aeaaeai??, iaoeiai-aeine?aeiiio ?inoeooo?
aa?iioieia?? AII Oe?a?ie (Ee?a), iaa?ieia?/iiio a?aeae?eaii?
Oe?a?inueeiai aea?aeaaiiai iaoeiai-aeine?aeiiai ?inoeoooo
iaaeeei-nioe?aeueieo i?iaeai ?iaae?aeiino? (Aei?i?iiao?ianuee).

Aeaeea?aoe?y iniaenoiai aianeo caeiaoaa/a o ?ic?iaeo iaoeiaeo
?acoeueoao?a Aaoi?ii aeena?oaoe?? naiino?eii aeeiiai?
aeine?aeaeaiiy c aea/aiiyi aeeeeeaii? ? niiioaiii? aeoeaiino? aieiaiiai
iiceo, oea?aa?aeueii? aaiiaeeiai?ee c canoinoaaiiyi iaoiae?a ?aia?ao??,
oeueo?acaoeiai? aeiiea?ia?ao??, aoi-aioeaoaeineii??, ?ic?iaeai? i?ia?aie
?a?no?aoe?? ? aiae?co aeaeo?iaioeaoaeia?ai ? ?iiaaeainia?ai, i?iaaaeaia
noaoenoe/ia ii?aoethaaiiy ?acoeueoao?a aeine?aeaeaiiy ? noi?ioeueiaai?
iniiai? iieiaeaiiy aeena?oaoe?eii? ?iaioe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe?? Iaoa??aee aeena?oaoe?eii? ?iaioe
aeiaaaeai? ? iaaiai?ai? ia iaoeiaeo eiioa?aioe?yo, c’?caeao,
neiiic?oiao:

Iaoeiai-i?aeoe/i?e eiioa?aioe?? “*a?iiaueue e caei?iauea /aeiaaea (10
eao iinea aaa?ee)” a i.Ee?a?, 1996., Iaoeiai-i?aeoe/i?e eiioa?aioe??,
i?enay/aii? 10-e ??/ieoe? aaa??? ia *AAN a i.Aei?i?iiao?ianueeo,1996.,
1-io Oe?a?inueeiio iaoe?iiaeueiiio eiia?an? iaa?iiaoieia?a ? ineo?ao??a
a i.Oa?eia?,1997., Iaoeiai- i?aeoe/i?e eiioa?aioe?? “?aaa?e?oaoe?y
oai?eo iioeeiai a?eo ?c caoai?thaaiiyie na?oeaai-noaeeiii? nenoaie ?
oea?aa?aeueiith iaoieia??th” a i.Ee?a?,1997., 1-io i?aeia?iaeiiio
neiiic?oi? “Noa??iiy ? oea?aa?iaaneoey?ia iaoieia?y” a i.Noaeae,1997.,
Iaeani?e eiioa?aioe?? e?ea??a-iaa?iiaoieia?a Aei?i?iiao?ianueei? iaeano?
(aa?acaiue 1998 ?.), 2-e I?aeia?iaei?e eiioa?aioe?? “Ioaeaeaiiua
iaaeeoeeineea iineaaenoaey *a?iiaueueneie eaoano?iou” a i.Ee?a?,1998.

Ioae?eaoe?? Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 15 iaoeiaeo
i?aoeue, ?c ieo /ioe?e noaoo? a oeaio?aeueieo aeo?iaeao, ca nieneii
aeaeaiue, ?aeiiaiaeiaaieo AAE, 11 i?aoeue a iaoeiaeo ca??ieeao ii
iaa?ieia?? ? iaoa??aeao i?aeia?iaeieo eiioa?aioe?e.

No?oeoo?a ? ianya ?iaioe Aeena?oaoe?y aeeeaaeaia ia 133 noi??ieao
iaoeiiieniiai oaenoo aac a?aooaaiiy nieneo e?oa?aoo?e ? neeaaea?oueny c
anooio, iaeyaeo e?oa?aoo?e, 5 ?icae?e?a aeanieo aeine?aeaeaiue ?
iaaiai?aiiy ?acoeueoao?a, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e ?
iieaae/eea e?oa?aoo?e. O aeena?oaoe?? 25 oaaeeoeue, 48 iaethie?a,
a?ae?ia?ao?y aeeth/a? 249 aeaea?ae, c ieo 71 ?iicaiia.

CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy

I?iaaaeaii ianoaaeaiiy 124 /ieia?e?a, o/aniee?a e?ea?aeaoe?? aaa??? ia
*AAN. 37 EA aoee ianoaaeai? iiaoi?ii c ?ioa?aaeii a iaeei ??e.
Aeieoiaioiaai? aeice ?aae?aoe?eiiai iaaaioaaeaiiy neeaaeaee a?ae 5 aei
29,5 nA?ae. O/anoue o e?ea?aeaoe?? aaa??? ia *AAN i?eiaaeaea ia 1986 ?
1987 ?iee. A?e EA, ui ianoaaeeeenue, ciaoiaeeany a iaaeao a?ae 28 aei 49
?ie?a. Na?aaei?e a?e neeaa 37,4 ?ieo.

Eiio?ieueia a?oia neeaaeaeany c 35 /ieia?e, ui ia iaee eiioaeoo c ?A,
ii??aiyiiai a?eo. EA a oiae? ee?i?/iiai ianoaaeaiiy, i?iaaaeaiiy
noaiaea?oieo ae?aaiinoe/ieo aeine?aeaeaiue, ?icae?eai?, ii i?eeiyo?e
eeaneo?eaoe??, ia aea? a?oie.

Ia?oo a?oio neeaee 69 EA c ee?i?/ieie iciaeaie aaaaoaoeaii- noaeeiii?
aeenoii?? (ANAe), ?c e?eciaei ? ia?iaiaioiei ieeiii.

Ae?oaa a?oia neeaaeaeany c 55 EA c iciaeaie ?aiiueiai oea?aa?aeueiiai
aoa?ineea?ico (?OeA). A?oia EA c ?OeA aoea ee?i?/ii iaiaeii??aeiith, ?
?icae?eaia ia aea? i?aea?oie – oai?? c ?OeA ? ii/aoeiaeie i?iyaaie
iaaeinoaoiino? e?iaiia?ao iiceo (IIIEI) – 31 /ieia?e, ? oai?? c ?OeA ?
iciaeaie aeenoee?eoeyoi?ii? aioeaoaeiiao?? (AeA)- 24 /ieia?ea.

Ii?yae c iiaeeaeaiei ee?i?/iei ianoaaeaiiyi i?iaiaeeeanue ?a?no?aoe?y
ci?iaeo aeeeeeaieo iioaioe?ae?a (CAI), niiaoi-naini?ieo aeeeeeaieo
iioaioe?ae?a (NNAI), neooiaeo oaeaii-ei?oeeaeueieo (NOEAI), neooiaeo
aeeeeeaieo iioaioe?ae?a iiceiaiai noiaao?a (NAIIN) ia niaoe?ae?ciaaiiio
eiiieaen? O.T.E. Biomedica, ae?iaieoeoaa ?oae??, iiaeaeue 2362.
I?iaiaeeeinue ona?aaeiaiiy neaiaeo, i?ae yeei ?icoi??oueny ae?eaiiy
iaea?aeaieo a ?acoeueoao? eiaa?aioiiai iaeiie/aiiy cia/aiue aiie?ooaee
ia e?euee?noue noiaoe?e.

?a?no?aoe?? CAI cae?enithaaeenue o a?aeaaaeaiiyo 10-20 ii i?aeia?iaei?e
eeaneo?eaoe??, iiiiiiey?iei caniaii. Oioiniaeaoe iiooaei?noth 1iAon,
o?eaae?noth 10 ien iiaeaaaeeny ca aeiiiiiaith ?cieyoe?eieo i/ie i?e
cae?eoeo iia?eao. *anoioa noeioeyoe?? -1 na?oeiaee neaiae ca 1,5
naeoiaee. E?euee?noue ona?aaeiaiue – 50. Ia??iae ?a?no?aoe?? CAI
neeaaeaa 500 in, aa?oiy nioaa o?eueo?aoe?? -200 aoe, o?eueo? ieaeiuei?
/anoioe -0,53 Aa?oe (aoe).

Aeine?aeaeaiiy NNAI ? NOEAI cae?enithaaeiny i?e ?aeaioe/ieo CAI
ia?aiao?ao /anoioieo o?eueo??a ? iineeaiiy. Noeioeyoe?y i?iaiaeeeany a
cii? ?iia?aaoe?? n. medianus aeaeo?e/ieie ?iioeuenaie 50 iA, o?eaae?noth
0,1 in, /anoioith 1 o 1,5n. c ia?aaeaa/aiei aia?aoiei ?aaeeiii
i?eaeooaiiy a?oaoaeo?a.

I?e aea/aii? NOEAI, a iaaooieee iiii- ? a?iao?aeueii iiaeaaaany caoeiaee
ueaieue, /anoioiei niaeo?ii a?ae 5 aei 20000 aoe. O?eaae?noue noeioe?a
neeaaeaea 0,1in, ?ioaineai?noue – ia 30 aeA aeua neooiaiai ii?iao.

Aeine?aeaeaiiy NAIIN cae?enithaaeiny a ?aaeei?: /anoioa noeioeyoe?? -10
aoe. *anoioi? o?eueo?e – aa?oi?e 20 Eaoe, ieaei?e -53 aoe. O?eaae?noue
noeioe?a neeaaeaea 0,1 in., ?ioaineai?noue -30 aeA aeua neooiaiai
ii?iaa.

I?iaiaeeeeny i?iae c a?ia?aaioeeyoe??th, i?eeiiii oano-aeice
i?o?iae?oea?eio ? ao?i?cieo, i?iaith ?ani??aoi?ii? ianiaoeeo?/ii?
aeoeaaoe?? c ia?aie iaoaoe?iiai nie?oo (NH3OH).

I?e ?a?no?aoe?? AAA aeei?enoiaoaaeany aia?aoo?a – nenoaia ia aac? IBM
PCAT ? 10- eaiaeueiiai aeaeo?iaioeaoaeia?aoa Bioscript ae?iaieoeoaa VEB
Messgeratewerk. ?a?no?aoe?y i?iaiaeeeany ii 8 eaiaeao ?c iiaeaeueoei
ii?aoethaaiiyi niaeo?aeueii? /anoioe, iiooaeiino?, ea?ooaaiiyi
iieaciee?a ca aeiiiiiaith i?ia?aiiiai caaacia/aiiy, ?ic?iaeaiiai a oiae?
aeine?aeaeaiiy.

?aiaioeaoaeia?ao?y (?AA) i?iaiaeeeany ia 4-o eaiaeueiiio ?aia?ao? ?4-02
c eiii’thoa?iei caienii ? ii?aoethaaiiyi iieaciee?a o ?ic?iaeai?e
i?ia?ai? ?a?no?aoe?? ?AA. Oaeiae i?iaaaeaia yoi- aioeaoaeineii?/ia
aeine?aeaeaiiy ia aia?ao? AN-20. Aeey ioe?iee noaio iaa?no?aeueieo
noaeei aeei?enoaii iaoiae oeueo?acaoeiai? aeiiea?ia?ao?? (OCAeA) ia
aeaa?oiao?? Ae-800 o??ie “Medata AB”, ae?iaieoeoaa Oaaoe??.
Aeine?aeaeoaaeeny ea?ioeaeiee ? aa?oaa?i-aac?ey?iee aanaeie, c
i?iaaaeaiiyi eiii?an?eieo i?ia.

?ACOEUeOAOE AeINE?AeAEAIUe ? ?O IAAIAI?AIIss

I?iaaaeaia aeine?aeaeaiiy aeyaeei ianooiia: NAIIN o EA c iciaeaie ANAe
oa?aeoa?ecoaaeenue oaiaeaioe??th aei ca?eueoaiiy eaoaioieo ia??iae?a
(EI) 2-7 eiiiiiaio?a, ?c i?i?iaeueiith noaoenoe/iith aeaa?aoe??th
iieaciee?a EI. A?aecia/aia cia/ia ?iaeea?aeoaeueia aa??aaaeuei?noue
aiie?ooaeieo iieaciee?a NAIIN. Iiaoi?i? ?a?no?aoe?? NAIIN /a?ac ??e (o
37 oai?eo) aeyaeyee iaeiioeii? ca oi?iith, EI, aiie?ooaeith (A), ?
?ioeie iniaeeainoyie iioaioe?aee a EA. O e?ea?aeaoi??a aaa??? c ?OeA ?
IIIEI a??ia?aeii cieaeaia A NAIIN (oaae. 1), i?aeieeia? ?ioa?aaee 2-5,
1-3 (p0,05).
Iieacieee A a??ia?aeii cieaeai? ii I1, I1, I3, I4, I4 eiiiiiaioao.

O EA c ?OeA a?aecia/aeiny ia?inoath/a /enei aeaoi?iaoe?e, aneiao??e,
aeenoii?/iiai ?iciiae?eo A, iiyae noi?iii?o aino?i-aieiiaeo ?eoi?a.

Aeine?aeaeaiiy niiioaiii? a?iaeaeo?e/ii? aeoeaiino? EA i?iaiaeeeiny o
aca?iica’yceo AI ? AAA ia ei?eiaiio ? noiaao?iaiio ??aiyo ? aeyaeei
iayai?noue aeinoia??iiai ca’yceo i?ae iieacieeaie AI ? AAA aeoeaiino?.
A?eueo aenie? eiao?oe??ioe ei?aeyoe?? io?eiai? i?e c?noaaeaii? A i?ci?o
eiiiiiaio?a AI ?c A aeueoa- aeoeaiino? AAA. I?ine?aeaeo?oueny
aeinoia??ia caeaaei?noue i?ae cia/aiiyie aiie?ooaee I2 ? I2 oaeeue AI ?
ca?eueoaiiy niaeo?aeueii? iiooaeiino? aeaeueoa- oaeeue ia oii? cieaeaiiy
oaoa – aeoeaiino?.

Ianoaaeaiiy a aeeiai?oe? ei?eiaeo AI iieacaei cia/io noaa?euei?noue o
/an? (ca ia??iae a?eueoa 1 ?ieo), oa?aeoa?ii? ea?oeie aeeeeeaii?
iie?iiaeaeueii? aeoeaiino?. Oae, i?e ?a?no?aoe?? AI o EA c ia??iaeii o
12 i?nyoe?a e?ea? AI iiaoi?thaaeeny c? caa?aaeaiiyi caaaeueiiai
iaethiea, ?ici???a EI, oa?aeoa?ieo aca?iia?aeiinei A i?e?a AI ?
ae?aciino? ie?aieo aeaiaio?a. Iia??oaiiy iieaciee?a AI a?aecia/aeiny a
?ac? iiyae iaaaoeaii? neiioiiaoeee.

Ia i?aenoaa? iienaieo aeaieo noi?ioeueiaaia iieiaeaiiy i?i iayai?noue
?iaeea?aeoaeueiiai iaooa?ia aai oa?aeoa?o ?aaaoaaiiy a EA ia *AAN, ui ?
noaa?eueiith oa?aeoa?enoeeith aai iae?iaeeiai?/iei ii?o?aoii, ia?ea?ii,
?iaeea?aeoaeueiei ia?acii ?aaaoaaiiy. Aeyaeaii aeinoia??i? ei?aeyoe?ei?
ca’ycee (p

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