22

I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

EE?ANUeEA IAAeE*IA AEAAeAI?ss

I?NEssAeEIEIIII? INA?OE ?i. I.E.OOIEEA

A?Ess?AA Ieueaa Ieaenaiae??aia

OAeE 616.381-002-089-084

EIIIEAENIA E?EOAAIIss IA?EOII?OO OA I?IO?EAEOEEA

EIAI ONEEAAeIAIUe

(aenia?eiaioaeueii-ee?i?/ia aeine?aeaeaiiy)

14.01.03 — o??o?a?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Ee?a — 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia o Ee?anuee?e iaaee/i?e aeaaeai?? i?neyaeeieiiii? ina?oe

?i. I.E.Ooieea IIC Oe?a?ie

IAOEIAEE EIINOEUeOAIO

aeieoi? iaaee/ieo iaoe, i?ioani? ?aaec?oianueeee Aiaoie?e Iaaeiae/,

Eao?aao Aea?aeaaii? i?ai?? Oe?a?ie, Caneoaeaiee ae?y/ iaoee ? oaoi?ee
Oe?a?ie,

caa?aeoaa/ eaoaae?e o??o?a?? oa ii?eiai? oai?iae Ee?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC Oe?a?ie

IO?Oe?EI? IIIIAIOE:

aeieoi? iaaee/ieo iaoe, i?ioani? Oiiaooe ?aai I?ieiiiae/,

aieiaiee o??o?a E?eoaaeueii-icaei?ia/iai ia’?aeiaiiy i?e Eaa?iao?
i?i?no??a Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? Caoa?ao Ieoaeei Iao?iae/,

ia/aeueiee a?enueeiai-iaaee/iiai oi?aae?iiy Neoaeae aaciaee Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? Iioithe TH??e Ieeieaeiae/,

i?ioani? eaoaae?e oaeoeueoaonueei? o??o?a?? ?1 Iaoe?iiaeueiiai
iaaee/iiai oi?aa?neoaoo ?i. I. Aiaiiieueoey IIC Oe?a?ie

I?IA?AeIA ONOAIIAA:

?inoeooo ee?i?/ii? oa aenia?eiaioaeueii? o??o?a?? AII Oe?a?ie, a?aeae?e
o??o?a?? oeoieiai-eeoeiaiai o?aeoo

Caoeno a?aeaoaeaoueny «_8_»_10__ 1999 ?. ia __11____ aiaeei?

ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.613.02 i?e Ee?anuee?e
iaaee/i?e aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea IIC Oe?a?ie
(254112, i.Ee?a, aoe. Aei?iaiaeeoeueea, 9)

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Ee?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea (254112, i.Ee?a, aoe
Aei?iaiaeeoeueea, 9)

Aaoi?aoa?ao ?ic?neaiee «_15__»___08___1999 ?ieo

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

e.i.i., aeioeaio Aaicaeye I.I.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. I?iaeaia ia?eoii?oo aoea ? caeeoa?oueny
iaeaeooaeuei?oith a aaaeii?iaeuei?e o??o?a??. I.I. Aaeoe?a iacaaa
ia?eoii?o i?eiee ia noa??th/ith i?iaeaiith. Iaoeiai-oaoi?/iee i?ia?an,
aeinyaiaiiy o??o?a?a, ?aai?iaoieia?a, ?ioiieia?a ia ae??oeee ??, ? ie
i?iaeiaaeo?ii ao?a/aoe oai?eo.

Coneeeyie aaaaoueio a/aieo ca inoaii? aeanyoe??//y ?ic?iaeai? aaaeeea?
aniaeoe iaoiaaiaco ia?eoii?oo, ui aeicaieeei noai?eoe oa ai?iaaaeeoe o
i?aeoeeo ioi?iie caei?ia»y ?yae iiaeo iaoiae?a ae?aaiinoeee oa e?eoaaiiy
oeueiai a??ciiai caoai?thaaiiy (A.A. Oaeeiia e niaao., 1981; A.ss.
Aaeue, 1987; A.E. Ainoeuaa e niaao., 1992; A.E. Iai/e/ e niaao., 1992;
E.I. Oiiaooe, 1994; TH.A. Aaeoaeoen e niaao., 1996; A.N. E.E.Ieothe e
niaao., 1996 Iieeieaae/ e niaao., 1996; A.O. Naaiei e niaao., 1996; K.
Singh, R.S. Chhina, 1993; D. Sleeman et al., 1995).

Eaoaeuei?noue i?e aeaiiio caoai?thaaii? eieeaa?oueny a?ae 13,5% aei
52,8% (A.ss. Aaeue, 1987; A.A. Caeoeaa e niaao., 1996; I.I. Iaaeianueeee
? ni?aaao., 1996; A.I. ?aaeceoianeee e niaao., 1996; A.A. Oaeeiia e
niaao., 1996; A.A. Nathens et al.,1995; G.Hubens et al., 1995).

Inoaii?i /anii a?aei?/a?oueny oaiaeaioe?y aei i?aeaeuaiiy /anoioe
ai?eii-naioe/ieo oneeaaeiaiue (A.O. Caeoeaa ? ni?aaao., 1998; A.?.
Ai?aaiei ? ni?aaao.,1998 ; A.Ae. Aeioeaiei ? ni?aaao., 1998; E.Ae.
Eaaaaeaa e niaao., 1998), ? oe? oneeaaeiaiiy a i?neyiia?aoe?eiiio
ia??iae? noaaeyoue i?ae caa?ico aeeooy oai?iai (E.E. Nooa?aa e niaao.,
1998).

Aeooaeuei?noue i?iaeaie aecia/a?oueny oaeeie oaeoi?aie:

1. Oe?ieith iioe?ai?noth ia?eoii?oo, iniaeeai i?e oaeeo caoai?thaaiiyo
ye aiaiaeeoeeo, oieaoeenoeo, ae?aceiaa oai?iaa oeoiea oa
aeaaiaaeoeyoeiaei? eeoee, iaie?aaoeo, o?aaie /a?aaii? ii?iaeieie oa
?i.

2. Aenieith eaoaeuei?noth na?aae oai?eo ia ?iciianthaeaeaiee ia?eoii?o.
Iacaaaeath/e ia canoinoaaiiy aioea?ioee?a oe?ieiai niaeo?a ae?? iiaiai
iieie?iiy, ??cieo iaoiae?a aeno?aei?ii?aeueii? aeaoieneeaoe?? i?aai?cio,
a?ia?aa?e/ii? ieneaaiaoe??, eaia?inoii??, canoinoaaiiy ?ioiiiiaeoeyoi??a
? o.ae., cia/ii? oaiaeaioe??? cieaeaiiy eaoaeueiino? ia
niinoa??aa?oueny.

3. Neeaaei?noth oa /eneaii?noth ii?ooaiue aiiainoaco i?e ia?eoii?o?,
ye? i?eaiaeyoue aei o?eaaeeo, a /anii iaiai?ioieo ci?i a i?aai?ci?, ?
iaaeinoaoiuei aea/aieie iaoiaaiaoe/ieie iaoai?ciaie, ye? aecia/athoue
oea neeaaeia caoai?thaaiiy.

O a?o/eciyi?e oa ca?oa?aei?e e?oa?aoo?? aeineoue oe?iei aena?oeai?
ieoaiiy e?eoaaiiy ia?eoii?oo. I?ioa iaaeinoaoiuei aena?oeai?
oneeaaeiaiiy ia?eoii?oo oa ?o i?io?eaeoeea, ieoaiiy «eaaaaeo»
eeoa/ieeo, aioa?ini?aoe??, a?aeiiaeaiiy ii?ooaii? i?e?ioei?e eeoa/ieeo.
O aeinooii?e e?oa?aoo?? ie ia cono??ee aeaieo i?i canoinoaaiiy
aioo??oiueiai ae?aioaaiiy /a?aaii? ii?iaeieie, yea aaco?oueny ia caeii?
iniino, o eiiieaeniiio e?eoaaii? ia?eoii?oo. ? aaaaoi ni??ieo ieoaiue,
ye? noinothoueny ae?aioaaiiy /a?aaii? ii?iaeieie.

Ca inoaii? aeanyoe??//y ii/aee a?eueo oe?iei canoiniaoaaoe eaia?inoii?th
i?e ?iciianthaeaeaieo ia?eoii?oao, i?ioa o oeueiio ieoaii? ? aaaaoi
ni??iiai ? iio?aao? iiaeaeueoiai aea/aiiy oa ooi/iaiiy iieacaiue aei
eaia?inoii??, ?? o?eaaeino?, canoinoaaiiy ni?aoe?eieo i?aia?ao?a oa ?o
aoaeoeaiino?. Ia aena?oeai? ieoaiiy ?aaa?e?oaoe?? oai?eo, ye? ia?aianee
?iciianthaeaeaiee ia?eoii?o.

Aaaaoi i?e?ii?aai?ci?a iaaoee no?eeino? aei ??cieo aioea?ioee?a,
ci?ieeeny a?ieia?/i? iniaeeaino? aii?oai?ii? i?e?ioei?e, o ca»yceo c /ei
?ioaeoe?y a o??o?a?? ciiao noaea aaaeeith oa neeaaeiith i?iaeaiith. O
ca»yceo c ?icaeoeii no?eeino? i?e?ii?aai?ci?a aei aioea?ioee?a cieceeany
aoaeoeai?noue aioea?ioeeioa?ai?? (A.O. Naaiei e niaao.,1996), a
aeenaaeoa??ic oa ?ioiinoi?an?y, ye? ni?e/eiythoueny a ?acoeueoao?
canoinoaaiiy aioea?ioee?a, noaaeyoue ia?aae e?ea?ai iiao i?iaeaio uiaei
iiooe?a i?aia?ao?a, ye? ei?aaothoue oe? ii?ooaiiy (A.I. Ciaiainueeee,
1997).

Ca»ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?th
aeeiiaii a?aeiia?aeii aei ieaio iaoeiai-aeine?aeii? ?iaioe Ee?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe (EIAII) ?i. I.E. Ooieea ye
naiino?eia oaia

(? aea?aeaaii? ?a?no?aoe?? 0197E003049), a oaeiae aiia aeeth/aia a
aea?aeaaio oaio EIAII ?i. I.E.Ooieea “Aea/aiiy ee?oeiieo oa iieaeoey?ieo
iaoai?ci?a ?icaeoeo aoi?eiieo ?ioiiaeao?oeeo?a a aenia?eiaio? ? ee?i?oe?
oa ?o ?ieue a iaoiaaiac? caoai?thaaiue. ?ic?iaea iaoiaaiaoe/iiai
iaa?oioiaaiiy ei?aeoe?? aoi?eiieo ?ioiiaeao?oeeo?a c aeei?enoaiiyi iiaeo
?ioiiei?aaoth/eo i?aia?ao?a iaioeaeii? i?e?iaee (? aea?aeaaii?
?a?no?aoe?? 0196E010160).

Iaoa ? caaea/? aeine?aeaeaiiy. I?aeaeueoe aoaeoeai?noue e?eoaaiiy oai?eo
ia ia?eoii?o, cieceoe e?euee?noue oneeaaeiaiue oa i?neyiia?aoe?eio
eaoaeuei?noue.

Aeey aeinyaiaiiy oe??? iaoe aoee iinoaaeai? oae? caaaeaiiy:

1. Aea/eoe oa i?iaanoe aiae?c aeina?aeo e?eoaaiiy oai?eo ia ia?eoii?o a
ia??iae c 1986 ii 1997 ?.?., i?iaanoe aiae?c eaoaeueiino?, iiieeie ?
oneeaaeiaiue ia?eoii?oo c ianooiiith ?ic?iaeith eeaneo?eaoe?? ia?eoii?oo
oa eiai oneeaaeiaiue.

2. Aea/eoe a aenia?eiaio? ?ieue ianiaoeeo?/ieo iaoai?ci?a aia?aiiai?io
e?ioi?aeii? oeaieie o oi?ioaaii? aoi?eiiiai ?ioiiaeao?oeeoo oeyoii
aaaaeaiiy aioeoeeoio?iiieneaeacii? ne?iaaoee oaa?eiai.

3. A aenia?eiaio? ? ee?i?oe? aea/eoe aoaeoeai?noue ae?? ia ?aiiaee
i?ioean e?ea?nueei? eiiiiceoe?? , yea neeaaea?oueny c iie?iaoeeneeienaio
(IIN), aeeiaeneaeo oa i?oacieo.

4. Aeey aaeaeaaoiiai aeai?o iaoiaeo e?eoaaiiy aea/eoe iaoiaaiac
aiaeioieneei-co ?c canoinoaaiiyi no/anieo a?io?i?/ieo iaoiae?a
aeine?aeaeaiiy i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a (IIE),
aia?aaoe/iiai iai?io, ??aiy iieaeoe na?aaeiuei? iane (INI).

5. Aea/eoe ao?ieia?/io no?oeoo?o caoaeiee?a ia?eoii?oo a aeeiai?oe? oa
i?e/eie ?icaeoeo i?neyiia?aoe?eieo ai?eieo oneeaaeiaiue, a oaeiae
aea/eoe i?e?ioei?o eeoa/ieeo oa ?? ii?ooaiiy ? ?ic?iaeoe noaio ei?aeoe??
oeeo ii?ooaiue oeyoii canoinoaaiiy a?ini?aoe?eieo i?aia?ao?a.

6. Iaa?oiooaaoe ? aeaoe ioe?ieo i?ea?iaeueiiai niiniao e?eoaaiiy
ia?eoii?oo, yeee a?oioo?oueny ia o?ceei-o?i?/iiio yaeu? iniino, oeyoii
canoinoaaiiy a?iioii?/iiai aioenaioe/iiai ?ic/eio.

7. Iaa?oiooaaoe aeioe?euei?noue ? aoaeoeai?noue canoinoaaiiy
aioa?ini?aoe??, eaca?ii? oa?ai??, iaioeae?a oeiona o eiiieaeniiio
e?eoaaii? ia?eoii?oo ia iniia? aea/aiiy aeeiai?ee a?io?i?/ieo oa
?ioiieia?/ieo iieaciee?a.

8. Aea/eoe /anoioo iaaii?iiy i?neyiia?aoe?eii? ?aie o oai?eo ia
ia?eoii?o oa ae?iaeoe iaoiaaiaoe/ii iaa?oioiaaiee iaoiae i?io?eaeoeee
aeieeiaiiy ii?ooaiiy caaithaaiiy iia?aoe?eii? ?aie.

9. Oaeineiiaeeoe iaoiaeeeo iia?aoeaiiai ao?o/aiiy i?e ?iceeoiio oa
caaaeueiiio ia?eoii?o?, ?io?aiia?aoe?eiiai «eaaaaeo» /a?aaii? ii?iaeieie
? eeoa/ieeo i?e eiai ?iooaaoe?? ? aeiaanoe iaiao?aei?noue i?iaaaeaiiy
?aiiuei? /a?acciiaeiai? aioa?ini?aoe?? aioa?inaaeai.

10. ?ic?iaeoe iaoiaeeeo «eaia?inoii??» ? ianooiieo i?ia?aiiaaieo
?aeaia?ioii?e, a oaeiae – iaoiae e?eoaaiiy aioo??oiuei/a?aaieo
aanoean?a ?c canoinoaaiiyi iiaeo ni?aoe?eieo i?aia?ao?a, ye?
aieiae?thoue i?ieiiaiaaiith aioei?e?iaiith ae??th.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. I?aeoaa?aeaeaii ia iniia?
/eneaiieo i?e?ia?ieia?/ieo aeine?aeaeaiue, ui ia?eoii?o ? iie?i?e?iaiei
caoai?thaaiiyi. Iniiaio ao?ieia?/io ?ieue i?e ia?eoii?o? a?ae?a?athoue
eeoeiaa iaee/ea oa iaeeino?eae?aeuei? aiaa?iai? caoaeieee.

Ia iniia? a?io?i?/ieo aeine?aeaeaiue ne?iaaoee e?ia? oai?eo
i?aeoaa?aeaeaii, ui aino?ee ?iciianthaeaeaiee ia?eoii?o ca nai?th
iaoiaaiaoe/iith noooth ? oaciei i?ioeanii ? noi?iaiaeaeo?oueny
a?iiene/ieie ii?ooaiiyie o oeaieiao. A e?ia? cieaeo?oueny ??aaiue AOO oa
AAeO, i?aeaeuo?oueny ai?no iiei/ii? eeneioe ? aeoeai?noue
aioeieneaeaioiiai oa?iaioo eaoaeace. A e?ia? iaeiie/othoueny i?iaeoeoe
ia?aeeniiai ieeneaiiy e?i?ae?a, iie?iaioeaee c na?aaeiueith
iieaeoey?iith ianith, ? ?o ??aaiue caeaaeeoue a?ae nooiaiy
aiaeioieneeico.

Aia?oa a oiiaao aenia?eiaioo i?iaaaeaii iiaeaethaaiiy aoi?eiiiai
?ioiiaeao?oeeoo oeyoii aaaaeaiiy uo?ai aioeoeeoio?iiieneaeacii?
ne?iaaoee (AOeOIN). Aeiaaaeaii, ui oi?ioaaiiy aoi?eiiiai ?ioiiaeao?oeeoo
iia»ycaia c ianiaoeeo?/ieie iaoai?ciaie aia?aiiai?io e?ioi?aeii?
oeaieie. Iiia?aaei? aaaaeaiiy i?aeaeine?aeiei oaa?eiai oeeoio?iio N
aeeeeea? oaiaeaioe?th aei a?aeiiaeaiiy i?ioean?a aia?aicaaacia/aiiy a
ee?oeiao e?ioi?aeieo i?aai?a. I?aeoaa?aeaeaii, ui o oai?eo ia?eoii?oii
?icaeaa?oueny aoi?eiiee ?ioiiaeao?oeeo, iniaeeai a oiene/i?e oa
oa?i?iaeuei?e noaae?yo.

Aia?oa aea/aii aeanoeaino? oa aoaeoeai?noue noai?aiiai iiaiai
aioei?e?iaiiai i?aia?aoo «?iinaeei?o» oe?ieiai niaeo?a ae?? c
i?ieiiaiaaiei aioei?e?iaiei aoaeoii. (??oaiiy i?i aeaea/o iaoaio?a ia
aeiaoiaee Oe?a?ie

? 98105639 a?ae 10.02.99; ? 98105640 a?ae 10.02.99).

Aia?oa ?ic?iaeaii ? ai?iaaaeaeaii o i?aeoeeo iiaee iaoiae i?io?eaeoeee
oa e?eoaaiiy i?neyiia?aoe?eieo ai?eieo oneeaaeiaiue o oai?eo ia
ia?eoii?o, yeee a?oioo?oueny ia i?noeaaiio canoinoaaii? iiaeo
?iiia?e?ciaaieo aioei?e?iaieo i?aia?ao?a oe?ieiai niaeo?a ae??, ye?
caaacia/othoue oi?ioee i?ioei?e?iaiee aoaeo ye ii a?aeiioaiith aei
aa?ia?a, oae ? aei iaeeino?eae?aeueieo caoaeiee?a. (??oaiiy i?i aeaea/o
iaoaioo ia aeiao?ae Oe?a?ie ? 98084207 a?ae 24.12.98).

Aia?oa aeae?eaia a?oia oai?eo ia ia?eoii?o i?aeaeuaiiai ?eceeo
aeieeiaiiy iaaii?iiy i?neyiia?aoe?eii? ?aie.

Aia?oa cai?iiiiiaaii niin?a e?eoaaiiy aioo??oiuei/a?aaieo aanoean?a ?c
canoinoaaiiyi aie?eaoe?eieo ni?aaio?a. (??oaiiy i?i aeaea/o iaoaioo ia
aeiao?ae Oe?a?ie ?98105642 a?ae 27.10.98).

I?aeoaa?aeaeaia ia aaeeeiio ee?i?/iiio iaoa??ae? aeniea ni?aoe?eia
aeaoieneeaoe?eia aoaeoeai?noue aioa?inaaeth i?e canoinoaaii? eiai aeey
aioa?ini?aoe??.

Aia?oa iaoiaaiaoe/ii aeiaaaeaia ? iaa?oioiaaia aoaeoeai?noue «eaaaaeo»
eeoa/ieeo c ianooiiith aioa?ini?aoe??th aeey i?io?eaeoeee
ia/?ieiai-ie?eiai? iaaeinoaoiino? o oai?eo ia ia?eoii?o.(?aoei?iiiceoe?y
EIAII ?2489 a?ae 19.01.89).

Aia?oa ?ic?iaeaii ? ai?iaaaeaeaii o i?aeoeeo iiaee niin?a e?eoaaiiy
ia?eoii?oo, yeee a?oioo?oueny ia o?ceei-o?i?/ieo aeanoeainoyo
a?iioii?/iiai aioenaioe/iiai ?ic/eio (Aaoi?nueea na?aeioeoai N?N?
?1732992 a?ae 15.01.92).

Aia?oa ia iniia? cai?iiiiiaaiiai iaoiaeo ae?aaiinoeee niaeie oa
caeaoiino? i?aai?cio aei niaeeiooai?aiiy ?ic?iaeaii eiiieaen
i?aaaioeaieo caoiae?a i?io?eaeoeee ?aiiuei? niaeeiai? iai?io?aeiino?
eeoa/ieea (Aaoi?nueea na?aeioeoai N?N? ?1816433 a?ae 11.10.92).

Noi?ioeueiaaii oa iaa?oioiaaii i?eioeei aeeoa?aioe?eiaaiiai i?aeoiaeo
aei eiiieaeniiai e?eoaaiiy ia?eoii?oo a caeaaeiino? a?ae eiai noaae??, a
oaeiae ?ic?iaeaii eiiieaen caoiae?a aeey i?io?eaeoeee ai?eieo
oneeaaeiaiue ia?eoii?oo. Cai?iiiiiaaia ? ai?iaaaeaeaia o i?aeoeeo
eeaneo?eaoe?y ia?eoii?oo oa eiai oneeaaeiaiue. ?ic?iaeaia oaoi?ea
eaia?inoii??, aecia/ai? iieacaiiy aei ia?.

Aia?oa cai?iiiiiaaii ? ai?iaaaeaeaii o i?aeoeeo iaoiae
aioo??oiueiii?iaeieiii? eaca?ii? oa?ai?? i?e ia?eoii?o?.
(?aoei?iiiceoe?y EIAII ? 2911 a?ae 14.10.96).

Aia?oa aeiaaaeaia iaiao?aei?noue ?aaa?e?oaoe?? oai?eo, ye? ia?aianee
?iciianthaeaeaiee ia?eoii?o.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. ?ic?iaeai? iaoiaee
aeeooa?aioe?eiaaiiai i?aeoiaeo aei e?eoaaiiy eiaeiiai oai?iai a
caeaaeiino? a?ae noaae?? ia?eoii?oo, eiai iioe?aiino?, caoaeieea, a?eo
oai?iai, noiooiuei? iaoieia?? aeicaieythoue nei?ioeoe no?iee iaaee/ii?
?aaa?e?oaoe?? oai?eo, ui aea? aacia?a/iee aeiiii?/iee aoaeo.

A ?acoeueoao? canoinoaaiiy cai?iiiiiaaiiai iaoiaeo i?io?eaeoeee
aeieeiaiiy ai?eii-naioe/ieo oneeaaeiaiue, yeee a?oioo?oueny ia
?aoaeueiiio aeiaea?aeaii? anaioeee, aeei?enoaiiy iiaeo ni?aoe?eieo
i?aia?ao?a, aioeaaeoa??aeueieo ieoie, e?euee?noue iaaii?iue iia?aoe?eii?
?aie nei?ioeeany o 2,4 ?ace.

A ?acoeueoao? eiiieaeniiai e?eoaaiiy ia?eoii?oo c canoinoaaiiyi
ni?aoe?eieo i?aia?ao?a, canoinoaaiiy eaia?inoii?? c ianooiieie
i?ia?aiiaaieie ?aeaia?ioii?yie, iiaiai iaoiaeo e?eoaaiiy ia?eoii?oo,
yeee a?oioo?oueny ia o?ceei-o?i?/ieo aeanoeainoyo a?iioii?/iiai
aioenaioe/iiai ?ic/eio, aioea?ioee?a iiaiai iieie?iiy, eiia?iiaaii?
eaca?ii? oa?ai??, ?ioiioa?ai??, a oaeiae ?iaeea?aeoaeueiiai i?aeoiaeo a
e?eoaaii? eiaeiiai oai?iai iie?ioeei ?acoeueoaoe e?eoaaiiy oai?eo, ui
aeicaieeei nei?ioeoe eaoaeuei?noue i?e ia?eoii?o? a 1,3 ?ace.

Iieiaeaiiy, ?ic?iaeai? a aeena?oaoe??, eyaee a iniiao iaoiaee/ieo
?aeiiaiaeaoe?e: «Canoinoaaiiy e?eoaaeueii-i?io?eaeoe/ieo i?aia?ao?a,
aeaioiaeaieo ia iniia? e?aii?ei?aai?/ieo aaeni?aaio?a, 1994» oa
«Ae?aaiinoeea, i?io?eaeoeea ? e?eoaaiiy ia?eoii?o?a, ni?e/eiaieo
aacnii?iaeie aiaa?iaaie oa anioe?aoe?yie i?e?ii?aai?ci?a, 1998».

Iniaenoee aianie caeiaoaa/a. A iniiao iieeaaeaii iniaenoee 25 ??/iee
aeina?ae ?iaioe ii iaaeaiith oa?i?iiai? o??o?a?/ii? aeiiiiiae oai?ei c
aino?eie caoai?thaaiiyie i?aai?a /a?aaii? ii?iaeieie. Aaoi?ii ?ic?iaeaia
i?iaeaia, aecia/aii iai?yi aeine?aeaeaiiy, aeeiiaii ca?? oa ia?iaeo
oaeoe/iiai iaoa??aeo, ee?i?/ieo niinoa?aaeaiue, ?iciiae?e oai?eo ia
a?oie.

A?eueoa /anoeia ia?aeiieo iia?aoeaieo ao?o/aiue ? ?aeaia?ioii?e o
iaaaaeaieo oai?eo aeeiiaia aaoi?ii. Aaoi?o iaeaaeeoue eeaneo?eaoe?y
ia?eoii?oo oa eiai oneeaaeiaiue. Iei ?ic?iaeaia i?ia?aia e?eoaaiiy
oai?eo ia ia?eoii?o. I?e canoinoaaii? eiiieaeniiai ni?aoe?eiiai
i?aia?aoo ?iinaaio aeyaeaia a?aenooi?noue eiai aoaeoeaiino? i?e
aiaa?iai?e iaeeino?eae?aeuei?e ?ioaeoe??, o ca»yceo c /ei aeieeea
iaiao?aei?noue noai?aiiy aioei?e?iaiiai ni?aoe?eiiai i?aia?aoo, yeee ?
aoaeoeaiei i?ioe aa?iaieo ? aiaa?iaieo caoaeiee?a. Naia ?aeay eiai
noai?aiiy , aea/aiiy aeanoeaino?, aoaeoeaiino? i?aia?aoo «?iinaeei?o» a
aenia?eiaio? oa ee?i?oe? iaeaaeeoue aaoi?o.

Aaoi?o iaeaaeeoue ?aeay aeei?enoaiiy a?iioii?/iiai aioenaioe/iiai
?ic/eio oa eiai ee?i?/iiai canoinoaaiiy. I?iaaaeaii aiae?c io?eiaieo
?acoeueoao?a. Aeeiiaii aenia?eiaioaeueia aeine?aeaeaiiy aeey aea/aiiy
aoi?eiiiai ?ioiiaeao?oeeoo ca aeiiiiiaith aioeoeeoio?iiieneaeacii?
ne?iaaoee. C?iaeaii noaoenoe/io ia?iaeo iaoa??aeo. Aeai?
aenia?eiaioaeueieo aeine?aeaeaiue, ee?i?/ieo niinoa?aaeaiue iioae?eiaai?
a iiiia?ao??, iaoiaee/ieo ?aeiiaiaeaoe?yo, aeo?iaeao, ca??eao iaoeiaeo
i?aoeue, iaoa??aeao eiioa?aioe?e, neiiiceoi?a, c»?cae?a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iaoa??aee aeena?oaoe??
aoee aeeeaaeai? oa iaaiai?ai? ia eiioa?aioe?? «Aeooaeuei? ieoaiiy
o??o?a??», Ee?a, 1990 ; eiioa?aioe??, i?enay/ai?e 75-??/iiio tha?eath
Ee?anueeiai aea?aeaaiiai ?inoeoooo oaeineiiaeaiiy e?ea??a (EAe?OE),
Ee?a, 1993; II-e Oe?a?inuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? c
iaa?aeeeaaeii? aeiiiiiae, Iaeana, 1994; iaoeiai-i?aeoe/i?e eiioa?aioe??
EAe?OE ca cae?i/aieie oa ia?ao?aeieie oaiaie IAe?, Ee?a, 1995;
?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? «Ae?aaiinoeea ?
o??o?a?/ia e?eoaaiiy caoai?thaaiue oa ooeiaeaeaiue iicaia/?ieiaeo
aeia/ieo i?ioie», Ee?a, 1996; ia?oiio A?ei?onueeiio i?aeia?iaeiiio
eiia?an? o??o?a?a, A?oaanuee, 1996; eiioa?aioe?? «Aeooaeuei? i?iaeaie
iaa?aeeeaaeii? o??o?a?? i?aai?a /a?aaii? ii?iaeieie», Ee?a, 1996; ia?o?e
iaoeiai-i?aeoe/i?e eiioa?aioe?? «A?ini?aoe?ei? iaoiaee ? i?aia?aoe a
i?io?eaeoe/i?e oa e?eoaaeuei?e i?aeoeoe?», Ee?a, 1997; eiioa?aioe??
«Aeooaeuei? i?iaeaie iaie?aaoiaaiaoia?e?a?ii? oa noaeeiii? o??o?a??»,
Ee?a, 1998; III-?e A?ei?onuee?e iaoeiai-i?aeoe/i?e eiioa?aioe??
«Aoa?aioi? ? o?ceei-o?i?/i? iaoiaee oa?ai??», Iiaeeueia, 1998.

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 59 iaoeiaeo
?ia?o. A oiio /ene? 1 iiiia?ao?y, 1 o/aiaee iin?aiee ii o??o?a??, 19
noaooae a iaoeiaeo aeo?iaeao, c ieo 6 aac ni?aaaoi??a; a ca??eao
iaoeiaeo i?aoeue 14, a oiio /ene? 7 aac ni?aaaoi??a, c»?cae?a ?
eiioa?aioe?e — 18, a oiio /ene? 5 aac ni?aaaoi??a. Aeaeaii iaoiaee/ieo
?aeiiaiaeaoe?e — 2, ai?iaaaeaeaii 6 ?aoe?iiae?caoi?nueeeo i?iiiceoe?e,
io?eiaii 2 aaoi?nueeeo na?aeioeoaa oa 4 ??oaiiy i?i aeaea/o iaoaio?a
Oe?a?ie ia aeiaoiaee.

No?oeoo?a aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 375 noi??ieao
iaoeiiieno. Aiia neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e,
oa?aeoa?enoeee ia»?eo?a oa iaoiae?a aeine?aeaeaiiy, ?icae?eo
aenia?eiaioaeueieo aeine?aeaeaiue ? /ioe?ueio ?icae?e?a ee?i?/ieo
aeine?aeaeaiue, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e. Nienie e?oa?aoo?e
i?noeoue 569 aeaea?ae. ?iaioa ?ethno?iaaia 54 oaaeeoeyie ? 25
iaethieaie.

INIIAIEE CI?NO ?IAIOE

Iaoa??ae ? iaoiaee aeine?aeaeaiue. A iniiao ?iaioe iieeaaeaii aeina?ae
e?eoaaiiy oai?eo ia ia?eoii?o a ia??iae c 1986 ii 1997 ?.?., ye?
ciaoiaeeeeny a o??o?a?/i?e ee?i?oe? eaoaae?e o??o?a?? oa ii?eiai?
oai?iae Ee?anueei? aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E. Ooieea (1-a
oa 2-a o??o?a?/i? a?aeae?eaiiy ee?i?/ii? e?ea?i? ? 6 «Iaaei?noa/ei»).

A ia??iae c 1986 ii 1997 ?.?. a ee?i?oe? aeeiiaii 25910 iia?aoeaieo
ao?o/aiue, c ieo 14795 oa?i?iiaeo iia?aoe?e ia i?aaiao /a?aaii?
ii?iaeieie c i?eaiaeo ??cieo aino?eo o??o?a?/ieo caoai?thaaiue.
Ia?eoii?o niinoa??aaany o 2751 oai?iai, ui noaiiaeei 18,59% a no?oeoo??
aino?eo o??o?a?/ieo caoai?thaaiue i?aai?a /a?aaii? ii?iaeieie.

I?ioyaii ia??iaeo c 1986 — 1991 ?.?. i?iaaaeaii 8073 oa?i?iiaeo
iia?aoeaieo ao?o/aiue c i?eaiaeo aino?eo o??o?a?/ieo caoai?thaaiue
i?aai?a /a?aaii? ii?iaeieie, ia?eoii?o niinoa??aaany o 1028 oai?eo, ui
noaiiaeei 12,73%. A ia??iae c 1992 — 1997?.?. i?iiia?iaaii 6722
oai?eo c i?eaiaeo aino?eo o??o?a?/ieo caoai?thaaiue i?aai?a /a?aaii?
ii?iaeieie, ia?eoii?o niinoa??aaany o 1723 c ieo, ui noaiiaeei 25,63%,
oiaoi e?euee?noue aeiaaee?a ia?eoii?oo c 1992 ?ieo ca?eueoeeany o 2
?ace.

Ca cacia/ai? aeaa ia??iaee eaoaeuei?noue ci?ithaaeany iaiaeii??aeii. Ca
ia?o? o?noue ?ie?a iiia?ei 135 oai?eo, eaoaeuei?noue noaiiaeea 13,13%,
ca ia??iae c 1992 ii 1997 ?.?. iiia?ei 170 oai?eo, eaoaeuei?noue
noaiiaeea 9,86%, oiaoi eaoaeuei?noue ciaioeeany a 1,3 ?ace.
Caeiiii??i?noue ??cieoe? iieaciee?a eaoaeueiino? aei ? i?ney
ai?iaaaeaeaiiy iiaeo iaoiae?a e?eoaaiiy ia?eoii?oo ia i?aenoaa? aeaiiai
/enea niinoa?aaeaiue iiaeia aaaaeaoe ?noioiith, ia aeiaaeeiaith, oiio,
ui oiiaa t > 2,6 aeey n<100 aeeiiaia. Iaei??th c i?e/ei iacaaeia?eueieo ?acoeueoao?a e?eoaaiiy oai?eo ia ia?eoii?o ? i?ciy aini?oae?caoe?y. Aeey aecia/aiiy i?e/ei ca?eueoaiiy e?eueeino? ia?eoii?o?a a inoaii? ?iee iaie aea/ai? no?iee aini?oae?caoe?? oai?eo c aino?ith iaoieia??th i?aai?a /a?aaii? ii?iaeieie. Ca ia??iae c 1986 – 1991 ?.?. i?ci?oa 24 aiaeei aini?oae?ciaaii 15,53% oai?eo, c 1992 - 1997 ?.?. – 51,51%, oiaoi e?euee?noue oai?eo aini?oae?ciaaieo i?ci?oa 24 aiaeei ca inoaii? 6 ?ie?a ca?eueoeeinue a 3,4 ?ace oai?eo, ui aacia?a/ii noaei iaei??th c i?e/ei ca?eueoaiiy e?eueeino? aeiaaee?a ia?eoii?oo. Aeai? aini?oae?caoe?? oai?eo i?ci?oa 24 aiaeei ca ?ieaie iaaaaeai? ia iae.1. Iae.1 A?ao?/ia cia?aaeaiiy e?eueeino? aini?oae?caaaieo oai?eo ia ia?eoii?o Ia iae.2 iaaaaeai? iieacieee caeaaeiino? oi?ie ia?eoii?oo a?ae oa?i?io aini?oae?caoe?? oai?eo. Aeey i?noeaaeo ia?eoii?o?a ia 3-4 aeiao a?aei?/a?oueny ??cea cieaeaiiy ?o, Aeey i?noeaaeo ia?eoii?o?a ia 3-4 aeiao a?aei?/a?oueny ??cea cieaeaiiy ?o, aieiaiei /eiii, ca ?aooiie ia?aoiaeo o i?noeaaia?aeiaaeiaai? aai ?iciianthaeaeai? oi?ie. Iae/ano?oith i?e/eiith ia?eoii?oo aoa aino?ee aiiaiaeeoeeo 877 (50,9%) oai?eo, ia?oi?aoeaia aano?iaeoiaeaiaeueia ae?acea 293 (17,01%), aino?ee oieaoeenoeo 125 (7,25%), aino?ee iaie?aaoeo 84 (4,88%), ai?eii-caiaeuei? caoai?thaaiiy i?eaeaoe?a iaoee 63 (3,66%), aanoeane /a?aaii? ii?iaeieie 67 (3,89%), aino?a eeoeiaa iai?io?aei?noue oneeaaeieeany ia?eoii?oii a 41 (2,38%) aeiaaee?a. ??aeoa ia?eoii?o niinoa??aaany i?e oaeeo caoai?thaaiiyo ye cauaieaia a?eaea 12 (0,7%) aeiaaee?a. Aenieo ieoiio aaao noaiiaeoue i?neyiia?aoe?eiee ia?eoii?o 47 (2,73%) oai?eo, o?aaie /a?aaii? ii?iaeieie 36 (2,09%), o?iiaic iacaioa??aeueieo noaeei 32 (1,86%), ia?oi?aoe?y iooeeie oianoi? eeoee 21 (1,22%). Aei a?oie ?ioeo caoai?thaaiue a?aeianai?: oa?i?iaeueiee ?ea?o (2 aeiaaeee), aeeaa?oeeoe?o Iaeeaey (1), ai?eiee ia?aiao?eo (2), aieeueiee oaciaee ia?ai?ieoeo (1), ia?oi?aoe?y eeoie noi?iii?i o?eii (3), iaoo?aoe?eia oianoieeoeiaa iai?io?aei?noue iooeeiiiai aaiaco, oneeaaeiaia ia?eoii?oii (5), ia?oi?aoe?y ceiye?nii? iooeeie oeoiea (3), ?iciaae iooeeie i?aeoeoieiai? caeice (1), ?iciaae iooeeie i?eaeaoe?a iaoee c i?i?inoaiiyi a eeoeo oa na/iaee i?oo? (2), eaioea?iiaoic /a?aaii? ii?iaeieie, ?aeiaee ia?eoii?o (2), oee?ic ia/?iee, anoeeo-ia?eoii?o (1), ae?acea-?ae oeoiea c ia?oi?aoe??th (2 aeiaaeee), ui neeaei 25 (1,45%) oai?eo. ?aaeoeaia noaae?y ia?eoii?oo a?aei?/aia o 741 (43,01%) oai?iai, oiene/ia - o 831 (48,23%) ? oa?i?iaeueia - o 151 (8,76%). I?noeaaee ia?eoii?o ae?aaiinoiaaii o 624 (36,22%) oai?eo; i?noeaaia?aeiaaeiaaiee - o 235 (13,64%), aeeoociee - o 319 (18,51%), ?iceeoee - o 341 (19,79%), caaaeueiee - o 204 (11,84%). Oaeei /eiii, iaea?eueo oyaee? oi?ie ia?eoii?oo (?iceeoee oa caaaeueiee) nii-noa??aaeeny o 545 (31,16%) oai?eo. ?aaeoeaia noaae?y ia?eoii?oo a?aei?/aia o 176 (32,29%) oai?eo, oiene/ia – o 251 (46,05%), oa?i?iaeueia – o 118 (21,66%). A iniiao iiaeaeueoeo aeine?aeaeaiue iieeaaeaii aeina?ae e?eoaaiiy 435 oai?eo ?iceeoei ? caaaeueiei ia?eoii?oii ( o 66 oai?eo ae?aaiinoiaaia ?aaeoeaia noaae?y ia?eoii?oo, o 251 – oiene/ia, o 118 – oa?i?iaeueia), ye? ?icae?eai? ia 3 a?oie. Ia?oo, eiio?ieueio a?oio (EA1) neeaee oai?? ia ?iceeoee ? caaaeueiee ia?eoii?o (117 oai?eo), yeei o eiiieaeniiio e?eoaaii? i?iaiaeeany cae?eoee i?ioi/iee i?neyiia?aoe?eiee eaaaae (CIIE) /a?aaii? ii?iaeieie. Ae?oaa, eiio?ieueia a?oia (EA2) - 183 oai?eo ia ?iciianthaeaeaiee ia?eoii?o, yeei ia oii? caaaeueiii?eeiyoiai eiiieaeniiai e?eoaaiiy i?iaiaeeany cae?eoee o?aeoe?eiee i?neyiia?aoe?eiee eaaaae (COIE) /a?aaii? ii?iaeieie. O?aoy, iniiaia a?oia (IA) - 135 oai?eo ia ?iciianthaeaeaiee ia?eoii?o, yeei ia oii? eiiieaeniiai e?eoaaiiy aei /a?aaii? ii?iaeieie aaiaeeany a?iioii?/iee aioenaioe/iee ?ic/ei. ?iciiae?e oeacaieo oai?eo a caeaaeiino? a?ae i?e/eie ia?eoii?oo ianooii?: ia?oi?aoeaia aano?iaeoiaeaiaeueia ae?acea niinoa??aaeany o 98 (22,5%) oai?eo, aino?ee aiiaiaeeoeeo – o 83 (19,1%), aino?ee iaie?aaoeo – o 49 (11,3%), i?neyiia?aoe?eiee ia?eoii?o – o 44 (10,1%), o?iiaic iacaioa??aeueieo noaeei –o 32 (7,4%), o?aaie /a?aaii? ii?iaeieie – o 27 (6,2%), caiaeuei? i?ioeane i?eaeaoe?a iaoee – o 21 (4,8%), ia?oi?aoe?y iooeeie oianoi? eeoee – o 17 (3,9%), aino?ee oieaoeenoeo - o 16 (3,7%), aino?a eeoeiaa iai?io?aei?noue – o 15 (3,4%), aanoeane /a?aaii? ii?iaeieie - o 7 (1,6%), cauaieaia a?eaea – o 6 (1,4%), ?io? caoai?thaaiiy neeaee 20 (4,6%) aeiaaee?a. O EA1 ?aaeoeaia noaae?y ia?eoii?oo niinoa??aaeany o 24 (20,5%) oai?eo, oiene/ia – o 53 (45,3%), oa?i?iaeueia – o 40 (34,2%); a EA2 oe? oeeo?e noaiiaeee 26 (14,2%), 113 (61,7%), 44 (24,1%); a IA – 16 (11,9%), 85 (63,1%), 34 (25,5%) oai?eo a?aeiia?aeii. Oaeei /eiii, ?aaeoeaia noaae?y ?iceeoiai oa caaaeueiiai ia?eoii?oo o aeacaieo a?oiao niinoa??aaeany o 66 oai?eo, oiene/ia – o 251, oa?i?iaeueia – o 118. ?iciiae?e oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o a caeaaeiino? a?ae a?eo iaaaaeaii a oaaeeoe? 1. Oaaeeoey 1 ?iciiae?e oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o a caeaaeiino? a?ae a?eo Ca?aeii c iaoeie aeaieie, ia?eoii?o cono??/aany iaeiaeiai /anoi ye na?aae /ieia?e?a, oae ? na?aae ae?iie (/ieia?ee noaiiaeee 51,9%, ae?iee - 48,1%). A ee?i?oe? ?ic?iaeaia ? ai?iaaaeaeaia eeaneo?eaoe?y ia?eoii?oo oa e?eoaaeueii-ae?aaiinoe/ia i?ia?aia i?e aino?iio ia?eoii?o?. Ia aeeeeea? noii?ao i?iaaaeaiiy ei?aeoe?? ii?ooaiue aiiainoaco a ia?aae- ? i?neyiia?aoe?eiiio ia??iae?, aeeiiaiiy nai?/aniiai ? aaeaeaaoiiai iia?aoeaiiai ao?o/aiiy, canoinoaaiiy aioea?ioee?a oe?ieiai niaeo?a ae??, aioeaaeoa??aeueii? ? ?ioiioa?ai?? ? o.?i. I?ia?aia e?eoaaiiy ia?eoii?oo caaaeaee ?iaeea?aeoaeueia, iaeiae i?eioeei?aeueia noaia eiai e?eoaaiiy oi?aa?naeueia ? aeeth/a? oae? ia??iaee: I Ia?aaeiia?aoe?eiee ia??iae (o?eaae?noue 2-3 aiaeeie, aeeiio?oueny ia?aeaeueii c ae?aaiinoe/iith i?ia?aiith): - ae?aioaaiiy oeoieo iaciaano?aeueiei ciiaeii, - eaoaoa?ecaoe?y na/iaiai i?oo?a, a?aooaaiiy e?eueeino? na/?, - eaoaoa?ecaoe?y aaie (eoa?oaeueii?, i?aeeeth/e/ii?), - ei?aeoe?y aiiainoaco, - ciaaiethaaiiy, - aioeaaeoa??aeueia oa?ai?y, - i/euoaaeueia ee?cia. II Iia?aoeaia ao?o/aiiy: - aeaeaeaiiy iaoieia?/iiai ai?noo c /a?aaii? ii?iaeieie, - aaaaeaiiy o ei??iue a?eae? oiiei? eeoee 100-120 ie I,5% ?ic/eio iiaiea?io, - aeyaeaiiy oa aeaeaeaiiy aeaea?aea ia?eoii?oo, - ?io?aiia?aoe?eia naiaoe?y /a?aaii? ii?iaeieie, - ae?aioaaiiy oiiei? eeoee ca aeiiiiiaith iaci?ioanoeiaeueiiai ciiaeo i?e iayaiino? iieacaiue, - aea?? iaoiaeo caaa?oaiiy iia?aoe?? (ae?aioaaiiy /a?aaii? ii?iaeieie, aeoeaia eaia?inoii?y). III I?neyiia?aoe?eiee ia??iae: - ei?aeoe?y ii?ooaiue aiiainoaco, - aeac?ioieneeaoe?y, - aioeaaeoa??aeueia oa?ai?y, - a?aeiiaeaiiy iioi?ii? ooieoe?? eeoa/ieeo, - ?ioiiei?aeoe?y, - a?oai?iioa?ai?y, - eiiiainaoe?y aia?aaoe/ieo oa ieanoe/ieo iio?aa i?aai?cio, - i?io?eaeoeea oneeaaeiaiue. IV Ia??iae ?aaa?e?oaoe?? O a?aeiia?aeiino? c iaoith ? caaaeaiiyie aoee canoiniaai? ianooii? iaoiaee aeine?aeaeaiiy: Oai?ei aecia/aee eaeeioeeoa?iee ?iaeaen ?ioieneeaoe?? ca ss.ss. Eaeueo-Eae?oii (1941), ca A.E. Ino?ianueeei (1983). E?euee?nia aecia/aiiy i?e?ii?aai?ci?a a 1a oeaieie, a 1 ie aenoaeaoo oa ae?aaiinoeeo aeenaaeoa??ico i?iaiaeeee ca iaoiaeii A.I. Ciaiainueeiai ? ni?aaao.(1984, 1986). Aecia/aee noai ee?oeiiiai ? aoii?aeueiiai ?ioi?oaoo o oai?eo ia ?iciianthaeaeaiee ia?eoii?o. Iieacieee ii?ie aoee aecia/ai? i?e ianoaaeaii? 20 caei?iaeo aeia?iaieueoe?a. Aecia/aee: O-e?ioioeeoe a ?aaeoe?? niiioaiiiai ?icaoeiooai?aiiy c a?eo?ioeeoaie aa?aia ca I. Jondal (1972); e?euee?noue O-aeoeaieo e?ioioeeo?a (AA-?IE); A-e?ioioeeoe a ?aaeoe?? AAN-?icaoeiooai?aiiy c a?eo?ioeeoaie aa?aia ca Bjanko (1970); ??aaiue oee?eoethth/eo ?ioiieo eiiieaen?a (Oe?E) iaoiaeii i?aoeei?oaoe?? c 3,5% ?ic/eiii iie?aoeeai-ae?eieth-6000, eiioeaio?aoe?th ne?iaaoeiaeo ?ioiiaeiaoe?i?a (G,A,M) iaoiaeii ?aae?aeueii? ?ioiiaeeooc?? a aaa?iiio aae? ca Y. Manchini (1965); aeey iinoaiiaee ?aaeoe?? oaai-oeeoico canoiniaoaaee iaoiae A.O. *a?iooaiei (1978). A ne?iaaooe? e?ia? oai?eo aecia/aee INI ca I.?. Aaa??aeyi ? ni?aaao. (1984); IIE (a?ae?iia?aeene oa ae??iia? eii"thaaoe) - ca A.I. Aaa?eeiaith ? ni?aaao. (1983); aeoeai?noue eaoaeace - ca I.A. Ei?iethe ? ni?aaao. (1989); AOO, AAeO, AIO - ca W.E.Cohn et al. (1950); aia?aaoe/iee ca?yae aaeai?eiai? nenoaie - ca iaoiaeii I.TH. Eaaeaaiiaa ? ni?aaao. (1986); ai?no iiei/ii? eeneioe a ne?iaaooe? e?ia? ca iaoiaeii S.B. Barker et al. (1941); i??iaeiia?aaeii? - ca iaoiaeii TH.A. Oiaeaanueeiai (1985). Aeey ioe?iee oyaeeino? noaio oai?eo c ia?eoii?oii aei iia?aoe??, ia 3 oa 5 aeiao i?neyiia?aoe?eiiai ia??iaeo canoiniaoaaee iaoiae A?ANIA II (Adult Physiology and Chronic Health Evaluation - ioe?iea o?c?ieia?/iiai noaio ? o?ii?/ieo caoai?thaaiue o aei?ineiai), W.A. Knaus et al., (1981), a iao?e iiaeeo?eaoe??. I?e aenia?eiaioaeueieo aeine?aeaeaiiyo canoiniaoaaee oae? iaoiaee; aioeoeeoio?iiieneaeacio ne?iaaoeo (AOeOIN) aeey iiaeaethaaiiy ?ioiiaeao?oeeoo io?eiaee ca aeiiiiiaith ?ioi?caoe?? e?ie?a oeeoio?iiieneaeacith (A.O. Aioiiaiei e niaao., 1992). A naeac?ioe? uo?a aecia/aee aeoeai?noue oa?iaioo oeeoio?iiieneaeace ca W. Straus (1954); aeoeai?noue noeoeeiaoaeaa?ae?iaaiace - ca iaoiaeii I.Ae. ?uaiei ? ni?aaao. (1982); aeoeai?noue Ig-AOO-ace - ca E.I. Aeaeaeoi?nueeith (1969). A ne?iaaooe? e?ia? e?ie?a aecia/aee oeo? i?aoeei?ooth/eo aioeo?e ca E. Ioooa?eii?. Iieacieee aia?aiiai?io (AOO, AAeO, AIO) a oeion? oa naeac?ioe? uo??a aecia/aeeny ca iaoiaeii W.E. Cohn et al. (1950). I?e?ia?ieia?/i? aeine?aeaeaiiy i?iaaaeaii ni?eueii c ae.i.i., i?ioani?ii A.I.Ciaiainueeei, I.?.Naae/, ?ioiieia?/i? – e.i.i. I.O.Neo?aoianueeei, a?io?i?/i? oa aenia?eiaioaeuei? aeine?aeaeaiiy ii aea/aiith ianiaoeeo?/ieo iaoai?ci?a aia?aiiai?io e?ioi?aeii? oeaieie o oi?ioaaii? aoi?eiiiai ?ioiiaeao?oeeoo - e.a.i. I.I.Iaiueeianueeith. Noai?aiiy ni?aoe?eiiai aioei?e?iaiiai i?aia?aoo i?ieiiaiaaii? ae?? “?iinaeei?oo”, aea/aiiy eiai aeanoeaino? oa aoaeoeaiino? i?iaaaeaii ni?eueii c ae.o.i., i?ioani?ii TH.I.Oaa/aiei ? ae.i.i., i?ioani?ii A.I.Ciaiainueeei. Noaoenoe/io ia?iaeo iaoa??aeo i?iaiaeeee ia ia?niiaeueiiio eiii"thoa?? ?AI Pentium a ?ioaa?iaai?e nenoai? StatisticaR (o??ia-ae?iaiee StatsoftR Inc.,USA) aeey eiiieaeniiai noaoenoe/iiai aiae?co oa ia?iaee aeaieo a na?aaeiaeu? Windows (A.I. Ai?iaeeia,1997), a oaeiae ia?iaeyee iaoa??ae iaoiaeii aa??aoe?eii? noaoenoeee c aecia/aiiyi a??ia?aeiino? ? ca ?iciiae?eaiiyi e?eoa??th No"thaeaioa. ?acoeueoaoe aenia?eiaioaeueieo aeine?aeaeaiue. Aeine?aeaeaiiyie a/aieo onoaiiaeaii, ui i?e oyaeeeo oi?iao ia?eoii?oo ?icaeaa?oueny aoi?eiiee ?ioiiaeao?oeeo (E.A. A?thoei e niaao.,1995; A.E. Eoiaeueoeaa e niaao., 1996; E.Ae. Oineei e niaao., 1996; A.Ae. Aeoaeaiei e niaao., 1998 oa ?i.). I?e ia?eoii?o? a?aei?/a?oueny aeeneii?aeeiaoe?y an?o eaiie ?ioi?oaoo, ui ? iaeiei c iniiaieo oaeoi??a , ye? coiiaeththoue i?ia?anoaaiiy oa aaia?ae?caoe?th ?ioaeoe??. (A.E. Ainoeuaa e niaao., 1992; ss.N. Aa?acieoeeee e niaao., 1996; I.Ae. Oaianeaiei e niaao., 1996; E.N. Eniaeeia e niaao., 1997). *a?ac a?aeiia?aeaeuei?noue e?ioi?aeii? nenoaie ca niaoeeo?/io ? ianiaoeeo?/io ?acenoaioi?noue i?aai?cio, aeine?aeaeaiiy iaoai?ci?a ia?aaoaeiae iaoaaie?cio ia aia?aaoe/iiio ??ai? a e?ioi?aei?e nenoai? ia? aaaeeeaa cia/aiiy. A iao?e ?iaio? ie aeei?enoiaoaaee aenia?eiaioaeueio iiaeaeue ?ioiiaeao?oeeoo. Aeine?aeaeoaaee aieea aioeoeeoio?iiieneaeacii? ne?iaaoee ia i?ioeane aia?aicaaacia/aiiy ee?oei e?ioi?aeii? oeaieie. Ca aeiiiiiaith oe??? ne?iaaoee i?iaiaeeeiny iiaeaethaaiiy a?iiene/ieo noai?a ee?oei ?ioiii? nenoaie, aeine?aeaeoaaee o/anoue a?iaia?aaoe/ieo i?ioean?a o ia?aaoaeia? iaoaaie?cio a oiiaao ?ioiiaeao?oeeoo, a oaeiae i?iaiaeeee aecia/aiiy oa?aeoa?o oa iniaeeainoae ia?aaoaeiae aia?aiiai?io a e?ioi?aeieo i?aaiao aenia?eiaioaeueieo oaa?ei a caeaaeiino? a?ae neee ? o?eaaeino? ae?? aioeoeeoio?iiieneaeacieo aioeo?e. ?ioiiaeao?oeeo iiaeaethaaee oeyoii o?e?aciaiai aaaaeaiiy AOeOIN aioo??oiueii/a?aaeiii uo?ii (oeo? i?aoeei?ooth/eo aioeo?e 1:8, 1:64 a aeic? 0,2 ie ia 100 a ia iaeia aaaaeaiiy). Aeine?aeaeaiiy i?iaaaeai? ia 235 aacii?iaeieo uo?ao ianith 170-220 a. Iieacieee aa?iaiiai oa aiaa?iaiiai aia?aiiai?io aea/aee ia 3 oa 7 aeiao i?ney o?ueio aaaaeaiue AOeOIN a oeion? ? naeac?ioe? i?aeaeine?aeieo oaa?ei. Aecia/aee iieacieee aa?iaiiai aia?aiiai?io; aeoeai?noue OeOI, NAeA, Ig-AOO-ace a i?oioiiae??yo naeac?iee uo??a, a a aiiiaaiao? naeac?iee aecia/aee ??aaiue AOO, AAeO, AIO oa aia?aaoe/iee ca?yae. A oeion? ? naeac?ioe? aecia/aee iieaciee aiaa?iaiiai aia?aiiai?io - ??aaiue iiei/ii? eeneioe. Aeine?aeaeaiiy iieaciee?a aa?iaiiai aia?aiiai?io iieacaee, ui a caeaaeiino? a?ae aaaaeaiiy ne?iaaoee c ??cieie oeo?aie aioeo?e ?icaeaa?oueny oeaieiia a?iien?y ??ciiai nooiaiy a e?ioi?aeieo i?aaiao uo??a. Ia 3 aeiao i?ney o?e?aciaiai aaaaeaiiy AOeOIN (oeo? 1:8) a ee?oeiao naeac?iee a?aei?/aii cieaeaiiy aeoeaiino? OeOI ia 73%; cieaeaiiy ??aiy AOO- ia 50% (?<0,001); aia?aaoe/iee iioaioe?ae aaeai?eiai? nenoaie cieaeoaaany. A ee?oeiao oeiona aeoeai?noue OeOI cieaeoaaeany ia 54% (?<0,001) a ii??aiyii? c aaaaeaiiyi IEN (ii?iaeueii? e?iey/i? ne?iaaoee ) (eiio?ieueia a?oia). I?e aaaaeaii? AOeOIN c oeo?ii 1:64 i?iyaeeeny oacia? ci?ie, Oae, a i?oioiiae??yo ee?oei naeac?iee ia 3 aeiao a?aei?/aeany aeoeaaoe?y OeOI ia 65% (?<0,01); NAeA-ia 43% (?<0,01). A oeion? aeoeai?noue NAeA i?aeaeuoaaeany ia 48% (?<0,05). Ia 7 aeiao aeoeai?noue OeOI cieaeoaaeany, aeoeai?noue NAeA caeeoaeany ia oiio ae ??ai?, ui ? ia 3 aeiao. A naeac?ioe? ia 3 aeiao ii?yae c aeoeaaoe??th aeoeaiino? OeOI a?aei?/aeany a??ia?aeia aeoeaaoe?y neioaco AOO, a ia 7 aeiao ai?no AOO cieaeoaaany ia 45%, aia?aaoe/iee ca?yae aaeai?eiai? nenoaie ciaiooaaany ia 27%. Cia/ia i?eai?/aiiy aeoeaiino? OeOI a i?oioiiae??yo ee?oei naeac?iee uo??a ? iaio ae?aaeaia cieaeaiiy aeoeaiino? NAeA i?e aaaaeaii? ne?iaaoee c oeo?ii 1:8 na?ae/eoue i?i oa, ui aaaeo/ith eaieith a iaoai?ci? noi?aneaii? ae?? ne?iaaoee ? i?eai?/aiiy ieenieo i?ioean?a a oeeoio?iii?e nenoai?, aiane?aeie /iai ?icaeaa?oueny oeaieiia a?iien?y. Io?eiai? aeai? a?aeiinii ca?eueoaiiy aeoeaiino? Mg-AOO-ace, oa?iaioo, yeee aa?a o/anoue a ?aaoeyoe?? ieeniiai oinoi?eeoaaiiy AAeO, oaeiae na?ae/aoue i?i ?icaeoie oeaieiii? a?iien?? a ee?oeiao naeac?iee uo??a. Aeey aea/aiiy aieeao noi?an?? AOeOIN ia aiaa?iaio oaco aia?aiiai?io a e?ioi?aeieo i?aaiao uo??a aeine?aeaeoaaee ??aaiue iiei/ii? eeneioe - e?ioeaaiai i?iaeoeoo ae?eie?co. Ia 3 aeiao i?ney inoaiiueiai aaaaeaiiy AOeOIN c oeo?ii 1:8 a?aei?/a?oueny aeoeaaoe?y aiaa?iaii? oace ieeneaiiy aoaeaaiae?a a ee?oeiao naeac?iee. Ai?no eaeoaoo i?aeaeuoaaany ia 86% (?<0,001), ia 7 aeiao - ia 34% (?<0,05). A oeion? eaeoao i?aeaeuoaaany ia 75% (?<0,001), a ia 7 aeiao - ia 33% (?>0,05). I?e aaaaeaii?
ne?iaaoee c oeo?ii 1:64 a oeion? ? naeac?ioe? ia 3 aeiao, eiee
a?aei?/a?oueny aeoeaaoe?y neioaco AOO, niinoa??aaeiny iacia/ia
i?aeaeuaiiy ??aiy eaeoaoo: a naeac?ioe? ia 22%, a oeion? ia 19%
(?>0,05). Ia 7 aeiao, eiee iai?i ioeeaioeae?a a??ia?aeii cieaeaiee, a
naeac?ioe? ai?no eaeoaoo i?aeaeuoaaany ia 128% (?<0,001), a oeion? - ia 58% (?<0,01). A aenia?eiaio? i?iaaaeaia aei?iaoaaiiy aoaeoeaiino? oeeoio?iio N aeey ei?aeoe?? aia?aaoe/ieo i?ioean?a a ee?oeiao e?ioi?aeii? oeaieie. C oe??th iaoith 10 uo?ai aaiaeeee aioo??oiueii"yciai oeeoio?ii N i?ioyaii 6 ae?a. Ii/eiath/e c 4 aeiae aaaaeaiiy oeeoio?iio N, oeei oaa?eiai aioo??oiuei/a?aaeiii aaiaeeee AOeOIN (oeo? 1:64). Oeeoio?ii N aaiaeeee ia o?c?ieia?/iiio ?ic/ei? c ?ic?aooieo 0,05 ia ia iaeia aaaaeaiiy. I?e aeine?aeaeaii? a?io?i?/ieo iieaciee?a aeyaeaia aoaeoeaia ae?y oeeoio?iio N ia ieenethaaeueii-a?aeiiaethaaeuei? i?ioeane. Oaeei /eiii, i?e aaaaeaii? uo?ai AOeOIN, yea aeeeeea? ?icaeoie aoi?eiiiai ?ioiiaeao?oeeoo aiane?aeie oi?ioaaiiy oeaieiii? a?iien??, a?aei?/a?oueny oaciaee oa?aeoa? i?ioean?a aia?aicaaacia/aiiy a ee?oeiao e?ioi?aeieo i?aai?a i?e aaaaeaii? aioeoeeoio?iiieneaeacii? ne?iaaoee c ??ciei oeo?ii aioeoa?iaioieo aioeo?e. Iiia?aaei? aaaaeaiiy oeeoio?iio N uo?ai c aoi?eiiei ?ioiiaeao?oeeoii aeeeeea? oaiaeaioe?th aei a?aeiiaeaiiy i?ioean?a aia?aicaaacia/aiiy a ee?oeiao e?ioi?aeieo i?aai?a, ui iaoiiaeth? iaiao?aei?noue aeeth/aiiy aei eiiieaenii? oa?ai?? oai?eo ia ia?eoii?o i?aia?aoo oeeoio?iio N. Ianooiia aenia?eiaioaeueia aeine?aeaeaiiy aoei i?iaaaeaia aeey aea/aiiy aoaeoeaiino? iiaiai aioei?e?iaiiai i?aia?aoo i?ieiiaiaaii? ae??, iacaaiiai "?iinaeei?o". I?iaaaeai? iaie i?e?ia?ieia?/i? aeine?aeaeaiiy iieacaee 100% ianaiai?iiy i?e?ii?aai?ciaie iiaa?oi? ?aie oai?eo ia ai?eiee ia?eoii?o ia e?iaoeue iia?aoe??, ??aaiue yeiai /anoi ia?aaeuoaaa e?eoe/iee. I?io?eaeoeea ai?eii-caiaeueieo oneeaaeiaiue ? aeooaeueiith i?iaeaiith o??o?a??. Ana aeuacacia/aia aeeeooaaei iaiao?aei?noue noai?aiiy aoaeoeaieo i?aia?ao?a aeey i?io?eaeoeee oa e?eoaaiiy ai?eii-caiaeueieo oneeaaeiaiue. Ca inoaii? aeanyoe??//y aaaaoueia a/aieie aeiaaaeaia aeii?ioth/a ?ieue a o??o?a?/i?e ?ioaeoe?? aiaa?iaieo iaeeino?eae?aeueieo caoaeiee?a (TH.I. Aaeieo?ia e niaao., 1989; AE.I. Aaa?ee e niaao., 1989; E.E. Ieothe e niaao.,1989; A.I.Aeaoeaiei e niaao., 1995; A.E. Iai/e/ e niaao., 1998; ?.I. A?eaiei ? ni?aaao.,1999). Iaeaoaeoeai?oeie i?aia?aoaie aeey e?eoaaiiy aiaa?iaii? ?ioaeoe?? ? iao?ii?aeacie ? i?oacie, ye? oe?iei canoiniaothoueny a iaaee/i?e i?aeoeoe? i?noeaai o aeaeyae? i?ie, aa?icieth (E.A. Eaaiia e niaao., 1989; A.I. Eieania e niaao.,1989; E.A. Aeaooi e niaao., 1989; I.Ae. Iaoeianeee, 1997). Noai?aiee iiaee eiiieaeniee i?aia?ao ia iniia? iie?iaoeeneeienaio aeey i?noeaaiai e?eoaaiiy o??o?a?/ii? ?ioaeoe??, yeee ia? aoaeoeaio i?ieiiaiaaio aioei?e?iaio ae?th ii a?aeiioaiith aei aiaa?iaieo oa aa?iaieo caoaeiee?a, a oaeiae aea/ai? eiai o?ceei-o?i?/i? aeanoeaino? ? ?ic?iaeaiee niin?a eiai io?eiaiiy. I?aia?ao "?iinaeei?o" ? ianoiiiae?aiith aai ii?ioeiiiae?aiith eiiiiceoe??th a?ae?iaaeth aai ena?iaaeth iaoeee?aii??ai? eeneioe c ?iiia?e?ciaaiei ia iueiio aioeaaeoa??aeueiei i?aia?aoii i?oacieii, ?ic/eiaiei a aeeiaeneae? (AeINI). Aeyaeaii, ui ?iiia?e?caoe?y i?oacieo ia IIN o e?eueeino? a?ae 0,3 aei 0,5 a ia 10 a IIN a i?enooiino? aeeiaeneaeo i?eaiaeeoue aei iaia?aaeaa/aiiai aoaeoo: c"yaey?oueny aeniea, a?eueoa i?ae o IIN ? i?oacieo, ie?aii ? ?acii acyoeo, i?ioei?e?iaia aeoeai?noue ii a?aeiioaiith aei oe?ieiai niaeo?a iaoiaaiii? aa?iaii? oa aiaa?iaii? i?e?ioei?e. Aeai? aenia?eiaioaeueieo aeine?aeaeaiue c aea/aiiy e?iaoeee aeani?aoe?? i?oacieo c IIN aei aaa?o iieacaee, ui iaeneiaeueia aeani?aoe?y i?oacieo c iao?eoe? a?aei?/a?oueny a ia?o? 3-4 aeiae. Ia 5 aeiao aeani?aoe?y i?oacieo ??cei iaaea?. Aioei?e?iaio ae?th ?iinaeei?oo aea/aee o aa??aio? aeeooc?? a aaa? ?c canoinoaaiiyi iiaeeo?eiaaiiai iaoiaeo "eieiaeyc?a". Aeyaeaia aeniea /ooeea?noue aei ?iinaeei?oo ye a?aiiiceoeaii?, oae ? a?aiiaaaoeaii? i?e?ioei?e, a oiio /ene? ? eeaan??ee. Ni?aoe?eii-aeaoieneeaoe?eia ae?y IIN oa ?iinaeei?oo aea/aeany a?aeiinii aecioieneio A ?s.aerugenosa (aoaeiii? ooaie), i?ioaac ? aaiie?ceio (18 ee?i?/ieo ooai?a neiueiai?eii? iaee/ee ? 8 ee?i?/ieo ooai?a cieioenoiai noao?eieiea). sse aoaeiii? i?iaeooeaioe aecioieneio A aoee aeei?enoai? ooaie ?s.aerugenosa PA-103 (NOA) oa ?A-7 (eaai?aoi??y ii?eiaeo ?ioaeoe?e ?AI ?i.I.O.Aaiae??). A aenia?eiaioao canoiniaoaaee noa?eeueiee eoeueoo?aeueiee o?eueo?ao. O o?eueo?ao? aecia/aee eiioeaio?aoe?th a?eea ca iaoiaeii I.I. Lowry (1951), o aae? - ca E. Ioooa?eii? (1953) c niaoeeo?/iith aioeoiene/iith ne?iaaoeith c aecia/aiiyi LD50 ia a?eeo ieoao. ??aaiue ni?aoe?? aaiie?cei?a ? i?ioaac i?ney 2-aiaeeiiiai eiioaeoo noaiiaea a?ey 100%. O?eueo?aoe, ye? i?noyoue aecioienei A neiueiai?eii? iaee/ee, i?ney ia?iaee ?iinaeei?oii iiai?noth ao?a/athoue eaoaeueio aeoeai?noue. Aea/aia oa?iaeie?iaoeea i?oacieo, yeee aeani?ao?oueny a ?aio c ?iinaeei?oo. Eiioeaio?aoe?y i?oacieo a ?aiia?e oeaiei? i?ioyaii o?ueio ae?a eieeaaeany a iaaeao 90,0-38,4 iea/a. A e?ia? iii?oia i?aeaeuaiiy eiioeaio?aoe?? i?oacieo ia niinoa??aaeiny. ?iinaeei?o i?iyaea aenieo aioei?e?iaio niaoeeo?/io aeoeai?noue "in vivo". Iiaeaethaaiiy i?noeaai? aaeoa?i?aeii? ?ioaeoe?? i?iaiaeeeiny ia ii?nueeeo naeieao aaaith 250-300 a ? e?ieyo ii?iaee "Oeioeea" aaaith 2,5-3,0 ea. Canoiniaoaaeeny ooaie A.fragilis 323 oa A.melaninogenicus (iocaeiee ooai). Iiaeaethaaeany oe??ii-i"yciaa ?aia c ianooiiei ?io?eoaaiiyi ?? i?e?iaiith noniaic??th ia o?c?ieia?/iiio ?ic/ei? a eiioeaio?aoe?? 1,5o1010 i?e?iaieo ee?oei a 1 ie aeey ii?nueeeo naeiie ? 3,0o1010 - aeey e?ie?a. Eiio?ieueio a?oio oaa?ei e?eoaaee 10% ?ic/eiii oei?enoiai iao??th c ianooiieie iacaaeie iia"yceaie . Aeine?aeio a?oio oaa?ei e?eoaaee ?iinaeei?oii, yeee aiineee a ?aio ii 2 ni3 iaeie ?ac ia aeiao (e?eoaaeueia aeica). Caai?iiy ?aie a eiio?ieuei?e a?oi? a?aei?/aii /a?ac 17,8 + 3,2 ae?a, a aeine?aei?e a?oi? - /a?ac 11,2 + 2,1 ae?a (?<0,05). ?iinaeei?o o aeine?aeao "in vivo" iieacaa aenieo aoaeoeai?noue i?e i?noeaa?e aiaa?iai?e iaeeino?eae?aeuei?e ?ioaeoe??. Aenieee i?ioeaio iie?aeano?a o ?ai? ia 5-6 aeiao na?ae/eoue i?i oi?ioo ?aaaia?aoeaio ?aaeoe?th i?ae aieeaii ?iinaeei?oo. ?acoeueoaoe ee?i?/ieo aeine?aeaeaiue. Oai?eo anaa?/ii ianoaaeoaaee. Iaoiaee ae?aaiinoeee aoee ni?yiiaai? ia ooi/iaiiy noaae?? ia?eoii?oo, ??aiy aiaeioieneeico, ?ioiieia?/ieo iieaciee?a, i?e?ia?ieia?/ieo aeaieo ? o.ae. Iieacieee iiae?o?eiaaii? APACHE II a aeine?aeaeoaaieo a?oiao oai?eo ia ?iceeoee ? caaaeueiee ia?eoii?o nooo?ai ia a?ae??ciyeeny. Caaaeueia noia aae?a a EA1 neeaea 5,48 + 0,32 aae?a, a EA2 - 6,17+0,24, a IA - 5,99 +0,28 aae?a (?>0,05). A a?oiao oai?eo, aea na?aaei?e aae nenoaie APACHE
II aoa a iaaeao: EA1 — 2,40 +0,41 aae?a; EA2 — 2,23 +0,28; IA — 3,60 +
0,26 — ia iiia? aeiaeai oai?ee (?>0,05).

?c 66 oai?eo c ?aaeoeaiith noaae??th ia?eoii?oo iiia?ei 5 (7,5%), a c
369 oai?eo c oiene/iith oa oa?i?iaeueiith noaae??th iiia?ei 125
(33,9%).

A ia?o?e a?oi? (EA1) iiia?ei 45 oai?eo, noia aae?a iiaeeo?eiaaii? APACHE
II o iiia?eeo aeyaeeany aeinoia??ii aeua (?<0,001) ? neeaea 12,24 +0,93. A ae?oa?e a?oi? (EA2) iiia?ei 57 oai?eo, noia aae?a neeaea 12,85 +0,43 ? a o?ao?e a?oi? (IA) iiia?ei 28 oai?eo, noia aae?a - 13,10+ 0,55. ??cieoey a eaoaeueiino? i?ae EA1 ? IA noaoenoe/ii aeinoia??ia. (t=3,26 i?e ?<0,05). ??cieoey a ??ai? eaoaeueiino? i?ae EA2 ? IA oaeiae noaoenoe/ii aeinoia??ia (t= 2,6, i?e ?<0,05). I?e?ia?ieia?/i? aeine?aeaeaiiy aenoaeaoo /a?aaii? ii?iaeieie aeicaieeee aeyaeoe iniaeeaino? i?e?ioei?e oa ?? aeaeiaee neeaae, /ano?oa anueiai ie niinoa??aaee oae? anioe?aoe??: E.coli oa Bacteroides; Bacteroides;Citrobacter oa Candida; Fusobacterium oa Propioniobacter. I?e ai?eieo ia?eoii?oao - A.nil?, aiaa?iai? eiee; E.coli, Proteus oa Bacteroides; E.coli, Pseudomonas aerugenosa oa aiaa?iai? eiee; E.coli, Bacteroides oa aiaa?iai? eiee; E.coli, Clostridium oa aiaa?iai? eiee; Fusobacterium, Propioniobacterium oa ?i. Oaeei /eiii, ia?eoii?o ? iie?i?e?iaiei caoai?thaaiiyi. Iaei??th c i?ia?aeieo eaiie a iaoiaaiac? ia?eoii?oo ? ?oai?/i? ooeiaeaeaiiy (E.A. A?thoei e niaao., 1995; I.A. Aii/a? e niaao., 1996; Aeae. A. Eioo?ae, 1996; A.A. Ee?eianeee, 1997). Aeoiaey/e c oiai, ui a iaoiaaiac? ia?eoii?oo ?oai?/iei ooeiaeaeaiiyi a?aeaiaeeoueny aaaeeeaa ?ieue ? no?ania? ?aaeoe?? i?io?eathoue c o/anoth a?iaia?aaoe/ieo i?ioean?a, a e?ia? 102 oai?eo ia ?iceeoee ? caaaeueiee ia?eoii?o a ??cieo noaae?yo caoai?thaaiiy aeine?aeaeoaaee ??aaiue aaeai?eiaeo ioeeaioeae?a (AOO, AAeO, AIO) , ai?no iiei/ii? ? i??iaeiia?aaeii? eeneio, i?iaeoeo?a IIE. A ?aaeoeai?e noaae?? aei e?eoaaiiy aeyaeaii aeinoia??ia cieaeaiiy AOO ia 64% (?<0,05) ; AAeO - ia 63% (?<0,05) a ii??aiyii? c ii?iith. A oiene/i?e noaae?? ??aaiue AOO cieaeaiee ia 49% (?<0,05); AAeO - ia 44% (?<0,05). A oa?i?iaeuei?e noaae?? cieaeaiiy AOO cacia/aii ia 72%, AAeO - ia 74%. Noia ioeeaioeae?a a ?aaeoeai?e noaae?? cieaeoaaeany ia 57% (?<0,05); a oiene/i?e - ia 42% (?<0,05); a oa?i?iaeuei?e - ia 67% (?<0,05). A on?o noaae?yo cacia/aeiny cia/ia i?aeaeuaiiy ??aiy i?iaeoeo?a IIE, ui na?ae/eoue i?i ooieoe?iiaeuei? ii?ooaiiy ??cieo eaiie aioeieneaeaioiiai caoenoo. O??o?a?/ia oa iaaeeeaiaioicia e?eoaaiiy oai?eo a ?aaeoeai?e noaae?? aino?iai ia?eoii?oo ni?ey? cia/iiio a?aeiiaeaiith a?eueii?aaeeeaeueiiai ieeneaiiy e?i?ae?a oa iieaciee?a a?iiene/ieo noai?a aei 7-10 ae?a i?ney iia?aoe??. Oae, a ?aaeoeai?e noaae?? ??aaiue AOO a?aeiiaeany ia 68%, AAeO - ia 77%, noia ioeeaioeae?a - ia 72% (?<0,05). A oiene/i?e noaae?? a i?ioean? e?eoaaiiy ??aaiue AOO a?aeiiaeany ia 84%, AAeO - ia 82%, noia ioeeaioeae?a - ia 83% (?<0,05). A oa?i?iaeuei?e noaae?? ??aaiue AOO a?aeiiaeany anueiai ia 41%, AAeO - ia 42%, a noia ioeeaioeae?a ia 46% (?<0,05). ??aaiue i?iaeoeo?a IIE a ?aaeoeai?e noaae?? aei 7-10 ae?a iaaeeaeaany aei ii?ie. A oiene/i?e noaae?? a?i caeeoaany i?aeaeuaiei ia 93% ? neeaa 3,4 iae/ie a ii??aiyii? ?c caei?iaeie iniaaie. A oa?i?iaeuei?e noaae?? ??aaiue i?iaeoeo?a IIE caeeoeany i?aeaeuaiei ia 115% (?<0,05). ??aaiue iiei/ii? eeneioe a ?aaeoeai?e noaae?? caeeoaany i?aeaeuaiei anueiai ia 19% (?>0,05), a i??iaeiia?aaeii? ia 44% (?<0,05). A oiene/i?e noaae?? ??aaiue iiei/ii? eeneioe caeeoaany i?aeaeuaiei ia 9% (?>0,05), a
i??iaeiia?aaeii? ia 55% (?<0,05). A oa?i?iaeuei?e noaae?? ??aaiue iiei/ii? eeneioe aei oeueiai oa?i?io caeeoaany i?aeaeuaiei ia 27% (?<0,05), i??iaeiia?aaeii? - ia 60% (?<0,05). Oaeei /eiii, a ?acoeueoao? i?iaaaeaiiai eiiieaeniiai e?eoaaiiy oai?eo a oiene/i?e noaae?? ia?eoii?oo, yea aeeth/aei aioa?ini?aoe?th aioa?inaaeai, aeyaeaia aeinoia??ia oaiaeaioe?y aei a?aeiiaeaiiy aeine?aeaeoaaieo iieaciee?a ia 7-10 aeiao i?ney iia?aoe??. A oa?i?iaeuei?e noaae?? ia?eoii?oo a ?acoeueoao? eiiieaeniiai e?eoaaiiy, yea aeeth/a? aioa?ini?aoe?th aioa?inaaeai, a?aei?/a?oueny oaiaeaioe?y aei a?aeiiaeaiiy ai?noo AOO oa AAeO a ii??aiyii? c iieacieeaie aei e?eoaaiiy. ??aaiue i?iaeoeo?a IIE caeeoaany ia aenieiio ??ai?, ui aeaco? ia cia/ia ii?ooaiiy a?eueii?aaeeeaeueieo i?ioean?a, ye? ia i?aeaeathoueny e?eoaaiith. Iaaei??ia aeoeaaoe?y i?ioean?a IIE iiaea aeeeeeaoe ooeiaeaeaiiy ee?oeiieo iaia?ai aeeoo?ai aaaeeeaeo i?aai?a, ui i?ecaiaeeoue aei iie?i?aaiii? iaaeinoaoiino? i?e ia?eoii?o?. Oaeei /eiii, a oiene/i?e ? oa?i?iaeuei?e noaae?yo ia?eoii?oo ?icaeaa?oueny ?aaeoe?y aiaeioieneeico, ca oeiii "no?ano", yea noi?iaiaeaeo?oueny iaeiie/aiiyi cia/ii? e?eueeino? oiene/ieo i?iaeoeo?a (INI, i?iaeoeo?a IIE). Caa?aaeaiiy oeeo iieaciee?a a ne?iaaooe? e?ia? aai ?o ??cea ca?eueoaiiy na?ae/eoue i?i i?ia?anoaaiiy ia?eoii?oo aai aeieeiaiiy ai?eii-caiaeueieo oneeaaeiaiue, iia"ycaieo c iae?icii oeaiei. I?e aino?iio ia?eoii?o?, ye i?aaeei, ia? i?noea aeenaaeain i?ae aeae?eaiiyi a /a?aaio ii?iaeieio ? aniieooaaiiyi c ia?, i?e i?aaaethaaii? ia?oiai iaae ae?oaei. I?ney onoiaiiy aeaea?aea ia?eoii?oo ? naiaoe?? /a?aaii? ii?iaeieie i?ae /an iia?aoe?? aeueoa?oth/? oaeoi?e cia/iith i??ith onoaathoueny. O?eaath/a aenoaeaoe?y a iaeaeeae/iio i?neyiia?aoe?eiiio ia??iae? ciooo? o??o?a?a aei ae?aioaaiiy /a?aaii? ii?iaeieie. Ia?eoii?o yaey? niaith ae?aaeaia aenoaeaoeaia caiaeaiiy, a ca"yceo c /ei iaiao?aei? caoiaee, ni?yiiaai? ia i?ioeae?th aenoaeaoe?? oa o?ainnoaeaoe??, a oaeiae ia iineeaiiy ?aci?aoe??. A aino??e caiaeai?e i/a?aaei? i?ioean aniieooaaiiy iaeaea oe?eeiaeoi caiaeeoueny aei ae?? o?ceei-o?i?/ieo caeii?a (A.A.Oaeeiia e niaao.,1981). Aeey onoiaiiy aeenaaeaino i?ae aeae?eaiiyi ? aniieooaaiiyi ca oiiae ii?ooaiiy aeoeaii? ooieoe?? i/a?aaeie - iieacaia ?? oei/aniaa o?ceei-o?i?/ia ei?aeoe?y. Inoaiiy iiaea aooe cae?eniaia oeyoii canoinoaaiiy iniioe/iiai oaeoi?o. A?aae??io iniioe/iiai oeneo i?ae a?iioii?/iei aioenaioe/iei ?ic/eiii, aaaaeaiei a /a?aaio ii?iaeieio, ? caiaeaieie oeaieiaie, ye? ia?aaoaathoue a noai? a?ia?ini??, caaacia/o? iineeaia aniieooaaiiy aiaee, ui noeioeth? ?aci?aoe?th, a oaeiae aaeueio? aenoaeaoe?th ? o?ainnoaeaoe?th a /a?aaio ii?iaeieio. Oeei onoaathoueny iniiaiiieiaei? oaeoi?e caiaeaiiy - iaa?ye oa a?ia?ini?y, ui ni?ey? ?aa?ano ia?eoii?oo. Aeoiaey/e c oeueiai, ye can?a , yeee iiaea noeioethaaoe ?aci?aoe?th ? iaeii/anii aaeueioaaoe aenoaeaoe?th, o?ainnoaeaoe?th, iaie ia?aii o?ceei-o?i?/ia yaeua iniino. sse aioenaioee canoiniaoaaee oo?aoeee?i, oei?aaeneaeei, aeaeaiaoienei. Nooue niiniao e?eoaaiiy ia?eoii?oo, yeee aaco?oueny ia caeii? iniino, oaea: i?ney onoiaiiy aeaea?aea ia?eoii?oo /a?aaia ii?iaeieia i?iieaa?oueny a?ia?iniiey?iei ?ic/eiii (2-2,5%) oei?enoiai iao??th c aeiaeaaaiiyi aioenaioeeo. A e?ioe? iia?aoe?? a /a?aaio ii?iaeieio aaiaeeoueny a?iioii?/iee aioenaioe/iee ?ic/ei o e?eueeino? 300-500 ie. A i?neyiia?aoe?eiiio ia??iae? ia 2-3 aeiao iiaoi?ia aaaaeaiiy aeacaiiai ?ic/eio /a?ac i?e?i??eaaoi? (Aaoi?nueea na?aeioeoai ?1732992, a?ae 15.01.92). A?iien?y eeoeiai? no?iee ? aeii?ioth/ith i?e/eiith o aeieeiaii? ? i?ia?anoaaii? no?eeiai ia?aco i?e ia?eoii?o?. Aioa?aeueia iaaeinoaoi?noue, ia aeoieo O.N.Iiiiai? ? ni?aaao. (1991), iae/ano?oa aeieea? aiane?aeie ii?ooaiiy iioi?ii? ooieoe?? eeoa/ieeo. I?e i?e?aeiaii? ii?ooaiue e?iaiia?ao a eeoeia?e no?ioe? i?ioeane o?aaeaiiy ? aniieooaaiiy iiaeooue aeinyaaoe e?eoe/iiai ??aiy (Y.A. Ia/aaa e niaao., 1993). No?eeee ia?ac oa aioa?aeueia iaaeinoaoi?noue niinoa??aa?oueny a oiene/i?e oa oa?i?iaeuei?e noaae?yo ia?eoii?oo. A eiiieaeniiio e?eoaaii? ia?eoii?oo canoiniaaia ?iooaaoe?y eeoa/ieeo o 217 (39,81%) oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o. C iaoith aeaeiii?an?? ?iooaaoe?y oiiei? eeoee i?iaaaeaia o 35 (6,42%) oai?eo, c aeaeiii?an?eii-aeaoieneeaoe?eiith iaoith - o 136 (24,95%), c i?io?eaeoe/iith iaoith - o 46 (8,44%) oai?eo. Ia?aaaao iaaea?ii iaci?ioanoeiaeuei?e ?iooaaoe??. Iaie ?ic?iaeaiee ?io?aiia?aoe?eiee ae?ae?c eeoa/ieeo (?aoei?iiiceoe?y EAe?OE ?2489 a?ae 19.01.89) ? ciiae aeey ?iooaaoe?? eeoa/ieeo (?aoei?iiiceoe?y Ee?anueeei i?nueeei oi?aae?iiyi ioi?iie caei?ia’y ?114 a?ae 01.02.82). Aioa?ini?aoe?y aioa?inaaeai i?iaaaeaia o 91 oai?iai ia ?iceeoee oa caaaeueiee ia?eoii?o ??ciiai aaiaco, a oiio /ene? o 76 oai?eo a i?neyiia?aoe?eiiio ia??iae? i?e iayaiino? ?iooaaoe?eiiai ciiaeo a oiie?e eeooe?. Aioa?inaaeue aaiaeeee a i?ina?o ciiaeo o aeaeyae? caaen? a o?c?ieia?/iiio ?ic/ei? oei?enoiai iao??th ii 30 a 3 ?ace ia aeiao. *a?ac 3-4 aiaeeie oi?eoeai AEaia ai?no eeoa/ieea aaaeothaaee (?aoei?iiiceoe?y EAe?OE ?2493 a?ae 06.02.89). Aoaeoeai?noue aioa?ini?aoe?? eiio?iethaaee ai?noii INI a ne?iaaooe? e?ia? a iea/ie. Aei aioa?ini?aoe?? ??aaiue INI neeaaeaa 1246 + 26,5, i?ney aioa?ini?aoe?? - 922,87,6 (?<0,05). Iaoiae i?inoee, aoaeoeaiee, iaoe?aeeeaee, ia iio?aao? aeiaeaoeiai? aia?aoo?e. Eaoaeuei?noue a oe?e a?oi? oai?eo aoea ia 12,3% iaioith a ii??aiyii? c eiio?ieueiith a?oiith. Aeine?aeaeaiiyie aaaaoueio a/aieo aeiaaaeaii, ui i?e neiae?ii? aiaeiaaiii? ?ioieneeaoe?? ooai?th?oueny ? iaaeoiaeeoue a e?iaio?e aaeeea e?euee?noue ?a/iaei a?eeiai? i?e?iaee iieaeoe na?aaeiuei? iane (A.ss. Aaeue, 1987, E.A. A?thoei e niaao., 1995; A.A. Ee?eianeee, 1997). Iaie i?iaaaeaii aeine?aeaeaiiy INI o 102 oai?eo (32 - c ?aaeoeaiith noaae??th ia??oii?oo, 46 - c oiene/iith ? 24 - c oa?i?iaeueiith). Na?aaei? iieacieee INI aeey ?aaeoeaii? noaae?? neeaee 725,3 +99,1iea/ie, aeey oiene/ii? - 1271,9 +185,2 iea/ie, aeey oa?i?iaeueii? - 1693,9 +194,4 iea/ie. ??aaiue INI ? ia'?eoeaiei iieacieeii, ui a?aeia?aaea? ??aaiue oienai??, ? iiaea neoaoaaoe aeeoa?aioe?eiith iciaeith noaae?e ia?eoii?oo. C 1995 ?ieo iaie ?ic?iaeaia ? ai?iaaaeaeaia a ee?i?/io i?aeoeeo eiia?iiaaia eaca?ia oa?ai?y (EEO), yea aoea canoiniaaia o 41 oai?iai ia ?iciianthaeaeaiee ia?eoii?o a eiiieaeniiio e?eoaaii? c aeiiiiiaith aia?aooAEE?-01I, ae?iaieoeoaa III "Eaca? Aano" Euea?a, yeee aeicaiey? i?iaiaeeoe iaeii/anii oa?ai?th ye /a?aiiei (aae?e-iaiiiaei) eaca?ii (aeiaaeeia oaee? 632 ii), oae ? ?io?a/a?aiiei (iai?ai?ia?aeieeiaei) eaca?ii ( aeiaaeeia oaee? 890 ii). Aeei?enoiaoaaeiny /a?acoe??ia eaca?ia ii?ii?iaiiy e?ia? (*EIE) ia ciie niiieo a?oa??e - iiooaei?noue ia aeoiae? na?oeiaiaeo 2-3 iao, o?eaae?noue i?ioeaaeo?e 20-30 oa., aeica ia naain 2,4-5 Aeae, uiaeaiii, 5-8 naain?a aai aioo??oiueiaaiia ii?ii?iaiiy e?ia? (AEIE) AIE - c iiooaei?noth ia aeoiae? na?oeiaiaeo 1,5-2 iao, o?eaae?noue i?ioeaaeo?e 25-30 oa., aeica ia naain 2,25-3,6 Aeae, uiaeaiii, 4-6 naain?a. E??i oiai, i?iaiaeeee eaca?ia ii?ii?iaiiy /a?aaii? ii?iaeieie /a?ac ae?aiaae? c aeiiiiiaith na?oeiaiaeo EI-IAI "Eia?a", Oe?a?ia, AIE, iiooaei?noue ia aeoiae? na?oeiaiaeo 1-1,8 iao, o?eaae?noue naaino 10-20 oa., aeica 0,6-1,8 Aeae, uiaeaiii, 3-5 naain?a (?aoei?iiiceoe?y EIAII ?2111 a?ae 14.10.96). I?aea?? aeic ii?ii?iaiiy i?iaiaeeany ?iaeea?aeoaeueii, ia iniia? aiae?co ?iaeea?aeoaeueii? /ooeeaino? i?aai?cio, oyaeeino? caoai?thaaiiy, aeeiai?ee eaeeia?aie, iieaciee?a ?ioi?oaoo (I.A. Iaiaeaeue, 1998). Ca inoaii? ?iee aaaaoi a/aieo i?enay/othoue nai? aeine?aeaeaiiy aea/aiith noaio ?ioiieia?/ii? ?aaeoeaiino? oai?eo c ai?eii-caiaeueieie caoai?thaaiiyie a oiio /ene? ? i?e ia?eoii?o? (A.ss.Aaeue,1987; A.A.Iiaeaaa, 1988; E.A.A?thoei e niaao., 1989; A.N.A?eneei, 1990; A.?.O?aueinueeee ? ni?aaao., 1995; ss.N.Aa?acieoeeee e niaao., 1996; I.I.Aiiaea?aiei e niaao., 1996; A.O.Caeoeaa e niaao., 1996; A.A. Eaaiaea e niaao., 1996; A.E.Eoiaeueoeaa e niaao, 1996; I.Ae.Oaianeaiei e niaao., 1996; E.Ae.Oineei e niaao., 1996; E.N.Eniaeeia e niaao., 1997; I.I.Iaeeiianeee e niaao., 1997). E?oa?aoo?i? aeai? oa aeani? ee?i?/i? niinoa?aaeaiiy aeathoue iiaeeea?noue caeeth/eoe, ui ai?eii-caiaeueiee i?ioean a /a?aaii? ii?iaeieie oa iecea oaeoi??a, ye? eiai noi?iaiaeaeothoue, i?eaiaeyoue aei ?icaeoeo aoi?eiiiai ?ioiiaeao?oeeoo. ?ioiieia?/i? aeine?aeaeaiiy i?iaaaeai? o 87 oai?eo c ?iceeoei ? caaaeueiei ia?eoii?oii. ?aaeoeaia noaae?y niinoa??aaeanue o 13 (14,9%) oai?eo, oiene/ia - o 51 (58,6%), oa?i?iaeueia – o 23 (26,5%). Ia?oa a?oia - 17 oai?eo, ye? io?eioaaee caaaeueiii?eeiyoa eiiieaenia e?eoaaiiy (eiio?ieueia a?oia). Ae?oaa a?oia - 19 oai?eo, a eiiieaeniiio e?eoaaii? io?eioaaee EEO. O?aoy a?oia - 27 oai?eo, yeei a eiiieaeniiio e?eoaaii? i?iaiaeeeany aioa?ini?aoe?y aioa?inaaeai. *aoaa?oa a?oia - 24 oai?eo, a eiiieaeni?e oa?ai?? io?eioaaee oeiae?i aai oaeoea?i ii 1 ie ia aeiao i?ioyaii 10 aei?a. Ianoaaeaiiy i?iaiaeeeiny ia 1-2 oa 7-10 aeiao i?ney iia?aoe??. Aeai? ii??aithaaeeny c aeine?aeaeaiiyie, i?iaaaeaieie o 20 caei?iaeo aeiii??a. Ia 1-2 aeiao i?ney iia?aoeaiiai ao?o/aiiy aeyaeeeny cia/i? ii?ooaiiy iieaciee?a ?ioiii? ?aaeoeaiino?. Ai?no e?ioioeeo?a a e?ia? (109/e) a ii??aiyii? ?c caei?iaeie iniaaie ciaiooaaany ia 41,3% (? 0,01), O-e?ioioeeo?a (109/e) - ia 72,3% (?<0,01), O-aeoeaieo e?ioioeeo?a (109/e) - ia 13,6% (?>0,05), ai?no O-oaeia??a — ia 60,9%, O-noi?ani??a
— ia 38,1% (?<0,05). C aieo aoii?aeueiiai ?ioi?oaoo cacia/ai? oae? ci?ie: e?euee?noue A-e?ioioeeo?a (109/e) ciaioeeanue ia 37,9% (?<0,05). Ai?no IgM (a/e) ciaioeany ia 6,9% (?>0,05), IgG — ia 20,4% (?<0,05), IgA - ia 25,0% (?<0,01), ??aaiue oee?eoethth/eo ?ioiieo eiiieaen?a (Oe?E) i?aeaeuoaaany ia 61,0% (?<0,01). Oaaioeeoa?iee ?iaeaen ciaiooaaany ia 20,5% (?<0,05), oaaioeeoa?ia /enei ca?eueoeeiny ia 14,2% (?>0,05).

C aieo aoii?aeueiiai ?ioi?oaoo ia 7-10 aeiao i?ney iia?aoe?? aeyaeaii
ca?eueoaiiy ye i?ioeaioii?, oae ? aaniethoii? e?eueeino? A-e?ioioeeo?a.
Ca?eueooaaeany eiioeaio?aoe?y IgM oa IgG ne?iaaoee.

O ianoaaeaieo iaie oai?eo a on?o a?oiao ?icaeaaany aoi?eiiee
?ioiiaeao?oeeo, yeee i?iyaeyany ye c aieo ee?oeiiiai, oae ?
aoii?aeueiiai ?ioi?oaoo. A ?acoeueoao? i?iaaaeaiiai e?eoaaiiy a
eiio?ieuei?e a?oi? oai?eo ia 7- 10 aeiao i?ioeaioiee ai?no O-e?ioioeeo?a
caeeoaany cieaeaiei, neeaaeath/e 32,0+ 1,8% (?<0,01). Aeinoia??ii iecueeei eeoaany ai?no noaiiioeyoe?e O-ee?oei (Oo ? On). ?aooa iieaciee?a ?ioiia?aie iie?auoaaeany, aea aaaaoi c ieo ia a?aeiiaethaaeeny. I?e canoinoaaii? EEO nooo?ai c?inoaei aaniethoia /enei O-e?ioioeeo?a ia 7-10 aeiao i?ney e?eoaaiiy, iaaeeaeath/eny aei ii?ie. Aeinoia??ii c?inoaea e?euee?noue O-aeoeaieo e?ioioeeo?a, aeaui ia?aaeuoth/e ii?io. Cacia/aii ca?eueoaiiy On, Oo, aea ?o ??aaiue caeeoaany ieae/a ii?ie. ??aaiue IgG ia 7-10 aeiao i?ae aieeaii EEO i?aeaeuoaaany ? eiai eiioeaio?aoe?y aeaui ia?aaeuoaaea ii?io, i?aeaeuoaaany ? ??aaiue IgA. Cacia/aii i?aeaeuaiiy oaaioeeoa?ii? aeoeaiino? iaeo?io?e?a. O oai?eo, yeei i?iaiaeeeany aioa?ini?aoe?y aioa?inaaeai, noaoenoe/ii aeinoia??ii i?aeaeuoaaany ia 7-10 aeiao ai?no O-e?ioioeeo?a. Eiioeaio?aoe?y IgM, IgA ia 7-10 aeiao iaaeeaeaeany aei ii?ie, a IgG aeaui ia?aaeuoaaei ii?io ia 14,4%. Oaaioeeoa?iee ?iaeaen oaeiae iaaeeaeaany aei ii?ie. A a?oi? oai?eo, ui io?eioaaee oeiae?i ? oaeoea?i, /a?ac 7-10 aei?a e?eoaaiiy nooo?ai ca?eueooaaany i?ioeaioiee ai?no O-e?ioioeeo?a, aea ia aeinyaaa ii?ie. Oa?ai?y, ui i?iaiaeeeany, ni?eyea a?aeiiaeaiith i?ioeaioii? ? aaniethoii? e?eueeino? A-e?ioioeeo?a. Ca?eueooaaeany e?euee?noue IgM oa IgG, aeinyaath/e ii?ie. Eiioeaio?aoe?y IgA i?aeaeuoaaeany iacia/ii. Ooieoe?iiaeueia aeoeai?noue iaeo?io?e?a a?aeiiaethaaeany. I?iaaaeai? iaie aeine?aeaeaiiy i?aeoaa?aeeee ?icaeoie ?ioiiaeao?oeeoo i?e ia?eoii?o?. EEO a?eueo aoaeoeaii a?aeiiaeth? ai?no On, aioa?ini?aoe?y aioa?inaaeai ni?eyea a?eueo cia/iiio ca?eueoaiith O-e?ioioeeo?a, ?o i?ioeaioi?e oa aaniethoi?e e?eueeino?, iaioeaee oeiona cia/i?oa, i?ae EEO oa aioa?ini?aoe?y, noeioethaaee ??no caaaeueiiai ai?noo e?ioioeeo?a o e?ia?. Iaeiae, a?aeiiaeaiiy ?ioiieo iieaciee?a o a?eueoino? oai?eo ia ?iciianthaeaeaiee ia?eoii?o ia aeaiue aeienee ia niinoa??aaeiny, ui aeeeoo? iaiao?aei?noue i?iaaaeaiiy ?ioiii? ?aaa?e?oaoe?? oa niinoa?aaeaiiy ca oaeeie oai?eie aei a?aeiiaeaiiy iieaciee?a ?ioiia?aie. C na?aaeeie 70-o ?ie?a o??o?ae ciiao iiaa?ioeeny aei iaoiaeeee "a?aee?eoiai aeeaioa" i?e e?eoaaii? oyaeeeo oi?i ia?eoii?oo (I.N. Iaeioa, 1984; A.I. Aiae?thuaiei e niaao, 1995; I.I. Aieiaoaa e niaao., 1995; E.A. Etheueei e niaao., 1996; A.O. Naaiei e niaao., 1996; A.A. Aoia?ia e niaao., 1997; H. Bartels et. al., 1992; Singh et al.,1993; J. Janczy, 1995; D. Sleeman et al., 1995). I?ia?aiiaaia eaia?inoii?y a?aeiineoueny aei iaeiiai ?c aeoeaieo niinia?a e?eoaaiiy oyaeeeo oi?i ia?eoii?oo. Iaie aecia/ai? oae? iieacieee aei i?ia?aiiaaii? eaia?inoii??: caaaeueiee ai?eiee ia?eoii?o a oa?i?iaeuei?e noaae??, eaeia? ia?eoii?oe oa ia?eoii?oe c ae?aaeaiith aiaeiaaiiith ?ioieneeaoe??th, iie?i?aaiiith iaaeinoaoi?noth; iiiaeeii? i?aeeeoeia? aanoeane; cai?ci?e? ?aeaia?ioii?? i?e i?neyiia?aoe?eiiio ai?eiiio ia?eoii?o?; ?iciianthaeaeaiee aai iaiaaeaiee ia?eoii?o a ii?aeiaii? c iae?icii i?aai?a /a?aaii? ii?iaeieie, cai/a?aaeiii? ee?oeiaeie oa iaiiaeeea?noue iiaiiai onoiaiiy aeaea?aea ia?eoii?oo; ia?eoii?o, ni?e/eiaiee aiaa?iaieie caoaeieeaie; i?ney ?aeaia?ioii?e i?e iayaiino? oioaeueiiai iaaii?iiy ?aie c iae?icii /a?aaii? no?iee; i?e i?aeic?? aeieeiaiiy iani?iiiaeiino? oa?a aianoiiico; o?iiaic iacaioa??aeueieo noaeei, i?ney cae?eniaii? o?iiaiaeoii?? oa ?acaeoe?? eeoa/ieea. I?ia?aiiaaia eaia?inoii?y canoiniaaia o 63 oai?eo. Ia?aeiia i?ia?aiiaaia eaia?inoii?y (IIEN) canoiniaaia o 39 (61,9%) oai?eo, aoi?eiia i?ia?aiiaaia eaia?inoii?y (AIEN) - o 24 (38,1%). Iaea?eueo /anoi IIEN canoiniaoaaeany o oai?eo c o?iiaicii iacaioa??aeueieo noaeei (24,1); eaeiaei ia?eoii?oii a ?acoeueoao? ia?oi?aoe?? iooeeie (20,8%); iaie?aiiae?icii (12,5); a oie /an ye AIEN /ano?oa canoiniaoaaeany i?e aaia?aiicii-ia?oi?aoeaiiio aiaiaeeoeeo? (17,9%), iaie?aiiae?ic? (12,8%), ae?aceia?e oai?ia? oeoieo oa aeaaiaaeoeyoeiaei? eeoee (10,3%), aanoeanao /a?aaii? ii?iaeieie (10,3%). Ia?oo i?ia?aiiaaio naiaoe?th /a?aaii? ii?iaeieie aeeiio?ii /a?ac 24-48 aiaeei. A a?eueoino? aeiaaee?a e?ioeaaa cae?eooy /a?aaii? ii?iaeieie aeeiioaaee /a?ac 3-4 i?ia?aiiaai? ?aeaia?ioii??, oiaoi /a?ac 9,3 + 1,4 aeiy. O 7 (11,1%) oai?eo aeeiioaaeiny a?ae 6 aei 9 ? a?eueoa i?ia?aiiaaieo ?aeaia?ioii?e. Iiia?ei 23 oai?eo. Eaoaeuei?noue neeaea 36,5%. Eaoaeuei?noue i?e caiouaieo oi?iao ca ia??iae c 1986 ii 1991 ?.?. neeaea 51,3% , oiaoi cieceeany ia 14,8%. Iaie aea/ai? oneeaaeiaiiy ia?eoii?oo ? cai?iiiiiaaia ?o eeaneo?eaoe?y. Oneeaaeiaiiy ia?eoii?oo ?icae?eai? ia 3 a?oie: ?. Oneeaaeiaiiy, iia'ycai? c iniiaiei caoai?thaaiiyi. ??. Oneeaaeiaiiy, iia'ycai? c iia?aoe??th. ???. Oneeaaeiaiiy, iia'ycai? c noiooiueith iaoieia??th. Ne?ae cacia/eoe, ui o iaeiiai e oiai ae oai?iai ia??aeei aeieeaei ii aeaa ? a?eueoa oneeaaeiaiue, ui oo?oaeithaaei ia'?eoeaii noaeeoe i?i oneeaaeiaiiy a i?ioeaioiiio a?aeiioaii?. ?iceeoee ? caaaeueiee ia?eoii?o ie niinoa??aaee o 545 oai?eo. I?ia?anoaaiiy ia?eoii?oo cacia/aii o 49 (8,9%) oai?eo. *ano?oa anueiai oea oneeaaeiaiiy niinoa??aaeiny i?e aino?iio aeano?oeoeaiiio aiaiaeeoeeo?, ia?oi?aoeai?e ae?acoe? oeoieo oa 12-oe iaei? eeoee, aeano?oeoeaiiio iaie?aaoeo? oa ?i. I?neyiia?aoe?ei? ?io?eueo?aoe cacia/ai? o 17 (3,1%) oai?eo. Aanoeane /a?aaii? ii?iaeieie - o 46 (8,4%) oai?eo. Ca eieae?caoe??th aanoeane /ano?oa anueiai niinoa??aaeeny a naeueieeia?e noioe? (19,6%), i?aa?e eeoaia?e yioe? (13,1%), na?aaeeii? (6,5%), ia?aeieinoii?/i? (13,1%). ??aeoa anueiai aanoeane eieae?coaaeeny a e?aiio i?aeae?ao?aaiaeueiiio i?inoi?? (4,4%). Nainen ie niinoa??aaee o 31 (5,7%). Ii/aoie naineno noi?iaiaeaeoaaany aiaeioiene/iei oieii o 3 (0,5%) oai?eo. ?aiiy i?neyiia?aoe?eia nia?/ia iai?io?aei?noue eeoa/ieeo niinoa??aaeany o 25 (4,6%) oai?eo. Ai?eiee ia?eoii?o niinoa??aaany o 148 oai?eo, iaaii?iiy iia?aoe?eii? ?aie aac niaoe?aeueieo i?io?eaeoe/ieo caoiae?a cacia/aii o 51 (34,5%) oai?eo, a oa?i?iaeuei?e noaae?? ia?eoii?oo - o 45,8%. Aaaio?aoe?y cacia/aia o 6 (1,1%), eeoeia? naeu? - o 9 (1,7%). ?c oneeaaeiaiue, iia’ycaieo c noiooiueith iaoieia??th aino?ee ?ioa?eo i?iea?aeo oneeaaeiea i?neyiia?aoe?eiee ia??iae o 18 (3,3%), o?iiaiaiaie?y eaaaiaai? a?oa??? o 12 (2,2%), aino?a ii?ooaiiy iiceiaiai e?iaiia?ao cacia/aii o 5 (0,9%), iiaaiii?? - o 43 (7,9%) oai?eo. Oaeei /eiii, iaea?eueo /anoei oneeaaeiaiiyi i?neyiia?aoe?eiiai ia??iaeo o oai?eo ia ia?eoii?o ? iaaii?iiy iia?aoe?eii? ?aie. Ia ca?eueoaiiy e?eueeino? iaaii?iue i?neyiia?aoe?eii? ?aie i?e ??cieo iia?aoeaieo ao?o/aiiyo aeacothoue A.I. Aooeaiei ? ni?aaao., (1995); A.?. Ae?ey ? ni?aaao., (1995); I.A. Coaeia ? ni?aaao., (1995); O.I. ?eue/aiei ? ni?aaao., (1995); I.I. Eaioei ? ni?aaao., (1995); A.E. Ainoeuaa ? ni?aaao., (1997). Ca aeaieie A.N. Cainueeiai ? ni?aaao., (1995) oaea oneeaaeiaiiy o oai?eo ia ia?eoii?o cono??/a?oueny o 32-60% oai?eo. Aeaea?aeii i?e?ioei?e, ui ni?e/eiy? ai?eii-caiaeueia oneeaaeiaiiy, iiaea aooe aeciaaiia oa aiaeiaaiia ?ioaeoe?y (A.E. Ainoeuaa e niaao., 1997). Iaoiaaiaoe/ii iaa?oioiaaiith i?e/eiith iaaii?iiy iia?aoe?eii? ?aie o oai?eo ia ia?eoii?o ? ?io?eoaaiiy ?? ai?eiei ai?noii /a?aaii? ii?iaeieie. Iaeiei c aoaeoeaieo caoiae?a i?io?eaeoeee iaaii?iiy i?neyiia?aoe?eii? ?aie ? caoeno inoaiiuei? a?ae ai?noo /a?aaii? ii?iaeieie. Iaie aecia/ai? oae? oaeoi?e ?eceeo aeieeiaiiy iaaii?iiy i?neyiia?aoe?eii? ?aie o oai?eo ia ia?eoii?o: iioeeee ? noa?a/ee a?e, ai?ei? ia?eoii?oe, oaoi?/i? o?oaeiiu? i?ae /an iia?aoe??, aeiaeaoeiaa ?icoe?aiiy ?aie, iaee??iiy, ?icoei ii?iaeienoiai i?aaio, ii?ooaiiy anaioeee, o?eaaea noeneaiiy ?aie ?aii?icoe?thaa/ai, o?eaae? iia?aoe??, oeoe?iaee ae?aaao. A ee?i?oe? ?ic?iaeaiee ? canoiniaaiee a ee?i?/i?e i?aeoeoe? iaoiae i?io?eaeoeee iaaii?iiy iia?aoe?eii? ?aie, ui iieyaa? a ianooiiiio: i?ney ?icn?eaiiy oe??e oa i?aeoe??ii? ee?oeiaeie ia anth iiaa?oith ?aie oiieei oa?ii iaiineoueny ni?aaio c ianooiiei iaeeaaeaiiyi ?aie ia?eaaith na?aaoeith, cii/aiith ?ic/eiii oei?aaeneaeeio aai aeaeaiaoieneio. Aeiaeaoeiai ?aia a?aeiaaeiao?oueny aaaiaiyiith na?aaoeith, yea ?acii c ia?eaaith i?aeoeaa?oueny aei aiiiaa?ico. I?e aeei?enoaii? aie?eaoe?eieo ni?aaio?a: iie?ni?ao, ?iinaaioo, ?iinaeei?oo iaaii?iiy iia?aoe?eii? ?aie o oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o ciaioeeeny a 2,4 ?ace ? neeaee 14,3%. Oaeei /eiii, aoaeoeaiei iaoiaeii i?io?eaeoeee iaaii?iiy iia?aoe?eii? ?aie o oai?eo ia ia?eoii?o ? canoinoaaiiy aie?eaoe?eieo ni?aaio?a - ?iinaaioa a ii?aeiaii? c ?iinaeei?oii. Aanoeane /a?aaii? ii?iaeieie ? a??ciei oneeaaeiaiiyi i?neyiia?aoe?eiiai ia??iaeo oai?eo, ui ia?aianee ia?eoii?o. E?eoaaiiy aanoean?a, ye i?aaeei, iia?aoeaia. Iaie ?ic?iaeaiee iaoiae e?eoaaiiy aioo??oiuei/a?aaieo aanoean?a, ui a?oioo?oueny ia oi?ioaaii? ?aa?iia?ii? eaia?inoiie ?c canoinoaaiiyi aie?eaoe?eieo ni?aaio?a, ui iathoue i?ieiiaiaaio aioei?e?iaio ae?th. Cai?iiiiiaaiee niin?a e?eoaaiiy aioo??oiuei/a?aaieo aanoean?a a?ae??ciy?oueny a?ae a?aeiieo oei, ui aeey i?io?eaeoeee cao?eaiiy ??aeeie o a?eueio /a?aaio ii?iaeieio inoaiiy a?aeiaaeiao?oueny ia?eaaei oaiiiiii, yeee aeaiaeeoueny /a?ac ?aio ?acii c ae?aiaaeaie, ia ?aio iaeeaaeathoue oae /a?ac an? oa?e ca Aeiiao?, oi?io?oueny ?aa?iia?ia eaia?inoiia, iiia?aaeiuei aa?aoe a ii?iaeieio aanoeano ?iinaaio a ii?aeiaii? c ?iinaeei?oii. I?e canoinoaaii? o?aaeeoe?eiiai niiniao e?eoaaiiy aioo??oiuei/a?aaieo aanoean?a ?aoeeaeea aanoeano niinoa??aaany o 3 (9,09%) oai?eo. A a?oi? oai?eo , yeei canoiniaoaaany cai?iiiiiaaiee niin?a, ?aoeeaeea?a aanoeano ie ia niinoa??aaee. Iaea?eueo iaeiaea/aiei oneeaaeiaiiyi i?neyiia?aoe?eiiai ia??iaeo o oai?eo ia ia?eoii?o ? aeenaaeoa??ic. Aeenaaeoa??ic - oea ciaioaiiy e?eueeino? eeoa/ii? iaee/ee, i?a?aoe?y ?? a ?io? ii?iaeieie, iiyaa o oeeo i?e?ia?a aaiie?oe/ii? aeoeaiino?, ca?eueoaiiy ai?noo noao?eieie?a, i?ioath (N.I. E?aniiaieiaaoe, 1989). A.?. Eoci?oeiaa (1975) iiae?ey? aeenaaeoa??ic ia 4 oi?ie. Aaoi? aaaaea?, ui noaae?y aeenaaeoa??ico ? iine?aeiaiei ?aeeiei i?ioeanii. A ia?o?e noaae?? ciaioo?oueny ai?no eaeoiaaoeee, e?euee?noue ? aeanoea?noue ?ioeo i?aaenoaaiee?a i?e?ioei?e ia ci?ith?oueny. A ae?oa?e noaae?? aeenaaeoa??ico cieeathoue a?o?aeoiaaeoa???, a eeoa/ia iaee/ea oiia?eueiaii oa?iaioo? eaeoico, a o?ao?e ia?aaaaeathoue aaiie?coth/? i?e?ii?aai?cie oa ae??aeaeaeiiiae?ai? a?eae, a /aoaa?o?e - aeieeathoue aeeaie? ii?ooaiiy neeaaeo ? aeanoeainoae i?e?ia?a, cia/ii i?aeaeuo?oueny e?euee?noue i?ioath. Aaeoa??ieia?/i? aeine?aeaeaiiy oiiei? eeoee c ii?ooaiith iioi?iith ooieoe??th iieacaee ?? iaaeeeoeiao eieii?caoe?th i?e?ii?aai?ciaie (aei 20 aeae?a) c eiioeaio?aoe??th ?o a?ae 107 aei 1112 EIA/ie. (Y.A. Ia/aaa e niaao., 1993). A nai?o aeine?aeaeaiiyo ?.I. Aiiaea?aiei, (1997) aeia?a iayai?noue aeenaaeoa??ico o an?o oai?eo (ianoaaeaii 32 iniae), iia?iaaieo c i?eaiaeo aino?eo caoai?thaaiue i?aai?a /a?aaii? ii?iaeieie ?, ui aeenaaeoa??ic i?ia?ano? a i?neyiia?aoe?eiiio ia??iae?. Canoinoaaiiy a?inii?eio aei 6 ?ac?a ia aeiao ciaioo? e?euee?noue aeiaaee?a i?ia?anoaaiiy aeenaaeoa??ico a 1,8 ?ace. Ie i?iaaee aeine?aeaeaiiy ia aeenaaeoa??ic o 28 oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o. An? aeacai? oai?? iaea?aeoaaee ianeaio aioea?ioeeioa?ai?th. Aeenaaeoa??ic ? nooiaiy ae?aaiinoiaaiee o 4 (14,28%) oai?eo, ?? nooiaiy - o 11 (39,29%), ??? - o 10 (37,72%) oa IV nooiaiy- o 3 (10,7%) oai?eo. Ei?aeoe?y aeenaaeoa??ic?a ? i?eioeeiiai iaiao?aeiith oiiaith aoaeoeaii? oa?ai?? oai?eo ia ia?eoii?o. Iaie i?iaaaeaia ii??aiyeueia aoaeoeai?noue i?aia?ao?a, ei?eaoth/eo i?e?ioei?o eeoa/ieeo (eaeoiaaeoa?eio, IIN ? eaeoiaaeth). Aeacai? i?aia?aoe i?ecia/aeeny oai?ei, ii/eiath/e c ae?oai?, o?aouei? aeiae i?neyiia?aoe?eiiai ia??iaeo. Aoa?ioe/ia aoaeoeai?noue e?eoaaiiy ioe?ithaaeany ca iayai?noth a oaeae?yo oiiaii-iaoiaaiieo i?e?ii?aai?ci?a, aaiie?oe/ieo i?e?ii?aai?ci?a, e?eueeino? a?o?aei- oa eaeoiaaeoa??e. Iaee?au? ?acoeueoaoe iaea?aeai? i?e canoinoaaii? eiiieaeniiai i?aia?aoo " Eaeoiaaeue". Canoinoaaiiy eaeoiaaeth onoaa? oiiaii-iaoiaaii? oa aaiie?oe/i? i?e?ii?aai?cie, oi?io? aenieee ai?no aooiooiiieo i?e?ia?a. Ne?ae cacia/eoe, ui o aeiaeiiai ?c ianoaaeaieo oai?eo ia iiiaio aeienee ?c noaoe?iia?o ie ia cacia/eee a?aeiiaeaiiy i?e?ioei?e eeoa/ieeo, ui aeeeoo? iaiao?aei?noue i?iaaaeaiiy ?aaa?e?oaoe?? oai?eo, ye? ia?aianee ia?eoii?o. Aiae?c e?oa?aoo?ieo aeaieo uiaei eaoaeueiino? i?e ia?eoii?o? aeyaea aea? ianoaaeie: ae?aaeaio iaiaeiicia/i?noue ? iacaaeiaieai?noue ee?i?oeeno?a ?acoeueoaoaie e?eoaaiiy oai?eo ia ia?eoii?o, ui niiioea? a/aieo aei iiooe?a oeyo?a i?io?eaeoeee ia?eoii?oo ? iie?auaiiy ?acoeueoao?a e?eoaaiiy oeueiai a??ciiai caoai?thaaiiy. Eaoaeuei?noue i?e ia?eoii?o? caeaaeeoue a?ae aaaaoueio oaeoi??a: oa?i?i?a aini?oae?caoe??, a?ae i?iaaaeaii? ia?aaeiia?aoe?eii? i?aeaioiaee, nai?/aniino? iia?aoeaiiai ao?o/aiiy, eiai aaeaeaaoiino?, ?iciianthaeaeaiino? i?ioeano, aeaaiino? caoai?thaaiiy , noaio caoenieo nee i?aai?cio, aeaeo caoaeieea (eiai a??oeaioiino? oa iaoiaaiiino?), a?eo oai?iai, noiooiuei? iaoieia??, eaae?o?eaoe?? o??o?aa, aianoac?ieiaa, cae?enithaaii? oa?ai??. Ca iaoeie aeaieie i?e i?noeaaiio ia?eoii?o? eaoaeuei?noue neeaea 1,7% (14) oai?eo, aeeoociiio - 3,2% (10) oai?eo, i?e ?iceeoiio oa caaaeueiiio - 26,8% (146) oai?eo. Eaoaeuei?noue a ?aaeoeai?e noaae?? ?iceeoiai oa caaaeueiiai ia?eoii?oo neeaea 9,1%, a oiene/i?e ? oa?i?iaeuei?e – 33,9%. O a?oe? aei 21 ?ieo ia iiia? i? iaeei oai?ee, o a?oe? 21-60 ?ie?a (i?aoeacaeaoiee a?e) iiia?ei 50 (29,5%) oai?eo, o a?oe? 60-81 ? a?eueoa iiia?ei 120 (70,5%) oai?eo. A ia?oo aeiao iiia?ei 39 (20,9%) oai?eo. I?ioyaii 1-3 ae?a ia?aaoaaiiy oai?eo a noaoe?iia?? iiia?ei 40,5% oai?eo, ui o a?eueoino? aeiaaee?a iia'ycaii c i?ciueith aini?oae?caoe??th. Eaoaeueiee e?iaoeue a ?aaeoeai?e noaae?? ia?eoii?oo aoa coiiaeaiee , a iniiaiiio, oneeaaeiaiiyie c aieo na?oeaai-noaeeiii? nenoaie, eaaai?a, no?aniaeie ae?aceaie oeoieiai-eeoeiaiai o?aeoo, e?iaioa/aie c ieo, oneeaaeiaiiyie noiooi?o caoai?thaaiue. Ai?iaaaeaeaiiy a ee?i?/io i?aeoeeo aeoeaieo iaoiae?a e?eoaaiiy ia?eoii?oo aeicaieeei iie?aueoe ?acoeueoaoe e?eoaaiiy oai?eo ia ia?eoii?o, caaaeueia eaoaeuei?noue cieceeany a 1,3 ?ace, i?e caiouaieo oi?iao ia?eoii?oo - a 1,4 ?ace. Iniiaiith i?e/eiith eaoaeueieo ?acoeueoao?a i?e ia?eoii?o? ? i?ia?anoth/ee aiaeioieneeic (74,3%), ai?eii-naioe/i? oneeaaeiaiiy (79,8%), ui i?ecaiaeyoue aei iie?i?aaiii? iaaeinoaoiino? a 84,3% aeiaaee?a. AENIIAEE 1. Ia?eoii?o - oea neeaaeia caoai?thaaiiy iie?i?e?iaii? ao?ieia??, i?e yeiio i?ia?aeiei neiioiiieiiieaenii ? aiaeioieneeic, ui ni?e/eith? aoi?eiiee ?ioiiaeao?oeeo aiane?aeie ?icaeoeo a?iiene/ieo noai?a a i?aai?ci? a on?o o?ueio noaae?yo ia?eoii?oo. Iaea?eueo ae?aaeaia a?iien?y a?aei?/a?oueny a oa?i?iaeuei?e noaae?? ia?eoii?oo, yea noi?iaiaeaeo?oueny cia/ieie ii?ooaiiyie a iai?i? aaeai?eiaeo ioeeaioeae?a, i?aeaeuaiiyi ai?noo iiei/ii? oa i??iaeiia?aaeii? eeneio a e?ia? oai?eo. 2. A aenia?eiaio? i?e aaaaeaii? uo?ai aioeoeeoio?iiieneaeacii? ne?iaaoee c ??cieie oeo?aie aioeoa?iaioieo aioeo?e, ui ni?e/eith? ?icaeoie aoi?eiiiai ?ioiiaeao?oeeoo aiane?aeie oi?ioaaiiy oeaieiii? a?iien??, cacia/a?oueny oaciaee oa?aeoa? i?ioean?a aia?aicaaacia/aiiy a ee?oeiao e?ioi?aeieo i?aai?a. Iiia?aaei? aaaaeaiiy oeeoio?iio N uo?ai c aoi?eiiei ?ioiiaeao?oeeoii aeeeeea? oaiaeaioe?th aei a?aeiiaeaiiy aia?aicaaacia/aiiy a ee?oeiao e?ioi?aeieo i?aai?a, ui coiiaeth? iaiao?aei?noue aeeth/aiiy a eiiieaenio oa?ai?th oai?eo ia ia?eoii?o i?aia?aoo oeeoio?iio N. 3. A oiene/i?e ? oa?i?iaeuei?e noaae?yo ia?eoii?oo o oai?eo ?icaeaa?oueny aoi?eiiee ?ioiiaeao?oeeo, yeee i?iyaey?oueny ii?ooaiiyi ye ee?oeiiiai, oae ? aoii?aeueiiai ?ioi?oaoo. Ae?aaeai?noue oeeo ii?ooaiue ciaoiaeeoueny a ei?aeyoeaiiio ca"yceo c oyaee?noth aiaeioieneeico. Eiia?iiaaia eaca?ia oa?ai?y ni?ey? ca?eueoaiith IgG ? IgM, iie?ioo? oaaioeeoic. Aioa?ini?aoe?y aioa?inaaeai cia/ii i?aeaeuo? ai?no O-e?ioioeeo?a, iaioeaee oeiona - noeioeththoue ??no caaaeueiiai ai?noo e?ioioeeo?a o e?ia?. A?aoiaothth/e a?aei?ii?noue a iaoai?ci? ae?? eiia?iiaaii? eaca?ii? oa?ai??, aioa?ini?aoe??, iaioeae?a oeiona, iaiao?aeii ?o aeeth/aoe a eiiieaenia e?eoaaiiy ia?eoii?oo a caeaaeiino? a?ae iieaciee?a ?ioiia?aie. 4. A iaoiaaiac? aino?iai ia?eoii?oo nooo?ao ?ieue a?ae?a?athoue ii?ooaiiy i?ioean?a aa?iaiiai aia?aicaaacia/aiiy oeaiei i?aai?cio, ui noi?iaiaeaeo?oueny iaeiie/aiiyi i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a a e?ia? oai?eo. Cia/ia iaeiie/aiiy i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a a?aei?/a?oueny a oiene/i?e ? oa?i?iaeuei?e noaae?yo. I?aeaeuaiiy aeoeaiino? iiooaeii? aioeieneaeaioii? eaiee (aeoeaiino? eaoaeace) ia caaacia/o? aeaoieneeaoe?th i?aai?cio a?ae a?eueii?aaeeeaeueieo i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a, ui coiiaeth? iaiao?aei?noue aeeth/aiiy a eiiieaenia e?eoaaiiy oeei oai?ei aioea?iienaio?a, aioeieneaeaio?a, iaia?aiii?ioaeoi??a. 5. A oiene/i?e ? oa?i?iaeuei?e noaae?yo ia?eoii?oo ?icaeaa?oueny ?aaeoe?y aiaeioieneeico ca oeiii "no?ano", yea noi?iaiaeaeo?oueny iaeiie/aiiyi aaeeei? e?eueeino? oiene/ieo i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a a e?ia? oai?eo. Caa?aaeaiiy a i?neyiia?aoe?eiiio ia??iae? aenieiai ??aiy eaeeioeeoa?iiai ?iaeaeno ?ioieneeaoe??, iieaeoe na?aaeiuei? iane, i?iaeoeo?a ia?aeeniiai ieeneaiiy e?i?ae?a aai ?o ??cea ca?eueoaiiy na?ae/aoue i?i i?ia?anoaaiiy caiaeaiiy, aai aeieeiaiiy ai?eii-caiaeueieo oneeaaeiaiue, iia"ycaieo c iae?icii oeaiei. 6. A ?acoeueoao? eiiieaeniiai e?eoaaiiy ia?eoii?oo, ui aeeth/a? ? aioa?ini?aoe?th aioa?inaaeai, aeyaeaia aeinoia??ia oaiaeaioe?y a?aeiiaeaiiy iieaciee?a ??aiy ia?aeeniiai ieeneaiiy e?i?ae?a, AOO, AAeO, noie ioeeaioeae?a. 7. A?iioii?/iee aioenaioe/iee ?ic/ei, aaaaeaiee a /a?aaio ii?iaeieio, aaeueio? oaco aenoaeaoe?? i?e ia?eoii?o?, noeioeth? i?ioean ?aci?aoe??, ni?eyth/e ?aa?ano caiaeaiiy a i/a?aaei?. Canoinoaaiiy a?iioii?/iiai aioenaioe/iiai ?ic/eio a eiiieaeniiio e?eoaaii? ia?eoii?oo iie?auo? ?acoeueoaoe e?eoaaiiy, ciaioo? e?euee?noue aioo??oiuei/a?aaieo oneeaaeiaiue. 8. E?aii?ei?aai?/iee iie?ia? iie?iaoeeneeienai ? aenieiaoaeoeaiei ? ye aioa?ini?aaio, ? ye iao?eoey aeey ?iiia?e?caoe?? e?ea?nueeeo cania?a. Eiiieaeni? i?aia?aoe ia eiai iniia? - ?iinaaio oa ?iinaeei?o ? iiooaeieie aioei?e?iaieie i?aia?aoaie oe?ieiai niaeo?a ae?? c i?ieiiaiaaiei aoaeoii a i?io?eaeoeoe? iaaii?iiy i?neyiia?aoe?eii? ?aie oa e?eoaaii? aioo??oiuei/a?aaieo aanoean?a. 9. A??ciei oneeaaeiaiiyi ia?eoii?oo ? eiai i?ia?anoaaiiy, aaaio?aoe?y, aioo??oiuei/a?aai? aanoeane. Cai?iiiiiaaiee niin?a e?eoaaiiy aioo??oiuei/a?aaieo aanoean?a c canoinoaaiiyi ?iinaeei?oo oa ?iinaaioo i?inoee, ao?aaiaoe/iee, ia iia"ycaiee c ?eceeii oneeaaeiaiue. Aioei?e?iai? i?aia?aoe i?oacie oa aaioai?oeei, ?iiia?e?ciaai? ia iie?iaoeeneeienai?, iathoue i?ieiiaiaaio ae?th, ui caaacia/o? ?o aenieo eiioeaio?aoe?th o aiaieu? caiaeaiiy. 10. Oaeoi?aie i?aeaeuaiiai ?eceeo aeieeiaiiy iaaii?iiy i?neyiia?aoe?eii? ?aie o oai?eo ia ia?eoii?o ?: ii?ooaiiy anaioeee, iaee??iiy, o?eaaea caeaaethaaiiy ?aie ?aii?icoe?thaa/ai, o?eaae? iia?aoe??, oeoe?iaee ae?aaao. Iaaii?iiy i?neyiia?aoe?eii? ?aie o oai?eo ia ai?eiee ia?eoii?o aac canoinoaaiiy oe?eani?yiiaaieo iaoiae?a i?io?eaeoeee a?aei?/aii o 34,5 % oai?eo, a oa?i?iaeuei?e noaae?? ia?eoii?oo - o 45,8%. I?e aeei?enoaii? eiiieaeno caoiae?a, ui aeeth/athoue ? aie?eaoe?ei? ni?aaioe (iie?ni?a, ?iinaaio, ?iinaeei?o oa ?i.), iaaii?iiy i?neyiia?aoe?eii? ?aie ciaioeeeny a 2,4 ?ace ? noaiiaeee 14,3%. 11. Eaia?inoii?y c i?ia?aiiaaiith naiaoe??th /a?aaii? ii?iaeieie a ii?aeiaii? c aioa?ini?aoe??th aioa?inaaeai ? aoaeoeaiei iaoiaeii eiiieaeniiai e?eoaaiiy oyaeeeo oi?i ia?eoii?oo. Eaoaeuei?noue a oe?e a?oi? oai?eo cieceeany c 51,3 aei 36,5%. 12. Iniiaiith i?e/eiith eaoaeueiiai e?ioey o oai?eo ia ia?eoii?o ? ai?eii-naioe/i? oneeaaeiaiiy oa iie?i?aaiia iaaeinoaoi?noue, ui niinoa??aaeany o 84,3% iiia?eeo oai?eo. A ?acoeueoao? canoinoaaiiy a eiiieaeniiio e?eoaaii? eiia?iiaaii? eaca?ii? oa?ai??, aioa?ini?aoe??, a?iioii?/iiai aioenaioe/iiai ?ic/eio aeey i?iieaaiiy /a?aaii? ii?iaeieie, ni?aoe?eieo i?aia?ao?a caaaeueia eaoaeuei?noue cieceeany a 1,3 ?ace, i?e caiouaieo oi?iao ia?eoii?oo - a 1,4 ?ace. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe??. 1. Aeia?aeiee c iaaee/ii? aeiiiiiae ia aeiaini?oaeueiiio aoai? / Cicoey ?.N., Aa?oeai?a A.A., Aaeaiiae/ O.A., Aieioei A.I., Aaiaeaea O.?., Ai?iae/aiei E.?., Aeiaaaethe ?.I, Eiaaeaanueeee A.A., Einothe I.E., Eo?aoia I.A., Ianoeae A.A., Iaiceinueea E.A., Iie?uoe E.E., ?iuei A.A., Nieieia I.O., Ooo/aiei I.?., Ooaeioei A.E., Aao?i A.I., A?eyaaa I.I., Neiiaoeueeee A.?. – E.: Caei?ia’y, 1998. – 198n. 2. 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Canoinoaaiiy ni?aoe?eieo i?aia?ao?a o eiiieaeniiio e?eoaaii? ia?eoii?oo // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ii cae?i/aieo oa ia?ao?aeieo IAe? ca 1990-1996 ?iee .– E. - 1997. – N. 53 - 54. 47. Aaeyaaa I.A. Aeeaaiinoeea ia?eoiieoa e iaeioi?ua aniaeou aai ea/aiey // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ii cae?i/aieo oa ia?ao?aeieo IAe? ca 1990 -1996 ?iee. - E. - 1997. – N. 49 - 51. 48. ?aaec?oianueeee A.I., A?ey?aa I.I., Iaiaeaeue I.A., A?ey?a A.A. Iaoiaaiaoe/ia ei?aeoe?y iieaciee?a ?ioi?oaoo i?e ia?eoii?o? // Iaoa??aee i?aeia?iaeii? iaoeiai? eiio. “Aeooaeuei? ieoaiiy no/anii? o??o?a??”. – Oaeai?iae. - 1997. – N. 204. 49. A?ey?aa I.I., Naae/ I.?, A?ey?a A.A. ?acoeueoaoe e?eoaaiiy ia?eoii?oo ca aeiiiiiaith iiaeo ni?aoe?eieo i?aia?ao?a // Iaoa??aee i?aeia?iaeii? iaoeiai? eiio. “Aeooaeuei? ieoaiiy no/anii? o??o?a??”. – Oaeai?iae. - 1997. – N. 203. 50. ?aaeceoianeee A.I.,.Aeeoeie?ia A.A, Iieeaeueei I.E.,Aaeyaaa I.A. Aeeyiea aeiioiie/aneiai ?anoai?a aioenaioeea ia iacioaeee a?thoeiu a yenia?eiaioa i?e ia?eoiieoa // Nai?iee iao/iuo ?aaio, iinayu. 75-eaoeth eaoaae?u oe?o?aee EIAII IC Oe?aeiu “Iiaua oaoiieiaee a oe?o?aee”. – E.: A?o A?aoee. - 1997. – N. 173 - 174. 51. ?aaeceoianeee A.I., Aaeyaaa I.A., Iieeaeueei I.E., Iieeaeueei E.A., Aaeyaa A.A. Eniieueciaaiea aeiioiie/aneiai ?anoai?a aioenaioeea a eiiieaeniii ea/aiee ia?eoiieoa // Nai?iee iao/iuo ?aaio, iinayu. 75-eaoeth eaoaae?u oe?o?aee EIAII IC Oe?aeiu “Iiaua oaoiieiaee a oe?o?aee”. – E.: A?o A?aoee. - 1997. – N. 172 - 173. 52. Aaeyaaa I.A. Iaoiaaiaoe/aneea aniaeou i?ioeeaeoeee iaaiiaiey iia?aoeeiiiie ?aiu o aieueiuo ia?eoiieoii // Nai?iee iao/iuo ?aaio, iinayu. 75-eaoeth eaoaae?u oe?o?aee EIAII IC Oe?aeiu. “Iiaua oaoiieiaee a oe?o?aee”. – E.: A?o A?aoee. - 1997. – N. 156 - 157. 53. A?ey?aa I.I., Ei?ieueia TH.I. Aeeiai?ea iieaeoe na?aaeiuei? iane (INI) o oai?eo ?iciianthaeaeaiei ia?eoii?oii // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ?i. I.E. Ooieea. – E. - 1998. – Aei.7, ei.2. – N. 4 - 6. 54. Neo?aoianueeee I.O., A?ey?aa I.I., Noaia/iaa O.?., Ei?oey A.I., Iaiaeaeue I.A., I?eeaiiaa ?.A. Aoi?eiia ?ioiia iaaeinoaoi?noue i?e ia?eoii?o? oa ?? ei?aeoe?y // Ca??iee iaoeiaeo i?aoeue ni?a?ia?oiee?a EIAII ?i. I.E. Ooieea. – E. - 1998. – Aei.7, ei.2. – N. 221 - 226. 55. Aaeyaaa I.A., Iaiueeianeay I.I. ?ieue yia?aaoe/aneiai iaiaia eeioieae-iie oeaie a oi?ie?iaaiee eiioiieiae/aneie ?aaeoeaiinoe e ?acenoaioiinoe i?aaiecia // Ca??iee ?ia?o iaoeiai? eiio.“Aeooaeuei? i?iaeaie iaie?aaoiaaiaoi-a?e?a?ii? oa noaeeiii? o??o?a??” – E.: Ee?i. o??o?a?y. - 1998. – N. 343 - 346. 56. Aaeyaaa I.A. Ae?aie?iaaiea eeoa/ieea i?e ia?eoiieoa // Ca??iee ?ia?o iaoeiai? eiio. “Aeooaeuei? i?iaeaie iaie?aaoiaaiaoia?e?a?ii? oa noaeeiii? o??o?a??” – E.: Ee?i. o??o?a?y. - 1998. – N.342 - 343. 57. A?ey?aa I.I. ?ieue ia?aeeniiai ieeneaiiy e?i?ae?a a iaoiaaiac? ia?eoii?oo // Nai?iee ?aaio iao/ii - i?aeo. eiio., iinayuaiiie 15-eaoeth eaoaae?u oe?o?ae/aneeo aieaciae “Aeooaeueiua aii?inu iaioeiaeiie oe?o?aee i?aaiia a?thoiie iieinoe”. – Oa?ueeia. – 1998. – N. 73 - 74. 58. Aaeyaaa I.A. Eio?aiia?aoeeiiiue “eaaaae” a?thoiie iieinoe i?e ?ani?ino?aiaiiii ia?eoiieoa // Ca??iee iaoeiaeo ?ia?o ?? Eiia?ano o??o?a?a Oe?a?ie. – Ee?a – Aeiiaoeuee: “Ee?i?/ia o??o?a?y”, 1998. – N. 8 - 9. 59. Oaa/aiei TH.I., Neeiyeiaa E.A., Aaeyaaa I.A. I?aia?aou ni?aoeeiiii-aeaoieneeaoeeiiiiai aeaenoaey ia iniiaa ii?enouo e?aiieei?aaie/aneeo iao?eoe // Iaoa?eaeu ???-e Aaei?onneie iao/ii - i?aeo. eiio. “Yooa?aioiua e oeceei-oeie/aneea iaoiaeu oa?aiee”. – Iiaeeaa. - 1998. – N. 236 - 250. Aiioaoe?y A?ey?aa I.I. Eiiieaenia e?eoaaiiy ia?eoii?oo oa i?io?eaeoeea eiai oneeaaeiaiue (aenia?eiaoaeueii-ee?i?/ia aeine?aeaeaiiy). - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.03 - o??o?a?y.- Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I.E. Ooieea IIC Oe?a?ie, Ee?a, 1999. Aeena?oaoe?y i?enay/aia e?eoaaiith ?iciianthaeaeaiiai ia?eoii?oo, eiai oneeaaeiaiue oa ?o i?io?eaeoeoe? ?c canoinoaaiiyi o?i?i- oa a?ini?aoe?eieo i?aia?ao?a. I?iaaaeaii ianoaaeaiiy 435 oai?eo ia ?iceeoee oa caaaeueiee ia?eoii?o ??ciiai aaiaco. Cai?iiiiiaaia eeaneo?eaoe?y ia?eoii?oo oa eiai oneeaaeiaiue. A eiiieaeniiio e?eoaaii? ia?eoii?oo aeei?enoai? aeoeai? iaoiaee e?eoaaiiy - eaia?inoii?y c i?ia?aiiaaieie naiaoe?yie /a?aaii? ii?iaeieie. Iaa?oioiaaii ? ai?iaaaeaeaii a i?aeoeeo niin?a e?eoaaiiy ia?eoii?oo, yeee a?oioo?oueny ia o?ceei-o?i?/iiio caeii? iniino. Canoiniaaia eiia?iiaaia eaca?ia oa?ai?y, aioa?ini?aoe?y aioa?inaaeai. Aea/ai? aia?aaoe/i? i?ioeane o oai?eo ia ia?eoii?o (AOO, AIO, AAeO, IIE, INI, eaoaeaca, iiei/ia eeneioa), ??aaiue yeeo caeaaeeoue a?ae nooiaiy aiaeioieneeico. I?aeoaa?aeaeaii, ui o oai?eo ia?eoii?oii ?icaeaa?oueny aoi?eiiee ?ioiiaeao?oeeo. Aecia/ai? oaeoi?e ?eceeo aeieeiaiiy iaaii?iiy iia?aoe?eii? ?aie. Aia?oa aea/aii aeanoeaino? oa aoaeoeai?noue noai?aiiai i?ioei?e?iaiiai i?aia?aoo i?ieiiaiaaii? aioei?e?iaii? ae?? "?iinaeei?o", yeee neeaaea?oueny c iie?iaoeeneeienaia oa ?iiia?e?ciaaieo ia iueiio i?oacieo ? aeeiaeneaeo. Cai?iiiiiaaiee niin?a i?io?eaeoeee iaaii?iiy i?neyiia?aoe?eii? ?aie. E?euee?noue iaaii?iue iia?aoe?eii? ?aie o oai?eo ia ia?eoii?o cieceeany a 2,4 ?ace ? noaiiaeea 14,3%. I?e i?noeaaiio ia?eoii?o? eaoaeuei?noue neeaea 1,7%, aeeoociiio – 3,2%, ?iceeoiio ? caaaeueiiio - 26,8%. A ?aaeoeai?e noaae?? ?iceeoiai oa caaaeueiiai ia?eoii?oo eaoaeuei?noue neeaea 9,1%, a oiene/i?e ? oa?i?iaeuei?e - 33,9%. Caaaeueia eaoaeuei?noue i?e ia?eoii?o? neeaea 9,86%. Ca inoaii? 6 ?ie?a a ii??aiyii? c ia??iaeii 1986 - 1991 ?.?. eaoaeuei?noue cieceeany a 1,3 ?ace. Eeth/ia? neiaa: ia?eoii?o, eaia?inoii?y, iniin, ?ioiiaeao?oeeo, ni?aaioe, oneeaaeiaiiy, i?io?eaeoeea. THE SUMMARY Aelayeva I.A. Nomplex treatment of the peritonitis and preventive maintenance of it`s complications. Ohe manuscript. Dissertation on competition of a scientific degree of the doctor of medical sciences on a speciality 14.01.03 - surgery. - Kiev medical academy of postgraduate education named after P.L. Shupyk. Ministry of Health of Ukraine, Kiev, 1999. The dissertation is devoted to treatment of the diffuse peritonitis, it`s complications and it`s preventive maintenance with application of chemo- and biosorption preparations The inspection 435 patients of the diffuse peritonitis of the various genesis is carried out. The peritonitis classification and it`s complications is offered. In complex peritonit treatment the active methods of treatment - laparostomy with programm sanations of the abdominal cavity are used. Is developed and putted into practis the method of peritonitis treatment based on physic-chemycal law of osmos. The combined laser therapies , the enterosorption therapy by an enterosgel have been used The power processes, which level depends on a degree of endotoxicosis at the patients having the peritonitis (AOPh, AIPh, ADPh, POL, IMI, catalasa , lactic acid) are investigated. The factors of risk of occurrence of the suppuration of an operational wound are determined. It is created an effective antimicrobic preparation of the prolonged action “Imosdinit”, consisting from polymethylsiloxane and immobilized on it Nitasole, Dymexide,. The way of preventive maintenance of the suppuration of a postoperative wound is offered. The number of the suppuration of an operational wound has decreased in 2,4 times and has made 14,3 %. At local peritonitis the lethality has made 1,7 %, diffuse - 3,2 %, widespread and general - 26,8%. In a reactive stage of the peritonitis lethality has made 9,1 %, in toxic and terminal - 33,9%. General lethality at peritonitis has made 9,86%. In comparsion with a period 1986-1991 yrs. lethality has decreased in 1,3 times. Key words: peritonitis, laparastomy, osmos, immunodeficiency, biosorption preparations, complication, preventive maintenance. AIIIOAOeEss Aaeyaaa I.A. Eiiieaeniia ea/aiea ia?eoiieoa e i?ioeeaeoeea aai ineiaeiaiee (yenia?eiaioaeueii-eeeie/aneia enneaaeiaaiea). - ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie aeieoi?a iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.03 – oe?o?aey. – Eeaaneay iaaeeoeeineay aeaaeaiey iineaaeeieiiiiai ia?aciaaiey ei. I.E. Ooieea IC Oe?aeiu, Eeaa, 1999. Aeenna?oaoeey iinayuaia ea/aieth ?aceeoiai e iauaai ia?eoiieoa, aai ineiaeiaiee e eo i?ioeeaeoeea n i?eiaiaieai oeiei- e aeini?aoeeiiiuo i?aia?aoia iiaiai iieieaiey. Oeaeue enneaaeiaaiey: iiauneoue yooaeoeaiinoue ea/aiey aieueiuo ia?eoiieoii, nieceoue /enei ineiaeiaiee e iineaiia?aoeeiiioth eaoaeueiinoue. Aeey aeinoeaeaiey oeaee ?aoaii ?yae caaea/: eco/aiu i?e/eiu iaoaeiaeaoai?eoaeueiuo ?acoeueoaoia ea/aiey aieueiuo ia?eoiieoii, ineiaeiaiey, i?e/eiu eaoaeueiuo enoiaeia. A ia?eiae n 1992 ii 1997 a. a. i?iiia?e?iaaii 6722 aieueiuo n ino?uie caaieaaaieyie i?aaiia a?thoiie iieinoe, ia?eoiieo iaaethaeaeny o 1723 (25,63%) aieueiuo. Ianoiue ia?eoiieo aeeaaiinoe?iaai o 624 (36,22%) aieueiuo, ianoii-ioa?aie/aiiue – o 235 (13,64%), aeeooociue – o 319 (18,51%), ?aceeoie – o 341 (19,79%), iauee – o 204 (11,84%). Iaeaieaa oyaeaeua oi?iu ia?eoiieoa (?aceeoie e iauee) iaaethaeaeenue o 545 aieueiuo. ?aaeoeaiay noaaeey ia?eoiieoa ioia/aia o 176 (31,5%) aieueiuo, oiene/aneay – o 251 (46,8%), oa?ieiaeueiay – o 118 (21,7%)). A iniiao enneaaeiaaiey iieiaeai iiuo ea/aiey 435 aieueiuo ?aceeoui e iauei ia?eoiieoii. N ?aaeoeaiie noaaeeae ia?eoiieoa auei 66 aieueiuo, oiene/aneie – 251, oa?ieiaeueiie – 118. Ia iniiaaiee aeaiiuo aeioeie/aneeo enneaaeiaaiee nuai?ioee e?iae aieueiuo ?aceeoui e iauei ia?eoiieoii, iieacaii, /oi ino?ue ?ani?ino?aiaiiue ia?eoiieo ii naiae iaoiaaiaoe/aneie nouiinoe yaeyaony oaciui i?ioeannii e nii?iaiaeaeaaony aeiiene/iuie ia?ooaieyie a oeaiyo. A e?iae nieaeaaony o?iaaiue AOO e AAeO, iiauoaaony o?iaaiue iiei/iie eeneiou e aeoeaiinoue aioeieneaeaioiiai oa?iaioa eaoaeacu. A e?iae iaeaieeaathony i?iaeoeou IIE, iieeiaioeaeu n n?aaeiae iieaeoey?iie iannie e eo o?iaaiue caaeneo io noaiaie yiaeioieneeica. A yenia?eiaioa eco/aia ?ieue ianiaoeeoe/aneeo iaoaieciia yia?aiiaiaia a oi?ie?iaaiee aoi?e/iiai eiioiiaeaoeoeeoa iooai aaaaeaiey aeeaioiui aioeoeeoio?iiieneaeaciie nuai?ioee (AOeOIN), n oeo?ii i?aoeeieoe?othueo aioeoae 1:8, 1:64, a aeica 0,2 ie ia 100 a iannu aeeaioiiai ia iaeii aaaaeaiea. Enneaaeiaaiea i?iaaaeaii ia 235 e?unao iannie 170 – 220 a. Eco/aii aeeyiea AOeOIN ia i?ioeannu yia?aiiaania/aiey eeaoie eeioieaeiie oeaie. Aeieacaii, /oi oi?ie?iaaiea aoi?e/iiai eiioiiaeaoeoeeoa naycaii n ianiaoeeoe/aneeie iaoaieciaie yia?aiiaiaia eeioieaeiie oeaie. Aia?aua eco/aii a yenia?eiaioa e eeeieea yooaeoeaiinoue ni?aoeeiiiiai i?aia?aoa “eiinaeeieo” i?ieiiae?iaaiiiai aioeiee?iaiiai aeaenoaey, ninoiyuaai ec iieeiaoeeneeienaia – iao?eoea e eiiiaeeeciaaiiiai ia iai ieoaciea, aeeiaeneaea. Iieacaia aai aunieay yooaeoeaiinoue a ioiioaiee ay?iaiuo e aiay?iaiuo iaeeino?eaeeaeueiuo aicaoaeeoaeae. I?aaeeiaeai e aeaia ioeaiea i?eaeiaeueiiai niiniaa ea/aiey ia?eoiieoa, iniiaaiiiai ia oeceei-oeie/aneii yaeaiee iniina. A?aaeeaio iniioe/aneiai aeaaeaiey iaaeaeo aeiioiie/aneei aioenaioe/aneei ?anoai?ii, aaaaeaiiui a a?thoioth iieinoue e ainiaeaiiuie oeaiyie, iaoiaeyueieny a ninoiyiee aeia?iniee, iaania/eaaao oneeaiiia ananuaaiea aeeaeeinoe, /oi noeioee?oao ?aci?aoeeth, a oaeaea oi?iiceo yennoaeaoeeth e o?ainnoaeaoeeth a a?thoioth iieinoue. A ea/anoaa aioenaioeea eniieueciaaee oo?aoeeeei, oei?aaeneaeei, aeaeaiaoienei. Aeieacaii, /oi a oiene/aneie e oa?ieiaeueiie noaaeeyo ?acaeaaaony aoi?e/iue eiioiiaeaoeoeeo, eioi?ue i?iyaeyaony ia?ooaieai eae eeaoi/iiai, oae e aoii?aeueiiai eiioieoaoa. Iieacaia yooaeoeaiinoue eiiaeie?iaaiiie eaca?iie oa?aiee, yioa?ini?aoeee yioa?inaaeai e iaioeaeia oeiona a ei??aeoeee eiioiieiae/aneeo ia?ooaiee. I?iaaaeai n?aaieoaeueiue aiaeec ?acee/iiai oiaiiai iaoa?eaea. I?aaeeiaeaia eeanneoeeaoeey ia?eoiieoa e aai ineiaeiaiee. Ii?aaeaeaiu oaeoi?u ?enea aicieeiiaaiey iaaiiaiee iia?aoeeiiiie ?aiu. Iaoiaaiaoe/anee iainiiaai e i?aaeeiaeai niinia i?ioeeaeoeee iaaiiaiee iia?aoeeiiiie ?aiu e ea/aiey aioo?ea?thoiuo aanoeannia. ?ac?aaioaia e aiaae?aia a i?aeoeeo eaia?inoiiey n i?ia?aiie?iaaiiuie naiaoeeyie a?thoiie iieinoe. Iiaeoaa?aeaeaii ?acaeoea aeenaaeoa?eica o aieueiuo ia?eoiieoii e yooaeoeaiinoue ei??aeoeee aeenaeioe/aneeo ia?ooaiee i?eiaiaieai eaeoiaaeoa?eia a ni/aoaiee n yioa?inaaeai. Iaaiiaiea iia?aoeeiiiie ?aiu o aieueiuo aiieiui ia?eoiieoii aac oeaeaiai?aaeaiiuo iaoiaeia i?ioeeaeoeee ioia/aii o 34,5% neo/aaa. A oa?ieiaeueiie noaaeee ia?eoiieoa – o 45,8%. I?e eniieueciaaiee aiieeeaoeeiiiuo ni?aaioia iieeni?aa, eiinaaioa, eiinaeeieoa ioia/aii nieaeaiea iaaiiaiee iia?aoeeiiiie ?aiu a 2,4 ?aca e ninoaaeei 14,3% . I?e ianoiii ia?eoiieoa eaoaeueiinoue ninoaaeea 1,7%, aeeooociii – 3,2%, ?aceeoii e iauai – 26,8%. A ?aaeoeaiie noaaeee ?aceeoiai e iauaai ia?eoiieoa eaoaeueiinoue ninoaaeea 9,1%, a oiene/aneie e oa?ieiaeueiie – 33,9%. Iniiaiie i?e/eiie eaoaeueiuo enoiaeia yaeythony aiieii-naioe/aneea ineiaeiaiey e iieei?aaiiay iaaeinoaoi/iinoue, iaaethaeaaoeany o 84,3% aieueiuo. Iauay eaoaeueiinoue i?e ia?eoiieoa ninoaaeea 9,86%. Ca iineaaeiea 6 eao ii n?aaiaieth n ia?eiaeii 1986-1991 a. a. eaoaeueiinoue nieceeanue a 1,3 ?aca. Eeth/aaua neiaa: ia?eoiieo, eaia?inoiiey, iniin, eiioiiaeaoeoeeo, ni?aaiou, ineiaeiaiey, i?ioeeaeoeea.

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