?INOEOOO OOEC?AO??? ? IOEUeIIIIEIA?? ?i. O.A.ssIIANUeEIAI

AEAAeAI?? IAAeE*IEO IAOE OE?A?IE

Nooaiiaa E?ae?y Aiaoie??aia

OAeE: 616.002.5-053.5/.6 : 616-036.1-07-08

INIAEEAINO? ?IO?EUeO?AOEAIIAI OOAA?EOEUeICO EAAAI?A O I?AeE?OE?A CA
NO*ANIEO OIIA

14.01.26 — ooec?ao??y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioo aeeiiaii a Oa?e?anueeiio ?inoeooo? oaeineiiaeaiiy e?ea??a IIC
Oe?a?ie.

(?aeoi? — aeieoi? iaaee/ieo iaoe, i?ioani? I.?.Oaenthe).

IAOEIAEE EA??AIEE:

aeieoi? iaaee/ieo iaoe, i?ioani? Aaea??e Naiaiiae/ E?ooueei, caa?aeoaa/

eaoaae?e ooec?ao??? ? ioeueiiiieia??, i?i?aeoi? ii iaa/aeuei?e ?iaio?
Oa?e?anueeiai

?inoeoooo oaeineiiaeaiiy e?ea??a IIC Oe?a?ie

IO?Oe?EI? IIIIAIOE:

aeieoi? iaaee/ieo iaoe, i?ioani? Eino?ii?ia A?eoi??y Iaae?aia,
caa?aeoaa/ea

a?aeae?eaiiyi ooec?iiaae?ao??? ?inoeoooo ooec?ao??? ? ioeueiiiieia??
?i. O.A.ssiianueeiai

AII Oe?a?ie, Ee?a

aeieoi? iaaee/ieo iaoe, i?ioani? ?eueieoeueeee ?aai A?eai?iae/,
caa?aeoaa/ eaoaae?e ooec?ao??? oa ioeueiiiieia?? Euea?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo IIC Oe?a?ie.

I?IA?AeIA ONOAIIAA

Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC
Oe?a?ie, eaoaae?a ooec?ao???.

Caoeno a?aeaoaeaoueny «_26__» ea?oiy i 13 aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.552.01 i?e ?inoeooo? ooec?ao??? ?
ioeueiiiieia?? ?i. O. A. ssiianueeiai AII Oe?a?ie (252000, i. Ee?a,
INI-650, oca?c I?ioan?a ss?, 7).

C aeena?oaoe??th iiaeia iciaeiieoeny a a?ae?ioaoe? ?inoeoooo ooec?ao???
? ioeueiiiieia?? ?i. O.A. ssiianueeiai AII Oe?a?ie, i. Ee?a, oca?c
I?ioan?a ss?,7.

Aaoi?aoa?ao ?ic?neaiee » 20 » aa?aciy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee
AE. A. Aaaioeaaa

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. O iao /an o aaaaoueio e?a?iao caiii? eoe?, o oiio
/ene? e aeniei?icaeiaieo, niinoa??aa?oueny c?inoaiiy caoai?thaaiino? ia
ooaa?eoeueic, ui aeicaiey? aiai?eoe i?i ia?ao?ae aiaeai?? aei ai?aeai??
ooaa?eoeueico [TH. ?. Oauaiei, 1995; TH. ?. Oauaiei ? ni?aaao., 1996; I.
A. Oiiaiei, 1995, 1997; A. Bajan, 1988; Ae. E?iooii ? ni?aaao., 1996].
Ia i?aenoaa? oeueiai AIIC o ea?oi? 1993 ?ieo iaieineea ooaa?eoeueic
aeiaaeueiith i?iaeaiith.

Caei?ia’y ae?oae ? i?aee?oe?a ? a?aeoai?aiiyi ? iane?aeeii
nioe?aeueii-aeiiii?/ieo, aeieia?/ieo ? iaaee/ieo i?iaeai aei?ineiai
ianaeaiiy.

Ioi?iia caei?ia’y i?ae?inoath/iai iieie?iiy caaaeaee i?eaa?oaea oaaao
iaaee/ii? iaoee, oiio ui oeae eiioeiaaio aecia/a? caei?ia’y iaoe??,
?? o?oaeiaee oa ?ioaeaeooaeueiee iioaioe?ae

[TH. A. Eiyc?a, 1986; A. I. Iaai?ia, 1991; O. I. Neaei?aiei,1993].

Inoaii?ie ?ieaie a Oe?a?i? i?e c?inoaii? caoai?thaaiino? ia ooaa?eoeueic
aei?ineiai ianaeaiiy a?aecia/a?oueny oaiaeaioe?y aei iiieiaeaeoaaiiy
ooaa?eoeueico: c 1990 aei 1994 ?ieo caoai?thaai?noue ia ooaa?eoeueic
ae?oae ? i?aee?oe?a ca?eueoeeany ia 27,9 % [A. I. Eino?ii?ia, 1994; A.
I. Iaeueiee, 1994]. Caoai?thaai?noue i?aee?oe?a caaaeaee aoea o 2 — 4
?ace aeuith, i?ae caoai?thaai?noue ae?oae [A. I. *a?eeiaa ? ni?aaao.,
1989; A. A. ?ai?ia, A. I. I?eiea?a, 1997], iniaeeai aeniea
caoai?thaai?noue i?aee?oe?a c aiaieu ooaa?eoeueicii? ?ioaeoe?? [A. I.
Eino?ii?ia, 1987; I. N. Ianyie?ia, 1993]. Oea iiynith?oueny
nai???aei?noth i?aee?oeiaiai a?eo, iaoiiaeaiith ia?aaoaeiaith iniiaieo
?aaoethth/eo nenoai i?aai?cio, ui i?iyaey?oueny cieaeaiiyi eiai caoenieo
iiaeeeainoae ? niiioea? aaaaeaoe i?aee?oe?a a?oiith ?eceeo ye o
caaaeuei?e iaoieia??, oae ? o ooec?ao??? [A. A. O??niaa ? ni?aaao.,
1985; A. I. Einoth??ia, I. I. Ei?ai?a, 1986; I. N. Ianyie?ia, A. A.
Eooaeiaa, 1996].

Ooaa?eoeueic eaaaiue o i?aee?oe?a ca oiia no/aniino? oa?aeoa?eco?oueny
iayai?noth ?iciaaeo eaaaiaai? oeaieie (35 — 69 %), aaeoa??iaeae?eaiiyi
(31,1 — 86,6 %), a?ia?a?a?/iith /ooeea?noth aei ooaa?eoe?io (18,5 —
43 %), oneeaaeiaiei ia?aa?aii caoai?thaaiiy (11,0 — 37,8 %) [E. I.
Iioaiiaa, 1980; A. I. Aenueiiiaa, 1988; E. A. Aai??a ? ni?aaao., 1989;
?. I. N??aiei, 1992]. Inoaii?ie ?ieaie a?aecia/a?oueny iiaaae/aiiy
no?oeoo?e ee?i?/ieo oi?i ooaa?eoeueico o i?aee?oe?a, ca?eueoaiiy ieoiii?
aaae ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue [A. A. Eo/a? ? ni?aaao.,
1994; A. A. O??niaa, I. N. Ianyie?ia, 1994; I. A. Iaaeiaa, 1995].

Ia ooaa?eoeueicio ?ioaeoe?th ?aaao? aanue i?aai?ci, ia?aa?a ? e?iaoeue
?? cia/iith i??ith aecia/athoueny noaiii ?ioiieia?/ii? ?aaeoeaiino?;
?ioiieia?/ia nenoaia o?nii iiaycaia c aiaeie?eiiith, yea cae?enith?
iiaeoethth/ee aieea ia o?ae ?ioiieia?/ieo ?aaeoe?e oa aecia/a? neeo
?ioiieia?/ii? a?aeiia?ae?. [E. O. *a?iooaiei, E. N. Eiainiaa, 1978; I.
I. Aaa?aao, A. ss. Aa?aa?o, 1980, 1988; E.O. Aa?eaa? ? ni?aaao., 1990;
E. O. *a?iooaiei, 1993].

Ioaea, aeniea caoai?thaai?noue ia ooaa?eoeueic i?aee?oe?a, nioe?aeueia
cia/ou?noue oeueiai a?eiaiai eiioeiaaioo ? eiai o?c?ieia?/i?
iniaeeaino?, iiaaae/aiiy no?oeoo?e ee?i?/ieo oi?i ooaa?eoeueico c?
ca?eueoaiiyi ieoiii? aaae ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue, yeee
oa?aeoa?eco?oueny iaoe?i?noth o?aaeaiiy, noeeuei?noth aei ?iciaaeo ?
aaeoa??iaeae?eaiiy, aecia/athoue aeooaeuei?noue oe??? i?aoe?.

O e?oa?aoo?? ? aeine?aeaeaiiy, ye? i?enay/ai? ?io?eueo?aoeaiiio
ooaa?eoeueico eaaaiue o aei?ineiai ianaeaiiy [I. I. Ia?nanyi, 1972; N.
A. Oaaein??aa, 1992; A. A. Ia?oeeue?a, 1997] ? caiaei i?aoeue uiaei
aea/aiiy oe??? ee?i?/ii? oi?ie o in?a i?aee?oeiaiai a?eo, ui noaei
i?aenoaaith aeey i?iaaaeaiiy oeueiai aeine?aeaeaiiy.

Iaoa ?iaioe — aea/eoe iniaeeaino? ?io?eueo?aoeaiiai ooaa?eoeueico
eaaaiue o i?aee?oe?a ca no/anieo oiia c o?aooaaiiyi noaio ?ioiieia?/ii?
?aaeoeaiino? oa ai?iiiaeueiiai i?io?eth aeey oaeineiiaeaiiy aeyaeaiiy,
ae?aaiinoeee, e?eoaaeueii? oaeoeee ? iie?auaiiy e?ioey caoai?thaaiiy.

Caaaeaiiy aeine?aeaeaiiy:

1. Aecia/eoe ieoiio aaao ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o
i?aee?oe?a na?aae ?ioeo ee?i?/ieo oi?i eaaaiaaiai ooaa?eoeueico, aea/eoe
a?eiai-noaoaaee ? nioe?aeueiee neeaae oai?eo.

2. Aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a ca no/anieo oiia.

3. Aea/eoe aoaeoeai?noue e?eoaaiiy ?io?eueo?aoeaiiai ooaa?eoeueico
eaaaiue o i?aee?oe?a.

4. Aea/eoe ee?i?/ia cia/aiiy ?ioiieia?/ii? ?aaeoeaiino?,
ooieoe?iiaeueiiai noaio ueoiaeaeii? oa iaaeie?eiaeo caeic i?e
?io?eueo?aoeaiiio ooaa?eoeueic? eaaaiue o i?aee?oe?a.

5. Aea/eoe ? aecia/eoe aeaye? ia?aiao?e iaoiii?oico ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a c 1973 aei 1995 ?ieo.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Ia i?aenoaa? ??/ieo ca?o?a ca
inoaii? 7 ?ie?a anoaiiaeaii ieoiio aaao ?io?eueo?aoeaiiai ooaa?eoeueico
eaaaiue o i?aee?oe?a na?aae ?ioeo ee?i?/ieo oi?i caoai?thaaiiy.

Aia?oa cae?eniaii aea/aiiy iniaeeainoae ?io?eueo?aoeaiiai ooaa?eoeueico
eaaaiue o i?aee?oe?a ca no/anieo oiia c o?aooaaiiyi noaio ?ioiieia?/ii?
?aaeoeaiino? , ooieoe?iiaeueiiai noaio ueoiaeaeii? oa iaaeie?eiaeo
caeic.

Aea/aii ?aioaaiieia?/io ea?oeio ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue
o i?aee?oe?a c o?aooaaiiyi eiai ee?i?ei-?aioaaiieia?/ieo aa??aio?a.

Aecia/aii cia/ou?noue eiioaeoo c oai?eie ia ooaa?eoeueic ? nooiaith
ooaa?eoe?iiai? /ooeeaino? o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii
eaaaiue.

Aea/aii ? anoaiiaeaii aeaye? ia?aiao?e iaoiii?oico ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a ca inoaii? ?iee.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Aeai? i?i iniaeeaino?
aeyaeaiiy, ee?i?ee, ia?aa?ao e aoaeoeaiino? e?eoaaiiy ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a ca no/anieo oiia c o?aooaaiiyi noaio
?ioiieia?/ii? ?aaeoeaiino? aeiaiaeyoue iaiao?aei?noue iie?aueoe
i?aai?caoe?th i?iaaaeaiiy ui??/ii? ooaa?eoe?iiae?aaiinoeee oa ?? yeino?,
aaeineiiaethaaoe i?ioeooaa?eoeueicio ?iaioo c i?aee?oeaie c ina?aaee?a
ooaa?eoeueicii? ?ioaeoe??, ui ni?eyoeia ?aii?e ae?aaiinoeoe?
caoai?thaaiiy.

I?iaiaey/e e?eoaaiiy, iaiao?aeii a?aoiaoaaoe ia eeoa
ee?i?ei-?aioaaiieia?/i? iniaeeaino? caoai?thaaiiy, aea e iayai?noue
eiioaeoo c oai?eie ia ooaa?eoeueic, eiai oa?aeoa?, a oaeiae nooi?iue
/ooeeaino? aei ooaa?eoe?io aeey ?iaeea?aeoaeueiiai i?aeoiaeo ?
i?ecia/aiiy aaeaeaaoieo ao?io?iiieo ? iaoiaaiaoe/ieo cania?a, ui
ni?eyoeeai a?aeaeaaoeiaoueny ia aoaeoeaiino? e?eoaaiiy ? e?ioeaaeo
?acoeueoaoao caoai?thaaiiy.

Ciaiiy ee?i?ei-?aioaaiieia?/ieo iniaeeainoae ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a aea? iiaeeea?noue iie?aueoe ye?noue
aeeoa?aioe?aeueii? ae?aaiinoeee ooaa?eoeueico ? ianiaoeeo?/ieo
caiaeueieo caoai?thaaiue eaaaiue, ui ia? ciaioeoe e?euee?noue oai?eo ?c
caiouaieie ? oneeaaeiaieie oi?iaie ooaa?eoeueico eaaaiue o in?a oe???
a?eiai? eaoaai???.

Iniaenoee aianie aeena?oaioa iieyaa? o ?ic?iaoe? an?o iaoeiaeo
?acoeueoao?a. Aaoi? ?ic?iaeea i?ia?aio aeine?aeaeaiiy, aecia/eea iaoo oa
caaaeaiiy ?iaioe. Aeeiiaea a?aea?? oa ianoaaeaiiy 240 i?aee?oe?a, c ieo
186 i?aee?oe?a, oai?eo ia ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue – 148
neeaee iniiaio a?oio ? 38 – a?oio ii??aiyiiy, 15 – c aiaieuaaei
ooaa?eoeueicii eaaaiue, 39 i?aee?oe?a, ia ?io?eiaaieo ooaa?eoeueicii
neeaaeaee eiio?ieueio a?oio. Naiino?eii i?iaiaeeea aiae?c iaaee/ii?
aeieoiaioaoe??, ?ioa?i?aoaoe?th ee?i?/ieo, ?aioaaiieia?/ieo,
?ioiieia?/ieo oa ai?iiiaeueieo aeine?aeaeaiue o ii??aiyii? c
e?oa?aoo?ieie aeaieie oa ?o noaoenoe/ia ii?aoethaaiiy, noi?ioethaaea
aeniiaee oa i?aeoe/i? ?aeiiaiaeaoe??.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy o i?aeoeeo. ?acoeueoaoe
?iaioe ai?iaaaeaeaii o i?aeoeeo iaeaniiai aeeoy/i-i?aee?oeiaiai
ooaa?eoeueiciiai naiaoi??th, iaeaniiai i?ioeooaa?eoeueiciiai
aeeniaina?o, i?ioeooaa?eoeueiciiai aeeniaina?o ? 1 i. Oa?eiaa. Iniiai?
iieiaeaiiy aeena?oaoe?? aeei?enoiaothoueny i?e i?iaaaeaii?
iaaeaaia?/iiai i?ioeano ia eaoaae?? aeeoy/i? ooec?ao??? ?
ioeueiiiieia?? Oa?e?anueeiai ?inoeoooo oaeineiiaeaiiy e?ea??a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aena?oeaii e iaaiai?aii ia Anioe?aoe?? ooec?ao??a Oa?e?anueeiai
iaoeiai-iaaee/iiai oiaa?enoaa o 1994 — 1995 ??. Aiie aeiiia?aeaeeny ia
Oe?a?inuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? (Oa?e?a, 15 — 16 aa?aciy
1995 ?.), ia?aae?-nai?ia?? ooec?ao??a ? ioeueiiiieia?a Oe?a?ie
(Oa?iii?eue, 1997).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 11 ?ia?o.

Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?th aeeeaaeaii ia 157
noi??ieao ae?oeiaaiiai oaenoo. Aiia neeaaea?oueny ?c anooio, iaeyaeo
e?oa?aoo?e, 5 ?icae?e?a aeanieo aeine?aeaeaiue, cae?i/aiiy, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo e?oa?aoo?e, yeee i?noeoue 267
aeaea?ae, c ieo 216 a?o/eciyieo ? 51 ?iicaiieo aaoi??a. Aeena?oaoe?th
?ethno?iaaii 39 oaaeeoeyie ? 1 5 iaethieaie.

CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy C iaoith aea/aiiy iniaeeainoae
?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a ianoaaeaii 240
/ieia?e 13 — 18 ?ie?a, na?aae yeeo 148 oai?eo ia ?io?eueo?aoeaiee
ooaa?eoeueic eaaaiue neeaee iniiaio a?oio; 38 i?aee?oe?a c aiaeia?/ieie
i?ioeanaie, ye? ia?aaoaaee o noaoe?iia?? iaeooaaeeniaina?o o 1972 — 1977
?ieao aoee a?oiith ii??aiyiiy aeey aea/aiiy ? aecia/aiiy aeayeeo
ia?aiao??a iaoiii?oico, 15 i?aee?oe?a c aiaieuaaei ooaa?eoeueicii
eaaaiue oaeiae aoee a?oiith ii??aiyiiy; 39 — ia ?io?eiaaieo
ooaa?eoeueicii i?aee?oe?a, aiaeia?/ieo ca noaooth ? a?eii iniiai?e
a?oi?, i?aaeee ca eiio?ieue.

E??i oiai, c iaoith aecia/aiiy ieoiii? aaae ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o aeacai?e a?eia?e a?oi? i?iaiae?ciaaii aeai?
??/ieo ca?o?a caoai?thaaiino? ia ooaa?eoeueic i?aai?a aeeoaiiy
i?aee?oe?a Oa?e?anueei? iaeano? ca 1990 — 1996 ?iee.

On? i?aee?oee i?e anooi? aei noaoe?iia?o ianoaaeoaaeeny c aeei?enoaiiyi
iaia’yceiaeo, aeiaeaoeiaeo ? oaeoeueoaoeaieo iaoiae?a ae?aaiinoeee. Aeey
aea/aiiy ?ioiieia?/ii? ?aaeoeaiino? canoiniaoaaany eiiieaen iaoiae?a,
yeee i?noea aecia/aiiy aeanoo?ainoi?iaoe?? e?ioioeeo?a c
o?oiaaiaaaethoei?iii (?AO c OAA) ? ooaa?eoe?iii (?AO c PPD), ca iaoiaeii
Bach, Hirschhorn [1963] o iiaeeo?eaoe?? I. I. A?eai?’?ai? e ?. ?.
Eiiaeyi [1972], i?ae?aooaaiiy e?eueeino? Oe?ioioeeo?a iaoiaeii
niiioaiiiai ?icaoeiooai?aiiy (A-?OE) E. O. *a?iooaiei ? ni?aaao. [1981],
aecia/aiiy ??aiy ?ioiiaeiaoe?i?a A, M, G, iaoiaeii ?aae?aeueii? aeeooc??
[Mancini at al, 1965] ? ai?no a?noai?io o ne?iaaooe? e?ia?
[E. O. *a?iooaiei, E. N. Eiainiaa, 1978]. Iieaciee iioeiaeaeaiiy
iaeo?io?e?a (III) aecia/aany ca iaoiaeii A. A. O?aaee?ia [1985] o
iiaeeo?eaoe?? A. Ae. sseiaaiea ? ni?aaao. [1988].

Ai?no a ieaci? e?ia? o??aio?iiiiai ai?iiio (OOA), o?eeiaeo??ii?io
(O3), o??ien?io (O4), ei?oecieo cae?enithaaee ?aae?i?ioiieia?/iei
iaoiaeii noaiaea?oieie oano-iaai?aie ?inoeoooo a?ii?aai?/ii? o?i??
Aeaaeai?? Iaoe A?ei?on?; o??i “Mallinkrodt” (O?A), oa “Sorin”
(O?aioe?y).

?ACOEUeOAOE AeINE?AeAEAIIss OA ?O AIAE?C

Aea/aii caaaeueio caoai?thaai?noue ia ooaa?eoeueic ia 100 oeny/
ianaeaiiy i?aee?oe?a Oa?e?anueei? iaeano? ca 1990 — 1996 ?iee, yea
eieeaaeany a?ae 11,38 o 1992 ?ioe? aei 23,02 o 1993 ?ioe?, ? caaaeaee
ia?aaeuoaaea o 2 — 4 ?ace caoai?thaai?noue ae?oae. E??i oiai, ia
i?aenoaa? aiae?co ??/ieo ca?o?a ca 1990 — 1996 ??. aecia/aii ieoiio aaao
?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a, ye? aeyaeai?
aia?oa, eio?ee neeaa 43,5 % ? aoa iaeaeuei o ii??aiyii? c ?ioeie
ee?i?/ieie oi?iaie; o ie?ai? ?iee a?i eieeaaany a?ae 25 % o 1990 ?ioe?
aei 66,7 % o 1995 ?ioe?, oiaoi a?aecia/a?oueny cia/ia eiai ca?eueoaiiy.

Na?aae ianoaaeaieo 148 i?aee?oe?a iniiaii? a?oie thiae?a ? ae?a/ao aoei
ia??aii — ii 74 /ieia?ea.

I?e aeyaeaii? caoai?thaaiiy o a?oe? 13 — 14 ?ie?a aoei 15 (10,14 %)
/ieia?e, 15 — 17 ?ie?a — 81 (54,7 %) i?aee?oie ? 18-??/ieo aoei 52
(35,14 %).

I?e aiae?c? a?eiai-noaoaaiai neeaaeo oai?eo ia ?io?eueo?aoeaiee
ooaa?eoeueic eaaaiue i?aee?oe?a c’yniaaii, ui o a?oe? 13 — 15 ?ie?a
/ano?oa, i?ae o 4 ?ace, oai??thoue ia oeth oi?io ooaa?eoeueico ae?a/aoa
(15,54 %), i?ae thiaee (3,39 %); o a?oe? 16 — 17 ?ie?a thiaee ? ae?a/aoa
oai??thoue iaeiaeiai /anoi (25 ? 20 % a?aeiia?aeii), iaeiae o 18 ?ie?a
aeaui /ano?oa oai??thoue thiaee (21,06 %), ai?ae ae?a/aoa (13,5 %).

C oeo, ui caoai??ee, 79 (53,38 %) i?aee?oe?a aoee iaoeaioeyie i?noa, 69
(46,6 %)  — naea.

O/i? (oe?e, oaoi?eoi?a, aoc?a, IOO) neeaee a?eueo?noue — 73 %, ?aooa
(27 %) aoee i?aoethth/eie.

O 60 (40,5 %) i?aee?oe?a, yeeo niinoa??aaee, a?aei?/aany eiioaeo c
oai?eie ia ooaa?eoeueic, c yeeo o 61,7 % a?i aoa iino?eiei ? o 38,33 %
— ia??iaee/iei.

O a?eueoi? /anoeie i?aee?oe?a — 79 (53,38 %) — ?io?eueo?aoeaiee
ooaa?eoeueic eaaaiue aoei aeyaeaii i?e oethi?ia?ao?/iiio ianoaaeaii?, ?
eeoa o 3 (2,03 %) /ieia?e aoei aecia/aii i?e ooaa?eoe?iiae?aaiinoeoe?; o
66 (44,59 %) oai?eo i?ioean aoei aeyaeaii i?e caa?iaii? aei caaaeueii?
iaaee/ii? ia?aae?, a?aecia/aeeny ??ci? nea?ae ia ii?ooaiiy noaio
caei?ia’y. Cia/iee a?aenioie ae?aaiinoeee ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a «ca caa?oaiiyi» iio?aao? ieeueii?
oaaae, iniaeeai ca no/anieo oiia, eiee a?eueoa oaaaa ia? i?eae?eyoeny
naia i?io?eaeoe/iiio iai?yieo.

I?euaii? ciaee i?ney aaeoeeiaoe?? ? ?aaaeoeeiaoe?? AOeAE aoee a?aenooi?
o 22 (14,86 %) oai?eo, o 126 (85,14 %) aiie aoee, i?e/iio o a?eueoino? c
ieo — o 63 (62,8 %) i?aee?oe?a — iaaaeeeeie (1 — 4 ii o ae?aiao??),
ui na?ae/eei i?i iaaeinoaoith ye?noue uaieaiue. Iiaeia i?eionoeoe, ui
iaiiaiioe?ii?noue ?ioiii?io?eaeoeee a?ae?a?aea iaaio ?ieue o aeieeiaii?
caoai?thaaiiy o i?aee?oe?a, ca yeeie cae?enithaaany iaaeyae.

C 74 /ieia?e, ye? iaee aeai? i?i ?acoeueoaoe ui??/ii?
ooaa?eoe?iiae?aaiinoeee, o 32 (43 %) caoai?thaaiiy aeieeei ia oii?
a??aaeo ooaa?eoe?iiai? ?aaeoe??, oiaoi a ia??iae ia?aeiii?
ooaa?eoeueicii? ?ioaeoe??.

I?e ia’?eoeaiiio ianoaaeaii? i?aee?oe?a c ?io?eueo?aoeaiei
ooaa?eoeueicii eaaaiue anoaiiaeaii, ui aa?iii?eiee o?ce/iee ?icaeoie
iaee 70 % oai?eo, o 30 % niinoa??aaeeny a?aeoeeaiiy o o?ce/iiio
?icaeoeo, c yeeo o 20,5 % aoea cieaeaiith iana o?ea, iaaeeeoeiao iano
iaee 9,5 % i?aee?oe?a.

Aino?ee ii/aoie caoai?thaaiiy a?aecia/aany o 43 (29,05 %) oai?eo;
iae/ano?oa a?aei?/aany i?aeaino?ee ii/aoie caoai?thaaiiy — o 50
(33,78 %) /ieia?e; aacneiioiiiee — o 44 (29,72 %) oa ?iaia?oeaioiee —
o 11 (7,43 %).

I?iyae ?ioieneeaoe?eiiai neiae?iio niinoa??aaeeny o 84 (56,76 %)
i?aee?oe?a; eaoaeue a?aecia/aany o 44 (29,73 %) oai?eo, o 36 (24,32 %)
a?i aoa c iie?ioeiiyi, o 8 (5,41 %) — nooei.

A?eue o a?oaeyo niinoa??aaany o 25 (16,89 %) i?aee?oe?a.

I?e noaoaeonoe/iiio aeine?aeaeaii? oei?i/aiiy ia?eooi?iiai oiio
a?aecia/aeiny o 34,5 % oai?eo, ci?ie oa?aeoa?o aeeoaiiy o 51,35 %,
/ano?oa aiii aoei ineaaeaiei ? c aei?noeei a?aeo?ieii; o?eie
aeneooiaoaaeeny eeoa o 42 (28,38 %) i?aee?oe?a, ooi oa?oy ieaa?e — o
4,7 %.

O ?acoeueoao? ee?i?ei-?aioaaiieia?/iiai ianoaaeaiiy anoaiiaeaii, ui o 70
(43,7 %) i?aee?oe?a i?ioean aoa i?aaenoaaeaiee eeoa ?io?eueo?aoeaieie
i?iyaaie, o 74 (50 %) aeyaeyeany oaca ?iciaaeo, c ieo o 28 (18,92 %)
/ieia?e ii?yae c ?iciaaeii niinoa??aaeany oaca ian?iai?iiy; o?eueee
ian?iai?iiy aac anoaiiaeaiiai ?iciaaeo cono??/aeiny ??aeei — o 4
(2,7 %).

??ciiiai?oi?noue iaoiaaiaoe/ieo oaeoi??a ?io?eueo?aoeaiiai ooaa?eoeueico
eaaaiue, iie?ii?o?ci ? cia/ia aeeiai?/i?noue oeaieiieo ?aaeoe?e
iaoiiaeththoue iaiaeii??aeio ee?i?ei-?aioaaiieiai?/io ea?oeio oe???
ee?i?/ii? oi?ie ooaa?eoeueico ? aeathoue ciiao aeae?eeoe ie?ai?
ee?i?ei-?aioaaiieia?/i? aa??aioe, ye? iaeoi/i?oa aecia/athoue
?iciianthaeaeai?noue ooaa?eoeueiciiai i?ioeano.

O 17 (11,49 %) i?aee?oe?a anoaiiaeaii eiaoey?iee ?io?eueo?ao, o 18
(12,16 %) — e?oaeee, o 90 (61,81 %) — oia?iaeaeiee, o 13 (8,79 %) —
eia?o, o 6 (4,06 %) — ia?enoeenno?eo ? o 4 (2,70 %) — eacaicia
iiaaiii?y. O ia?aaaaeii? a?eueoino? (76,35%) i?aee?oe?a a?aei?/aany
?iciianthaeaeaiee i?ioean ? iaio i?ae o 1/4 (23,65 %) oai?eo
a?aecia/aeiny iaiaaeaia o?aaeaiiy eaaaiue.

Anoaiiaeaii, ui e?oaeee ?io?eueo?ao, ia?enoeenno?eo ? eia?o /ano?oa
niinoa??aaeeny o thiae?a, ai?ae o ae?a/ao (77,7 %, 66,6 % a?aeiia?aeii),
a eiaoey?iee ?io?eueo?ao /ano?oa ae?aaiinooaaany o ae?a/ao (58,8 %);
eacaicia iiaaiii?y niinoa??aaeany o?eueee o ae?a/ao.

I?e aeine?aeaeaii? iie?ioeiiy aaeoa??iaeae?eaiiy aeyaeaii o 69 (46,62 %)
oai?eo, i?e/iio o 20 (13,51 %) c ieo aiii aoei /eneaiiei.

A aiae?c? e?ia? o 19 (12,84 %) /ieia?e aoei aeyaeaii aiai?th, o 37
(25 %) i?aee?oe?a niinoa??aaany eaeeioeeoic ? o 56 (37,8 %) iaei i?noea
c?ooaiiy iaee/eiyaea?ieo eaeeioeeo?a e?ai?o/. O 19,4 % oai?eo
a?aecia/aany e?ioioeeoic ? o 42,4 % — e?ioioeeoiiai?y; o 9,5 % —
iiiioeeoic ? o 30,9 % — iiiioeeoiiai?y. Oaeei /eiii, ci?ie c aieo
eaeeioeeoa?ii? oi?ioee i?e ?io?eueo?aoeaiiio ooaa?eoeueic? eaaaiue o
i?aee?oe?a niinoa??aaeeny o 42 % oai?eo, ? iae/ano?oa cono??/aeany
e?ioioeeoiiai?y.

Aeai? ooaa?eoe?iiae?aaiinoeee ca i?iaith Iaioo c 2 OI aeaee ciiao
aeyaeoe o 54 % oai?eo iii??io /ooeea?noue aei ooaa?eoe?io (5 — 12 ii), o
28,74 % oeo, ui i?aeeyaaee niinoa?aaeaiith, — ae?aaeaio (13 — 16 ii),
o 17,24 % i?aee?oe?a — a?ia?a?a?/io. Iayai?noue a?ia?a?a?/ii?
/ooeeaino? aei ooaa?eoe?io o i?aee?oe?a c ?io?eueo?aoeaiei
ooaa?eoeueicii eaaaiue noi?iaiaeaeoaaeany cieaeaiiyi ianiaoeeo?/ii?
?aaeoeaiino? ?AO c OAA — (28,332,8 )% o ii??aiyii? c oai?eie, ye? iaee
iii??io e ae?aaeaio /ooeea?noue aei ooaa?eoe?io ?AO c OAA —
(39,03,57) %, ?0,05, ui aeioe?eueii o?aoiaoaaoe i?e e?eoaaii? oaeeo
oai?eo.

I?ioyaii aaaaoueio ?ie?a iniiao ae?aaiinoeee ooaa?eoeueico neeaaea?
?aioaaiieia?/iee iaoiae aeine?aeaeaiiy [I. A. Oiiaiei, 1995], oiio ie
aeaoaeueii aea/eee ?aioaaiieia?/io ea?oeio ?io?eueo?aoeaiiai
ooaa?eoeueico eaaaiue o i?aee?oe?a, ye? i?aeeyaaee niinoa?aaeaiith.

Ooaa?eoeueiciee i?ioean aeaui /ano?oa eieae?coaaany o i?aa?e eaaai?
(50,1 %), i?ae o e?a?e (38,52 %), o 11,49 % oai?eo aoee o?aaeai? iaeaea?
eaaai?. O ia?aaaaei?e a?eueoino? aeiaaee?a (83,79 %) a?aei?/aeiny
?icoaooaaiiy ?io?eueo?ao?a o aa?oi?o aeieyo eaaaiue, o ieaei?e aeie?
i?ioean eieae?coaaany o eiaeiiai aeanyoiai (10,14 %). ?cieueiaaia
o?aaeaiiy na?aaeiuei? aeie? ia niinoa??aaeiny, a niieo/aeiny c
eieae?caoe??th i?ioeano o aa?oi?e aeie?.

*ano?oa iaei i?noea ?cieueiaaia o?aaeaiiy ae?oaiai naaiaioo (26,09 %),
aeaui ??aeoa — oinoiai (9,57 %), aeae? ca /anoioith o?aaeaiiy eaeooue
ia?oee (6,96 %) ? o?ao?e (3,48 %) naaiaioe. A?eueo i?ae o iieiaeie
oai?eo (53,91 %) ?io?eueo?aoeai? ci?ie eieae?coaaeeny o aeae?eueeio
naaiaioao.

C 74 i?aee?oe?a c iayai?noth ?iciaaeo o 51,79 % a?aecia/aany na?aaei?e
?ici?? ii?iaeiei (2 — 4 ni o ae?aiao??), o 41 % ii?iaeieie aoee iaeiai
?ici??o (aei 2 ni o ae?aiao??) ? o 7,14 % oai?eo ?ici?? ii?iaeiei
ia?aaeuoaaa 4 ni o ae?aiao??.

?iciaae eaaaiaai? oeaieie iaa i?noea o an?o oai?eo c eacaiciith
iiaaiii??th, iaeaea o an?o (12 c 13) c eia?oii ? o 56,6 % i?aee?oe?a c
oia?iaeaeiei ?io?eueo?aoii; iae??aeoa (17,64 %) a?i cono??/aany o oai?eo
c eiaoey?iei ee?i?ei-?aioaaiieia?/iei aa??aioii. I?e ia?enoeenno?eo?
?iciaae ia a?aei?/aany. Ii?yae c ?iciaaeii o an?o oai?eo c eacaiciith
iiaaiii??th, iaeaea o an?o c eia?oii ? a?eueo i?ae o 1/3 c oia?iaeaeiei
?io?eueo?aoii niinoa??aaeiny ian?iai?iiy.

A?iioineii?/ia aeine?aeaeaiiy i?iaiaeeeiny 78 i?aee?oeai c
?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue, niaoeeo?/ia o?aaeaiiy a?iio?a
aeyaeyeiny o 65 (83,33 %) /ieia?e; iae/ano?oa aiii niinoa??aaeiny o
oai?eo c ia?enoeenno?eoii (66,6 %) ? eacaiciith iiaaiii??th (50 %).
Iaeiae niaoeeo?/ia o?aaeaiiy a?iio?a cono??/aeiny aeineoue /anoi aei
66,6% i?e an?o ??ciiaeaeao ee?i?ei-?aioaaiieia?/ieo aa??aio?a
?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a.

Iayai?noue eiioaeoo c oai?eie ia ooaa?eoeueic ? eiai oa?aeoa?
a?aeaeaathoueny ia iaoe?iino? o?aaeaiiy i?e ?io?eueo?aoeaiiio
ooaa?eoeueic? eaaaiue. O oai?eo, ye? iaee iino?eiee ooaa?eoeueiciee
eiioaeo, /ano?oa (81,0 %) niinoa??aaeeny i?ioeane o aeaeyae?
oia?iaeaeiiai ?io?eueo?aoo ? eia?oo, o oie /an ye i?e ia??iaee/iiio
eiioaeo? aeacai? ee?i?ei-?aioaaiieia?/i? aa??aioe cono??/aeeny o 56,51 %
i?aee?oe?a. O in?a, ye? iaee ia??iaee/iee eiioaeo c oai?eie ia
ooaa?eoeueic, oaca ?iciaaeo aoea ae?aaiinoiaaia o 34,78 % aeiaaee?a,
oiae? ye o i?aee?oe?a c iino?eiiai ooaa?eoeueiciiai eiioaeoo ?iciaae
anoaiiaeaii o 59,45 %.

Cia/ou?noue eiioaeoo c oai?eie ia ooaa?eoeueic ? iai/iith i?e aea/aii?
?ioiieia?/ii? ?aaeoeaiino? o oai?eo, ye? i?aeeyaaee iaaeyaeo. Iayai?noue
eiioaeoo c oai?eie ia ooaa?eoeueic noi?iaiaeaeoaaeany cieaeaiiyi
ianiaoeeo?/ii? ?aaeoeaiino? ?AO c OAA — (39,49,69) %; A-?OE —
(34,229,6) %; Ig A — (138,013,0) ia/100 ie o i?aee?oe?a, ye? oai??ee
ia ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue, o ii??aiyii? c eiio?ieai ?AO c
OAA — (58,60,9) %; ?0,01; A-?OE — ( 56,41,08) %; ?0,05; Ig A —
(230,418,23) ia/100 ie; ?0,001, oiae? ye o oai?eo aac anoaiiaeaiiai
eiioaeoo oe? iieacieee ia a?ae??ciyeeny a?ae eiio?ieth; ??aaiue
a?noai?io o eiioaeoieo oai?eo aoa aeuee o ii??aiyii? c iniaaie aac
anoaiiaeaiiai eiioaeoo (0,7690,33) iea/ie ? (0,6090,23) iea/ie
a?aeiia?aeii, ?0,05; oea ia? o?aoiaoaaoeny o eiiieaeniiio e?eoaaii?
oaeeo oai?eo.

?io?eueo?aoeaiee ooaa?eoeueic eaaaiue, aeyaeaiee i?ae /an caa?iaiiy aei
e?ea?y, oa?aeoa?ecoaaany iaoe?i?noth o?aaeaiiy o aeaeyae? oia?iaeaeiiai
?io?eueo?aoo, eia?oo, ia?enoeenno?eoo ? eacaicii? iiaaiii?? o 86,35 %
i?aee?oe?a ? oacith ?iciaaeo o 66,6 % oai?eo, o oie /an ye i?e
oethi?ia?ao?/iiio aeyaeaii? oe? ee?i?ei-?aioaaiieia?/i? aa??aioe
niinoa??aaeeny o 67,08 % i?aee?oe?a ? oaca ?iciaaeo — o 36,7 % oai?eo,
ui caea?oueny eia?/iei.

Aino?ee ? i?aeaino?ee ii/aoie caoai?thaaiiy niinoa??aaany o an?o
i?aee?oe?a c eia?oii ? eacaiciith iiaaiii??th, o 67,7 % oai?eo c
oia?iaeaeiei ?io?eueo?aoii e o eiaeiiai o?aoueiai c ia?enoeenno?eoii; o
in?a c eiaoey?iei ? e?oaeei ?io?eueo?aoii oaeee ii/aoie caoai?thaaiiy
cono??/aany ??aeei — 5,5 %. Iaeiae iaa?oue i?e iaoe?ieo i?ioeanao
iiaeeeaee aacneiioiiiee (16,6 — 26,6 %) oa ?iaia?oeaioiee (5,5 —
33,3 %) ia?aa?a caoai?thaaiiy, ui noai?th? o?oaeiiu? o aeyaeaii? oaeeo
oai?eo.

Aeai? ee?i?/iiai ianoaaeaiiy aeaee ciiao anoaiiaeoe, ui nea?ae
?ioieneeaoe?eiiai oa?aeoa?o a?aecia/aee 56,75 % oai?eo; aiie aeyaeyeeny
o an?o i?aee?oe?a c eacaiciith iiaaiii??th (100 %); iae/ano?oa c eia?oii
(84,6 %) ? ia?enoeenno?eoii (83,3 %), ??aeoa — i?e oia?iaeaeiiio
?io?eueo?ao? (57,7 %) ? eiaoey?iiio (47,05 %) ? iae??aeoa — o
i?aee?oe?a c e?oaeei ?io?eueo?aoii.

Eaoaeue o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue
niinoa??aaany o eiaeiiai o?aoueiai (29,72 %), i?e/iio o 24,32 % c ieo
a?i aoa aieiaee ? o 5,4 % — nooee. Eaoaeue c iie?ioeiiyi /ano?oa
niinoa??aaany o oai?eo c eacaiciith iiaaiii??th (50 %) ? eia?oii
(53,84 %), ??aeoa — i?e ia?enoeenno?eo? (33,3 %) oa oia?iaeaeiiio
?io?eueo?ao? (21,11 %), iae??aeoa i?e eiaoey?iiio (23,52 %) ? e?oaeiio
(11,1 %).

A?eue o a?oaeyo /ano?oa a?aei?/aee i?aee?oee c eacaiciith iiaaiii??th
(50 %), eia?oii (30,76 %), ??aeoa — i?e ia?enoeenno?eo? (16,6 %) ?
oia?iaeaeiiio ?io?eueoo?ao? (17,7 %), cian?i ia aeacoaaee ia aieueiaee
neiae?ii oai?? c eiaoey?iei ?io?eueo?aoii.

I?ae /an aeine?aeaeaiiy ?ioiieia?/ii? ?aaeoeaiino? anoaiiaeaii, ui
?io?eueo?aoeaiee ooaa?eoeueic eaaaiue noi?iaiaeaeo?oueny i?aeaeuaiiyi
??aiy ?ioiiniaoeeo?/iiai iieacieea: III — (0,150,05) %, eiio?ieue —
(0,010,002) %, ?0,001 ? cieaeaiiyi ?AO c PPD aei eiio?ieueieo oeeo? —
(1,640,14) %, eiio?ieue — ( 1,30,2) %, ?0,05.

On? iieacieee ianiaoeeo?/ii? ?aaeoeaiino? aoee cieaeai?, e??i iieaciee?a
a?noai?io ? Ig G: ?AO c OAA — (36,562,36) %, eiio?ieue — (58,60,9)%,
?0,001; A-?OE — (36,410,7) %, eiio?ieue — (56,41,08) %, ? = 0,05; Ig
A — (152,3112,85) ia/100 ie, eiio?ieue — (230,418,23) ia/100 ie,
?0,001; Ig M — 94,317,66 ia/100 ie, eiio?ieue — (1126,46) ia/100 ie,
?0,05; ai?no Ig G ia?aaoaaa o iaaeao ii?ie — (912,084,6) ia/100 ie,
eiio?ieue — (984,053,5) ia/100 ie, ?0,05; ??aaiue a?noai?io ??cei
i?aeaeuaiee — (0,7030,3) iea/ie, eiio?ieue — (0,0250,004) iea/ie,
?0,05.

O i?aee?oe?a, ye? iaee i?ioeane a?eueoi? i?ioyaeiino? (oia?iaeaeiee
?io?eueo?ao, eia?o, ia?enoeenno?eo ? eacaicio iiaaiii?th), a?aecia/aeiny
aeinoia??ia cieaeaiiy ianiaoeeo?/ii? ?aaeoeaiino? (A-?OE, Ig A, Ig M, Ig
G) o ii??aiyii? c iniaaie, o yeeo a?aeaoaaeeny i?ioeane iaei?
i?ioyaeiino? (eiaoey?iee ? e?oaeee ?io?eueo?aoe); III i?e i?ioeanao
??cii? i?ioyaeiino? aoa i?aeaeuaiee, ??aaiue aeanoiooai?aiiy c PPD i?e
iaoe?ieo i?ioeanao aei??aithaaa eiio?ieth, a i?e iaiaaeaieo aoa
aeinoia??ii aeua.

Iayai?noue aeano?oeoe?? o eaaaiaa?e oeaiei? ?noioii ia aieeaaea ia noai
?ioiieia?/ii? ?aaeoeaiino?, i?e ii??aiyii? ?? iieaciee?a o i?aee?oe?a c
?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue aac ?iciaaeo ? c iayai?noth
?iciaaeo aeinoia??ii? ??cieoe? ia aoei, e??i iieacieea ?AO c PPD — a?i
aeinoia??ii ieae/ee o in?a c iayai?noth ?iciaaeo (1,8650,18) % ?
(1,2370,206) %, ?0,05.

I?e ?io?eueo?aoeaiiio ooaa?eoeueic? eaaaiue ia a?aei?io a?ae
aiaieuaaiai ? a?eueo cia/ia ciaioaiiy aeanoiooai?thaaiiy c PPD ? OAA,
oiaoi ooieoe?iiaeueiee noai e?ioioeeo?a i?e ?io?eueo?aoeaiiio
ooaa?eoeueic? eaaaiue ci?iaii a?eueo cia/ii.

I?e aeine?aeaeaii? ooieoe?iiaeueiiai noaio ueoiaeaeii? oa iaaeie?eiaeo
caeic o i?aee?oe?a, ye? niinoa??aaeenue, aeyaeaii i?aeaeuaiiy ai?noo OOA
– (12,64,09) II/e, eiio?ieue – (2,480,16) II/e, ?<0,01; O4 – (100,97,9) iiieue/e, eiio?ieue – (84,63,57) iiieue/e, ?<0,05, ei?oecieo – (599,463,7) iiieue/e, eiio?ieue – (382,428,3) iiieue/e, ?<0,01, ui na?ae/eoue i?i iai?oaeaiee ooieoe?iiaeueiee noai nenoai, ye? aeine?aeaeoaaeenue, oa aeicaiey? oa?aeoa?ecoaaoe aeaiee noai, ye no?an. I?e aiaieuaaiio ooaa?eoeueic? eaaaiue ia a?aei?io a?ae ?io?eueo?aoeaiiai, ??aaiue ei?oecieo a ii??aiyii? c eiio?ieai, aeinoia??ii ia ci?iaiee (498,774,8) iiieue/e, oiaoi i?e ?io?eueo?aoeaiiio ooaa?eoeueic? eaaaiue o i?aee?oe?a niinoa??aathoueny a?eueo ae?aaeai? ci?ie ai?iiiaeueiiai i?io?eth. Iniiaiee eo?n oa?ai?? o noaoe?iia?? i?aee?oeai, ui i?aeeyaaee niinoa?aaeaiith, i?iaiaeeee o a?aeiia?aeiino? ?c caaaeueieie i?eioeeiaie e?eoaaiiy ? o?i?ioa?ai??. O?eaae?noue noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue o 16,88 % neeaea aei 4-o i?nyoe?a, o 19,58 % - a?ae 4 aei 6 i?nyoe?a, o 27,05 % - a?ae 6 aei 8 i?nyoe?a, o 11,49 % - a?eueoa 10 i?nyoe?a. O i?ioean? e?eoaaiiy iinooiiai ciaioeeeny neiioiie ?ioieneeaoe?? ? /a?ac 3 i?nyoe? ia aecia/aeeny o an?o, e??i iaei??? oai?i? c eacaiciith iiaaiii??th. Eaoa?aeuei? ci?ie a eaaaiyo ia?anoaee aeneoooaaoeny o an?o oai?eo, e??i iaei???, /a?ac 2 - 3 i?nyoe? a?ae ii/aoeo e?eoaaiiy. Iieacieee oi?ioee e?ia? ii?iae?coaaeeny a on?o oai?eo ia 6 i?nyoe? a?ae ii/aoeo e?eoaaiiy. Ia oii? i?iaaaeaiiai e?eoaaiiy o 50 (72,46 %) oai?eo c iayai?noth aaeoa??aiaeae?eaiiy IAO ia?anoaee aeyaeyoeny /a?ac 3 i?nyoe?, o 57 (82,6 %) /ieia?e  - ia 6 i?nyoeue a?ae ii/aoeo e?eoaaiiy. Ia?aae aeieneith c? noaoe?iia?o IAO ia aeyaeyeany o 68 (98,5 %) i?aee?oe?a. I?e aiae?c? aoaeoeaiino? e?eoaaiiy o i?aee?oe?a, ye? i?aeeyaaee iaaeyaeo, ca ?aioaaiieia?/ieie aeaieie anoaiiaeaii, ui /a?ac 6 i?nyoe?a cia/ia ?icniieooaaiiy ?io?eueo?aoeaieo ci?i niinoa??aaeiny o 70,94 % oai?eo, a ii?iaeieie ?iciaaeo ia oeae /an caoyaeeny o 67,56 %. Ia?aae aeieneith c? noaoe?iia?o ii?iaeieie caoyaeeny o 98,65 % oai?eo, ui aeicaiey? aiai?eoe i?i aenieo aoaeoeai?noue e?eoaaiiy oe??? ee?i?/ii? oi?ie o in?a i?aee?oeiaiai a?eo. I?e aeine?aeaeaii? ?ioiieia?/ii? ?aaeoeaiino? o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue o i?ioean? e?eoaaiiy anoaiiaeaii, ui III, yeee aoa cia/ii ca?eueoaiee aei e?eoaaiiy o ii??aiyii? c eiio?ieai, aeinoia??ii cieaeoaaany o?eueee /a?ac 9 i?nyoe?a e?eoaaiiy - (0,150,05) ? (0,0710,05), eiee ??cieoey c eiio?ieai ia noaea aeyaeyoeny (0,010,002). ??aaiue aeanoiooai?aiiy c PPD, ui aoa cieaeaiee aei e?eoaaiiy, o i?ioean? e?eoaaiiy iinooiiai i?aeaeuoaaany, i?e/iio o?eueee /a?ac 6 ? 9 i?nyoe?a a?i aeinoia??ii a?ae??ciyany a?ae aeo?aeiiai ? aoa iaeaeuei /a?ac 9 i?nyoe?a e?eoaaiiy (1,660,14) % ? (5,21,28) %, a?aeiia?aeii, ?0,01. Iieaciee A-?OE, ui aoa cia/ii cieaeaiee aei e?eoaaiiy (36,562,36) %, iinooiiai i?aeaeuoaaany o i?ioean? e?eoaaiiy, aea iaa?oue /a?ac 9 i?nyoe?a oa?ai?? (48,012,93) % a?i ia aeinyaioa ??aiy eiio?ieueiiai (56,41,08) %, ? = 0,05. Ai?no Ig A, ui aoa cia/ii ciaioaiee aei e?eoaaiiy (152,3112,85) ia/100 ie, iinooiiai ca?eueooaaany o i?ioean? i?iaaaeaiiy iniiaiiai eo?no e?eoaaiiy, ? aaea /a?ac 6 i?nyoe?a (159,8596,24) ia/100 ie e?euee?noue Ig A ia a?ae??ciyeany a?ae eiio?ieth (230,418,23) ia/100 ie, ?0,05. ??aaiue Ig M oaeiae aoa cieaeaiee aei e?eoaaiiy (94,3127,66) ia/100 ie ii??aiyii c eiio?ieai (112,06,46) ia/100 ie, /a?ac 3 i?nyoe? (87,5528,43) ia/100 ie ??cieoey c eiio?ieai ia noaea aecia/aoeny. E?euee?noue Ig J ? aei ? a i?ioean? e?eoaaiiy ia a?ae??ciyeany a?ae eiio?ieueieo oeeo?. ??aaiue a?noai?io aei e?eoaaiiy aoa cia/ii aeua ii?ie (0,7030,4) iea/ie; eiio?ieue - (0,030,008) iea/ie, ?0,05, a i?ioean? e?eoaaiiy a?i aeaui ciaioeany (0,540,46) iea/ie, ?0,05. I?e aeine?aeaeaii? iieaciee?a ai?iiiaeueiiai i?io?eth o i?aee?oe?a, ui niinoa??aaeenue a i?ioean? e?eoaaiiy anoaiiaeaii, ui ??aaiue OOA(o??aio?iiiiai ai?iiio), cia/ii ca?eueoaiee aei e?eoaaiiy (12,64,09) II/e, eeoaany i?aeaeuaiei ia i?ioyc? 6 i?nyoe?a e?eoaaiiy oa ii?iae?coaaany eeoa /a?ac 9 i?nyoe?a (2,050,43) II/e, eiee ??cieoey c eiio?ieai (2,40,16) II/e iaeaea cieeea.. Ai?no O3 (o?eeiaeo??ii?io) ? aei, ? ia i?ioyc? anueiai ia??iaeo e?eoaaiiy caeeoeany a iaaeao ii?ie, ca aeeeth/aiiyi 6-i?ny/iiai no?ieo, eiee eiai ??aaiue i?aeaeueany. Ai?no O4 (o??ien?io) ? aei (100,97,6) iiieue/e, ? a i?ioean? e?eoaaiiy eeoeany cia/ii ca?eueoaiee, iaa?oue /a?ac 9 i?nyoe?a e?eoaaiiy cia/ii ia?aaeuoaaa ii?io (100,87,03) iiieue/e, eiio?ieue – (84,63,5) iiieue/e, ?<0,05. ??aaiue ei?oecieo oaeiae aoa i?aeaeuaiee ? aei (599,463,7) iiieue/e, ? ia i?ioyc? anueiai no?ieo e?eoaaiiy, i?e/iio c /anii niinoa??aaeany oaiaeaioe?y aei eiai ca?eueoaiiy oa iaeneiaeueiee ??aaiue eiai a?aecia/aany /a?ac 9 i?nyoe?a e?eoaaiiy (722,3140) iiieue/e, eiio?ieue – (38228,3) iiieue/e, ?<0,05. Iaaaaeai? aeai? na?ae/aoue, ui iieacieee ooieoe?iiaeueiiai noaio ueoiaeaeii? ? iaaeie?eiaeo caeic a i?ioean? e?eoaaiiy ii?iae?cothoueny iia?eueii, oea i?aeoaa?aeaeo? iai?oaeaiee noai iae?i-aoii?aeueii? nenoaie, ? aeicaiey? oa?aeoa?ecoaaoe aeaiee noai, ye no?an ? ocaiaeaeo?oueny c iaoiaaiaoe/ieie oyaeaiiyie i?i ooaa?eoeueiciee i?ioean. Aoaeoeai?noue e?eoaaiiy aecia/a?oueny ia eeoa no?ieii ?icniieooaaiiy caiaeueieo yaeu, aea e oa?aeoa?ii caeeoeiaeo ci?i. Aee?eoaaiiy aac caeeoeiaeo ci?i cono??/aeiny ??aeei - 1,35 %. Ia?aae aeieneith oai?eo c? noaoe?iia?o o a?eueoino? i?aee?oe?a a?aei?/aeany iayai?noue o?a?icieo (88,51 %) ? aiaieuaaeo (55,4 %) ci?i ??ciiai nooiaith ae?aaeaiino?. O 10,13 % i?aee?oe?a, ui ciaoiaeeeeny i?ae iaaeyaeii, noi?ioaaeany ooaa?eoeueiia. O iieiaeie niinoa?aaeoaaieo (50,68 %) a?aecia/aeeny ieaa?aeuei? iaoa?oaaiiy, ui a?aeiia?aeaee eieae?caoe?? i?ioeano - i?aeaeieueiai? ? iaae?ano?iaeueii? ieaa?e. O 48,68 % i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue i?ney noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy iaee ae?aaeai? caeeoeia? ci?ie o aeaeyae? ina?aaee?a o?a?ico aai ooaa?eoeueiie o niieo/aii? c o?a?icii ? ieaa?aeueieie iaoa?oaaiiyie. Iaeiaio ae?aaeai? caeeoeia? ci?ie aeyaeyeeny o oai?eo c ia?enoeenno?eoii ? e?oaeei ?io?eueo?aoii, a?eueo ae?aaeai? - i?e eiaoey?iiio ? oia?iaeaeiiio, iaea?eueo cia/i? - i?e eia?o? ? eacaici?e iiaaiii??. Aea/aii aeaye? ia?aiao?e iaoiii?oico ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o 186 i?aee?oe?a ca inoaii? 22 ?iee, ye? aoee oiiaii ?iciiae?eai? ia 3 ia??iaee: c 1973 aei 1977 ?., c 1982 aei 1989 ?., c 1990 aei 1995 ?. Anoaiiaeaii, ui o 70-o? ? 90-o? ?iee ae?a/aoa aeaui /ano?oa (55,2610,8 )% - (56,258,3) % oai??ee ia ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue, ai?ae thiaee. Inoaii?ie ?ieaie c'yaeeany oaiaeaioe?y aei ca?eueoaiiy na?aae i?aee?oe?a oe??? ee?i?/ii? oi?ie iaoeaioe?a i?noa (59,388,07)% oa o/i?a (79,695,69)%. Inoaii?ie ?ieaie aeyaey?oueny oaiaeaioe?y aei a?eueo /anoiai ae?aaiinooaaiiy i?ioean?a, ui oa?aeoa?ecothoueny a?eueoei ia'?iii o?aaeaiiy c i?aaaethaaiiyi aenoaeaoeaiiai eiiiiiaioo ? eacaico; c'yaeeeny oae? ee?i?ei-?aioaaiieia?/i? aa??aioe, ye eia?o (13,110,17)% ? eacaicia iiaaiii?y (3,1312,3) %, ye? o 70-o? ?iee ia ae?aaiinooaaeeny, a?eueo i?ae o 1,5 ?ace ca?eueoeeany e?euee?noue oai?eo c ia?enoeenno?eoii (4,6912,2 )%. O ??ci? ia??iaee /ano ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue o i?aee?oe?a iaeiaeiai /anoi - o eiaeiiai ae?oaiai - noi?iaiaeaeoaaany ?iciaaeii eaaaiaai? oeaieie ? o eiaeiiai i'yoiai - oacith ian?iai?iiy. I?e aiae?c? eieae?caoe?? ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue caeaaeiino? a?ae yeiainue ia??iaeo /ano ia anoaiiaeaii, iino?eii a?aecia/aeany ia?aaaaeia eieae?caoe?y i?ioeano o aa?oi?o aeieyo eaaaiue, iaeiae o 90-o? ?iee ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue ii/aa ae?aaiinooaaoeny o ieaei?e aeie? o 2 ?ace ??aeoa, i?ae o 70-o?. E??i oiai, a inoaii? ?iee o 2 ?ace ca?eueoeeany e?euee?noue oai?eo c aeaia?/iith eieae?caoe??th i?ioeano, ui o 90-o? ?iee niinoa??aaeiny o eiaeiiai aeanyoiai. Inoaii?ie ?ieaie iii?oia oaiaeaioe?y aei ca?eueoaiiy e?eueeino? oai?eo c aino?ei ii/aoeii caoai?thaaiiy (18,4214,65) % - (32,8110,25) %; ?ioieneeaoe?ei? neiioiie o ??ci? ia??iaee /ano cono??/aeeny iaeiaeiai /anoi, iaeiae ?nio? oaiaeaioe?y aei ca?eueoaiiy a?aenioeo oai?eo c iayai?noth oaiia?aoo?ii? ?aaeoe?? ia ii/aoeo oai?iae (28,9513,59) % - (42,199,5) %, ui caea?oueny eia?/iei i?e ii/ano?oaii? i?ioean?a, ye? oa?aeoa?ecothoueny iaoe?i?noth o?aaeaiiy. E?euee?noue oai?eo c a?oaeieie nea?aaie o 90-o? ?iee noaea aeinoia??ii iaioith (57,8910,53) % - (18,7511,27) %, ?0,05, ui, iae?iia??i?oa, iaoiiaeaii iaoaaaeiei a?aeiioaiiyi i?aee?oe?a aei naaa. I?e ni?anoaaeaii? iieaciee?a aiae?co e?ia? oai?eo c aiai??th aoei iaeaea o 2 ?ace a?eueoa o 90-o? ?iee (9,3811,9) % ii??aiyii c 70-ie (5,2615,78) %, aea i?aee?oe?a c eaeeioeeoicii aoei o 2 ?ace iaioa (21,8811,04)% ? (42,1112,34) %, ?0,05, a in?a ?c ca?eueoaiith OIA - o 3 ?ace (20,3212,6) % ? (60,5313,8) %, ?0,05, iaeiae a?aenioie i?aee?oe?a c e?ioioeeoicii o 90-o? ?iee aoa o 9 ?ac?a a?eueoee ii??aiyii c 70-ie (25,010,83)% ? (2,616,0) %, ?0,05, ui aea? ciiao aiai?eoe i?i a?eueo aenieo ?ioiieia?/io ?aaeoeai?noue oai?eo a inoaii? ?iee. I?e ii??aiyii? aeaieo aaeoa??ieia?/iiai aeine?aeaeaiiy iie?ioeiiy anoaiiaeaii oaiaeaioe?th aei a?eueo /anoiai aeyaeaiiy IAO o 90-o? ?iee (32,511,3) % ii??aiyii c 70-ie (23,6813,1) %, ?0,05, ui ocaiaeaeo?oueny c ia?aaaaeaiiyi a?eueo aaaeeeo i?ioean?a o inoaii? ?iee. Aea/aiiy /ooeeaino? aei ooaa?eoe?io iieacaei, ui o 90-o? ?iee ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue o i?aee?oe?a /ano?oa i?ioiaeea ia oii? iii??ii? /ooeeaino? aei ooaa?eoe?io ii??aiyii c 80-ie (85,944,7) % ? (58,87) %, ?0,001, iaeiae a?ia?a?a?/i? ?aaeoe?? o 90-o? ?iee iaee i?noea o eiaeiiai nueiiiai. Niinoa??aa?oueny oaiaeaioe?y aei ciaioaiiy o?eaaeino? noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy:, e?euee?noue oai?eo c o?eaae?noth e?eoaaiiy o noaoe?iia?? 8 - 10 i?nyoe?a o 90-o? ?iee ciaioeeany o 3 ?ace, a c o?eaae?noth e?eoaaiiy a?eueoa 10 i?nyoe?a - o 2 ?ace ii??aiyii c 70-ie ?ieaie, ui iiaeia iiynieoe cia/iith i??ith aaaaeaiiyi aei oe?iei? i?aeoeee oaeeo i?ioeooaa?eoeueicieo i?aia?ao?a, ye ?eoaae?i ? aoaiaooie. AENIIAEE 1. ?io?eueo?aoeaiee ooaa?eoeueic o i?aee?oe?a o iao /an caeia? i?ia?aeia i?noea na?aae ee?i?/ieo oi?i eaaaiaaiai ooaa?eoeueico; eiai ieoiia aaaa na?aae on?o oi?i neeaea 43,5 %. O a?oe? 13 - 15 ?ie?a ae?a/aoa oai??thoue ia oeth oi?io ooaa?eoeueico a?eueo i?ae o 4 ?ace /ano?oa, i?ae thiaee (15,5 % ? 3,4 % a?aeiia?aeii). 2. ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue o i?aee?oe?a oa?aeoa?eco?oueny o a?eueoino? (76,35 %) oai?eo iaoe?i?noth o?aaeaiiy o aeaeyae? oia?iaeaeiiai ?io?eueo?aoo, eia?oo, ia?enoeenno?eoo ? eacaicii? iiaaiii??, iayai?noth ?iciaaeo (50 %) ? aaeoa??iaeae?eaiiyi (46,62 %). O 43 % oai?eo caoai?thaaiiy ?icaeaaeiny ia oii? a??aaeo ooaa?eoe?iiai? ?aaeoe??. 3. ?ioiieia?/ia ?aaeoeai?noue o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue ci?iaia o aeaeyae? i?aeaeuaiiy III, cia/iiai cieaeaiiy ??aiy aeanoiooai?aiiy c PPD, ae?aaeaiiai cieaeaiiy ianiaoeeo?/ii? ?aaeoeaiino? (?AO c OAA, A-?OE, Ig A, Ig M) ? ca?eueoaiiy ??aiy a?noai?io. O i?aee?oe?a c ?iciianthaeaeaieie i?ioeanaie a?aei?/a?oueny cia/ia cieaeaiiy iieaciee?a ianiaoeeo?/ii? ?aaeoeaiino? ii??aiyii c iniaaie, ye? iathoue iaeo ieiuo o?aaeaiiy. Iayai?noue eiioaeoo c oai?eie ia ooaa?eoeueic ? a?ia?a?a?/ia /ooeea?noue aei ooaa?eoe?io o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue noi?iaiaeaeothoueny a?eueo ae?aaeaiei cieaeaiiyi ianiaoeeo?/ii? ?aaeoeaiino?. I?e ?io?eueo?aoeaiiio ooaa?eoeueic? eaaaiue ia a?aei?io a?ae aiaieuaaiai o i?aee?oe?a ia? i?noea a?eueo cia/ia ciaioaiiy ??aiy aeanoiooai?thaaiiy c PPD ? OAA. O i?ioean? iniiaiiai eo?no e?eoaaiiy a?aei?/a?oueny iinooiiaa ii?iae?caoe?y ?ioiieia?/ii? ?aaeoeaiino?, yea iaeneiaeueii a?aeiiaeth?oueny /a?ac 6 i?nyoe?a e?eoaaiiy. 4. O i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue niinoa??aa?oueny ca?eueoaiiy ai?noo OOA (o??aio?iiiiai ai?iiio), O3 (o?eeiaeo??ii?io), O4 (o??ien?io) ? ei?oecieo, ui na?ae/eoue i?i iai?oaeaiee ooieoe?iiaeueiee noai ueoiaeaeii? oa iaaeie?eiaeo caeic ? aeicaiey? oa?aeoa?ecoaaoe aeaiee noai, ye no?an. I?e aiaieuaaiio ooaa?eoeueic? eaaaiue, ia a?aei?io a?ae ?io?eueo?aoeaiiai, ??aaiue ei?oecieo a ii??aiyii? c eiio?ieai ia ci?iaiee. Ia i?ee?ioe? noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy ooieoe?iiaeueiee noai ueoiaeaeii? caeice aeaui iie?aueany, a ai?no ei?oecieo eeoa?oueny cia/ii i?aeaeuaiee, ui a?aeia?aaea? iai?oaeaiiy aaeaioaoe?eieo i?ioean?a, ui caa??aa?oueny. 5. O e?ioe? noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy niinoa??aaeiny caoyaiaiiy ii?iaeiei ?iciaaeo o 98,65 % oai?eo, i?eiaaeoa??? ooaa?eoeueico ia noaee aeyaeyoeny o 98,55 % i?aee?oe?a. O 48,68 oai?eo c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue i?ney e?eoaaiiy o noaoe?iia?? iaee ae?aaeai? caeeoeia? ci?ie o aeaeyae? aiaieu aai ooaa?eoeueiie o niieo/aii? c o?a?icii ? ieaa?aeueieie iaoa?oaaiiyie, ui aea? ciiao aiai?eoe i?i iaiao?aei?noue i?iaaaeaiiy a?eueo ?ioaineaii? ? o?eaaei? o?i?ioa?ai?? o oeueiai eiioeiaaioo c iaia'yceiaei canoinoaaiiyi iaoiaaiaoe/ieo cania?a aeey i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy. 6. ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue o i?aee?oe?a iaeaea o iieiaei? aeiaaee?a (44,59 %) aoei aeyaeaii i?e caa?iaii?; o oeeo oai?eo i?ioean oa?aeoa?ecoaaany iaoe?i?noth o?aaeaiiy o 86,35 % ? oacith ?iciaaeo o 66,6 % aeiaaee?a. Oiio ?aeiiaiaeo?oueny aaeineiiaeaiiy i?aai?caoe?? ? yeino? ?aiiueiai aeyaeaiiy ooaa?eoeueico, a oaeiae i?aeneeaiiy ?iaioe c i?aee?oeaie c ina?aaee?a ooaa?eoeueicii? ?ioaeoe??. 7. Aea/aiiy iaoiii?oico ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a c 1973 aei 1995 ??. aeaei ciiao aeyaeoe, ui inoaii?ie ?ieaie ii/ano?oaee aeiaaeee iaoe?ieo i?ioean?a, c'yaeeeny oae? ee?i?ei-?aioaaiieia?/i? aa??aioe, ye eia?o ? eacaicia iiaaiii?y, ca?eueoeeany e?euee?noue oai?eo c aeaia?/iith eieae?caoe??th i?ioeano; aino?ee ii/aoie caoai?thaaiiy c i?aeaeuaiiyi oaiia?aoo?e niinoa??aaany o 1,5 ?ace /ano?oa o 90-o? ?iee ii??aiyii c 70-ie. I?AEOE*I? ?AEIIAIAeAOe?? 1. C iaoith nai?/aniiai aeyaeaiiy ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a ?aeiiaiaeo?oueny i?aeaeueoe ye?noue i?io?eaeoe/ieo ianoaaeaiue (ooaa?eoe?iiae?aaiinoeee, oethi?ia?ao??), i?iaiaeeoe ?o nai?/anii; iineeeoe eiio?ieue ca ?aaoey?i?noth ianoaaeaiiy i?aee?oe?a c aiaieu ooaa?eoeueicii? ?ioaeoe??, i?e caa?iaii? i?aee?oe?a aei iie?ee?i?ee c? nea?aaie ?ioieneeaoe?eiiai oa?aeoa?o ? a?oaeieie, aei eiiieaeno ianoaaeaiiy iaiao?aeii aeeth/aoe ?aioaaiieia?/iee iaoiae. 2. A ?noi??? oai?iae i?aee?oe?a aaaeaii a?aeoai?thaaoe ee?i?ei-?aioaaiieia?/iee aa??aio ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue, o?aoiaoaaoe iayai?noue ? oa?aeoa? eiioaeoo c oai?eie ia ooaa?eoeueic, nooi?iue ooaa?eoe?iiai? /ooeeaino? aeey aecia/aiiy aaeaeaaoii? oaeoeee aaaeaiiy eiaeiiai oai?iai. 3. Aeey ciaioaiiy e?eueeino? ? ?ici???a caeeoeiaeo ci?i i?ney iniiaiiai eo?no e?eoaaiiy o i?aee?oe?a c ?io?eueo?aoeaiei ooaa?eoeueicii eaaaiue iaiao?aeii canoiniaoaaoe ?ioaineaio aioeaaeoa??aeueio oa?ai?th ? iaoiaaiaoe/i? i?aia?aoe. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1. Nooaiiaa E.A. Iniaaiiinoe eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia a nia?aiaiiuo oneiaeyo // Oe?. ioeueiiiie. aeo?i. - 1997. - ? 4(18). - N. 25 - 27. 2. Nooaiiaa E.A. Eiioiieiae/aneay ?aaeoeaiinoue iiae?inoeia, aieueiuo eioeeueo?aoeaiui ooa?eoeacii eaaeeo // Aanoiee i?iaeai aeieiaee e iaaeeoeeiu. - Iieoaaa; Oa?ueeia. - 1998. - ? 12. - N. 85 - 91. 3. Nooaiiaa E.A. Yooaeoeaiinoue ea/aiey iiae?inoeia, aieueiuo eioeeueo?aoeaiui ooaa?eoeacii eaaeeo // Oe?. ioeueiii. aeo?i. - 1998. - ? 2. - N. 26 - 28. 4. Nooaiiaa E.A. Eeeieei-?aioaaiieiae/aneea aa?eaiou eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia //Oac. aeiee. THaeeaeiie eiioa?aioeee iieiaeuo o/aiuo, iinayuaiiie 70-eaoeth Oa?ueeianeiai einoeoooa oniaa?oainoaiaaiey a?a/ae. - Oa?ueeia, 1993. - N. 95. 5. Ne?aiei E.A., Ia?/aiei I.TH., Nooaiiaa E.A. No?oeoo?a eeeie/aneeo oi?i aeoeaiiai ooaa?eoeaca i?aaiia aeuoaiey o iiae?inoeia // Oac. aeiee. IV nuacae ooeceao?ia Eacaonoaia. - Aeia-Aoa, 1992. - N. 287 - 288. 6. Ne?aiei E.A., Ia?/aiei I.TH., Nooaiiaa E.A. ?aioaaiieiae/aneay oa?aeoa?enoeea eeeie/anee ecea/aiiiai ooaa?eoeaca i?aaiia aeuoaiey o iiae?inoeia // Iaoa??aee Oe?a?inueei? iaoe.-i?aeo. eiio. “I?iiaiaaa ae?aaiinoeea caoai?thaaiue a?oaeii? ee?oee”, i. ss?ai/a ?aaii-O?aie?a. iae. - Ee?a, 1992. - N. 103. 7. Ne?aiei E.A., Nooaiiaa E.A., Nieiaueaaa I.A. ?aioaaiieiae/aneay oa?aeoa?enoeea inoaoi/iuo eciaiaiee iinea eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia //Oace aeii. Oe?a?inueeiai eiia?ano ?aae?ieia?a (Oe?’95). - Ee?a, 1995. - N. 57. 8. Ne?aiei E.A., Ia?/aiei I.TH., Nooaiiaa E.A. ?acoeueoaou iniiaiiai eo?na ea/aiey eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia // Oac. aeiee. “Aeooaeueiua i?iaeaiu ea/aiey e ?aaaeeeoaoeee iiae?inoeia n niiaoe/aneeie e ineoe/aneeie caaieaaaieyie”. - Oa?ueeia, 1995. - N. 110. 9. Ne?aiei E.A., Eoiaeeon A.I., Ei?ieyeiaa A.ss., Nooaiiaa E.A. No?oeoo?a caaieaaaaiinoe ooaa?eoeacii iiae?inoeia //Na. ?acthia ???(O??) Nuacaea iao/ii-iaaeeoeeineie annioeeaoeee ooeceao?ia. - I., 1997. - N. 65. 10. Ne?aiei E.A., Ia?/aiei I.TH., Nooaiiaa E.A. Iaoiii?oic eioeeueo?aoeaiiai ooaa?eoeaca o iiae?inoeia n 1973 ii 1995 aa. //Na. ?acthia ???(O??) Nuacaea iao/ii-iaaeeoeeineie annioeeaoeee ooeceao?ia ??? (O??): Na. ?acthia. - I., 1997. - N. 66. 11. Eeiioaiei TH.O., E?ooueei A.N., Nooaiiaa E.A. ?aioaaiieiae/aneay oa?aeoa?enoeea eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia //Ca. iaoe. ?ia?o Anioe?aoe?? ?aae?ieia?a Oe?a?ie “ I?iiaiaaa ae?aaiinoeea, i?iiaiaaa oa?ai?y”.- Aei. 1. - Ee?a, 1997. - N. 23. Nooaiiaa E. A. Iniaeeaino? ?io?eueo?aoeaiiai ooaa?eoeueico eaaai?a o i?aee?oe?a ca no/anieo oiia. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14. 01. 26 - ooec?ao??y. ?inoeooo ooec?ao??? ? ioeueiiiieia?? ?i. O. A. ssiianueeiai Aeaaeai?? iaaee/ieo iaoe Oe?a?ie, Ee?a, 1999. Iiaeaia aei caoenoo aeena?oaoe?y o aeaeyae? ?oeiieno oa 11 iaoeiaeo ioae?eaoe?e, o yeeo a?aeia?aaeaii iniaeeaino? ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a ca no/anieo oiia ia i?aenoaa? aiae?co caoai?thaaiiy o 186 i?aee?oe?a. C’yniaaii, ui ?io?eueo?aoeaiee ooaa?eoeueic eaaaiue o i?aee?oe?a caeia? i?ia?aeia i?noea na?aae ee?i?/ieo oi?i eaaaiaaiai ooaa?eoeueico ? oa?aeoa?eco?oueny iioe?ai?noth o?aaeaiiy (76,35 %), iayai?noth ?iciaaeo (50 %) ? aaeoa??iaeae?eaiiyi, ci?iith ?ioiieia?/ii? ?aaeoeaiino?. I?ney noaoe?iia?iiai aoaio iniiaiiai eo?no e?eoaaiiy 48,68 % oai?eo iaee ae?aaeai? caeeoeia? ci?ie, ui na?ae/eoue i?i iaiao?aei?noue i?iaaaeaiiy o ieo ?ioaineaii? o?i?ioa?ai??. Aea/aiiy iaoiii?oico ?io?eueo?aoeaiiai ooaa?eoeueico eaaaiue o i?aee?oe?a c 1973 aei 1995 ?ieo aecia/eei ca?eueoaiiy e?eueeino? oai?eo c iioe?aiei o?aaeaiiyi ? aeaia?/iith eieae?caoe??th i?ioeano i?ioyaii inoaii?o ?ie?a. Eeth/ia? neiaa: ?io?eueo?aoeaiee ooaa?eoeueic, i?aee?oee. Sukhanova L. A. Infiltrated tuberculosis of lungs in teenagers under modern circumstances.- Manuscript. Thesis for Candidate of Medical Science degree on speciality 14.01.26 “phtisiology”. Institute of Phtisiology and Pulmonology named by F. G. Yanovsky, Academy Medical Sciences of Ukraine, Kiev, 1999. The thesis in form of manuscript and 11 scientific publications in which peculiarities of infiltrated tuberculosis of lungs under modern circumstances on the basis of 186 teenagers analyses of the disease is represented. It was determined that infiltrated tuberculosis of lungs in teenagers play a leading role among clinical forms of pulmonary tuberculosis and characterized by extensive damage (76,35%), heavy decay (50 %) and discharge of bacteria (46,6 %) change of immune reactivity. After in-patient period of main curative course 48,68 % of patients had manifested changes indicating the necessity of intensive chemotherapy. Study of pathomorphosis of infiltrated pulmonary tuberculosis in teenagers from 1973 to 1995 revealed an increase in number of patients with an extensive lesion and bilateral localization of the process for the latest years. Key words: infiltrated tuberculosis of lungs, teenagers Nooaiiaa E. A. Iniaaiiinoe eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia a nia?aiaiiuo oneiaeyo. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.26 - ooeceao?ey. Einoeooo ooeceao?ee e ioeueiiiieiaee ei. O. A. ssiianeiai Aeaaeaiee iaaeeoeeineeo iaoe Oe?aeiu, Eeaa, 1999. I?aaenoaaeaia e caueoa aeenna?oaoeey a aeaea ?oeiiene e 11 iao/iuo ioaeeeaoeee, a eioi?uo io?aaeaiu iniaaiiinoe eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo a nia?aiaiiuo oneiaeyo ia iniiaaiee aiaeeca caaieaaaiey o 186 iiae?inoeia, 15 aieueiuo i/aaiaui ooaa?eoeacii eaaeeo yaeeenue a?oiiie n?aaiaiey, 39 ia eioeoee?iaaiiuo ooaa?eoeacii ninoaaeee eiio?ieueioth a?oiio, anaai ianeaaeiaaii 240 iiae?inoeia. Ana iiae?inoee ianeaaeiaaeenue n i?eiaiaieai iaycaoaeueiuo, aeiiieieoaeueiuo e oaeoeueoaoeaiuo iaoiaeia aeeaaiinoeee. E?iia oiai, aeey ioeaiee eiioiieiae/aneie ?aaeoeaiinoe i?eiaiyeny eiiieaen iaoiaeia, eioi?ue aeeth/ae ?AO n PPD, ?AO n OAA, A-?IE, enneaaeiaaiea o?iaiy eiioiiaeiaoeeiia A, I, G e niaea?aeaiea aenoaieia a nuai?ioea e?iae. Aeey ii?aaeaeaiey ooieoeeiiaeueiiai ninoiyiey ueoiaeaeiie aeaeacu e iaaeii/a/ieeia enneaaeiaaeinue niaea?aeaiea a ieacia e?iae OOA (oe?aio?iiiiai ai?iiia), O3 (o?eeiaeoe?iieia), O4 (oe?ieneia) e ei?oeciea. Onoaiiaeaii, /oi eioeeueo?aoeaiue ooaa?eoeac eaaeeo o iiae?inoeia caieiaao aaaeouaa ianoi n?aaee eeeie/aneeo oi?i eaai/iiai ooaa?eoeaca; aai oaeaeueiue aan n?aaee anao oi?i ninoaaee 43,5%. A 13-15 eao aeaaooee aieatho yoie oi?iie ooaa?eoeaca aieaa /ai a 4 ?aca /aua, /ai thiioe (15,5% e 3,4% niioaaonoaaiii). Eioeeueo?aoeaiue ooaa?eoeac eaaeeo o iiae?inoeia oa?aeoa?ecoaony o aieueoeinoaa (76,35%) aieueiuo iaoe?iinoueth ii?aaeaiey a aeaea iaeaeiaeaeiiai eioeeueo?aoa, eiaeoa, ia?enoeenno?eoa e eacaiciie iiaaiiiee, iaee/eai ?aniaaea (50%) e aaeoa?eiauaeaeaieai (46,62%). O 43 % aieueiuo caaieaaaiea ?acaeaaeinue ia oiia ae?aaea ooaa?eoeeiiaie ?aaeoeee. ?aioaaiieiae/aneay ea?oeia eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia i?aaenoaaeaia i?ioeannaie i?aeiouanoaaiii a aa?oieo (83,78%), ?aaea a ieaeieo (10,14%) aeieyo eaaeeo, o eaaeaeiai aeaayoiai (11,49%) ii?aaeaiu iaa eaaeeo. Iieeii?oeci ?aioaaiieiae/aneeo i?iyaeaiee aeaiiie eeeie/aneie oi?iu nicaeaao o?oaeiinoe a aeeaaiinoeea ooaa?eoeaca e i?iaaaeaiee aeeooa?aioeeaeueiie aeeaaiinoeee n ianiaoeeoe/aneeie ainiaeeoaeueiuie caaieaaaieyie eaaeeo, iiyoiio 28,38% iiae?inoeia n eioeeueo?aoeaiui ooaa?eoeacii eaaeeo aei iinooieaiey a noaoeeiia? iieo/aee ea/aiea a oa/aiea 2-4 iaaeaeue ianiaoeeoe/aneeie aioeaaeoa?eaeueiuie i?aia?aoaie. Eiioiieiae/aneay ?aaeoeaiinoue o iiae?inoeia n eioeeueo?aoeaiui ooaa?eoeacii eaaeeo eciaiaia a aeaea iiauoaiey III, cia/eoaeueiiai nieaeaiey o?iaiy aeanoiia?aciaaiey n PPD, au?aaeaiiiai nieaeaiey ianiaoeeoe/aneie ?aaeoeaiinoe (?AO n OAA, A-?IE, Ig A, Ig M) e oaaee/aiey o?iaiy aenoaieia. O iiae?inoeia n ?ani?ino?aiaiiuie i?ioeannaie ioia/aaony aieueoaa nieaeaiea iieacaoaeae ianiaoeeoe/aneie ?aaeoeaiinoe ii n?aaiaieth n eeoeaie, eiathueie iaeoth ieiuaaeue ii?aaeaiey. Iaee/ea eiioaeoa n aieueiuie ooaa?eoeacii e aeia?a?ae/aneay /oanoaeoaeueiinoue e ooaa?eoeeio o iiae?inoeia n eioeeueo?aoeaiui ooaa?eoeacii eaaeeo nii?iaiaeaeathony aieaa au?aaeaiiui nieaeaieai ianiaoeeoe/aneie ?aaeoeaiinoe. I?e eioeeueo?aoeaiii ooaa?eoeaca eaaeeo, a ioee/ee io i/aaiaiai, o iiae?inoeia eiaaony aieaa cia/eoaeueiia oiaiueoaiea o?iaiy aeanoiia?aciaaiey n PPD e OAA. A i?ioeanna iniiaiiai eo?na ea/aiey ioia/aaony iinoaiaiiay ii?iaeecaoeey eiioiieiae/aneie ?aaeoeaiinoe, eioi?ay iaeneiaeueii ainnoaiaaeeaaaony /a?ac 6 ianyoeaa ea/aiey. O iiae?inoeia n eioeeueoi?aoeaiui ooaa?eoeacii eaaeeo iaaethaeaaony oaaee/aiea niaea?aeaiey OOA, O3, O4 e ei?oeciea, /oi naeaeaoaeuenoaoao i iai?yaeaiiii ooieoeeiiaeueiii ninoiyiee ueoiaeaeiie aeaeacu, iaaeii/a/ieeia e iicaieyao oa?aeoa?eciaaoue aeaiiia ninoiyiea eae no?ann. I?e i/aaiaii ooaa?eoeaca eaaeeo, a ioee/ee io eioeeueo?aoeaiiai o?iaaiue ei?oeciea a n?aaiaiee n eiio?ieai ia eciaiai, o.a. i?e eioeeueo?aoeaiii ooaa?eoeaca eaaeeo iaaethaeaaony aieaa iai?yaeaiiia ninoiyiea ooieoeee iaaeii/a/ieeia. A eiioea noaoeeiia?iiai yoaia iniiaiiai eo?na ea/aiey ooieoeeiiaeueiia ninoiyiea ueoiaeaeiie aeaeacu ianeieueei oeo/oaaony, a niaea?aeaiea ei?oeciea inoaaony cia/eoaeueii iiauoaiiui , /oi io?aaeaao nio?aiythuaany iai?yaeaiea aaeaioaoeeiiiuo i?ioeannia. I?e auienea ec noaoeeiia?a iaaethaeaeinue cae?uoea iieinoae ?aniaaea o 98,65% aieueiuo, ieeiaaeoa?ee ooaa?eoeaca ia?anoaee ii?aaeaeyoueny o 98,55% iiae?inoeia. O 48,68% aieueiuo n eioeeueo?aoeaiui ooaa?eoeacii eaaeeo iinea ea/aiey a noaoeeiia?a eiaee au?aaeaiiua inoaoi/iua eciaiaiey a aeaea i/aaia eee ooaa?eoeaiu a ni/aoaiee n oea?icii e ieaa?aeueiuie ianeiaieyie, /oi iicaieyao aiai?eoue i iaiaoiaeeiinoe i?iaaaeaiey aieaa eioaineaiie e aeeeoaeueiie oeieioa?aiee o aeaiiiai eiioeiaaioa n iaycaoaeueiui i?eiaiaieai iaoiaaiaoe/aneeo n?aaenoa aeey iiauoaiey yooaeoeaiinoe ea/aiey. Eioeeueo?aoeaiue ooaa?eoeac eaaeeo o iiae?inoeia ii/oe a iieiaeia neo/aaa (44,59%) aue auyaeai i?e ia?auaiee; o aeaiiuo aieueiuo i?ioeann oa?aeoa?eciaaeny iaoe?iinoueth ii?aaeaiey a 86,35% e oacie ?aniaaea a 66,6% neo/aaa. Iiyoiio ?aeiiaiaeoaony niaa?oainoaiaaiea i?aaiecaoeee e ea/anoaa ?aiiaai auyaeaiey ooaa?eoeaca, a oaeaea oneeaiea ?aaiou n iiae?inoeaie ec i/aaia ooaa?eoeaciie eioaeoeee. Eco/aiea iaoiii?oica eioeeueo?aoeaiiai ooaa?eoeaca eaaeeo o iiae?inoeia n 1973 ii 1995 aiaeu iicaieeei auyaeoue, /oi ca iineaaeiaa a?aiy o/anoeeenue neo/ae iaoe?iuo i?ioeannia, iiyaeeenue oaeea eeeieei-?aioaaiieiae/aneea aa?eaiou, eae eiaeo e eacaiciay iiaaiiiey, oaaee/eeinue eiee/anoai aieueiuo n aeaoonoi?iiiae eieaeecaoeeae i?ioeanna; ino?ia ia/aei caaieaaaiey n iiauoaieai oaiia?aoo?u iaaethaeaeinue a 1,5 ?aca /aua a 90-a aiaeu ii n?aaiaieth n 70-ie. Eeth/aaua neiaa: eioeeueo?aoeaiue ooaa?eoeac, iiae?inoee.

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