I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

IAOe?IIAEUeIEE IAAeE*IEE OI?AA?NEOAO

EICEIA NA?A?E IEEIEAEIAE*

OAeE 616.334 + 616.342]-005.1-036.11-035-089

IOe?IEA OAEOI??A ?ECEEO I?E AEAI?? O??O?A?*II? OAEOEEE A OAI?EO C
AINO?IE?IAIOI*EAEIE I?EI?IAeOIAeAIAEUeIEIE AE?ACEAIE

14.01.03 — O??o?a?y

A a o i ? a o a ? a o

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a — 1999

Aeena?oaoe?y ? ?oeiienii

?iaioo aeeiiaii o Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao?

?iai? aeaae. I.I.Aiaiiieueoey.

Iaoeiaee ea??aiee

Aeieoi? iaaee/ieo iaoe, i?ioani? OII?I IAO?I AeIEO?IAE*, Iaoe?iiaeueiee
iaaee/iee oi?aa?neoao ?i. I.I.Aiaiiieueoey IIC Oe?a?ie. caa?aeoaa/
eaoaae?ith oaeoeueoaonueei? o??o?a?? ?2.

Io?oe?ei? iiiiaioe:

Aeaaeai?e IAI oa AII Oe?a?ie, Ieaenaiae? Ieaen?eiae/ Oae?iia, aeieoi?
iaaee/ieo iaoe, i?ioani?, Ee?anueeee iaoeiai-aeine?aeiee ?inoeooo
ee?i?/ii? oa aenia?eiaioaeueii? o??o?a??.

Aeieoi? iaaee/ieo iaoe, i?ioani? NEEAA Aieiaeeie? A?eoi?iae/, caa?aeoaa/
eaoaae?ith o??o?a?/ieo oai?ia Iaaee/iiai ?inoeoooo Oe?a?inueei?
anioe?aoe?? ia?iaeii? iaaeeoeeie.

I?ia?aeia onoaiiaa:

Ee?anueea Iaaee/ia Aeaaeai?y i?neyaeeieiiii? ina?oe IIC Oe?a?ie
?i.I.E.Ooieea, eaoaae?a o??o?a?? c eo?nii oiiia?ao?/ii? aiaoii?? oa
iia?aoeaii? o??o?a??.

Caoeno a?aeaoaeaoueny “ 21 ” o?aaiy 1999 ?. i “ 13-00 ” aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee ii caoenoo aeena?oaoe?e ia
caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe ca niaoe?aeuei?noth
“O??o?a?y” (Ae 26.003.03) i?e Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao?.
(Aae?ana: 252004, i. Ee?a, aoeueaa? Oaa/aiea 17)

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? Iaoe?iiaeueiiai
iaaee/iiai oi?aa?neoaoo ?i.I.I.Aiaiiieueoey. (Aae?ana: 252057,
i.Ee?a-57, aoe. Ciieia?/ia 3)

Aaoi?aoa?ao ?ic?neaiee “ 20 ” ea?oiy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? ?aaee

eaiae. iaae. iaoe, ss.I.A?oianueeee

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie. Iie?auaiiy ?acoeueoao?a e?eoaaiiy oai?eo c
aino?ie?iaioi/eaeie i?ei?iaeoiaeaiaeueieie ae?aceaie (AEIAeA)
caeeoa?oueny aeooaeueiei ieoaiiyi no/anii? o??o?a?? (A.A.Oaeeiia o
niaao., 1989; A.Ae.A?aoonue, 1990; I.I.Aaeeaioeeee o niaao., 1990;
E.E.Aa/aa, 1991; A.O.Caeoeaa e niaao., 1994; D. Lieberman, 1993; K.D.
Fan, 1993). Aeeneon?eieie ? ieoaiiy aeai?o oa?i?io, iaoiaeo iia?aoe??;
iacaaeia?eueieie ? ?acoeueoaoe on?o aeae?a e?eoaaiiy oai?eo c AEIAeA o
?ac? aeieeiaiiy ?aiiueiai ?aoeeaeeao e?iaioa/? (X. Mueller, J.M.
Rothenbuehler, 1994; K.P. Thon, H. Stoltzing, 1995; C. Martinez Ramos,
J.R. Nunez Pena, 1995). ?acaeoe?y oeoiea, ca aeaieie W. Jedrzejczyk oa
ni?aaaoi??a (1989), Ae.Aa?aoaaa oa ni?aaaoi??a (1993), A.Ieoiaa oa
ni?aaaoi??a (1993), B.Millat oa ni?aaaoi??a (1993), aaaaea?oueny
iia?aoe??th aeai?o iacaaaeath/e ia oa, ui noi?iaiaeaeo?oueny
eaoaeuei?noth ia aenio? e?iaioa/? a?ae 40-50% aei 95% (M.Lombardi oa
ni?aaao., 1985; G.Jatzko oa ni?aaao., 1993).

?aii?e ?aoeeaeea ae?aceiai? e?iaioa/? (??AE), ca aeaieie A.A.
Oa?aaa?thoa (1994), C. Villanueva (1993), J.L. Jaramillo (1994), S.
Loperfido (1994), C. Ell, F. Hagenmuller (1995), O. Caputi Iambrenghi
(1995), ui aeieea? a 15-38% aeiaaee?a, ca?eueoo? ia?aeiio e?iaiao?aoo,
iiaeeaeth? ii?ooaiiy aiiainoaco oa i?e?ioee?eoeyoe??, /ei coiiaeth?
iia??oaiiy oiia aeey aoaeue-yeiai aeaeo aeno?aiiai o??o?a?/iiai
ao?o/aiiy. O ca’yceo c oeei i?iaiicoaaiiy ??AE o oai?eo c
aino?ie?iaioi/eaeie i?ei?iaeoiaeaiaeueieie ae?aceaie ? aeooaeueiei o
aeai?? ?aoe?iiaeueii? o??o?a?/ii? oaeoeee.

O o??o?a?/i?e i?aeoeoe? oni?oii ?ic?iaeythoueny oa aeei?enoiaothoueny
no/ani? iaoaiaoe/i? iaoiaee ee?i?/iiai i?iaiicoaaiiy (I.I. Ieioea?,
1983; A.O.Ae?i, 1997; M.Morosini,1983; Shiu-Kum Lam,1983).
Aaaaoioaeoi?iee aiae?c ee?i?/ieo aeaieo c iaoith aeyaeaiiy oaeoi??a
?eceeo aeieeiaiiy ??AE oa ioe?iea aoaeoeaiino? ??cieo aeae?a iia?aoeaieo
ao?o/aiue noaiiaeoue aaeeeee iaoeiaee oa i?aeoe/iee ?ioa?an (A.A.
Oaeeiia e niaao., 1989; A.Ae. A?aoonue, I.Ae. Oii?i oa ni?aaao.,1997).

Ca’ycie oaie c ieaiii iaoeiaeo i?aoeue onoaiiae. Aeena?oaoe?eia ?iaioa ?
o?aaiaioii eiiieaenii? IAe?: “Aea/eoe aieea oaeoi??a ?eceeo a
iaa?aeeeaaei?e o??o?a?? ae?aceiai? oai?iae ia aaciina?aaei? oa
a?aeaeaeai? ?acoeueoaoe, ?ic?iaeoe aeai?eoie ae?aaiinoeee, e?eoaaiiy oa
i?io?eaeoeee i?neyiia?aoe?eieo oneeaaeiaiue”, ui aeeiioaaeanue ca ieaiii
IIC Oe?a?ie o Iaoe?iiaeueiiio iaaee/iiio oi?aa?neoao? ?iai?
I.I.Aiaiiieueoey, ? aea?ae?a?no?aoe?? 01964004713.

Iniiaia iaoa aeine?aeaeaiiy. I?iaiae?coaaoe oaeoi?e ?eceeo iia?aoeaiiai
e?eoaaiiy ? ?ic?iaeoe aeai?eoi aeai?o o??o?a?/ii? oaeoeee i?e
e?iaioi/eaeo i?ei?iaeoiaeaiaeueieo ae?aceao aeey iie?auaiiy ?acoeueoao?a
e?eoaaiiy oai?eo.

Aeey aeinyaiaiiy oe??? iaoe iio??aii aoei ae??oeoe oae? caaaeaiiy:

1. I?iaiae?coaaoe ??ciiiai?oi? aeaee iia?aoeaieo ao?o/aiue oa
aeno?ai?noue ?o aeeiiaiiy ye oaeoi?e ?eceeo, ui aieeaathoue ia
?acoeueoaoe e?eoaaiiy.

2. Aea/eoe /anoioo oa oa?i?i aeieeiaiiy ??AE ca aeiiiiiaith
aaaaoioaeoi?iiai aiae?co ee?i?/ieo, aaiiaeeiai?/ieo, aiaeineii?/ieo,
eaai?aoi?ieo aeaieo o oai?eo c AEIAeA.

3. ?ic?iaeoe iaoiae i?iaiicoaaiiy eiia??iino? ?icaeoeo ??AE oa aeae?eeoe
a?oie oai?eo c ??ciei nooiaiai ?eceeo eiai aeieeiaiiy.

4. ?ic?iaeoe aeai?eoi aeai?o o??o?a?/ii? oaeoeee o oai?eo c AEIAeA.

Iaoeiaa iiaecia. Iaea?aeaii iia? aeai? uiaei ?eceeo ??cieo aeae?a
iia?aoeaiiai ao?o/aiiy oa aeno?aiino? ?o aeeiiaiiy o oai?eo c AEIAeA.
Aea/aii /anoioo, oa?i?i aeieeiaiiy ??AE oa oaeoi?e, ui ia ieo
aieeaathoue. ?ic?iaeaii eiii’thoa?io i?ia?aio aaoiiaoeciaaiiai
ia/eneaiiy eiia??iino? aeieeiaiiy ??AE oa iaoiae eiai i?iaiicoaaiiy ca
aeiiiiiaith yeiai aia?oa aeae?eaii 3 a?oie oai?eo, ye? iathoue iaeee
(aei 5%), na?aaei?e (50-60%) oa aenieee (85-95%) nooi?iue ?eceeo
aeieeiaiiy ??AE. ?ic?iaeaii iiaee “Niin?a o??o?a?/iiai e?eoaaiiy
e?iaioi/eaeo iaaeieinini/eiaeo ae?acie aeaaiaaeoeyoeiaei? eeoee”, ia
yeee io?eiaii iaoaio Oe?a?ie ? 22940A. Cai?iiiiiaaii aeai?eoi
o??o?a?/ii? oaeoeee, yeee aeicaiey? ciaioeoe e?euee?noue iia?iaaieo
oai?eo ia aenio? ?aoeeaeeao e?iaioa/? a 4,8 ?aco, ?icoe?eoe ae?aiacii
i?aaiicaa??aath/eo ?aaeeeaeueieo iia?aoe?e (ICI) ca ?aooiie ciaioaiiy
e?eueeino? ?acaeoe?e oeoieo (?O) — a 3,2 ?aco.

I?aeoe/ia cia/aiiy ?iaioe. Cai?iiiiiaaiee iaoiae i?iaiicoaaiiy
eiia??iino? aeieeiaiiy ??AE oa aeae?eaiiy o?ueio a?oi iaoe??io?a ca
nooiaiai ?eceeo aeicaiey? aeeoa?aioe?thaaoe aeaee iia?aoeaiiai
ao?o/aiiy ia aeno?ai? (AI) o ?ac? i?iaeiaaeaiiy e?iaioa/?;
iaa?aeeeaaei?, ui aeeiiothoueny i?ioyaii 12-24 aiae o oai?eo c na?aaei?i
oa 6-12 aiae o oai?eo c aenieei ?eceeii ?aoeeaeeao ae?aceiai? e?iaioa/?;
?aii? a?aeno?i/ai? — /a?ac 1-4 aeiae o oai?eo c iaeei ?eceeii oa
noaa?eueiei aaiinoacii. Aeeiiaiiy i?aaiicaa??aath/eo iia?aoe?e iia’ycaia
c iaioei ?eceeii ?icaeoeo oneeaaeiaiue. O?aooaaiiy oaeoi??a ?eceeo
??cieo aeae?a iia?aoeaieo ao?o/aiue oa oa?i?i?a ?o aeeiiaiiy aeicaiey?
iie?aueoe ?acoeueoaoe e?eoaaiiy oai?eo ca ?aooiie ciaioaiiy e?eueeino?
i?neyiia?aoe?eieo oneeaaeiaiue. Aioo??oiueiai?oaeueiee oeyo aaaaeaiiy
?iooc?eieo na?aaeiaeu o oai?eo c yaeuaie aaii?aa?/iiai oieo ni?ey?
cieaeaiith e?eueeino? i?neyiia?aoe?eieo eaaaiaaeo oneeaaeiaiue.

Ai?iaaaeaeaiiy ?acoeueoao?a ?iaioe a i?aeoeeo. ?acoeueoaoe i?iaaaeaieo
aeine?aeaeaiue ai?iaaaeaeai? a i?aeoeeo ?iaioe Ee?anueeiai i?nueeiai
oeaio?o iaa?aeeeaaeii? aeiiiiiae oai?ei c aino?eie oeoieiai-eeoeiaeie
e?iaioa/aie ia aac? o??o?a?/iiai a?aeae?eaiiy i?nueei? ee?i?/ii?
e?ea?i? ?12, e?ea?i? oaeaeei? aeiiiiiae III “Iaaeeoeeia eaoano?io”
i.Ee?a, iaeanii? e?ea?i? i.Oa?iiiiey, e?ea?i? i.Ioea/aaa,
canoiniaothoueny o iaa/aeueiiio i?ioean? ia eaoaae?ao o??o?a?? IIO ?i.
I.I.Aiaiiieueoey. Ca caaaeaiiyi I?i?noa?noaa c iaoee oa iaoeiaeo
oaoiieia?e iaoa??aee aeniiioaaeeny ia aenoaaoe? a Eaa?iao? i?i?no??a
Oe?a?ie (1997), aenoaaoe? “Oe?a?ia nueiaiaei?” IAOe Oe?a?ie (1998).

Iniaenoee aianie aeena?oaioa. Aeena?oaio iniaenoi ?ic?iaea aaco aeaieo
oai?eo c AEIAeA oa cae?eniea noaoenoe/io ia?iaeo, ?ic?iaea nenoaio
i?iaiicoaaiiy ??AE, i?ia?a ?? ?ao?iniaeoeaio oa ee?i?/io ai?iaaoe?th.
?ic?iaeaii eiii’thoa?io i?ia?aio aeey aaoiiaoeciaaiiai ia/eneaiiy
a??ia?aeiino? aeieeiaiiy ??AE. Cai?iiiiiaaii aeai?eoi aeai?o
?aoe?iiaeueii? o??o?a?/ii? oaeoeee o oai?eo c AEIAeA c o?aooaaiiyi
oaeoi??a ?eceeo ??AE oa aeno?aiino? aeeiiaiiy ??cieo aeae?a iia?aoeaieo
ao?o/aiue oa i?iaaaeaii ia?aa??eo eiai aoaeoeaiino?. Aaoi? i?eeiaa
aaciina?aaeith o/anoue o aeeiiaii? o??o?a?/ieo ao?o/aiue oa a
i?neyiia?aoe?eiiio e?eoaaii? oai?eo c AEIAeA.

Ai?iaaoe?y ?iaioe. Iaoa??aee aeena?oaoe?? aeeeaaeai? oa iaaiai?ai? ia:
iaoeiai-i?aeoe/i?e eiioa?aioe?? “Aeooaeuei? i?iaeaie iaaeaiiy
aeno?aiii? aeiiiiiae i?e iaa?aeeeaaeieo noaiao” (Ee?a,1995);
?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?ai?? “Oe?o?ae/aneia ea/aiea
?aoeeaeeae?othueo aano?iaeoiaeaiaeueiuo yca e eo
ineiaeiaiee”(Ee?a,1995); 4th, 5th International Congress of
International Wound Assosiation (Tel-Aviv,1996,1998); ?anioae?eainuee?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? “Aeooaeuei? i?iaeaie iaa?aeeeaaeii?
o??o?a?? i?aai?a /a?aaii? ii?iaeieie oa o?iaai?oaeueiiai o?aeoo”
(Ee?a,1996); ?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?aioe??
“Aeeaaiinoeea e oe?o?ae/aneia ea/aiea caaieaaaiee e iia?aaeaeaiee
aiaia/aii/iuo aeae/iuo i?ioieia” (Ee?a,1996); ?anioae?eainuee?e
eiioa?aioe?? “Iiaua oaoiieiaee a oe?o?aee”; Al VIII-lea Congres de
chirurgie din Republica Moldova (Chisinau,1997), ?anioae?eainuee?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? “Aeooaeueiua aii?inu iaioeiaeiie
oe?o?aee i?aaiia a?thoiie iieinoe” (Oa?e?a,1998), II eiia?an? o??o?a?a
Oe?a?ie (Ee?a-Aeiiaoeuee,1998); can?aeaii? ai?iaaoe?eii? ?aaee
“Caaaeuei? ieoaiiy o??o?a??” IIO.

Ioae?eaoe?? ?acoeueoao?a aeine?aeaeaiiy. Ca oaiith aeena?oaoe??
iioae?eiaaii 26 ?ia?o o iaoeiaeo aeaeaiiyo, a oiio /ene? — 3 noaoo? o
aeo?iaeao, ?aeiiaiaeiaaieo AAE Oe?a?ie, 22 — o a?aeiieo a?o/eciyieo oa
?iicaiieo aeaeaiiyo, aeaeaii 1 ?ioi?iaoe?eiee eeno, iaea?aeaii iaoaio ia
aeiao?ae.

Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 142 noi??ieao
iaoeiiieniiai oaenoo ? neeaaea?oueny ?c anooio, ?icae?eo “Iaoa??aee ?
iaoiaee”, 3 ?icae?e?a aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiae?a,
i?aeoe/ieo ?aeiiaiaeaoe?e oa nieneo e?oa?aoo?e, ui ai?uo? 300 aeaea?ae,
?c ieo 102 — a?o/eciyieo ? 198 — ca?oa?aeieo. ?iaioa ?ethno?iaaia 3
iaethieaie ? 35 oaaeeoeyie.

CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy. A iniiao ?iaioe iieeaaeai?
?acoeueoaoe ae?aaiinoeee oa e?eoaaiiy 573 oai?eo c AEIAeA, yeei a
ia?aae- oa i?neyiia?aoe?eiee ia??iae aoei i?iaaaeaii 931
o?a?iaano?iaeoiaeaiineii?th c aeei?enoaiiyi ca iaiao?aeiino?
aiaeineii?/ieo cania?a aaiinoaco ie?aeiooai?thaaeueieie iie?ia?aie, 9268
caaaeueiiee?i?/ieo eaai?aoi?ieo aeine?aeaeaiue, 2310 aeine?aeaeaiue
nenoaie aaiinoaco, 3616 a?io?i?/ieo aeine?aeaeaiue, 3969 aeine?aeaeaiue
aaiiaeeiai?/ieo iieaciee?a (nenoie?/iee a?oa??aeueiee oene,
ae?anoie?/iee, ioeueniaee, na?aaei?e, oeaio?aeueiee aaiiciee oene,
oieiaee ?iaeaen (Allgover), ??ci? aeaee o??o?a?/iiai ao?o/aiiy o 364
iaoe??io?a c oa?aeoa?enoeeith ?io?aiia?aoe?eieo aeaieo; ioe?ithaaee
/anoioo oa oa?aeoa? i?neyiia?aoe?eieo oneeaaeiaiue, i?e/eie
eaoaeueiino?; i?ia?aie ?iooc?eii-o?ainooc?eii? oa?ai??.

Ianya e?iaiao?aoe ioe?ithaaee ca aeao?oeeoii oee?eoethth/i? e?ia? ca
aeiiiiiaith “?iaeeeaoi?a AeOeE” o??ie “R&C” (Naia?a, ?O). Nooi?iue
aaaeeino? e?iaioa/? aecia/aee ca?aeii c eeaneo?eaoe??th A.Ae.A?aoony
(1989). Aeai? eiaeiiai oai?iai o oi?iae?ciaaiiio aeaeyae? aoee
caianai? aei ?ic?iaeaii? eiiithoa?ii? niaoe?ae?ciaaii? aace aeaieo,
noai?aii? ia iniia? i?ia?aie EXCEL 5 (Microsoft Office). Io?eiai?
oeeo?ia? aeai? ii?aoeueiaai? noaoenoe/ii c aeei?enoaiiyi iaoiae?a
ia?iaee na?aaei?o cia/aiue (Student) oa a?aeiinieo iieaciee?a (Fisher)
(Ae.A.Naiaoeeaa, 1968; A.A.Aoaea?, 1978; I.I.Ieioea? n niaao., 1991) ia
IAII IBM PC AT 586 (iaeao noaoenoe/iiai aiae?co i?ia?ai EXCEL 5 oa EXCEL
7 Microsoft Office).

Aaaaoioaeoi?iee aiae?c noai?aii? aace aeaieo i?iaaaeaii ca iaoiaeeeith
iie?ieiaiai aeene?ei?iaioiiai aiae?co (Aeae.-I.Eei e niaao., 1989)
iaeaoo noaoenoe/iiai aiae?co SAS (SAS Institute Inc., 1987). sse
iaoaiaoe/ia iiaeaeue aeei?enoaia e?i?eia aeene?ei?iaioia ooieoe?y aeaeo:

Fkm= u1X1km+u2X2km+ … + u?X?km + const, (1)

aea Fkm — cia/aiiy aeene?ei?iaioii? ooieoe?? aeey m-ai ia’?eoo a a?oi?
k; Xikm — cia/aiiy aeene?ei?iaioii? ci?iii? O? aeey m-ai ia’?eoo a
a?oi? k; ui — eiao?oe??ioe cia/ouino?.

Aeine?aeaeaiiy i?iaiaeeee a o?ueio iai?yieao:

1. Aiae?c oaeoi??a ?eceeo ??cieo aeae?a aeno?aieo oa ?aii?o
a?aeno?i/aieo o??o?a?/ieo ao?o/aiue o 234 iia?iaaieo oai?eo c
aeine?aeaeaiiyi aeyaeaieo i?neyiia?aoe?eieo oneeaaeiaiue.

2. Iiooe oaeoi??a ?eceeo oa ?ic?iaeo nenoaie i?iaiicoaaiiy ??AE
i?iaiaeeee ia aac? aeaieo 354 oai?eo “iaa/aeueii?” aea??ee oa i?iaaaeaii
?? ioe?ieo o 69 oai?eo, ye? neeaee “aecaiaiaoe?eio” aea??eo.

3. ?ic?iaea oa ai?iaaaeaeaiiy aeai?eoio iioei?caoe?? o??o?a?/ii?
oaeoeee c o?aooaaiiyi nooiaiy ?eceeo ??AE o 130 oai?eo.

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy. Ia?aiao?aie ii??aiyeueiiai
aiae?co aaciina?aaei?o ?acoeueoao?a oa aeyaeaiiy oaeoi??a ?eceeo i?e
aeeiiaii? ??cieo aeae?a aeno?aieo ? ?aii?o a?aeno?i/aieo iia?aoeaieo
ao?o/aiue c i?eaiaeo AEIAeA aoee ia?ai?: a) iaoneeaaeiaiee ia?aa?a
i?neyiia?aoe?eiiai ia??iaeo; a) oneeaaeiaiee ia?aa?a i?neyiia?aoe?eiiai
ia??iaeo oa i?neyiia?aoe?eia eaoaeuei?noue.

A?aeiia?aeii c aeuacacia/aiei 234 i?iiia?iaaieo oai?eo aoee ?iciiae?eai?
ia 2 a?oie: a?oia A — 197 iaoe??io?a (84,2%), ye? ia iaee oneeaaeiaiue a
i?neyiia?aoe?eiee ia??iae, a?oia A — 37 iaoe??io?a (15,8%) c
oneeaaeiaiei (onueiai 89 oneeaaeiaiue, c ieo 52, iia’ycaieo c
oa?aeoa?ii iia?aoeaiiai ao?o/aiiy, ? 37, ia iia’ycaieo c iei) ia?aa?aii
i?neyiia?aoe?eiiai ia??iaeo. A oe?e a?oi? aoee aeae?eai? 2 i?aea?oie:
i?aea?oia A1 — oai?? c oneeaaeiaiiyie i?neyiia?aoe?eiiai ia??iaeo, ui ia
i?ecaiaeeee aei eaoaeueiiai ?acoeueoaoo (26 iaoe??io?a — 11,1%),
i?aea?oia A2 — oai?? c oneeaaeiaiiyie i?neyiia?aoe?eiiai ia??iaeo, ui
i?ecaiaeeee aei eaoaeueieo iane?aee?a (11 iaoe??io?a — 4,7%). O
?acoeueoao? i?iaaaeaiiai aiae?co aeyaeai? iniiai? oaeoi?e, ye?
i?aeaeuothoue ?ecee aeieeiaiiy i?neyiia?aoe?eieo oneeaaeiaiue oa
eaoaeueiino? (oaae. 1).

Oaaeeoey 1. Oaeoi?e ?eceeo aeieeiaiiy i?neyiia?aoe?eieo oneeaaeiaiue

Oaeoi?eA?oia oai?eo aac oneeaaeiaiue (a?oia A)A?oia oai?eo c
oneeaaeiaiiyie

(a?oia A) AA1+A2A21.AENO?AI?NOUe IIA?AOe??- Aeno?ai? (n=103)78 (75,7%)

25 (24,3%)9 (8,7%)

-?aii? a?aeno?i/ai? (n=131) 119 (90,9%)*

12 (9,1%)*2 (1,5%)*

2.AEAeE IIA?AOe?E 1 -?acaeoe?? oeoiea (n=47)25 (53,2%)22 (46,8%)7
(14,9%)

-I?aaiicaa??aath/? (n=185)172 (93,0%)***13 (7%)*** 7,0%)***2 (1,1%)**

3.NOOI?IUe E?IAIOA*?: — Iii??iee (n=97)91 (93,8%)6 (6,2%)0

— Na?aaei?e (n=64)54 (84,4%)*10(15,6%)*3 (4,7%)*

— Aaaeeee (n=73)52 (71,2%)*21(28,8%)*8(11%)*

6%)**

4. A?E OAI?EO — Aei 40 ?ie?a (n=52)50 (96.2%)2 (3,8%)0

-A?ae 40 aei 60 ?ie?a (n=116)107 (92,2%)9 (7,8%)2 (1,7%)*

-Noa?oeo ca 60 ?ie?a (n=66)40 (60,6%)*26(39,4%)*9 (13,6%)**

I?ei?oee: 1- aac o?aooaaiiy ia?aaeeeaeueieo ao?o/aiue, *- ?<0.05, **- ?<0.01, ***- ?<0.001. Oaeei /eiii, iiiioaeoi?iee aiae?c ?eceeo o??o?a?/iiai e?eoaaiiy iieaco?, ui o ?ac? aeeiiaiiy aeno?aieo iia?aoe?e ia aenio? e?iaioa/? i?neyiia?aoe?ei? oneeaaeiaiiy aeieeathoue o 2,7 ?ace /ano?oa, a ??aaiue eaoaeueiino? o 5,9 ?aco aeuee, i?ae o ?ac? ?aii?o a?aeno?i/aieo. A naith /a?ao, ?acaeoe?ei? iaoiaee i?aeaeuothoue ?ecee iani?eyoeeaeo iane?aee?a o 5,8 ?aco oa eaoaeuei?noue - o 6,5 ?aco. ?acoeueoaoe iia?aoeaiiai e?eoaaiiy aecia/athoue oaeiae ? nooi?iue e?iaioa/?. I?neyiia?aoe?ei? oneeaaeiaiiy o ?ac? aaeeei? e?iaiao?aoe iaee i?noea a 2 ?ace /ano?oa, i?ae i?e na?aaeiueiio ? a 4,6 ?aco /ano?oa, i?ae i?e iii??iiio nooiai?; i?e oeueiio ??aaiue eaoaeueiino? c?inoaa c 0% i?e iii??iiio nooiai? aei 10,9% i?e aaaeeiio. A?e iia?iaaieo oai?eo oaeiae ? nooo?aei oaeoi?ii ?eceeo, ine?eueee /anoioa ?icaeoeo i?neyiia?aoe?eieo oneeaaeiaiue c?inoa? o 10,4 ?aco, a ??aaiue eaoaeueiino? - o 8 ?ac?a o iaoe??io?a o a?oe? noa?oeo ca 60 ?ie?a ii??aiyii c a?oiith iia?iaaieo o a?oe? aei 60 ?ie?a. Io?eiai? aeai? iathoue aaaeeeaa iaoeiai-i?aeoe/ia cia/aiiy a ieai? ?ic?iaee, iaa?oiooaaiiy oa iiooeo ?aca?a?a iie?auaiiy ?acoeueoao?a o??o?a?/iiai e?eoaaiiy oai?eo c AEIAeA. I?e aeaoaeueiiio aiae?c? iia?aoeaiiai e?eoaaiiy oai?eo c AEIAeA aoei anoaiiaeaii, ui a no?oeoo?? aeno?aieo iia?aoe?e a?eueoa 80% neeaaeaee iia?aoe??, ye? aeeiioaaeeny ia aenio? ??AE, ui iaa i?noea ia aeiaini?oaeueiiio aoai? aai a oiiaao noaoe?iia?o. Ine?eueee eiaeiee ianooiiee ?aoeeaeea a oiiaao ii?ooaiue aiiainoaco, ni?e/eiaieo ia?aeiiith e?iaiao?aoith, i?ecaiaeeoue aei ?o iiaeeaeaiiy, ceaio iaoai?ci?a ?aaoeyoe?? oa eiiiainaoe??, iia??oo? noai oai?iai oa oiiae aeeiiaiiy aoaeue-yeiai aeaeo aeno?aiiai o??o?a?/iiai ao?o/aiiy, ie ae??oeee ?ic?iaeoe iaoiae i?iaiicoaaiiy oa iiia?aaeaeaiiy oeueiai aaaeeiai oneeaaeiaiiy. ?ic?iaeo iaoiaeo i?iaiicoaaiiy ??AE i?iaiaeeee o o?e aoaie. Ia ia?oiio aoai? aeai? 80 oai?eo c ?aii?i ?aoeeaeeaii ae?aceiai? e?iaioa/? oa a?oie ii??aiyiiy, yeo neeaee 274 oai?eo aac ?aoeeaeeao e?iaioa/?, aoee aianai? aei “iaa/aeueii?” aea??ee. Aiie aoee oi?iae?ciaai? aeey iiaeaeueoi? iaoaiaoe/ii? ia?iaee. I?ae /an i?iaaaeaiiy iiiioaeoi?iiai aiae?co iaie, ye ? ?ioeie aaoi?aie (Ae?i A.O., 1997; Caoaaao?i E.E. e niaao., 1997), aoei aeyaeaii, ui ia /anoioo aeieeiaiiy ??AE iaea?eueoee aieea iathoue eieae?caoe?y oa iioe?ai?noue ae?aceiai? aeano?oeoe??, noai ia?aeiiiai aaiinoaco, a oaeiae nooi?iue e?iaioa/? oa a?e iaoe??ioa. Ianooiiei aoaiii iaoeo aeine?aeaeaiue aoea ?ic?iaea i?iaiinoe/ii? nenoaie, a ye?e aoa ae a?aeia?aaeaiee aca?iicaycie iaea?eueo ?ioi?iaoeaieo iciae-oaeoi??a ?eceeo ??AE. Ca aeiiiiiaith iie?ieiaiai aeene?ei?iaioiiai aiae?co c iaeaoo i?ia?ai noaoenoe/ii? ia?iaee “SAS” i?iaaaeaia aeine?aeaeaiiy 354 oai?eo “iaa/aeueii?” aea??ee ii aeyaeaiith noeoiiino? oa aca?iiae?? ?ic??cithaaeueieo oaeoi??a na?aae 120 iieaciee?a, ui i?aaenoaaeyee aiaiianoe/i?, ee?i?/i?, aiaeineii?/i?, eaai?aoi?i?, ?io?aiia?aoe?ei? aeai?. O ?acoeueoao? i?iaaaeaii? iaoaiaoe/ii? ia?iaee noai?aii? aace aeaieo aoee aeyaeai? 4 aeene?ei?iaioi? ci?ii? (X1-?ici?? ae?acee; X2-noai aaiinoaco o ae?acoe?; X3- nooi?iue aaaeeino? e?iaioa/?; X4-a?e iaoe??ioa), ye? aeicaieeee ?c caaeaiith a??ia?aei?noth (?0,05) aeeiiaoe ?iciiae?e oai?eo ia aea? a?oie ? ye? iaee iaeaeuo i?iaiinoe/io oe?ii?noue. Aeene?ei?iaioi? ci?ii? oa ?o oeeo?ia? cia/aiiy i?aaenoaaeai? a oaae.2. Oaaeeoey 2. Oa?aeoa?enoeea aeene?ei?iaioieo ci?iieo Aeene?ei?iaioia ci?iiaCia/aiiy aeene?ei?iaioii? ci?iii?1. ?ici?? ae?acee (X1)O1 = 1, ae?acea aei 1 niO1 = 2, ae?acea 1,1-2 niO1 = 3, ae?acea >2 ni2. Noai aaiinoaco o ae?acoe? (X2)O2 = 1, aeii ae?acee
ae?eoi o?a?eiiiO2 = 2, ia aei? ae?acee iaea o?iiaiaaia noaeeia O2 = 3,
ia aei? ae?acee aaeeea o?iiaiaaia noaeeiaO2 = 4, ia aei? ae?acee
cai?oie e?ia? 3. Nooi?iue e?iaioa/? (X3)O3 = 1, iii??ieeO3 = 2
na?aaei?e O3 = 3, aaaeeee4. A?e oai?iai (O4)O4 = 1, a?e < 60 ?ie?a O4 = 2, a?e 60 ?ie?a ?ecee ??AE i?aeaeuoaaany o ?ac? ca?eueoaiiy oeeo?iaiai cia/aiiy aeene?ei?iaioieo ci?iieo. Iaoiaeeea iie?ieiaiai aeene?ei?iaioiiai aiae?co aeicaieeea ia/eneeoe eiao?oe??ioe aeey aeene?ei?iaioieo ci?iieo aeey eiaeii? a?oie (oaae. 3). Oaaeeoey 3. Eiao?oe?aioe aeene?ei?iaioieo ci?iieo oa cia/aiiy eiinoaio. Aeene?ei?iaioia ci?iiaEiao?oe??io E iaaeieeiaiiy ??AEaeieeiaiiy ??AE1. ?ici?? ae?acee (X1)2,995,982. Noai aaiinoaco o ae?acoe? (X2)3,695,783. Aaaee?noue e?iaioa/? (X3)2,183,084. A?e (X4)4,86,05 Eiinoaioa-9,4-23,4 I?ney i?aenoaiiaee oeeo?iaeo cia/aiue aeene?ei?iaioieo ci?iieo, ?o eiao?oe??io?a oa eiinoaio o oi?ioeo (1) io?eio?ii aeey oai?eo aac ??AE ??aiyiiy aeene?ei?iaioii? ooieoe?? (F0) aeaeo: F0=2,99X1+3,69X2+2,18X3+4,8X4 - 9,4 (2) oa aeey oai?eo, ye? iaee ??AE (F1): F1=5,98X1+5,78X2+3,08X3+6,05X4 - 23,4 (3) . Ia iniia? canoinoaaiiy aeaio ??aiyiue ooieoe?e F0 ? F1 o eiaeiiai oai?iai on??? “iaa/aeueii?” aea??ee oa ia/eneaiiy cia/aiue ??cieoe? F=F1-F0 iaie anoaiiaeaii, ui o 72 (90%) oai?eo ?c 80 c ??AE F1 i?e na?aaeiueiio cia/aii? F=2,610,31, oiae? ye na?aae iaoe??io?a, ye? ia iaee ??AE, oaea cia/aiiy F1 aeyaeeinue eeoa o 38 (13,9%) ?c 274 oai?eo i?e na?aaei?e aaee/ei? F=-1,250,14. Oaea aeniea noaoenoe/ia a??ia?aei?noue (?<0,001) ??cieoeue F a a?oiao, ui i?aeeyaaee aiae?co oa aeyaeaia caeaaei?noue /anoioe ??AE a?ae cia/aiue F a “iaa/aeuei?e” aeai?oe? (n=354) noaee iniiaith aeey ?ic?iaee i?iaiinoe/ii? nenoaie ??AE. Iaoaiaoe/ia eiia??i?noue aeieeiaiiy ??AE ?ic?aoiaoaaee ca oi?ioeith: ?(o)=1/ e -X+ e0 , (4) aea ? - ?iia??i?noue , X=(F)=F1- F0 , a=2,71, Cia/aiiy ?(o) o a “iaa/aeuei?e” aea??oe? iiai?noth ei?aethaaee ?c cia/aiiyie F oa na?ae/eee, ui ?c ca?eueoaiiyi cia/aiue aaee/ei F ? ?(o) c?inoa? ? /anoioa ??AE. Ia iniia? io?eiaieo ??cieo oeeo?iaeo cia/aiue F ? ?(o) oa a?aeiia?aeieo ?i /anoio ??AE oai?? “iaa/aeueii?” aeai?ee aoee ?iciiae?eai? ia 3 a?oie ca nooiaiai ?eceeo oa /anoioith aeieeiaiiy ?aoeeaeeao (oaae. 4). A?ao?/iee ae?ac ?iciiae?eo i?eaaaeaii ia ?en.1 Oaaeeoey 4. A?oie ?eceeo aeieeiaiiy ??AE?ecee ??AECia/aiiyE?euee?noue oai?eoF?(o)c ??AE (%)aac ??AE (%)1.Iaeee< 1aei 0,7314 (5,6%)236 (94,4%)2. Na?aaei?ea?ae 1 aei 30,73 - 0,9517 (34,7%)**32 (65,3%)**3. Aenieee> 3> 0,9549 (89,1%)**6
(10,9%)*Onueiai80274I?ei?oee: * — p<0,01. ** - p<0,001.A?aei?ii?noue iieaciee?a /anoioe ??AE a a?oiao ?eceeo noaoenoe/ii a??ia?aeia (?<0,001), ui na?ae/eoue i?i ei?aeoi?noue iaoaiaoe/ii? iiaeae? oa iaa?oioiaai?noue ?iciiae?eo iaoe??io?a ia a?oie ?eceeo. Ia ae?oaiio aoai? aeine?aeaeaiiy aoei i?iaaaeaii aenia?oio ioe?ieo ?ic?iaeaii? i?iaiinoe/ii? nenoaie (“aecaiai”). A “aecaiaiaoe?eio” aea??eo aoei aeeth/aii 69 iaoe??io?a c AEIAeA. *anoioa ??AE i?ae /an i?iaaaeaiiy “aecaiaio” aeey a?oi iaeiai, na?aaeiueiai oa aenieiai ?eceeo neeaea a?aeiia?aeii 3,9, 33,3 ? 91,7% ? a??ia?aeii ia a?ae??ciyeany (?>0,05) a?ae oaei? o a?oi? “iaa/aeueii?” aea??ee. Oea iiaeoaa?aeaeo?
aaeaeaaoi?noue canoiniaaii? iaoaiaoe/ii? iiaeae? oa i?aeoe/io oeiiiinoue
?ic?iaeaiiai iaoiaeo i?iaiicoaaiiy, a oaeiae ?ic?aooieiao /ooeea?noue oa
niaoeeo?/i?noue iiaeae?. Iaaaaeaia nenoaia i?iaiicoaaiiy iiaea
aeei?enoiaoaaoeny ye eiii’thoa?ia i?ia?aia ia aac? i?ia?aiiiai i?iaeoeoo
“Excel 7.0” iaeaoo “Office”. Cao?aoiee /an iaeiiai ia/eneaiiy ia
ia?aaeuo? 30 n.

I?ney i?iaaaeaiiy iaoaiaoe/ieo ia?aoai?aiue ie io?eiaee ni?iuaiee
aa??aio ia/eneaiiy F, yeee iiaeooue canoiniaoaaoe i?aeoe/i? e?ea??:

?ecee ??AE (a aaeao) = 3O1 + 2O2 + O3 + O4
(6)

O ?ac? ia/eneaiiy e?eueeino? aae?a ca ??aiyiiyi (6) aeey oai?eo c iaeei
?eceeii aeieeiaiiy ??AE aiia neeaaeaea <10, ?c na?aaei?i - a?ae 10 aei 16, c aenieei - a?eueoa 16. I?e ni?anoaaeaii? oa?i?i?a aeieeiaiiy ??AE aeyaeaii, ui a a?oi? aenieiai ?eceeo ??AE o 85% iaoe??io?a aeieeaa a ia?o? 24 aiae (o oiio /ene? o 41,7% - aei 12 aiae), oiae? ye o a?oi? na?aaeiueiai ?eceeo o 63,2% oai?eo ??AE aeieeaa i?ioyaii 24-48 aiae c iiiaioo aini?oae?caoe??. A a?oi? iaeiai ?eceeo nooo?ai? ??cieoe? o oa?i?iao ?icaeoeo ??AE ia aeyaeaii (?en.2). Canoinoaaiiy iaoiae?a aiaeineii?/iiai cae??ieaiiy aaiinoaco o ae?acoe? ie?aeiooai?thaaeueieie iie?ia?aie ia ni?eyei cieaeaiith /anoioe ??AE. Oae, ??AE i?e canoinoaaii? oa aac canoinoaaiiy aiaeineii?/ieo iaoiae?a aaiinoaco niinoa??aaeeny a a?oi? aenieiai ?eceeo o 93,3 ? 95,2%, na?aaeiueiai - o 43,1 ? 54,5%, iaeiai - o 4,2 ? 7,9% iaoe??io?a a?aeiia?aeii (?>0,05).

Ia iniia? aeaieo a?aeiinii /anoioe oa aeeiai?ee ?icaeoeo ??AE, a oaeiae
cai?iiiiiaaii? nenoaie i?iaiicoaaiiy ?o aeieeiaiiy aoa ?ic?iaeaiee
aeai?eoi o??o?a?/ii? oaeoeee, iaa?oioiaai? e?eoa??? aeno?aiino?
aeeiiaiiy iia?aoeaieo ao?o/aiue c o?aooaaiiyi a?oie ?eceeo ??AE. On?
iia?aoeai? ao?o/aiiy iiae?eai? ia o?e aeaee:

aeno?ai?, ye? aeeiiothoue a ia?o? 1-2 aiae o iaoe??io?a c iciaeaie
e?iaioa/?, ui i?iaeiaaeo?oueny, oa iaaoaeoeaiino? iaoiae?a
aiaeineii?/iiai aaiinoaco;

iaa?aeeeaaei?, ui aeeiiothoueny o oai?eo a?oie aenieiai ?eceeo ??AE o
ia?o? 6-12 aiae, a na?aaeiueiai ?eceeo — i?ioyaii 12-24 aiae c iiiaioo
aini?oae?caoe??;

?aii? a?aeno?i/ai?, ui aeeiiothoue /a?ac 2-4 aeiae o oai?eo c iaeei
?eceeii ??AE.

Oaeee i?aeo?ae aei o??o?a?/ii? oaeoeee caaacia/o? ciaioaiiy /enea
iia?iaaieo ia aenio? ?aoeeaeeaii?, ye i?aaeei, cia/ii aaae/i? e?iaioa/?.

Cai?iiiiiaaiee aeai?eoi aeei?enoaii o 130 oai?eo c AEIAeA oa i?iaaaeaii
aiae?c oaeoi??a ?eceeo aeieeiaiiy i?neyiia?aoe?eieo oneeaaeiaiue (oaae.
5).

Oaaeeoey 5. Oaeoi?e ?eceeo i?e cai?iiiiiaaiiio aeai?eoi? o??o?a?/iiai
e?eoaaiiy

Oaeoi?eA?oia oai?eo aac oneeaaeiaiue (a?oia A)A?oia oai?eo c
oneeaaeiaiiyie (a?oia A)AA1+A2A2

1.AENO?AI?NOUe IIA?AOe?? Aeno?aia (n=23)19 (82,6%)

4 (17,4%)2 (8,7%) Iaa?aeeeaaeia (n=41)37 (90,2%)4 (9,8%)-
?aiiy a?aeno?i/aia (n=66) 63 (95,5%)

3 (4,5%)-

2.AEAeE IIA?AOe?E 1 ?acaeoe?y oeoiea (n=14)12 (85,7%)2 (14,3%)-

I?aaiicaa??aath/? (n=114)107 (93,9%)7(6,1%)*-3.NOOI?IUe E?IAIOA*?:
Iii??iee (n=52)50 (96,2%)2 (3,8%)-

Na?aaei?e (n=43)39 (90,7%)4 (9,3%)-

Aaaeeee (n=35)30 (85,7%)5 (14,3%)2 (5,7%)

4. A?E OAI?EO aei 40 ?ie?a (n=49)48 (98.0%)1 (2,0%)-

a?ae 40 aei 60 ?ie?a (n=50)46 (92,0%)4 (8,0%)- noa?o? ca 60
?ie?a(n=31)25 (80,6%)6 (19,4%)*2 (6,4%)I?ei?oee: 1- aac o?aooaaiiy
ia?aaeeeaeueieo ao?o/aiue, * — p<0,05. I?e ni?anoaaeaii? oaeoi??a ?eceeo iia?aoeaiiai e?eoaaiiy oai?eo iniiaii? a?oie aei ai?iaaaeaeaiiy aeai?eoio (n=234, oaae. 1) oa eiio?ieueii? a?oie i?ney ai?iaaaeaeaiiy aeai?eoio (n=130, oaae. 5) aeyaeaii, ui ai?iaaaeaeaiiy eaoaai??? iaa?aeeeaaeieo iia?aoe?e a 2,6 ?aco ciaioeei /anoeo aeno?aieo iia?aoe?e (c 44 aei 17%, p<0,001), o oiio /ene? a 2,7 ?aco - ia aenio? ??AE (a?aeiia?aeii c 35,5 aei 13,1%, p<0,001). I?iaaaeaiiy iaa?aeeeaaeieo iia?aoe?e o ?ac? caa?ice ??AE aeicaieeei ciaioeoe e?euee?noue oai?eo, iia?iaaieo a oiiaao aaaeeiai nooiaiy e?iaioa/? ca ?aooiie cieaeaiiy /anoee ao?o/aiue, ui aeeiioaaeenue ia aenio? ?aoeeaeeao e?iaioa/?, c 70,8% a iniiai?e a?oi? aei 26,9% - a eiio?ieuei?e, oiaoi a 2,6 ?aco. ?ic?iaea iiaeo aeae?a iia?aoeaieo ao?o/aiue aeicaieeea iaeaea a 2 ?ace ciaioeoe - c 20,1% a iniiai?e aei 10,8% a eiio?ieuei?e a?oi? e?euee?noue ?acaeoe?e oeoiea. Iaie ?ic?iaeaii iiaee "Niin?a o??o?a?/iiai e?eoaaiiy e?iaioi/eaeo iaaeieinini/eiaeo ae?acie aeaaiaaeoeyoeiaei? eeoee" (iaoaio Oe?a?ie ?22940A), nooue yeiai iieyaa? o oiio, ui i?e ?aaeeeaeueiiio ao?o/aii? ia ae?acoe? aeeiio?oueny o?ainaeoiaeaiaeueia oa o?ainiai?ey?ia ciai?oi? ae?aioaaiiy oieaaeioo, ui cieaeo? ?ecee aeieeiaiiy i?neyiia?aoe?eieo oneeaaeiaiue (?en.3). O oe?eiio cai?iaaaeaeaiiy cai?iiiiiaaiiai aeai?eoio aeicaieeei cieceoe /anoioo oneeaaeiaiiai ia?aa?ao i?neyiia?aoe?eiiai ia??iaeo o oai?eo eiio?ieueii? a?oie aei 7% (iniiaii? -15,8%, ?<0,05), o oiio /ene? c eaoaeueiei iane?aeeii - aei 1,5% (a iniiai?e a?oi? - 4,7%). Oaeei /eiii, ?ic?iaeaia nenoaia i?iaiicoaaiiy ??AE oa iaaaaeaiee aeai?eoi aeai?o o??o?a?/ii? oaeoeee ? aaaeeeaei ?aca?aii iie?auaiiy ?acoeueoao?a e?eoaaiiy oai?eo c AEIAeA. AENIIAEE Oaeoi?aie ?eceeo, ui aieeaathoue ia ?acoeueoao iia?aoeaiiai e?eoaaiiy oai?eo c AEIAeA, ? aeno?ai?noue oa iaoiae iia?aoe??, nooi?iue aaaeeino? e?iaioa/?, a oaeiae a?e oai?iai. Oneeaaeiaiiy oa ??aaiue eaoaeueiino? i?e aeno?aieo iia?aoe?yo ia aenio? e?iaioa/? o 2,7 oa 5,9 ?aco aeu?, i?ae i?e ?aii?o a?aeno?i/aieo; i?ney ?O - a?aeiia?aeii a 5,8 oa 6,5 ?aco, i?ae i?e i?aaiicaa??aath/eo iia?aoe?yo. O ?ac? cia/ii? e?iaioa/? aaaeeiai nooiaiy oneeaaeiaiee ia?aa?a i?neyiia?aoe?eiiai ia??iaeo niinoa??aa?oueny a 2 oa 4,6 ?aco /ano?oa, i?ae o ?ac? na?aaeiueiai oa iii??iiai, a eaoaeuei?noue c?inoa? c 0% i?e iii??iiio nooiai? aei 10,9% i?e aaaeeiio; o iaoe??io?a o a?oe? noa?oa ca 60 ?ie?a - o 5,4 oa 4,9 ?aco ii??aiyii c oai?eie o a?oe? aei 60 ?ie?a. Na?aae aeno?aieo iia?aoe?e ia aenio? e?iaioa/? i?e iaaoaeoeaiino? aiaeineii?/ieo cania?a aaiinoaco aeioe?eueii aeae?eyoe AI ia aenio? e?iaioa/?, ui i?iaeiaaeo?oueny, oa AI ia aenio? ??AE. *anoioa AI ia aenio? ??AE nyaa? 80%, a?i iiaeeaeth? ii?ooaiiy aiiainoaco oa coiiaeth? iaaea?aei? oiiae aeey aoaeue-yeiai aeaeo AI. ?ic?iaeaiee iaoiae aeicaiey? c a??ia?aei?noth 85% i?iaiicoaaoe ia o?eueee a??ia?aei?noue aeieeiaiiy ??AE, a e aeae?eeoe a?oie oai?eo c aenieei ?eceeii (eiia??i?noue aeieeiaiiy ??AE-89,1% a ia?o? 24 aiae), na?aaei?i (eiia??i?noue ?icaeoeo ??AE - 63,2% i?ioyaii 24-48 aiae) oa iaeei (eiia??i?noue aeieeiaiiy ??AE -5,6% aac nooo?ai? ??cieoe? a oa?i?i? ?icaeoeo ?aoeeaeeao). A?aeianaiiy oai?eo c AEIAeA aei iaaii? a?oie ?eceeo ??AE ? iaeiei c aieiaieo e?eoa???a aeai?o o??o?a?/ii? oaeoeee, iaoiaeo iia?aoe?? oa oa?i?io ?? aeeiiaiiy. O oai?eo a?oie aenieiai ?eceeo iieacai? iaa?aeeeaaei? iia?aoeai? ao?o/aiiy a ia?o? 6-12 aiae, na?aaeiueiai - i?ioyaii 12-24 aiae, iaeiai - a ?aii?e a?aeno?i/aiee ia??iae i?e ?iaeea?aeoaeueiiio aecia/aii? iieacaiue aei o??o?a?/iiai e?eoaaiiy. Cai?iiiiiaaiee aeai?eoi iioei?caoe?? o??o?a?/iiai e?eoaaiiy AEIAeA c o?aooaaiiyi a?oie ?eceeo aeicaiey? ciaioeoe /enei AI ia aenio? ??AE c 35,5 aei 13,1%, i?e aaaeeiio nooiai? e?iaioa/? - c 70,8 aei 26,9%, e?euee?noue ?acaeoe?e oeoiea a 2 ?ace, cieceoe /anoioo i?neyiia?aoe?eieo oneeaaeiaiue c 15,8 aei 7%, a eaoaeuei?noue - c 4,7 aei 1,5%. I?AEOE*I? ?AEIIAIAeAOe?? Aea?? o??o?a?/ii? oaeoeee i?e AEIAeA ia? aacoaaoeny ia ioe?ioe? oaeoi??a ?eceeo aeno?aiino? aeeiiaiiy oa iaoiaeo iia?aoe??, nooiaiy e?iaioa/?, a?eo iaoe??ioa. Na?aae aeno?aieo iia?aoe?e ia aenio? e?iaioa/? aeioe?eueii aeae?eyoe aeno?ai? iia?aoe?? ia aenio? e?iaioa/?, ui i?iaeiaaeo?oueny, oa aeno?ai? iia?aoe?? ia aenio? ?? ?aiiueiai ?aoeeaeeao ca a?aenooiino? aoaeoo a?ae aiaeineii?/ieo cania?a aaiinoaco. ?ic?iaeaiee iaoiae i?iaiicoaaiiy a??ia?aeiino? ??AE aeicaiey? aeae?eyoe oai?eo c aenieei (85-95%) ?eceeii ?aoeeaeeao e?iaioa/? a ia?o? 24 aiae, na?aaei?i (50-60%) i?ioyaii ia?oeo 48 aiae oa iaeei ?eceeii (iaioa 5%). O ca`ceo c oeei o oai?eo ca oiiae aenieiai ?eceeo ??AE aeioe?eueii i?iaiaeeoe o??o?a?/ia ao?o/aiiy a ia?o? 6-12 aiae, na?aaeiueiai ?eceeo - i?ioyaii 12-24 aiae, iaeiai ?eceeo - a ?aii?e a?aeno?i/aiee ia??iae. Aeaiee aeai?eoi aeicaiey? ciaioeoe e?euee?noue iia?aoe?e ia aenio? e?iaioa/?, aaea?/? ciaioeoe ieoiio aaao ?acaeoe?eieo iaoiae?a, cieceoe /anoioo i?neyiia?aoe?eieo oneeaaeiaiue oa iieacieee eaoaeueiino?. IA?AE?E ?IA?O, AEAeAIEO CA OAIITH AeENA?OAOe?? 1. O??o?a?/ia oaeoeea i?e ae?aceia?e oai?ia?, oneeaaeiai?e ii?aeiaiiyi ia?oi?aoe?? oa e?iaioa/? // Ee?i. o??o?a?y.- 1997.- ?9-10.- N.11-12 (o ni?aaao. c I.Ae.Oii?iei, I.A.Iia/). 2. Iaoaio 22940A Oe?a?ie, “UA” IIE A 61 A 17/00 Niin?a o??o?a?/iiai e?eoaaiiy e?iaioi/eaeo iaaeieinini/eiaeo ae?acie aeaaiaaeoeyoeiaei? eeoee / ni?aaao. Oaiaoueei ?.I (Oe?a?ia). Iiaeaii 03.01.97; Aeaeaii 05.05.98.-Athe. “I?iieneiaa aeani?noue” ?3.- N.51. 3. Ioeaiea i?iaiinoe/aneeo e?eoa?eaa ?aiieo ?aoeeaeeaia ycaaiiiai e?iaioa/aiey // E?ea?nueea ni?aaa.-1998.-?1.-N.137-139. 4. I?neyiia?aoe?ei? iiaaiii?? o oai?eo c aano?iaeoiaeaiaeueieie ae?aceaie // Oe?. iaae. /aniien.- 1998.- ?4.- N.134-136. (o ni?aaao. c I.Ae.Oii?iei, I.?.E?nniaei). 5. Iaa?aeeeaaeia ?iooc?eia oa?ai?y o oai?eo c ae?aceiaeie oeoieiai-eeoeiaeie e?iaioa/aie a noai? aaii?aa?/iiai oieo // No/ani? i?iaeaie aaiaoieia?? oa o?ainooc?ieia??: oace aeiiia?aeae iaoeiai-i?aeoe/ii? eiioa?aioe?? iieiaeeo a/aieo oa oao?aoe?a.- Ee?a, 1998.- N.52. (o ni?aaao. c N.A.Oaaei??a) 6. Eeeie/aneay yooaeoeaiinoue noeeaieia i?e ycaaiiuo e?iaioa/aieyo o eeoe iiaeeeiai e noa?/aneiai aic?anoa // Iaaeeoeeineea aanoe. - 1997.- ?3. - N.48.(o ni?aaao.c I.Ae.Oii?iei, A.A.Ia?ao, A.A.Aiaiei,) 7. Yiaeineiie/aneay aeaia?aaoeey aeaeoaeea a ea/aiee aeoiaeaiaeueiuo yca // Iiaia a aeeaaiinoeea e ea/aiee caaieaaaiee i?aaiia ieuaaa?aiey: iao/.-i?aeo. eiioa?aioeey. - Oa?ueeia, 1994. - N.204-205. (o ni?aaao. c I.Ae.Oii?iei,?.I.Oaiaoueei,A.E.I?e?oa?aei) 8. Ioeaiea oaeoi?ia ?enea i?e auai?a oe?o?ae/aneie oaeoeee o aieueiuo n e?iaioi/aueie ieei?iaeoiaeaiaeueiuie ycaaie //Aeooaeuei? i?iaeaie iaaeaiiy aeno?aii? iaaee/ii? aeiiiiiae i?e iaa?aeeeaaeieo noaiao: iaoa??aee iaoe.-i?aeo. eiioa?aioe??. - Ee?a, 1995. - N.69-70. (o ni?aaao. c I.Ae.Oii?iei) 9. Aeeaaiinoeea e ea/aiea ino?uo aeaeoaei/ii-eeoa/iuo e?iaioa/aiee // Aeooaeuei? i?iaeaie iaaeaiiy aeno?aii? iaaee/ii? aeiiiiiae i?e iaa?aeeeaaeieo noaiao: iaoa?. iaoe.-i?aeo. eiioa?aioe??. - Ee?a, 1995. - N.34-35. (o ni?aaao. c A.Ae.A?aoonai, I.Ae.Oii?iei, ?.A.Oaaei??a, ?.I.Oaiaoueei, ?.E.E?nniaei, A.?.I?e?oa?aei). 10. I?iaiinoe/aneea oaeoi?u ?enea iia?aoeaiiai ea/aiey aieueiuo n ino?ie?iaioi/aueie ieei?iaeoiaeaiaeueiuie ycaaie // Oe?o?ae/aneia ea/aiea ?aoeeaeeae?othueo aano?iaeoiaeaiaeueiuo yca e eo ineiaeiaiee: iaoa?. ?anioaeeeaineie iao/.-i?aeo. eiioa?aioeee. - Eeaa, 1995. - N.57-58. (o ni?aaao. c A.Ae.A?aoonai, ?.A.Oaaei??a, I.A.Caieaanueeei, ?.A.Iaeueieeii). 11. ?aiiea iineaiia?aoeeiiiua ineiaeiaiey e?iaioi/aueo aeoiaeaiaeueiuo yca n aeeeoaeueiui ycaaiiui aiaiiacii // Oe?o?ae/aneia ea/aiea ?aoeeaeeae?othueo aano?iaeoiaeaiaeueiuo yca e eo ineiaeiaiee: iaoa?. ?anioaeeeaineie iao/.-i?aeo. eiioa?aioeee. - Eeaa, 1995. - N.111-112. (o ni?aaao.c A.Ae.A?aoonai, I.A.A?eyeia-A?euenueeei, I.?.E?nniaei). 12. Eeeieei-yiaeineiie/aneea ?acoeueoaou iia?aoeaiiai ea/aiey e?iaioi/aueo ieei?iaeoiaeaiaeueiuo yca // Oe?o?ae/aneia ea/aiea ?aoeeaeeae?othueo aano?iaeoiaeaiaeueiuo yca e eo ineiaeiaiee: iaoa?. ?anioaeeeaineie iao/.-i?aeo. eiioa?aioeee. - Eeaa, 1995. - N.48-49. (o ni?aaao. c A.?.I?e?oa?aei,N.A.Aieia?iei, I.I.Noaoeue). 13. I?e/eiu eaoaeueiinoe i?e eiina?aaoeaiii ea/aiee ino?ie?iaioi/aueo ieei?iaeoiaeaiaeueiuo yca // Oe?o?ae/aneia ea/aiea ?aoeeaeeae?othueo aano?iaeoiaeaiaeueiuo yca e eo ineiaeiaiee: iaoa?. ?anioaeeeaineie iao/.-i?aeo. eiioa?aioeee. - Eeaa, 1995. - N.60-61. 14. Ae?aaiinoe/i? e?eoa??? ia?oi?aoe?? e?iaioi/eaeo aano?iaeoiaeaiaeueieo ae?acie // ?ioi?iaoe?eiee eeno ?88, 95, Aeione 6. (o ni?aaao. c I.Ae.Oii?iei, I.A.Iia/, ?.I.Oaiaoueei, A.I.Iaoeeaiue). 15. Influence of suture materials on the healing internal suture-line after gastric surgery // International wound organisation: the 4th International Congress. - Tel-Aviv, Israel, 1996. - ?.24. ( o ni?aaao.c I.Ae.Oii?iei, A.?.I?e?oa?aei) 16. Iiaeeeaino? oa ia?niaeoeae e?eoaaiiy aino?eo ae?aceiaeo e?iaioa/ // No/ani? aniaeoe iaa?aeeeaaeii? iaaee/ii? aeiiiiiae: iaoa?. tha?eaeii? iaoe.-i?aeo. eiioa?aioe??, i?enay/aii? 25-??//th noai?aiiy Euea?anueei? i?nueei? ee?i?/ii? e?ea?i? oaeaeei? iaaee/ii? aeiiiiiae. - Euea?a, 1997.- N.182-183. (o ni?aaao. c I.Ae.Oii?iei, A.Ae.A?aoonai, I.?.E?nniaei, ?.?.Ia?ao, I.A.?aai/ia). 17. Iainiiaaiea oe?o?ae/aneie oaeoeee i?e ea/aiee ino?ie?iaioi/aueo aano?iaeoiaeaiaeueiuo yca // Actualitati in chirurgia toracoabdominala.Rezumatele lucrarilor congresuli al VIII-LEA de chirurgie. - Chisinau, 1997. - P.121-122 (o ni?aaao.c I.Ae.Oii?iei, ?.A.Oaaei??a, I.A.Aaeyeia-Aaeuenueeei, I.?.E?nniaei, I.A.Aoee/, I.A.Aiaeey, O.A. Iie?uoe, N.A.Oaaei??a). 18. I?iaeaia aeeaaiinoeee e oe?o?ae/aneie oaeoeee i?e ino?uo aeaeoaei/ii-eeoa/iuo e?iaioa/aieyo // Actualitati in chirurgia toracoabdominala.Rezumatele lucrarilor congresuli al VIII-LEA de chirurgie. - Chisinau, 1997. - ?.88-89(o ni?aaao. c A.Ae.A?aoonai, I.Ae.Oii?iei, ?.I.Oaiaoueei, I.A.Caieaanueeei, A.I.Neaei?aiei). 19. I?e/eiu ?aiieo iineaiia?aoeeiiiuo ineiaeiaiee a oe?o?aee e?iaioi/aueo aano?iaeoiaeaiaeueiuo yca // Actualitati in chirurgia toracoabdominala.Rezumatele lucrarilor congresuli al VIII-LEA de chirurgie. - Chisinau, 1997. - ?.153-155( o ni?aaaoi?noa? c I.?.E?nniaei, I.A.Iia/). 20. I?iaiice?iaaiea ?enea ?aoeeaeeaiiai e?iaioa/aiey o aieueiuo n ino?ie?iaioi/aueie ieei?iaeoiaeaiaeueiuie ycaaie // Aeeaaiinoeea e oe?o?ae/aneia ea/aiea caaieaaaiee e iia?aaeaeaiee aiaia/aii/iuo aeae/iuo i?ioieia: iaoa?. ?anioaeeeaineie iao/.-i?aeo. eiioa?aioeee. - Eeaa, 1996. - N.124-125 . 21. Ee?i?ei-aiaeineii?/i? e?eoa??? iaa?oiooaaiiy o??o?a?/ii? oaeoeee i?e e?iaioi/eaeo i?ei?iaeoiaeaiaeueieo ae?aceao // Aeooaeuei? i?iaeaie iaa?aeeeaaeii? o??o?a?? i?aai?a /a?aaii? ii?iaeieie oa o?iaai?oaeueiiai o?aeoo: iaoa?. ?anioae?eainueei? iaoe.-i?aeo. eiioa?aioe??. - Ee?a, 1996. - N.35-36 (o ni?aaao. c I.Ae.Oii?iei, ?.I.Oaiaoueei, ?.A.Oaaei??a, I.A.?aiaoiaei, A.A.Oanaiei, I.I.Oa?eoeiei, ?.?.Ia?ao). 22. Nii?iua aii?inu oe?o?ae/aneie oaeoeee i?e ino?ie?iaioi/aueo aano?iaeoiaeaiaeueiuo iaioe/aneeo ycaao // Iiaua oaoiieiaee a oe?o?aee: nai?iee iao/iuo ?aaio. - Eeaa: “A?o A?aoee”, 1997. - N.17 (o ni?aaao. c A.Ae.A?aoonai, I.Ae.Oii?iei, ?.I.Oaiaoueei, I.A.Iia/, N.A.Oaaei??a, I.A.Caieaanueeei). 23. Oaeoi?u ?enea ?aiiaai ?aoeeaeeaa e?iaioa/aiey i?e ino?ie?iaioi/aueo ieei?iaeoiaeaiaeueiuo ycaao // Iiaua oaoiieiaee a oe?o?aee: nai?iee iao/iuo ?aaio. - Eeaa: “A?o A?aoee”, 1997. - N.36-37 (o ni?aaao. c I.Ae.Oii?iei, ?.I.Oaiaoueei, I.?.E?nniaei, I.A.Iia/). 24. Peptic ulcer as wound of stomach and duodenum // International wound organisation: the 5th International Congress.- Tel-Aviv, Israel, 1998. - ?.29.( o ni?aaao.c I.Ae.Oii?iei, C.A.Oaaei??a, A.A.Caieaanueeei, ?.?.Ia?ao). 25. Iioei?caoe?y iaoiae?a o??o?a?/iiai e?eoaaiiy oai?eo c aino?ie?iaioi/eaeie i?ei?iaeoiaeaiaeueieie ae?aceaie // Aeooaeueiua aii?inu iaioeiaeiie oe?o?aee i?aaiia a?thoiie iieinoe: na. iao/. o?. - Oa?ueeia, 1998.- N.145-147. (o ni?aaao. c I.Ae.Oii?iei, ?.I.Oaiaoueei). 26. Iieacaiiy oa iniaeeaino? aeeiiaiiy ?aeaia?aoii?? i?e ai?eii-naioe/ieo oneeaaeiaiiyo a o??o?a?? aano?iaeoiaeaiaeueii? ae?acee // Ca??iee iaoeiaeo i?aoeue ?? eiia?ano o??o?a?a Oe?a?ie.- Ee?a-Aeiiaoeuee,1998.-N.564-565. (o ni?aaao. c I.Ae.Oii?iei, I.?. E?nniaei). AIIOAOe?ss N.I. Eiceia. Ioe?iea oaeoi??a ?eceeo i?e aeai?? o??o?a?/ii? oaeoeee o oai?eo c aino?ie?iaioi/eaeie i?ei?iaeoiaeaiaeueieie ae?aceaie. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.03. - “O??o?a?y”. Iaoe?iiaeueiue iaaee/iee oi?aa?neoao ?i. I.I. Aiaiiieueoey. Ee?a,1999. ?iaioa i?enay/aia ieoaiiyi iioei?caoe?? o??o?a?/ii? oaeoeee, oa?i?io oa iaoiae?a o??o?a?/iiai e?eoaaiiy oai?eo c aino?ie?iaioi/eaeie i?ei?iaeoiaeaiaeueieie ae?aceaie. I?e iiiioaeoi?iiio aiae?c? aeyaeaia /anoioa ?aii?o i?neyiia?aoe?eieo oneeaaeiaiue i?e ??cieo niiniaao o??o?a?/iiai e?eoaaiiy caeaaeii a?ae aeno?aiino? ao?o/aiiy, nooiaiy e?iaioa/?, a?eo iaoe??ioa. I?neyiia?aoe?ei? oneeaaeiaiiy oa eaoaeuei?noue i?ney ?acaeoe?eieo iaoiae?a aoee o 5,8 oa 6,5 ?aco aeueie, i?ae i?ney i?aaiicaa??aath/eo ao?o/aiue, o iaoe??io?a o a?oe? noa?oeo ca 60 ?ie?a - a?aeiia?aeii o 5,4 oa 4,9 ?aco aeueie, i?ae a a?oi? iaoe??io?a o a?oe? aei 60 ?ie?a. Ine?eueee 80% aeno?aieo iia?aoe?e ?iaeee ia aenio? ?aiiueiai ?aoeeaeeao ae?aceiai? e?iaioa/? (??AE), c aeei?enoaiiyi iaoiaeeee iie?ieiaiai aeene?ei?iaioiiai aiae?co aoee aea/ai? oaeoi?e, ui aecia/athoue eiai ?icaeoie. ?ic?iaeaia nenoaia i?iaiicoaaiiy ??AE, aeae?eai? a?oie ?eceeo oa iaa?oioiaaii aeeiiaiiy iaa?aeeeaaeieo ao?o/aiue aeey eiai iiia?aaeaeaiiy. Cai?iiiiiaaiee aeai?eoi aeai?o o??o?a?/ii? oaeoeee aeeth/a? aeeiiaiiy iaa?aeeeaaeieo ao?o/aiue o iaoe??io?a c aenieei ?eceeii ??AE, iaiaaeaiiy aeei?enoaiiy ?acaeoe?eieo iaoiae?a o?eueee aeiaaeeaie aeaeiiiainiaaiiai noaiico, aeeiiaiiy i?aaiicaa??aath/iai ao?o/aiiy i?e iaaeieinini/eiaiio ?icoaooaaii? ae?acee. Eeth/ia? neiaa: ae?aceiaa oai?iaa aeaaiaaeoeyoeiaei? eeoee, oneeaaeiaia e?iaioa/ath; ?aii?e ?aoeeaeea ae?aceiai? e?iaioa/?; oaeoi?e ?eceeo; aeai?eoi aeai?o o??o?a?/ii? oaeoeee; i?aaiicaa??aath/? iia?aoeai? ao?o/aiiy. AIIIOAOeEss N.I. Eiceia. Ioeaiea oaeoi?ia ?enea i?e auai?a oe?o?ae/aneie oaeoeee o aieueiuo n ino?ie?iaioi/aueie ieei?iaeoiaeaiaeueiuie ycaaie. - ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.03. - “Oe?o?aey”. Iaoeeiiaeueiue iaaeeoeeineee oieaa?neoao ei. A.A. Aiaiiieueoea. Eeaa,1999. ?aaioa iinayuaia aii?inai iioeiecaoeee oe?o?ae/aneie oaeoeee, i?aaeaea anaai n?ieia e iaoiaeia oe?o?ae/aneiai ea/aiey o aieueiuo n ino?ie?iaioi/aueie ieei?iaeoiaeaiaeueiuie ycaaie (IEIAess). A oiaea enneaaeiaaiey i?iaaaeaiu aiaeec e ioeaiea oaeoi?ia ?enea ?acee/iuo aeaeia yeno?aiiuo e ?aiieo ion?i/aiiuo iia?aoeee, aiaeec oaeoi?ia ?enea e ?ac?aaioea nenoaiu i?iaiice?iaaiey ?aiiaai ?aoeeaeeaa ycaaiiiai e?iaioa/aiey (??ssE), ?ac?aaioea e aiaae?aiea aeai?eoia iioeiece?iaaiiie oe?o?ae/aneie oaeoeee i?e IEIAess. A ea/anoaa ia?aiao?ia n?aaieoaeueiiai aiaeeca iaiin?aaenoaaiiuo ?acoeueoaoia e auyaeaiey oaeoi?ia ?enea i?e auiieiaiee yeno?aiiuo e ?aiieo ion?i/aiiuo aiaoaoaeuenoa eniieueciaaeenue: a) iaineiaeiaiiia oa/aiea iineaiia?aoeeiiiiai ia?eiaea; a) ineiaeiaiiia oa/aiea iineaiia?aoeeiiiiai ia?eiaea e iineaiia?aoeeiiiay eaoaeueiinoue. A ?acoeueoaoa i?iaaaeaiiiai aiaeeca auyaeaiu neaaeouea iniiaiua oaeoi?u ?enea: yeno?aiiinoue auiieiaiey aiaoaoaeuenoaa, auiieiaiea ?acaeoeee aeaeoaeea, oyaeaeay noaiaiue e?iaioa/aiey ia?aae iia?aoeaiui aiaoaoaeuenoaii, aic?ano iaoeeaioa noa?oa 60 eao. Iineieueeo aei 80% yeno?aiiuo iia?aoeee auiieiyeenue ia aunioa ?aiiaai ?aoeeaeeaa e?iaioa/aiey, auee eco/aiu oneiaey e oaeoi?u, ii?aaeaeythuea aai ?acaeoea. “Iao/athuoth” auai?eo ninoaaeee aeaiiua 354 iaoeeaioia (80 - n ??ssE, 274 - aac ??ssE). Eniieuecoy iaoiaeeeo iioaaiaiai aeene?eieiaioiiai aiaeeca, au/eneaiu eiyooeoeeaiou cia/eiinoe e ii?aaeaeai aeae aeene?eieiaioiuo ooieoeee, ninoaaeaoeo iaoaiaoe/aneoth iiaeaeue i?iaiinoe/aneie nenoaiu. A ea/anoaa i?iaiinoe/aneeo oaeoi?ia auaeaeaiu neaaeothuea: ?acia? ycaaiiiai aeaoaeoa, ninoiyiea aaiinoaca a iai, oyaeanoue e?iaioa/aiey, aic?ano aieueiiai. Aaeaeaaoiinoue iaoaiaoe/aneie iiaeaee iiaeoaa?aeaeaia i?e ?ao?iniaeoeaiii e i?iniaeoeaiii enneaaeiaaiee. ?ac?aaioaiiue iaoiae iicaieyao n aeinoiaa?iinoueth 85% i?iaiice?iaaoue ia oieueei aa?iyoiinoue ianooieaiey ??ssE, ii e auaeaeeoue a?oiiu aieueiuo n aunieei ?eneii (aa?iyoiinoue ??ssE-89,1% a ia?aua 24 /), n?aaeiei (aa?iyoiinoue ??ssE 63,2% ia i?ioyaeaiee 24-48 /) e iaeui (aa?iyoiinoue ??ssE - 5,6%) ?eneii ?acaeoey ??ssE. Ioianaiea aieueiuo n IEIAess e oie eee eiie a?oiia ?enea yaeyaony aaaeouei e?eoa?eai auai?a oe?o?ae/aneie oaeoeee, iaoiaea iia?aoeee e n?ieia aa auiieiaiey. Aeey iaoeeaioia a?oiiu aunieiai ?enea n oeaeueth i?aaeioa?auaiey ??ssE n/eoaee oeaeaniia?aciui auiieiaiea iaioeiaeiuo aiaoaoaeuenoa a oa/aiea 6-12 /, n?aaeiaai - 12-24 /. A a?oiia iaeiai ?enea iia?aoeee auiieiyee a ?aiiee ion?i/aiiue ia?eiae. Oeacaiiue iiaeoiae iicaieee nieceoue /enei yeno?aiiuo iia?aoeaiuo aiaoaoaeuenoa n 44 aei 17% (p<0,001), a oii /enea aeieth aiaoaoaeuenoa, auiieiyaiuo a oneiaeyo oyaeaeie noaiaie e?iaioa/aiey n 70,8 aei 26,9% (p<0,01), /oi iicaieeei oiaiueoeoue aeeyiea oaeeo oaeoi?ia ?enea, eae yeno?aiiinoue oe?o?ae/aneiai aiaoaoaeuenoaa e iia?aoeaiia ea/aiea a oneiaeyo oyaeaeie noaiaie e?iaioa/aiey. Aeey i?aeoe/aneiai eniieueciaaiey ?ac?aaioai aaeeueiue aa?eaio i?iaiinoe/aneie nenoaiu. A oiaea enneaaeiaaiey auyaeaia iaaeinoaoi/iay yooaeoeaiinoue yiaeineiie/aneiai cae?aieaiey aaiinoaca a ycaaiiii aeaoaeoa i?e iiiiue ieaieiia?acothueo iieeia?ia oeia “Eeoocieue” - aai i?eiaiaiea ia nieaeaei aeinoiaa?ii /anoioo ?aoeeaeeaa ai anao a?oiiao ?enea. Aiaeec oaeeo oaeoi?ia ?enea, eae "aeae iia?aoeaiiai ea/aiey" e "aic?ano" iieacae, /oi iineaiia?aoeeiiiua ineiaeiaiey e eaoaeueiinoue ioia/aeenue iinea auiieiaiey ?acaeoeee aeaeoaeea (?AE) a 5,8 e 6,5 ?ac /aua, /ai iinea i?aaiinaa?aaaoaeueiuo aeaeia aiaoaoaeuenoaa, a o aieueiuo a aic?anoa noa?oa 60 eao - niioaaonoaaiii a 5,4 e 4,9 /aua, /ai a aic?anoiie a?oiia aei 60 eao. ?ac?aaioaiiue aeai?eoi auai?a iaoiaea oe?o?ae/aneiai aiaoaoaeuenoaa ninoieo a ia?aie/aiee iieacaiee e auiieiaieth ?acaeoeee aeaeoaeea o iaoeeaioia a aic?anoa noa?oa 60 eao, a oaeaea a neo/ayo aeaeiiiaine?iaaiiiai noaiica auoiaea ec aeaeoaeea eee oee?eoey?iiai ?aniieiaeaiey e?iaioi/auae ycau iicaieyao nieceoue aeieth ?AE o iaoeeaioia eiio?ieueiie a?oiiu n 20,1 aei 10,8%. ?ac?aaioai niinia oe?o?ae/aneiai ea/aiey ieieinini/eiauo IEIAess, caueuaiiue iaoaioii Oe?aeiu, ia iniiaa i?aaiinaa?aaaoaeueiuo iaoiaeia aiaoaoaeuenoaa, /oi iicaieeei ioeacaoueny io ?acaeoeeiiiuo iaoiaeia i?e aeaiiie eieaeecaoeee IEIAess. *anoioa iineaiia?aoeeiiiuo ineiaeiaiee i?e ?AE nieceeanue n 46,8 aei 14,3%, a eaoaeueiinoue - n 14,9 aei 0%. I?e i?iaaaeaiee iaioeiaeiuo aiaoaoaeuenoa a 100% neo/aaa auiieiyeenue i?aaiinaa?aaaoaeueiua aiaoaoaeuenoaa. A oeaeii i?eiaiaiea aeai?eoia iioeiecaoeee iicaieeei oiaiueoeoue eiee/anoai yeno?aiiuo iia?aoeee ia aunioa ?aoeeaeeaa e?iaioa/aiey, nieceoue aeieth aiaoaoaeuenoa, auiieiyaiuo a oneiaeyo oyaeaeie noaiaie e?iaioa/aiey, oaaee/eoue eiee/anoai i?aaiinaa?aaaoaeueiuo aiaoaoaeuenoa o iaoeeaioia eiio?ieueiie a?oiiu a 2 ?aca, nieceoue /anoioo iineaiia?aoeeiiiuo ineiaeiaiee n 15,8 aei 7%, a eaoaeueiinoue - n 4,7 aei 1,5%. Eeth/aaua neiaa: ycaaiiay aieaciue aeaaiaaeoeaoeia?noiie eeoee, ineiaeiaiiay e?iaioa/aieai; ?aiiee ?aoeeaeea ycaaiiiai e?iaioa/aiey; oaeoi?u ?enea; aeai?eoi auai?a oe?o?ae/aneie oaeoeee, i?aaiinaa?aaathuea iia?aoeaiua aiaoaoaeuenoaa. SUMMARY KOSLOV S.N. Evaluation of risk factors of the surgical tactic in the patients with bleeding pyloroduodenal ulcers. - Manuscript. Dissertation for obtaining the degree of candidate of Medical Science on a specialty surgery, code 14.01.03. National medical university named after A.A.Bogomolets. Kyiv,1999. Dissertation is devoted to the problem of improving surgical tactic in patients with bleeding peptic duodenal ulcers. The rate and structure of postoperative complications were analyzed with reference to the method and terms of surgical treatment. Monofactor analyses revealed such risk factors of surgery as emergency of operation, resection methods, severe bleeding and age of the patient. Complications and mortality after resection methods were in 5,8 and 6,5 higher than after organ-preserving operations, in patients older 60 years in.5,4 and 4,9 higher than in group under 60. More than 80% of the emergency operations were performed due to haemorrhage recedive after spontaneous or endoscopical hemostasis. Conditions and risk factors of early recidive haemorrhage (ERH) were studied using stepwise discriminant analysis procedure. Obtained model was used for the predicting risk of haemorrhage recurrence. According to the ERH risk all patients were divided into 3 groups: high, medium and low. Terms of surgical treatment depend upon ERH probability. Urgent operations in patients with high or medium risk were proved effective for ERH prophylaxy. Special algorithm for choosing surgical tactic in patients with bleeding duodenal ulcers included: performing organ-preserving operations in all urgent cases, excluding cases of decompensated stenosis, urgent operations for ERH high risk patients, special organ-preserving surgical procedure for the ulcers situated closely to Vateri duct. Key words: bleeding duodenal ulcer; early recidive of ulcer haemorrhage; risk factors; surgical tactic algorithm; organ-preserving operations.

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