OE?A?INUeEEE IAeI AIIAeAIIIEIAI? OA IIOAEOeIEIEO OAI?IA

ii.E.A.A?IIAOAANUeEIAI IIC OE?A?IE

AIEIEIIIAA ETHAeIEEA AIAOIEI?AIA

OAeE 616.98:578.825.11]-053.36/.37-037-07

E?EOA?I? AeIAAIINOEEE OA IA?AAeAA*AIIss

IA?AAIAO AA?IAOE*II? IIENO-IIOAEOeI?

O AeIOAE ?AIIUeIAI AIEO

14.01.13 – iioaeoeieii oai?iae

AAOI?AOA?AO

aeena?oaoei? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1999

Aeena?oaoei?th ? ?oeiien

?iaioa aeeiiaia a Oa?eianueeiio iinoeoooi oaeineiiaeaiiy eiea?ia

Iaoeiaee ea?iaiee: eaiaeeaeao iaaee/ieo iaoe,

aeioeaio Iiuaiei Aieoi?iy Aiaoiei?aia

eaoaae?a aeeoy/eo iioaeoeieieo oai?ia

Oa?eianueeiai iinoeoooo oaeineiiaeaiiy eiea?ia

Ioioeieii iiiiaioe: aeieoi? iaaee/ieo iaoe,

i?ioani? Iinothe Aaiaoa Iaaiiaia,

caa. eaoaae?e aeeoy/eo iioaeoeieieo oai?ia Eueaianueeiai aea?aeaaiiai
iaaee/iiai oiiaa?neoaoo

aeieoi? iaaee/ieo iaoe, i?ioani? O?ioeiaa Eiy Ieaeni?aia eaoaae?a
aeeoy/eo iioaeoeieieo oai?ia Iaoeiiiaeueiiai iaaee/iiai oiiaa?neoaoo ii.
I.I.Aiaiiieueoey

I?iaiaeia onoaiiaa: Oa?eianueeee aea?aeaaiee iaaee/iee oiiaa?neoao

Caoeno aiaeaoaeaoueny «29» ea?oiy 1999 ? i 11.00 aiaeeii ia caniaeaiii
niaoeiaeiciaaii? a/aii? ?aaee Ae.26.614.01 Ee?anueeiai
iaoeiai-aeineiaeiiai iinoeoooo aiiaeaiiieiai? oa iioaeoeieieo oai?ia
ii. E.A.A?iiaoaanueeiai (2525015, i.Ee?a, aoe. Ni/iaaiai iianoaiiy, 23).
C aeena?oaoei?th iiaeia iciaeiieoenue o aiaeiioaoei Ee?anueeiai
iaoeiai-aeineiaeiiai iinoeoooo aiiaeaiiieiai? oa iioaeoeieieo oai?ia
ii. E.A.A?iiaoaanueeiai (2525015, i.Ee?a, aoe. Ni/iaaiai iianoaiiy, 23).

Aaoi?aoa?ao ?icineaiee «29» aa?aciy1999 ?ieo.

A/aiee nae?aoa?

niaoeiaeiciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe A.Ae.Aiae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue oaie. Aa?iaoe/iie iioaeoei?, ye i naiiio ai?ono
cae/aeiiai aa?iana (ACA), yeiai aoei aiaee?eoi aieueo iiae 70 ?ieia
oiio, i?eaeieyee cia/ii iaioa oaaae iiae iioei ai?oniei iioaeoeiyi.
Oieueee a inoaiii ?iee, caaaeyee oaeineiiaeaiith iaoiaeia aeiaaiinoeee,
c’yaeeanue iiaeeeainoue aeaoaeueiiai aea/aiiy iniaeeainoae ACA, oa noaea
c?icoiieith aaaeeeainoue i?iaeaie aa?iaoe/ii? iioaeoei?.

sse naiae/aoue aeaii AIIC, i?aaenoaaieee ai?onia aa?iana oe?iei
?iciianthaeaeaii na?aae ethaeae, ieie iioieiaaii aiae 60 aei 95%
ianaeaiiy Caiii? eoei.

Iioieoaaiiy aeioae ACA iiaea noaoeny aioaiaoaeueii, iio?aiaoaeueii, i?e
i?ioiaeaeaiii /a?ac iioieiaaii iieiaiai oeyoe oa iinoiaoaeueii, i?e
aaciina?aaeiueiio eiioaeoi c iioieiaaiith iaoi?’th aai iaaee/iei
ia?niiaeii.

Aa?iaoe/ia iioaeoeiy o aeioae ?aiiueiai aieo iiaea ia?aaiaaoe o aeaeyaei
eieaeiciaaii? oa aaii?aeiciaaii? oi?ie, a oaeiae eaoaioii c eeiii/ieie
i?iyaaie a iiaeaeueoi ia?iiaee aeeooy.

Ia oei iioeo iioaeoeieieo caoai?thaaiue eaoaioia aa?iaoe/ia iioaeoeiy
iiaea aeoeaicoaaoeny. A oeueiio aeiaaeeo aeiaaiinoeea aa?iano, cia/ii
oneeaaeith?oueny, iniaeeai eiee inoaiiie ia?aaiaa? aac iioeiaeaeaiiy
oei?e oa neeciaeo iaieiiie. Iiae iioei, iiaeiaia iieno-iioaeoeiy ia?
oyaeei ianeiaeee oa cia/io eaoaeueiinoue. A aeinooiiie iai eioa?aoo?i ie
ia ciaeoee aiaeiiinoae a?aeiinii eeiiiei-eaai?aoi?ieo e?eoa?i?a
aeiaaiinoeee oa iiaeeeainoae ia?aaeaa/aiiy ia?aaiao aa?iaoe/ii?
iioaeoei? o aeioae ?aiiueiai aieo, ia oei aino?eo eeoeiaeo iioaeoeie
(AEI) oa aino?eo iioaeoeie aeeoaeueieo oeyoia (AIAeO).

Oei iicieiai/ii oi?ie aoee ia?aii iaie ia aeiaaeeiai, oiio ui c i?eaiaeo
oyaeeiai ia?aaiao AEI oa AIAeO aei iioaeoeieii? eiea?ii iio?aiey?
ia?aaaaeia eieueeinoue aeioae.

Ie cono?iee eeoa iaeeie/i? aeaii i?i iiaeeeainoi i?iaiicoaaiiy ia?aaiao
iioaeoeieieo caoai?thaaiue o aeioae, ia iiaenoaai canoinoaaiiy
eiii’thoa?iiai iiiioi?iiao.

Iiae iioei, caiaeii c ?a?iiaenueeith eiioeaioei?th AIIC «Caei?ia’y aeey
anio aei 2000 ?ieo», aea?aeaae iiaeiii iaoe aeieiai iaoaiicie, yei
iaiaoiaeii aeey iiiioi?iiao, ioeiiee oa ai?ioueae c iaaacia/ieie aeey
caei?ia’y /eiieeaie ioi/oth/iai na?aaeiaeua.

Ioaea, ?ic?iaea eeiiiei-eaai?aoi?ieo e?eoa?i?a aeiaaiinoeee aa?iaoe/ii?
iieno-iioaeoei? o aeioae ?aiiueiai aieo caea?oueny iai aeooaeueiith, ?
aeaa ciiao nai?/anii aeiaaiinooaaoe, ia?aaeaa/aoe ia?aaia oa ianeiaeee
caoai?thaaiiy, a oaeiae i?e iaiaoiaeionoi ai?iaaaeaeoaaoe niaoeeoi/io
oa?aiith.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoeiy ?
o?aaiaioii niieueii? ieaiiai? iaoeiai-aeineiaeii? ?iaioe eaoaae?e
aeeoy/eo iioaeoeieieo oai?ia Oa?eianueeiai iinoeoooo oaeineiiaeaiiy
eiea?ia oa Oa?eianueeiai IAeI iie?iaiieiai? oa iioiieiai? ii.
I.I.Ia/iieiaa OeO.4.33.99. «Ai?onieiai/iee iiiioi?iia ca aa?ianai?onaie
(HSV-1, HSV-2, CMV) i aea/aiiy ?o ?iei a ?icaeoeo iaoa?einueei-ieiaeiai?
iioaeoei?, caoai?thaaiiinoi aeioae iieiaeoiai aieo oa thiaeia, aeey
iiaeaeuaiiy yeinoi eieoaaeueii-aeiaaiinoe/iiai i?ioeano”.

Iaoa aeineiaeaeaiiy i caaea/i aeineiaeaeaiiy. Iaoa aeineiaeaeaiiy –
iieiioeoe aeiaaiinoeeo oa aecia/eoe i?iaiic aa?iaoe/ii? iieno-iioaeoei?
o aeioae ?aiiueiai aieo ia iiaenoaai aiaeico noeoiiinoi
eeiiiei-aiaiianoe/ieo oa eaai?aoi?ieo iciae.

Aeey aeinyaiaiiy iinoaaeaii? iaoe iaiaoiaeii ae?ioeoe oaei caaea/i:

– aea/eoe eeiiiei-eaai?aoi?ii iniaeeainoi ia?aaiao aa?iaoe/ii? iioaeoei?
ia oei AEI oa AIAeO o aeioae ?aiiueiai aieo;

– ie?aneeoe iaeaieueo iioi?iaoeaii eeiiiei-aiaiianoe/ii i eaai?aoi?ii
iciaee aeiaaiinoeee oa i?iaiicoaaiiy ia?aaiao aa?iaoe/ii? iioaeoei? ;

– aecia/eoe ee?i?ei-aeiaaiinoe/ia cia/aiiy ?ioiieia?/ieo ia?ea?ia
aa?iaoe/ii? iioaeoei?;

– ia iiaenoaai aiaeia?aieo ca nai?th iioi?iaoeaiinoth aiaiianoe/ieo oa
eeiiiei-eaai?aoi?ieo iciae neeanoe oano-ea?oo, yea a aeicaieeea
iie?aueoe aeni?an-ae?aaiinoeeo oa i?iaiic aa?iaoe/ii? iioaeoei?.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoaoia iieyaa? a oiio, ui aaoi?ii:

– anoaiiaeaia /anoioa ?io?eoaaiiy a??onii cae/aeiiai aa?iano ae?oae,
oai?eo ia oyaee? oi?ie aino?eo eeoeiaeo ?ioaeoe?e oa aino?eo ?ioaeoe?e
aeeoaeueieo oeyo?a;

– aeiaaaeaii, ui ?io?eoaaiiy a??onii cae/aeiiai aa?iano iaaaoeaii
aieeaa? ia ia?aa?a aino?eo eeoeiaeo ?ioaeoe?e oa aino?eo ?ioaeoe?e
aeeoaeueieo oeyo?a;

– ia i?aenoaa? ee?i?/ieo niinoa?aaeaiue, noaoenoe/iiai aiae?co
aiaiianoe/ieo oa ee?i?ei-eaai?aoi?ieo iieaciee?a ia?aa?ao oyaeeeo oi?i,
aea/a?ieo ?ioaeoe?eieo caoai?thaaiue o ae?oae, ?io?eiaaieo a??onii
cae/aeiiai aa?iano, ?ic?iaeaii oano-ea?oo aeni?an-ae?aaiinoeee oa
i?iaiico aa?iaoe/ii? ?ioaeoe??.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoaoia. Aeei?enoaiiy
aeiaaiinoe/ii-i?iaiinoe/ii? oano-ea?oe aea? ciiao anoaiiaethaaoe
nai?/anii aeiaaiic aa?iaoe/ii? iioaeoei? o aeioae ?aiiueiai aieo oa
?aoeiiiaeueii aeei?enoiaoaaoe ao?io?iiio i?ioeai?onio oa?aiith, ui
iiceoeaii aieeaa? ia ia?aaia oa ianeiaeee caoai?thaaiiy.

Oano-ea?oa, ia iiaenoaai yei? iieiioo?oueny aeiaaiinoeea, eieoaaiiy oa
i?iaiic i?e aa?iaoe/iie iioaeoei? o aeioae, iiaea aooe aeei?enoaia a
aoaeue-yeeo eieoaaeueieo caeeaaeao, a oiio /enei a
aiaoeaoi?ii-iieieeiii/ieo oiiaao.

Iaoa?iaee aeena?oaoei? aeei?enoiaothoueny a eaeoeiyo ? i?aeoe/ieo
caiyooyo eaoaae?e aeeoy/eo ?ioaeoe?eieo oai?ia Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo oa oeeeeia oaeineiiaeaiiy eiea?ia c
aeeoy/eo iioaeoeieieo oai?ia Oa?eianueeiai iinoeoooo oaeineiiaeaiiy
eiea?ia. Ca iaoa?iaeaie aeena?oaoei? ?ic?iaeaia
aeiaaiinoe/ii-i?iaiinoe/ia oano-ea?oa oa iioaeieiaaii iaoiaee/ii
?ic?iaee, yei aeei?enoiaothoueny o ?iaioi Oa?eianueei? iaeanii? aeeoy/i?
iioaeoeieii? eeiii/ii? eiea?ii oa aeeoy/i? eiea?ii ? 5 i.Oa?eiaa,
?aeiiieo iieieeiiieao ? 15, 7, 23.

Iniaenoee aianie caeiaoaa/a. Aaoi? naiino?eii ee?i?/ii niinoa??aaea
oai?eo. A?aea aaciina?aaeith o/anoue o noai?aii? i?ea?iaeueii?
eiii’thoa?ii? aace aeaieo. Cae?enieea noaoenoe/io ia?iaeo ?acoeueoao?a,
iaa?oiooaaea iniiai? iieiaeaiiy oa aeniiaee ?iaioe. I?aeaiooaaea aei
ae?oeo iaoiaee/io ?ic?iaeo, i?ea?iaeuei? noaoo?, ioi?ieea aeena?oaoe?eio
?iaioo oa aaoi?aoa?ao.

Eaai?aoi?ii aeineiaeaeaiiy aoee i?iaaaeaii niieueii c oaoiaoeyie
naiioa?ii-aiiaeaiiieiai/ii? noaioei? Iiaaeaiii? caeicieoei (e.i.i.
I.A.Ei?iaeiaa) oa ai?onieiai/ii? eaai?aoi?i? IAeIEE i.Oa?eiaa
(I.I.Cicoey), i?e ni?eyiii caa. aiaeaeieaiiyi IAeIEE i.Oa?eiaa
A.I.?eaaeei.

Ai?iaaoeiy ?acoeueoaoia aeena?oaoei?. Iniiaii iieiaeaiiy ?iaioe aoee
aeeeaaeaii oa iaaiai?ai? ia 2 iaoeiiiaeueiiio eiia?ani aianoaciieiaia
Oe?a?ie (1996), Ana?inienueeie iaoeiaie eiioa?aioei? i?enay/aiie
aeooaeueiei ieoaiiyi no/anii? iaaeiao?i? i.Na?aoia (1997), Ieaioii
Anioeiaoei? iioaeoeiiiinoia Oe?a?ie (1998), ia V c’?caei iioaeoeiiiinoia
Oe?a?ie (i.Oa?iiiieue, 1998), iaoeiai-i?aeoe/ieo eiioa?aioeiyo iaeanoii?
aeeoy/i? iioaeoeieii? eeiii/ii? eiea?ii (Oa?eia, 1997, 1998), can?aeaii?
anioe?aoe?? aeeoy/eo e?ea??a (Oa?eia, 1997, 1998), ni?eueiiio can?aeaii?
eaoaae? aeeoy/eo ?ioaeoe?eieo oai?ia, ai?aeai?ieia?? oa iaaee/ii?
ia?aceoieia??, aeeoy/i? aianoac?ieia?? oa ?ioaineaii? oa?ai??,
?ioaeoe?eieo oai?ia O?OE ? aeeoy/eo ?ioaeoe?eieo oai?ia Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoa.

Ioaeieaoei?. Ca iaoa?iaeaie aeena?oaoei? iioaeieiaaii iaeia iaoiaee/ia
?ic?iaea oa 14 ?iaio, c yeeo 3 o aeaeaiiyo, ui ?aeiiaiaeiaaii AAE
Oe?a?ie.

Ianya oa no?oeoo?a aeena?oaoei?. Aeena?oaoeiy aeeeaaeaia ia 1 2 1
noi?iieao ae?oeiaaiiai oaenoo oa neeaaea?oueny ic anooio, iaeyaeo
eioa?aoo?e, 4 ?icaeieia aeanieo aeineiaeaeaiue, iaaiai?aiiy iaea?aeaieo
?acoeueoaoia, aeniiaeia, i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo eioa?aoo?e,
yeee iinoeoue 170 e?oa?aoo?ieo aeaea?ae.

?iaioa iethno?iaaia 25 oaaeeoeyie oa 1 ?enoieii.

INIIAIEE CIINO ?IAIOE

O anooii iaa?oioiao?oueny aeai? i aeooaeueiinoue oaie aeineiaeaeaiiy,
aecia/athoueny iaoa aeineiaeaeaiue, iaoiaeeea aeineiaeaeaiue, iaoeiaa
iiaecia, i?aeoe/ia cia/aiiy ?iaioe.

O ia?oiio ?icaeiei ?icaeyaeathoueny iniaeeainoi eeiiiee aa?iaoe/ii?
iioaeoei? o aeioae, iiaeeeainoi aeiaaiinoeee oa ia?aaeaa/aiiy ??
ia?aaiao c aeei?enoaiiyi aeiaaiinoe/ii-i?iaiinoe/ieo aeai?eoiia.
Iieacaii, ui iniaeeai o?oaeiiui i?e aeiaaiinoeoei aa?iaoe/ii? iioaeoei?
aeieeathoue eiee aiia ia?aaiaa? aac iioeiaeaeaiiy oei?e oa neeciaeo
iaieiiie ia oei iioeo iioaeoeieieo caoai?thaaiue.

Iaeiei ic cania?a iieiioaiiy aeiaaiinoeee oa ia?aaeaa/aiiy ia?aaiao
aa?iaoe/ii? iieno-iioaeoei? o aeioae ?aiiueiai aieo ? ?aoaeueiee aiaeic
i?eoaiaiieo aeey ia? aiaiianoe/ieo oa eeiiiei-eaai?aoi?ieo iciae ca
aeiiiiiaith eiii’thoa?iiai iiiioi?iiao.

A ae?oaiio ?icaeiei iaaiai?ththoueny iaoa?iaee oa iaoiaee
aeineiaeaeaiiy. Aoei ianoaaeaii 147 aeioae o aioei aiae 1 iinyoey aei 3
?ieia, yei ia?aaoaaee ia eieoaaiii a Iaeaniie aeeoy/ie iioaeoeieiie
eeiii/iie eiea?ii i.Oa?eiaa c i?eaiaeo aino?eo eeoeiaeo ?ioaeoe?e oa
aino?eo iioaeoeieieo aeeoaeueieo oeyo?a. Na?aae ianoaaeaieo oeii/eeia
aoei 83 (56,5%), aeia/aoie – 64 (43,5%). Ca aieii ia?aaaaeaee aeioe
ia?oeo o?ueio iinyoeia aeeooy – 61 (41,4%). O anio aeioae iaa iinoea
oyaeeee ia?aaia oai?iae, ui iio?aaoaaei eieoaaiiy a ?aaiiiaoeieiiio
aiaeaeieaiii. Caaaeueiii?eeiyoi aeineiaeaeaiiy aeicaieeee anoaiiaeoe
aaeoa?iaeueio aai ai?onio aoiieiaith caoai?thaaiiy o 73,5% aeioae o
?aooe aeioae 26,5% aeiaaiic caeeoeany aoiieiai/ii ia aa?ioieiaaiei
(oaae.1).

Oaaeeoey 1 – ?iciiaeie aeioae ?aiiueiai aieo ii iicieiai/iei oi?iai
caoai?thaaiiy

Aeiaaiic Eieueeinoue oai?eo

aan. %

Naeueiiiaeueic 56 38,1%

Oeaaeueic 10 6,8%

Aoa?ioiic 2 1,4%

AEI iaoiiaeaii OIO 21 14,3%

Iaaecia/aii AEI 27 18,3%

A?iioio 14 9,5%

Iiaaiiii? 17 11,6%

?acii 147 100%

Caiaeii c iaoith aeineiaeaeaiiy, ani aeioe ianoaaeaii ia ia?ea?e
aa?iaoe/ii? iioaeoei? c aeei?enoaiiyi:

1) aeey ciaoiaeaeaiiy a e?ia? oai?eo ai?ona cae/aeiiai aa?iana 1 oa 2
oeio (ACA-1 oa ACA-2) – iioiioa?iaioii? oano-nenoaie «Aa?ian Ne?ei», yea
ae?iaey?oueny NI «IEA?IAAeEE» (?iniy).

2) aeey aeyaeaiiy niaoeeoi/ieo aioeoie aei ACA-iioiioa?iaioii?
oano-nenoaie, ?ic?iaeaiie Iaeanueeei iiaei?e?inoaii ii ae?iaieoeoao
aaeoa?ieieo i?aia?aoia.

3) aeey aeyaeaiiy iecueeiaaiaeieo iioiiaeiaoeiiia G aei
ACA-iioiioa?iaioii? oano-nenoaie («Aa?ian-aeiaaiino», ?iniy, Iineaa).

?acii c niaoeeoi/ieie aeineiaeaeaiiyie ia ia?ea?e aa?iaoe/ii? iioaeoei?
aea/aee iieacieee ia?ioa?ieii? e?iai, i?ioaiiia?aie, eii?ia?aie. Oai?ei,
o yeeo aoee eeiii/ii iciaee o?aaeaiiy aioo?ioiio i?aaiia, i?iaiaeeee
oeueo?icaoeiaa aeineiaeaeaiiy ia aiia?aoi «Neaia? OE-628-A». Ca
aeiiiiiaith iae?iniiia?aoi? ioeiithaaee noai oeoii/eiai? nenoaie, noaeei
oa aoiuieueiinoi ?a/iaei aieiaiiai iiceo.

Iaea?aeaii ?acoeueoaoe noaoenoe/ii ia?iaeaii ia IAI-?N-486DX-100
(i?ia?aiia caaania/aiiy «Statgraphics»), c aeei?enoaiiyi i?eeiyoeo
iaoiaeia aa?iaoeieii? noaoenoeee. Noaoenoe/ii cia/eieie aaaaeaee aeaii c
?iaiai ai?iaiaeiinoi ?<0,05. Aeiaaiinoe/ii eiaoioei?ioe ia/enethaaee ca oi?ioeith Aae?na, iioi?iaoeaiinoue oaeoi?ia ca oi?ioeith Eoeueaaea, ii?iaiai noie aeiaaiinoe/ieo eiaoioei?ioia ca oi?ioeith Aaeueaea. A o?aoueiio ?icaeiei iiaeaia eeiii/ia oa?aeoa?enoeea oai?eo ia aa?iaoe/io iieno-iioaeoeith aeioae ?aiiueiai aieo. Ia ia?ea?e aa?iaoe/ii? iioaeoei? aoei ianoaaeaiii 147 oai?eo aeioae, c yeeo 107 (72,8%) aeyaeeenue iioieiaaieie, iioi 40 aeioae aoee iaiioieiaaieie. Iaeaeai a?oie aeioae aoee ?ai?acaioaoeaii ca aieii, noaoaaith iaeaaeiinoth oa iicieiai/ieie oi?iaie caoai?thaaiiy. Oea aeicaieeei i?iaiaeicoaaoe aiaiianoe/ii oaeoi?e o aeioae iaio a?oi, aeayei c yeeo, ca aeaiieie eioa?aoo?e iiaeooue ci?eyoe iioieoaaiith aeeoeie ACA oa aieeiooe ia ?icaeoie oa iiaeaeueoee ia?aaia o ieo aa?iaoe/ii? iioaeoei? (oaae. 2). Oaaeeoey 2 – Aiaiianoe/ii oaeoi?e ?eceeo ?icaeoeo aa?iaoe/iii iioaeoei? o aeioae N i/i Oaeoi?e ?eceeo ?icaeoeo aa?iaoe/ii? ?ioaeoe?? Aaee ? iioieiaaii (n=107) iaiioieiaaii (n=40) 1 2 3 4 5 1. Niaaeeiainoue o aiaeiioaiii aa?ianai?onii? iioaeoei? 1,7±0,054 1,52±0,107 p<0,001 2. Iayaiinoue ?aoeeaeeaoth/aai aaiioaeueiiai aai eaaiaeueiiai aa?iana o aaoueeia 1,64±0,051 1,4±0,076 ?<0,001 3. Oneeaaeiaiee ia?aaia aaaioiinoi 1,71±0,043 1,57±0,035 ?<0,001 4. Ia?aae/anii iieiae 1,15±0,035 1,15±0,061 ?>0,05

5. Iecueea iana oiea i?e ia?iaeaeaiii (iaiueoa iiae 2500 a.) 1,13±0,033
1,13±0,061 ?>0,05

6. Oneeaaeiaiee ia?aaia ?aiiueiai ia?eiaoaeueiiai ia?iiaeo (aiiio?ioiy,
aeiaoac, caoyaeia «oiceieiai/ia aeiaoyieoey», aiaenoaaaiiy o II?,
o?eaaeee noaoaa?eeioao) 1,59±0,047 1,45±0,079 ?<0,001 7. Iayaiinoue iaa?ieiai/ii? neiioiiaoeee (ia?eiaoaeueia aioeaoaeiiaoiy, iayaiinoue noaeii, aiii- oa aiia?oiion i'ycia, AeOeI, aeiaaeee ao?aoe naiaeiiinoi oa iio.) 1,51±0,048 1,4±0,078 ?<0,001 8. *anoi "canooaeii caoai?thaaiiy" 1,89±0,071 1,8±0,013 ?<0,001 I?iaeiaaeaiiy oaae.2. 1 2 3 4 5 9. Iayaiinoue a aiaiiaci o?iii/ieo caoai?thaaiue aeeoaeueieo oeyoia oa ei?-i?aaiia (oiiceeio, oa?eiaio, aaeii?io, ioio, ea?eiaio, a?iioio, iiaaiiiiy) 1,63±0,067 1,6±0,01 ?<0,001 10. Iayaiinoue a aiaiiaci caoai?thaaiiy i/ae (eii'thieoeaio, ea?aoieii'thieoeaio, aeaoa?io) 1,29±0,05 1,27±0,079 ?<0,001 11. Iayaiinoue noiiaoeoia 1,38±0,055 1,37±0,011 ?<0,001 12. Niinoa?iaaany /e eiee-iaaoaeue aa?iaoe/iee aenei o oai?eo ia oei iioiai caoai?thaaiiy 1,02±0,016 1,0±0 ?<0,001 13. Ciiie ?icii?ia aeei/eiai? caeice 1,24±0,041 1,15±0,057 ?<0,001 Aiaeic 13, aiaeia?aieo ca iioi?iaoeaiinoth aiaiianoe/ieo oaeoi?ia ?eceeo ?icaeoeo aa?iaoe/ii? iioaeoei? o aeioae ?aiiueiai aieo, aeiaia, ui iaoieiai/ii iieiae oa iana oiea i?e ia?iaeaeaiii iaeiaeiai /anoi niinoa?iaaeenue a iaio a?oiao aeioae oa aeyaeeenue ia iioi?iaoeaieie. Iioi 11 oaeoi?ia c aenieith aeinoiai?iinoth /anoioa niinoa?iaaeenue o iioieiaaieo ACA aeioae. Aoee aea/aii iniaeeainoi eeiii/iiai ia?aaiao aa?iaoe/ii? iioaeoei? o aeioae ia oei AEI oa AIAeO. Ianoaaeaii 147 aeioae aoee iiaeieaii ia aeai a?oie, caeaaeio aiae aeiaaiico c yeei aiie ainiioaeicoaaeeny o eeiiieo. Ia?oo a?oio neeaee 116 (78,9%) aeioae, oai?eo ia AEI, ae?oao – 31 (21,1%) aeeoeia, oai?a ia AIAeO. A naith /a?ao 116 aeioae c AEI oaae aoee iiaeieaii ia aeai a?oie, caeaaeii aiae iayaiinoi ia?ea?ia aa?iaoe/ii? iioaeoei?: 85 aeioae (73,3%) , yei iaee ia?ea?e aa?iaoe/ii? iioaeoei?, neeaee iniiaio a?oio; 31 (26,7%) aeeoeia c iaaaoeaieie ?acoeueoaoaie ia ia?ea?e ACA – eiio?ieueio. Caeaaeii aiae iayaiinoi ia?ea?ia aa?iaoe/ii? iioaeoei? 31 aeeoeia c AIAeO oaae aoee ?icaeieaii ia aeai a?oie: 22 (71%) aeeoeie neeaee iniiaio a?oio, 9 (29%) – eiio?ieueio. Aea/aiiy ia?aaiao aa?iaoe/ii? iioaeoei? o aeioae, ia oei AEI oa AIAeO, aeicaieeei aeyaeoe neiaeoth/i i?eoaiaiii aeey oei?? oai?iae caaaeueii iniaeeainoi: ii-ia?oa, oai?iaa, c yeith aeeoeia ia?aaoaa? o eiea?ii, ia oei aeoeaaoei? aa?iaoe/ii? iioaeoei?, iaaoaa? caoyaeiiai ia?aaiao; ii-ae?oaa, o oai?iai c i?eno-?ioaeoe??th a ia?o? aei? caoai?thaaiiy, ?a?no?o?oueny caieueoaiiy ia/iiee oa naeaciiee; ii-o?ao?, a e?iai ?io?eiaaieo, iniaeeai ia ii/aoeo oai?iae, niinoa?iaathoueny oa noaoenoe/ii ai?iaiaeii aeiaoa ?a?no?othoueny aiaiiy, o?iiaioeeoiiaiiy, aiiii?ioa?iaiiy oa aiiiaaiiaaeiaoeiiaiiy. Ie?aneaii eeiiiei-eaai?aoi?ii iciaee ?acii c aeuacacia/aieie aiaiianoe/ieie oaeoi?aie ?eceeo, aacoiiaii, ia iiaeia aaaaeaoe niaoeeoi/ieie i i?eoaiaiieie oieueee aeey aa?iaoe/ii? iioaeoei?, aea ?o iayaiinoue aea? iiaenoaao aeey ianoaaeaiiy oai?iai ia ia?ea?e aa?iaoe/ii? iioaeoei?. A /aoaa?oiio ?icaeiei aoee aea/aii iniaeeainoi niaoeeoi/ii? aeiaaiinoeee aa?iaoe/ii? iioaeoei? o aeioae ?aiiueiai aieo. Ia?ea?e aa?iaoe/ii? iioaeoei? aoee aeyaeaii o 107 (72,8% aeiaaeeia) c 147 aeioae ?aiiueiai aieo, ui ? aeoaea aenieei ?iaiai iioieoaaiiy. Aino?ee ia?aaia aa?iaoe/ii? iieno-iioaeoei? iaee 49 aeioae (45,8% aeiaaeeia), iiii-iioaeoei? 14 (13,1%) aeioae. O iioeo 44 aeioae (41,1% aeiaaeeia) iioaeoeiy aoea eaoaioiith. I?e ianoaaeaiii oai?eo ia ia?ea?e aa?iaoe/ii? iioaeoei? iaie aoee aeyaeaii neiaeoth/i iniaeeainoi niaoeeoi/ii? aeiaaiinoeee oei?? oai?iae: 1. O aeioae ?aiiueiai aieo i?e iayaiinoi aioeaaio ACA a e?iai, aioeoiea aei iueiai o ne?iaaooei iiaeooue aooe aiaenooii, aai ciaoiaeeoenue o oeo?ao ieae/a, iiae aeiaaiinoe/ii. Caiaeii c iaoeie aeaieie, oea niinoa?iaaeinue o 34 (68,0±6,6%) c 50 aeioae ?aiiueiai aieo. Oiio i?e ianoaaeaiii aeioae ?aiiueiai aieo ia ia?ea?e aa?iaoe/ii? iioaeoei? aeioeieueiioa aeei?enoiaoaaoe aeey aeiaaiinoeee iaoiae IOA, yeee aeicaiey? aeyaeoe aioeaai ACA a e?iai. 2. I?e aiaenooiinoi aioeaaio ACA a e?iai, ui iiaea aooe iaoiiaeaii ei?ioei/aniith ai?onaii?th, neiae aeei?enoiaoaaoe aeey aeiaaiinoeee iaoiae IOA, yeee aeicaiey? aeyaeoe iecueeiaaiaeii aioeoiea aei ACA. Canoinoaaiiy iaoiaeo iecueeiaaiaeieo aioeoie aeicaieeei iai o 13 c 40 aeioae ?aiiueiai aieo (32,5±7,4% aeiaaeeia), o ne?iaaooei e?iai yeeo aioeaai ACA ciaeaeaii ia aoei, aeiaaiinooaaoe aino?o aa?iaoe/io iioaeoeith. A i'yoiio ?icaeiei ia iiaenoaai canoinoaaiiy eiii'thoa?iiai iiiioi?iiao, ?aoaeueii aoee ?ic?iaeaii 107 inoi?ie oai?ia aeioae ?aiiueiai aieo c aa?iaoe/iith iioaeoei?th oa 40 inoi?ie oai?ia aeioae o yeeo ia?ea?e aa?iaoe/ii? iioaeoei? aeyaeaii ia aoee. I?iaaaeaiee noaoenoe/iee aiaeic aeicaieea a?ae?a?aoe c 35 cia?oo ocyoeo oaeoi??a 18 iaeaieueo iioi?iaoeaieo iciae (?en.1.) aeey i?iaiicoaaiiy ia?aaiao aa?iaoe/ii? iioaeoei? oa ?ic?iaeoe oano-ea?oo aeey aeiaaiinoeee oa ia?aaeaa/aiiy ia?aaiao aa?iaoe/ii? iioaeoei? o aeioae ?aiiueiai aieo (oaae.3). ?en.1. – Aeiaiacii iioi?iaoeaiinoi oaeoi?ia, aiaeia?aieo aeey aeiaaiinoeee iiii- oa i?eno-aa?iaoe/ii? ?ioaeoe??. I?ei?oea: ? – ?ioi?iaoeai?noue; F – aea/a?iee oaeoi?. Ia iiaenoaai io?eiaieo aeiaaiinoe/ieo eiaoioeiaioia ae?aoiaothoue ?o caaaeueio noio. sseui noia ae?aaiinoe/ieo eiao?oe??io?a ? iiceoeaiith aaee/eiith – ae?aaiinoothoue aa?iaoe/io ?ioaeoe?th, eiee iaaaoeaiith – ae?aaiic a?aeoeeythoue. Aeey i?eeiyooy ??oaiiy i iayaiino? aai a?aenooiino? o oai?iai aa?iaoe/ii? ?ioaeoe??, c iaaiei ??aiai iaae?eiino?, aoee ia/eneai? ii?iaia? noie ae?aaiinoe/ieo eiao?oe??io?a (oaae.4), a?aeiia?aeii ??aith iiieeee, ae?aaeaiiio o a?aenioeao. Iai?eeeaae, io?eiaia noia ae?aaiinoe/ieo eiao?oe??io?a aei??aith? 91. Iaeaeeua aei iueiai /enei o oaaeeoe? 4 – 91,7. Iiieeea ? o oeueiio aeiaaeeo neeaaea? 10%, ? – a?aeiia?aeii 1%, ?acii oea 11%. sseui ca caaaeueio ?iia??i?noue ?icaeoeo aa?iaoe/ii? ?ioaeoe?? i?eeiyoe 100%, oi 100%–11%=89% neeaaea? ?iia??i?noue ae?aaiico aa?iaoe/ii? ?ioaeoe?? o iaoiio aeiaaeeo, iiaeeeaa iiieeea aei??aith? eeoa 11%. Oaaeeoey 3 – Aeiaaiinoe/ii-i?iaiinoe/ia oano-ea?oa Oaeoi?e ?eceeo ?icaeoeo aa?iaoe/ii? ?ioaeoe?? (F) Ioeiiea ae?aciino? oaeoi?a o aaeao Ae?aaiinoe/i? eiao?oe??ioe 1 2 3 F-1 Niaaeeiainoue o aiaeiioaiii aa?ianai?onii? iioaeoei? - iiooi c iaeaeeaeueo ?iaeieo ia oai?i? ia o?iii/io ?aoeeaeeaoth/o aa?iaoe/io iioaeoeith; 1 -6,75 - oai?i? ia aa?iaoe/io iioaeoeith iaeei c ?iaeieo; 2 6,77 - oai?ithoue ia aa?iaoe/io iioaeoeith aeaa oa aieueoa ?iaeieo 3 -5,1 F-2 Iayaiinoue aaiioaeueiiai aa?iana o aaoueeia: - ia niinoa?iaaany; 1 -4,57 - niinoa?iaaany aa?iaoe/iee aenei ia noaoaaeo i?aaiao o aaoueeia; 2 3,71 - aeiaai ia caaithaaiia ae?acea oieee iaoee o iaoa?i 3 0 F-3 Ia?aaia aaaioiinoi: - aac iniaeeainoae; 1 -4,05 - ciaoiaeaeaiiy o eiea?ii c i?eaiaeo c?eao aaaioiinoi oa iioeo oneeaaeiaiue 2 2,3 F-4 Ia?aaia ?aiiueiai ia?eiaoaeueiiai ia?iiaeo: - aac oneeaaeiaiue; 1 -2,9 - c oneeaaeiaiiyie (aiiio?ioiy, aeiaoac, caoyaeia "oiceieiai/ia aeiaoyieoey", aiaenoaaaiiy o II?, o?eaaeee noaoaa?eeioao) 2 2,5 F-5 Iayaiinoue iaa?ieiai/ii? neiioiiaoeee: - ia niinoa??aa?oueny; 1 -2,0 - niinoa?iaa?oueny (aiiio?ioiy, ia?eiaoaeueia aioeaoaeiiaoiy, iayaiinoue noaeii, aiii- oa aiia?oiion i'ycia, AeOeI, aeiaaeee ao?aoe naiaeiiinoi oa iio.) 2 2,2 F-6 *anoioa "canooaeieo caoai?thaaiue": - ia aieueoa iiae iaeei ?ac ia ?ie; 1 -3,4 - 2-3 ?ace ia ?ie; 2 4,0 - /anoioa iiae 4-5 ?acia ia ?ie 3 -1,7 F-7 Iayaiinoue o?iii/ieo caoai?thaaiue aeeoaeueieo oeyoia oa ei?-i?aaiia (oiiceeio, oa?eiaio, aaeii?io, ioio, ea?eiaio, a?iioio, iiaaiiiiy): - ia niinoa?iaathoueny; 1 0,4 - ?a?no?othoueny caaino?aiiy 1-2 ?ace ia ?ie; 2 -1,69 - caaino?aiiy oai?iae ?a?no?o?oueny /anoioa iiae 2 ?ace ia ?ie 3 5,3 I?iaeiaaeaiiy oaae.3. 1 2 3 F-8 Iayaiinoue noiiaoeoia: - ia niinoa?iaaeeny; 1 -0,87 - iaee iinoea ia /anoioa iiae 1 ?ac ia ?ie; 2 4,98 - niinoa?iaathoueny /anoi 3 1,8 F-9 Ciiie ?icii?ia iiaea?oaeeiii? caeice: - ia ?a?no?oaaeeny; 1 -1,25 - caieueoaiiy aeei/eiai? caeice 2 4,7 F-10 ?icii?e ia/iiee: - ia caieueoaia 1 -18,24 - caieueoaia 2 8,77 F-11 ?icii?e naeaciiee: - ia caieueoaia 1 -6,93 - caieueoaia 2 20,24 F-12 Aiaiiy (eieueeinoue a?eo?ioeeoia o ia?ioa?ieiie e?iai oa ?iaaiue aaiiaeiaiio) - ii?ia 1 -12,28 - cieaeaia 2 14,84 F-13 Eieueeinoue o?iiaioeeoia o ia?ioa?ieiie e?iai: - ii?ia; 1 -6,04 - o?iiaioeeoiiaiiy 2 29,12 F-14 ?iaaiue caaaeueiiai aieea a e?iai - ii?ia; 1 -18,41 - cieaeai 2 16,21 F-15 ?iaaiue aaiaaeiaoeiiia o ia?ioa?ieiie e?iai - ii?ia; 1 -8,88 - cieaeai 2 18,71 F-16 Aeaii aoiaioeaoaeineiii?: - ii?iioaiciy; 1 -1,47 - aiia?oaiciy 2 12,2 F-17 Iayaiinoue aioeaaio ACA o e?iai: - aioeaai ia ciaeaeaii; 1 -8,2 - ciaeaeaii aioeaai o iecueeie eiioeaio?aoei?; 2 0 - ciaeaeaii aioeaai o aenieie eiioeaio?aoei? 3 0 F-18 Iayaiinoue aioeoie aei ACA o ne?iaaooei e?iai: - aioeoie ia ia?; 1 -19,0 - oeo?e aioeoie 1:32 – 1:128; 2 25,9 - oeo?e aioeoie aeua iiae 1:128 3 0 I?e ae?aaiinoe/iiio eiao?oe??io? c iaaaoeaiei ciaeii – 91%, iaaiaee, c ?iia??i?noth 89% ae?aaiic aa?iaoe/ii? ?ioaeoe?? iiaeii a?aeoeeeoe c iiieeeith a 11%. Oaaeeoey 4 – Ii?iaia? noie aeiaaiinoe/ieo eiaoioei?ioia 0% 1% 2% 3% 4% 5% 6% 7% 8% 9% 0% 199,5635 169,0196 150,965 138,0211 127,8754 119,4977 112,3385 106,0698 100,4799 10% 95,42425 90,79973 86,53014 82,55759 78,83704 75,33277 72,01593 68,86292 65,85413 62,97314 20% 60,206 55,74078 54,96719 52,47692 50,06024 47,71213 45,42584 43,19591 41,01745 38,88604 30% 36,79768 34,74874 32,73589 30,75609 28,8065 26,88453 24,98775 23,11388 21,26081 19,42652 40% 17,60913 15,80682 14,01787 12,24064 10,47354 8,71502 6,96359 5,2178 3,47621 1,73741 I?ei?oea: ? oa ? – iiieeee a ae?aaiinoeoe? caoai?thaaiiy. Iioi?iaoeaiinoue ?ic?iaeaii? iaie i?iaiinoe/ii-aeiaaiinoe/ii? oano-ea?oe aeyaeeany aenieith. O aeioae iniiaii? a?oie, ui iaee ia?ea?e aa?iaoe/ii? iioaeoei?, io?eiaii ?acoeueoaoe a na?aaeiueiio o 92% aeiaaeeia aeaaaee ciiao aeiaaiinooaaoe aa?iaoe/io iioaeoeith oa naiae/eee ia ei?enoue iani?eyoeeaiai ia?aaiao oai?iae o iaeaooiueiio. Iiieeea a oeie a?oii neeaea oieueee 8%. Aaaaeath/e ia oa, ui ia a eiaeiiio iaaee/iiio caeeaaei ? iiaeeeainoue ianoaaeeoe aeeoeio ia ia?ea?e aa?iaoe/ii? iioaeoei?, c oano-ea?oe aoee onoiooi oaeoi?e: (F-17) – iayaiinoue aioeaaio ACA oa (F-18) – iayaiinoue aioeoie aei ACA. Ea?oee onio 107 aeioae aoee ciiao ia?aei/aii. Iioi?iaoeaiinoue ea?oe a oeueiio aeiaaeeo aeaeieueea cieceeanue i neeaea a na?aaeiueiio 68% ia ei?enoue aeiaaiico aa?iaoe/ii? iioaeoei?, a iiieeea neeaea eeoa 32%. O aeioae, neeaaoeo eiio?ieueio a?oio, aoee io?eiaii neiaeoth/i ?acoeueoaoe: a na?aaeiueiio iiaeeeainoue aeieeiaiiy aa?iaoe/ii? iioaeoei? neeaea 7%, i?ioe ?icaeoeo oei?? oai?iae naiae/eee 93%. Iiney oiai, ye c ea?oe aoee onoiooi oaeoi?e (F-17) oa (F-18), ie io?eiaee a eiio?ieueiie a?oii aeioae neiaeoth/i ?acoeueoaoe: 64% naiae/eee i?ioe aeiaaiico aa?iaoe/ii? iioaeoei?, ia iiaeeeainoue ?icaeoeo aa?iano a oeie a?oii aeacoaaee 36%. AENIIAEE 1. O oai?eo, ui aini?oae?cothoueny c i?eaiaeo oyaeeeo oi?i aino?eo eeoeiaeo ?ioaeoe?e oa aino?eo iioaeoeie aeeoaeueieo oeyo?a, iioieiaaiinoue a??onii cae/aeiiai aa?iano neeaaea? 72,8%. Na?aae ieo o 13,1% aeyaeaia aino?a aa?iaoe/ia iiii-iioaeoeiy, 45,8% – aino?a aa?iaoe/ia iieno-iioaeoeiy, 41,1% – eaoaioia aa?iaoe/ia iieno-iioaeoeiy. 2. Iioieoaaiiy a??onii cae/aeiiai aa?iano aeioae ?aiiueiai aieo iaaaoeaii aieeaa? ia ia?aaia iioeo iioaeoeieieo caoai?thaaiue, ui iicia/a?oueny caieueoaiiyi o?eaaeinoi oa ae?aciinoi iniiaieo eeiiiei-eaai?aoi?ieo iieacieeia, a oaeiae iioyaeaiiyi i?iaiico oai?iae. 3. C iaoith iiaeaeuaiiy iioi?iaoeaiinoi eaai?aoi?ii? aeiaaiinoeee oa ioeiiee aeoeaiinoi e ia?aaiao aa?iaoe/ii? iioaeoei?, iaiao?aeii a ne?iaaooei e?iai iaeii/anii aecia/eoe aioeaai a??ono cae/aeiiai aa?iano oa iecueeiaaiaeii aioeoiea aei iueiai. 4. Aa?iaoe/ia iioaeoeiy o aeioae ?aiiueiai aieo, iniaeeai o ?aci ia?aaiao ia oei iioi? iioaeoeieii? iaoieiai?, ia ia? iaoaeia?/ieo eeiii/ieo iciae, ui cia/ii oneeaaeith? ?? aeiaaiinoeeo oa iaa?oioiaaiiy ?aoeiiiaeueii? oa?aii?. 5. Ia i?aenoaa? ee?i?/i?o niinoa?aaeaiue oa ee?i?ei-eaai?aoi?ieo iieacieeia ia?aaiao oyaeeeo oi?i aea/a?ieo iioaeoeieieo caoai?thaaiue o aeioae, iioieiaaieo a??onii cae/aeiiai aa?iano, ?ic?iaeaii oano-ea?oo, i?aeoe/ia canoinoaaiiy yei? iie?auo? aeni?an-aeiaaiinoeeo oa i?iaiic aa?iaoe/ii? iioaeoei?. 6. ?ic?iaeaia iaie aeiaaiinoe/ii-i?iaiinoe/ia oano-ea?oa eaaea o aeei?enoaiii, a ?? ai?iaaaeaeaiiy o ?iaioo aeeoy/eo noaoeiiia?ia oa iieieeiiie ia iio?aao? aeiaeaoeiaeo iaoa?iaeueieo aeo?ao. I?AEOE*II ?AEIIAIAeAOeI? 1. A?aoiaoth/e o?oaeiiui eeiii/ii? aeiaaiinoeee aa?iaoe/ii? iioaeoei? o aeioae, iniaeeai ia oei iioi? iioaeoeieii? iaoieiai?, i?iiiio?oueny aeei?enoiaoaaoe niaoeiaeueii ?ic?iaeaio aaoi?ii oano-ea?oo iaaeieieo e?eoa?i?a aeni?an-aeiaaiinoeee oa i?iaiico aa?iaoe/ii? iioaeoei? o aeioae ?aiiueiai aieo. 2. Caiaeii oano-ea?oe o oai?iai aecia/athoue oaeoi?e ?eceeo aa?iaoe/ii? iioaeoei? oa nooiaiue ?o ae?aciinoi a aaeao, yei iioii ciiiththoueny ia aiaeiiaiaeii eiaoioei?ioe. Caaaeueia noia eiaoioei?ioia iiaea aooe iiceoeaiith aai iaaaoeaiith, ui aiaeiiaiaeii icia/a? aenieee aai iecueeee nooiaiue ?eceeo aa?iaoe/ii? iioaeoei? o oai?iai. Aiaenioeiaee ae?ac oeueiai iieacieea ciaoiaeyoue a oaaeeoei ?iciiaeieo iiiai?iinoi aeiaaiinoe/ieo eiaoioei?ioia. 3. sseui i?e ia?aeiiiio eeiii/iiio ianoaaeaiii oyaeei oai?i? ia iioaeoeieio iaoieiaith aeeoeie aiaenioie noie aeiaaiinoe/ieo eiaoioei?ioia aoaea aeecueei 60%, oi a oaeiio aeiaaeeo iaeaaeeoue aeei?enoiaoaaoe niaoeeoi/io eaai?aoi?io aeiaaiinoeeo aa?iaoe/ii? iioaeoei?. 4. Aeey niaoeeoi/ii? aeiaaiinoeee aa?iaoe/ii? iioaeoei? oa aecia/aiiy ?? aeoeaiinoi aeioeieueii aeei?enoiaoaaoe iaeii/ania ianoaaeaiiy oai?iai ia iayaiinoue aioeaaio ACA oa iecueeiaaiaeieo aioeoie aei iueiai a ne?iaaooei e?iai, ui cia/ii iiaeaeuo? iioi?iaoeaiinoue eaai?aoi?ieo aeineiaeaeaiue. 5. Aenieee nooiaiue ?eceeo ?icaeoeo aa?iaoe/ii? iioaeoei? o oai?iai (caiaeii oano-ea?oe aeecueei 90%), iniaeeai i?e iayaiinoi aioeaaio ACA oa iecueeiaaiaeieo aioeoie aei iueiai, iiaea aooe ae?iaiaeiei iieacieeii aeey i?iaaaeaiiy niaoeeoi/ii? i?ioeai?onii? oa?aii?. NIENIE ?IAIO, IIOAEIEIAAIEO CA OAIITH AeENA?OAOeI? 1. Aieieiiiaa E.A., Iiuaiei A.A. Iniaeeainoi eeiiiee oa ia?aaiao aino?eo ?anii?aoi?ieo caoai?thaaiue o aeioae, iioieiaaieo ai?onii cae/aeiiai aa?iano // Ainiee i?iaeai aiieiai? ? iaaeeoeeie. - Iieoaaa-Oa?eia. - 1999. - Aei.1. - N.98-103. 2. Iiuaiei A.A., Aieieiiiaa E.A. Iniaeeainoi niaoeeoi/ii? aeiaaiinoeee aa?iaoe/ii? iioaeoei? o aeioae // Ainiee i?iaeai aiieiai? ? iaaeeoeeie. - Iieoaaa-Oa?eia. - 1999. - Aei.1. - N.107-110. 3. Aieieiiiaa E.A. Iniaeeainoi eeiiiee oa ia?aaiao aino?eo eeoeiaeo iioaeoeie o aeioae, iioieiaaieo ai?onii cae/aeiiai aa?iano // Ainiee i?iaeai aiieiai? ? iaaeeoeeie. - Iieoaaa-Oa?eia. - 1998. - Aei.2. - N.76-81. 4. Ieuaiei A.A., Iaoeae TH.A., Aaeieiiiaa E.A. Aa?iaoe/aneay eioaeoeey / Iaoiaee/aneea ?aeiiaiaeaoeee. - Oa?ueeia. - 1996. - 27n. 5. Aaeieiiiaa E.A., Ieuaiei A.A. Eioaineaiay oa?aiey ino?iai aa?iaoe/aneiai iaieiaiyioeaoaeeoa o aeaoae / Na. iao/i. ?aaio: "Iaoa?eaeu 2 iaoeeiiaeueiiai eiia?anna aianoaceieiaia Oe?aeiu". - Oa?ueeia. - 1996. - N.11. 6. Aaeieiiiaa E.A., Eacie?/oe A.A. Aa?iaoe/aneay eioaeoeey o aeaoae ?aiiaai aic?anoa // Na. iao/i. ?aaio OAIO: "Iaaeeoeeia naaiaeiy e caao?a". - Oa?ueeia, auione 2. - 1997. - N.82. 7. Aaeieiiiaa E.A. Eniieueciaaiea eaoa?iia a oa?aiee ae?onii-aaeoa?eaeueiuo eioaeoeee o aeaoae ?aiiaai aic?anoa // Na. iao/i. ?aaio: "I?iaeaiu e ia?niaeoeau ia?aceoioeaiieiaee". - Oa?ueeia-Eoaaine. - 1997. - N.19-20. 8. Aaeieiiiaa E.A., Ieuaiei A.A., Iaea?aiei E.E., ?uaaeei A.I. Ioeaiea aeoeaiinoe aa?iaoe/aneie eioaeoeee i?e caaieaaaieyo i?aaiia aeuoaiey o aeaoae ?aiiaai aic?anoa // Na. iao/i. ?aaio "I?iaeaiu e ia?niaeoeau ia?aceoioeaiieiaee". - Oa?ueeia-Eoaaine. - 1997. - N.112-113. 9. Aaeieiiiaa E.A., Ieuaiei A.A. I?iaiice?iaaiea oa/aiey aa?iaoe/aneie eioaeoeee o aeaoae ?aiiaai aic?anoa // Na. iao/i. ?aaio "Aeooaeueiua aii?inu nia?aiaiiie iaaeeao?ee". - Na?aoia. - 1997. - N.55. 10. Aaeieiiiaa E.A. Eeeie/aneay ioeaiea auyaeaiey ia?ea?ia aa?iaoe/aneie eioaeoeee o aeaoae // Na. iao/i. ?aaio "Aeooaeueiua aii?inu nia?aiaiiie iaaeeao?ee". - Na?aoia.- 1997.- N.70. 11. Aieieiiiaa E.A., Iiuaiei A.A. A?oie ?eceeo uiaei iani?eyoeeaiai ia?aaiao aa?iaoe/ii? iioaeoei? o aeioae // Na. iaoeiaeo ?ia?o "Aeooaeueii ieoaiiy iioaeoieiai?". - Oa?iiiieue. - 1998. - N.324-325. 12. Eacie?/oe A.A., Eooa?ue Ae.E., Aaeieiiiaa E.A. Aa?iaoe/aneay eioaeoeey i?e iaioeiaeiuo ninoiyieyo o aeaoae // Na. iaoeiaeo ?ia?o "Aeooaeueii ieoaiiy iaaeeoeeie". - Oa?ueeia. - 1998. - N.48. 13. Eacii?/oe A.A., Cicoey I.I., Aieieiiiaa E.A. *anoioa iioieoaaiiy aeioae ai?onii aa?iano cae/aeiiai a caeaaeiinoi aiae aieo, noaoe, a?oie e?iai // Na. iaoeiaeo i?aoeue "Aeooaeueii ieoaiiy iaaeeoeeie". - Oa?eia. - 1998. - N.47. 14. Aieieiiiaa E.A., Iiuaiei A.A., Eacii?/oe A.A. Iniaeeainoi ia?aaiao aino?eo iiaaiiiie o aeioae, iioieiaaieo ai?onii cae/aeiiai aa?iano // Oac. aeii. iaoeiai-i?aeoe/ii? eiioa?aioei? i ieaioio Anioeiaoei? iioaeoeiiiinoia Oe?a?ie. - "Aieiai iniaeeainoi iioaeoeieieo oai?ia". - Ioea/aai. - 1998.- N.9-10. 15. Iiuaiei A.A., Aieieiiiaa E.A. Aieea iioieoaaiiy ai?onii aa?iano ia ia?aaia aino?eo eeoeiaeo iioaeoeie o aeioae ?aiiueiai aieo // Oac. aeii. iaoeiai-i?aeoe/ii? eiioa?aioei? i ieaioio Anioeiaoei? iioaeoeiiiinoia Oe?a?ie. - "Aieiai iniaeeainoi iioaeoeieieo oai?ia". Ioea/aai. - 1998. - N.102-103. AIIOAOeIss Aieieiiiaa E.A. E?eoa?i? aeiaaiinoeee oa ia?aaeaa/aiiy ia?aaiao aa?iaoe/ii? iieno-iioaeoei? o aeioae ?aiiueiai aieo. – ?oeiien. Aeena?oaoeiy ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoeiaeueiinoth 14.01.13 – iioaeoeieii oai?iae. Oe?a?inueeee IAeI aiiaeaiiieiai? oa iioaeoeieieo oai?ia ii. E.A.A?iiaoaanueeiai IIC Oe?a?ie, Ee?a, 1999. Aea/aii iniaeeainoi eeiii/iiai ia?aaiao aa?iaoe/ii? iieno-iioaeoei? o aeioae ?aiiueiai aieo ia oei ainoieo eeoeiaeo iioaeoeie (AEI) oa aino?eo iioaeoeie aeeoaeueieo oeyoia (AIAeO). C'yniaaii, ui o aeioae ?aiiueiai aieo i?e oyaeeeo oi?iao AEI oa AIAeO aino?a aa?iaoe/ia iiii-iioaeoeiy neeaaea? 13,1%, aino?a aa?iaoe/ia iieno-iioaeoeiy 45,8%, eaoaioia aa?iaoe/ia iieno-iioaeoeiy 41,1% i iacaeaaeii aiae aeoeaiinoi iioaeoeieiiai i?ioeano iaaaoeaii aieeaa? ia ia?aaia aeuaicia/aieo iioaeoeieieo caoai?thaaiue, ui iicia/a?oueny caieueoaiiyi o?eaaeinoi oa ae?aciinoi iniiaieo eeiiiei-eaai?aoi?ieo iieacieeia, a oaeiae iaoyaeaiiyi i?iaiico oai?iae. ?ic?iaeaii aiaiianoe/ii oa eeiiiei-eaai?aoi?ii aeiaaiinoe/ii e?eoa?i? aa?iaoe/ii? iieno-iioaeoei? o aeioae ?aiiueiai aieo, ia iiaenoaai yeeo aoea noai?aia aeiaaiinoe/ii-i?iaiinoe/ia oano-ea?oa ?? ne?eiiiaiai? aeiaaiinoeee. Eeth/iai neiaa: aa?iaoe/ia iieno-iioaeoeiy, aeiaaiinoeea i?iaiicoaaiiy, aeioe ?aiiueiai aieo. AIIIOAOeEss Aaeieiiiaa E.A. E?eoa?ee aeeaaiinoeee e i?iaiice?iaaiey oa/aiey aa?iaoe/aneie ieeno-eioaeoeee o aeaoae ?aiiaai aic?anoa. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.13 – eioaeoeeiiiua aieacie. Oe?aeineee IEE yieaeaieieiaee e eioaeoeeiiiuo aieaciae ei. E.A.A?iiaoaaneiai IIC Oe?aeiu, Eeaa, 1999. Aeenna?oaoeey iinayuaia ?ac?aaioea aiaiianoe/aneeo e eeeieei-eaai?aoi?iuo e?eoa?eaa aeeaaiinoeee aa?iaoe/aneie ieeno-eioaeoeee o aeaoae ?aiiaai aic?anoa. Oeaeue ?aaiou – oeo/oaiea aeeaaiinoeee e ii?aaeaeaiea i?iaiica aa?iaoe/aneie ieeno-eioaeoeee o aeaoae ?aiiaai aic?anoa ia iniiaa aiaeeca niaieoiiinoe aiaiianoe/aneeo e eeeieei-eaai?aoi?iuo i?eciaeia. A ?aaioa eco/aiu eeeieei-eaai?aoi?iua iniaaiiinoe oa/aiey aa?iaoe/aneie eioaeoeee ia oiia ino?uo eeoa/iuo eioaeoeee (IEE) e ino?uo eioaeoeee aeuoaoaeueiuo iooae (IEAeI); auaeaeaiu iaeaieaa eioi?iaoeaiua aeey aeeaaiinoeee i?eciaee; ii?aaeaeaii eeeieei-aeeaaiinoe/aneia cia/aiea eiioiieiae/aneeo ia?ea?ia aa?iaoe/aneie eioaeoeee o aeaoae ?aiiaai aic?anoa; ia iniiaa eeeie/aneiai iaaethaeaiey e noaoenoe/aneiai aiaeeca iieo/aiiuo aeaiiuo ninoaaeaia oano-ea?oa ne?eieiaiaie yeni?ann-aeeaaiinoeee aa?iaoe/aneie eioaeoeee. Iauaeoii enneaaeiaaiey auee 147 aeaoae a aic?anoa io 1 ianyoea aei 3 eao, iaoiaeeaoeony ia ea/aiee a iaeanoiie aeaoneie eioaeoeeiiiie eeeie/aneie aieueieoea a.Oa?ueeiaa ii iiaiaeo oyaeaeiai oa/aiey IEE e IEAeI. N?aaee aieueiuo auei 83 iaeue/eea (56,5%) e 64 aeaai/ee (43,5%). I?e ianeaaeiaaiee 147 aeaoae n IEE e IEAeI ia?ea?u aa?iaoe/aneie eioaeoeee auyaeaiu o 107 (72,8%), ec ieo o 13,1% auea aeeaaiinoe?iaaia ino?ay aa?iaoe/aneay iiii-eioaeoeey, o 45,8% ino?ay aa?iaoe/aneay ieeno-eioaeoeey, o 41,1% - eaoaioiay aa?iaoe/aneay eioaeoeey. Eioeoee?iaaiea ae?onii i?inoiai aa?iana (AIA) ieacuaaao iaaaoeaiia aeeyiea ia oa/aiea IEE e IEAeI, /oi i?iyaeyaony oaaee/aieai aeeeoaeueiinoe e eioaineaiinoe iniiaiuo neiioiiia IEE e IEAeI, a oaeaea oooaeoaieai i?iaiica caaieaaaiey. Onoaiiaeaii, /oi aa?iaoe/aneay eioaeoeey o aeaoae ?aiiaai aic?anoa, ia oiia eco/aaiuo eioaeoeeiiiuo caaieaaaiee, ia eiaao niaoeeoe/aneeo eeeie/aneeo neiioiiia, a yoi cia/eoaeueii oneiaeiyao aa aeeaaiinoeeo e auai? ?aoeeiiaeueiie oa?aiee. Aeey iiauoaiey eioi?iaoeaiinoe niaoeeoe/aneeo iaoiaeia eaai?aoi?iie aeeaaiinoeee e ioeaiee aeoeaiinoe aa?iaoe/aneie eioaeoeee i?aaeeiaeaii, iaeiia?aiaiii enneaaeiaaoue nuai?ioeo e?iae aieueiiai ia aioeaai AIA e ieceiaaeaeiua aioeoaea e iaio. Ia iniiaa eeeie/aneiai iaaethaeaiey e noaoenoe/aneiai aiaeeca iieo/aiiuo aeaiiuo ninoaaeaia oano-ea?oa ne?eieiaiaie aeeaaiinoeee aa?iaoe/aneie eioaeoeee, a eioi?oth aioee 18 iaeaieaa eioi?iaoeaiuo ec 35 eco/aaiuo aiaiianoe/aneeo e eeeieei-eaai?aoi?iuo oaeoi?ia. Eioi?iaoeaiinoue ?ac?aaioaiiie aeeaaiinoe/aneie oano-ea?ou auyaeeanue aunieie. O aeaoae, eioeoee?iaaiiuo AIA, iieo/aiiua ?acoeueoaou a n?aaeiai a 92% neo/aaa aeaaaee aiciiaeiinoue aeeaaiinoe?iaaoue aa?iaoe/aneoth eioaeoeeth e oeacuaaee ia iaaeaaii?eyoiia oa/aiea caaieaaaiey a aoaeouai. Ioeaea a yoie a?oiia ninoaaeea 8%. O aeaoae, iaeioeoee?iaaiiuo AIA, aiciiaeiinoue aicieeiiaaiey aa?iaoe/aneie eioaeoeee a n?aaeiai ninoaaeea 7%, i?ioea ?acaeoey yoiai caaieaaaiey oeacuaaee 93%. O/eouaay, /oi ia a eaaeaeii iaaeeoeeineii o/?aaeaeaiee anoue aiciiaeiinoue ianeaaeiaaoue ?aaaiea ia iaee/ea aioeaaia AIA e aioeoae e iaio, ec oano-ea?ou auee oaeaeaiu yoe oaeoi?u. Eioi?iaoeaiinoue ea?ou ianeieueei nieceeanue e o 68% eioeoee?iaaiiuo aeaoae naeaeaoaeuenoaiaaea a iieueco aeeaaiica aa?iaoe/aneie eioaeoeee, ioeaea ninoaaeea 32%. O iaeioeoee?iaaiiuo aeaoae i?ioea aeeaaiica aa?iaoe/aneie eioaeoeee oeacuaaee 64%, ia aiciiaeiinoue ?acaeoey eioaeoeee 36%. Eeth/aaua neiaa: aa?iaoe/iay ieeno-eioaeoeey, aeeaaiinoeea i?iaiice?iaaiey, aeaoe ?aiiaai aic?anoa. ANNOTATION Bilokonova L.A. Criteria of diagnostics and prognosis of herpetic mixed-infection in children of early age. – Manuscript. Thesis for academic degree of Candidate of Science (Medicine) in Speciality 14.01.13 – infections diseases. L.V.Gromashevskiy – Ukrainian Scientific Research Institute of Epidemiology and infections diseases, Ministry of Health of Ukraine, Kiev, 1999. Herpetic mixed-infection clinical course peculiarities against the back-ground of acute intestinal infection (AII) and respiratory organs infections were studied in children of early age. It was revealed that in children of early age in grave AII and respiratory organs infections acute herpetic monoinfection is found in 45,8%, latent herpetic mixed infection – in 41,1% and nevertheless of activity of infections process influences negatively on the above named infections diseases clinical course that leads to increased main clinical laboratory finding and deterioration of the prognosis of the disease. The elaboreted anamnestic and clinical laboratory diagnostic criteria for herpetic mixed infection in children of early age were the base of diagnostic – prognostic test chart for screening diagnosis. Key words: Herpetic mixed-infection, diagnostics, prognosis children of early age. NEI?I*AIIss EAI – aino?i eeoeiai iioaeoei?; AIEO – aino?i iioaeoei? aeeoaeueieo oeyoia; ACA – ai?on cae/aeiiai aa?iana. PAGE 2

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