?INOEOOO AIAeIE?EIIEIA?? OA IAI?IO ?A*IAEI

?i. A.I.Eii?na?aiea AII Oe?a?ie

AI?IIEI Aiae??e Aiaoie?eiae/

OAeE 616.379-008.64.-085:621.039.586-051

INIAEEAINO? EE?I?*IIAI IA?AA?AO OA E?EOAAIIss OeOE?IAIAI Ae?AAAOO A

O*ANIEE?A E?EA?AeAOe?? IANE?AeE?A AAA??? IA *I?IIAEEUeNUeE?E AAN

14.01.14 — aiaeie?eiieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1998

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao? ?i.

I.I.Aiaiiieueoey, IIC Oe?a?ie

IAOEIAEE EA??AIEE:

aeieoi? iaaee/ieo iaoe, i?ioani? Aiaeia? Iao?i

Ieeieaeiae/, Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i.

I.I.Aiaiiieueoey, caa?aeoaa/ eaoaae?e aiaeie?eiieia??

IO?Oe?EI? IIIIAIOE:

aeieoi? iaaee/ieo iaoe, i?ioani? Ieeoea Oa?an Aeaieniae/,

Iaoe?i iaeueiee iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey,

caa?aeoaa/ eaoaae?e i?iiaaeaaoeee aioo??oi?o oai?ia N 2

aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee

Eo/eoeueeee ?aaai Aaneeueiae/, ?inoeooo aiaeie?eiieia?? oa

iai?io ?a/iaei ?i. A.I.Eii?na?aiea AII Oe?a?ie, caa?aeoaa/

a?aeae?eii ee?i?/ii? aiae?ieia??

I?IA?AeIA ONOAIIAA: ?aaii-O?aie?anueea aea?aeaaia

iaaee/ia aeaaea i?y, eaoaae?a aiaeie?eiieia??, IIC Oe?a?ie, i.

?aaii-O?aie?anuee

Caoeno a?aeaoaeaoueny «17» eenoiiaaea 1998 ?. i 13.00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae.26.558.01 c aiaeie?eiieia??
a ?inoeooo? aiaeie?eiieia?? oa iai?io ?a/iaei ?i. A.I.Eii?na?aiea AII
Oe?a?ie (254114, Ee?a-114, aoe. Aeoai?iaenueea, 69).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeoooo
aiaeie?eiieia?? oa iai?io ?a/iaei ?i. A.I.Eii?na?aiea AII Oe?a?ie
(254114, Ee?a-114, aoe.. Aeoai?iaenueea, 69).

Aaoi?aoa?ao ?ic?neaiee “15” aeiaoiy 1998 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Eaeeinueea E.I.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie. Oeoe?iaee ae?aaao (OeAe) ? iaeiei c iaea?eueo
?iciianthaeaeaieo caoai?thaaiue. E?euee?noue oai?eo ia ae?aaao neeaaea?
aeecueei 4% ? a inoaii?e /an o anueiio na?o? i?ia?aneaii ca?eueoo?oueny
[AIIC, 1994]. I?iaeaia OeAe ? iaaecae/aeii aeooaeueiith aeey Oe?a?ie,
ine?eueee ia ii/aoie 1996 ?ieo e?euee?noue oai?eo ia ae?aaao neeaaeaea
a?ey 900 oen. in?a [I.Ae.O?iiueei c? ni?aaao., 1996]. Ai?aeai?ieia?/ieie
aeine?aeaeaiiyie anoaiiaeaii, ui nia?oi?noue oai?eo ia OeAe, a 3 ?ace
ia?aaeuo? a?aeiia?aeio a caaaeuei?e iiioeyoe?? [A.N.Aoeiia e niaao.,
1983, 1989, 1994; I.E.Aaeaaieeei, 1994].

Aieea aeieia?/ieo ci?i iaaeieeoiueiai na?aaeiaeua ia ethaeeio ? iaei??th
c aeooaeueieo oai no/anii? iaaeeoeeie. Iioe?aiee ?ioa?an aei oeueiai a
inoaii?e /an aeeeeeaiee iane?aeeaie aaa??? ia *AAN. Aea/aiiyi aieeeo
“*i?iiaeeuenueeiai /eiieea” (**) ia i?aai?ci ethaeeie aeoeaii
caeiathoueny o anueiio na?o? [A.I.Aioiiia, 1989; C.K.Cassel et al.,
1989; Ph. Hubert et al., 1989]. Iaeaea 45,6% an?o iino?aaeaeaeeo a?ae
*i?iiaeeuenueei? eaoano?ioe i?iaeeaa? ia Oe?a?i? [TH.I.Ni?aeaiei c?
ni?aaao., 1993; AIIC, 1995; A.I.Na?aaethe, 1997].

Noai caei?ia`y in?a, ui caciaee aieeao iane?aee?a *i?iiaeeuenueei?
eaoano?ioe cia/ii iia??oeany [I.?.Aa?aiaiei, 1993, 1995; A.E.Aonueeiaa,
1993; J.Conredy, 1989]. Iai?oeeany no?eea oaiaeaioe?y c?inoaiiy na?aae
ieo caaaeueii? caoai?thaaiino? [A.A.?iiaiaiei, 1992; M.M.Quinn et al.,
1987; H.David Wegman, 1987], a?eueo aaaeeei noaa ia?aa?a aaaaoueio
caoai?thaaiue [A.O.Aic?aiia, 1996]. Ca inoaii? a?n?i ?ie?a e?euee?noue
caei?iaeo in?a na?aae o/aniee?a e?ea?aeaoe?? iane?aee?a *i?iiaeeuenueei?
eaoano?ioe ciaioeeanue o 4 ?ace [A.O.Aic?aiia, 1996].

Aeiaaaeaia ao?ieia?/ia ?ieue ?ii?coth/iai aei?ii?iaiiy a iaoieia??
ueoiaeaeii? caeice [A.Ae.*a?iia?ia c? ni?aaao., 1994; A.?.Aioeth?ei,
1995; O.?.Aiaaeaiiaa, 1996], ii?ooaii? noaoaai? noa?e [I.I.Aeai/aiei,
1994], o?aaeaii? a?iioaeaii-a?iio?ca?ii-iaaeie?ieeiai? nenoaie
[I.I.Eiaaeaiei, 1992, 1994, 1996; I.N.?ii-Aoaineaanueea c? ni?aaao.,
1994; O.I.Aacaa?oa c? ni?aaao., 1996]. Ieoaiiyi i?ney/i?iiaeeuenueeiai
ooeiaeaeaiiy aiaeie?eiiiai aia?aoo i?aeoeoieiai? caeice i?eae?ey?oueny
iaaeinoaoiy oaaaa, ui iaaii iia`ycaii c eiioeaioe??th
?aae?i?acenoaioiino? inoaiiuei? [I.Ae.O?iiueei e niaao., 1991]. Iaeia/a,
caoai?thaai?noue ia OeAe na?aae iaoeaioe?a caa?oaeiaieo
?aae?iioee?aeaie oa?eoi??e oa o/aniee?a e?ea?aeaoe?? iane?aee?a
*i?iiaeeuenueei? eaoano?ioe c?inoa? [A.E.E?aa/aiei e niaao., 1991;
A.I.Iaai?ia c? ni?aaao., 1994; TH.I.Ni?aeaiei, 1994; A.E.*aaai, 1994,
1996; A.E.Okeanov et al., 1996].

*a?ac oea ie ae??oeee aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao OeAe a
o/aniee?a e?ea?aeaoe?? iane?aee?a aaa??? ia *i?iiaeeuenuee?e AAN (OEIA)
? canoinoaaoe a e?eoaaii? oe??? eaoaai??? oai?eo iia? aoaeoeai? caniae
e?eoaaiiy — eaca?iioieoo?o oa aioa?ini?aoe?th, caaaeyee ?o iiceoeaiiio
aieeao ia ?ioiio nenoaio ? iai?i ?a/iaei [A.I.Ieoaeue/eoei, 1995, 1996;
?.?.Aaeaea, 1996; K.Lam et al., 1995].

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie. ieaiaie, oaiaie. Aeine?aeaeaiiy
aeeiiaii ca?aeii ieaio iaoeiai-aeine?aeieoeueei? ?iaioe Aieiaiiai
a?enueeiai-iaaee/iiai oi?aae?iiy II Oe?a?ie oa Oe?a?inueei?
a?enueeiai-iaaee/ii? aeaaeai??.

Iaoa ?iaioe. Ioe?iea aoaeoeaiino? eiiieaenii? oa?ai?? OEIA, oai?eo ia
?inoe?iicaeaaeiee oeoe?iaee ae?aaao (?COeAe) oa ?inoe?iiiacaeaaeiee
oeoe?iaee ae?aaao (?IOeAe), c canoinoaaiiyi aioa?ini?aoe?? ?
eaca?iioieoo?e.

Caaea/? aeine?aeaeaiiy:

1. Aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao ?COeAe oa ?IOeAe o o/aniee?a
e?ea?aeaoe?? iane?aee?a *i?iiaeeuenueei? eaoano?ioe.

2. I?iaanoe ii??aiyeueiee aiae?c ci?i iieaciee?a aoaeaaiaeiiai ?
e?i?aeiiai iai?i?a, noaio ia?aeeniiai ieeneaiiy e?i?ae?a (IIE),
no?oeoo?ii-ooieoe?iiaeueieo ii?ooaiue e?aiai oeoii/ea o oai?eo c ??cieie
oeiaie OeAe a caeaaeiino? a?ae iayaiino? *i?iiaeeuenueeiai /eiieea a
aiaiiac?.

3. Ioe?ieoe aieea o?aaeeoe?eii? i?ioeae?aaaoe/ii? oa?ai??, eiiieaenii?
oa?ai?? c aioa?ini?aoe??th ni?aaioii «Aoaeani?a» oa eaca?iith
aeoioieoo?ith ia ee?i?/i? iieacieee o OEIA, oai?eo ia ?COeAe oa ?IOeAe.

4. I?iaanoe ioe?ieo aoaeoeaiino? e?eoaaiiy oai?eo ia OeAe-OEIA c
canoinoaaiiyi aioa?ini?aoe?? ? eaca?iioieoo?e ia i?aenoaa? eiiieaenii?
ioe?iee ci?i iieaciee?a aoaeaaiaeiiai ? e?i?aeiiai iai?i?a, IIE,
no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea.

Iaoeiaa iiaecia ?iaioe. Aia?oa aea/ai? iniaeeaino? ee?i?/iiai ia?aa?ao
OeAe o OEIA. Iieacaii, oi aeey oai?eo ia ?COeAe-OEIA, a ii??aiyii? c
eiio?ieueiith a?oiiith, a?eueo oa?aeoa?ia eaa?euei?noue
ia?aa?aocaoai?thaaiiy c? noeeuei?noth aei a?iiae?eai?e, oa?aeoa?iee
/ano?oee ?icaeoie iae?iaia?iiao?e, iae?iiao?e, a?oa??aeueii?
a?ia?oaic??. A o oai?eo ia ?IOeAe-OEIA aei oeueiai i?e?aeio?oueny a?eueo
eaa?eueiee ia?aa?a oai?iae c? noeeuei?noth aei eaoiaoeeaeico, /ano?oee
?icaeoie aeaeiiiainaoe??, aoi?eiii? noeueoai?eai?aeii? ?acenoaioiino? oa
i?e?iaia?iiao??.

Aia?oa aeyaeai? iniaeeaino? aoaeaaiaeiiai, e?i?aeiiai iai?i?a oa
aeoeaiino? IIE o oai?eo ia OeAe-OEIA. Oae o oai?eo ia ?COeAe
a?aei?/aeenue cia/i?o? ii?ooaiiy, a ii??aiyii? c eiio?ieueiith a?oiith
oai?eo, aoaeaaiaeiiai iai?io oa IIE. A o oai?eo ia ?IOeAe — cia/i?o?
ii?ooaiiy aoaeaaiaeiiai ? e?i?aeiiai iai?i?a.

Aia?oa i?iaaaeaii aea/aiiy no?oeoo?ii-ooieoe?iiaeueieo ci?i e?aiai
oeoii/ea na?oey o OEIA, oai?eo ia OeAe. Iieacaii, ui o oeeo oai?eo
a?aei?/aeenue a?eueo cia/i?, i?ae a eiio?ieuei?e a?oi?, ii?ooaiiy
nei?ioeeai? caeaoiino? e?aiai oeoii/ea, ye? cia/i?o? o oai?eo ia ?IOeAe.

Aia?oa aea/aia aoaeoeai?noue eiiieaenii? oa?ai?? c aioa?ini?aoe??th
ni?aaioii «Aoaeani?a» ? eaca?iioieoo?ith o oai?eo ia OeAe-OEIA.
Aeieacaia ?o aoaeoeai?noue, yea coiiaeaia ii?iae?coth/ei aieeaii ia
aoaeaaiaeiee, e?i?aeiee iai?ie oa no?oeoo?ii-ooieoe?iiaeueiee noai
e?aiai oeoii/ea, a o eaca?iioieoo?e — ua e ae?aaeaiith aioeieneaeaioiith
ae??th.

Aia?oa i?iaaaeaii ei?aeyoe?eiee aiae?c i?ae iieacieeaie iai?io ?a/iaei
oa no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea o oai?eo ia
OeAe-OEIA. Aeiaaaeaia iayai?noue aca?iica’yce?a i?ae iieacieeaie
nenoiee/ii? ooieoe?? e?aiai oeoii/ea ? iieacieeaie aoaeaaiaeiiai iai?io
oa IIE o oai?eo ia ?COeAe. A o oai?eo ia ?IOeAe-OEIA — i?ae iieacieeaie
no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea ? iieacieeaie
aoaeaaiaeiiai oa e?i?aeiiai iai?i?a.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Aeyaeaii iniaeeaino?
ee?i?/iiai ia?aa?ao OeAe o OEIA. Anoaiiaeaii, ui 10-aeaiiee eo?n
eaca?iioieoo?e ? aioa?ini?aoe?? ni?ey? eiiiainaoe?? OeAe, onoaa? /e
ciaioo? eiai ee?i?/i? i?iyae oa oneeaaeiaiiy, iiceoeaii aieeaa? ia
aoaeaaiaeiee, e?i?aeiee iai?ie, aeoeai?noue IIE oa
no?oeoo?ii-ooieoe?iiaeueiee noai na?oey. ?acoeueoaoe aea/aiiy
iniaeeainoae ee?i?/iiai ia?aa?ao oa e?eoaaiiy oeoe?iaiai ae?aaaoo a
o/aniee?a e?ea?aeaoe?? iane?aee?a *i?iiaeeuenueei? eaoano?ioe
aeei?enoiaothoueny o aeeeaaeaii? ia eaoaae?? a?enueeiai? oa?ai??
Oe?a?inueei? a?enueeiai-iaaee/ii? aeaaeai??, eaoaae?? aiaeie?eiieia??
Iaoe?iiaeueiiai iaaee/iiai oi?aa?neoaoo. Io?eiai? aeai? aeicaieythoue
?aeiiaiaeoaaoe aioa?ini?aoe?th oa eaca?iioieoo?o o e?eoaaeueio i?aeoeeo
aei oe?ieiai aeei?enoaiiy a eiiieaeni?e oa?ai?? oai?eo ia ae?aaao. Oe?
iaoiaee e?eoaaiiy iiaeooue aeei?enoiaoaaoenue a e?eoaaeueieo caeeaaeao
IIC oa II Oe?a?ie.

Iniaenoee aianie aaoi?a. A?i naiino?eii aeeiiaa on? ee?i?/i? oa
eaai?aoi?ii-?ino?oiaioaeuei? aeine?aeaeaiiy, i?ia?a aiae?c, ioi?iea
iaoa??aee aeena?oaoe?? noi?nii c iaoeiaei ea??aieeii. Aaoi?o
iaeaaeeoue aieiaia ?ieue o i?aeaioiaoe? io?eiaieo aeaieo aei an?o
iaoeiaeo ioae?eaoe?e.

Ai?iaaoe?y ?iaioe. ?acoeueoaoe ?iaioe aeiiia?aeaeenue ia Ee?anuee?e
i?nueeee iaoeiai-i?aeoe/i?e eiioa?aioe?? e?ea??a-aiaeie?eiieia?a (1996
??e), can?aeaiiyo eaoaae?e aiaeie?eiieia?? Iaoe?iiaeueiiai iaaee/iiai
oi?aa?neoaoo ? eaoaae?e a?enueeiai? oa?ai?? Oe?a?inueei?
a?enueeiai-iaaee/ii? aeaaeai?? (Ee?a, 1996, 1997), YI Eiia?an? Na?oiai?
Oaaea?aoe?? Oe?a?inueeeo e?ea?nueeeo oiaa?enoa (Iaeana, 1996),
eiioa?aioe?? iieiaeeo o/aieo Iaoe?iiaeueiiai iaaee/iiai oi?aa?neoaoo
(Ee?a, 1997), can?aeaii? Ee?anueeiai i?nueeiai oiaa?enoaa oa?aiaao?a
(1998 ??e).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii /ioe?e iaoeia?
i?aoe?, c yeeo o?e noaoo? a iaoeiaeo oaoiaeo aeo?iaeao, ui caoaa?aeaeai?
AAE Oe?a?ie, oa iaei? oace.

Ia’?i ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 176 noi??ieao
iaoeiiieniiai oaenoo ? neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, 4
?icae?e?a aeanieo aeine?aeaeaiue, iaaiai?aiiy, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e, iieaae/eea e?oa?aoo?e. Oaeno aeena?oaoe?? ?ethno?iaaii 3
iaethieaie, 22 oaaeeoeyie, 1 noaiith. A?ae?ia?ao?/iee iieaae/ee aeeth/a?
349 e?oa?aoo?ieo aeaea?ae.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy. Ianoaaeaii 103 OEIA, ye? i?eeiaee
o/anoue o e?ea?aeaoe?? iane?aee?a *i?iiaeeuenueei? eaoano?ioe a ia??iae
aei eeiiy 1986 ?ieo, ? i?ney oeueiai caoai??ee ia OeAe. Na?aae ieo aoei
28 oai?eo ia ?COeAe ? 75 oai?eo ia ?IOeAe. Eiio?ieueio a?oio neeaee 64
iniae, ye? ia i?eeiaee o/ano? o e?ea?aeaoe?? iane?aee?a aaa??? ia *AAN,
ia i?iaeeaaee ia caa?oaeiaieo ?aae?iioee?aeaie oa?eoi??yo ? caoai??ee ia
OeAe i?ney eeiiy 1986 ?ieo. Na?aae ieo aoei 33 oai?eo ia ?COeAe ? 31
oai?ee ia ?IOeAe. An? ianoaaeai? aoee /ieia?/i? noao?. Ca a?eii,
o?eaae?noth oa aaaee?noth ia?aa?ao ?COeAe oa ?IOeAe a?oie, ui
ii??aithaaeenue, aoee noaoenoe/ii iaeii??aei? (?>0,05).

A iiaeaeueoiio oai?? ia OeAe-OEIA aoee ?iciiae?eai? ia o?e a?oie, ye?
ca a?eii, o?eaae?noth oa aaaee?noth ia?aa?ao caoai?thaaiiy aoee oaeiae
noaoenoe/ii iaeii??aei? (?>0,05). Ia?oa a?oia oai?eo (n=31) e?eoaaeanue
o?aaeeoe?eiith i?ioeae?aaaoe/iith oa?ai??th (7 oai?eo ia ?COeAe oa 24
oai?eo ia ?IOeAe). Oai?? ae?oai? a?oie (n=38) ii?o/ c o?aaeeoe?eiith
oeoe?icieaeoth/ith oa?ai??th io?eioaaee aioa?ini?aaio «Aoaeani?a»,
na?aae ieo oai?eo ia ?COeAe aoei 10 in?a, oai?eo ia ?IOeAe — 28 /ieia?e.
O?aoy a?oia (n=34) aeiaeaoeiai aei o?aaeeoe?eii? oa?ai?? e?eoaaeanue
eaca?iioieoo?ith (11 oai?eo ia ?COeAe oa 23 oai?? ia ?IOeAe).
O?aaeeoe?eia oa?ai?y OeAe aeeth/aea oeoe?icieaeoth/? (?inoe?i aai
ia?i?aeuei? i?aia?aoe — iio?aei? noeueoai?ena/iaeie), aia?ii?ioaeoi?i?
(i?aia?aoe i?eioeiiai? eeneioe) oa aaiaoii?ioaeoi?i? (ea?n?e,
anaioe?ae?) caniae, a?oai?ii? i?aia?aoe (A1, A6, A12 /a?ac aeaiue).

Ae?oaa a?oia oai?eo ia OeAe-OEIA e?eoaaeanue ii?o/ c o?aaeeoe?eiith
oeoe?icieaeoth/ith oa?ai??th aioa?ini?aaioii «Aoaeani?a». I?aia?ao
i?ecia/aee a ia?a?aao i?ae i?eeiiaie ?aee oa ?ioeo e?e?a (1,5-2 aiaeeie
aei ? i?ney ?aee) ii 0,5 o?e/? ia aeaiue. ?aeiiaiaeoaaee caieaaoe
??aeeiith. Eo?n e?eoaaiiy 10 aei?a.

O?aoy a?oia oai?eo ia OeAe-OEIA aeiaeaoeiai aei o?aaeeoe?eii?
oeoe?icieaeoth/i? oa?ai?? e?eoaaeanue eaca?iioieoo?ith. A oeueiio
aeine?aeaeaii? ie aeei?enoiaoaaee aae?e-iaiiiaee eaca? /a?aiiiai niaeo?o
c aeiaaeeiith oaee? 632,8 ii. I?iaiaeeee ii?ii?iaiiy oi/ie eeane/ii?
aeoioieoo?e (eaca?iioieoo?a). Ii?ii?iaiiy i?iaiaeeeinue ca aeiiiiiaith
eaca?ii? onoaiiaee EA-75-1. Aeey eaca?iioieoo?e aeei?enoiaoaaee oi/ee
A36, RP6, G14, o oai?eo c ae?aaaoe/ieie aia?i- oa iae?iiao?yie a noaio
e?eoaaiiy aoee aeeth/ai? ua /ioe?e aeoeai? oi/ee: F2, F3 (/a?ac aeaiue),
V40, V57. Naaine i?iaiaeeee eiaeiee aeaiue, aieea ia iaeio oi/eo o?eaaa
30 naeoiae, any i?ioeaaeo?a o?eaaea ia a?eueoa 6 oaeeei. Eo?n
eaca?iioieoo?e aeeth/aa 10 naain?a. U?euei?noue iiooaeiino? eaca?iiai
aei?ii?iaiiy noaiiaeea 1,5 iAo/ni2. Aeuacacia/ai? aeoioieoo?i? oi/ee
aecia/aee iaoiaeii i?iii?oe?eiiai oeoiy.

Ianoaaeoaaee oai?eo aei oa i?ney e?eoaaiiy — i?e aini?oae?caoe?? oa
i?ney caaa?oaiiy eo?no aioa?ini?aoe?? /e eaca?iioieoo?e.

Aeey ioe?iee iniaeeainoae ia?aa?ao OeAe o OEIA oa aoaeoeaiino? e?eoaaiiy
a?aoiaoaaee aeeiai?eo ee?i?/ieo neiioii?a, nooiaiy ae?eai??, caaaeueiiai
a?eea, caaaeueiiai oieanoa?eio (ON) ieacie oa ON e?iii?ioa?i?a aeniei?
aonoeie (EIAA), e?aao?i?io, na/iaeie, a?e??oa?io, aeoeaiino?
o?ainai?iac, ??ai?a ae?eiceeueiaaiiai aaiiaeia?io (IaA1n), o?oeoicai?io
(OA), iaeiiiaiai ae?aeueaeaa?aeo ieacie ? a?eo?ioeeo?a (IAeAI oa IAeAA).
Ioe?ithaaee oaeiae ?aia?ao?/i? iieacieee, ui oa?aeoa?ecothoue noai
noaeei ieaei?o e?ioe?aie, nei?i/oaaeueio caeaoi?noue i?iea?aea — ca
aeaieie aoiea?ae?ia?ao??.

Caaaeueiee ON ieacie, ON EIAA, IAeAI oa IAeAA aecia/aee ai?iaiaaieie
iaoiaeaie [E.Oiaei?ia, 1963; I.N.Aii/a?aiei e niaao., 1985]; OA ieacie
— ca eaei?eiao?e/iei iaoiaeii c aeei?enoaiiyi i?o?ineiueiai oao?acie?th
[L.Cruschelli, 1990]; ??aaiue IaA1n — oaeiae ca eaei?eiao?e/iei iaoiaeii
[E.V.Subramanian et al., 1980].

Ae?aaiic OeAe anoaiiaethaaany ia i?aenoaa? oa?aeoa?ieo nea?a, aiaiiaco
caoai?thaaiiy e aeeooy, aeaieo o?c?eaeueiiai ianoaaeaiiy, ??ai?a
ae?eai??, IaA1n, aetheico???, eaoiio???.

Aaaee?noue ia?aa?ao OeAe ioe?ithaaee caaaeueiii?eeiyoeie e?eoa??yie
[A.N.Aoeiia e niaao., 1983, 1989; I.E.Aaeaaieeei, 1994; I.O.Noa?eiaa e
niaao., 1997]. E??i oiai, a?aoiaoaaee iniaeeaino? ia?aa?ao ae?aaaoo
(eaa?eueiee, noaa?eueiee), iayai?noue oneeaaeiaiue.

Nooiaiue eiiiainaoe?? OeAe ioe?ithaaee ca aeiiiiiaith ee?i?/ieo ?
eaai?aoi?ieo aeaieo. sseui ca aeaieie ae?eai?/iiai i?io?eth eieeaaiiy
ae?eai?? ia ia?aaeuoaaei 7,0 iiieue/e, a na/? aaetheico??y, HbA1c ia
aeua 7%, oi noai ae?aaaoo ioe?ithaaee ye eiiiainiaaiee. Eieeaaiiy
ae?eai?? aei 11 iiieue/e ?icoe?ithaaee ye noaeiiiainiaaia, a aeua 11
iiieue/e — ye aeaeiiiainiaaia.

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy. Io?eiai? iaie aeai?
na?ae/aoue i?i iayai?noue iaaieo iniaeeainoae ee?i?/iiai ia?aa?ao OeAe o
OEIA. O OEIA, oai?eo ia ?COeAe /ano?oa, i?ae o oai?eo eiio?ieueii?
a?oie, a?aei?/aeanue eaa?euei?noue ia?aa?ao caoai?thaaiiy c?
noeeuei?noth aei a?iiae?eai?e (o 1,8 ?ace, ?<0,05). O oai?eo ia ?IOeAe-OEIA /ano?oa, i?ae o oai?eo aac /i?iiaeeuenueeiai /eiieea a aiaiiac?, a?aei?/aany noai aeaeiiiainaoe?? ae?aaaoo (o 1,5 ?ace, ?<0,05), /ano?oa aeieeaea aoi?eiia noeueoai?eai?aeia ?acenoaioi?noue (o 2,2 ?ace, ?<0,05) oa niinoa??aaeanue eaa?euei?noue ia?aa?ao caoai?thaaiiy c? noeeuei?noth aei a?iiae?eai?e (o 2,6 ?ace, ?<0,05) ? eaoiaoeeaeico (o 3,1 ?ace, ?<0,05). Ca aaaee?noth ia?aa?ao ?COeAe oa ?IOeAe a?oie, ui ii??aithaaeenue, aoee noaoenoe/ii iaeii??aei? (P>0,05).

O oai?eo ia ?COeAe oa ?IOeAe — OEIA /ano?oa, i?ae o oai?eo eiio?ieueii?
a?oie, a?aei?/aeenue: ae?aaaoe/ia iae?iaia?iiao?y ieaei?o e?ioe?aie
(a?aeiia?aeii o 2,6 oa 1,7 ?ace, ?<0,05), ?ON (a?aeiia?aeii o 2,8 oa 1,5 ?ace, ?<0,05), a?oa??aeueia a?ia?oaic?y (a?aeiia?aeii o 3,0 oa 1,8 ?ace, ?<0,05), ae?aaaoe/ia ia?eoa?e/ia iie?iae?iiao?y (a?aeiia?aeii o 2,0 oa 1,8 ?ace, ?<0,01-0,05), ae?aaaoe/ia aioeaoaeiiao?y (a?aeiia?aeii o 3,5 oa 1,9 ?ace, ?<0,05). E??i oeueiai o oai?eo ia ?COeAe-OEIA /ano?oa niinoa??aaeanue ae?aaaoe/ia aaaaoaoeaia iae?iiao?y na?oey (o 4,1 ?ace, ?<0,05), a o oai?eo ia ?IOeAe-OEIA - ae?aaaoe/ia o?aaeaiiy i?e?inoaeei n?oe?aee (o 1,9 ?ace, ?<0,05) oa ae?aaaoe/ia aioa?iiao?y (o 2,6 ?ace, ?<0,05). Ae?aaaoe/ia iao?iiao?y oi/a e ia aeieeaea /ano?oa o OEIA, oai?eo ia ?COeAe, aea oa?aeoa?ecoaaeanue a?eueo i?ia?anoth/ei ia?aa?aii, ui i?aeoaa?aeaeoaaeinue /ano?oei ?icaeoeii iao?ioe/ii? noaae?? inoaiiuei? (o 4,1 ?ace, ?<0,05). O OEIA /anoioa ?ON ca?eueooaaeanue ca ?aooiie aieueiaeo oi?i caoai?thaaiiy, oiaoi noaiiea?ae?? (a a?oi? OEIA 25,3%, a eiio?ieuei?e a?oi? 9,7%, ?<0,05). Ae?aaaoe/ia o?aaeaiiy i?e?inoaeei n?oe?aee o oai?eo ia ?IOeAe-OEIA aeieeaei /ano?oa oa iaei a?eueo i?ia?anoth/ee ia?aa?a, ui i?aeoaa?aeaeoaaeinue /ano?oei ?icaeoeii o ieo i?ie?oa?aoeaii? ?aoeiiiao?? (a a?oi? OEIA 4,0%, a eiio?ieuei?e a?oi? 0%, ?<0,05). Iniaeeaino? ii?ooaiue iai?io ?a/iaei o oai?eo ia ?COeAe oa ?IOeAe - OEIA, a ii??aiyii? c eiio?ieueieie a?oiaie oai?eo ia oe? caoai?thaaiiy, iieyaaee o a?eueo aenieeo ??aiyo ae?eai?? iaoua (o 1,1 ?ace, ?<0,05 a iaio aeiaaeeao) ? OA (o 1,3 oa 1,5 ?ace a?aeiia?aeii, ?<0,05). I?e oeueiio o oai?eo ia ?COeAe-OEIA iaee i?noea iciaee i?aeaeuaiiy aeoeaiino? i?ioean?a IIE a ??aeeiieo na?aaeiaeuao oa iaia?aiieo no?oeoo?ao i?aai?cio (i?aeaeuaiiy IAeAI o 1,3 ?ace, ?<0,05 ? IAeAA o 1,1 ?ace, ?<0,05), a o oai?eo ia ?IOeAe-OEIA - i?aeaeuaiiy ??aiy ae?eai?? i?ney oa?/iaiai iaaaioaaeaiiy (o 1,1 ?ace, ?<0,05) oa aoa?iaaiiino? ieacie e?ia? (ca?eueoaiiy o 1,1 ?ace caaaeueiiai ON ieacie, ?<0,05; oa o 1,3 ?ace ?iaeaeno aoa?iaaiiino?, ?<0,01; ciaioaiiy o 1,2 ?ace ON EIAI, ?<0,05). O oai?eo ia OeAe-OEIA a?aei?/aeenue a?eueo cia/i?, i?ae a eiio?ieuei?e a?oi?, ii?ooaiiy nei?i/oaaeueii? caeaoiino? e?aiai oeoii/ea, ye? aoee cia/i?o? o oai?eo ia ?IOeAe. Oae, o oai?eo ia ?COeAe-OEIA niinoa??aaeinue ca?eueoaiiy ia`?io e?aiai oeoii/ea a ae?anoieo (?<0,05) oa ciaioaiiy oaea?iiai ia`?io na?oey o 1,1 ?ace (?<0,01). A o oai?eo ia ?IOeAe-OEIA a?aei?/aeenue ca?eueoaiiy ia?aaeiueicaaei?o ?ici???a e?aiai oeoii/ea a nenoieo oa ae?anoieo (o 1,1 ?ace, ?<0,05 a iaio aeiaaeeao), ia`?i?a e?aiai oeoii/ea a nenoieo oa ae?anoieo (o 1,2 ?ace, ?<0,01 a iaio aeiaaeeao), ciaioaiiy oaea?iiai ia`?io na?oey oa o?aeoe?? aeeeaeo (o 1,1 ?ace, ?<0,01 a iaio aeiaaeeao). Aioa?ini?aoe?y aoaeaaieieiiiei ni?aaioii "Aoaeani?a" iaea cia/iee ee?i?/iee aoaeo, ni?eyea cieeiaiith ee?i?/ieo i?iya?a ae?aaaoo - ni?aae, nooino? o ?io?, iie?o???, iie?aeein??, i?eoo??? oa ?ioeo, eiai oneeaaeiaiue, i?enei?thaaea no?iee eiiiainaoe?? ae?aaaoo ia oii? ciaioaiiy aeic oeoe?icieaeoth/eo cania?a, i?e noeueoai?eai?aei?e ?acenoaioiino? oaeiae iiceoeaii aieeaaea, aeiiiiiaath/e aeayeei oai?ei ciiao iiaa?iooeny aei aaeeaaiiy oaaeaoie. Eaca?iioieoo?a aoaeoeai?oa ciaiooaaea i?iyae ae?aaaoe/ieo aia?i- oa iae?iiao?e: cieaeoaaea a?eue o ieaei?o ? aa?oi?o e?ioe?aeao, cai?i?iiy ?o oa noaeiie aii?eeiaeo i`yc?a. Naiino?eia i?ioeae?aaaoe/ia oa?ai?y ia i?ioyc? 10 aei?a ia ii?iae?ciaoaaea aoaeaaiaeiee iai?i o oai?eo ia ?COeAe oa ?IOeAe - OEIA, ci?ie ??ai?a iieaciee?a aoaeaaiaeiiai iai?io i?e oeueiio aoee ia nooo?a? (P>0,05 o an?o aeiaaeeao). O oai?eo ia ?COeAe-OEIA eiiieaenia
i?ioeae?aaaoe/ia oa?ai?y c aioa?ini?aaioii «Aoaeani?a» cieaeoaaea ??ai?
ae?eai?? iaoua oa i?ney oa?/iaiai iaaaioaaeaiiy (o 1,4 ?ace, ?<0,01 a iaio aeiaaeeao). Eiiieaenia oa?ai?y c eaca?iith aeoioieoo?ith o oeeo oai?eo cieaeoaaea ??aaiue ae?eai?? i?ney oa?/iaiai iaaaioaaeaiiy o 1,2 ?ace (?<0,05). Oeae aea iaoiae e?eoaaiiy oai?eo ia ?IOeAe-OEIA cieaeoaaa ??aaiue ae?eai?? i?ney oa?/iaiai iaaaioaaeaiiy o 1,3 ?ace (P<0,05). I?e eiia?iiaai?e oa?ai?? c ni?aaioii "Aoaeani?a" o oai?eo ia ?IOeAe-OEIA niinoa??aaeinue cieaeaiiy ??ai?a ae?eai?? iaoua o 1,4 ?ace (?<0,01) oa i?ney oa?/iaiai iaaaioaaeaiiy o 1,5 ?ace (?<0,01), OA o 1,4 ?ace (?<0,05). Naiino?eia i?ioeae?aaaoe/ia oa?ai?y o oai?eo ia ?COeAe-OEIA i?ioeneea?ioe/ii? ae?? ia iaea (P>0,05). Eiiieaenia i?ioeae?aaaoe/ia
oa?ai?y c aioa?ini?aoe??th ni?aaioii «Aoaeani?a» o oeeo oai?eo
cieaeoaaea aoa?iaaii? aeanoeaino? ieacie o 3,5 ?ace (P<0,01) ca ?aooiie cieaeaiiy ??aiy caaaeueiiai ON ieacie o 1,5 ?ace (P<0,01). Eiiieaenia oa?ai?y c eaca?iith aeoioieoo?ith o oai?eo ia ?COeAe-OEIA cieaeoaaea aoa?iaaii? aeanoeaino? ieacie o 3,3 ?ace (P<0,01) ca ?aooiie i?aeaeuaiiy ??aiy ON EIAA o 1,6 ?ace (P, 0,05). Naiino?eia i?ioeae?aaaoe/ia oa?ai?y o oai?eo ia ?IOeAe-OEIA ciaiooaaea ?A o 1,3 ?ace (P<0,01), ia iath/e nooo?aiai aieeao uiaei cieaeaiiy ??aiy caaaeueiiai ON ieacie oa i?aeaeuaiiy ??aiy ON EIAI (?>0,05). Eiiieaenia oa?ai?y c ni?aaioii
«Aoaeani?a» o oeeo oai?eo cieaeoaaea ?iaeaen aoa?iaaiiino? (?A) o 1,9
?ace (P<0,01) ca ?aooiie cieaeaiiy ??aiy caaaeueiiai ON ieacie o 1,4 ?ace (P<0,01). Eiiieaenia oa?ai?y c eaca?iith aeoioieoo?ith o ieo cieaeoaaea ?A o 2,5 ?ace (P<0,01) ca ?aooiie i?aeaeuaiiy ??aiy ON EIAI o 1,5 ?ace (P<0,01). Aeanyoeaeaiiee eo?n naiino?eii? i?ioeae?aaaoe/ii? oa?ai?? oa eiiieaenii? oa?ai?? c aoaeaaieieiiiei aioa?ini?aaioii "Aoaeani?a" o oai?eo ia ?COeAe ? ?IOeAe - OEIA aioeieneaeaioiiai aieeao ia iaa. Eiiieaenia oa?ai?y c eaca?iioieoo?ith ca oeae aea /an o oai?eo ia ?COeAe-OEIA ciaiooaaea aeoeai?noue IIE o ??aeeiieo na?aaeiaeuao oa iaia?aiieo no?oeoo?ao i?aai?cio, ui i?aeoaa?aeaeoaaeinue cieaeaiiyi ??ai?a IAeAI o 1,6 ?ace (P<0,05) oa IAeAA o 1,3 ?ace (P<0,01). Eiiieaenia oa?ai?y c eaca?iioieoo?ith o oai?eo ia ?IOeAe-OEIA oaeiae ciaiooaaea aeoeai?noue IIE a ??aeeiieo na?aaeiaeuao oa iaia?aiieo no?oeoo?ao i?aai?cio, ui i?aeoaa?aeaeoaaeinue cieaeaiiyi ??ai?a IAeAI o 1,5 ?ace (P<0,05) oa IAeAA o 1,1 ?ace (P<0,01). A ?acoeueoao? aeine?aeaeaiiy anoaiiaeaii, ui o OEIA, oai?eo ia ?COeAe ?nioaaee ei?aeyoe?ei? ca'ycee na?aaeiuei? neee i?ae iieacieeaie nenoie?/ii? ooieoe?? e?aiai oeoii/ea ? iieacieeaie aoaeaaiaeiiai iai?io oa IIE (r=0,42-0,69). A o oai?eo ia ?IOeAe-OEIA niinoa??aaeenue ei?aeyoe?ei? ca'ycee na?aaeiuei? neee i?ae iieacieeaie no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea ? iieacieeaie aoaeaaiaeiiai oa e?i?aeiiai iai?i?a (r=0,49-0,69). Canoinoaaiiy aioa?ini?aoe?? ni?aaioii "Aoaeani?a" ? eaca?iioieoo?e o eiiieaeniiio e?eoaaii? oai?eo ia OeAe-OEIA aeicaiey? nooo?ai iie?aueoe no?oeoo?ii-ooieoe?iiaeueiee noai e?aiai oeoii/ea i?e ?COeAe oa ?IOeAe. Canoinoaaiiy oeeo iaoiae?a e?eoaaiiy o oai?eo ia ?COeAe-OEIA (oaae. 1) i?ecaiaeeoue ia o?eueee aei ca?eueoaiiy oaea?iiai ia'?io na?oey oa o?aeoe?? aeeeaeo, ye i?e o?aaeeoe?ei?e oa?ai??, a e aei ciaioaiiy e?ioeaai-nenoie?/iiai ?ici??o e?aiai oeoii/ea (o 1,1-1,2 ?ace, ?<0,05), ia'?io e?aiai oeoii/ea a nenoieo (a iaio aeiaaeeao o 1,2 ?ace, ?<0,01), oa ae?anoieo (o 1,1-1,2 ?ace, ?<0,01) i?e ca?eueoaii? oaea?iiai ia'?io na?oey (a iaio aeiaaeeao o 1,2 ?ace, ?<0,01), oa o?aeoe?? aeeeaeo (a iaio aeiaaeeao o 1,2 ?ace, ?<0,01). O oai?eo ia ?IOeAe-OEIA (oaae. 2) canoinoaaiiy eiia?iiaaieo iaoiae?a e?eoaaiiy oaeiae ca?eueoo? oaea?iee ia'?i na?oey (o 1,1-1,2 ?ace, ?<0,01) oa o?aeoe?th aeeeaeo (a iaio aeiaaeeao o 1,2 ?ace, ?<0,01) i?e ciaioaii? e?ioeaai-ae?anoie?/iiai ?ici??o e?aiai oeoii/ea (a iaio aeiaaeeao o 1,1 ?ace, ?<0,05), oa ia'?i?a e?aiai oeoii/ea a nenoieo (o 1,2-1,3 ?ace, ?<0,01) ? ae?anoieo (o 1,1-1,2 ?ace, ?<0,01). Oaaeeoey 1 Aieea aioa?ini?aoe?? ni?aaioii “Aoaeani?a” ? eaca?iioieoo?e ia iieacieee no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea o oai?eo ia ?COeAe-OEIA IieacieeE?eiaai? o?aaeeoe?eii, n=7E?eiaai? o?aaeeoe?eii, n=7E?eiaai? aioa?ini?aoe??th,n=10E?eiaai? aioa?ini?aoe??th,n=10E?eiaai? eaca?iioieoo?ithn=11E?eiaai? eaca?iioieoo?ithn=11Aei ?eoaaiiy I?ney Aei e?eoaaiiy I?neyAei ?eoaaiiy I?neyDs (ni) P Dd (ni) P Vs (eoa.ni) P Vd (eoa.ni) P SU (eoa.ni) P EF (%) P 4,08+0,16 5,18+0,32 70,29+2,05 138,93+2,85 68,90+0,95 60,43+1,08 3,91+0,18 >0,05

4,97+0,28

>0,05

66,69+1,05

>0,05

134,07+2,11

>0,05

81,99+1,11

<0,01 64,57+0,77 <0,05 4,10+0,16 5,28+0,25 71,50+2,01 140,69+2,18 70,03+1,18 59,30+0,82 3,59+0,15 <0,05 4,93+0,21 >0,05

61,12+1,03

<0,01 124,04+2,22 <0,01 82,15+0,79 <0,01 68,10+0,72 <0,01 4,06+0,17 5,30+0,23 72,20+1,91 143,65+2,02 69,77+1,13 58,82+0,95 3,54+0,18 <0,05 4,85+0,20 >0,05

58,79+0,99

<0,01 118,28+1,73 <0,01 84,65+0,78 <0,01 72,36+0,86 <0,01I?ei?oea: ? - aeinoia??i?noue ??cieoeue aei ? i?ney e?eoaaiiy; Ds - ia?aaeiueicaaei?e ?ici?? e?aiai oeoii/ea a nenoieo; Dd - ia?aaeiueicaaei?e ?ici?? e?aiai oeoii/ea a ae?anoieo; Vs - ia'?i e?aiai oeoii/ea a nenoieo; Vd - ia'?i e?aiai oeoii/ea a ae?anoieo; SU - oaea?iee ia'?i na?oey; EF - o?aeoe?y aeeeaeo. Oaaeeoey 2 Aieea aioa?ini?aoe?? ni?aaioii “Aoaeani?a” ? eaca?iioieoo?e ia iieacieee no?oeoo?ii-ooieoe?iiaeueiiai noaio e?aiai oeoii/ea o oai?eo ia ?IOeAe-OEIA IieacieeE?eiaai? o?aaeeoe?eii, n=24E?eiaai? o?aaeeoe?eii, n=24E?eiaai? aioa?ini?aoe??th,n=28E?eiaai? aioa?ini?aoe??th,n=28E?eiaai? eaca?iioieoo?ithn=23E?eiaai? eaca?iioieoo?ithn=23Aei ?eoaaiiy I?ney Aei e?eoaaiiy I?neyAei ?eoaaiiy I?neyDs (ni) P Dd (ni) P Vs (eoa.ni) P Vd (eoa.ni) P SU (eoa.ni) P EF (%) P 4,59+0,18 5,68+0,17 86,65+2,31 160,56+3,73 63,40+1,22 43,75+0,99 4,54+0,17 >0,05

5,49+0,15

>0,05

79,22+2,03

<0,05 156,40+3,05 >0,05

72,99+0,72

<0,01 47,39+1,07 <0,05 4,69+0,17 5,73+0,16 87,49+3,49 162,66+4,24 64,55+1,16 44,39+1,07 4,52+0,14 >0,05

5,30+0,14

<0,05 71,21+1,74 <0,01 142,61+2,85 <0,01 73,59+0,87 <0,01 51,92+0,80 <0,01 4,57+0,19 5,67+0,19 85,11+2,97 158,96+3,67 61,53+1,32 42,52+0,76 4,35+0,16 >0,05

5,15+0,15

<0,05 66,27+2,74 <0,01 135,67+2,38 <0,01 75,13+0,71 <0,01 52,61+0,43 <0,01I?ei?oea: ? - aeinoia??i?noue ??cieoeue aei ? i?ney e?eoaaiiy; Ds - ia?aaeiueicaaei?e ?ici?? e?aiai oeoii/ea a nenoieo; Dd - ia?aaeiueicaaei?e ?ici?? e?aiai oeoii/ea a ae?anoieo; Vs - ia'?i e?aiai oeoii/ea a nenoieo; Vd - ia'?i e?aiai oeoii/ea a ae?anoieo; SU - oaea?iee ia'?i na?oey; EF - o?aeoe?y aeeeaeo. 12 Iane?aeee *i?iiaeeuenueei? aaa??? ne?ae ?icaeyaeaoe ye eiiieaen ?aae?aoe?eieo ? ia?aae?aoe?eieo /eiiee?a. Inoaii?e neeaaea?oueny c? cia/ieo o?ce/ieo oa aiioe?eieo iaaaioaaeaiue, ci?i niiniao aeeooy ? oa?/oaaiiy, "?aae?aoe?eiiai iai?oaeaiiy" [I.I.Etha/aiei e niaao., 1991; A.I.Na?aaethe, 1997]. ?aae?aoe?eiee /eiiee iiaea aooe iaea?eueo ?iia??iith i?e/eiith ?COeAe oa ?IOeAe. ?aae?aoe?y aaciina?aaeiuei iioeiaeaeo? aaoa-ee?oeie ino??aoe?a i?aeoeoieiai? caeice [C.E.A?eeaaneay, 1993]. Ii?yae c iioeiaeaeaiiyi iieaeoe AeIE [A.Maccubbin et al., 1991] a?aei?/athoueny ci?ie a no?oeoo?? ee?oeiieo iaia?ai aiane?aeie aeoeaaoe?? IIE [E.O.Yeaeon, 1994, 1996; N.I.ss?iiiaiei, 1997; S.P.Verma et al., 1991]. A aenia?eiaioaeueieo ? ee?i?/ieo aeine?aeaeaiiyo anoaiiaeaii, ui a oiiaao i?aeaeuaii? ooieoe?iiaeueii? aeoeaiino?, coiiaeaii? aieeaii eiiieaeno ia?aae?aoe?eieo /eiiee?a aaa??? ia *AAN, ?aae?i?acenoaioi?noue aiaeie?eiieo i?aai?a cia/ii cieaeo?oueny [A.E.Aeaaeia, 1982]. Aeieeiaiiy ?IOeAe o OEIA "eiaeiiai ia??iaeo" iiaea aooe iia`ycaii c iayai?noth o a?eueoino? c ieo iaee??iiy, a?iiooieoe?? ueoiaeaeii? caeice, ciaioaiiyi /ooeeaino? ?aoeaioi??a aee?iai? oeaieie aei ?inoe?io. Ia aeeeth/aia eiio??inoey?ia ae?y AEOA ? ei?oeeinoa?i?ae?a, ??aaiue yeeo o in?a c ?iei?ii?iaaiei ?aae?iaeoeaiei eiaeii i?aeaeuaiee [O.I.Aacaa?oa c? ni?aaao., 1996]. Aeine?aeaeaiiy ooieoe?? a?iioaeaii-a?iio?ca?ii-iaaeie?ieeiai? nenoaie o in?a c ?iei?ii?iaaiei ?aae?iaeoeaiei eiaeii aeyaeee a ieaci? e?ia? aenie? ??ai? ei?oecieo, ei?oeeio?ii?io, niiaoio?ii?io, ye? ? ai?iiiaie a?ia?ae?eai?coth/i? ae?? [O.I.Aacaa?oa c? ni?aaao., 1996; I.I.Eiaaeaiei, 1996]. A ao?iiaoiaaiac? ?COeAe /?eueia i?noea caeiathoue ?ioaeoe?? oa ?ioii? c?ooaiiy a i?aai?ci?. O OEIA a?aei?/a?oueny cieaeaiiy ?ioiiiai noaoono i?aai?cio c ?icaeoeii aoi?eiiiai ?ioiiaeao?oeeoo [Ae.?.Caaieioiee, 1996], ui ni?ey? i?aeaeuaiith caoai?thaaiino? ia a??oni? oai?iae, o?ii?caoe?? ? ?aoeeaeeaoth/iio ia?aa?ao caiaeueieo i?ioean?a, ye? iiaeooue aooe ?iia??ieie i?e/eiaie ?COeAe [A.?.Aioeth?ei, 1995]. Ca?aeii c io?eiaieie a oiae? aeine?aeaeaiiy aeaieie oa aeaieie e?oa?aoo?ieo aeaea?ae ie neeaee noaio ?icaeoeo OeAe a OEIA "eiaeiiai ia??iaeo" (noaia 1). Noaia Noaia ?icaeoeo oeoe?iaiai ae?aaaoo a o/aniee?a e?ea?aeaoe?? iane?aee?a aaa??? ia *i?iiaeeuenuee?e AAN “eiaeiiai ia??iaeo” *i?iiaeeuenueeee /eiiee 14 AENIIAEE 1. Ia?aa?a ?COeAe o OEIA a?eueo eaa?eueiee, i?ae a eiio?ieuei?e a?oi?, c? noeeuei?noth aei a?iiae?eai?e. A?i oa?aeoa?eco?oueny /ano?oei ?icaeoeii iae?iaia?iiao?? ieaei?o e?ioe?aie, ?ON, a?oa??aeueii? a?ia?oaic??, ia?eoa?e/ii? iie?iae?iiao??, aioeaoaeiiao??, aaaaoaoeaii? iae?iiao?? na?oey, oa a?eueo i?ia?anoth/ei ia?aa?aii iao?iiao??. 2. Ia?aa?a ?IOeAe o OEIA oa?aeoa?eco?oueny a?eueo eaa?eueiei, i?ae a eiio?ieuei?e a?oi?, ia?aa?aii oai?iae c? noeeuei?noth aei a?iiae?eai?e oa eaoiaoeeaeico, /ano?oei ?icaeoeii aeaeiiiainaoe??, aoi?eiii? noeueoai?eai?aeii? ?acenoaioiino?, iae?iaia?iiao?? ieaei?o e?ioe?aie, ?ON, a?oa??aeueii? a?ia?oaic??, ia?eoa?e/ii? iie?iae?iiao??, aioeaoaeiiao??, aioa?iiao??, o?aaeaiiy i?e?inoaeei n?oe?aee oa a?eueo i?ia?anoth/ei eiai ia?aa?aii. 3. O oai?eo ia ?COeAe-OEIA niinoa??aa?oueny i?aeaeuaiiy ??ai?a ae?eai?? iaoua ? o?oeoicai?io, i?aeaeuaiiy aeoeaiino? IIE o ??aeeiieo na?aaeiaeuao e iaia?aiieo no?oeoo?ao i?aai?cio. O oai?eo ia ?IOeAe-OEIA niinoa??aa?oueny i?aeaeuaiiy ??ai?a ae?eai?? iaoua oa i?ney oa?/iaiai iaaaioaaeaiiy, o?oeoicai?io, caaaeueiiai oieanoa?eio ieacie, ?iaeaeno aoa?iaaiiino?, oa ciaioaiiy oieanoa?eio EIAA. 4. Nei?ioeeaa caeaoi?noue i?iea?aea o OEIA, oai?eo ia OeAe, ia? iaai? iniaeeaino?. O oai?eo ia ?COeAe a?aei?/a?oueny ca?eueoaiiy, a ii??aiyii? c eiio?ieueiith a?oiith, ia'?io e?aiai oeoii/ea a ae?anoieo oa ciaioaiiy oaea?iiai ia'?io na?oey. O oai?eo ia ?IOeAe-OEIA a?aei?/a?oueny ca?eueoaiiy ia'?i?a oa ?ici???a e?aiai oeoii/ea a nenoieo ? ae?anoieo, ciaioaiiy oaea?iiai ia'?io na?oey oa o?aeoe?? aeeeaeo. Nei?ioeeaa caeaoi?noue i?iea?aea ciaoiaeeoueny a ei?aeyoe?ei?e caeaaeiino? na?aaeiuei? neee a?ae noaio aoaeaaiaeiiai iai?io oa aeoeaiino? IIE o oai?eo ia ?COeAe-OEIA, ? a?ae noaio aoaeaaiaeiiai oa e?i?aeiiai iai?i?a o oai?eo ia ?IOeAe-OEIA. 5. I?ioeae?aaaoe/ia oa?ai?y c canoinoaaiiyi aioa?ini?aaioo "Aoaeani?a" ni?ey? cieeiaiith i?iya?a ae?aaaoo oa eiai oneeaaeiaiue, i?enei?th? oa?i?i eiiiainaoe?? ia oii? ciaioaiiy aeic oeoe?icieaeoth/eo cania?a, i?e aoi?eii?e noeueoai?eai?aei?e ?acenoaioiino? ni?ey? a?aeiiaeaiith i?eeiio ia?i?aeueieo oeoe?icieaeoth/eo cania?a. Eiiieaenia oa?ai?y c eaca?iith aeoioieoo?ith ae?aci?oa aieeaa? ia i?iyae ae?aaaoe/ieo aia?i- oa iae?iiao?e. 6. Oa?ai?y ae?aaaoo c aioa?ini?aaioii "Aoaeani?a" ae??aith? iieacieee aoaeaaiaeiiai ? e?i?aeiiai iai?i?a o oai?eo ia OeAe-OEIA, ui i?aeoaa?aeaeo?oueny cieaeaiiyi ??ai?a ae?eai?? iaoua oa i?ney oa?/iaiai iaaaioaaeaiiy, o?oeoicai?io, caaaeueiiai oieanoa?eio ieacie, ?iaeaeno aoa?iaaiiino?. Oeae iaoiae e?eoaaiiy i?ecaiaeeoue aei iie?auaiiy nei?ioeeai? caeaoiino? na?oey, ui i?aeoaa?aeaeo?oueny ciaioaiiyi ?ici???a e?aiai oeoii/ea a nenoieo o oai?eo ia ?COeAe oa ae?anoieo o oai?eo ia ?IOeAe, ia'?i?a e?aiai oeoii/ea a nenoieo ? ae?anoieo, ca?eueoaiiyi oaea?iiai ia'?io na?oey ? o?aeoe?? aeeeaeo o oai?eo ia ?COeAe oa ?IOeAe. 7. Eiiieaenia oa?ai?y c eaca?iith aeoioieoo?ith o oai?eo ia OeAe-OEIA ae??aith? iieacieee e?i?aeiiai iai?io, IIE, ui i?aeoaa?aeaeo?oueny ca?eueoaiiyi ??aiy oieanoa?eio EIAA, cieaeaiiyi ?iaeaeno aoa?iaaiiino?, iaeiiiaiai ae?aeueaeaa?aeo ieacie oa a?eo?ioeeo?a. Oeae iaoiae e?eoaaiiy ni?ey? ciaioaiith ?ici???a e?aiai oeoii/ea a nenoieo o oai?eo ia ?COeAe oa ae?anoieo o oai?eo ia ?IOeAe, ia'?i?a e?aiai oeoii/ea a nenoieo ? ae?anoieo, i?aeaeuaiith oaea?iiai ia'io na?oey, o?aeoe?? aeeeaeo o oai?eo ia ?COeAe oa ?IOeAe. I?AEOE*I? ?AEIIAIAeAOe?? 1. A eiiieaeniiio e?eoaaii? oai?eo ia OeAe-OEIA, a yeeo ia?aaaaeathoue iciaee ii?ooaiue aoaeaaiaeiiai ? e?i?aeiiai iai?io ca ?aooiie i?aeaeuaiiy ??aiy caaaeueiiai oieanoa?eio ieacie aeey i?enei?aiiy ii?iae?caoe?? aoaeaaiaeiiai iai?io, onoiaiiy ae?ne?iii?ioa?iai??, i?enei?aiiy no?ie?a eiiiainaoe?? ae?aaaoo oa i?aeaeuaiiy nei?ioeeai? caeaoiino? na?oey ?aeiiaiaeo?oueny i?ecia/aoe aoaea?iaeiee aieieiiiee aioa?ini?aaio "Aoaeani?a" ii 0,5 o?e ?ace ia aeaiue a ia?a?aao i?ae i?eeiiaie ?ae? oa ?io?o e?e?a ia i?ioyc? 10 aei?a. 2. O cacia/aii? eaoaai??? oai?eo, a yeeo ia?aaaaeathoue iciaee ii?ooaiiy e?i?aeiiai iai?io ca ?aooiie cieaeaiiy ??aiy oieanoa?eio EIAA oa i?aeaeuaiiy aeoeaiino? IIE c iaoith onoiaiiy ae?ne?iii?ioa?iai??, i?eai?/aiiy IIE oa iie?auaiiy nei?ioeeai? caeaoiino? i?iea?aea aeioe?eueii canoiniaoaaoe eaca?io aeoioieoo?o iecueeiaia?aaoe/iei aae?e-iaiiiaei eaca?iei aei?ii?iaiiyi c aeiaaeeiith oaee? 632,8 ii, u?euei?noth iiooaeiino? 1,5 iAo/ni2. Iaea?eueo aoaeoeaiei ? i?ecia/aiiy 10 naain?a eaca?iioieoo?e i?e o?eaaeino? iaeiiai naaino ia a?eueoa 6 oaeeei. IA?AE?E IOAE?EAOe?E II OAI? AeENA?OAOe?? 1. Aioa?ini?aaio "Aoaeani?a" o eiiieaeniiio e?eoaaii? oai?eo ia oeoe?iaee ae?aaao // E?ee. - 1996.- N 5-6.- N. 64-68. 2. Iniaeeaino? ee?i?/iiai ia?aa?ao oeoe?iaiai ae?aaaoo a o/aniee?a e?ea?aeaoe?? iane?aee?a aaa??? ia *i?iiaeeuenuee?e AAN // AEo?iae AII Oe?a?ie. - 1997.- O. 3, N 4. N. 681-688 (ni?aaao. I.I.Aiaeia?). 3. I?e?iaei? ceaeia? ? aoaeaoeaa? aieieiii? aioa?ini?aaioe a eiiieaeni?e oa?ai?? oeoe?iaiai ae?aaaoo // Oa?i. aeo?iae. - 1997.- N 3.- N. 67-69 (ni?aaao. ?.A?euenueea). 4. Eaca?iioieoo?a a e?eoaaii? oai?eo ia oeoe?iaee ae?aaao, ye? caciaee aieeao iane?aee?a aaa??? ia *i?iiaeeuenuee?e AAN // YI Eiia?an NOOEO (9-14 aa?aniy 1996 ?.): Oace aeii. - Iaeana, 1996.- N. 91-92 (ni?aaao. I.I.Aiaeia?, I.I.I?enooithe). AIIOAOe?ss Ai?iiei A.A. Iniaeeaino? ee?i?/iiai ia?aa?ao oa e?eoaaiiy oeoe?iaiai ae?aaaoo a o/aniee?a e?ea?aeaoe?? iane?aee?a aaa??? ia *i?iiaeeuenuee?e AAN. ?oeiien aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.14 - aiaeie?eiieia?y. ?inoeooo aiaeie?eiieia?? oa iai?io ?a/iaei ?iai? A.I.Eii?na?aiea AII Oe?a?ie, Ee?a, 1998. A OEIA, oai?eo ia ?inoe?iicaeaaeiee oeoe?iaee ae?aaao (?COeAe), /ano?oa, i?ae o oai?eo eiio?ieueii? a?oie, ?icaeaathoueny iae?iaia?iiao??, iae?iiao??, a?oa??aeueia a?ia?oaic?y, a a OEIA, oai?eo ia ?inoe?iiiacaeaaeiee oeoe?iaee ae?aaao (?IOeAe), aei oeueiai i?e?aeio?oueny ? /ano?oee ?icaeoie i?e?iaia?iiao?e oa aoi?eiii? noeueoai?eai?aeii? ?acenoaioiino?, a oaeiae cia/i?o? ii?ooaiiy nei?ioeeai? caeioiino? i?iea?aea. Eiiieaenia oa?ai?y OeAe c aioa?ini?aaioii "Aoaeani?a" oa eaca?iioieoo?ith ni?ey? i?enei?aiith aeinyaiaiiy eiiiainaoe??, iie?auaiith ia?aa?ao, cieaeaiith ee?i?/ieo i?iya?a ae?aaaoo, iie?auo? iieacieee aoaeaaiaeiiai oa e?i?aeiiai iai?i?a, no?oeoo?ii-ooieoe?iiaeueiee noai e?aiai oeoii/ea, ia? ae?aaeaiee aioeieneaeaioiee aoaeo o oai?eo ia OeAe-OEIA. Eeth/ia? neiaa: oeoe?iaee ae?aaao, aaa??y ia *i?iiaeeuenuee?e AAN, ae?eiceeueiaaiee aaiiaeia?i, o?oeoicai?i, oieanoa?ei, iaeiiiaee ae?aeueaeaa?ae, nei?ioeeaa caeaoi?noue i?iea?aea, eaca?ia aeoioieoo?a, aioa?ini?aoe?y. AIIIOAOeEss Ai?iiei A.A. Iniaaiiinoe eeeie/aneiai oa/aiey e ea/aiey naoa?iiai aeeaaaoa o o/anoieeia eeeaeaeaoeee iineaaenoaee aaa?ee ia *a?iiaueueneie AYN. ?oeiienue aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.14 - yiaeie?eiieiaey. Einoeooo yiaeie?eiieiaee e iaiaia aauanoa eiaie A.I.Eiienna?aiei AII Oe?aeiu, Eeaa, 1998. O OEIA, aieueiuo einoeeicaaeneiui naoa?iui aeeaaaoii (ECNAe), /aua, iaaeaee a eiio?ieueiie a?oiia aieueiuo, ?acaeaathony iae?iaiaeiiaoee, iae?iiaoee, a?oa?eaeueiay aeia?oaicey, a o OEIA, aieueiuo einoeeiiiacaaeneiui naoa?iui aeeaaaoii (EINAe), e yoiio i?eniaaeeiythony e aieaa /anoia ?acaeoea iee?iaiaeiiaoee e aoi?e/iie noeueoaieeaieaeiie ?acenoaioiinoe. O yoeo aieueiuo ioia/athony oaeaea cia/eoaeueiua ia?ooaiey nie?aoeoaeueiie niiniaiinoe na?aeoea, eioi?ua aieaa au?aaeaiu i?e EINAe. Eiiieaeniay oa?aiey NAe n yioa?ini?aaioii "Aoaeani?a" e eaca?iioieoo?ie niinianoaoao onei?aieth aeinoeaeaiey eiiiainaoeee, oeo/oaieth oa/aiey, nieaeaieth eeeie/aneeo i?iyaeaiee aeeaaaoa, oeo/oaao iieacaoaee oaeaaiaeiiai e eeieaeiiai iaiaiia, no?oeoo?ii-ooieoeeiiaeueiia ninoiyiea eaaiai aeaeoaei/ea, eiaao au?aaeaiiue aioeieneaeaioiue yooaeo o aieueiuo NAe-OEIA. Eeth/aaua neiaa: naoa?iue aeeaaao, aaa?ey ia *a?iiaueueneie AYN, aeeeiceee?iaaiiue aaiiaeiaei, o?oeoicaiei, oieanoa?ei, iaeiiiaue aeeaeueaeaaeae, nie?aoeoaeueiay niiniaiinoue ieiea?aea, eaca?iay aeoioieoo?a, yioa?ini?aoeey. SUMMARY Voronko A.A. Special features of clinical course and treatment of diabetes mellitus in patients with diabetes mellitus who took part in the elimination of the consequences of Chernobyl accident. The Dissertation Thesis submitted for the Scientific Degree of Ph. D. (Medicine) in the Speciality 14.01.14 - Endocrinology. The Institute of Endocrinology and Metabolism named after V.P.Komissarenko (AMS, Ukraine), Kyiv, 1998. The investigation revealed the higher occurrence of macroangiopathies, neuropathies, arterial hypertension in liquidators with insulin-dependent diabetes. In liguidators with insulin-independent diabetes, the above pathologies were microangiopathies and secondary sulphanylamide resistance. Also, these patients displayed significant disturbances of cardic contractility, which were more pronounced in patients with insulin-independent diabetes. The enterosorbtion and laseropuncture shows positive clinical effect, promotes diabetes compensation in combination with hypoglycemic drugs. The results show neuro- and angioprotective properties of enterosorbtion and laseropuncture. The treatment with enterosorbtion and laseropuncture improves lipid and carbohydrate metabolism, peroxide oxidation of lipids, and heart constriction. Key words: diabetes mellitus, accident in the Chernobyl atomic power-station, glycosilated haemoglobin, fructosamine, cholesterol, malonov dialdegide, heart constriction, laseropuncture, enterosorbtion.

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