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Клініко-патогенетичні особливості розвитку захворювань печінки у гірників глибоких вугільних шахт Донбасу і шляхи їхньої профілактики: Автореф. дис…

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EOAAINUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAO

I?OEOIAE IEUeAA ?AAI?AIA

OAeE 616.36: 615.322: 622.012. 2-057. 2

EE?I?EI-IAOIAAIAOE*I? INIAEEAINO? ?ICAEOEO CAOAI?THAAIUe IA*?IEE

O A??IEE?A AEEAIEEO AOA?EUeIEO OAOO

AeIIAANO ? OEssOE ?OIUeI? I?IO?EAEOEEE

14.01. 02 – aioo??oi? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Eoaainuee – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Eoaainueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe,

caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie

i?ioani? IEIOE?I Aieiaeeie? sseiae/

Eoaainueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoth/ee eaoaae?ith oa?ai?? oaeoeueoaoa i?neyaeeieiiii? ina?oe

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani?

OA?*AIEI Iaoae?y Ay/aneaa?aia

Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii?

ina?oe ?i. I.E. Ooi?ea, caa. eaoaae?ith aano?i-

aioa?ieia?? ? ae??oioa?ai??

aeieoi? iaaee/ieo iaoe, i?ioani?

IOO?IOeAA Aieiaeeie? Aiaoiae/

Eoaainueeee aea?aeaaiee iaaee/iee oi?aa?neoao,

caa?aeoth/ee eaoaae?ith aini?oaeueii? oa?ai?? ?2

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee oi?aa?neoao
?i.I.I.Aiaiiieueoey IIC Oe?a?ie, eaoaae?a aini?oaeueii? oa?ai?? ?2

Caoeno a?aeaoaeaoueny “29” aeiaoiy 1999?. i 8ii aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee E 29.600.01 i?e Eoaainueeiio aea?aeaaiiio
iaaee/iiio oi?aa?neoao? IIC Oe?a?ie (348045, i. Eoaainuee, ea.50-??//y
Iai?iie Eoaainueea, 1. Oaeaoii: 54-85-57).

C aeena?oaoe??th iiaeia iciaeiieoeny o iaoeia?e a?ae?ioaoe?
Eoaainueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (348045, i. Eoaainuee,
ea.50-??//y Iai?iie Eoaainueea, 1).

Aaoi?aoa?ao ?ic?neaiee “29 aa?aniy” 1999?.

A/aiee nae?aoa? niaoe?ae?ciaaii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani? ______________ A.?. Eieii??oeue

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie Aieea ia i?aai?ci a??iee?a eiiieaeno oe?aeeeaeo
oaeoi??a ae?iaieoeoaa: aaaeeee o?ce/iee o?oae, iaa??aath/ee i?e?iee?iao,
caieeaii?noue iia?o?y, ?ioaineaiee ooi, a?a?aoe?y, i?aeaeuaiee
aa?iiao?e/iee oene, aieea o?i?/ieo ?a/iaei, a?iien?y oa i?aeaeuaiiy
?aae?aoe?eiiai oiio aeceaathoue ci?ie o ooieoe?iioaaii? ?yaeo nenoai oa
i?aai?a c iine?aeoth/ei ?icaeoeii a ieo iaoieia?/ieo ci?i. C oeei
iia`ycaii ca?eueoaiiy caoai?thaaiino? oaooa??a ? cieaeaiiy o?eaaeino?
aeeooy. A caaaeuei?e no?oeoo?? caoai?thaaiino? cia/io a?oio caeiathoue
oai?iae ia/?iee oa aeia/iaea?aeieo oeyo?a. Ii?yae c o?ii?/ieie a??onieie
aaiaoeoaie cia/io ?ieue a?athoue caoai?thaaiiy ia/?iee ci?oaii?
ao?ieia?? (I.ss.Aaaae, 1998; I.A.Oa?/aiei, 1996,1998). I?ioa o ca`ceo c
oei, ui aeacai? caoai?thaaiiy ia yaeythoueny i?ioan?eieie, aea/aiith
oaeoi??a, ye? ni?eythoue ?o ?icaeoeo, a oaeiae ?ic?iaoe? i?io?eaeoe/ieo
caoiae?a, i?eae?ey?oueny iaaeinoaoiuei oaaae.

Caaaeyee oeueiio oeyoe cieaeaiiy caoai?thaaiino? oa ci?oeiaiiy caei?ia`y
oaooa??a ? aaaeeeaei caaaeaiiyi, yea noi?oue ia?aae iaaee/iith iaoeith
Aeiiaano.

Aaaeeee o?ce/iee o?oae a oiiaao iaa??aath/iai i?e?iee?iaoo aeeaieeo
aoa?eueieo oaoo iiaea i?ecaiaeeoe aei ?icaeoeo ino?iai oa o?ii?/iiai
ia?aa??ao ?ia?oiee?a (A.ss.Ieioe?i, TH.A. Ao?iae, 1996; A.N. Ia?aaea??e,
1996 ), c?inoo /enea ??cieo caoai?thaaiue aioo??oi?o i?aai?a (A.I
Aaeooe?ia ? ni?aaao., 1996; A.I.Eiaaoeue 1992) ? ,a oiio /ene?,
caoai?thaaiue ia/?iee (A.A.Eaeueyiia, 1993; A.A. *??e?i, A.?. Iei?ieia,
1994 ).

Anoaiiaeaii, ui ia/?iea ? iaea?eueo /ooeeaith aei aieeao iaa??aath/iai
i?e?iee?iaoo (O.A.Iaaeiaa, 1995) oa o?i?/ieo ?a/iaei (A.I.O?ieia ?
ni?aaao., 1994), aaaa yeeo iineeth?oueny i?e ii?aeiaii? c aeeiiaiiyi
aaaeeeo ?ia?o, i?aeaeuaiei aa?iiao?e/iei oeneii oa ?ioeie oaeoi?aie
i?aecaiiiai na?aaeiaeua. I?e oeueiio a?aecia/aii, ui i?e ia?aa??aaii?
aeieeathoue ooieoe?iiaeuei? (O.E.Naiaii?eiaa ? ni?aaao., 1992) oa
no?oeoo?i? ci?ie ia/?iee (A.A. Ia?aaea??e ? ni?aaao., 1993).

Aaaeeeaa ?ieue o iaoiaaiac? ?yaeo caoai?thaaiue a?aeaiaeeoueny
?ioiieia?/i?e iaaeinoaoiino? (A.I. O?ieia ? ni?aaao., 1993). Ii?yae c
oeei ?ioiia iaaeinoaoi?noue iiaea aeieeaoe o a??iee?a aeeaiei?
aoa?eueii? oaooe i?e aieea? oe?aeeeaeo oaeoi??a i?aecaiiiai na?aaeiaeua
( TH.?. Eoiae??a ? ni?aaao., 1993; N.Oo?euaa, 1997; A.O. *a?iooaiei,
1992).

Ne?ae i?aee?aneeoe, ui a inoaii? ?iee i?aeoe/ii a?aenooi? ?iaioe, ye?
i?enay/ai? iaoai?ciai ?icaeoeo ?ioiiaeao?oeeoiiai noaio oaooa??a. Na?aae
?aaoethth/eo oaeoi??a ?ioi?oaoo aaaeeeaa i?noea caeia? ai?iii oeiono
1-oeiicei (A.A. ss??e?i, ?.I. A?eyeia, 1996).

Iaiao?aeii a?aei?oeoe, ui aei e?ioey ia ae??oai? iaoiaaiaoe/i?
iniaeeaino? oaieiaiai iioeiaeaeaiiy ia/?iee.

Aeyaeaiiy ?aii?o ii?ooaiue no?oeoo?iiai oa ooieoe?iiaeueiiai noaio
ia/?iee oa aea/aiiy oaeoi??a, ye? ni?eythoue ?o ?icaeoeo, iiaea
aeicaieeoe ?ic?iaeoe iaoiaee ?aiiuei? i?io?eaeoeee, e?eoaaiiy oa
?aaa?e?oaoe?? caoai?thaaiue ia/?iee o a??iee?a.

I?ioa ?ia?o, i?enay/aieo eiiieaeniiio aeine?aeaeaiith ?aii?o ii?ooaiue
ooieoe?iiaeueiiai noaio ia/?iee, iaoai?ciai iioeiaeaeoth/iai aieeao
ia?aa??ao ia ?ioiio nenoaio, ye? aeeth/athoue aea/aiiy ai?iiio oeiono
1-oeiiceio, o i?aeoe/ii caei?iaeo i?aecaiieo a??iee?a oa oai?eo ia
o?ii?/iee aaiaoeo aeeaieeo aoa?eueieo oaoo, a aeinooii?e e?oa?aoo?? ia
ciaeaeaii.

Ca`ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie ? oaiaie Aeaia
aeine?aeaeaiiy i?iaiaeeeinue a ieai? iaoeiaeo ?ia?o Eoaainueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, ia eaoaae?? aioo??oi?o oai?ia
oaeoeueoaoo i?neyaeeieiiii? ina?oe ? ? o?aaiaioii IAe? “Aea/eoe
caoai?thaaii?noue a??iee?a aeeaieeo aoa?eueieo oaoo a?ia?oii?/iith
oai?iaith, ?oai?/iith oai?iaith na?oey, oai?iaaie ie?ie, ia/?iee ?
na/iaea?aeieo oeyo?a oa ?ic?iaeoe e?eoaaeueii-i?io?eaeoe/i? oa
?aaa?e?oaoe?ei? i??ii?e?inoaa” (? aea?aeaaii? ?a?no?aoe??-
?01890069866).

Iaoith aeine?aeaeaiiy aoei aeyaeaiiy ?aii?o ee?i?ei-eaai?aoi?ieo
e?eoa???a oa aea/aiiy ie?aieo iaoai?ci?a ?icaeoeo caoai?thaaiue ia/?iee
o a??iee?a aeeaiei? aoa?eueii? oaooe oa ?ic?iaea caniaa ?o i?io?eaeoeee.

Aeey aeinyaiaiiy iinoaaeaii? iaoe iaiao?aeii aoei ae??oeoe ne?aeoth/?
caaaeaiiy :

1. Aea/eoe caoai?thaai?noue i?aai?a aaiaoia?e?a?ii? nenoaie o a??iee?a
aeeaiei? aoa?eueii? oaooe.

2. Aea/eoe ooieoe?iiaeueiee noai ia/?iee a??iee?a ia iniia?
aeine?aeaeaiiy a?io?i?/ieo iieaciee?a caeaaeii a?ae aaaeeino?
aeeiioth/eo ?ia?o, a?eo oa noaaeo ?iaioe a i?aecaiieo oiiaao.

3. Aea/eoe noai ?ioiiiai noaoono o i?aecaiieo a??iee?a aeeaieeo
aoa?eueieo oaoo, c`ynoaaoe iayai?noue ci?i caeaaeii a?ae aaaeeino?
aeeiioth/eo ?ia?o, a?eo oa noaaeo ?iaioe a i?aecaiieo oiiaao.

4. Anoaiiaeoe ci?io eiioeaio?aoe?? ai?iiio oeiono 1-oeiiceio, aieea ia
eiai ??aaiue aaaeeino? aeeiioth/eo ?ia?o, a?eo oa noaaeo ?iaioe a
i?aecaiieo oiiaao oa anoaiiaeoe eiai aca?iica`ycie c iniiaieie
ia?aiao?aie ?ioiia?aie.

5. Aecia/eoe ?ieue iaa??aath/iai i?e?iee?iaoo a ?icaeoeo ii?oieia?/ieo
ci?i oa ii?ooaiue ooieoe?iiaeueiiai noaio ia/?iee
(ee?i?ei-aenia?eiaioaeueia aeine?aeaeaiiy).

6. ?ic?iaeoe oa i?iaanoe ai?iaaoe?th iaoiaea ?aiiuei? i?io?eaeoeee
caoai?thaaiue ia/?iee o i?aecaiieo a??iee?a aeeaiei? aoa?eueii? oaooe.

Iaoeiaa iiaecia ?iaioe Aia?oa aeyaeai? ii?ooaiiy ooieoe?? ia/?iee
a??iee?a, ye? ae?aaeathoueny o cieaeaii? ci?noo aeueaoi?i?a a ne?iaaooe?
e?ia?, iniaeeai cia/i? o iieiaeeo a??iee?a oa oaooa??a c i?aecaiiei
noaaeai aei 5 ?ie?a; a?aeiini?i i?aeaeuaiiyi ??aiae o?ainai?iac, ??aiy
oieanoa?eio oa -e?iii?ioa?ae?a o ne?iaaooe? e?ia?, ia?aaaaeii o
?ia?oiee?a iniiaieo i?ioan?e, aeeiioth/eo aaaee? ?iaioe a iani?eyoeeaeo
oiiaao a??ieo ae?iaie.

Aia?oa aeyaeaii cia/ia cieaeaiiy ??aith ai?iiio oeiono 1-oeiiceio o
a??iee?a aeeaieeo aoa?eueieo oaoo.

Aia?oa anoaiiaeaii, ui o a??iee?a ai?iii oeiono 1-oeiicei i?eeia?
o/anoue o ?aaoeyoe?? ?ioiiiai noaoono.

Anoaiiaeaiee ei?aeyoe?eiee ca`ycie 1-oeiiceio c iniiaieie ia?aiao?aie
?ioiia?aie oaooa??a.

?ic?iaeaii oa ai?iaiaaii iiaee iaoiae ?aiiuei? i?io?eaeoeee
caoai?thaaiue ia/?iee o a??iee?a.

I?aeoe/ia cia/ou?noue io?eiaieo ?acoeueoao?a ?acoeueoaoe aeine?aeaeaiiy
aeathoue iiaeeea?noue oe?iei aeei?enoiaoaaoe o i?aeoe/i?e ?iaio?
e?eoaaeueieo caeeaae?a ei?aeoe?th ?ioiiiai noaoono oa ??aith ai?iiio
oeiona 1 –oeiiceia aeey i?io?eaeoeee caoai?thaaiue ia/?iee o i?aecaiieo
a??iee?a aeeaieeo aoa?eueieo oaoo.

Iaea?aeai? aeai? /?oei aeacothoue ia iaiao?aei?noue aaaaeaiiy cacia/aieo
ooieoe?iiaeueieo iieaciee?a ia/?iee a iaia`yceiaee ia?ae?e
aeine?aeaeaiue i?e i?iaaaeaii? ia??iaee/ieo i?io?eaeoe/ieo iaeyae?a o
?ia?oiee?a iniiaieo i?ioan?e aeeaieeo aoa?eueieo oaoo.

I?iaiaeeoe ui??/i? aeine?aeaeaiiy o in?a, a?aeianaieo aei a?oi ?eceeo,
noaio ?ioiii? nenoaie oa ??aith ai?iiia 1-oeiiceia aeey aeyaeaiiy
?ioiiaeao?oeeoiiai noaiiaeua c iaoith nai?/anii? ei?aeoe??.

Iniiai? ?acoeueoaoe i?iaaaeaieo aeine?aeaeaiue ai?iaaaeaeai? a i?aeoe/io
?iaioo Eoaainueei? iaeanii? ee?i?/ii? e?ea?i?, iaaeeei-nai?oa?ieo /anoei
i?no Ia?aiiaenueea, Aao?ooaai, Ae/aanueea, Naa?aeeiaee oa ?iaaiueee.

Iaea?aeai? aeai? aeei?enoiaothoueny a eaeoe?eiiio eo?n? aeey nooaeaio?a,
e?ea??a-?ioa?i?a oa e?ea??a-neooa/?a oaeoeueoaoo i?neyaeeieiiii? ina?oe
Eoaainueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, eaoaae?ao aioo??oi?o
oai?ia Aeiiaoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, Oe?a?inueei?
iaaee/ii? noiiaoieia?/ii? aeaaeai?? (Iieoaaa).

Iniaenoee aianie caeiaoaa/a Aeena?oaioii naiino?eii i?iaiaeeany iaeyae
a??iee?a oa aiae?c iaaee/ii? aeieoiaioaoe?? c iaoith i?aeai?o
eiioeiaaioo aeey iiaeeaeaiiai aeine?aeaeaiiy, caa?? e?ia? oa cacia/aiiy
??aith 1-oeiiceio. Aaoi? i?eeiaa o/anoue a i?iaaaeaii? ii?oieia?/iiai,
?ioiieia?/iiai oa a?io?i?/iiai aeine?aeaeaiue, naiino?eii aoa
i?iaaaeaiee aiae?c iaea?aeaieo ?acoeueoao?a ii eiii`thoa?i?e i?ia?ai?,
yeo a?i naiino?eii aaeaiooaaa aeey i?iaaaeaiiy aeaii? ?iaioe.
Caeiaoaa/ai naiino?eii i?iaaaeaiee aea?? i?aia?aoo aeey ei?aeoe??
aeyaeaieo ci?i oa ?ic?iaeaia noaia eiai canoinoaaiiy.

Ai?iaaoe?y ?iaioe Iaoa??aee aeena?oaoe?? aeiiia?aeaeenue ia
?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?aioe?? “Aeinyaiaiiy oa
iaae??oaii? ieoaiiy aano?iaioa?ieia??” (Oa?e?a. 1998), ? iaoe?iiaeueiiio
eiia?an? Oe?a?ie c ?ioiieia??, aea?aieia?? oa ?ioii?aaa?e?oaoe??
(Aeoooa, E?ei, 1998), XIV c`?cae? oa?aiaao?a Oe?a?ie (Ee?a, 1998).

No?oeoo?a oa ianya aeena?oaoe?? Aeena?oaoe?y aeeeaaeaia ia 141
noi??ieao, aeeth/ath/e anooi, iaeyae e?oa?aoo?e, /ioe?e aeaae aeanieo
aeine?aeaeaiue, iaaiai?aiiy, aeniiaee, nienie aeei?enoiaaieo aeaea?ae oa
i?iiiceoe?e. Aeena?oaoe?y i?noeoue 13 oaaeeoeue oa 32 iaethiea. Nienie
aeei?enoaieo aeaea?ae neeaaea? 154 a?o/eciyieo ? 42 ?iicaiieo
e?oa?aoo?ieo iineeaiue.

Ioae?eaoe?? Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 14 ?ia?o, a oiio
/ene? 7 noaoae a oaoiaeo aeaeaiiyo ? 2 iniaenoeo noaoo?. Ioi?ieai? oa
io?eiai? cana?ae/aiiy ia 3 ?aoe?iiae?caoi?nuee? i?iiiceoe??.
Cai?iiiiiaaii can?a i?io?eaeoeee ?ioiiaeao?oeeoiiai noaio o a??iee?a
aeeaieeo aoa?eueieo oaoo (Iaoaio Oe?a?ie ?21063 A a?ae 04.11.97 ?.).

INIIAIEE CI?NO

Iaoa??aee ? iaoiaee aeine?aeaeaiiy Ia oaoo? “Ieeaii?” AeOE
“Eoaainueeaoa?eey” aoei i?iaaaeaii eiiieaenia aeine?aeaeaiiy 850
a??iee?a, c ieo a?ae?a?aii 77 i?aeoe/ii caei?iaeo i?aecaiieo ?iai/eo.
A?ae?a?ai? ?ia?oieee ia ceiaaeeaaee aeeiaieue ca?aeii aeaieo
aeeniaina?iiai iaeyaeo, aieaooaaiiy oa a?aenooiino? ?a?no?aoe?? a
ia?eieia?/iiio aeeniaina??. C ieo ?ia?oieee “iniiaieo” oaooa?nueeeo
i?ioan?e (A?IC, i?io?aeieee), aeeiioth/e aaaee? ?iaioe a iaea?eueo
iani?eyoeeaeo oiiaao i?aecaiiiai i?e?iee?iaoo, neeaee 34 /ieia?ea.

O an?o ?ia?oiee?a aoei i?iaaaeaii aeine?aeaeaiiy a?e??oa?io, caaaeueiiai
a?eeo, aeueaoi?i?a, aeiaoe?i?a, oieanoa?eio, -e?iii?ioa?ae?a, o?iieiai?
i?iae, aeai?iiai? ai?iio?ainoa?ace (AeAO) oa ania?aa?iiai?
ai?iio?ainoa?ace (AnAO) o ieaci? e?ia?, ia?ea??a a??oniiai aaiaoeoo ca
caaaeueiii?eeiyoeie iaoiaeeeaie (A.A.Ia?aaea??e, TH.?. Oiaeaanueeie,
1993). I?e aiae?c? iaea?aeaieo iieaciee?a ia/enethaaany eiao?oe??io aea
??o?no (AnAO/AeAO) (N.Ae. Iiaeeiiaa, 1998).

Aeey aecia/aiiy aieeao ?iaioe a??iee?a a i?aecaiieo oiiaao ia aea/a?i?
iieacieee ?ia?oieee aoee ?icae?eai? ia a?oie: ? – on? ianoaaeaii?
a??iee? (77 /ie.). C ieo iniae, ui aeeiiothoue aaaeeo o?ce/io ?iaioo a
iaea?eueo iani?eyoeeaeo oiiaao i?aecaiieo ae?iaie neeaee 34 /ie. ? aoee
a?aeianai? aei ?? a?oie; ??? a?oia – iniae, ui aeeiiothoue ?iaioe
na?aaeiuei? aaaeeino? a i?aecaiieo oiiaao (43 /ie.). Eiio?ieueio a?oio
neeaee 20 /ieia?e.

Aeey anoaiiaeaiiy aieeao a?eo oa noaaeo ?iaioe a i?aecaiieo oiiaao ia
aea/a?i? iieacieee on? ianoaaeai? aoee ?icae?eaii? ca a?eii ia oae?
a?oie : 20-30 ?ie?a (13 /ie.); 31-40 ?ie?a (39 /ie.); 41-50 ?ie?a (14
/ie.) oa 51-60 ?ie?a 911 /ie.); oa ca noaaeai: aei 5 ?ie?a (6 /ie.);
5-10 ?ie?a (17 /ie.); 11-15 ?ie?a (25 /ie.);16-20 ?ie?a (13 /ie.), 21-25
?ie?a (16 /ie.).

I?e aeine?aeaeaii? ee?oeiii? oa aoii?aeueii? eaiie ?ioi?oaoo a??iee?a
cacia/aany ci?no e?ioioeeo?a (E) a ia?aoa??/i?e e?ia? (Boyum A., 1986).
Cacia/aiiy O-e?ioioeeo?a, noaiiioeyoe?e O-oaeia??a / ?iaeoeoi??a oa
O-noi?ani??a /e?ea??a, iaoo?aeueieo e?ea??a, A-e?ioioeeo?a canoinoaaeiny
c aeei?enoaiiyi iaiae? iiiieeiiaeueieo aioeo?e CD3, CD4, CD8, CD22 (Orho
Diagnostic Systems Inc., NOA)(A.I.O?ieia ? ni?aaao., 1989). Iae?/oaaee
?aaeoe?th a eai??? Ai?y?aa i?ae na?oeiaei i?e?ineiiii. ?ioiiaeiaoe?ie
ne?iaaoee e?ia? eeania A, M, G cacia/aee iaoiaeii ?aae?aeueii?
?ioiiae?ooc?? (Mancini G., 1965). Cacia/aiiy ??aith Oe?E i?iaiaeeeeny
iaoiaeii Eao?? c iine?aeoth/ei ia?ae?eii a aeine?aeaeo?i?e ne?iaaooe?;
?acoeueoao ae?aaeaee a oiiaieo iaeeieoeyo (Haskova V., 1977).

Aecia/aiiy ci?noo a ne?iaaooe? e?ia? 1-oeiiceia canoinoaaeiny
?aae?i?ioiieia?/iei iaoiaeii a eaai?aoi??? ?ioiia?ioaoiieia?? IAe?
oaoiieia?? e?iaicai?ithaa/ae oa ai?iiiaeueieo i?aia?ao?a, i. Iineaa
(caa. eaai?aoi???th e.a.i. A.I.Oin?ae).

Aeey aea/aiiy aieeao oaiea ia no?oeoo?o ia/?iee aoei cae?eniaii
aenia?eiaioaeueia aeine?aeaeaiiy 75 a?eeo iaoethe?a, yeeo ?ici?uoaaee a
oaieia?e eaia?? c oaiia?aoo?ith iia?o?y 45iN oa a?aeiiniith aieia?noth
65%. Eiio?ieueio a?oio neeaee 10 ?ioaeoieo oaa?ei.

On? oaa?eie ?ici?uoaaeenue a eaia?? iaeiiiiiaioii oa caaeaaeeny o /ania?
oi/ee, a?aeiia?aeii noaae?yi: ?ooiaiai caoaeaeaiiy (?C), oaieiaiai
oaea?o (OO) oa e?ioeaai? noaae?? oaieiaiai oaea?o – aaii?? (Aa), ui
niinoa??aaeiny /a?ac 2 aiaeeie 25±5 oaee., 3 aiaeeie 25±5 oaee. oa 4
aiaeeie 25±5 oaee. a?ae ii/aoeo aenia?eiaioo a?aeiia?aeii. E??i
iaeiie?aoiiai ia?aa??ao i?iaiaeeeiny o?ii?/ia ia?aa??aaiiy oaa?ei aei
noaae?? ?C uiaeaiii i?ioyaii 7 aei?a.

Aeey ii?oieia?/iiai aeine?aeaeaiiy oaa?ei caaeaaee oeyoii aeaeai?oaoe??
ia oii? ao??iiai ia?eico. Oeaieio ia/?iee i?aeaeaaaee
aeaeo?iiii-i?e?ineii?/iiio, aeaeo?iiiia?noio?i?/iiio aeine?aeaeaiith
(JEM – 7A, ssiii?y) oa na?oeia?e i?e?ineii??. E?euee?nia ii?oiiao??y
canoiniaoaaeany ca aeiiiiiaith n?oee A.A.Aaoaiae?eiaa.

E?ea?nueeee can?a “Ni??oe?ia” i?eeiaany 20 ?ia?oieeaie ii 2 oaaeaoee
(1a) o?e ?ace ia aeaiue i?ioyaii 7-10 aei?a (iiia? ?a?no?aoe?eiiai
iina?ae/aiiy 3770).

Iaea?aeai? aeai? ia?iaethaaeenue ca aeiiiiiaith niaoe?aeueiiai iaeaoo
i?eeeaaeieo i?ia?ai ia AII ?AI ?N-486 AO, neeaaeaieo ia iia? Foxpro. I?e
oeueiio cacia/aeenue na?aaei? aaee/eie, ?o iiieeea, e?eoa??e
aeinoia??iino? ca aeiiiiiaith t-Nouethaeaioa oa eiao?oe??ioo ei?aeyoe??
r.

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy. Caoai?thaai?noue oai?iaaie
ia/?iee oa aeia/iaea?aeieo oeyo?a ia oaoo? “Ieeaii?” i?aeaeuoaaeany c
1993 ii 1996 ??e. Aei oiai ae, o 1996 ?ioe? a?aeaoeiny iaea?eueoa
ca?eueoaiiy iieaciee?a: a aeiaaeeao ia 1,3 (92,8%; ?ioaineaiee iieaciee
caoai?thaaiino?– ?.i. ia 1000 ?ia?oiee?a) oa a aeiyo iai?aoeacaeaoiino?
ia 38,2 (100,3%) i?e oeueiio, caoai?thaai?noue neeaea 34 aeiaaeea oa 948
aei?a oei/aniai? ao?aoe i?aoeacaeaoiino?, oa aoea naiith aenieith a
aoa?eueiicaeiaoaath/?e aaeoc? Oe?a?ie, oa iaeaea aaea?/? ia?aa?eueooaaea
na?aaei? iieacieee a Eoaainuee?e iaeano?.

I?ney eiiieaeniiai i?io?eaeoe/iiai iaeyaeo 850 a??iee?a aeey oe???
?iaioe aoee a?ae?a?ai? 77 i?aeoe/ii caei?iaeo oaooa??a.

?acoeueoaoe aiae?co nea?a a??iee?a iieacaee, ui iaea?eueo
?iciianthaeaeaieie na?aae a??iee?a aoee: anoaiiaaaaoaoeaiee n?iae?ii
(3,2%), aeeniaine/iee n?iae?ii (2,9%), nea?ae ia aaaee?noue oa aie? a
i?aaiio i?ae?aaa?`? (1,8%), aie? a noaeiaao (1,2%). I?e oeueiio, o 21,5%
a??iee?a ca aeaieie oeueo?acaoeiaiai aeine?aeaeaiiy aecia/ai?
??ciiiai?oi? ci?ie (ca?eueoaiiy, aeaoi?iaoe?y oa ooieu?iiy no?iie
aeia/iiai i?oo?a; i?enooi?noue a?ia?aoiaaiii? aca?n? oa inaaeeo a
ii?iaeiei? aeia/iiai i?oo?a, ca?eueoaiiy ?ici???a, aeeoocia ca?eueoaiiy
aoiaaiiino? oa iaiaeii?iaeiino? ia?aio?ie ia/?iee).

O an?o ianoaaeaieo ia?ea??a a??oniiai aaiaoeoo cacia/aii ia aoei.

Aeey ooi/iaiiy oa?aeoa?o aeyaeaieo ooieoe?iiaeueieo ci?i ia/?iee aoei
cae?eniaii a?io?i?/ia aeine?aeaeaiiy e?ia? a??iee?a.

Iaea?aeai? iieacieee aiae?coaaeenue caeaaeii a?ae aaaeeino? ?ia?o, a?eo
oa noaaeo a??iee?a. I?e oeueiio anoaiiaeaii, ui caaaeueiee a?eie a e?ia?
a??iee?a neeaa 68,69 – 73,0 a/e. I?e ii??aiyii? c eiio?ieueiith a?oiith
(74,6±2,8 a/e) o ?ia?oiee?a ?? a?oie, aeeiioth/eo aaaee? ?iaioe a
iaea?eueo iani?eyoeeaeo i?e?iee?iaoe/ieo oiiaao, anoaiiaeaii cieaeaiiy
(?

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