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Лікувальний мікроклімат спеціалізованих палат в комплексній терапії дітей, хворих на бронхіальну астму: Автореф. дис… канд. мед. наук / І.В. Солодов

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OE?A?INUeEEE IAOEIAI-AeINE?AeIEE

?INOEOOO IAAeE*II? ?AAA?E?OAOe?? OA

EO?I?OIEIA?? IIC OE?A?IE

NIEIAeIAA ??EIA AANEE?AIA

OAeE 616.248-053.2-085:628.8

“ E?EOAAEUeIEE I?E?IEE?IAO

NIAOe?AE?CIAAIEO IAEAO A

EIIIEAENI?E OA?AI?? Ae?OAE,

OAI?EO IA A?IIO?AEUeIO ANOIO ”

14.01.33 – eo?i?oieia?y oa o?c?ioa?ai?y

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa
iaaee/ieo iaoe

Iaeana – 1999

Aeena?oaoe?y ? ?oeiien.

?iaioa aeeiiaia a Caii??cueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

i?ioani? ?aaiueei Ieaa A?eai?iae/

Caii??cueeee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e oaeoeueoaonueei? iaae?ao???

(c 1997 ?. i?aoeth? ii eiio?aeoo a E?a??)

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani?

Coaa?aiei ?ai? Eaii?aeiae/,

Oe?a?inueeee IAe? iaaee/ii? ?aaa?e?oaoe?? oa eo?i?oieia??,

caa?aeoaa/ a?aeae?eaiiyi caoai?thaaiue ae?oae oa i?aee?oe?a,

aeieoi? iaaee/ieo iaoe, i?ioani?

Aaa?e ?ai? Eaii?aeiae/,

Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e i?iiaaeaaoeee aeeoy/eo oai?ia

I?ia?aeia onoaiiaa:

Oe?a?inueeee IAe? aeeoy/i? eo?i?oieia?? oa o?c?ioa?ai?? IIC Oe?a?ie,
a?aeae?e iaaee/ii? ?aaa?e?oaoe?? ae?oae, i. ?aiaoi??y

Caoeno a?aeaoaeaoueny “ 19 ” ethoiai 1999 ?ieo i 13 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 41.608.01 Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo iaaee/ii? ?aaa?e?oaoe?? oa eo?i?oieia??
IIC Oe?a?ie.

Aae?ana: 270014, i. Iaeana, Ea?iiioianueeee i?ia. 6.

Aaoi?aoa?ao ?ic?neaiee “ 17 ” n?/iy 1999 ?ieo.

A/aiee nae?aoa? niaoe?ae?ciaaii?

a/aii? ?aaee, eaiaeeaeao iaaee/ieo iaoe,

noa?oee iaoeiaee ni?a?ia?oiee
Aei?o???aa A.I.

 CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE.

Aeooaeuei?noue i?iaeaie. Ca inoaii? ?iee a on?o e?a?iao na?oo
a?aecia/a?oueny c?inoaiiy /enea oai?eo aea?a?/ieie caoai?thaaiiyie (
A.I.Iooeee, 1994, TH.A.Aaeueo?uaa, 1995, I.?.Eaneoey, 1996, I.Wetztman,
1995). Aeniea caoai?thaai?noue aei?ineeo oa ae?oae ia a?iio?aeueio
anoio iia’ycaia oaeiae ? c i?aeaeuaiiyi caa?oaeiaiiy iia?o?yiiai
na?aaeiaeua. Iaeiei ?c oaeoi??a naiiaaiaco anoie iiaea aooe
i?eieiaiiy ae?? ia neeciao iaieiieo a?iio?a i?e/eiiicia/oueo
aea?aai?a oa ?ioeo iiae?acithth/eo ?a/iaei (A.A.*o/ae?i, 1992,
A.I.Wardlaw,1993).

O ca’yceo c oeei no/ani? i?aeia?iaei? eiioeaioe?? oa?ai??
a?iio?aeueii? anoie i?aee?aneththoue iaiao?aei?noue iie?auaiiy
iaaeieeoiueiai na?aaeiaeua (Aaoanaea, 1992).

Niae?ioa?ai?y, yea c oni?oii aeei?enoiao?oueny a e?eoaaii? a?iio?aeueii?
anoie ? i??i?eoaoiei iai?yieii oe?a?inueei? oeiee aea?aieia?a ?
ioeueiiiieia?a, ii?aeio? a nia? aieea iaea?eueo /enoi? a?ae
aea?aai?a ? i?e?ii?aai?ci?a aoiinoa?e oaoo nieueiaeo ae?ia?oie c
iino?eiith oaiia?aoo?ith ? aieia?noth iia?o?y oa i?ioecaiaeueiee
aoaeo ?ii?ciaaiiai aa?icieth iao??th oei?eaeo ( I.Ae.Oi?ioo?i,,1987,
?.N. Eaiei, 1989, TH.I.Neieeiiea, 1989,, E.E. ?o?iiaa, 1993, A. A?eae,
1994, P.Krasko et.al., 1983, I.Mohapl et.al., 1991 ).

Iaeiae, oe?iea canoinoaaiiy niae?ioa?ai?? iaiaaeo?oueny
oa?eoi??aeueieie oa ?ioeie ianoaaeiaie. A iao /an oe?iei
aeei?enoiaothoueny ??ciiiai?oi? i?eeaaee, caeaoi? /anoeiai iiaeaethaaoe
i?e?iee?iao nieueiaeo oaoo ( I.Ae.Oi?ioo?i, 1990, A.I.Neaeaeueieeia c
ni?aaao., 1989, I.I.Ai?aaiei, 1991). Aeey i/euaiiy iia?o?y
i?ei?uaiue a?ae aea?aai?a canoiniaothoue ??ci? iia?o?yiii/eni?
iaeaaeiaiiy ( I.N. Aaneeue?aa c ni?aaao., 1995, I.A. *o/ae?i, 1995,
M.H. Schata, 1993 ).

Aieiaiith oaiaeaioe??th uiaei oaeineiiaeaiiy iaoiae?a aaeioa?ai??
(e?eoaaiiy nooei aa?icieai iao??th oei?eaeo)? iaea?aeaiiy iiaeeeaino?
?aaoethaaoe ia?aiao?e i?e?iee?iaoo oa i?aeo?eioaaoe ?o o?eaaeee /an,
iaaeeaeath/e ?o aei aoiinoa?e o i?e?iaeieo nieueiaeo oaooao.

Iioeiaeueiei ?aaeeiii oa?ai?? ii?aeiaiiy iino?eiiai i/euaiiy iia?o?y
oa o?eaaei? i?aeo?eiee e?eoaaeueiiai ?ii?ciaaiiai aa?icieth iao??th
oei?eaeo c oa?aeoa?enoeeaie, ui iaaeeaeathoueny aei i?e?iee?iaoo
i?ei?uaiue o nieyieo ae?ia?oeao. Aaaeaiei aaoiiiii?noue i?eeaaeo aeey
noai?aiiy i?e?iee?iaoo oa iiaeeea?noue eiai ia?anoaaiiy.

Ca aeiiiiiaith noai?aiiai iiaiai i?eeaaeo, ?ic?iaeaiiai caii??cueeeie
a/aieie oa oaoi?eaie (aaoi?nueea iina?ae/aiiy i?i aeiao?ae N 1748328 SY
an.II-AI (1990) A.A.Eooa?iaa oa iiceoeaiiai ??oaiiy eii?oaoo ii iia?e
iaaee/i?e oaoi?oe? Oe?a?ie (i?ioieie N 4 a?ae 2 eeiiy 1991?.)), ?
iiaeeeaei noai?aiiy e?eoaaeueiiai i?e?iee?iaoo c eiio?ieueiaaieie
ia?aiao?aie aaciina?aaeiuei a iaeaoao a?aeae?eaiue. Oea iiaea a?aee?eoe
iia? ia?niaeoeae a e?eoaaii? a?iio?aeueii? anoie. Aea oa?aiaaoe/i?
iiaeeeaino? aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo a eiiieaeniiio
e?eoaaii? oai?eo ae?oae a oiiaao cae/aeieo iaeao aea?aieia?/iiai
a?aeae?eaiiy ia iao /an aea/ai? iaaeinoaoiuei, ui iio?aao? aecia/aiiy
aoaeoeaiino? ae?? i?e?iee?iaoo, ui noai?th?oueny , c ianooiiith
?ic?iaeith iioeiaeueieo (aoaeoeaieo) ?aaeei?a oa?ai??.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, oaiaie. Ia?aiee iai?yiie
aeine?aeaeaiue o?nii iia’ycaiee c IAe?, ye? cae?enithaaeenue a
Caii??cueeiio iaaee/iiio oi?aa?neoao? ia eaoaae?? oaeoeueoaonueei?
iaae?ao??? ? i?enay/ai? ?ic?iaoe? i?iaeaie ??cieo iaoiae?a e?eoaaiiy
oai?eo ia aoii?/io a?iio?aeueio anoio

( N aea?ae?a?no?aoe?? 0194 U 008431, 0197 U 001354 )

Iaoith  aeine?aeaeaiiy ?ic?iaea cania?a eiiieaenii? a?aeiiaethaaii?
oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c aeei?enoaiiyi
o?eaaeiai ia?aaoaaiiy a iaeaoao c e?eoaaeueiei i?e?iee?iaoii (
ae??aiiaeenia?niee ?ii?ciaaiee nooee aa?icieue iao??th oei?eaeo c
iino?eiith o?eueo?aoe??th iia?o?y).

 Caaaeaiiy aeine?aeaeaiiy

1. Aea/eoe noai a?iio?aeueii? i?io?aeiino?, aeiaiaeo a?i?eoi?a i?eiai?
oaeaeeino? aeaeeoo o oai?eo ia a?iio?aeueio anoio ae?oae a oiiaao
o?eaaeiai aieeao e?eoaaeueiiai i?e?iee?iaoo niaoe?ae?ciaaieo iaeao.

2. Anoaiiaeoe aieea e?eoaaeueiiai i?e?iee?iaoo iaeao ia
a?ia??aaeoeai?noue a?iio?a i?e o?ce/iiio iaaaioaaeaii?, noai
i?e?ia?ioeaiico neeciaeo iaieiiie aa?oi?o aeeoaeueieo oeyo?a.

3. Aea/eoe iieacieee caa?oaeiaiiy iaeao c e?eoaaeueiei
i?e?iee?iaoii aea?aiaaiieie ee?uaie ?iaeo Dermatophagoides.

4. ?ic?iaeoe iioeiaeuei? ?aaeeie aeei?enoaiiy e?eoaaeueiiai
i?e?iee?iaoo i?ei?uaiue a eiiieaeni?e a?aeiiaethaai?e oa?ai??
ae?oae, oai?eo ia a?iio?aeueio anoio, a oiiaao iaeao
aea?aia?aeae?eaiiy oa ioe?ieoe ?o aoaeoeai?noue ia i?aenoaa?
ee?i?/iiai, eaai?aoi?iiai aeine?aeaeaiue oa a?aeaeaeaieo ?acoeueoao?a.

 Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a

Aia?oa aoa ?ic?iaeaiee oa aeei?enoaiee iiaee iaoiae eiiieaenii?
a?aeiiaethaaii? oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c
canoinoaaiiyi iiaeeo?eiaaii? iaeaoe e?ea?i? c o?eniaaieie ia?aiao?aie
e?eoaaeueiiai i?e?iee?iaoo oa /enoioe iia?o?y. Aecia/aii iioeiaeueiee
?aaeei – uiaeaiia 10 aiaeeiia ia?aaoaaiiy o aoiinoa??
ae??aiiaeenia?niiai nooiai ?ii?ciaaiiai aa?icieth iao??th oei?eaeo c
iino?eiith o?eueo?aoe??th iia?o?y i?ioyaii 15 ae?a. Aeiaaaeaii, ui
aeei?enoaiiy oeueiai iaoiaeo o a?aeiiaethaaeuei?e oa?ai?? oai?eo ia
a?iio?aeueio anoio ae?oae, i?aeaeuo? ?? aoaeoeai?noue ca oiia
oaeaeei? ii?iae?caoe?? a?iio?aeueii? i?io?aeiino?, ii?iae?caoe??
i?e?ia?ioeaiico, ui iiaeiaaeo? ?ai?n?th oai?iae. Anoaiiaeaii, ui
e?eoaaeueiee i?e?iee?iao ni?ey? ?icaeoeo oiea?aioiino? aei o?ce/iiai
iaaaioaaeaiiy o oai?eo ia a?iio?aeueio anoio. Aecia/aii oaeo
cieaeaiiy ??aiy caa?oaeiaiiy na?aaeiaeua ee?uaie iiaooiaiai ieeo a
oiiaao e?eoaaeueiiai i?e?iee?iaoo iaeao.

 I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

?ic?iaeaii oa aei?iaoaaii iiaee can?a eiiieaenii? a?aeiiaethaaii?
oa?ai?? ae?oae, oai?eo ia a?iio?aeueio anoio, c canoinoaaiiyi
e?eoaaeueiiai i?e?iee?iaoo iaeao. Eiai aeei?enoaiiy ni?ey?
ciaioaiith o?eaaeino? ia??iaeo caaino?aiiy oai?iae, oa?i?io
ia?aaoaaiiy o noaoe?iia??, iiia?aaeaea? ?aaeoe?? a?iioieiino?eeoe?? i?e
o?ce/iiio iaaaioaaeaii? ca ?aooiie ciaioaiiy nooiaith
a?ia??aaeoeaiino? a?iio?a, ni?ey? a?aeiiaeaiith i?e?ia?ioeaiico aa?oi?o
aeeoaeueieo oeyo?a, ?noioii iie?ioo? a?aeaeaeai? ?acoeueoaoe
e?eoaaiiy ( ciaioaiiy e?eueeino? aaaeeeo iaiaae?a yaeooe, ciaioaiiy
iio?aae a e?eao, i?aeaeuaiith o?eaaeino? ?ai?n??). A iaeaoao c
e?eoaaeueiei i?e?iee?iaoii iie?ioo?oueny a?a??i?/iee noai ca oiia
ciaioaiiy caa?oaeiaiiy aea?aaiieie i?iaeoeoaie aeeoo?ae?yeueiino?
ee?u?a iiaooiaiai ieeo. Ia i?aenoaa? aeine?aeaeaiue i?eiai? oaeaeeino?
aeaeeoo (IOA) 383 caei?iaeo ae?oae aeaaaeai? ?aa?an?? ii??aiyiiy
i?i?iaeueieo cia/aiue IOA ( a caeaaeiino? a?ae noao? oa c?inoo ae?oae).

Io?eiai? ?acoeueoaoe aoee aeiaaaeai? oa iaaiai?ai? ia
Caii??cuee?e iaeani?e iaoeiai-i?aeoe/i?e eiioa?aioe?? o?c?ioa?aiaao?a,
aea aoei noaaeaii aeei?enoaiiy e?eoaaeueiiai i?e?iee?iaoo a oa?ai??
oai?eo ia a?iio?aeueio anoio.

?acoeueoaoe aeine?aeaeaiue oi?iaaaeaeai? a i?aeoeeo ?iaioe iaeaniiai
aea?aieia?/iiai a?aeae?eaiiy oa iie?ee?i?/iiai a?aeae?eaiiy aeeoy/i?
ee?i?/ii? e?ea?i? N 5 i. Caii??aeaey, aea?aioeaio?o i. Caii??aeaey,
iaeanii? e?ea?i? i. Aei?i?iiao?ianueea, niae?inaiaoi??th “Aeiiaan”
i.A?oai?anuee Aeiiaoeueei? iaeano?.

 Iniaenoee aianie caeiaoaa/a.

Aeena?oaioii naiino?eii ianoaaeaii 225 ae?oae, oai?eo ia
a?iio?aeueio anoio, ye? ciaoiaeeeenue a aea?aieia?/iiio a?aeae?eaii?.
?ic?iaeaii iaeiioeiaeuei?oee ?aaeei a?aeiiaethaaii? oa?ai?? a oiiaao
e?eoaaeueiiai i?e?iee?iaoo iaeao ( ae??aiiaeenia?niee nooee
?ii?ciaaiee aa?icieue iao??th oei?eaeo iecueei? eiioeaio?aoe?? oa
iino?eii? o?eueo?aoe?? iia?o?y). Anoaiiaeai? ii?iaeuei? iieacieee
i?eiai? oaeaeeino? aeaeeoo (IOA) o ae?oae, iaoeaioe?a i. Caii??aeaey
(383) oa ??aiyiiy aeey i?ae?aooieo IOA. Anoaiiaeaii oaeo cia/iiai
cieaeaiiy ??aiy caa?oaeiaiiy na?aaeiaeua iaeao c e?eoaaeueiei
i?e?iee?iaoii ee?uaie iiaooiaiai ieeo ( iaoiaeii o?iiaoia?ao?/iiai
aeine?aeaeaiiy e?eueeino? aoai?io). I?iaaaeaia ioe?iea aoaeoeaiino?
e?eoaaeueiiai i?e?iee?iaoo iaeao ca ie?aieie ?acoeueoaoe ianoaaeaiiy o
38 oai?eo ia a?iio?aeueio anoio ae?oae.

 Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??

Aeiiia?aeue iaoa??ae?a ?iaioe aoea c?iaeaia ia can?aeaiiyo
oiaa?enoaa aeeoy/eo e?ea??a i. Caii??aeaey oa iaeano? o 1994-1997 ??.,
Iaoe?iiaeueiiio Eiia?an? ii oai?iaai i?aai?a aeeoaiiy o i. Iineaa o
1994?., ia iaeani?e iaoeiai-i?aeoe/i?e eiioa?aioe?? o?c?ioa?aiaao?a
(i. Caii??aeaey, 1995?.), oa?eoee aei iaoiaee/iiai iin?aieea “Ioe?iea
o?ce/iiai ?icaeoeo oa noaoaaiai aeic??aaiiy ae?oae oa i?aee?oe?a
(i.Aei?i?iiao?ianuee,1997).

Ai?iaaoe?y aeena?oaoe?? a?aeaoeanue ia ni?eueiiio can?aeaii? eaoaae?
oaeoeueoaonueei? oa aini?oaeueii? iaae?ao??? Caii??cueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.

 Ioae?eaoe??

?acoeueoaoe aeena?oaoe?eii? ?iaioe aeeeaaeaii o ioae?eaoe?yo, na?aae
yeeo 3 aeo?iaeueieo noaoo? ( naiino?ei?), 3 – c ni?aaaoi?aie, 7 oac
aeiiia?aeae, 1 iaoiaee/i? ?aeiiaiaeaoe??.

 No?oeoo?a oa ianya aeena?oaoe??

Aeena?oaoe?th aeeeaaeaii ia 133 a?eooao iaoeiiieno. Aiia i?noeoue
anooi, iaeyae e?oa?aoo?e, ia’?i ? iaoiaee aeine?aeaeaiiy, ?acoeueoaoe
aeanieo niinoa?aaeaiue, caeeth/aiiy,

aeniiaee, i?aeoe/i? ?aeiiaiaeaoe??. Ia?ae?e aeei?enoaii? e?oa?aoo?e
i?noeoue 245 aeaea?ae, 70 c yeeo -eaoeiith. Aeena?oaoe?th
i?i?ethno?iaaii 7 iaethieaie, 26 oaaeeoeyie.

 INIIAIEE CI?NO ?IAIOE.

Ia’?i, iaoiaee oa iaoiaeeee aeine?aeaeaiiy. Aeey ae??oaiiy iinoaaeaieo
caaea/ o iaeaoao aea?aieia?/iiai a?aeae?eaiiy iiaeaethaaee
e?eoaaeueiee i?e?iee?iao ca aeiiiiiaith i?eeaaeo – aaia?aoi?o
ae??aiiaeenia?niiai nooiai aa?icieth iao??th oei?eaeo, aeio?eioaaee
oiiae aeey cieaeaiiy ai?noo aa?iaea?aai?a oeyoii ?aaeeiieo caoiae?a oa
o?eueo?aoe?? iia?o?y. Aeei?enoiaoaaeenue ianooii? ia?aiao?e
i?e?iee?iaoo: eiioeaio?aoe?y aa?icieth iao??th oei?eaeo 0,34 ia/ i
eoa., ?ici?? ia?aaaaeath/eo /anoie 0,3 iei, ai?no iaaaoeaii
ca?yaeaeaieo ?ii?a 10260 iae/ ni eoa..

I?ae iaoei iaaeyaeii ciaoiaeeeinue 225 oai?eo ia a?iio?aeueio anoio
(AA) ae?oae a?eii a?ae 4 aei 15 ?ie?a, ye? iaoeaee a i. Caii??aeae? oa
iaeano?. O 188 oai?eo (83,5%) anoaiiaeaii ae?aaiic aoii?/ii? oi?ie AA,
o 37 (16,5 %) – ae?aaiic ci?oaii? oi?ie AA. Aeey i?iaaaeaiiy
ii??aiyeueieo aeine?aeaeaiue ianoaaeaii 400 caei?iaeo ae?oae. I?e
ianoaaeaii? oai?iai aea/aee i?eeiyo? ee?i?/i? oa eaai?aoi?i? iieacieee.
On?i ae?oyi i?ae /an ?ai?n?? i?iaaaeai? aea?aieia?/ia ianoaaeaiiy.
Eiio?ieue ca noaiii ooieoe?? ciai?oiueiai aeeoaiiy (OCAe) cae?enithaaany
ca aeiiiiiaith ni??iiao?o o??ie “Aoii”(Aieaa??y), ii?oaoeaiiai
i?eeaaeo “Peak-Flaw-Meter” o??ie “Airmed” (Aaeeeia?eoai?y) aeey
aecia/aiiy iaeiiai ?c aeeiai?/ieo iieaciee?a OCAe – i?eiai? oaeaeeino?
aeaeeoo (IOA), yeo aeine?aeaeoaaee aeae?eueea ?ac?a ia aeiao i?ioyaii
onueiai /ano niinoa?aaeaiiy. O /anoeie ae?oae i?iaaee oano c
o?ce/iei iaaaioaaeaiiyi o e?eoaaeueiiio i?e?iee?iao? oa cae/aeiiio
na?aaeiaeu?. I?iaa i?iaiaeeeanue ia aaeia?aiiao?? i?ae /an aeeiiaiiy
aeeoeiith o?ce/ii? ?iaioe iiooaei?noth 1 ao/ea iane i?ioyaii 5 oaeeei ca
aeinyaiaiiyi ioeueno 150-170 oaea??a ca oaeeeio a eaai?aoi??? ?c
oaiia?aoo?ith iia?o?y 20-25 N, a?aeiiniith aieia?noth 50%. Oano
aaaaeaee iiceoeaiei, yeui a?aenioie iaae?iiy IOA neeaaeaa a?eueo
10 o ii??aiyii? c iieacieeaie ia?aae iaaaioaaeaiiyi (K.M.Tan,
R.T.Wall, 1985).

Aeey ii??aiyiiy nooiaith ii?ooaiiy a?iio?aeueii? i?io?aeiino? ca
iieacieeaie IOA iaie aoee aecia/ai? ooi/iai? iieacieee IOA o 383
caei?iaeo ae?oae – iaoeaioe?a i. Caii??aeaey. I?i?iaeueia ( iaaeoth/a
c? noaiii aaia?ae?ciaaii? a?iio?aeueii? iano?oeoe??) IOA iiaea aooe
aecia/aia ca ii??aiyiiyie : aeey oeii/ee?a y = 3,94x – 268, aeey
ae?a/aoie – y = 3,88x – 275, aea y -cia/aiiy IOA e/oa., x – c??no
aeeoeie o ni.

I?e?ia?ioeaiic neeciaeo aa?oi?o aeeoaeueieo oeyo?a aecia/aee
e?euee?niei iaoiaeii, ii??aithth/e ii/aoeia? aeai? c iieacieeaie,
io?eiaieie iaie o caei?iaeo ae?oae, ia ii/aoeo oa i?e e?ioe?
eiiieaenii? a?aeiiaethth/i? oa?ai?? ( E.A.Eieioeeiaa,1986). Aecia/aee
?ioiieia?/i? iieacieee ia?oiai ??aiy ca ?.A.Iao?iaei
(1982)-noaiiioeyoe?? e?ioioeeo?a o oanoao ?acaoeiooai?thaaiiy (?OE)
ca M.Jondel ?c ni?a?ia?o. (1974), oaio?e?icaeaaei? O-e?ioioeeoe
iaoiaeii A.E.*a?iooaiei ?c ni?aaao.(1983). Aoii?aeueio eaieo ?ioi?oaoo
ioe?ithaaee ca iniiaieie eeanaie ?ioiiaeiaoe?i?a A,M,G ne?iaaoee e?ia?
ca Q.Mancini (1965).

O eiiieaeniiio e?eoaaii? ae?oae, oai?eo ia AA, canoiniaoaaee aeaa
?aaeeie ia?aaoaaiiy a oiiaao e?eoaaeueiiai i?e?iee?iaoo iaeao: ia?oee
oa?aiaaoe/iee ?aaeei neeaaeaany c ia?aaoaaiiy oai?eo o aoiinoa??
aa?icieth 1 aiaeeio, ae?oaee – i?noea o nia? uiaeaiia ia?aaoaaiiy o
iaeaoao ai?iaeiaae 10 aiaeei i?ioyaii 15 ae?a.

?c o?aooaaiiyi i?eioeei?a nenoaiiino? i?aai?caoe??
iaaeeei-a?ieia?/ieo aeine?aeaeaiue (E.Aa?oieaio?,1969), aoee ?icoe?ai?
iaae? ee?i?/iiai aeine?aeaeaiiy. Aea/aee nenoaio “oai?ee ia
AA-ee?u? aeiiaoiueiai ieeo” a oiiaao e?eoaaeueiiai i?e?iee?iaoo.
Aecia/aee o ieeo iaeao ai?no aoai?io-aeieia?/iiai ia?ea?o oaeaeueiiai
caa?oaeiaiiy na?aaeiaeua ee?uaie, iaoiaeii aenieiaoaeoeaii? ??aeeiii?
o?iiaoia?ao?? ia o?iiaoia?ao? “I?e?o?ii” (I.A.?aaiueei,1991),
aeei?enoiaoth/e ye noaiaea?o aoai?i o??ie “Ia?e” (I?ia//eia) c
a?aeiieie niaeo?aeueieie oa?aeoa?enoeeaie.

I?aai?caoe?y aeine?aeaeaiue iieyaaea o ii??aiyeueiiio aea/aii?
?aiaeii?ciaaieo a?oi oai?eo, ye? io?eioaaee eiiieaenio a?aeiiaethth/o
oa?ai?th o iaeaoao c e?eoaaeueiei i?e?iee?iaoii, oa oeo, ui
ciaoiaeeeenue o iaeaoao c “ieaoeaai-i?e?iee?iaoii”. Canoiniaoaaee
iaeiiiiiaioi? ii??aiyeuei? niinoa?aaeaiiy c ?enaie eiia?othaeiiai
iaoiaeo niinoa?aaeaiiy ca oai?eie. Ioe?ieo aeaieo
ee?i?ei-eaai?aoi?ieo, aeieiai-a?a??i?/ieo aeine?aeaeaiue i?iaiaeeee ca
iaoiaeaie aa??aoe?eii? noaoenoeee (A.O.Eae?i,1990).

 ?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy.

Aeey aea/aiiy aoaeoeaiino? e?eoaaeueiiai i?e?iee?iaoo iaeao oai?eo aoei
?icae?eaii ia aea? a?oie. 106 ae?oae ciaoiaeeeenue a oiiaao
e?eoaaeueiiai i?e?iee?iaoo iaeao aea?aia?aeae?eaiiy (aeine?aeia a?oia),
78 ae?oae neeaaeaee eiio?ieueio a?oio, a yeee canoiniaoaaee
“ieaoeaai-i?e?iee?iao”. A?oie ae?oae aoee ?aoaeueii ?aiaeii?ciaai?.
A?eueo?noue ae?oae – 86% o aeine?aei?e a?oi? oa 87% a eiio?ieuei?e
a?oi?, no?aaeaeaee ia aoii?/io AA. Ia?aaaaeaee ae?oe c na?aaeiueiaaaeeei
ia?aa?aii caoai?thaaiiy: 70% – o aeine?aei?e a?oi? oa 67% – o a?oi?
eiio?ieth. O ia?aaaaeii? a?eueoino? ae?oae o?eaae?noue oai?iae
neeaaeaea a?eueoa ?ieo ( 79% oa 76%, a?aeiia?aeii). I?e
i?iaaaeaii? aea?aioanooaaiiy aeyaeaii, ui o ae?oae a iaio a?oiao aoea
aeniea /anoioa nainea?e?caoe?? aei aea?aai?a ee?u?a aeiiaoiueiai ieeo:
o ae?oae aeine?aeii? a?oie /anoioa nainea?e?caoe?? aei aea?aaio
ee?u?a Dermatophagoides pteronissinus -79,7% , o ae?oae eiio?ieueii?
a?oie – 85,4%. Ii?ooaiiy OCAe ca iano?oeoeaiei oeiii aoee ae?aaiinoiaai?
o an?o ae?oae iaio a?oi. IOA o ae?oae aeine?aeii? a?oie ia ii/aoeo
e?eoaaiiy neeaea 73+3%, o ae?oae eiio?ieueii? a?oie – 74+4% a?ae
iaeaaeieo cia/aiue.

O i?ioean? niinoa?aaeaiiy ca 28 oai?eie i?e canoinoaaii? ia?oiai
oa?aiaaoe/iiai ?aaeeio e?eoaaeueiiai iee?ieeeiaoo iia??oaiiy
naiiii/oooy ia aoei ca?a?no?iaaii o aeiaeiiio aeiaaeeo i? i?ioyaii 1
aiaeeie, i? o ianooii? aeae?eueea aiaeei. sse iieacaa ii??aiyeueiee
aiae?c iieaciee?a IOA, o ae?oae a aeine?aei?e a?oi? i?e??no IOA ia 15 %
oa a?eueoa o ii??aiyii? c ii/aoeiaeie cia/aiiyie a?aecia/aii o 61%
oai?eo, a oie /an , ye o eiio?ieuei?e a?oi? cia/io aaao iaee noii?ai?
oa iaaaoeai? ?acoeueoaoe – 54% (p

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