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Комплексна ехо-радіонуклідна діагностика порушень гемодинаміки у хворих на міокардит: Автореф. дис… канд. мед. наук / О.А. Красюк, Укр. НДІ онкологі

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I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

OE?A?INUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO

IIEIEIA?? ? ?AAe?IEIA??

E?ANTHE Ieaenaiae? Aiaoie?eiae/

OAeE 616.127-002-005-073.75

EIIIEAENIA AOI-?AAe?IIOEE?AeIA Ae?AAIINOEEA

II?OOAIUe AAIIAeEIAI?EE O OAI?EO IA I?IEA?AeEO

14.01.23 – i?iiaiaaa ae?aaiinoeea, i?iiaiaaa oa?ai?y

A A O I ? A O A ? A O

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia o A?enueeiai-iaaee/iiio ?inoeooo?

Oe?a?inueei? a?enueeiai-iaaee/ii? aeaaeai??, Oe?a?inueeiio IAe?
ea?ae?ieia?? ?i.aeaae. I.Ae.No?aaeanea

Iaoeia? ea??aieee:

aeieoi? iaaee/ieo iaoe, i?ioani? Oeeaaieia Aiaoie?e Oeiio?eiae/-
i?ioani? eaoaae?e a?enueeiai? oieneeieia??, ?aae?ieia?? ? iaaee/iiai
caoenoo A?enueeiai-iaaee/iiai ?inoeoooo OAIA

aeieoi? iaaee/ieo iaoe, i?ioani? Ai?iieia Eaii?ae Aai?a?eiae/- ea??aiee
a?aeae?eaiiy na?oeaai? iaaeinoaoiino? Oe?a?inueeiai IAe?
ea?ae?ieia?? ?i.aeaae. I.Ae.No?aaeanea

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani? Oeoe?ia Aaeaioeia Aieiaeeie??aia –
aieiaiee iaoeiaee ni?a?ia?oiee, eiinoeueoaio a?aeae?eo ?aae?aoe?eii?
iieieia?? oa yaea?ii? iaaeeoeeie Oe?a?inueeiai IAe? iieieia?? oa
?aae?ieia?? IIC Oe?a?ie

aeieoi? iaaee/ieo iaoe, i?ioani? Neaaiia Aaeaioei Ieeieaeiae/
-i?ia?aeiee iaoeiaee ni?a?ia?oiee eaai?aoi??? ?aae?ieia?? IAe?
aiaeie?eiieia?? ? iai?io ?a/iaei ?i. A.I. Eii?na?aiea AII Oe?a?ie

I?ia?aeia onoaiiaa – Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe
?i.I.E.Ooieea (eaoaae?a iaaee/ii? ?aae?ieia??) IIC Oe?a?ie

Caoeno a?aeaoaeaoueny « 26 » eenoiiaaea 1998?. i 13 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.619.01 i?e Oe?a?inueeiio
iaoeiai-aeine?aeiiio ?inoeooo? iieieia?? oa ?aae?ieia?? IIC
Oe?a?ie (252022, i. Ee?a, aoe. Eiiiiiniaa, 33/43).

C aeena?oaoe??th iiaeia iciaeiieoeny a a?ae?ioaoe? Oe?a?inueeiai
iaoeiai-aeine?aeiiai ?inoeoooo iieieia?? oa ?aae?ieia?? IIC Oe?a?ie

(i. Ee?a, aoe. Eiiiiiniaa, 33/43).

Aaoi?aoa?ao ?ic?neaiee «25» aeiaoiy 1998?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe Aeeeai ?.I.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie.

Nai?/ania eiiieaenia ae?aaiinoeea oa aaeaeaaoia e?eoaaiiy i?iea?aeeoo,
ye iaeiioe?ai?oi? iaei?iia?iaaiii? iaoieia?? na?oeaaiai i`yco,
aeooaeuei? o ca`yceo c eiai aaaeeei ee?i?/iei ia?aa?aii oa iani?eyoeeaei
i?iaiicii (E.A.Iaoiaiei, 1981; TH.E.Iiaeeia e niaao.,
1985I.C.Caoa?/aiei, 1984; I.A.?eeyo ? ni?aaao., 1994, 1995; I.?.
Iaeaaa e niaao., 1982, 1983, 1997; I.N. Eaiaiaoeueeee ? ni?aaao.,
1998; J.B.O`Connel et al., 1984, 1994).

Neeaaei?noue oa aaaaoieiiiiiaioi?noue iaoiaaiaco iaaeinoaoiino?
e?iaiia?ao (IE) i?e oeeo caoai?thaaiiyo i?aeiinyoue ae??oaiiy cacia/aii?
i?iaeaie ia iaaeeei-a?ieia?/iee ??aaiue, ine?eueee ?aaeoe?y
aaiiaeeiai?ee ia caiaeueiee i?ioean oa ii?ooaiiy ianinii? ooieoe??
na?oeaaiai i`yco a?aeaoaa?oueny ca caeiiaie oe?e?nii? ooieoe?iiaeueii?
nenoaie (I.E.Oo?eaei ? ni?aaao., 1985; A.E.*acia, 1993; E.O.Iaeay, 1994,
1996; N.Aeae.Aieea ? ni?aaao., 1995; E.A.Ai?iieia ? ni?aaao., 1995;
?.N.*aeiai, 1995; K.Weber, D.Villarreal,1993; H.Feigenbaum,1996).

Caaaeueiiaeciaieie iaoiaeaie aeine?aeaeaiiy, ui aeicaieythoue
ia`?eoeaii ioe?ieoe aaiioee?eoeyoi?i? ?iceaaee aaeeeiai oa iaeiai e?e
e?iaiia?ao, ? ciiaeoaaiiy ii?iaeiei na?oey oa iaa?no?aeueieo noaeei a
eiiieaen? c aia?ia?ao??th (C.N.Oeaeaeiaa,1996).

Aiaeii/an, i?eoeeueieee ?ioa?aaioe?eii? ae?aaiinoeee ii?ooaiue
aaiiaeeiai?ee aeiooai? aeciaoe aacia?a/i? ia?aaaae ia?iaaceaieo niinia?a
ianoaaeaiiy oai?eo- aoiea?ae?ia?ao?? oa ?aae?iea?ae?ia?ao??
(A.A.Na?a??iei, 1991; O.I.Neaa/aiei, Ae.N.Ia/aa e niaao., 1991)
ia?oi/a?aiai, caaaeyee iiai?e a?aenooiino? aoaeue-yeeo oneeaaeiaiue i?e
aiaeia?/iiio ianyc? io?eiaii? ?ioi?iaoe??.

Iacaaaeath/e ia aeineoue oe?iea ai?iaaaeaeaiiy ?aae?iioee?aeieo oa
oeueo?acaoeiaeo aeine?aeaeaiue a oiiaao ea?ae?ieia?/ieo ee?i?e, a?aeii?
eeoa iiiaeeiie? iaoeia? ioae?eaoe??, ui i?enay/ai? ?o eiiieaeniiio
canoinoaaiith o oai?eo ia i?iea?aeeo (A.O.Oeeaaieia,1983;
I.C.Caoa?/aiei, 1984).

Iniiaiith i?e/eiith iaoooaaiiy oao?aoe?a aeniei/ooeeaei, caeaoiei
iaaeaoe ?ioaa?aeueio oa ?icae?eueio ioe?ieo aaiiaeeiai?ee ae?aaiinoe/iei
eiiieaenii ne?ae aeciaoe o?c?ieia?/io iaaaeaeaaoi?noue a?aeiieo iaoiaeee
?aae?iea?ae?ia?ao?? oa ?aae?ioee?eoeia?ao??. Iaiaeii/ania aecia/aiiy
ia?aiao??a ooieoe?? na?oey oa ia?eoa?e/iiai e?iaiia?ao oo?oaeith?
anoaiiaeaiiy aca?iica’yceo aeyaeaieo a?aeoeeaiue ? ia?aaeaa/a? aeaa-o?e
iine?aeiaieo aaaaeaiiy ?OI.

Onoiaiiy oeueiai iaaeie?eo noai?th? oiiae aeey ?ic?iaee niiniao
ia?iaaceaii? ?ioaa?aeueii? ioe?iee ii?ooaiue oeaio?aeueii? oa
ia?eoa?e/ii? aaiiaeeiai?ee o oai?eo ia i?iea?aeeo; aecia/eoe e?eoa???
ie?aieo aaiiaeeiai?/ieo oei?a oa noaae?e IE; aea/eoe iaoiaaiaoe/i? oa
eiiiainaoi?i? iaoai?cie oi?ioaaiiy neiae?iio IE oa eiio?iethaaoe
aoaeoeai?noue eiai e?eoaaiiy.

Aino?ioa i?iaeaie, iaiao?aei?noue ?? iaa?aeeeaaeiiai ae??oaiiy
iiaeeaeth?oueny ua e oei, ui cia/ia /anoeia oai?eo ia i?iea?aeeo-
aei?inea /anoeia ianaeaiiy i?aoeacaeaoiiai a?eo, eaae?o?eiaaia a
i?ioan?eiiio a?aeiioaii?. Iaaeaeue, aeoaea /anoi coneeey oao?aoe?a o
aeiaaio?eaaeiio i?ioean? e?eoaaiiy oa ?aaa?e?oaoe?? caiaeyoueny ia
i?aaoeue oe?ieei niaeo?ii a?aeaeaeaieo iane?aee?a, aae aei
?iaae?ae?caoe?? iaoe??io?a (TH.?.Iiaeeia, I.A.Nooeiaa, 1985;
O.?.Eiia?ia, 1991; ?.E. Anaoethe, 1995).

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie.

Aeena?oaoe?eia ?iaioa aeeiiaia ye o?aaiaio eiiieaenii? oaie IAe?
eaoaae?e a?enueeiai? oa?ai?? A?enueeiai-iaaee/iiai ?inoeoooo OAIA oa
a?aeae?eo na?oeaai? iaaeinoaoiino? Oe?a?inueeiai IAe? ea?ae?ieia??
?i.aeaae I.Ae.No?aaeanea AII Oe?a?ie «?ic?iaeoe iia? iaoiaaiaoe/ii
iaa?oioiaai? iaoiaee e?eoaaiiy oai?eo c o?ii?/iith na?oeaaith
iaaeinoaoi?noth ??ciiai aaiaco» ? aea?ae. ?a?no?aoe?? 0196 E 005233.

Iaoa aeine?aeaeaiiy. I?aeaeueoe aoaeoeai?noue ae?aaiinoeee ?iceaae?a
oeaio?aeueii?, ?io?aea?ae?aeueii? oa ?aa?iia?ii? (iiceiai?,
ea?ae?iii?oaeueii?, aaeeeiai ? iaeiai eiea e?iaiia?ao) aaiiaeeiai?ee o
oai?eo ia i?iea?aeeo /a?ac canoinoaaiiy eiiieaeniiai
aoi-?aae?iioee?aeiiai aeine?aeaeaiiy (neio?iiia ?aae?ioee?eoeia?ao?y,
aoiea?ae?ia?ao?y).

Caaaeaiiy aeine?aeaeaiiy:

1.?ic?iaeoe iaoiaeeeo neio?iiii? ?aae?ioee?eoeia?ao?? (N?OeA), aecia/eoe
?? i?eaeaoi?noue aeey ioe?iee ia`?iieo ? oaeaee?nieo iieaciee?a
oeaio?aeueii? oa ?aa?iia?ii? aaiiaeeiai?ee o oai?eo ia i?iea?aeeo.

2.Ia iniia? iieaciee?a N?OeA a?aeie?aieoe iciaee oei?a aaiioee?eoeyoe??
oa ?ic?iaeoe iiiia?aie aeey ?o aecia/aiiy.

3.Aeei?enoiaoth/e ?acoeueoaoe eiiieaeniiai aoi-?aae?iioee?aeiiai
aeine?aeaeaiiy, iiaeeaeoe oyaeaiiy i?i ?aae?caoe?th ie?aieo
eiiiainaoi?ii-i?enoinoaaeueieo iaoai?ci?a ia ??cieo noaae?yo noaiiaeaiiy
iaaeinoaoiino? e?iaiia?ao o oai?eo ia i?iea?aeeo.

4.Aea/eoe ca aeiiiiiaith N?OeA oa?aeoa? oa ae?aaeai?noue ii?ooaiue
iiceiaiai e?iaioieo o oai?eo ia i?iea?aeeo a caeaaeiino? a?ae noaae??
IE.

5.Aecia/eoe ?ieue oa i?noea aoiea?ae?ia?ao?? oa neio?iiii?
?aae?ioee?eoeia?ao?? a eiiieaen? ae?aaiinoe/ieo caoiae?a o oai?eo ia
caiaeueia a?aaeaiiy i?iea?aea, ui oneeaaeiaia iaaeinoaoi?noth
e?iaiia?ao.

Iaoeiaa iiaecia.

1.Aia?oa o a?o/eciyi?e i?aeoeoe? cai?iiiiiaaii ? ai?iaaaeaeaii iaoiaeeeo
neio?iiiiai ?aae?ioee?eoeia?ao?/iiai aeine?aeaeaiiy oeaio?aeueii? oa
?aa?iia?ii? aaiiaeeiai?ee. ?? aeei?enoaiiy aeicaieeei ia’?eoeaii oa
aaeaeaaoii ioe?ithaaoe ?iceaaee oeaio?aeueiiai ? ?aa?iia?iiai e?iaiia?ao
caaaeyee neio?iii?e ?a?no?aoe?? a?aeiia?aeieo ia?aiao??a a iaeei ? oie
aea /an, a iaeiaeiaeo o?c?ieia?/ieo oiiaao

2.Ca aeiiiiiaith N?OeA aecia/aii iayai?noue, e??i a?ia?- oa
a?iie?iaoe/iiai, ia?aaeienaeueieo oei?a aaiiaeeiai?ee, aeey yeeo ca oiia
ii?iaeueieo iieaciee?a caaaeueiiai ia?eoa?e/iiai iii?o i?eoaiaii?
i?aeaeuaiee (?-ia?aaeienaeueiee oei) aai cieaeaiee (?? ia?aaeienaeueiee
oei) oaeeeiiee ia`?i.

3.Aia?oa ca aeiiiiiaith ia’?eoeaiiai ?aae?iioee?aeiiai iaoiaeo
aeine?aeaeaiiy (neio?iiia ?aae?ioee?eoeia?ao?y) aeiaaaeaii iayai?noue
?iceaae?a oea?aa?aeueiiai ? ea?ae?iii?oaeueiiai e?iaiia?ao o oai?eo ia
i?iea?aeeo, ui oneeaaeiaiee IE.

4.Ia iniia? ?acoeueoao?a eiiieaeniiai aoi-?aae?iioee?aeiiai
aeine?aeaeaiiy iiaeeaeaii oyaeaiiy i?i aeaye? iaoiaaiaoe/i? aniaeoe
oi?ioaaiiy neiae?iio iaaeinoaoiino? e?iaiia?ao o oai?eo ia i?iea?aeeo;
aecia/ai? iniaeeaino? ?aae?caoe?? eiiianaoi?ii-i?enoinoaaeueieo
iaoai?ci?a i?e ??cieo oeiao aaiioee?eoeyoe?? oa noaae?yo IE.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a.

1.Cai?iiiiiaaia iaoiaeeea neio?iiii? ?aae?ioee?eoeia?ao??, yea aeicaiey?
io?eiaoe ia’?eoeaio ?ioi?iaoe?th i?i noai oeaio?aeueii? ? ?aa?iia?ii?
aaiiaeeiai?ee i?ioyaii iaeiiai aeine?aeaeaiiy, noai?th? oiiae aeey
aeaie?aoiiai ciaioaiiy i?iiaiaaiai iaaaioaaeaiiy oa o?eaaeino?
ianoaaeaiiy oai?eo.

2.?ic?iaeaii iaoeiai iaa?oioiaaiee aeai?eoi canoinoaaiiy
aoiea?ae?ia?ao?? oa neio?iiii? ?aae?ioee?eoeia?ao??? a eiiieaeniiio
ianoaaeaii? oai?eo ia i?iea?aeeo.

3.Ia iniia? noaoenoe/ii aeinoaoiuei? e?eueeino? niinoa?aaeaiue aaoi?ii
/?oei aecia/ai? ?aae?iioee?aei? e?eoa??? noaae?e IE oa oei?a
aaiioee?eoeyoe??. Inoaii? aeeeaaeai? o aeaeyae? c?o/ieo aeey
iianyeaeaiiiai aeei?enoaiiy iiiia?ai.

4.I?iaaaeai? iaoeia? aeine?aeaeaiiy ia?aeiieeai aeiaiaeyoue
aeioe?euei?noue ?ioaa?aeueii? ioe?iee ?iceaae?a oeaio?aeueii? oa
ia?eoa?e/ii? aaiiaeeiai?ee o oai?eo ia i?iea?aeeo. Eeoa ca oeeo oiia
noa? iiaeeeaei ia?aiiy aaeaeaaoiiai iaoiaaiaoe/iiai e?eoaaiiy, ioe?iea
eiai aoaeoeaiino?, aecia/aiiy nooiaiy iai?aoeacaeaoiino?
(?iaae?aeiino?) iaoe??io?a.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy a i?aeoeeo.

?acoeueoaoe aeine?aeaeaiiy ai?iaaaeaeai? a i?aeoe/io ae?yeuei?noue
a?aeae?eaiiy ?aae?iioee?aeii? ae?aaiinoeee Aieiaiiai a?enueeiaiai
ee?i?/iiai aini?oaeth II Oe?a?ie, eaai?aoi??? ?aae?iioee?aeieo iaoiae?a
aeine?aeaeaiiy iaoeiai-aeine?aeiiai ?inoeoooo ?i.aeaae. I.Ae.
No?aaeanea, ?aae?ieia?/iiai a?aeae?eaiiy *a?i?a?anueei? iaeanii?
e?ea?i?.

Iniiai? iieiaeaiiy ?iaioe aeei?enoiaothoueny a iaa/aeueiiio i?ioean? ia
eaoaae?? a?enueeiai? oa?ai?? A?enueeiai-iaaee/iiai ?inoeoooo
Oe?a?inueei? A?enueeiai-iaaee/ii? aeaaeai??.

Iniaenoee aianie caeiaoaa/a:

Aaoi?ii ?ic?iaeaii ? ai?iaaaeaeaii niin?a neio?iiii?
?aae?ioee?eoeia?ao??, ui aeicaiey? io?eiaoe ia’?eoeaio ?ioi?iaoe?th i?i
noai oeaio?aeueii? ? ?aa?iia?ii? aaiiaeeiai?ee i?ioyaii iaeiiai
aeine?aeaeaiiy, ciaioeoe i?iiaiaaa iaaaioaaeaiiy oa o?eaae?noue
ianoaaeaiiy oai?iai aaeai?

Iniaenoi aeeiiai? an? aoiea?ae?ia?ao?/i? aeine?aeaeaiiy, ?ioa?i?aoiaai?
?acoeueoaoe ?aae?iioee?aeieo aeine?aeaeaiue, ioe?iai? ye?ni? oa
ia/eneai? e?euee?ni? iieacieee, ui oa?aeoa?ecothoue noai oeaio?aeueii?,
?io?aea?ae?aeueii? oa ?aa?iia?ii? aaiiaeeiai?ee. Aea/aii aeaye? aniaeoe
iaoai?cio ?icaeoeo ii?ooaiue aaiioee?eoeyoe?? o oai?eo ia i?iea?aeeo,
oneeaaeiaiee iaaeinoaoi?noth e?iaiia?ao; ?ic?iaeaii iiiia?aio aecia/aiiy
oei?a aaiioee?eoeyoe?? ca ?acoeueoaoaie N?OeA; ?ic?iaeaii iaoeiai
iaa?oioiaaiee aeai?eoi canoinoaaiiy neio?iiii? ?aae?ioee?eoeia?ao?? a
eiiieaeniiio ianoaaeaii? oai?eo ia i?iea?aeeo ?c iaaeinoaoi?noth
e?iaiia?ao.

I?aeaioiaeaii aei ae?oeo 3 noaoo?, 7 oac aeiiia?aeae.

Ai?iaaoe?y ?iaioe.

Iniiai? iieiaeaiiy aeena?oaoe?? i?aaenoaaeai? o aeaeyae? aeiiia?ae? ?
iaaiai?ai? ia: Oe?a?inueeiio eiia?an? ?aae?ieia?a Oe?.’95 ( i.Ee?a,
1995?.); iaoeiai-i?aeoe/ieo eiioa?aioe?yo: «Nia?aiaiiua aniaeou
aiaiiie iaaeeoeeiu» ( i.Ee?a, 1995?.); «Aeooaeuei? i?iaeaie
a?enueeiai? iaaeeoeeie» (i.Ee?a, 1995?.); «I?iaeaiu aiaiiiai
cae?aaiio?aiaiey e iooe aai ?aoi?ie?iaaiey»( i.Ee?a, 1996?.); «I?iaeaiu
iaaeeoeeineiai iaania/aiey aiaiiineoaeaueo, i?iaeeaathueo ia
?aaeeiaeoeaii caa?yci?iiuo oa??eoi?eyo» (i.??i?iue, 1997?.); «I?iaeaiu
aiaiiiai cae?aaiio?aiaiey e iooe aai ?aoi?ie?iaaiey» (i.Ee?a, 1998?.) .

?iaioa i?ieoea ai?iaaoe?th ia ni?eueiiio can?aeaii? eaoaae?
a?enueeiai? oa?ai?? A?enueeiai – iaaee/iiai ?inoeoooo Oe?a?inueei?
a?enueeiai – iaaee/ii? aeaaeai??, aini?oaeueii? oa?ai?? IIO, eaai?aoi???
?aae?iioee?aeieo iaoiae?a aeine?aeaeaiiy ? a?aeae?eaiiy na?oeaai?
iaaeinoaoiino? Oe?a?inueeiai IAe? ea?ae?ieia?? ?i. aeaae.
I.Ae.No?aaeanea, ?aae?ieia?/iiai a?aeae?eaiiy AAEA, eaai?aoi???
?aae?aoe?eii? iaaeeoeeie a?aeae?eo iaaeeei-i?io?eaeoe/ieo aeenoeeie?i
AI? OAIA, aenia?oi?e ?aae? i?e niaoe?ae?ciaai?e a/ai?e ?aae?
Oe?a?inueeiai IAe? iieieia?? oa ?aae?ieia?? Ae 26.619.01.

Ioae?eaoe??.

?acoeueoaoe iaoeiaeo aeine?aeaeaiue aeeeaaeaii a 10 ioae?eaoe?yo: 3
noaooyo, 7 oacao aeiiia?aeae.

No?oeoo?a ? ianya ?iaioe.

Aeena?oaoe?y i?noeoue anooi, iaeyae iaoeiai? e?oa?aoo?e, o?e ?icae?ee
aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiaee, i?aeoe/i? ?aeiiaiaeaoe??,
nienie aeei?enoaieo iaoeiaeo aeaea?ae (225 iaeiaioaaiue). ?iaioa
aeeeaaeaia ia 171 noi??ioe? iaoeiiieniiai oaenoo, aeeth/a? 26 oaaeeoe?,
18 ?ethno?aoe?e.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee ? iaoiaee aeine?aeaeaiiy

O 167 /ieia?e?a a?eii a?ae 18 aei 58 ?ie?a, oai?eo ia i?iea?aeeo,
oneeaaeiaiee IE, aea/ai? iieacieee oeaio?aeueii?, aioo??oiueina?oeaai?,
?aa?iia?ii? (aaeeeiai ? iaeiai eiea e?iaiia?ao, oea?aa?aeueii?,
ea?ae?iii?oaeueii?) aaiiaeeiai?ee. Ia iniia? aeaoaeueiiai aea/aiiy
ee?i?/ieo aeaieo on? oai?? aoee ?iciiae?eai? ia a?oie a caeaaeiino? a?ae
noaae?? IE ca eeaneo?eaoe??th I.Ae.No?aaeanei- A.O.Aaneeaiei (oaae.1).

Oaaeeoey 1

?iciiae?e oai?eo ia i?iea?aeeo ca a?eii oa noaae??th IE

A?e

(?iee) IE I co.

n=72 IE II A co.

n=69 IE IIA- III co.

n=26

Aan. % Aan. % Aan. %

Aei 20

21-30

31-40

Noa?o? 40 14

39

16

3 19,4

54,2

22,2

4,2 12

28

25

4 17,4

40,6

36,2

5,8 1

4

14

7 3,8

15,5

53,8

26,9

Na?aaei?e a?e

(I±m)

26,0±2,6

24,3±3,0

36,0±2,7

Aei eiio?ieueii? a?oie oa?eoei 20 /ieia?e?a a?aeiia?aeiiai aei a?oie
niinoa?aaeaiiy a?eo.

On? oai?? i?ioiaeeee eiiieaenia caaaeueiiee?i?/ia oa niaoe?aeueia
ianoaaeaiiy ? e?eoaaiiy ia aac? Aieiaiiai a?enueeiaiai ee?i?/iiai
aini?oaeth II Oe?a?ie ? iaoeiai-aeine?aeiiai ?inoeoooo ea?ae?ieia??
?i. aeaae. I.Ae.No?aaeanea.

Ee?i?/iee ae?aaiic i?iea?aeeoo anoaiiaethaaee ia iniia? aeaieo
ee?i?/iiai, eaai?aoi?iiai ? ?ino?oiaioaeueiiai iaoiae?a aeine?aeaeaiiy c
a?aooaaiiyi e?eoa???a ae?aaiinoeee i?iea?aeeo?a Iueth – Ei?enueei?
Anioe?aoe?? ea?ae?ieia?a

(1964 ?.).

Aeey ?ioaa?aeueii? ioe?iee noaio oeaio?aeueii? oa ia?eoa?e/ii?
aaiiaeeiai?ee canoiniaoaaee ?ic?iaeaio iaie iaoiaeeeo neio?iiii?
?aae?ioee?eoeia?ao?? (N?OeA) a eiiieaen? c aoiea?ae?ia?ao??th.

Neio?iiia ?a?no?aoe?y e?eaeo «aeoeai?noue-/an» cae?enithaaeanue ia
aia?ao? O? 1-1 i?ney aiethniiai aaaaeaiiy 131?-ANE (?c ?ic?aooieo 10-15
eAe ia e?eia?ai iane; i?iiaiaaa iaaaioaaeaiiy – 0,35-0,45 iCa) ca
aeiiiiiaith noeeioeeyoe?eieo aeaoaeoi??a: 1- ia ??ai? ?V i?ae?aaa?iiai
i?ii?aeeo ii e?a?e ia?anoa?iaeuei?e e?i?? (i?aea?ae?aeueia e?eaa-?EA);
2- o VIII i?ae?aaa?iiio i?ii?aeeo ii i?aa?e ia?aaei?e aen?ey?i?e e?i?? (
ea?ae?i-ii?oaeueia e?eaa- ?EIA), 3- a ae?eyioe? aaeeeiai iioeee/iiai
aoa?a (oea?aa?aeueia e?eaa ?OeA). C iaoith ciaioaiiy i?iiaiaaiai
iaaaioaaeaiiy ia ueoiaeaeio caeico oai?iio ca 3-5 aei?a aei ianoaaeaiiy
i?ecia/aany ?ic/ei Ethaiey ii 5-8 e?aiaeue 3 ?ace ia aeiao.

Ioe?iea ?ioi?iaoe?? caiaeeeanue aei aei??thaaiiy oeeo?iaeo iieaciee?a ?
iieno ciai?oi?o iciae e?eaeo. Aecia/aeenue ia?aiao?e aaiiaeeiai?ee:
oe a i o ? a e ue i i ? – oaea?iee ia’?i (OI), oaeeeiiee ia’?i (OI),
na?aaei?e a?oa??aeueiee oene (AOn?), caaaeueiee ia?eoa?e/iee ii?? (CII),
eiao?oe??io aoaeoeaiino? oee?eoeyoe?? (EAOe), ?iaioa na?oey (AN),
/anoioa na?oeaaeo nei?i/aiue (*NN), ia’?i oee?eoethth/i? e?ia?
(IOeE), /an iiaiiai eieiiaa?oo ?OI (Oi); i a e i a i e i e a e ? i
a i i a ? a o – ia’?i oee?eoethth/i? e?ia? a eaaaiyo (IOeEe), /an
eieiiaa?oo ?OI ii iaeiio eieo e?iaiia?ao (Oie), a?aenioeiaa
a?aeiioaiiy IOeEe aei IOeE; e a ? ae ? i i i ? o a e ue i i ?
(EIE); i i c e i a i ? – a?oa??aeueiee i?eo?e (Ai?), eai?ey?iee e?iaio?e
(Ee), aaiiciee a?aeo?e (Aao), /an caaaeueii? oee?eoeyoe?? ?OI (*COe).
Oe? aeai? aeicaieyee noaeeoe i?i ia’?ii? oa oaeaee?ni? iieacieee
aaiiaeeiai?ee aaeeeiai ? iaeiai eiea e?iaiia?ao, a oaeiae ?aa?iia?ii?
aaiioee?eoeyoe??. I?e/iio, oaeaee?noue iiceiaiai e?iaioieo ye noia?ii,
oae ? ie?aii ca oacaie – a?oa??aeueiith, eai?ey?iith ? aaiiciith.
Iienoth/e ciai?oi? iciaee, a?aoiaoaaeenue aiie?ooaea, oi?ia, e?ooecia
i?aeeiio ? niaaeo ?OeA- e?eai?.

Oeueo?acaoeia? aeine?aeaeaiiy i?iaiaeeeenue ca aeiiiiiaith aia?aoo
«SIM 5000 PLUS BIOMEDIKA» (?oae?y) a I- ? A – ?aaeeiao ca
caaaeueiii?eeiyoeie iaoiaeeeaie. Aecia/aeenue iieacieee
aioo??oiueina?oeaai? aaiiaeeiai?ee: e?ioeaai- nenoie?/iee (EN?),
e?ioeaai-ae?anoie?/iee (EAe?) ?ici??e e?aiai oeoii/ea (EO);
e?ioeaai-nenoie?/iee (ENI), e?ioeaai-ae?anoie?/iee (EAeI) ia’?ie EO;
o?aeoe?y aeeeaeo EO (OA); oaeaee?noue oee?eoey?iiai aei?i/aiiy aieieii
i?iea?aea (Vcf); ia?aaeiuei-caaei? ?ici??e e?aiai ia?aaena?aey (EI),
i?aaiai oeoii/ea a ae?anoieo (Ae?IO), i?aeoeoii/eiai? ia?aoeiee (IOIae),
caaeiuei? no?iee EO a ae?anoieo (CNEOae); aeneo?n?y IOI (AIOI),
caaeiuei? no?iee EO (ACN).

Noaoenoe/io ia?iaeo ee?i?/ieo ? ?ino?oiaioaeueieo aeaieo i?iaiaeeee
iaoiaeaie aa??aoe?eii? noaoenoeee ia AII 11/34a. Ia/enethaaeenue
aeinoia??i?noue ??cieoe? iieaciee?a i?ae aea??eaie ca e?eoa???i t-oanoo
c aecia/aiiyi nooiai?a naiaiaee ca Nouethaeaioii.

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy.

Aeey aecia/aiiy oeio aaiioee?eoeyoe?? iaoiaeii N?OeA iaie aoea
?ic?iaeaia iiiia?aia (?en. 1), a iniiao yei? aoei iieeaaeaia
ni?aa?aeiioaiiy iieaciee?a oaeeeiiiai ia`?io (OI) ? caaaeueiiai
ia?eoa?e/iiai iii?o (CII) . Ie??i a?ia?- oa a?iie?iaoe/iiai,
a?aeie?aieai? ia?aaeienaeuei? oeie aaiioee?eoeyoe??.

OI e/oa CII aeei.n.

ni-5 CII OI e/oa

10,0 0 10,0

9,0 200 9,0

A?IA?E?IAOE*IEE

8,0 400 8,0

I IA?AAeIENAEUeIEE

7,0 600 7,0

6,7 6,7

6,0 800 6,0

1050

5,0 1000 ?1050 5,0

II?IIE?IAOE*IEE

4,0 1200 4,0

1350

3,0 1400 ?3,3 3,0

?3,3 ?1350 II IA?AAeIENAEUeIEE

2,0 1600 2,0

A?IIE?IAOE*IEE

1,0 1800 ? 1,0

?en 1. Iiiia?aia aeey aecia/aiiy oei?a aaiioee?eoeyoe??

Ni?anoaaeaiiy oei?a aaiioee?eoeyoe?? oa noaae?e IE (oaae.2) aeicaieeei
i?inoaaeeoe caeiiii??i?noue ?o o?ainoi?iaoe?? a?ae a?ia?e?iaoe/iiai
/a?ac ia?aaeienaeuei? aei a?iie?iaoe/iiai ?c iiaeeaeaiiyi iaaeinoaoiino?
e?iaiia?ao.

Oaaeeoey 2

?iciiae?e oai?eo ia i?iea?aeeo

ca noaae??th IE oa oeiii ii?ooaiiy aaiioee?eoeyoe??

Oei Noaae?y IE

aaiioee?eoeyoe?? ? (n=72) IIA (n=69) IIA-III (n=26)

Aan. % Aan. % Aan. %

A?ia?e?iaoe/iee 33 45,8 26 37,7 – –

? -ia?aaeienaeueiee 16 22,2 11 15,9 – –

??-ia?aaeienaeueiee 9 12,5 14 20,3 1 3,8

A?iie?iaoe/iee 14 19,4 18 26,1 25 96,2

E?ea? N?OeA o oai?eo ia i?iea?aeeo, oneeaaeiaiee OIE I no., c ??cieie
oeiaie aaiioee?eoeyoe?? iaee /?oe?, ae?aci? aiie?ooaee oaeeue c ??ciith
?o aenioith. Aeno?aei? ? ieco?aei? ae?eyiee iaee aeinoaoith e?ooecio.
Iaeiae o oai?eo c a?ia?e?iaoe/iei oa ?-ia?aaeienaeueiei oeiii
aaiiaeeiai?ee a?aei?/aeinue caeeaeaiiy i?aai? ? e?ai? oaeeue ?EA. O
oai?eo c a?iie?iaoe/iei oa ??-ia?aaeienaeueiei oeiii aaiioee?eoeyoe??
a?aei?/aeinue cia/ia ca?eueoaiiy i?aai? oaee? ?EA, ui na?ae/eei i?i
?icoe?aiiy i?aaeo eaia? na?oey.

?acoeueoaoe eiiieaeniiai i?iiaiaaiai aeine?aeaeaiiy e?euee?nieo
ia?aiao??a aaiioee?eoeyoe?? o oai?eo ia i?iea?aeeo c IE I no. (oaae.3)
aeicaieeee aeiaanoe, ui, iaa?oue i?e ii/aoeiaeo ii?ooaiiyo, o
a?aeiia?aeue ia iaoieia?/iee i?ioean o i?iea?ae? aeieeathoue
eiiiainaoe?ei? ci?ie an??? na?oeaai-noaeeiii? nenoaie, ye?
?icoe?ithaaeenue ye eiiiainaoi?ii-i?enoinoaaeuei?. ?o oa?aeoa? a
cia/i?e i??? aecia/aany oeiii aaiiaeeiai?ee. Oae, o oai?eo c
a?ia?e?iaoe/iei oa ?-ia?aaeienaeueiei oeiii aaiiaeeiai?ee ca?a?no?iaaii
/?oeo oaiaeaioe?th, aai aeinoia??ia ca?eueoaiiy, /anoioe na?oeaaeo
nei?i/aiue (*NN), na?oeaaiai aeeeaeo (OI) oa oaea?iiai ia`?io (OI) o
ii??aiyii? c eiio?ieueiith a?oiith. Aeey a?iie?iaoe/iiai oa
??-ia?aaeienaeueiiai oei?a aaiiaeeiai?ee o oai?eo ia i?iea?aeeo c IE ?
no. i?eoaiaiia ciaioaiiy aeuacacia/aieo iieaciee?a.

Aiaeii/an, CII o oai?eo c a?ia?e?iaoe/iei oeiii aaiiaeeiai?ee iaa
oaiaeaioe?th aei cieaeaiiy (?=0,05); i?e ia?aaeienaeueieo oeiao ia
aeoiaeea ca iaae? aaee/ei eiio?ieueii? a?oie; i?e a?iie?ia/iiio – aoa
aeinoia??ii i?aeaeuaiei (?0,1); 57,3±1,8% (?6,7 e/oa.), a aeey
??-ia?aaeienaeueiiai oeio – cieaeaiiy (

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