14

I?i?noa?noai ioi?iie caei?iay Oe?a?ie

Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao

Iicaiaee TH??e Noaiaiiae/

OAeE: 618.145-007.415-08:616.381-172.1

EAIA?INEII?*IA OA EIIA?IIAAIA C AAII?NOAIE AIIAAeIO?II?I-?EE?CEIA
AI?IIIO E?EOAAIIss OAI?EO C AIAeIIAO??ICII ???-IV NOAAe??

14.01.01 — aeooa?noai oa a?iaeieia?y

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Iaeana – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Iaeanueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? IIC
Oe?a?ie

Iaoeiaee ea??aiee:

/eai-ei?aniiiaeaio AII Oe?a?ie, aeieoi? iaaee/ieo iaoe,

i?ioani? Caii?iaeai Aaea??e Ieeieaeiae/,

Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e aeooa?noaa oa a?iaeieia??

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani?

?aaithoa E?ae?y ?aai?aia,

?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie,

caa?aeoaa/ a?aeae?eaiiy ?aaa?e?oaoe?? ?ai?iaeoeoeaii? ooieoe?? ae?iie,
i. Ee?a

aeieoi? iaaee/ieo iaoe, i?ioani?,

Cae?inueeee Ieaenaiae? Ieaen?eiae/,

Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoaa/ eaoaae?e ia?eiaoaeueii? iaaeeoeeie,

aeeoy/i? oa i?aee?oeiai? a?iaeieia??

I?ia?aeia onoaiiaa:

Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i.aeaae. I.I. Aiaiiieueoey,

eaoaae?a aeooa?noaa oa a?iaeieia?? ? 1 IIC Oe?a?ie, i. Ee?a

Caoeno a?aeaoaeaoueny 30.eenoiiaaea 1999 ?ieo i 15:00 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 41.600.01 Iaeanueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (270026, i. Iaeana, i?ia.
Aae?oianueeee,2)

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Iaeanueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (270026, i. Iaeana, i?ia.
Aae?oianueeee,3)

Aaoi?aoa?ao ?ic?neaiee 28. AEiaoiy 1999?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani? Aiaeeaanueeee E.N.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Aeooaeuei?noue i?iaeaie aaeineiiaeaiiy e?eoaaiiy
aiaeiiao??ico ia i?ioyc? inoaiiueiai aeanyoe??//y cia/ii c?inea. A ia?oo
/a?ao oea oi?ea?oueny oyaeeeo eiai oi?i, ye? ? /anoith i?e/eiith
oaciaiai aieth, ii?ooaiiy ?ai?iaeoeoeaii? ooieoe?? ae?iee, cieaeaiiy ??
i?aoeacaeaoiino? (A.?.A?euaiei, 1996; E.A. Aaeaiyi, A.I. Eoeaeia,
1998).

Iniaeeai? aino?ioe i?iaeaia aacie?aeiino? iaaoaa? o e?a?iao ?c
iaaaoeaieie aeaiia?ao?/ieie iieacieeaie, ui iio?aao? ?ic?iaeaiiy oa
ai?iaaaeaeaiiy iiaeo ae?aaiinoe/ii-e?eoaaeueieo i?aeoiae?a
(I.I.Cae?inueeee, 1992; E.?.?aaithoa, 1995; ?.A. Aiaaoe?ueiaa, 1998;
I.A.Aieaea, 1998; A.I.Aaioee?anueeee, 1998).

Iacaaaeath/e ia aaeeeo e?euee?noue aeine?aeaeaiue, i?enay/aieo
??ciiiai?oiei aniaeoai aiaeiiao??ico, caeeoathoueny iac’yniaaieie
ao?iiaoiaaiac caoai?thaaiiy, iniaeeaino? ee?i?/ii? ea?oeie a caeaaeiino?
a?ae eieae?caoe?? oa noaae?? i?ioeano oa i?e/eie, eio?? aaciina?aaeiuei
i?eaiaeyoue aei aacie?aeiino? (A.I.No?eaeaeia, A.E. Aeaauaeia, 1995;
A.A. Eioaiaae/, 1998).

*eneaii? ioae?eaoe?? i?enay/ai? ae?aaiinoeoe? aiaeiiao??ico, i?ioa ia
ccyniaaia ?ioi?iaoeai?noue eiaeiiai c iaoiae?a (A.E. AEaeaciia, 1993;
A.?.A?euaiei, 1996; ?.C. Aeaae/oe, 1999).

Iaiaeiicia/i? iiaeyaee ia aea?? iaoiaeo e?eoaaiiy aiaeiiao??ico. Oea
coiiaeaii, c iaeiiai aieo, iiyaith iiaiai iieie?iiy ai?iiiaeueieo
cania?a – aaii?no?a aiiaaeio?ii?i-?ee?ceia ai?iiio (Ai?A), c ?ioiai –
oe?ieei ai?iaaaeaeaiiyi a i?aeoeeo eaia?ineii?/ii? iia?aoeaii? oaoi?ee.

Iniiao e?eoaaiiy oyaeeiai aiaeiiao??ico ia nueiaiaei? neeaaeathoue
o??o?a?/ia ao?o/aiiy ? iaaeeeaiaioicia oa?ai?y (A.I. Aaioee?anueeee,
1994; A.I. Caii?iaeai, 1998; ?. Donnez et al., 1994; C. Nezhat et al.,
1995; P.R. Koninckx, 1998). Ca inoaii? aeanyoe??//y ye iaeei, oae ?
ae?oaee i?aeoiaee caciaee cia/iiai ?icaeoeo.

Ia nueiaiaei? ia ?nio? ?aeeiiai iiaeyaeo noiniaii ie?aiiai aai
eiia?iiaaiiai aeei?enoaiiy oeeo iaoiae?a e?eoaaiiy oa iine?aeiaiino? ?o
canoinoaaiiy (D.B. Redwine, 1993; I. Donnez et al., 1994; E.J. Thomas,
1995; A.I.Aeoeyaaa, 1997; E.A. Aaeaiyi, 1997). I?e aacie?aeiino?,
iiacycai?e c aiaeiiao??icii, iaai? iaae?? iieeaaeathoueny ia
eaia?ineii?/ia e?eoaaiiy c canoinoaaiiyi eaca??a (A.I. Caii?iaeai oa
ni?aaao., 1998). I?ioa iiaeeeaino? ie?aiiai canoinoaaiiy
eaia?ineii?/iiai e?eoaaiiy o oai?eo c aiaeiiao??icii ???-?V noaae??
caeeoathoueny iaaeinoaoiuei aea/aieie. Iio?aao? iiaeaeueoeo
aeine?aeaeaiue ee?i?/ia aoaeoeai?noue eiia?iiaaiiai e?eoaaiiy c
i?neyiia?aoe?eiei aeei?enoaiiyi aaii?no?a Ai?A oa eiai aieea ia
iieacieee ?ioiiiai oa aiaeie?eiiiai noaoono. Nooo?aeie i?ioe??//yie
a?aecia/athoueny ? a?aeaeaeai? ?acoeueoaoe i?ney eaia?ineii?/iiai ?
eiia?iiaaiiai c aaii?noaie aiiaaeio?ii?i-?ee?ceia ai?iiio e?eoaaiiy.

Cacycie ?iaioe c iaoeiaeie ieaiaie, i?ia?aiaie, oaiaie. Aeena?oaoe?y
iiacycaia c ieaiiaith iaoeiai-aeine?aeiith oaiith IAeIO “I?iaeaie
iaoa?einoaa, aeeoeinoaa oa n?ic? a no/anieo nioe?aeueii-aeiiii?/ieo
oiiaao Oe?a?ie” (? aea?ae?a?no?aoe?? 0196U018907).

Iaoa ? caaea/? aeine?aeaeaiiy. Iaoith aeine?aeaeaiiy aoei i?aeaeuaiiy
aoaeoeaiino? e?eoaaiiy oai?eo c aiaeiiao??icii ???-IV noaae?? oeyoii
aeeoa?aioe?eiaaiiai canoinoaaiiy eaia?ineii?/iiai o??o?a?/iiai e?eoaaiiy
oa eiai eiia?iaoe?? c aaii?noaie aiiaaeio?ii?i-?ee?ceia ai?iiio .

Aeey aeinyaiaiiy iaoe iinoaaeai? ianooii? iniiai? caaea/?:

1. Ioe?ieoe iiaeeeaino? eaia?ineii?? o aea/aii? eieae?caoe?? oa nooiaiy
iioe?aiiy aiaeiiao??i?aeieo aaoa?ioii?e o oai?eo aiaeiiao??icii ???-IV
noaae??.

2. Aea/eoe iniaeeaino? noaio aiaeie?eiii? oa ?ioiii? nenoai o oai?eo c
eaia?ineii?/ii aa??o?eiaaiei aiaeiiao??icii ???-IV noaae??.

3. ?ic?iaeoe iaoiaeeeo aeeoa?aioe?eiaaiiai i?aeoiaeo aei canoinoaaiiy
eaia?ineii?/iiai ? eiia?iiaaiiai iaoiae?a e?eoaaiiy o oai?eo
aiaeiiao??icii ???-IV noaae??.

4. I?iaiae?coaaoe ee?i?/io aoaeoeai?noue oa ci?ie iieaciee?a
aiaeie?eiii? oa ?ioiii? nenoai a ?acoeueoao? canoinoaaiiy
eaia?ineii?/iiai ? eiia?iiaaiiai e?eoaaiiy o oai?eo aiaeiiao??icii
???-IV noaae??.

5. ?ic?iaeoe oa ai?iaaaeeoe aeai?eoi aaaeaiiy oai?eo aiaeiiao??icii
???-IV noaae?? c canoinoaaiiyi eaia?ineii?/iiai ? eiia?iiaaiiai iaoiae?a
e?eoaaiiy caeaaeii a?ae a?eo oai?eo, ?ai?iaeoeoeaieo iai???a,
iniaeeainoae eieae?caoe?? ina?aaee?a aiaeiiao??ico oa noiooiuei?
iaoieia??.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa i?iaaaeai? eiiieaeni?
aeine?aeaeaiiy iniaeeainoae noaio aiaeie?eiii? oa ?ioiii? nenoai o
oai?eo c eaia?ineii?/ii aa?eo?eiaaiei aiaeiiao??icii ???-IV noaae?? oa
aea/ai? ?o ci?ie a ?acoeueoao? iia?aoeaiiai eaia?ineii?/iiai ?
eiia?iiaaiiai iaoiae?a e?eoaaiiy. ?ic?iaeai? iieacaiiy aei canoinoaaiiy
iia?aoeaiiai eaia?ineii?/iiai oa eiia?iiaaiiai e?eoaaiiy c aeei?enoaiiyi
aaii?no?a aiiaaeio?ii?i-?ee?ceia ai?iiio (cieaaeaeno) o oai?eo c
aiaeiiao??icii ???-IV noaae??. Aia?oa ai?iaaaeaeaii aeeoa?aioe?eiaaiee
i?aeo?ae aei canoinoaaiiy iia?aoeaiiai eaia?ineii?/iiai ? eiia?iiaaiiai
iaoiae?a e?eoaaiiy o oai?eo c aiaeiiao??icii ???-IV noaae?? a
caeaaeiino? a?ae a?eo iaoe??ioee, ?ai?iaeoeoeaieo iai???a, oa?aeoa?o
noiooiuei? a?iaeieia?/ii? iaoieia??, iniaeeainoae eieae?caoe??
ina?aaee?a aiaeiiao??ico.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. I?aeoe/ia cia/ei?noue
?iaioe iieyaa? o i?aeaeuaii? aoaeoeaiino? e?eoaaeueieo caoiae?a i?e
aiaeiiao??ic? ???-IV noaae??, ?ic?iaoe? aeeoa?aioe?eiaaiiai i?aeoiaeo
aei aeai?o iaoiaeo e?eoaaiiy a caeaaeiino? a?ae noaio ?ai?iaeoeoeaii?
ooieoe??, a?eo, iioe?aiiy aiaeiiao??i?aeieo o?aaeaiue.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii iniaenoi i?iaaaeaiee aanue ianya
ee?i?/ieo aeine?aeaeaiue ? e?eoaaeueieo caoiae?a o 110 ae?iie c
aiaeiiao??icii ???-?V noaae??, yeee aeeth/aa ioe?ieo ee?i?/iiai noaio
oai?eo oa aeeiiaiiy aiaeineii?/ieo ao?o/aiue, i?ecia/aiiy a?aeiia?aeiiai
?iaeea?aeoae?ciaaiiai e?eoaaiiy, ioe?ieo eiai aoaeoeaiino?. Iniaenoi
noai?aiee aeai?eoi aaaeaiiy oai?eo c aiaeiiao??icii ???-?V noaae?? ?c
canoinoaaiiyi iia?aoeaiiai eaia?ineii?/iiai oa eiia?iiaaiiai e?eoaaiiy.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aeiiia?aeaeenue ia ?? Iaoe?iiaeueiiio eiia?an? iieiaeeo a/aieo-iaaeee?a
Oe?a?ie (1994), ?? ?in?enuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? “I?iaeaiu
yiaeineiiee a aeiaeieiaee” (1995), I?aeia?iaeiiio neiiic?oi?
“Aanieiaeea, A?O-2000” (1999), iaoeiai-i?aeoe/ieo eiioa?aioe?yo
Iaeanueeiai iaeaniiai iaoeiaiai oiaa?enoaa aeooa??a oa a?iaeieia?a
(1996-1999).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 7 iaoeiaeo i?aoeue.

No?oeoo?a oa ianya aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 142
noi??ieao iaoeiiieniiai oaenoo, ?ethno?iaaia 19 oaaeeoeyie, 6 ?enoieaie,
neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, iieno iaoa??ae?a ? iaoiae?a
aeine?aeaeaiiy, 3 ?icae?e?a aeanieo aeine?aeaeaiue, aiae?co ?
ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiue, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e, nieneo aeei?enoaii? e?oa?aoo?e c 82 ?ia?o a?o/eciyieo ?
112 ca?oa?aeieo aaoi??a.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy. I?ae iaoei niinoa?aaeaiiyi
ia?aaoaaee 110 ae?iie ?c ciai?oi?i aiaeiiao??icii ???-?V noaae?? ca?aeii
ia?aaeyiooi? eeaneo?eaoe?? Aia?eeainueeiai Oiaa?enoaa Oa?oeeueiino?
(1985). Eiio?ieueio a?oio neeaee 20 caei?iaeo iaaaa?oieo ae?iie. Aea/aee
oa?aeoa? nea?a, aiaiiac aeeooy oa iniiaiiai caoai?thaaiiy, noai
iaino?oaeueii?, noaoaai? ? ?ai?iaeoeoeaii? ooieoe??, i?iaiaeeee
caaaeueiiee?i?/ia ? niaoe?aeueia ianoaaeaiiy.

Ioe?ieo ooieoe?iiaeueiiai noaio nenoaie a?iio?c-y?/ieee cae?enithaaee ca
?acoeueoaoaie aeine?aeaeaiiy a?ao?ea aacaeueii? oaiia?aoo?e oa ai?noo
aiiaaeio?iiieo ? noa?i?aeieo ai?iii?a. Aeine?aeaeaiiy ??aiy ai?iii?a o
ne?iaaooe? e?ia? i?iaiaeeee ?ioiioethi?anoeaioiei ? ?aae?i?ioiiei
iaoiaeii. Aea/aee ai?no o ne?iaaooe? e?ia? noa?i?aeieo ai?iii?a –
ano?aae?ieo (A2), i?iaanoa?iio (I), aiiaaeio?iiieo ai?iii?a –
oie?eoeinoeioethth/iai ai?iiio (ONA), ethoa?i?coth/iai ai?iiio (EA),
i?ieaeoeio (I?e).

Aeey oa?aeoa?enoeee noaio O- oa A-nenoai e?ioioeeo?a canoiniaoaaee
iaoiaee Felsburg et al. (1976); A.N. Iaaethe ? ni?aaao. (1982).
Aecia/aee caaaeueio e?euee?noue O-e?ioioeeo?a, O-ee?oeie, ye? iathoue
?aoeaioi?e aei Fn-o?aaiaioo ?ioiiaeiaoe?io I oa ?ioiiaeiaoe?io G,
caaaeueio e?euee?noue A-e?ioioeeo?a, A-ee?oeie, ye? iathoue ?aoeaioi?e
aei a?eo?ioeeo?a ieoae. Eiioeaio?aoe?th ?ioiiaeiaoe?i?a A, M, G o
ne?iaaooe? e?ia? aecia/aee ca G. Mancini et al., ai?no oee?eoethth/eo
?ioiieo eiiieaen?a – ca C. George et al.

O?ainaaaeii?iaeueia ? o?ainaaa?iaeueia oeueo?acaoeiaa neaioaaiiy
i?iaiaeeeinue ia aia?ao? Aloka SSD-680 (ssiii?y).

Ia caeeth/iiio aoai? ianoaaeaiiy o an?o iaoe??ioie aeeiioaaee
aiaeineii?/i? ao?o/aiiy. Aeey i?iaaaeaiiy aiaeineii?/ieo ao?o/aiue
canoiniaoaaee niaoe?aeuei? iaai?e iaeaaeiaiiy oa ?ino?oiaio?a
ae?iaieoeoaa “OLYMPUS” (ssiii?y), “KARL STORZ” oa “MARTIN” (I?ia//eia),
“CIRCON”(NOA). Aeey aeeiiaiiy iia?aoeaieo aiaeineii?/ieo ao?o/aiue
aeei?enoiaoaaee aia?ao aeey aeniei/anoioii? aeaeo?io??o?a?? IA-400
“MARTIN” (I?ia//eia), aaia?aoi? aethii-?o??e-a?aiaoiaiai eaca?a Medilas
4060 N MBB (I?ia//eia).

Ciaaiethaaiiy i?e iia?aoe?? cae?enithaaee oeyoii iae?ieaioaiaeueaac??
i?e ooo/i?e aaioeeyoe?? eaaaiue.

Eaia?ineii?th i?iaiaeeee ca oeiiaith iaoiaeeeith J. Phillips (1991), yea
aeeth/aea ianooii? aieiai? aoaie: 1) ia?iaea iia?aoe?eiiai iiey, 2)
iaeeaaeaiiy iaoeiai? eaithe?, 3) iaeeaaeaiiy iiaaiiia?eoiiaoio, 4)
aaaaeaiiy ia?oiai o?iaea?a oa ii/aoie iaeyaeiaiai (ae?aaiinoe/iiai)
aoaio eaia?ineii??, 5) i?iaaaeaiiy aeiaeaoeiaeo i?ieie?a aeey
iai?ioeyoi??a, 6) iiaeeaeaia ?aa?c?y i?aai?a /a?aaii? ii?iaeieie, 7)
iia?aoeaiee aoai eaia?ineii??, 8) caeeth/iee aoai eaia?ineii?? –
aeaeaeaiiy iae?ii?aia?aoo, i?iieaaiiy /a?aaii? ii?iaeieie, eiio?ieue
aaiinoaco, aeaaaeaiiy aaco oa ?ino?oiaio?a, 9) iaeeaaeaiiy iiiaeeiieeo
oa?a aai neiaie ia i?noey i?ieie?a ia oe???.

Iiaaiiia?eoiiaoi iaeeaaeaee, ye i?aaeei, cae?eoei niiniaii ? a ie?aieo
aeiaaeeao – a?aee?eoei, ca iaoiaeeeith, iienaiith Hasson (1989). ??aaiue
?io?aaaaeii?iaeueiiai oeneo i?ae /an iia?aoe?e i?aeo?eioaaee aaoiiaoe/ii
a iaaeao 9-15 ii ?o.no. I?ieie aeey iioeee cae?enithaaee a i?noe?
aaaaeaiiy aieee Aa?aoa – iae/ano?oa ii ieaeiueiio e?ath ioieiaiai
e?eueoey. Aeiaeaoeia? i?ieiee aeeiioaaee a a?iiaano?aeuei?e oa
caeooaeii?e ae?eyieao e?euee?noth a?ae 1 aei 3, iae/ano?oa – 2.

O??o?a?/i? ao?o/aiiy aeeiioaaee ?c canoinoaaiiyi aeaeo?io??o?a?/ii? oa
eaca?ii? iia?aoeaii? oaoi?ee.

O 79 iaoe??ioie i?iaiaeeee a?noa?ineii?? ca iaoiaeeeith iienaiith J.
Phillips (1994).

Noaoenoe/io ia?iaeo iaea?aeaieo e?euee?nieo oa ye?nieo iciae i?iaiaeeee
ia ia?niiaeueiiio eiiiuethoa?? PC Pentium 300 MHz (16MbRAM/1,3 Gb HDD)
a aeaeo?iiieo oaaeeoeyo Microsoft Excel 97 aeey Windows-95.

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy. C 110 oai?eo ??? noaae?y
aiaeiiao??ico niinoa??aaeanue o 62(56,4%), ?V noaae?y – o 48(43,6%)
oai?eo. A?eueo?noue ianoaaeaieo iaie ae?iie (69,1%) aoea o a?oe? aei 35
?ie?a.

Oai?? c aiaeiiao??icii iaee iani?eyoeeaee i?aii?a?aeiee oii. O eiaeii?
o?aouei? ae?iee a aiaiiac? niinoa??aaeenue ?ioaeoe?ei? caoai?thaaiiy,
iae?iineo?/i? oa aaaaoinoaeeii? ii?ooaiiy. Caa?oa? ia naaa oaaao aaeeea
e?euee?noue caoai?thaaiue oeoieiai-eeoeiaiai o?aeoo (14,5%) oa
na/iaeae?eueii? nenoaie (8,2%), ui, iiaeeeai ao?iiaoiaaiaoe/ii iiacycaia
c iayai?noth aiaeiiao??i?aeieo o?aaeaiue. *anoi aiaeiiao??ic
noi?iaiaeaeothoue caiaeuei? i?ioeane i?eaeaoe?a iaoee (60,9%), i?iia
iaoee oa a?ia?ieanoe/i? i?ioeane aiaeiiao??th (28,2%).

Iaea?eueo /anoith (83,6%) nea?aith o an?o oai?eo aoa i?ia?anoth/ee
oaciaee aieueiaee neiae?ii c ???aae?aoe??th a i?yio eeoeo, i?oao, ieaei?
e?ioe?aee. E?euee?nia ioe?iea aieueiaiai neiae?iio o aeaeyae?
aieueiaiai ?iaeaeno (A?) neeaea 8,25+0,31 aae?a (ca Mac Loverty C.M.,
Shaw D.W.,1995). O 34,5% oai?eo aoee nea?ae ia aeenia?aoi?th. Iaeiei c
aaaeo/eo neiioii?a aiaeiiao??ico aoei ii?ooaiiy iaino?oaeueiiai oeeeeo,
aea a a?eueoino? aeiaaee?a ?o ia iiaeia aoei ?icoe?ieoe ye oyaee?. Eeoa
o 19,1% oai?eo ia aeyaeaii aeiaeieo ii?ooaiue iaino?oaeueiiai oeeeeo.
Aiae?c aaia?aoeaii? ooieoe?? iieacaa aenieo /anoioo ye ia?aeiiiai
(37,3%) oae ? aoi?eiiiai (18,2%) aacie?aeiino?.

Ca ?acoeueoaoaie i?iaaaeaieo ?ioiieia?/ieo aeine?aeaeaiue o ianoaaeaieo
oai?eo c aiaeiiao??icii aeyaeaii iciaee ?ioiiaeao?oeeoiiai noaio, ye?
i?iyaeyeeny i?eai?/aiiyi O-ee?oeiii? eaiee ?ioi?oaoo. Niinoa??aaeiny
cieaeaiiy (p<0,05) caaaeueii? e?eueeino? O-e?ioioeeo?a ye i?e ??? (45,1+1,4%), oae ? i?e ?V noaae?yo aiaeiiao??ico (38,5+1,7%), oa ?o oaeia?ii? noaiiioeyoe?? (Om)(???no. –20,7+0,9%, ?V no. - 20,0+0,8%) a ii??aiyii? c eiio?ieai (Ocaa. 58,1+3,1%, Om 37,5 +2,1% ). O ?acoeueoao? oeueiai ??aaiue ni?aa?aeiioaiiy Om/Og i?e ??? (1,14+ 0,06 ) oa ?V (1,16+0,05) noaae?? aiaeiiao??ico caciaaaa aeinoia??iiai cieaeaiiy ii??aiyii c iieacieeaie o i?aeoe/ii caei?iaeo ae?iie (1,9+0,1). Aeine?aeaeaiiyie aoii?aeueieo oaeoi??a ?ioi?oaoo aeyaeaii, ui i?e ciai?oiueiio aai?oaeueiiio aiaeiiao??ic? ???-?V noaae?? aeinoia??ii ca?eueoo?oueny o e?ia? ai?no iniiaiiai eeano ?ioiiaeiaoe?i?a – IgG (???no. - 22,2+1,9 a/e, ?Vno. - 24,1+1,9 a/e), a oaeiae a?aei?/aeiny ca?eueoaiiy ?ioiiaeiaoe?i?a eeano A (???no. - 2,2+0,099 a/e, ?Vno. - 2,4+0,1 a/e), a ii??aiyii? c eiio?ieai (Ig G – 12,2+0,9 a/e, Ig A – 1,2+0,12 a/e). I?e aeine?aeaeaii? ai?noo ?ioiiaeiaoe?i?a eeano I (???no. 1,1+0,06 a/e, ?Vno. 1,2+0,07a/e) nooo?ai? ??cieoe? i?ae a?oiaie oai?eo c aiaeiiao??icii ???-?V noaae?? oa caei?iaeie ae?ieaie (Ig M – 0,8+0,08 a/e) ia aeyaeaii. A?aeiiniee ai?no A-e?ioioeeo?a, ee?oei, ui aa?ooue o/anoue o i?iaeoeoe?? aioeo?e, o oai?eo c aiaeiiao??icii ??? (21+0,9%) oa ?V (24,2+1,1%) noaae?? nooo?ai aeuee, i?ae a eiio?ieuei?e a?oi? (16,0+2,2%). I?ioa aaniethoia e?euee?noue A-e?ioioeeo?a o an?o aeine?aeaeoaaieo a?oiao iaea oaiaeaioe?th aei ca?eueoaiiy ii??aiyii c eiio?ieai (0,37+0,078a/e). Oe? aeai? na?ae/aoue i?i oa, ui i?e ciai?oiueiio aiaeiiao??ic? ???-?V noaae?? a ee?oeii?e oa aoii?aeuei?e eaieao ?ioi?oaoo iathoue i?noea nooo?a? ii?ooaiiy, ye? iiaeia eeaneo?eoaaoe ye ?ioiiaeao?oeeoiee noai c O-e?ioioeeoa?iith noi?an??th ? aeoeaaoe??th A-ee?oeiii? nenoaie e?ioioeeo?a. O oai?eo c eaaeei ia?aa?aii aiaeiiao??ico ia aeyaeaii aeinoia??ieo a?aei?iiinoae o ??ai? iieaciee?a, ui oa?aeoa?ecothoue noai ee?oeiiiai ? aoii?aeueiiai ?ioi?oaoo, oi/a a?aei?/aia oaiaeaioe?y aei cieaeaiiy a?aeiinieo ? aaniethoieo cia/aiue Ocaa ? Om-e?ioioeeo?a. Iieacieee, ui oa?aeoa?ecothoue aoii?aeueio oa ee?oeiio eaiee ?ioi?oaoo i?e ?? noaae?? aiaeiiao??ico iaaeeaeothoueny aei oaeeo i?e ??? noaae?? caoai?thaaiiy. Oea iiaea na?ae/eoe, i?i oa, ui ?ioiieia?/i? ii?ooaiiy ? ia?aeiieie ? noai?ththoue oii aeey ?icaeoeo aiaeiiao??ico oa iiaeeaeththoueny i?e oyaeeeo eiai oi?iao. Aiie aeyaeythoueny iie?eeiiaeueiith aeoeaaoe??th A-ee?oeiii? nenoaie e?ioioeeo?a ia oe? O-e?ioioeeoa?ii? noi?an?? oa caeaaeaoue a?ae noaae?? caoai?thaaiiy. Iao? ?acoeueoaoe ni?aiaaeathoue c aeaieie A.A. Noa?oeaai?, 1987; E.ss. Noi?oi, 1996; A.?. ?uaiei, 1996. I?iaaaeai? iaie aeine?aeaeaiiy ai?noo aiiaaeio?iiieo ai?iii?a iieacaee aeinoia??ia ca?eueoaiiy eiioeaio?aoe?? EA oa ONA a ae?oa?e oac? iaino?oaeueiiai oeeeeo ye o oai?eo c ??? (EA - 10,68+0,21 IIe, p<0,05; ONA – 5,68+0,21 IIe, p<0,05) oae ? IV noaae??th aiaeiiao??ico (EA - 12,0+0,53 IIe, p<0,01; ONA – 5,76+0,29 IIe, p<0,05) a ii??aiyii? c eiio?ieai (EA - 8,32+0,75 IIe; ONA – 4,41+0,41 IIe). Oa?aeoa?iei aeey ianoaaeaieo oai?eo ? noaoenoe/ii aeinoia??ia i?aeaeuaiiy ??aiy i?ieaeoeio i?e ??? (19,5+1,0 ia/ie) oa IV noaae?? (18,1+0,9 ia/ie) a ii??aiyii? c iieacieeii eiio?ieueii? a?oie (14,7+1,0 ia/ie). Niinoa??aaeiny cieaeaiiy noa?i?aeiaaiii? ooieoe?? y?/iee?a, yea oa?aeoa?ecoaaeiny iaiiaiioe?ii?noth ethoa?iiai? oace oeeeeo ? i?iyaeyeiny aeinoia??iei cieaeaiiyi ??aiy i?iaanoa?iio (??? no. - 12,1+0,6 ia/ie, p<0,05; IV no. - 9,9+0,5 ia/ie, p<0,01) i?e aeaioaciiio iaino?oaeueiiio oeeee? o a?eueoino? oai?eo (78,2%) c aiaeiiao??icii ???-?V noaae?? a ii??aiyii? c eiio?ieai (15,4+1,1 ia/ie). O an?o oai?eo c ii?ooaiiyi ai?iiiaeueiiai aiiainoaco ae?aaiinoiaaii aiaeiiao??i?aei? e?noe y?/iee?a. O iaoe??ioie c ?ao?ioea?a?eaeueiei aiaeiiao??icii ai?no noa?i?aeieo oa aiiaaeio?iiieo ai?iii?a aeinoia??ii ia a?ae??ciyany a?ae eiio?ieth, ui oa?aeoa?ii ? aeey eaaeiai ia?aa?ao caoai?thaaiiy. Caaaeueiii?eeiyoa a?iaeieia?/ia aeine?aeaeaiiy aeaei ciiao ae?aaiinooaaoe aiaeiiao??ic o 70% iaoe??ioie, aea aoei iaaeinoaoi?i aeey eiai noaae?thaaiiy. I?e aoia?ao?/i?e ae?aaiinoeoe? iaea?eueo iioeiaeueiei ? aeei?enoaiiy o?ainaaa?iaeueiiai neaioaaiiy. Aiae?c iniiaieo oeueo?acaoeiaeo iciae aiaeiiao??ico aeicaieea iai cai?aeic?eoe aiaeiiao??i?aei? e?noe y?/iee?a aei i?iaaaeaiiy eaia?ineii?? o 91,8%, ?ao?ioea?a?eaeueiee aiaeiiao??ic – o 80% aeiaaee?a. Aea iacaaaeath/e ia aenieo ?ioi?iaoeai?noue o?ainaaa?iaeueii? aoia?ao??, oeae iaoiae ia aeaa iiaeeeaino? o iiaiiio iac?i? ioe?ieoe nooi?iue iioe?aiino? caoai?thaaiiy, o?aaeaiiy noi?aeieo i?aai?a, i/a?aaeie oa cacyceiaiai aia?aoo, ui a iiaeaeueoiio aoei anoaiiaeaii ca aeiiiiiaith eaia?ineii??. Oyaee?noue aiaeiiao??ico a aaeao ii oeae? AOO (1985) aoea ioe?iaia ianooiiei /eiii : 20-29 aae?a o 32 (29,1%), 30-39 aae?a – o 30 (27,3%), a?eueoa 40 aae?a – o 48 (43,6%) iaoe??ioie. Ca ?acoeueoaoaie eaia?ineii?/iiai ianoaaeaiiy 62(56,4%) oai?? a?aeianaii aei ??? noaae?? aiaeiiao??ico, 48(43,6%) –aei ?V noaae??. I?e eaia?ineii?/iiio ianoaaeaii? cae?nithaaeany ia o?eueee ae?aaiinoeea aiaeiiao??ico oa eiai noaae?thaaiiy, aea e ioe?ithaaeeny oiiia?aoi-aiaoii?/i? iniaeeaino? eieae?caoe?? ina?aaee?a aiaeiiao??ico. Iae/ano?oa cono??/aeeny aiaeiiao??i?aei? o?aaeaiiy y?/iee?a (81,8%), ??aeoa – ?ao?ioea?a?eaeueiee aiaeiiao??ic (10,9%). O 8 (7,3%) iaoe??ioie niinoa??aaeiny ii?aeiaiiy aiaeiiao??ico y?/iee?a oa ?ao?ioea?a?eaeueiiai aiaeiiao??ico. A oiae? i?iniaeoeaiiai ianoaaeaiiy aiaeineii?/ia ae?aaiinoeea ia??oiiaaeueiiai aiaeiiao??ico a?oiooaaeany ia eiinoaoaoe?? a?aeiieo oeiiaeo oa iaoeiiaeo iciae. Iaoeiia? iciaee aiaeiiao??ico aeyaeai? o eiaeii? aeanyoi? iaoe??ioee ? naia o oe??? a?oie oai?eo niinoa??aaany iaeineiioiiiee ia?aa?a caoai?thaaiiy. A oiae? eaia?ineii?? o oeeo oai?eo aoee ae?aaiinoiaai? aiaeiiao??i?aei? e?noe y?/iee?a oa iiaa?oiaa? iai?aiaioiaai? i/a?aaeii? aiaeiiao??i?aei? ?iieaioaoe ia oe? a?aenooiino? iciae ceoeiaiai i?ioeano a iaeiio oac?. Ca ?acoeueoaoaie ii?oieia?/iiai aeine?aeaeaiiy a?iioao?a iaoeiiaeo aiaieu aiaeiiao??ico o an?o aeiaaeeao i?aeoaa?aeaeaii a?noieia?/i? iciaee caoai?thaaiiy. O oai?eo c eeane/iei ia?aa?aii aiaeiiao??ico ???-?V noaae?? aeyaeai? i?aiaioiaai? aiaieua c iciaeaie ?io?eueo?aoe?? a ioi/oth/? oeaieie, eieae?ciaai? ia i/a?aaei?, e?eaeiai-iaoeiaeo cacyceao, iaeiia?/i? oa aeaia?/i? aiaeiiao??i?aei? e?noe y?/iee?a, a oaeiae ae?aciee ceoeiaee i?ioean. Oaeei /eiii ?acoeueoaoe i?iaaaeaieo iaie aeine?aeaeaiue ocaiaeaeothoueny c aeoieith a?eueoino? aaoi??a (A.?. A?euaiei, 1994; A.I. No?eaeaeia, A.E. Aeaauaeia, 1996; A.I. Caii?iaeai, 1998), ca?aeii yei? canoinoaaiiy eaia?ineii?? aeicaiey? ia eeoa c aenieith oi/i?noth ?aeaioeo?eoaaoe aiaieua aiaeiiao??ico, aea e ccynoaaoe i?e/eio o?ii?/iiai oaciaiai aieth oa aacie?aeiino?. A iao /an, ca aeoieith a?eueoino? aaoi??a, ?aeeiei ?aaeeeaeueiei iaoiaeii e?eoaaiiy aiaeiiao??ico ? o??o?a?/iee. A oie aea /an aeaye? aeine?aeieee aei iia?aoe?? (F. Clerckx et al., 1990; K.M. Silverberg , 1992; J. Donnez et al., 1994), a a?eueo?noue – i?ney o??o?a?/iiai ao?o/aiiy aeei?enoiaothoue ai?iiiaeueio oa?ai?th (E.A. Aaeaiyi, 1997; J.A. Rock, 1992; D.B. Redwine, 1993; E.J. Thomas, 1995). Noia?a/eeaei ? ieoaiiy i?i iaiao?aei?noue i?ecia/aiiy i?neyiia?aoe?eii? ai?iiiaeueii? oa?ai?? ae?ieai c aacie?aei?noth. O cacyceo c oeei aeieeea iaiao?aei?noue ia?aaeyaeo oaeoeee e?eoaaiiy oyaeeeo oi?i aiaeiiao??ico c o?aooaaiiyi ?iaeea?aeoaeueieo iniaeeainoae oai?eo, ee?i?ei-aiaoii?/ii? oa?aeoa?enoeee aiaeiiao??i?aeieo o?aaeaiue, ?ioiieia?/ieo oa ai?iiiaeueieo ii?ooaiue. I?e aeai?? iaoiaeo e?eoaaiiy ie aeio?eioaaeeny aeeoa?aioe?eiaaiiai i?aeoiaeo, yeee iieyaaa o aecia/aii? oaeoeee a?ae?aco i?ney eaia?ineii?/iiai ooi/iaiiy ae?aaiico, ioe?iee aiaoiii-oiiia?ao?/ieo iniaeeainoae aiaeiiao??ico oa i?iaaaeaiiy o??o?a?/iiai ao?o/aiiy. Aei ia?oi? a?oie oai?eo (? a?. – 51 ae?iea) aoee a?aeianai? iaoe??ioee, ye? i?aeeyaaee eeoa eaia?ineii?/iiio e?eoaaiith, o aeiaaeeao aeaeaeaiiy an?o aeaeeieo aiaeiiao??i?aeieo ?iieaioao?a i?ae /an iia?aoe?? oa i?e iayaiino? i?ioeiieacaiue aei i?ecia/aiiy ai?iiiiiiaeoethth/i? oa?ai??. Canoiniaoaaeenue Nd-YAG – eaca?ia (?A a?oia – 29 oai?eo) oa aeaeo?io??o?a?/ia (?A a?oia - 22 oai??) iia?aoeai? iaoiaeeee. Aei ae?oai? a?oie (?? a?. – 59 iaoe??ioie) aoee a?aeianai? oai?? c aeeaieeie aiaeiiao??i?aeieie ?iieaioaoaie o ae?eyioe? no?iie oaciaeo i?aai?a, ?aeoiaaa?iaeueii? i?aai?iaeee, o yeeo oe?eeiaeoiai c?oeioaaiiy aiaeiiao??i?aeieo ina?aaee?a eaia?ineii?/iei oeyoii ia aaeaeinue aeinyaiooe. ?i aoei i?iaaaeaia eiia?iiaaia e?eoaaiiy, yea aeeth/aei iia?aoeaio eaia?ineii?th ?c canoinoaaiiyi eaca?ii? (??A a?oia – 30 oai?eo) oa aeaeo?io??o?a?/ii? (??A a?oia – 29 oai?eo) iia?aoeaii? oaoi?ee ? i?neyiia?aoe?eio iaaeeeaiaioicio oa?ai?th ?c canoinoaaiiyi i?aia?aoo c a?oie aaii?no?a aiiaaeio?ii?i-?ee?ceia-ai?iiio (Ai?A) aica?ae?io (Cieaaeaen, ZENECA) o aeic? 3,6ia 1 ?ac a 28 aei?a ia i?ioyc? 3-o i?nyoe?a.Ie iiaiaeaeo?iiny c aeoieith Thomas E.J.(1992), yeee noaaeoue i?ae noii?a aeioe?euei?noue i?iaaaeaiiy eo?n?a ai?iiiaeueii? oa?ai?? o?eaae?noth a?eueo i?ae 3 i?nyoe?, oae ye ?niothoue aeai? (Brisens I.A., 1987) i?i oa, ui i?e?ineii?/i? aioo??oiueiee?oeii? ci?ie o aiaieuao aiaeiiao??ico ianoathoue oaea ia ae?oaiio i?nyoe? e?eoaaiiy. A ieoaii? aeai?o iac?io iia?aoeaiiai ao?o/aiiy a inoaii? ?iee aaniethoia a?eueo?noue aaoi??a aeneiaeththoue aeoieo, ui iaa?oue i?e iioe?aieo oi?iao aiaeiiao??ico ne?ae, ii iiaeeeaino?, aeio?eioaaoenue i?eioeeio ?aeiino?oeoeaii-ieanoe/ii? eiina?aaoeaii? o??o?a??. Oea iniaeeai aaaeeeai aeey iaoe??ioie ?ai?iaeoeoeaiiai a?eo, caoe?eaaeaieo o caa?aaeaii? aai a?aeiiaeaii? ?ai?iaeoeoeaii? ooieoe??. Oeae i?eioeei aeei?enoaiee iaie i?e iia?aoeaiiio eaia?ineii?/iiio e?eoaaii? ?c canoinoaaiiyi eaca?ii? (Nd-YAG eaca?) oa aeaeo?io??o?a?/ii? oaoi?ee. Iac?i ao?o/aiiy aecia/aee ca oa?aeoa?ii oa nooiaiai iioe?aiiy iaoieia?/iiai i?ioeano. A?i aeeth/aa aeano?oeoe?th aiaeiiao??i?aeieo ?iieaioao?a, aen?/aiiy aaoa?ioii?e c ianooiiith eiaaoeyoe??th eiaea, ?icn?/aiiy i?aeoeaieiieo c?iuaiue, ?acaeoe?th aai aeaeaeaiiy y?/iee?a. A?noa?aeoii?y iaie i?iaaaeaia o 17 ae?iie a?eii iiiaae 35 ?ie?a. Aei aeaeaeaiiy iaoee aaeaaaeeny ca oiiae a?aenooiino? o oai?eo ?ai?iaeoeoeaieo iai???a o aeiaaeeao ?ao?ioea?a?eaeueiiai aiaeiiao??ico, ii?aeiaiiy ciai?oiueiai aiaeiiao??ico IV noaae?? c aaeaiii?icii, iayaiino? i?ioeiieacaiue aei i?ecia/aiiy ai?iiiaeueii? oa?ai?? oa i?e ii?aeiaii? oyaeeiai aiaeiiao??ico c noiooiueith a?iaeieia?/iith iaoieia??th. I?e o?aaeaii? noi?aeieo i?aai?a ie?ai? aaoi?e aaaaeathoue ca aeioe?eueia i?iaiaeeoe aeaeaeaiiy aiaeiiao??i?aeieo ?iieaioao?a c ?acaeoe??th ii?iaeieiieo i?aai?a [A.E. E?aniiiieueneee, 1998, A.A. Aaeaiyi, 1998].I?ioa a?aoiaoth/e aenieo o?aaiaoe/i?noue oaeeo iia?aoe?e ie aeio?eioaaeenue ?ioi? oaeoeee ? aeeiioaaee iaeneiaeueii iiaeeeaa aeaeaeaiiy aiaeiiao??i?aeiiai ?iieaioaoo aac i?iieeiaiiy a ii?iaeieio noi?aeiiai i?aaia c ianooiiei i?ecia/aiiyi ai?iiiaeueii? oa?ai??. *anoioa ?io?aiia?aoe?eieo oa ?aii?o i?neyiia?aoe?eieo oneeaaeiaiue i?e i?iaaaeaii? eaia?ineii?/ieo ao?o/aiue aoea i?i?iaeueiith ? noaiiaeea iaio i?ae 1%. No?oeoo?a oneeaaeiaiue i?neyiia?aoe?eii? oa?ai?? cieaaeaenii aoea i?aaenoaaeaia aeayeeie iia?/ieie aoaeoaie (i?eeeae aea?o, i?aeaeuaia aiioe?eia eaa?euei?noue). Iaeiae oea ia aeiaaaei a?aei?ie i?aia?aoo. Ia aeaiee /an a?eueo?noue aeine?aeiee?a iniiaiei e?eoa???i aoaeoeaiino? e?eoaaiiy aiaeiiao??ico aaaaeathoue /anoioo ?aoeeaeea?a caoai?thaaiiy oa ii?iae?caoe?th aaia?aoeaii? ooieoe??. Aeei?enoaia iaie ye?nia ioe?iea aieueiaiai neiae?iio o aeaeyae? A? aeaea ciiao iac?eoecoaaoe ee?i?/io aoaeoeai?noue ??cieo iaoiae?a e?eoaaiiy. Oi?iaeiaae o?ueioi?ny/iiai oa?i?io niinoa?aaeaiiy eiinoaoiaaii /?oea oa aeinoia??ia ciaioaiiy A? iacaeaaeii a?ae iaoiaeo e?eoaaiiy. I?ioa aaea /a?ac i?a?ieo niinoa??aa?oueny i/aaeaeia cieaeaiiy A? o oai?eo, ye? iaea?aeoaaee eiia?iiaaia e?eoaaiiy a ii??aiyii? c a?oiith, o ye?e i?ney iia?aoe?? ai?iiiiiiaeoethth/a oa?ai?y ia i?ecia/aeany. Iiaia e?ea?aeaoe?y aieueiaiai neiae?iio i?ney eiia?iiaaiiai e?eoaaiiy niinoa??aaeanue o 52,5% , a i?ney eaia?ineii?/iiai - o 41,2% aeiaaeeao. Aea eiai ?ioaineai?noue o an?o oai?eo aoea cia/ii ieae/ith, i?ae aei e?eoaaiiy. Io?eiai? iaie aeai? na?ae/aoue i?i oa, ui eiia?iiaaia oa?ai?y o ii??aiyii? c eaia?ineii?/iei e?eoaaiiyi ca iaeiaeiaeo oiia oa iaeiaeiaiio iac?i? iia?aoeaiiai ao?o/aiiy o oai?eo c aiaeiiao??icii ???-?V noaae?? ca aieeaii ia aieueiaee neiae?ii a?eueo aoaeoeai?oa (?<0,05). Oea iiaeia iiynieoe oei, ui iaa?oue i?e aenie?e oaoi?oe? oa aaeineiiaeaiino? iia?aoeaiiai e?eoaaiiy i?e oyaeeeo oi?iao aiaeiiao??ico caa??aa?oueny aenieee ?ecee ?aoeeaeeao caoai?thaaiiy. Canoinoaaiiy aaii?no?a Ai?A a cia/i?e i??? ciaioo? oeth iaaaciaeo, oi/a iiai?noth ia aeeeth/a?. Aiae?c a?aeaeaeaieo ?acoeueoao?a cai?iiiiiaaieo iaoiae?a e?eoaaiiy iieacaa, ui /anoioa ?aoeeaeea?a caoai?thaaiiy a ? a?oi? (28,3%) ia?aaeuo? aiaeia?/iee iieaciee a ?? a?oi? (19,03%)(?<0,05), ui i?aeoaa?aeaeo?oueny ?acoeueoaoaie iiaoi?ii? eaia?ineii??. Iiaoi?ia eaia?ineii?y aoea i?iaaaeaia 38 oai?ei c ??? oa ?V noaae??th aiaeiiao??ico /a?ac 6-12 i?nyoe?a i?ney e?eoaaiiy, c ieo i?ney iia?aoeaiiai eaia?ineii?/iiai 23 (45,1%), eiia?iiaaiiai – 15 (25,4%). Iieacaiiyie aeey iiaoi?ii? eaia?ineii?? noaee aacie?aei?noue (50,7% aeiaaee?a); a?aeiiaeaiiy aieueiaiai neiae?iio (52,6% aeiaaee?a); iayai?noue ?aoeeaeeaieo iooeeiieo ooai?aiue o iaeiio oac? (21,1% aeiaaee?a). Iiaoi?ia eaia?ineii?y aeaea ciiao aeyaeoe ?aoeeaeea aiaeiiao??i?aeiiai iaoieia?/iiai i?ioeano o 23 (60,5%) ?c 38 oai?eo, ui noaiiaeoue 20,9% i?ie?eiaaieo iaoe??ioie. I?ae?aooiie noie aae?a aiaeiiao??i?aeieo o?aaeaiue ca oeaeith AOO i?ae /an iiaoi?ii? eaia?ineii?? ? ii??aiyiiy iaea?aeaieo aeaieo c aeo?aeieie na?ae/eoue i?i ciaioaiiy noie aae?a ia 59,4% i?e canoinoaaii? eiia?iiaaii? oa?ai?? oa ia 43,6% i?e aeei?enoaii? eeoa iia?aoeaiiai eaia?ineii?/iiai e?eoaaiiy. ?nio? caeaaei?noue /anoioe ?aoeeaeea?a a?ae eieae?caoe?? aiaeiiao??i?aeieo aaoa?ioii?e. Oae ?aoeeaeeae caoai?thaaiiy a?eueoa i?ae aaea?/? /ano?o? i?e ?ao?ioea?a?eaeuei?e eiai eieae?caoe??. Niinoa??aa?oueny o?niee cacycie ?aoeeaeeao caoai?thaaiiy oa ae?aaeaiino? ceoeiaiai i?ioeano c aeei?enoaiith iaoiaeeeith eaia?ineii?/iiai iia?aoeaiiai ao?o/aiiy. Aeinoia??ii e?auee ?acoeueoao aea? canoinoaaiiy eaca?a, ia ui aeaco? iaeaea a 1,5 ?ace ieae/a /anoioa ?aoeeaeea?a oa ia 25% ieae/a /anoioa i?neyiia?aoe?eiiai ceoeiooai?aiiy. Eiia?iiaaia e?eoaaiiy ?c canoinoaaiiyi cieaaeaeno aeaei ciiao cieceoe /anoioo ii?ooaiue iaino?oaeueii? ooieoe?? aei ??aiy iaeaea a 1,4 ?ace ieae/iai (c 84,7% aei 27,1%), i?ae a ?acoeueoao? eeoa eaia?ineii?/iiai e?eoaaiiy (c 86,3% aei 37,3%). ?c 61 ianoaaeaii? oai?i? c aacie?aei?noth 43(70,5%) aoee caoe?eaaeai? o a?aeiiaeaii? oa?oeeueiino?. I?e noaoenoe/iiio aiae?c? aeinoia??ii? ??cieoe? a /anoio? ianoaiiy aaa?oiino? i?ney eaia?ineii?/iiai e?eoaaiiy (29,3%) oa eiia?iaoe?? eiai c cieaaeaenii (31,5%) ia aeyaeaii. I?ioa ?nio? nooo?aa ??cieoey a aeeiai?oe? ianoaiiy aaa?oiino?. Oae i?e eaia?ineii?/iiio e?eoaaii? iaeneiaeueia e?euee?noue aaa?oiinoae niinoa??aa?oueny ia 6-9 i?nyoe? niinoa?aaeaiiy, a i?e eiia?iiaaiiio ia 9-12 i?n. Nd-YAG – eaca?iee iaoiae eaia?ineii?/iiai e?eoaaiiy oa?aeoa?ecothoue aeaui e?au? iieacieee a?aeiiaeaiiy oa?oeeueiino? (32%) a ii??aiyii? c aeaeo?io??o?a?/iei iaoiaeii (27,7%), i?ioa ??cieoey a noia?i?e aoaeoeaiino? iacia/ia. Aiaeia?/i? ?acoeueoaoe (33%) iaaaaeai? a ?iaioao E.A. Aaeaiyi, A.?. Eoeaeiaa (1998). I?ioa iao? aeai? iinooiathoueny ?acoeueoaoai, ye? iaaiaeyoue S.Bianci et al. (1996). Canoiniaoth/e eiia?iiaaio oa?ai?th c aaii?noaie Ai?A ?i aaeaeiny i?aeaeueoe /anoioo ianoaiiy aaa?oiino? o oai?eo c aiaeiiao??icii aei 49,3%. Iaea?aeai? iaie ?acoeueoaoe na?ae/aoue i?i iiaeeea?noue i?iaaaeaiiy eeoa iia?aoeaiiai eaia?ineii?/iiai e?eoaaiiy aiaeiiao??ico ???-?V noaae?? o oai?eo c aacie?aei?noth. Aea ca oiiae iayaiino? aeeaieeo aiaeiiao??i?aeieo ?iieaioao?a o ae?eyioe? no?iie oaciaeo i?aai?a ? ?aeoiaaa?iaeueii? ia?aai?iaeee iaoiaeii aeai?o ? eiia?iiaaia e?eoaaiiy c aeei?enoaiiyi i?ney iia?aoe?? aaii?no?a Ai?A. Cai?iiiiiaaia iaie e?eoaaiiy iaei iaiaeiicia/iee oa ??ciia?/iee aieea ia ?ioiiee aiiainoac (?en. 1). ?en. 1 Ci?ia iieaciee?a O- oa A-nenoai o oai?eo c aiaeiiao??icii ???-?V noaae?? a ?acoeueoao? canoinoaaiiy ??cieo iaoiae?a e?eoaaiiy. Ia caaaeueio iiioeyoe?th O-e?ioioeeo?a oa ?o noaiiioeyoe?? ye eaca?ia, oae ? aeaeo?io??o?a?/ia e?eoaaiiy ia caaaeaaaei noaoenoe/ii aeinoia??iiai aieeao. Iaie anoaiiaeaii, ui nooo?ai i?aeaeuaiee aeo?aeiee ??aaiue A-e?ioioeeo?a caa??aa?oueny. I?ioa i?ney eaca?ii? iaoiaeeee iia?aoeaiiai e?eoaaiiy ia a?aei?io a?ae aeaeo?io??o?a?/ii? niinoa??aaeanue ii?iae?caoe?y aoii?aeueiiai ?ioi?oaoo, ui noi?iaiaeaeo?oueny ciaioaiiyi ai?noo Ig A oa Ig G aei ??aiy i?aeoe/ii caei?iaeo. ?ioa ea?oeia niinoa??aaeanue i?e aeei?enoaii? iaie ai?iiiaeueii? oa?ai?? a ii?aeiaii? c eaca?iei eaia?ineii?/iei ao?o/aiiyi. Aeyaeaii ii?iae?caoe?th iieaciee?a ye ee?oeiiiai, oae ? aoii?aeueiiai ?ioi?oaoo. Aeinoia??ii i?aeaeuoaaany aaniethoiee ai?no O-e?ioioeeo?a oa oaeia?ii? ?o noaiiioeyoe??. Ca ?aooiie oeueiai ni?aa?aeiioaiiy Om/Og a oe?e a?oi? oai?eo aeinoia??ii i?aeaeueeinue. C aieo aoii?aeueiiai ?ioi?oaoo a?aei?/aii aeinoia??ia cieaeaiiy A-e?ioioeeo?a, ??aiy ?ioiiaeiaoe?i?a oa eiioeaio?aoe?? Oe?E. Oaeei /eiii, ei?aeoe?y ?ioiiiai aiiainoaco iaea?eueo aoaeoeaia i?e aeei?enoaii? a e?eoaaii? aiaeiiao??ico ???-?V noaae?? eiia?iiaaiiai e?eoaaiiy ?c canoinoaaiiyi aiaeineii?/ii? eaca?ii? iaoiaeeee. Ca aieeaii ia ai?iiiaeueiee aiiainoac a?eueo nooo?a? iiceoeai? c?ooaiiy a?aei?/aeeny i?e aeei?enoaii? eaia?ineii?/iiai e?eoaaiiy. I?e oeueiio eaca?ia iia?aoeaia oaoi?ea ia? aeayeo ia?aaaao iaae aeaeo?io??o?a?/iith (?en. 2). Eiia?iiaaia oa?ai?y ni?e/eithaaea i?eai?/aiiy ooieoe?? a?iioaeaii-a?iio?ca?ii-y?/ieeiai? nenoaie, ui i?iyaeyeiny ae?aciei cieaeaiiyi ai?noo y?/ieeiaeo oa aiiaaeio?iiieo ai?iii?a oi?iaeiaae 1-3 i?n. i?ney eiai cae?i/aiiy. Iiceoeaiee aoaeo eiia?iiaaiiai e?eoaaiiy a?aei?/aany i?ney cae?i/aiiy aaeuei?aiiai aieeao aaii?no?a Ai?A, ui noi?iaiaeaeoaaeinue iaaeeaeaiiyi oeeo iieaciee?a aei eiio?ieth oa a?aeiiaeaiiyi ?ai?iaeoeoeaii? ooieoe??. Ca ?acoeueoaoaie aeanieo aeine?aeaeaiue oa a?aoiaoth/e aeai? e?oa?aoo?e iaie ?ic?iaeaiee aeai?eoi aaaeaiiy oai?eo ?c ciai?oi?i aiaeiiao??icii ???-?V noaae?? (?en. 3). Ie aaaaea?ii iaiacyceiaei i?iaaaeaiiy eaia?ineii??, ui aeicaiey? ooi/ieoe ae?aaiic, iaea?aeaoe a?noieia?/iee aeniiaie, ae?iaeoe oaeoeeo iiaeaeueoiai e?eoaaiiy oa i?iaanoe eiai ia?oee, iia?aoeaiee aoai, aaaeaii ?c canoinoaaiiyi eaca?ii? oaoi?ee. Iac?i aiaeio??o?a?/iiai iia?aoeaiiai ao?o/aiiy oa eiai eiia?iaoe?y c ai?iiiiiiaeoethth/ith oa?ai??th aecia/aeeny nooiaiai iioe?aiiy iaoieia?/iiai i?ioeano, a?eii oai?i?, ?ai?iaeoeoeaieie iai??aie, noiooiueith iaoieia??th. O iieiaeeo ae?iie, caoe?eaaeaieo o caa?aaeaii? oa?oeeueiino?, aeioe?eueii iaiaaeeoenue iia?aoeaiei eaia?ineii?/iei e?eoaaiiyi i?e iiaeeeaino? aeaeaeaiiy an?o aeaeeieo aiaeiiao??i?aeieo aaoa?ioii?e ?c iaeii/aniei a?aeiiaeaiiyi ii?iaeueieo aiaoii?/ieo aca?iia?aeiinei a ii?iaeiei? oaca. I?e iayaiino? aeeaieeo aiaeiiao??i?aeieo ?iieaioao?a o ae?eyioe? no?iie oaciaeo i?aai?a, ?aeoiaaa?iaeueii? ia?aai?iaeee oa ca a?aenooiino? aiaaiaiino? a?aeiinii oe?eeiaeoiai c?oeioaaiiy aiaeiiao??i?aeieo ina?aaee?a eaia?ineii?/iei oeyoii aeioe?eueiei ? i?ecia/aiiy a i?neyiia?aoe?eiiio ia??iae? aaii?no?a Ai?A. ?en. 2 Ci?ia iieaciee?a noaoaaeo ai?iii?a o oai?eo c aiaeiiao??icii ???-?V noaae?? a ?acoeueoao? canoinoaaiiy ??cieo iaoiae?a e?eoaaiiy. I?e aeai?? iac?io eaia?ineii?/iiai ao?o/aiiy o ae?iie aac ?ai?iaeoeoeaieo iai???a ea?oaaeeny a?eii oa oa?aeoa?ii iaoieia?/iiai i?ioeano. ?en. 3 Aeai?eoi aaaeaiiy oai?eo c aiaeiiao??icii ???-?V noaae?? O oai?eo aei 35 ?ie?a ii iiaeeeaino? aeio?eioaaeeny i?eioeeio ?aeiino?oeoeaii-ieanoe/ii? eiina?aaoeaii? o??o?a?? ? aaeaaaeenue aei ?aaeeeaeueieo iia?aoe?e o ae?iie i?ney 35 ?ie?a o aeiaaeeao o?aaeaiiy noi?aeieo i?aai?a oa iayaiino? noiooiuei? iaoieia??. An?i oai?ei, ia caoe?eaaeaiei o caa?aaeaii? oa?oeeueiino?, a i?neyiia?aoe?eiiio ia??iae? i?ecia/aeany ai?iiiaeueia oa?ai?y. Ee?i?/ia aoaeoeai?noue cai?iiiiiaaiiai iaie iaoiaeo aeeoa?aioe?eiaaiiai i?aeoiaeo o aeai?? oaeoeee e?eoaaiiy oa?aeoa?eco?oueny ca?eueoaiiyi /anoioe ianoaiiy aaa?oiino? oa cieaeaiiyi ?aoeeaeea?a o oai?eo c oyaeeei aiaeiiao??icii. AENIIAEE 1. Eaia?ineii?y a ii??aiyii? c ?ioeie ?iaaceaieie oa ia?iaaceaieie iaoiaeaie ae?aaiinoeee ? iaea?eueo ?ioi?iaoeaiei caniaii aea/aiiy eieae?caoe?? aiaeiiao??i?aeieo aaoa?ioii?e, aa?eo?eaoe?? oeiiaeo oa aoeiiaeo oi?i ciai?oiueiai aiaeiiao??ico ia o?eueee i?e ?-??, a ? a ??? oa ?V noaae??. 2. O oai?eo c aiaeiiao??icii ??? oa ?V noaae?? a ii??aiyii? c i?aeoe/ii caei?iaeie ae?ieaie niinoa??aa?oueny ciaioaiiy ??aiy i?iaanoa?iio o ne?iaaooe? e?ia?, yea o 70% iaoe??ioie ee?i?/ii i?iyaey?oueny aeaoaeoii ethoa?iiai? oace iaino?oaeueiiai oeeeeo, oa iathoue i?noea iciaee i?eai?/aiiy O-ee?oeiii? eaiee ?ioi?oaoo ( cieaeaiiy ai?noo Ocaa, Oi?ia?aiy Oieaie ? aeoeaaoe?? aoii?aeueiiai (Acaa, Ig A,G, Oe?E) ?ioi?oaoo. 3. Canoinoaaiiy eiia?iiaaiiai e?eoaaiiy o oai?eo c oyaeeeie oi?iaie aiaeiiao??ico ni?ey? iie?auaiith iieaciee?a aeoeaiino? ee?oeiiiai ?ioi?oaoo (OA___i___?Ob_____!Ub?e i??? – aoii?aeueiiai (Acaa, Oe?E), noi?iaiaeaeo?oueny ei?ioei/aniei (aea cai?ioi?i) cieaeaiiyi noa?i?aeiaaiaco a y?/ieeao, ui ee?i?/ii i?iyaey?oueny a?eueo o?eaaeith a ii??aiyii? c o??o?a?/iei e?eoaaiiyi ?ai?n??th caoai?thaaiiy, aea a??oith aeeiai?eith a?aeiiaeaiiy ?ai?iaeoeoeaii? ooieoe??. 4. Aeei?enoaiiy Nd-YAG eaca?a a aiaeineii?/iiio e?eoaaii? aiaeiiao??ico ??? oa ?V noaae?? a ii??aiyii? c aeaeo?io??o?a?/iith iaoiaeeeith iia?aoe?? ni?ey? ciaioaiith /anoioe i?neyiia?aoe?eiiai ceoeiooai?aiiy ia 25% ? ?aoeeaeeao caoai?thaaiiy o 1,5 ?ace oa iiacycaia c? ciaioaiiyi ?eceeo ?io?a- oa i?neyiia?aoe?eieo oneeaaeiaiue ia 30%. 5. Canoinoaaiiy e?eoaaeueiiai aeai?eoio o oai?eo c aiaeiiao??icii ??? oa ?V noaae??, yeee ia?aaeaa/o? aeeoa?aioe?eiaaia aeei?enoaiiy eiia?iiaaiiai oa aiaeineii?/iiai iaoiae?a e?eoaaiiy ? eaca?ii? oa aeaeo?io??o?a?/ii? iia?aoeaii? oaoi?ee c o?aooaaiiyi a?eo iaoe??ioee, ?ai?iaeoeoeaieo iai???a, iniaeeainoae eieae?caoe?? aiaeiiao??i?aeieo aaoa?ioii?e, iayaiino? noiooiuei? a?iaeieia?/ii? iaoieia??, ni?ey? iie?auaiith ?aii?o i?neyiia?aoe?eieo oa a?aeaeaeaieo ?acoeueoao?a e?eoaaiiy. I?AEOE*I? ?AEIIAIAeAOe?? 1. Aea?? e?eoaaeueii? oaeoeee o oai?eo c aiaeiiao??icii ???-IV noaae?? ne?ae i?iaiaeeoe ca aeeoa?aioe?eiaaiei i?eioeeiii, c o?aooaaiiyi a?eo iaoe??ioee, ?ai?iaeoeoeaieo iai???a, iniaeeainoae eieae?caoe?? aiaeiiao??i?aeieo aaoa?ioii?e, iayaiino? noiooiuei? a?iaeieia?/ii? iaoieia??. 2. Ca oiiae iayaiino? aeeaieeo aiaeiiao??i?aeieo ?iieaioao?a o ae?eyioe? no?iie ii?iaeienoeo i?aai?a, ?aeoiaaa?iaeueii? ia?aai?iaeee, iiaeiii aooe canoiniaaia eiia?iiaaia e?eoaaiiy c i?neyiia?aoe?eiei aeei?enoaiiyi aaii?no?a Ai?A. 3. AE?ieai, caoe?eaaeaiei o a?aeiiaeaii? oa caa?aaeaii? ?ai?iaeoeoeaii? ooieoe??, iiaeeeaa i?iaaaeaiiy eeoa eaia?ineii?/iiai e?eoaaiiy. NIENIE IIOAE?EIAAIEO ?IA?O CA OAIITH AeENA?OAOe?? 1. Eaia?ineiie/aneia e eiiaeie?iaaiiia ea/aiea aanieiaeiuo aieueiuo n yiaeiiao?eicii // A?niee ii?nueei? iaaeeoeeie.-1999.-?2.-N.16-18 2. Aiaeineii?/ia o??o?a?y a a?iaeieia?/i?e i?aeoeoe? // Oieoaeueia o??o?a?y. -1998.-?4.-N.32-40 (ni?aaao Caii?iaeai A.I., ?iaeeianueea I.I., Aeaae/oe ?.C. ) 3. Eaia?ineii?/ia e?eoaaiiy aiaeiiao??ico: no/ania e iaeaooi? // Iaeanueeee iaaee/iee aeo?iae. –1998.-?3.-N. 7-9 (ni?aaao. Iaii?aaea N.I., Naiei I. I.) 4. ?ieue iia?aoeaiie e iiaoi?iie eaia?ineiiee a ea/aiee aaieoaeueiiai yiaeiiao?eica // A?niee ii?nueei? iaaeeoeeie.-1998.-?4.-N.45-48 (niaao. Aeaae/oe E.C., Aieyineay A.A.) 5. Ci?ie aiioe?eii-aaaaoaoeaiiai noaio o aacie?aeieo oai?eo c oyaeeei aiaeiiao??icii i?ney iia?aoeaii? eaia?ineii?? oa eiia?iiaaiiai e?eoaaiiy // A?niee ii?nueei? iaaeeoeeie.-1999.-?3.-N.109-111 (ni?aaao. Aeaae/oe ?.C., Aieyinueea A.A.) 6. Canoinoaaiiy ?oe?aeo o i?ia?ai? aeiiii?aeieo ?ai?iaeoeoeaieo oaoiieia?e i?e ii?aeiai?e oeai?ae?eii-oieniieaciia?e ?ioaeoe?? // Aanieiaeea: aniiiiaaoaeueiua ?ai?iaeoeoeaiua oaoiieiaee: Na.iao/iuo o?oaeia.-1999.-N.205-206 (niaao. Caii?iaeai A.I., A?ooaoeueea I.A., Niaie?a ?.A.) 7. Aeeooa?aioeeaeueiay aenoa?ineiie/aneay aeeaaiinoeea ceiea/anoaaiiuo e aeia?iea/anoaaiiuo i?ioeannia yiaeiiao?ey // Iaoa?. ?? ?inneeneie iao/ii-i?aeoe/aneie eiioa?aioeee “I?iaeaiu yiaeineiiee a aeiaeieiaee”.-1995.-N.109-110 (niaao. Ua?aeia A.A.) AIIOAOe?? Iicaiaie .. Eaia?ineiie/aneia eiiaeie?iaaiiia aaiienoaie aiiaaeio?iiei-?eeeceia ai?iiia ea/aiea aieueiuo yiaeiiao?eicii –IV noaaeee. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/?iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.01. - aeooa?noai aeiaeieiaey. – Iaeanneee iaaeeoeeineee oieaa?neoao Oe?aeiu, Iaeanna, 1999. Aeenna?oaoeey iinayuaia i?iaeaia oniaa?oainoaiaaiey aeeaaiinoeee ea/aiey aieueiuo n yiaeiiao?eicii -?V noaaeee .Ii iaoa?eaeai auyaeaiu iniaaiiinoe no?oeoo?u eaia?ineiie/aneiai iia?aoeaiiai eiiaeie?iaaiiiai , ioeaiaii aeeaaiinoe/aneia cia/aiea eaia?ineiiee. Eco/aiu eiioiiua, ai?iiiaeueiua ia?ooaiey o aeaiuei n yiaeiiao?eicii -?V noaaeee aei e iinea ea/aiey, aeeaeaeoea a caaeneiinoe iaoiaea oeia i?eiai?iiie iia?aoeaiie . Yooaeoeaiinoue i?eiaiaiiie oa?aiee ioeaieaaeanue ii aeeiaieea eeeie/aneeo i?iyaeaiee, eciaiaieyi eiioiiiai e ai?iiiaeueiiai noaoona, /anoioa ianooieaiey aa?aiaiiinoae e aicieeiiaaiey ?aoeeaeeaia, aeaiiui eiio?ieueiuo eaia?ineiiee . Ioia/aii oeo/oaiea ?acoeueoaoia ea/aiey i?e eniieueciaaiee eaca?iie iia?aoeaiie oaoieee a n?aaiaiee n yeaeo?ioe?o?ae/aneie. Onoaiiaeaii, /oi i?eiaiaiea iineaiia?aoeeiiiii ia?eiaea aaiienoia niinianoaoao /anoiou ?aoeeaeeaia ainnoaiiaeaiea neiae?iia. O aieueiuo ?ai?iaeoeoeaiuie aiciiaeii eniieueciaaiea eeoue eaia?ineiie/aneiai oe?o?ae/aneiai , aeoaieeo yiaeiiao?eieaeiuo eiieaioaoia ia noaieao i?aaiia, ?aeoiaaaeiaeueiie ia?aai?iaeea i?e ionoonoaee oaa?aiiinoe iieiii oaeaeaiee yiaeiiao?eieaeiuo aaoa?ioiiee eaia?ineiie/aneei oeaeaniia?acii i?iaiaeeoue eiiaeie?iaaiioth aaiienoaie oa?aieth. ?ac?aaioai ai?iae?iaai aeai?eoi aeeooa?aioee?iaaiiiai iiaeoiaea e i?eiaiaieth eaia?ineiie/aneiai e eiiaeie?iaaiiiai eniieueciaaieai aaiienoia aiiaaeio?iiei-?eeeceia ai?iiia (cieaaeaena) iaoiaeia aieueiuo yiaeiiao?eicii –IV noaaeee, i?e eioi?ii o/eouaaaony iaoeeaioee, ?ai?iaeoeoeaiua , iniaaiiinoe eieaeecaoeee i/aaia yiaeiiao?eica, niioonoaothuay iaoieiaey. Eeth/aaua neiaa: yiaeiiao?eic, aeeaaiinoeea, eaia?ineiiey, yiaeioe?o?ae/aneia , eiiaeie?iaaiiia . Iicaiaee TH.N. Eaia?ineii?/ia oa eiia?iiaaia c aaii?noaie aiiaaeio?ii?i-?ee?ceia ai?iiio e?eoaaiiy oai?eo c aiaeiiao??icii ???-?V noaae??. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.01. - aeooa?noai oa a?iaeieia?y. – Iaeanueeee aea?aeaaiee iaaee/iee oi?aa?neoao IIC Oe?a?ie, Iaeana, 1999. Aeena?oaoe?y i?enay/aia i?iaeai? aaeineiiaeaiiy ae?aaiinoeee oa oaeoeee e?eoaaiiy oai?eo c aiaeiiao??icii ???-?V noaae??. Ca iaoa??aeaie aeine?aeaeaiue aeyaeai? iniaeeaino? no?oeoo?e iieacaiue aeey i?iaaaeaiiy eaia?ineii?/iiai iia?aoeaiiai oa eiia?iiaaiiai e?eoaaiiy, iieacaia ae?aaiinoe/ia ?ieue eaia?ineii??. Aea/aii ?ioii?, ai?iiiaeuei? c?ooaiiy, iaeaeeae/? oa a?aeaeaeai? ?acoeueoaoe caeaaeii a?ae iaoiaeo e?eoaaiiy oa oeio canoiniaaii? iia?aoeaii? oaoi?ee. ?ic?iaeaii oa ai?iaiaaii aeeoa?aioe?eiee i?aeo?ae aei canoinoaaiiy eaia?ineii?/iiai ? eiia?iiaaiiai c aeei?enoaiiyi aaii?no?a aiiaaeio?ii?i-?ee?ceia ai?iiio (cieaaeaeno) iaoiae?a e?eoaaiiy oai?eo aiaeiiao??icii ???-?V noaae??, yeee a?aoiao? a?e iaoe??ioee, ?ai?iaeoeoeai? iai??e, iniaeeaino? eieae?caoe?? ina?aaee?a aiaeiiao??ico, noiooith iaoieia?th. Eeth/ia? neiaa: aiaeiiao??ic, ae?aaiinoeea, eaia?ineii?y, aiaeio??o?a?/ia e?eoaaiiy, eiia?iiaaia e?eoaaiiy. Mozgovyy Yury Stepanovich . Laparoscopic and combined with agonist gonadotropin-releasing hormone treatment of patients suffering of severe endometriosis.-Manuscript. Thesis for the scientific degree of candidate of medical sciences by speciality 14.01.01.-obstetrics and gynecology.-Odessa State Medical University. Ministry of Health Care of Ukraine, Odesa, 1999. The thesis is devoted to perfection of diagnostics and treatment techniques of severe endometriosis. By the retrospective study reviews the peculiarities of the structure of indications for performing laparoscopic operative and combined treatment were revealed , the role of laparoscopic diagnostic is shown. There were studies of immune, hormonal disturbances, the nearest and follow-up results depending on treatment methods and type of used operative techniques. There was worked out and tested an individual approach to usage of laparoscopic and combined with agonist gonadotropin-releasing hormone (Zoladex) treatment of patients suffering of severe endometriosis taking into consideration the patient’s age, reproductive plans, particularities of localization of endometriosis areas, following pathology. Key words: endometriosis, diagnostic, laparoscopy, endosurgical treatment, combined treatment.

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