OE?A?INUeEEE IAOEIAI-AeINE?AeIEE

?INOEOOO IAAeE*II? ?AAA?E?OAOe?? OA

EO?I?OIEIA?? IIC OE?A?IE

NIEIAeIAA ??EIA AANEE?AIA

OAeE 616.248-053.2-085:628.8

“ E?EOAAEUeIEE I?E?IEE?IAO

NIAOe?AE?CIAAIEO IAEAO A

EIIIEAENI?E OA?AI?? Ae?OAE,

OAI?EO IA A?IIO?AEUeIO ANOIO ”

14.01.33 – eo?i?oieia?y oa o?c?ioa?ai?y

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa
iaaee/ieo iaoe

Iaeana – 1999

Aeena?oaoe?y ? ?oeiien.

?iaioa aeeiiaia a Caii??cueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

i?ioani? ?aaiueei Ieaa A?eai?iae/

Caii??cueeee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e oaeoeueoaonueei? iaae?ao???

(c 1997 ?. i?aoeth? ii eiio?aeoo a E?a??)

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani?

Coaa?aiei ?ai? Eaii?aeiae/,

Oe?a?inueeee IAe? iaaee/ii? ?aaa?e?oaoe?? oa eo?i?oieia??,

caa?aeoaa/ a?aeae?eaiiyi caoai?thaaiue ae?oae oa i?aee?oe?a,

aeieoi? iaaee/ieo iaoe, i?ioani?

Aaa?e ?ai? Eaii?aeiae/,

Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e i?iiaaeaaoeee aeeoy/eo oai?ia

I?ia?aeia onoaiiaa:

Oe?a?inueeee IAe? aeeoy/i? eo?i?oieia?? oa o?c?ioa?ai?? IIC Oe?a?ie,
a?aeae?e iaaee/ii? ?aaa?e?oaoe?? ae?oae, i. ?aiaoi??y

Caoeno a?aeaoaeaoueny “ 19 ” ethoiai 1999 ?ieo i 13 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 41.608.01 Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo iaaee/ii? ?aaa?e?oaoe?? oa eo?i?oieia??
IIC Oe?a?ie.

Aae?ana: 270014, i. Iaeana, Ea?iiioianueeee i?ia. 6.

Aaoi?aoa?ao ?ic?neaiee “ 17 ” n?/iy 1999 ?ieo.

A/aiee nae?aoa? niaoe?ae?ciaaii?

a/aii? ?aaee, eaiaeeaeao iaaee/ieo iaoe,

noa?oee iaoeiaee ni?a?ia?oiee
Aei?o???aa A.I.

 CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE.

Aeooaeuei?noue i?iaeaie. Ca inoaii? ?iee a on?o e?a?iao na?oo
a?aecia/a?oueny c?inoaiiy /enea oai?eo aea?a?/ieie caoai?thaaiiyie (
A.I.Iooeee, 1994, TH.A.Aaeueo?uaa, 1995, I.?.Eaneoey, 1996, I.Wetztman,
1995). Aeniea caoai?thaai?noue aei?ineeo oa ae?oae ia a?iio?aeueio
anoio iia’ycaia oaeiae ? c i?aeaeuaiiyi caa?oaeiaiiy iia?o?yiiai
na?aaeiaeua. Iaeiei ?c oaeoi??a naiiaaiaco anoie iiaea aooe
i?eieiaiiy ae?? ia neeciao iaieiieo a?iio?a i?e/eiiicia/oueo
aea?aai?a oa ?ioeo iiae?acithth/eo ?a/iaei (A.A.*o/ae?i, 1992,
A.I.Wardlaw,1993).

O ca’yceo c oeei no/ani? i?aeia?iaei? eiioeaioe?? oa?ai??
a?iio?aeueii? anoie i?aee?aneththoue iaiao?aei?noue iie?auaiiy
iaaeieeoiueiai na?aaeiaeua (Aaoanaea, 1992).

Niae?ioa?ai?y, yea c oni?oii aeei?enoiao?oueny a e?eoaaii? a?iio?aeueii?
anoie ? i??i?eoaoiei iai?yieii oe?a?inueei? oeiee aea?aieia?a ?
ioeueiiiieia?a, ii?aeio? a nia? aieea iaea?eueo /enoi? a?ae
aea?aai?a ? i?e?ii?aai?ci?a aoiinoa?e oaoo nieueiaeo ae?ia?oie c
iino?eiith oaiia?aoo?ith ? aieia?noth iia?o?y oa i?ioecaiaeueiee
aoaeo ?ii?ciaaiiai aa?icieth iao??th oei?eaeo ( I.Ae.Oi?ioo?i,,1987,
?.N. Eaiei, 1989, TH.I.Neieeiiea, 1989,, E.E. ?o?iiaa, 1993, A. A?eae,
1994, P.Krasko et.al., 1983, I.Mohapl et.al., 1991 ).

Iaeiae, oe?iea canoinoaaiiy niae?ioa?ai?? iaiaaeo?oueny
oa?eoi??aeueieie oa ?ioeie ianoaaeiaie. A iao /an oe?iei
aeei?enoiaothoueny ??ciiiai?oi? i?eeaaee, caeaoi? /anoeiai iiaeaethaaoe
i?e?iee?iao nieueiaeo oaoo ( I.Ae.Oi?ioo?i, 1990, A.I.Neaeaeueieeia c
ni?aaao., 1989, I.I.Ai?aaiei, 1991). Aeey i/euaiiy iia?o?y
i?ei?uaiue a?ae aea?aai?a canoiniaothoue ??ci? iia?o?yiii/eni?
iaeaaeiaiiy ( I.N. Aaneeue?aa c ni?aaao., 1995, I.A. *o/ae?i, 1995,
M.H. Schata, 1993 ).

Aieiaiith oaiaeaioe??th uiaei oaeineiiaeaiiy iaoiae?a aaeioa?ai??
(e?eoaaiiy nooei aa?icieai iao??th oei?eaeo)? iaea?aeaiiy iiaeeeaino?
?aaoethaaoe ia?aiao?e i?e?iee?iaoo oa i?aeo?eioaaoe ?o o?eaaeee /an,
iaaeeaeath/e ?o aei aoiinoa?e o i?e?iaeieo nieueiaeo oaooao.

Iioeiaeueiei ?aaeeiii oa?ai?? ii?aeiaiiy iino?eiiai i/euaiiy iia?o?y
oa o?eaaei? i?aeo?eiee e?eoaaeueiiai ?ii?ciaaiiai aa?icieth iao??th
oei?eaeo c oa?aeoa?enoeeaie, ui iaaeeaeathoueny aei i?e?iee?iaoo
i?ei?uaiue o nieyieo ae?ia?oeao. Aaaeaiei aaoiiiii?noue i?eeaaeo aeey
noai?aiiy i?e?iee?iaoo oa iiaeeea?noue eiai ia?anoaaiiy.

Ca aeiiiiiaith noai?aiiai iiaiai i?eeaaeo, ?ic?iaeaiiai caii??cueeeie
a/aieie oa oaoi?eaie (aaoi?nueea iina?ae/aiiy i?i aeiao?ae N 1748328 SY
an.II-AI (1990) A.A.Eooa?iaa oa iiceoeaiiai ??oaiiy eii?oaoo ii iia?e
iaaee/i?e oaoi?oe? Oe?a?ie (i?ioieie N 4 a?ae 2 eeiiy 1991?.)), ?
iiaeeeaei noai?aiiy e?eoaaeueiiai i?e?iee?iaoo c eiio?ieueiaaieie
ia?aiao?aie aaciina?aaeiuei a iaeaoao a?aeae?eaiue. Oea iiaea a?aee?eoe
iia? ia?niaeoeae a e?eoaaii? a?iio?aeueii? anoie. Aea oa?aiaaoe/i?
iiaeeeaino? aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo a eiiieaeniiio
e?eoaaii? oai?eo ae?oae a oiiaao cae/aeieo iaeao aea?aieia?/iiai
a?aeae?eaiiy ia iao /an aea/ai? iaaeinoaoiuei, ui iio?aao? aecia/aiiy
aoaeoeaiino? ae?? i?e?iee?iaoo, ui noai?th?oueny , c ianooiiith
?ic?iaeith iioeiaeueieo (aoaeoeaieo) ?aaeei?a oa?ai??.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, oaiaie. Ia?aiee iai?yiie
aeine?aeaeaiue o?nii iia’ycaiee c IAe?, ye? cae?enithaaeenue a
Caii??cueeiio iaaee/iiio oi?aa?neoao? ia eaoaae?? oaeoeueoaonueei?
iaae?ao??? ? i?enay/ai? ?ic?iaoe? i?iaeaie ??cieo iaoiae?a e?eoaaiiy
oai?eo ia aoii?/io a?iio?aeueio anoio

( N aea?ae?a?no?aoe?? 0194 U 008431, 0197 U 001354 )

Iaoith  aeine?aeaeaiiy ?ic?iaea cania?a eiiieaenii? a?aeiiaethaaii?
oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c aeei?enoaiiyi
o?eaaeiai ia?aaoaaiiy a iaeaoao c e?eoaaeueiei i?e?iee?iaoii (
ae??aiiaeenia?niee ?ii?ciaaiee nooee aa?icieue iao??th oei?eaeo c
iino?eiith o?eueo?aoe??th iia?o?y).

 Caaaeaiiy aeine?aeaeaiiy

1. Aea/eoe noai a?iio?aeueii? i?io?aeiino?, aeiaiaeo a?i?eoi?a i?eiai?
oaeaeeino? aeaeeoo o oai?eo ia a?iio?aeueio anoio ae?oae a oiiaao
o?eaaeiai aieeao e?eoaaeueiiai i?e?iee?iaoo niaoe?ae?ciaaieo iaeao.

2. Anoaiiaeoe aieea e?eoaaeueiiai i?e?iee?iaoo iaeao ia
a?ia??aaeoeai?noue a?iio?a i?e o?ce/iiio iaaaioaaeaii?, noai
i?e?ia?ioeaiico neeciaeo iaieiiie aa?oi?o aeeoaeueieo oeyo?a.

3. Aea/eoe iieacieee caa?oaeiaiiy iaeao c e?eoaaeueiei
i?e?iee?iaoii aea?aiaaiieie ee?uaie ?iaeo Dermatophagoides.

4. ?ic?iaeoe iioeiaeuei? ?aaeeie aeei?enoaiiy e?eoaaeueiiai
i?e?iee?iaoo i?ei?uaiue a eiiieaeni?e a?aeiiaethaai?e oa?ai??
ae?oae, oai?eo ia a?iio?aeueio anoio, a oiiaao iaeao
aea?aia?aeae?eaiiy oa ioe?ieoe ?o aoaeoeai?noue ia i?aenoaa?
ee?i?/iiai, eaai?aoi?iiai aeine?aeaeaiue oa a?aeaeaeaieo ?acoeueoao?a.

 Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a

Aia?oa aoa ?ic?iaeaiee oa aeei?enoaiee iiaee iaoiae eiiieaenii?
a?aeiiaethaaii? oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c
canoinoaaiiyi iiaeeo?eiaaii? iaeaoe e?ea?i? c o?eniaaieie ia?aiao?aie
e?eoaaeueiiai i?e?iee?iaoo oa /enoioe iia?o?y. Aecia/aii iioeiaeueiee
?aaeei — uiaeaiia 10 aiaeeiia ia?aaoaaiiy o aoiinoa??
ae??aiiaeenia?niiai nooiai ?ii?ciaaiiai aa?icieth iao??th oei?eaeo c
iino?eiith o?eueo?aoe??th iia?o?y i?ioyaii 15 ae?a. Aeiaaaeaii, ui
aeei?enoaiiy oeueiai iaoiaeo o a?aeiiaethaaeuei?e oa?ai?? oai?eo ia
a?iio?aeueio anoio ae?oae, i?aeaeuo? ?? aoaeoeai?noue ca oiia
oaeaeei? ii?iae?caoe?? a?iio?aeueii? i?io?aeiino?, ii?iae?caoe??
i?e?ia?ioeaiico, ui iiaeiaaeo? ?ai?n?th oai?iae. Anoaiiaeaii, ui
e?eoaaeueiee i?e?iee?iao ni?ey? ?icaeoeo oiea?aioiino? aei o?ce/iiai
iaaaioaaeaiiy o oai?eo ia a?iio?aeueio anoio. Aecia/aii oaeo
cieaeaiiy ??aiy caa?oaeiaiiy na?aaeiaeua ee?uaie iiaooiaiai ieeo a
oiiaao e?eoaaeueiiai i?e?iee?iaoo iaeao.

 I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

?ic?iaeaii oa aei?iaoaaii iiaee can?a eiiieaenii? a?aeiiaethaaii?
oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c canoinoaaiiyi
e?eoaaeueiiai i?e?iee?iaoo iaeao. Eiai aeei?enoaiiy ni?ey?
ciaioaiith o?eaaeino? ia??iaeo caaino?aiiy oai?iae, oa?i?io
ia?aaoaaiiy o noaoe?iia??, iiia?aaeaea? ?aaeoe?? a?iioieiino?eeoe?? i?e
o?ce/iiio iaaaioaaeaii? ca ?aooiie ciaioaiiy nooiaith
a?ia??aaeoeaiino? a?iio?a, ni?ey? a?aeiiaeaiith i?e?ia?ioeaiico aa?oi?o
aeeoaeueieo oeyo?a, ?noioii iie?ioo? a?aeaeaeai? ?acoeueoaoe
e?eoaaiiy ( ciaioaiiy e?eueeino? aaaeeeo iaiaae?a yaeooe, ciaioaiiy
iio?aae a e?eao, i?aeaeuaiith o?eaaeino? ?ai?n??). A iaeaoao c
e?eoaaeueiei i?e?iee?iaoii iie?ioo?oueny a?a??i?/iee noai ca oiia
ciaioaiiy caa?oaeiaiiy aea?aaiieie i?iaeoeoaie aeeoo?ae?yeueiino?
ee?u?a iiaooiaiai ieeo. Ia i?aenoaa? aeine?aeaeaiue i?eiai? oaeaeeino?
aeaeeoo (IOA) 383 caei?iaeo ae?oae aeaaaeai? ?aa?an?? ii??aiyiiy
i?i?iaeueieo cia/aiue IOA ( a caeaaeiino? a?ae noao? oa c?inoo ae?oae).

Io?eiai? ?acoeueoaoe aoee aeiaaaeai? oa iaaiai?ai? ia
Caii??cuee?e iaeani?e iaoeiai-i?aeoe/i?e eiioa?aioe?? o?c?ioa?aiaao?a,
aea aoei noaaeaii aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo a oa?ai??
oai?eo ia a?iio?aeueio anoio.

?acoeueoaoe aeine?aeaeaiue oi?iaaaeaeai? a i?aeoeeo ?iaioe iaeaniiai
aea?aieia?/iiai a?aeae?eaiiy oa iie?ee?i?/iiai a?aeae?eaiiy aeeoy/i?
ee?i?/ii? e?ea?i? N 5 i. Caii??aeaey, aea?aioeaio?o i. Caii??aeaey,
iaeanii? e?ea?i? i. Aei?i?iiao?ianueea, niae?inaiaoi??th «Aeiiaan»
i.A?oai?anuee Aeiiaoeueei? iaeano?.

 Iniaenoee aianie caeiaoaa/a.

Aeena?oaioii naiino?eii ianoaaeaii 225 ae?oae, oai?eo ia
a?iio?aeueio anoio, ye? ciaoiaeeeenue a aea?aieia?/iiio a?aeae?eaii?.
?ic?iaeaii iaeiioeiaeuei?oee ?aaeei a?aeiiaethaaii? oa?ai?? a oiiaao
e?eoaaeueiiai i?e?iee?iaoo iaeao ( ae??aiiaeenia?niee nooee
?ii?ciaaiee aa?icieue iao??th oei?eaeo iecueei? eiioeaio?aoe?? oa
iino?eii? o?eueo?aoe?? iia?o?y). Anoaiiaeai? ii?iaeuei? iieacieee
i?eiai? oaeaeeino? aeaeeoo (IOA) o ae?oae, iaoeaioe?a i. Caii??aeaey
(383) oa ??aiyiiy aeey i?ae?aooieo IOA. Anoaiiaeaii oaeo cia/iiai
cieaeaiiy ??aiy caa?oaeiaiiy na?aaeiaeua iaeao c e?eoaaeueiei
i?e?iee?iaoii ee?uaie iiaooiaiai ieeo ( iaoiaeii o?iiaoia?ao?/iiai
aeine?aeaeaiiy e?eueeino? aoai?io). I?iaaaeaia ioe?iea aoaeoeaiino?
e?eoaaeueiiai i?e?iee?iaoo iaeao ca ie?aieie ?acoeueoaoe ianoaaeaiiy o
38 oai?eo ia a?iio?aeueio anoio ae?oae.

 Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??

Aeiiia?aeue iaoa??ae?a ?iaioe aoea c?iaeaia ia can?aeaiiyo
oiaa?enoaa aeeoy/eo e?ea??a i. Caii??aeaey oa iaeano? o 1994-1997 ??.,
Iaoe?iiaeueiiio Eiia?an? ii oai?iaai i?aai?a aeeoaiiy o i. Iineaa o
1994?., ia iaeani?e iaoeiai-i?aeoe/i?e eiioa?aioe?? o?c?ioa?aiaao?a
(i. Caii??aeaey, 1995?.), oa?eoee aei iaoiaee/iiai iin?aieea «Ioe?iea
o?ce/iiai ?icaeoeo oa noaoaaiai aeic??aaiiy ae?oae oa i?aee?oe?a
(i.Aei?i?iiao?ianuee,1997).

Ai?iaaoe?y aeena?oaoe?? a?aeaoeanue ia ni?eueiiio can?aeaii? eaoaae?
oaeoeueoaonueei? oa aini?oaeueii? iaae?ao??? Caii??cueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.

 Ioae?eaoe??

?acoeueoaoe aeena?oaoe?eii? ?iaioe aeeeaaeaii o ioae?eaoe?yo, na?aae
yeeo 3 aeo?iaeueieo noaoo? ( naiino?ei?), 3 — c ni?aaaoi?aie, 7 oac
aeiiia?aeae, 1 iaoiaee/i? ?aeiiaiaeaoe??.

 No?oeoo?a oa ianya aeena?oaoe??

Aeena?oaoe?th aeeeaaeaii ia 133 a?eooao iaoeiiieno. Aiia i?noeoue
anooi, iaeyae e?oa?aoo?e, ia’?i ? iaoiaee aeine?aeaeaiiy, ?acoeueoaoe
aeanieo niinoa?aaeaiue, caeeth/aiiy,

aeniiaee, i?aeoe/i? ?aeiiaiaeaoe??. Ia?ae?e aeei?enoaii? e?oa?aoo?e
i?noeoue 245 aeaea?ae, 70 c yeeo -eaoeiith. Aeena?oaoe?th
i?i?ethno?iaaii 7 iaethieaie, 26 oaaeeoeyie.

 INIIAIEE CI?NO ?IAIOE.

Ia’?i, iaoiaee oa iaoiaeeee aeine?aeaeaiiy. Aeey ae??oaiiy iinoaaeaieo
caaea/ o iaeaoao aea?aieia?/iiai a?aeae?eaiiy iiaeaethaaee
e?eoaaeueiee i?e?iee?iao ca aeiiiiiaith i?eeaaeo — aaia?aoi?o
ae??aiiaeenia?niiai nooiai aa?icieth iao??th oei?eaeo, aeio?eioaaee
oiiae aeey cieaeaiiy ai?noo aa?iaea?aai?a oeyoii ?aaeeiieo caoiae?a oa
o?eueo?aoe?? iia?o?y. Aeei?enoiaoaaeenue ianooii? ia?aiao?e
i?e?iee?iaoo: eiioeaio?aoe?y aa?icieth iao??th oei?eaeo 0,34 ia/ i
eoa., ?ici?? ia?aaaaeath/eo /anoie 0,3 iei, ai?no iaaaoeaii
ca?yaeaeaieo ?ii?a 10260 iae/ ni eoa..

I?ae iaoei iaaeyaeii ciaoiaeeeinue 225 oai?eo ia a?iio?aeueio anoio
(AA) ae?oae a?eii a?ae 4 aei 15 ?ie?a, ye? iaoeaee a i. Caii??aeae? oa
iaeano?. O 188 oai?eo (83,5%) anoaiiaeaii ae?aaiic aoii?/ii? oi?ie AA,
o 37 (16,5 %) — ae?aaiic ci?oaii? oi?ie AA. Aeey i?iaaaeaiiy
ii??aiyeueieo aeine?aeaeaiue ianoaaeaii 400 caei?iaeo ae?oae. I?e
ianoaaeaii? oai?iai aea/aee i?eeiyo? ee?i?/i? oa eaai?aoi?i? iieacieee.
On?i ae?oyi i?ae /an ?ai?n?? i?iaaaeai? aea?aieia?/ia ianoaaeaiiy.
Eiio?ieue ca noaiii ooieoe?? ciai?oiueiai aeeoaiiy (OCAe) cae?enithaaany
ca aeiiiiiaith ni??iiao?o o??ie «Aoii»(Aieaa??y), ii?oaoeaiiai
i?eeaaeo «Peak-Flaw-Meter» o??ie «Airmed» (Aaeeeia?eoai?y) aeey
aecia/aiiy iaeiiai ?c aeeiai?/ieo iieaciee?a OCAe — i?eiai? oaeaeeino?
aeaeeoo (IOA), yeo aeine?aeaeoaaee aeae?eueea ?ac?a ia aeiao i?ioyaii
onueiai /ano niinoa?aaeaiiy. O /anoeie ae?oae i?iaaee oano c
o?ce/iei iaaaioaaeaiiyi o e?eoaaeueiiio i?e?iee?iao? oa cae/aeiiio
na?aaeiaeu?. I?iaa i?iaiaeeeanue ia aaeia?aiiao?? i?ae /an aeeiiaiiy
aeeoeiith o?ce/ii? ?iaioe iiooaei?noth 1 ao/ea iane i?ioyaii 5 oaeeei ca
aeinyaiaiiyi ioeueno 150-170 oaea??a ca oaeeeio a eaai?aoi??? ?c
oaiia?aoo?ith iia?o?y 20-25 N, a?aeiiniith aieia?noth 50%. Oano
aaaaeaee iiceoeaiei, yeui a?aenioie iaae?iiy IOA neeaaeaa a?eueo
10 o ii??aiyii? c iieacieeaie ia?aae iaaaioaaeaiiyi (K.M.Tan,
R.T.Wall, 1985).

Aeey ii??aiyiiy nooiaith ii?ooaiiy a?iio?aeueii? i?io?aeiino? ca
iieacieeaie IOA iaie aoee aecia/ai? ooi/iai? iieacieee IOA o 383
caei?iaeo ae?oae — iaoeaioe?a i. Caii??aeaey. I?i?iaeueia ( iaaeoth/a
c? noaiii aaia?ae?ciaaii? a?iio?aeueii? iano?oeoe??) IOA iiaea aooe
aecia/aia ca ii??aiyiiyie : aeey oeii/ee?a y = 3,94x — 268, aeey
ae?a/aoie — y = 3,88x — 275, aea y -cia/aiiy IOA e/oa., x — c??no
aeeoeie o ni.

I?e?ia?ioeaiic neeciaeo aa?oi?o aeeoaeueieo oeyo?a aecia/aee
e?euee?niei iaoiaeii, ii??aithth/e ii/aoeia? aeai? c iieacieeaie,
io?eiaieie iaie o caei?iaeo ae?oae, ia ii/aoeo oa i?e e?ioe?
eiiieaenii? a?aeiiaethth/i? oa?ai?? ( E.A.Eieioeeiaa,1986). Aecia/aee
?ioiieia?/i? iieacieee ia?oiai ??aiy ca ?.A.Iao?iaei
(1982)-noaiiioeyoe?? e?ioioeeo?a o oanoao ?acaoeiooai?thaaiiy (?OE)
ca M.Jondel ?c ni?a?ia?o. (1974), oaio?e?icaeaaei? O-e?ioioeeoe
iaoiaeii A.E.*a?iooaiei ?c ni?aaao.(1983). Aoii?aeueio eaieo ?ioi?oaoo
ioe?ithaaee ca iniiaieie eeanaie ?ioiiaeiaoe?i?a A,M,G ne?iaaoee e?ia?
ca Q.Mancini (1965).

O eiiieaeniiio e?eoaaii? ae?oae, oai?eo ia AA, canoiniaoaaee aeaa
?aaeeie ia?aaoaaiiy a oiiaao e?eoaaeueiiai i?e?iee?iaoo iaeao: ia?oee
oa?aiaaoe/iee ?aaeei neeaaeaany c ia?aaoaaiiy oai?eo o aoiinoa??
aa?icieth 1 aiaeeio, ae?oaee — i?noea o nia? uiaeaiia ia?aaoaaiiy o
iaeaoao ai?iaeiaae 10 aiaeei i?ioyaii 15 ae?a.

?c o?aooaaiiyi i?eioeei?a nenoaiiino? i?aai?caoe??
iaaeeei-a?ieia?/ieo aeine?aeaeaiue (E.Aa?oieaio?,1969), aoee ?icoe?ai?
iaae? ee?i?/iiai aeine?aeaeaiiy. Aea/aee nenoaio «oai?ee ia
AA-ee?u? aeiiaoiueiai ieeo» a oiiaao e?eoaaeueiiai i?e?iee?iaoo.
Aecia/aee o ieeo iaeao ai?no aoai?io-aeieia?/iiai ia?ea?o oaeaeueiiai
caa?oaeiaiiy na?aaeiaeua ee?uaie, iaoiaeii aenieiaoaeoeaii? ??aeeiii?
o?iiaoia?ao?? ia o?iiaoia?ao? «I?e?o?ii» (I.A.?aaiueei,1991),
aeei?enoiaoth/e ye noaiaea?o aoai?i o??ie «Ia?e» (I?ia//eia) c
a?aeiieie niaeo?aeueieie oa?aeoa?enoeeaie.

I?aai?caoe?y aeine?aeaeaiue iieyaaea o ii??aiyeueiiio aea/aii?
?aiaeii?ciaaieo a?oi oai?eo, ye? io?eioaaee eiiieaenio a?aeiiaethth/o
oa?ai?th o iaeaoao c e?eoaaeueiei i?e?iee?iaoii, oa oeo, ui
ciaoiaeeeenue o iaeaoao c «ieaoeaai-i?e?iee?iaoii». Canoiniaoaaee
iaeiiiiiaioi? ii??aiyeuei? niinoa?aaeaiiy c ?enaie eiia?othaeiiai
iaoiaeo niinoa?aaeaiiy ca oai?eie. Ioe?ieo aeaieo
ee?i?ei-eaai?aoi?ieo, aeieiai-a?a??i?/ieo aeine?aeaeaiue i?iaiaeeee ca
iaoiaeaie aa??aoe?eii? noaoenoeee (A.O.Eae?i,1990).

 ?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy.

Aeey aea/aiiy aoaeoeaiino? e?eoaaeueiiai i?e?iee?iaoo iaeao oai?eo aoei
?icae?eaii ia aea? a?oie. 106 ae?oae ciaoiaeeeenue a oiiaao
e?eoaaeueiiai i?e?iee?iaoo iaeao aea?aia?aeae?eaiiy (aeine?aeia a?oia),
78 ae?oae neeaaeaee eiio?ieueio a?oio, a yeee canoiniaoaaee
«ieaoeaai-i?e?iee?iao». A?oie ae?oae aoee ?aoaeueii ?aiaeii?ciaai?.
A?eueo?noue ae?oae — 86% o aeine?aei?e a?oi? oa 87% a eiio?ieuei?e
a?oi?, no?aaeaeaee ia aoii?/io AA. Ia?aaaaeaee ae?oe c na?aaeiueiaaaeeei
ia?aa?aii caoai?thaaiiy: 70% — o aeine?aei?e a?oi? oa 67% — o a?oi?
eiio?ieth. O ia?aaaaeii? a?eueoino? ae?oae o?eaae?noue oai?iae
neeaaeaea a?eueoa ?ieo ( 79% oa 76%, a?aeiia?aeii). I?e
i?iaaaeaii? aea?aioanooaaiiy aeyaeaii, ui o ae?oae a iaio a?oiao aoea
aeniea /anoioa nainea?e?caoe?? aei aea?aai?a ee?u?a aeiiaoiueiai ieeo:
o ae?oae aeine?aeii? a?oie /anoioa nainea?e?caoe?? aei aea?aaio
ee?u?a Dermatophagoides pteronissinus -79,7% , o ae?oae eiio?ieueii?
a?oie — 85,4%. Ii?ooaiiy OCAe ca iano?oeoeaiei oeiii aoee ae?aaiinoiaai?
o an?o ae?oae iaio a?oi. IOA o ae?oae aeine?aeii? a?oie ia ii/aoeo
e?eoaaiiy neeaea 73+3%, o ae?oae eiio?ieueii? a?oie — 74+4% a?ae
iaeaaeieo cia/aiue.

O i?ioean? niinoa?aaeaiiy ca 28 oai?eie i?e canoinoaaii? ia?oiai
oa?aiaaoe/iiai ?aaeeio e?eoaaeueiiai iee?ieeeiaoo iia??oaiiy
naiiii/oooy ia aoei ca?a?no?iaaii o aeiaeiiio aeiaaeeo i? i?ioyaii 1
aiaeeie, i? o ianooii? aeae?eueea aiaeei. sse iieacaa ii??aiyeueiee
aiae?c iieaciee?a IOA, o ae?oae a aeine?aei?e a?oi? i?e??no IOA ia 15 %
oa a?eueoa o ii??aiyii? c ii/aoeiaeie cia/aiiyie a?aecia/aii o 61%
oai?eo, a oie /an , ye o eiio?ieuei?e a?oi? cia/io aaao iaee noii?ai?
oa iaaaoeai? ?acoeueoaoe — 54% (p<0,05). Ioaea, i?ioyaii aaea 1 aiaeeie ae?? aa?icieth o /anoeie ae?oae iie?auo?oueny a?iio?aeueia i?io?aei?noue. Oeae aoaeo, iiaeeeai, coiiaeaiee ?aoeaeoi?iith ae??th iaaaoeaii ca?yaeaeaieo /anoie aa?icieth, ui i?iieeathoue aeeaiei o a?iioe. Ia ianooiiiio aoai? aeine?aeaeaiiy iaie aia?oa aoea aea/aia o?eaaea ae?y e?eoaaeueiiai i?e?iee?iaoo, yea a iaai?e i??? iaaeeaea?oueny ca nai?ie oa?aeoa?enoeeaie aei i?e?iaeiiai, ia OCAe, ee?i?/iee ia?aa?a anoie o ae?oae, noai ?o ?ioiiiai noaoono. I?ae /an niinoa?aaeaiiy ca oai?eie anoaiiaeaii, ui o ae?oae aeine?aeii? a?oie IOA aaea ia 5 aeiao ?noioii ia?aaeuoaaea iieacieee o ae?oae eiio?ieueii? a?oie oa neeaaeaea, a?aeiia?aeii, 82+2% oa 79+2% (p<0,05). Ia 10 aeiao oa?ai?? iieacieee IOA o an?o ae?oae aeine?aeii? a?oie aeinyaee iaae? iaeaaeieo cia/aiue oa neeaaeaee 88+2%, iaeii/anii IOA o ae?oae eiio?ieueii? a?oie aoea ieae/ith 85% a?ae iaeaaeieo cia/aiue - 81+2% (p<0,05). Ii??aithth/e iieacieee ni??iiao??? o aeeiai?oe? a?aecia/eee, ui iie?auaiiy OCAe ia 10 aeiao oa?ai?? a?aeaoaaeinue o oai?eo iaio a?oi. I?ioa, ne?ae cacia/eoe, ui oi?niaaia aeeoo?aa ?ii?noue eaaai?a (OAE?E) neeaaeaea o ae?oae aeine?aeii? a?oie 110+12%, a o a?oi? eiio?ieth - 89+15%, oaeiae, ia'?i oi?niaaiiai aeaeeoo (IOA), yeee aei??aithaaa, a?aeiia?aeii, 105+13% oa 83+22%, aeinoia??ii a?ae??ciy?oueny (p<0,05). Ie??i oeueiai, cia/aiiy i?eiai? ia’?iii? oaeaeeino? aeaeeoo (IIO) o ae?oae aeine?aeii? a?oie (99+14%) ia?aaeuothoue iieacieee o ae?oae ?c a?oie eiio?ieth (79+26%, p<0,05). Cia/aiiy iaeneiaeueii? ia’?iii? oaeaeeino? i?ae /an aeaeeoo 25% AE?E (IIO /25), 50% AE?E (IIO/50) o ae?oae iaio a?oi oaeiae aeinoia??ii a?ae??ciyeenue, oa neeaaeaee, a?aeiia?aeii, 98+11% oa 81+24% , 92+13% oa 78+29% (p<0,05). Oaeei /eiii, o ae?oae, oai?eo ia AA, a oiiaao e?eoaaeueiiai i?e?iee?iaoo eiia??ii oaeaeoa a?aeiiaeth?oueny i?io?aei?noue ye ae??aieo oae ? aaeeeeo a?iio?a. I?iaaaeaii i?iniaeoeaiee iii?oi?eia IOA o ae?oae, ye? ia?aaoaaee a oiiaao e?eoaaeueiiai i?e?iee?iaoo iaeao ai?iaeiaae 10 aiaeei uiaeaiii i?ioyaii 15 aei?a, oa o ae?oae a oiiaao ieaoeaai-i?e?iee?iaoo aeey aecia/aiiy aeeiai?ee aeiaiaiai ?eoio IOA, yeee iaeoi/i?oa a?aeia?aaea? iayai?noue oa aeoeai?noue caiaeaiiy o a?iioao. O ia?oo aeiao ia?aaoaaiiy a iaeaoao o an?o ae?oae iieacieee IOA a?aioe? aoee ieae/a aeaiieo ?, i?aeoe/ii, ia a?ae??ciyeeny a?ae aa/??i?o, ui na?ae/eoue i?i cia/i? ii?ooaiiy OCAe. Ia 3-th aeiao oa?ai?? /?oei i?inoaaeo?oueny ia?aaeuaiiy iieaciee?a IOA aaeaiue oa aaa/a?? o ae?oae a iaeaoao c e?eoaaeueiei i?e?iee?iaoii, ia 5 aeiao o ieo a?aeiiaeth?oueny ii?iaeueiee a?ieia?/iee ?eoi. O ae?oae ?c a?oie eiio?ieth i?ney 5 aeiae niinoa?aaeaiue cia/aiiy IOA a?aenoathoue a?ae iieaciee?a ae?oae aeine?aeii? a?oie (p<0,05) ? a?ae iaeaaeieo cia/aiue, aeiaiaee ?eoi a?aeiiaeth?oueny ia 7 aeiao ia?aaoaaiiy o noaoe?iia??. I?ae /an i?iaaaeaiiy aiae?co aeeiai?ee ee?i?/ieo neiioii?a AA aeyaeee, ui o?eaae?noue aino?iai ia??iaeo o ae?oae a aeine?aei?e a?oi? neeaaeaea 6+0,3 aeiy, a o ae?oae eiio?ieueii? a?oie - 9+0,6 aeiy ( p < 0,05). Oa?i?i iaiao?aeiiai ia?aaoaaiiy o noaoe?iia?? a aeine?aei?e oa eiio?ieuei?e a?oiao oaeiae a?ae??ciyany ? neeaaeaa, a?aeiia?aeii, 19+0,6 aei?a oa 21+0,8 aeaiue (p<0,05). E??i oiai, o oai?eo i?ney ia?aaoaaiiy o e?eoaaeueiiio i?e?iee?iao? a?aenioeiaee ai?no aiceiio?e?a o e?ia? /a?ac 2 oeaei? cia/ii ciaioeany ? neeaaeaa 2,5+1,9%, ui aeinoia??ii ieae/a, i?ae o ae?oae eiio?ieueii? a?oie, o yeeo e?euee?noue aiceiio?e?a neeaaeaea 4,4+3,5% (p<0,05). Ca?aeii ?c no/anieie eiioeaioe?yie, AA aecia/aia ye o?ii?/ia caiaeueia caoai?thaaiiy aeeoaeueieo oeyo?a, i?ae /an yeiai a?aeaoaa?oueny ii?ooaiiy ?ioiiiai aiiainoaco. I?ney eo?no eiiieaenii? a?aeiiaethth/i? oa?ai?? a oiiaao e?eoaaeueiiai i?e?iee?iaoo o oai?eo a?aeaoaa?oueny aeinoia??ia ca?eueoaiiy O-noi?ani?ieo e?ioioeeo?a a?ae 15,3+1,9% aei 17,8+1,9% (p<0,05), cieaeaiiy O-oaeia?ieo e?ioioeeo?a a?ae 42,0+5,4% aei 37,1+3,8% (p<0,05) oa ca?eueoaiiy e?eueeino? ?ioiiaeiaoe?i?a G a?ae 6,18+1,16 ia/ ie aei 8,21+2,38 ia/ ie (p<0,05). Ine?eueee O-noi?ani?i? e?ioioeeoe caeaoi? aaeueioaaoe aeeth/aiiy A-e?ioioeeo?a o i?ioean ooai?aiiy aioeo?e, ?aaa?i?a, i?aeaeuaiiy e?eueeino? O-noi?ani?ieo ee?oei na?ae/eoue i?i oaiaeaioe?th aei cieaeaiiy aeoeaiino? i?ioean?a ?ioiiiai caiaeaiiy. ?noioieo ci?i iieaciee?a ?ioi?oaoo o ae?oae eiio?ieueii? a?oie ia niinoa??aaee. Ia ianooiiiio aoai? ioe?ieee iiaeeea?noue caiia?aaiiy a?iioinianoe/ii? ?aaeoe??, yea i?iaieo?oueny o ?acoeueoao? o?ce/iiai iaaaioaaeaiiy, o 17 oai?eo ia aoii?/io AA ae?oae a oiiaao e?eoaaeueiiai i?e?iee?iaoo, eio?? i?ae /an ia?aa?ao iiia?aaeiueiai oanoo c o?ce/iei iaaaioaaeaiiyi ?aaaoaaee ia iueiai cia/iei cieaeaiiyi IOA. I?e i?iaaaeaii? i?ia ?c o?ce/iei iaaaioaaeaiiyi ae?oyi a oiiaao ieaoeaai-i?e?iee?iaoo o a?eueoino? niinoa?aaeaiue(63%) ca?a?no?iaai? a?aeoai?aiiy oaiiiaio a?iio?aeueii? a?ia??aaeoeaiino?, yeee neoaoaaa ia ii/aoeo aenia?eiaioo e?eoa???i aeey a?aeai?o oai?eo. I?ae /an i?iaaaeaiiy oanoo a oiiaao e?eoaaeueiiai i?e?iee?iaoo o 82% niinoa?aaeaiue ae?oe ia ?aaaoaaee ia i?iaieaoe?eiee oano (p<0,05). Oaeei /eiii, aino?? (?aoeaeoi?i?) a?iioinianoe/i? ?aaeoe?? o ae?oae, oai?eo ia AA, o a?aeiia?aeue ia o?ce/ia iaaaioaaeaiiy ia aeieeathoue a oiiaao e?eoaaeueiiai i?e?iee?iaoo. O 85 ae?oae, oai?eo ia AA, aeyaeee aeeni?e?ia?ioeaiic neeciaeo aa?oi?o aeeoaeueieo oeyo?a i?e iaaeoiaeaeaii? aei noaoe?iia?o. Io?eiai? aeai? ii??aithaaee c iieacieeaie caei?iaeo ae?oae i. Caii??aeaey (ianoaaeaii 39 ae?oae). O ae?oae, oai?eo ia AA, i?e?ii?aai?cie ?iaeo Staphylococcus aureus aeae?eyeenue /ano?oa. I?e?ii?aai?cie o?aiceoi?ii? a?oie (iaoiaaii? oa oiiaii-iaoiaaii?) aeae?eyee o 28% oai?eo ia AA, oa o 15% a a?oi? caei?iaeo ae?oae. E?euee?noue i?e?iaieo o?e o 1 ie i?e oeueiio neeaaeaea 10 - 10 EIA/ie. A?eae ?iaeo Candida albicans o oai?eo ia AA aeae?eai? o 15 (18%) ae?oae, e?euee?noue i?e?iaieo o?e a ie aoea 10 - 10 EIA/ie. A a?oi? caei?iaeo ae?oae a?eae ?iaeo Candida aeae?eai? o 3 ( 3%) , e?euee?noue i?e?iaieo o?e neeaaeaei 10 EIA/ie. Io?eiai? iaie iieacieee, ye? oa?aeoa?ecothoue oaeoeueoaoeaio oa o?aiceoi?io a?oie i?e?ii?aai?ci?a, ca?aathoueny ?c aeaieie E.A.Eieio?eiai? (1986) oa E.E.Eaoiniai? (1986). Aeyaeee, ui o 60 oai?eo ae?oae ?c iienaieie iciaeaie aeena?ico neeciaeo iaieiiie, ye? ciaoiaeeeenue o iaeaoao ?c e?eoaaeueiei i?e?iee?iaoii, i?ae /an aeeiai?/iiai ianoaaeaiiy /a?ac 15 aei?a ciaioeeanue /anoioa aeae?eaiiy i?e?ii?aai?ci?a oaeoeueoaoeaii? oa o?aiceoi?ii? a?oi. I?e?ii?aai?cie oaeoeueoaoeaii? a?oie aeae?eai? o 50,0+6,5% ae?oae i?ae /an ia?oiai ianoaaeaiiy, a i?e iiaoi?iiio - o 27,0+6,4% ae?oae (p<0,05). *anoioa aeae?eaiiy i?e?ii?aai?ci?a o?aiceoi?ii? a?oie neeaaeaea 36,0+6,9% ia ii/aoeo e?eoaaiiy oa 15,0+5,2% /a?ac 15 aei?a eiai i?iaaaeaiiy (p<0,05). Ciaioeeanue /anoioa aeae?eaiiy i?e?ii?aai?ci?a ?iaeo Staphylococcus aureus a?ae 28% aei 10%, a oaeiae e?euee?noue ae?oae-iin??a Candida albicans: a?ae 13 (22%) i?ae /an iaaeoiaeaeaiiy aei 7 (14%) ae?oae iai?ee?ioe? oa?ai??. O ae?oae eiio?ieueii? a?oie ia noaeiny ci?i, ? i?e iiaoi?iiio ianoaaeaii? oaeiae caa??aaeenue yaeua aeena?ico neeciaeo. Oaeei /eiii, io?eiai? iaie aeai? na?ae/aoue i?i a?aeiiaeaiiy i?e?ia?ioeaiico neeciaeo aa?oi?o aeeoaeueieo oeyo?a o oai?eo ia AA i?ney eiiieaenii? a?aeiiaethth/i? oa?ai?? o iaeaoao c e?eoaaeueiei i?e?iee?iaoii. Aea/aee nenoaio "oai?ee ia a?iio?aeueio anoio -e?ea?iyi? iaeaoe-ee?u? ieeo", iie?ath/enue ia aeina?ae aeine?aeaeaiue, i?iaaaeaieo ia eaoaae?? oaeoeueoaonueei? iaae?ao??? CIO, i?i ?ieue i??iae?o?ae?a ye iniiaieo aeiiaoiaai?a o aeieeiaii? aoii?/ii? AA ( I.I.Nao?iiiaa,1990, I.A.?aaiueei,1993, TH.A.Eioeiaa,1995). Iii?oi?eia ee?u?a o iiaooiaiio ieeo, ia aeoieo aaaaoueio aeine?aeiee?a, ? aaaeeeaei a i?aai?caoe?? e?eoaaiiy oai?eo ia AA (I. A.?aaiueei c ni?aaao., 1995, S.J.Tkachyk, 1995). Ie ia cono??ee a e?oa?aoo?? aeaieo i?i ai?no ee?u?a iiaooiaiai ieeo o i?ei?uaiiyo niae?ie?ea?aiue, o aaeieaia?ao, ye?, aacnoii?aii, aeeeeeathoue oe?eaa?noue aeey i?aeoe/ii? aea?aieia??. I?eionoeee, ui o?eaaeee aieea ae??aiiaeenia?niiai nooiai ?ii?ciaaiiai aa?icieth iao??th oei?eaeo oa iino?eii? o?eueo?aoe?? iia?o?y caeaoi? aieeaaoe ia /enaeuei?noue oa a?ieia?/io aeoeai?noue ee?u?a iiaooiaiai ieeo o i?ei?uaiiyo. A?ae/ooia i?enooi?noue ee?u?a o iaeaoao aea?aia?aeae?eaiiy (iia'ycai?, eiia??ii, ?c caiinii ?o c inaeue oai?eo) a?aecia/ai? o ceiiaee ia??iae. O e?oi?e ia??iae aea?ieia?/ia neooaoe?y aeaui iie?auo?oueny. sse iieacaee iao? niinoa?aaeaiiy, o iaeaoao c e?eoaaeueiei i?e?iee?iaoii aoaeoeai?noue i?ioeee?uiaeo caoiae?a i?aeaeuo?oueny. O oeeo iaeaoao caa?oaeiaiiy ee?uaie aoea o 2,4 ?ace ieae/ith, i?ae o eiio?ieueieo. O ieeo oeeo iaeao eiioeaio?aoe?y aoai?io neeaaeaea 0,345+0,085 ia/ a iniiae ia ii/aoeo aeine?aeo oa 0,05+0,001 ia/ a iai?ee?ioe? (p<0,05). Aeinyaiaii? ??ai? eiioai?iaoe?? i?ei?uaiue ieae/? iaea?eueo aeiionoeiiai ??aiy o 10 ?ac?a ? a?aeiia?aeathoue i?enooiino? iiiaeeiieeo in?a ee?u?a ?c ?ic?aooieo ia 1 a ieeo i?ioyaii /ano aaaaoaoe??. O ieeo eiio?ieueieo iaeao ai?no aoai?io cieceany a?ae 0,363+0,100 ia/ a iniiae aei 0,120+0,033 ia/ a. Oaeei /eiii aoaeoeai?noue a?a??i?/ieo cania?a aoea iaiiaiith (p<0,05). Onoaiiaeee, ui aeei?enoiaaiee iaie o?eueo? caeaoiee cao?eioaaoe o ieeo /anoee aa?iieaieoiio ?ici??ii 8 iei, a oaeiae oaeaeuei? eoeueee ee?u?a ?iaeo Dermatophagoideus, ui i?aeoaa?aeaeo?oueny eiioeaio?aoe??th aoai?io o ieeo ia o?eueo?? - aei 0,4 ia/ a iniiae, yea ia?aaeuo? ai?no aoai?io o ieeo iaeao- 0,05 ia/ a iai?ee?ioe? aeine?aeaeaiiy. Oaeei /eiii, a i?aai?ciaaieo i?ei?uaiiyo-iaeaoao aea?aia?aeae?eaiiy c e?eoaaeueiei i?e?iee?iaoii aeinyaa?oueny ni?eyoeeaa aea?ieia?/ia neooaoe?y, yea ni?ey? naiiaaiaco aoii?/ii? AA. Aiae?c a?aeaeaeaieo ?acoeueoao?a eiiieaenii? oa?ai?? a oiiaao e?eoaaeueiiai i?e?iee?iaoo iieacaa, ui o ae?oae aeine?aeii? a?oie e?euee?noue caaino?aiue ia ??e aoea iaioith, i?ae o ae?oae ?c a?oie eiio?ieth ? neeaaeaea, a?aeiia?aeii, 3,1+0,8 oa 5,6+1,1 (p<0,05). O oai?eo i?ney oa?ai?? o iaeaoao c e?eoaaeueiei i?e?iee?iaoii o 3 ?ace ??aeoa niinoa??aaeenue iaiaaee yaeooe, ye? iio?aaoaaee aini?oae?caoe??, o 2 ?ace ??aeoa - eaae? iaiaaee yaeooe, o ii??aiyii? c ae?oueie a?oie eiio?ieth. Iaiao?aei?noue o canoinoaaii? b-aaii?no?a aoea iaioith o ae?oae aeine?aeii? a?oie ? neeaaeaea, a?aeiia?aeii, 2,3+0,7 ?iaaeyoe?e ia oeaeaeaiue oa 5,2+1,5 ?iaaeyoe?e ia oeaeaeaiue a eiio?ieuei?e a?oi? (p<0,05). O 72,2% ae?oae aeine?aeii? a?oie a?aecia/aia no?eea ?ai?n?y caoai?thaaiiy ai?iaeiaae 6 i?nyoe?a oa a?eueoa. E?euee?noue oai?eo eiio?ieueii? a?oie c o?eaae?noth ?ai?n?? 6 i?nyoe?a aoea o 2 ?ace iaioith (p<0,05). Oaeei /eiii, aiae?c aaciina?aaei?o oa a?aeaeaeaieo ?acoeueoao?a aeine?aeaeaiue iieacaa aoaeoeai?noue eiiieaenii? a?aeiiaethaaeueii? oa?ai?? ae?oae, oai?eo ia AA, o iaeaoao c e?eoaaeueiei i?e?iee?iaoii c iecueeith caa?oaeiai?noth aea?aaiaie ee?u?a iiaooiaiai ieeo, ui i?iyaey?oueny a?eueo oaeaeeei a?aeiiaeaiiyi a?iio?aeueii? i?io?aeiino?, ee?i?/iei iie?auaiiyi, ii?iae?caoe??th i?e?ia?ioeaiico neeciaeo aa?oi?o aeeoaeueieo oeyo?a, no?ee?noth aeinyaiaiiai oa?aiaaoe/iiai aoaeoo o aeaeyae? ciaioaiiy /anoioe caaino?aiue oai?iae, ca?eueoaiiy o?eaaeino? ?ai?n??, ciaioaiiy niiaeeaaiiy e?e?a. Ia i?aenoaa? aeua neacaiiai, iiaeeeai c?iaeoe aeniiaie, ui iinoaaeai? caaea/? aeine?aeaeaiue aeeiiai?, c?iaeai? oae? aeniiaee:  AENIIAEE 1.O?eaaea ia?aaoaaiiy ae?oae, oai?eo ia AA, a iaeaoao c e?eoaaeueiei i?e?iee?iaoii aeeeeea? ii?iae?caoe?th a?iio?aeueii? i?io?aeiino? ia 10 aeiao, a?aeiiaeth? aeiaia? a?i?eoie IOA ia 5 aeiao oa?ai??. 2. E?eoaaeueiee i?e?iee?iao iaeao i?aeaeuo? oiea?aioi?noue oai?eo ia AA aei o?ce/iiai iaaaioaaeaiiy. 3. Aeei?enoaiiy o eiiieaeni?e a?aeiiaethaaeuei?e oa?ai?? e?eoaaeueiiai i?e?iee?iaoo ii?iae?co? i?e?ia?ioeaiic neeciaeo aa?oi?o aeeoaeueieo oeyo?a o ae?oae, oai?eo ia AA. 4. Anoaiiaeaii, ui ca aeiiiiiaith iino?eii? o?eueo?aoe?? iia?o?y oa iane/aiiy eiai ae??aiiaeenia?niei ?ii?ciaaiei aa?icieai iao??th oei?eaeo iiaeeeai aoaeoeaii cieceoe caa?oaeiaiiy iaeao aea?aiaaiieie i?iaeoeoaie aeeoo?ae?yeueiino? ee?u?a iiaooiaiai ieeo aei ne?aeiaeo eiioeaio?aoe?e - 0,05 ia/ a, ui a 10 ?ac?a ieae/a i?eionoeieo eiioeaio?aoe?e. 5. ?ic?iaeai iioeiaeueiee ?aaeei aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo ( nooiai ?ii?ciaaiiai ae??aiiaeenia?niiai aa?icieth iao??th oei?eaeo oa o?eueo?aoe?? iia?o?y) - uiaeaiia 10 aiaeeiia ia?aaoaaiiy oai?eo o iaeaoao i?ioyaii 15 ae?a. 6. Aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo o a?aeiiaethaaeuei?e oa?ai?? ae?oae, oai?eo ia AA, ni?ey? a?eueo oaeaee?e ?aa?an?? neiioii?a caoai?thaaiiy oa ciaioaiith oa?i?io ia?aaoaaiiy o noaoe?iia?? ia 3 aeiae (p<0,05), iie?ioaiith a?aeaeaeaieo ?acoeueoao?a: ciaioaiith /anoioe iaiaae?a yaeooe a 3 ?ace, o ia?aaaaeii? a?eueoino? oai?eo (72,7%) o?eaae?noue ?ai?n?? aeinyaaea a?eueo i?ae 6 i?nyoe?a.  NIENIE I?AOeUe, ssE? IAAe?OEIAAI? CA OAIITH AeENA?OAOe?? 1.Nieiaeiaa E.A. I?aai?caoe?y iaeao n ea/aaiui iee?ieeeiaoii aeey oa?aiee aeaoae, aieueiuo a?iioeaeueiie anoiie // Oe?a?inueeee ioeueiiiieia?/iee aeo?iae.- 1997.- N 4.- C. 52-53 2.Nieiaeiaa E.A. Aieea ae??aiiaeenia?niiai ?ii?ciaaiiai no- oiai aa?icieth iao??y oei?eaeo ia noai a?iio?aeueii? i?io?aeiino? o ae?oae, oai?eo ia a?iio?aeueio anoio // Iaaee/ia ?aaa?e?oaoe?y, eo?i?oieia?y ? o?c?ioa?ai?y.- 1998.- N 2.- N.22-23 3.Nieiaeiaa E.A. Aea?ieiae/aneee iiieoi?eia a aeea?aieiae/aneii ioaeaeaiee // A?niee i?iaeai a?ieia?? ? iaaeeoeeie.1998.- N 15.- N. 41 - 43. 4.Nieiaeiaa E.A., Aiy?neay E.I., Iaaeaeueneay N.I., Oa?anaae/ O.A., Eioeiaa TH.A., Eiaa/aaa O.A. Iee?iaeioeaiic neecenouo aa?oieo aeuoaoaeueiuo iooae o aeaoae, aieueiuo a?iioeaeueiie anoiie , a oneiaeyo ea/aaiiai iee?ieeeiaoa // Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee ? i?aeoeee.: Ca. iaoe.noaoae, aei.2, o.2.- Caii??aeaey, 1998. - N.207 - 209 5.TH.A.Eioeiaa, E.I.Aiy?nueea, E.?.Eeyoeueea, I.A.E?c?ia, A.?.Iaco?,A.A.Ie?iiaiei, N.I.Iaae?euenueea, ?.A.Nieiaeiaa Aoaeoeai?noue niaoe?o?/ii? ?ioiioa?ai?? aea?aaiaie ee?u?a iiaooiaiai ieeo o oai?eo ia aoii?/io a?iio?aeueio anoio ae?oae.//Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee ? i?aeoeee.: Ca. iaoe.noaoae, aei.2, o.2.- Caii??aeaey, 1998. - N.248-250 6.Eaaiueei I.A., Eioeiaa TH.A., Nieiaeiaa E.A. Iniaaiiinoe yeieiaee e eeeieei-aeaeaie/aneia cia/aiea eeauae aeiiaoiae iuee // Caii?iaeuea,1994.-322n.- Aeaeeia?.: 97 iaca.-Oe?.- Aeai. a AIOA Oe?aeiu, 16.02.1995.- N 387- Oe95.- AeI? AEIEOE.-1995.- N 6.- N.283. 7. Eaaiueei I.A., Eioeiaa TH.A., Nieiaeiaa E.A. Ninoaa iuee aeeeeu e ?ene ay?inaineaeeecaoeee i?e a?iioeaeueiie anoia o aeaoae//Ioeueiiiieiaey.- I?eeiaeaiea 4, Iaoa?eaeu III Iaoeeiiaeueiiai Eiia?anna ii aieaciyi i?aaiia aeuoaiey .- Naieo-Iaoa?ao?a, 1992.- N 214 8.Eaaiueei I.A., Nieiaeiaa E.A., Iaaeaeueneay N.I. Iaeei- aeenia?niue eiiece?iaaiiue nooie ay?icieue iao?ey oei?eaea a ea/aiee aeaoae, aieueiuo a?iioeaeueiie anoiie // Aeooaeueiua i?iaeaiu a iaaeeao?ee: Na. iao/.o?oaeia.-Caii?iaeuea,1995. - N. 129-130 9.Eaaiueei I.A., Nieiaeiaa E.A., Eiaa/aaa O.A. Aeaeiaia ?ac- iiia?acea iee?ioei?u aa?oieo aeuoaoaeueiuo iooae o caei?iauo e aeaoae, aieueiuo a?iioeaeueiie anoiie, a oneiaeyo e?oiiiai i?iiuoeaiiiai ai?iaea // Aeooaeueiua i?iaeaiu a iaaeeao?ee: Na. iao/.o?oaeia.- Caii?iaeuea, 1995.- N.128 10.?aaiueei I.A., Nieiaeiaa ?.A., Iaae?euenueea N.I. Aecia/aiiy iaeneiaeueiiai aeni??aoi?iiai iioieo a iii?oi?oaaii? ooieoe?iiaeueiiai noaio eaaaiue o ae?oae. // ?aaa?e?oaoe?y a iaae?ao???: Ca. iaoe. i?aoeue.- A?iieoey, 1995.- N.36-37 11.?aaiueei I.A., Nieiaeiaa E.A., Iaaeaeueneay N.I. Nooi/iua aei?eoiu a?iioeaeueiie i?ioiaeeiinoe o aeaoae a iiiauaieyo n eiio?iee?oaiui iee?ieeeiaoii.// Aeooaeueiua aii?inu ooeceao?ee, ioeueiiiieiaee : Na. noaoae, aui.2.- Caii?iaeuea, 1997.- N.21-22 12.Eioeiaa TH.A.,Aiy?nueea E.I., Ie?iiaiei A.A.,Nieiaeiaa ?.A. Aeina?ae aea?ieia?/iiai eiio?ieth aea?aieia?/ieo e?ea?aiue Caea?iaooy // Iaoa??aee iaoeiaeo i?oeue ?? c'?caeo oo?c?ao??a ? ioeueiiiieia?a Oe?a?ie, Ee?a,1998.- N.237, N 568. 13.Nieiaeiaa E.A., Eioeiaa TH.A.,Iaaeaeueneay N.I., Ie?iiaiei A.A. Caa?yciaiiinoue iiiauaiee eeauaie Dermatophagoides a oneiaeyo ea/aaiiai iee?ieeeiaoa.// Iaoa??aee iaoeiaeo i?oeue ?? c'?caeo oo?c?ao??a ? ioeueiiiieia?a Oe?a?ie, Ee?a,1998.- N.238, N 571. Iaoiaee/aneea ?aeiiaiaeaoeee: 10. Ioe?iea o?ce/iiai ?icaeoeo oa noaoaaiai aeic??aaiiy ae?oae oa i?aee?oe?a: Iaoiae.?aeiiaiae./ Neeaae. E.A.Aauaiei, A.I.Eiiae?aoue?a, E.I.Aaaeiaeia, I.A.?aaiueei, ?.A.Nieiaeiaa.Aei?i?iiao?ianuee,1997. - 15 n. AIIOAOe?ss. Aeena?oaoe?y i?enay/aia aea/aiith aoaeoeaiino? e?eoaaeueiiai i?e?iee?iaoo iiaeeo?eiaaieo iaeao aea?aia?aeae?eaiiy (ae??aiiaeenia?niee ?ii?ciaaiee aa?icieue iao??th oei?eaeo c iino?eiith o?eueo?aoe??th iia?o?y). Aeiaaaeaii, ui aia?oa aeei?enoiaaiee 10 aiaeeiiee ?aaeei ia?aaoaaiiy ae?oae, oai?eo ia AA, a oiiaao e?eoaaeueiiai i?e?iee?iaoo i?ioyaii 15 aei?a, caeaoiee iie?iooaaoe ye aaciina?aaei?, oae ? a?aeaeaeai? ?acoeueoaoe oa?ai??: a?iio?aeueia i?io?aei?noue a?aeiiaeth?oueny ia 10 aeaiue, aeiaia? ?? a?i?eoie - ia 5 aeaiue, ii?iae?co?oueny i?e?ia?ioeaiic neeciaeo aa?oi?o aeeoaeueieo oeyo?a, ?icaeaa?oueny oiea?aioi?noue aei o?ce/iiai iaaaioaaeaiiy, o 72,7% oai?eo o?eaae?noue ?ai?n?? a?eueo i?ae 6 i?n. A iaeaoao caa?oaeiaiiy i?iaeoeoaie aeeoo?ae?yeueiino? ee?u?a iiaooiaiai ieeo ciaioo?oueny aei ne?aeiaeo eiioeaio?aoe?e (0,05 ia/ a iniiae). AIIIOAOeEss. Aeenna?oaoeey iinayuaia eco/aieth yooaeoeaiinoe ea/aaiiai iee?ieeeiaoa iiaeeoeoee?iaaiiuo iaeao aeea?aieiae/aneiai ioaeaeaiey (iaeeiaeenia?niue nooie eiiece?iaaiiue ay?icieue iao?ey oei?eaea n iinoiyiiie oeeueo?aoeeae aicaeooa). Ea/aaiue iee?ieeeiao iiaeaee?iaaee n iiiiuueth i?eai?a - aaia?aoi?a nooiai eiiece?iaaiiiai iaeeiaeenia?niiai ay?iciey iao?ey oei?eaea. A yoeo aea iaeaoao niaethaeaeenue oneiaey aeey nieaeaiey niaea?aeaiey ay?iaeea?aaiia iooai ?aaeeiiuo ia?ii?eyoee e oeeueo?aoeee aicaeooa. Eniieueciaaeenue neaaeothuea ia?aiao?u iee?ieeeiaoa: eiioeaio?aoeey ay?iciey iao?ey oei?eaea 0,34 ia/i eoa., ?acia? i?aiaeaaeathueo /anoeoe 0,3 iei, niaea?aeaiea io?eoeaoaeueiuo eiiia 10260 aae./ni eoa. Iiae iaoei iaaethaeaieai iaoiaeeeinue 225 aeaoae, aieueiuo a?iioeaeueiie anoiie, a aic?anoa io 4 aei 15 eao, i?iaeeaathueo a a. Caii?iaeuea e iaeanoe. Ianeaaeiaaii 400 caei?iauo aeaoae. Onoaiiaeaiu ii?iaeueiua iieacaoaee ieeiaie nei?inoe auaeioa (INA) o aeaoae - aeeoaeae a. Caii?iaeuey e o?aaiaiea aeey iiaen/aoa INA a caaeneiinoe io iiea e aic?anoa. Ieieiaeueiay (iia?aie/iay n ninoiyieai aaia?aeeciaaiiie a?iioiiano?oeoeee) INA iiaeao auoue ii?aaeaeaia ii oi?ioeai: aeey iaeue/eeia o = 3,94x-268 , aeey aeaai/ae y = 3,88x-275, aaea o - cia/aiea ieeiaie nei?inoe auaeioa a e/iei., o - ?ino ?aaaiea a ni. Aeieacaii, /oi aia?aua eniieueciaaiiue 10-/aniaue ?aaeei i?aauaaiey aeaoae, aieueiuo a?iioeaeueiie anoiie, a oneiaeyo ea/aaiiai iee?ieeeiaoa a oa/aiea 15 aeiae niiniaai oeo/oaoue eae iaiin?aaenoaaiiua, oae e ioaeaeaiiua ?acoeueoaou oa?aiee: a?iioeaeueiay i?ioiaeeiinoue ainnoaiaaeeaaaony ia 10 aeaiue, nooi/iua aa aei?eoiu - ia 5 aeaiue, ii?iaeecoaony iee?iaeioeaiic neecenouo aeuoaoaeueiuo iooae (oiaiueoeeanue /anoioa auaeaeaiey iee?ii?aaieciia ?iaea Staphylococus aureus n 28% aei 10%) , ?acaeaaaony oiea?aioiinoue e oece/aneie iaa?ocea. Aeeeoaeueiinoue ino?iai ia?eiaea e iaiaoiaeeiue n?ie i?aauaaiey aieueiiai ?aaaiea a oneiaeyo noaoeeiia?a i?e eniieueciaaiee ea/aaiiai iee?ieeeiaoa nie?auaaony ia 3 aeiy. Iinea eo?na ainnoaiiaeoaeueiie oa?aiee a oneiaeyo ea/aaiiai iee?ieeeiaoa o aieueiuo i?ienoiaeeo aeinoiaa?iia oaaee/aiea O-noi?anni?iuo eeioioeeoia, /oi naeaeaoaeuenoaoao i oaiaeaioeee e nieaeaieth aeoeaiinoe i?ioeannia eiioiiiai ainiaeaiey. O 72,7 % aieueiuo aeeeoaeueiinoue ?aiennee ninoaaeea aieaa 6 ian. A iaeaoao a oneiaeyo ea/aaiiai iee?ieeeiaoa caa?yciaiiinoue i?iaeoeoaie aeeciaaeayoaeueiinoe eeauae auoiaie iuee nieaeaaony aei neaaeiauo eiioeaio?aoeee -0,05 ia/a iniiau (enneaaeiaaii niaea?aeaiea aoaieia a iuee iaeao iaoiaeii aunieiyooaeoeaiie aeeaeeinoiie o?iiaoia?aoee). Onoaiiaeee, /oi eniieuecoaiue iaie oeeueo? niiniaai caaea?aeeaaoue a iuee /anoeoeu ay?iieaieoiia ?acia?ii 8 iei (a oii /enea oaeaeueiua oa?eee eeauae Dermatophagoides). Iniiaiua ?acoeueoaou ?aaiou iaoee i?eiaiaiea a ea/aaii-i?ioeeaeoe/aneeo e naiaoi?iuo o/?aaeaeaieyo. ANNOTATION. The work establishes the effectiveness of therapy and rehabilitation of children having bronchial asthma using medical microclimate (small-dispersed dry ionised aerosol of NaCl with the air filtration). It was proved, that the first-time used 10-houd regimen of children's suffering from bronchial asthma stay in the conditions of curative microclimate during 15 days may improve both the direct and the distant results of therapy. Thus, the bronchial passage restores in the 10-th day, its circad biorhythms restore on the 5-th day, microbiocenosis of respiratory tract mucous membrane normalises, tolerance to physical exercise develops, the remission period was over 6 months in 72,2 % of cases. The pollution by the products of Dermatophagoides life in the buildings decreases to the tvace-concentrations (0,05 mg/g of base).

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