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EOAAINUeEEE AeA?AEAAIEE IAAeE*IEE OI?AA?NEOAOIIC OE?A?IE

AeIEEINUeEA Ia??y Aaa??ae?aia

OAeE 612. 017.1: 616. 234-12-005. 4-08

EE?I?EI-IAOIAAIAOE*IA OA?AEOA?ENOEEA ? E?EOAAIIss OAI?EO IA O?II?*IEE
IANO?OEOEAIEE A?IIO?O C NOIOOIUeITH ?OAI?*IITH OAI?IAITH NA?Oess

14.01.02 – aioo??oi? oai?iae

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa
iaaee/ieo iaoe

Eoaainuee – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Eoaainueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?IIC
Oe?a?ie

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani?Ioo?ioeaa Aieiaeeie?
Aiaoiae/,

Eoaainueeee aea?aeaaiee iaaee/iee oi?aa?neoao IIC Oe?a?ie,caa?aeoaa/
eaoaae?e aini?oaeueii? oa?ai?? ?2

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani?Aaa?enthe Aieiaeeie?
Einoyioeiiae/?inoeooo ooec?ao??? ? ioeueiiiieia?? ?i. O.A. ssiianueeiai
AII Oe?a?ie (i. Ee?a), caa?aeoaa/ ee?i?ei-ooieoe?iiaeueiiai a?aeae?eo

aeieoi? iaaee/ieo iaoe, i?ioani?Ieioe?i Aieiaeeie? sseiae/Eoaainueeee
aea?aeaaiee iaaee/iee oi?aa?neoaoIIC Oe?a?ie, caa?aeoaa/ eaoaae?e
oa?ai?? OIaeI

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee oi?aa?neoao
?i. I.I.AiaiiieueoeyIIC Oe?a?ie (i. Ee?a), eaoaae?a aini?oaeueii?
oa?ai?? ? 2

Caoeno aeena?oaoe?? a?aeaoaeaoueny «29» aeiaoiy 1999 ?. i 8-30
aiaeei?ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee E.29.600.01 i?e
Eoaainueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? IIC Oe?a?ie (348045,
i. Eoaainuee, ea. 50??//y Iai?iie Eoaainueea, 1; o. 54-85-57)

C aeena?oaoe??th iiaeia iciaeiieoeny a iaoeia?e a?ae?ioaoe? Eoaainueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (348045, i. Eoaainuee, ea. 50??//y
Iai?iie Eoaainueea, 1)

Aaoi?aoa?ao ?ic?neaiee “20” na?iiy 1999 ?.

A/aiee nae?aoa?niaoe?ae?ciaaii? a/aii? ?aaee,aeieoi? iaaee/ieo iaoe,
i?ioani? ________________ A.?. Eieii??oeue

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. A inoaii? aeanyoee?ooy iicia/eeany /?oea
oaiaeaioe?y aei ?inoo caoai?thaaiino? ia o?ii?/iee a?iio?o (ca aeaieie
Anana?oiuei? i?aai?caoe?? ioi?iie caei?ia’y caoai?thaaiiy cono??/a?oueny
o 38 % ianaeaiiy a?eii iica 45 ?ie?a ? o 47 % – ca 55 ?ie?a), yea
iaoiiaeaia ieceith i?e/ei (Oauaiei TH.?., 1997). A?eueo?noue
aeine?aeiee?a iaceaathoue na?aae ieo neeueia caa?oaeiaiiy aoiinoa?iiai
iia?o?y, iniaeeai o aaeeeeo i?noao ? ?iaeono??aeueieo oeaio?ao,
??ciiiai?oieie aa?aneaieie iiethoaioaie (Naiaiiaa ?.?. ? ni?aaao., 1993;
Ieioe?i A.ss., 1998), ui iaoiiaeth? o?ii?/ia ooeiaeaeaiiy neeciaeo
iaieiiie a?iio?a ? a?iio?ie, aeieeiaiiy iaoaieac?? iie?eaiiai ai?oae?th
(Linden M. et al., 1993), cieaeaiiy ooieoe?iiaeueii? aeoeaiino?
aeueaaiey?ieo iae?ioaa?a (Hadnagy W., 1994), ?icaeoie o?a?ico a
eaaaiaa?e ia?aio?i?, ou?eueiaiiy no?iie aeueaaie, ae??aieo eaaaiaaeo
a?oa??e ? a?oa??ie, iia??oaiiy ae?aiaaeii? ooieoe?? oa niaci a?iio?a
(Rennard S.I. et al., 1993). E??i oiai, cacia/ai? /eiieee aeeeeeathoue
nenoaiia cieaeaiiy ?aaeoeaiino? i?aai?cio, noai?thth/e ia?aaeoiiae aeey
?icaeoeo ?ioaeoe?eieo caoai?thaaiue (Postma D.S. et al., 1995). Ne?ae
a?aecia/eoe, ui c ?icaeoeii ci?i o eaaaiyo ae?y iani?eyoeeaeo aeciaaiieo
/eiiee?a, ui aeeeeea? iioeiaeaeaiiy, ona a?eueo c?inoa?, oiio ye
ciaioo?oueny cae?ai?noue eaaai?a ae?i?ioaaoe iiethoaioe – ooai?th?oueny
naiai ?iaeo “oeaia eiei” (Sweeney T.D. et al., 1995). I?e oaeiio
cia/iiio iioe?aii? caoai?thaaiiy aoaeoeai?noue e?eoaaiiy caeeoa?oueny
iaaeinoaoiueith – e?eoaaeuei? noaie, ui ?niothoue, /anoi ia o?eueee ia
i?ecaiaeyoue aei aee?eoaaiiy, aea e ia iie?auothoue yeino? aeeooy oai?eo
(*o/aeei A.I., 1997). Iniaeeai? aeooaeueiino? iaaoea o oaia??oiueiio
/an? i?iaeaia noi?niaiiy o?ii?/iiai iano?oeoeaiiai a?iio?oo (OIA) oa
?oai?/ii? oai?iae na?oey (?ON), aiane?aeie, c iaeiiai aieo, c?inoaiiy
caoai?thaaiino? ia iaeaeaa caoai?thaaiiy, a c ?ioiai – iioe?aiino? iaio
caoai?thaaiue o a?eia?e a?oi? iica 40 ?ie?a, ni?euei?noth aeayeeo
/eiiee?a ?eceeo, cie?aia iae?iiy, ni?euei?noth iaoiaaiaoe/ieo
iaoai?ci?a, iniaeeai cnoao aaeaino “ia?aeenia ieeneaiiy e?i?ae?a –
aioeieneaeaioiee caoeno” (“IIE–AIC”), a oaeiae ae?aaeaiei aca?iiei
iaoyaeaiiyi ia?aa?ao (Wallwork J., 1994; Hawthorne V.M. et al., 1995).

C iaeyaeo ia cia/io ?ieue ii?ooaiue o nenoai? “IIE–AIC” i?e iaio
caoai?thaaiiyo, aaaaea?oueny aeioe?eueiei canoinoaaiiy i?aia?ao?a c
aioeieneaeaioiith ? aioea?iienaioiith ae??th a eiiieaeniiio e?eoaaii?
oai?eo ia OIA oa ?ON (Eiaai A.O., 1997; Aaa?enthe A.E., 1998). Iniaeeai
i?eiaaeieie a aeaiiio aeiaaeeo ? i?aia?aoe, ui ii?aeiothoue iaeaeaa
cacia/aieo oa?iaeiaeeiai?/ieo aoaeoe, – aaieoee oa eaa?oeaoei. E??i oiai
aeioe?euei?noue canoinoaaiiy aaieoeeo iineeth?oueny, ia iaoo aeoieo,
caeaoi?noth i?aia?aoo noeioethaaoe ?aaaia?aoe?th a?iio?aeueiiai
ai?oae?th (Eiaeeyinueeee A.?., 1995). Eaa?oeaoei aoa ia?aiei iaie,
a?aoiaoth/e ?ieue o iaoiaaiac? a?iio?aeueii? iano?oeoe?? ?
ei?iia?iniacio e?iieneaaiacieo iaoaaie?o?a a?ao?aeiiiai? eeneioe
(Eie/?i TH.I., 1996; Ieioe?i A.ss., 1998).

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa aeeiiaia
ca?aeii c ieaiii IAe? Eoaainueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo
? ? o?aaiaioii IAe? i??i?eoaoiiai o?iainoaaiiy “Ee?i?ei-iaoiaaiaoe/ia
oa?aeoa?enoeea caoai?thaaiue aioo??oi?o i?aai?a, ?o ei?aeoe?y”,
(? aea?ae?a?no?aoe?? 01980002238).

Iaoa aeine?aeaeaiiy – ?ic?iaeoe aoaeoeai? iaoiaaiaoe/ii iaa?oioiaai?
iaoiaee ei?aeoe?? ii?ooaiue ee?oeiieo /eiiee?a ianiaoeeo?/ii?
?acenoaioiino? a?iio?a ? i?noeaai? nenoaie AIC o oai?eo ia OIA o
noeoiiino? c ?ON.

Caaea/aie ?iaioe aoee:

1) aea/eoe iniaeeaino? ee?i?/ieo i?iya?a o?ii?/iiai iano?oeoeaiiai
a?iio?oo o oai?eo ia ?oai?/io oai?iao na?oey;

2) noa?aeoa?ecoaaoe iniaeeaino? ii?ooaiue ee?oeiiiai ? aoii?aeueiiai
?ioi?oaoo o oai?eo ia o?ii?/iee iano?oeoeaiee a?iio?o ?c noiooiueith
?oai?/iith oai?iaith na?oey;

3) i?iaanoe ioe?ieo e?euee?nieo oa ye?nieo iieaciee?a, ui
oa?aeoa?ecothoue i?noeaao ianiaoeeo?/io ?acenoaioi?noue a?iio?a o oai?eo
ia o?ii?/iee iano?oeoeaiee a?iio?o o noeoiiino? c ?oai?/iith oai?iaith
na?oey;

4) aeine?aeeoe ooieoe?iiaeueiee noai ieneaeaioieo ? aioeieneaeaioieo
nenoai a?iioiaeueaaiey?iiai i?inoi?o o aeaii? eaoaai??? oai?eo;

5) aea/eoe aieea aaieoeeo ? eaa?oeaoeio ia ee?i?/iee ia?aa?a ? oaii
iiiiaethaaiiy ii?ooaiue ee?oeiieo /eiiee?a ianiaoeeo?/ii? ?acenoaioiino?
a?iio?a o oai?eo ia o?ii?/iee iano?oeoeaiee a?iio?o o noeoiiino? c
?oai?/iith oai?iaith na?oey.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. Aoei aeyaeaii iniaeeaino?
ee?i?/ii? ea?oeie oa ia?aa?ao OIA ia oe? ?ON. I?iaeaiiino?iaaii ?ieue
ii?ooaiue aeoeaiino? /eiiee?a ee?oeiii? oa aoii?aeueii? eaiie ?ioi?oaoo,
i?noeaai? ianiaoeeo?/ii? ?acenoaioiino? oa aioeieneaeaioiiai caoenoo
a?iio?a, oiui, o iaoiaaiac? noi?nii? iaoieia?? aeaiiai aeaeo. Aia?oa
iieacaii aca?iica’ycie ooieoe?iiaeueiiai noaio ee?oeiieo /eiiee?a
i?noeaaiai ianiaoeeo?/iiai caoenoo a?iio?a ? ai?noo a
a?iioiaeueaaiey?iiio i?inoi?? aeoeaiaaieo oi?i eenith, ui ?
?ioaa?aeueiei iieacieeii aaeaino a nenoai? “IIE – AIC”. Anoaiiaeaii
ei?aeyoe?eiee aca?iica’ycie i?ae aeyaeaieie ii?ooaiiyie i?noeaaiai
caoenoo ? oyaee?noth aeeoaeueii? iaaeinoaoiino?, ui na?ae/eoue i?i
aca?iicoiiaeai?noue oeeo ?iceaae?a. Iaoiaaiaoe/ii iaa?oioiaaii
aeioe?euei?noue aeeth/aiiy aaieoeeo oa eaa?oeaoeio aei eiiieaeniiai
e?eoaaiiy oai?eo ia OIA o noeoiiino? c ?ON. Aoaeoeai?noue i?aia?ao?a
aioeieneaeaioii? e aioea?iienaioii? ae?? a e?eoaaii? oai?eo ia OIA o
noeoiiino? c ?ON aeiaaaeaia ia i?aenoaa? ee?i?/ieo aeaieo, a oaeiae
oeyoii ioe?iee noaio nenoaie i?noeaaiai caoenoo oa i?yiiai
aeaeo?io?i?/iiai aeine?aeaeaiiy a?iioiaeueaaiey?ieo ciea?a (AAC).

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. Ia i?aea?oio? iaoiaaiaoe/ii?
oa?aeoa?enoeee OIA ia oe? ?ON, cie?aia aeyaeaiiai i?eai?/aiiy ee?oeiieo
/eiiee?a i?noeaai? ianiaoeeo?/ii? ?acenoaioiino? oa i?noeaaiai caoenoo,
?ic?iaeaii canaaee aei i?ecia/aiiy aioeieneaeaio?a ? aioea?iienaio?a o
eiiieaeniiio e?eoaaii? oai?eo. Iayai?noue o oai?eo ia OIA c? noiooiueith
?ON ae?aaeaiiai neiae?iio aca?iiiaoyaeaiiy, a oaeiae i?eai?/aiiy
aioeieneaeaioiiai caoenoo oa eeniaaicaeaaeieo iaoaaie?/ieo i?ioean?a a
ee?oeiao, ye? cae?eniththoue i?noeaao ianiaoeeo?/io ?acenoaioi?noue,
aeicaiey? aaaaeaoe aeioe?eueiei canoinoaaiiy i?aia?ao?a, ui ii?aeiothoue
aioeieneaeaioi? oa aioea?iienaioi? aeanoeaino? – aaiaoeeo oa
eaa?oeaoeio. Iaea?eueo ?ioi?iaoeaieie aeey aecia/aiiy aoaeoeaiino?
i?iaaaeaii? aioeieneaeaioii? ? aioea?iienaioii? oa?ai?? o oai?eo c oaeei
aa??aioii noi?nii? iaoieia?? ? iieacieee oeeoia?aie a?iioiaeueaaiey?iiai
i?inoi?o, ??aaiue aeeoo?caeaoiino? ee?oeiieo aeaiaio?a, a oaeiae ai?no a
AAC aeoeaieo oi?i eenith.

?acoeueoaoe aeine?aeaeaiiy ai?iaaaeaeai? a e?eoaaeueio ?iaioo Iaeanii?
ee?i?/ii? e?ea?i? i. Eoaainueea, Iaeanii? ee?i?/ii? ?ioaeoe?eii? e?ea?i?
i. Oa?eiaa, Iaeanii? ee?i?/ii? e?ea?i? i. Aeiiaoeueea,
ioeueiiiieia?/iiai a?aeae?eaiiy i?nueei? e?ea?i? ? 7 i. Eoaainueea. Iia?
aeai?, ui io?eiaii, ai?iaaaeaeai? aei iaa/aeueiiai i?ioeano Eoaainueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, Aeiiaoeueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo oa Oe?a?inueei? noiiaoieia?/ii? aeaaeai??.

Iniaenoee aianie caeiaoaa/a. Caeiaoaa/ai iniaenoi i?iaaaeai? ee?i?/ia oa
?ino?oiaioaeueia ianoaaeaiiy 122 oai?eo ia OIA, o 84 c yeeo
caoai?thaaiiy noi?nithaaeiny c ?ON, neeaaeai? e?eoaaeuei? i?ia?aie c
o?aooaaiiyi canaae aei i?ecia/aiiy aaieoeeo oa eaa?oeaoeio. Aaoi?
naiino?eii i?iaiaeeea oeeoieia?/i?, oeeoio?i?/i? oa iiey?ia?ao?/i?
aeine?aeaeaiiy AAC ianoaaeaieo oai?eo i?e aini?oae?caoe??, ia 10-e
aeaiue e?eoaaiiy oa i?e aeaooo? c? noaoe?iia?o, i?eeiaea o/anoue o
i?iaaaeaii? eiiieaenieo aeine?aeaeaiue ?ioiiiai noaoono. Iniaenoi
cae?enithaaeiny aeeiai?/ia niinoa?aaeaiiy oai?eo i?ioyaii onueiai
ia??iaeo noaoe?iia?iiai e?eoaaiiy. Aaoi?ii i?iaaaeaia noaoenoe/ia
ia?iaea ?acoeueoao?a ee?i?/ieo, ?ioiieia?/ieo, oeeoieia?/ieo oa
a?io?i?/ieo iieaciee?a.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe aeine?aeaeaiiy
aeeth/ai? aei ?a?no?o aaeocaaeo iiaiaaaaeaiue Oe?a?ie (aei. 8–9,
1999 ?.), aeiaaaeai? ia iaoeiai-i?aeoe/i?e eiioa?aioe?? “I?iaeaie ?
ia?niaeoeae ?icaeoeo ee?i?ee aioo??oi?o oai?ia” (i. Oa?e?a, 1995 ?.), ia
THa?eaei?e iaoeiai-i?aeoe/i?e eiioa?aioe??, i?enay/ai?e 100??//th
i?nueei? e?ea?i? ? 4 i. Eoaainueea (i. Eoaainuee, 1995 ?.), ia
V Anaoe?a?inuee?e ia?aae? c ieoaiue iie?ee?i?/ii? ni?aae
(i. Aei?i?iiao?ianuee, 1996 ?.), ia II c’?cae? ooec?ao??a ?
ioeueiiiieia?a Oe?a?ie (i. Ee?a, 1998 ?.).

No?oeoo?a e ianya aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 138 noi??ieao
iaoeiiieno ? aeeth/a? anooi, iaeyae e?oa?aoo?e, iien iaoa??ae?a ?
iaoiae?a aeine?aeaeaiiy, 3 ?icae?ee aeanieo aeaieo ? aeniiaee. Ia?ae?e
aeei?enoaieo aeaea?ae i?noeoue 169 a?o/eciyieo oa 190 ?iicaiieo
e?oa?aoo?ieo iineeaiue. Iaoa??aee aeena?oaoe?? ?ethno?iaai? 23
oaaeeoeyie, 18 ?enoieaie ? 14 ee?i?/ieie niinoa?aaeaiiyie.

INIIAIEE CI?NO

Iaoa??aee ? iaoiaee aeine?aeaeaiiy. Niinoa??aaeeny 122 oai?eo ia OIA,
ye? i?ioiaeeee eo?n e?eoaaiiy a ioeueiiiieiai/ieo a?aeae?eaiiyo iaeanii?
ee?i?/ii? e?ea?i? oa i?nueei? e?ea?i? ? 7 i. Eoaainueea a ia??iae c 1995
ii 1998 ?. Na?aae oai?eo ia?aaaaeaee /ieia?ee (59,0 %), aeii?ioaaea
a?eiaa a?oia iica 40 ?ie?a. Ia?aaaaeia a?eueo?noue aeine?aeaeoaaieo
oai?eo ia OIA no?aaeaeaee ia oea caoai?thaaiiy iiiaae 15 ?ie?a ?
ia?aianee ca inoaii? 3 ?iee a?eueoa 3 caaino?aiue; 84 oai?eo ia OIA
no?aaeaeaee oaeiae ia ??ciiiai?oi? oi?ie ?ON. O 16 c ieo caoai?thaaiiy
aoei aa?eo?eiaaii a noaoe?iia?? (o 9 /ieia?e aoa aeyaeaiee aeeoociee
ea?ae?ineea?ic, o 7 – noaa?eueia noaiiea?ae?y iai?oae). Ca ee?i?/ieie
aeaieie, a oaeiae ca ?acoeueoaoaie eaai?aoi?ieo, ooieoe?iiaeueieo ?
?aioaaiieia?/ieo iaoiae?a aeine?aeaeaiiy I noaae?y OIA aoea aa?eo?eiaaia
o 11,5 %, II – o 80,3 % ? III – o 8,1 % oai?eo. ??ci? oi?ie ?ON
aa?eo?eoaaee, aacoth/enue ia aeaieo AEA, aeaieo niinoa?aaeaiiy ai?noo
oieanoa?eio oa e?iii?ioa?ae?a o ne?iaaooe? e?ia?, aeaieo aaeia?aiiao???
oiui (inoaiiy i?iaiaeeeany a aeayeeo aeiaaeeao, ca iio?aaith).

Ianoaaeai? oai?? ia OIA aoee ?iciiae?eai? ia aea? a?oie, iaeii??aei? ca
a?eii, noaooth, oyaee?noth oa o?eaae?noth caoai?thaaiiy: ? a?oia – o?,
ui no?aaeaeaee ia OIA aac noiooiuei? iaoieia?? na?oeaai-noaeeiii?
nenoaie (38 /ieia?e), ? ?? a?oia – o?, ui no?aaeaeaee ia OIA o
noeoiiino? c ?ON (84 /ieia?ee). C iaoith aeine?aeaeaiiy aoaeoeaiino?
aioeieneaeaioii? oa?ai?? oai?? ia OIA ?c noiooiueith ?ON ca aeiaaeeiaith
iciaeith aoee ?iciiae?eai? ia o?e i?aea?oie, iaeii??aei? ca a?eii,
noaooth, oyaee?noth ? o?eaae?noth caoai?thaaiiy. Oai?? 1? i?aea?oie
(36 /ieia?e) io?eioaaee o?eueee aacenio oa?ai?th c o?aooaaiiyi
noiooiueiai caoai?thaaiiy; oai?? 2? i?aea?oie (22 /ieia?ee) io?eioaaee
aeiaeaoeiai aei eiiieaeniiai e?eoaaiiy aaieoee a aeiaia?e aeic? 500 ia o
2 i?eeiie, ii/eiath/e c 4–6 aeiy e?eoaaiiy, o?eaae?noue eo?no e?eoaaiiy
aei??aithaaea 14 aei?a; o oai?eo 3? i?aea?oie (26 /ieia?e) e?eoaaiiy OIA
aoei aeiiiaiaii eaa?oeaoeiii o e?ea?nuee?e oi?i? eaa?oeaoei-iaineio, ui
aaeeaaee ii 40 ia aeoeaii? ?a/iaeie o 2 i?eeiie, eo?n e?eoaaiiy
i?aia?aoii oaeiae aei??aithaaa 14 aei?a. sse ? aaieoee, eaa?oeaoei
i?ecia/aee i?ney 4–6 aei?a ao?io?iiii? oa?ai??. On? oai?? ia?aiineee
e?eoaaiiy caaeia?eueii, ia iii?/aii aeiaeiiai aeiaaeeo iaia?aiineiino?
aeaiiai i?aia?aoo.

Ee?i?/ia ianoaaeaiiy oai?eo aeeth/aei aea/aiiy nea?a, aiaiianoe/ieo
aeaieo, aeyaeaieo o?ce/ieie iaoiaeaie ci?i. Aiae?coaaeeny oaeiae aeai?
eaai?aoi?ieo aeine?aeaeaiue: ee?i?/iiai aiae?co e?ia?, aeoeaiino?
aino?ioaciaeo ?aaeoe?e, aiae?co oa?eioeiiy. An? oai?? aoee ianoaaeai?
?aioaaiieia?/ieie iaoiaeaie (i?iaiaeeeany ?aioaaiia?ao?y o aeaio
i?iaeoe?yo, ca iieacaiiyie – a?iioia?ao?y ? oiiia?ao?y). Ooieoe?th
ciai?oiueiai aeeoaiiy aecia/aee ca aeiiiiiaith aia?aoa “Iiaaiine?ei”
ae?iaieoeoaa I?ia//eie; i?e oeueiio ie?aii iae?/oaaeeny iano?oeoeaiee,
?ano?eeoeaiee ? ci?oaiee oeie aaioeeyoe?eii? iaaeinoaoiino?.

Aeine?aeaeaiiy ee?oeiieo iieaciee?a ?ioi?oaoo (e?euee?noue O- ?
Ae?ioioeeo?a, Ooaeia??a/?iaeoeoi??a ? Onoi?ani??a/e?ea??a) i?iaiaeeee
oeeoioiene/iei iaoiaeii (O?ieia A.I. ?c ni?aaao., 1989), aeei?enoiaoth/e
iiiieeiiaeuei? aioeo?ea o??ie Ortho Diagnostic Systems Inc. (USA) eean?a
CD3, CD4, CD8, CD22, c ia/eneaiiyi ?ioii?aaoeyoi?iiai ?iaeaeno
CD4 / CD8. Ne?iaaoeia? eiioeaio?aoe?? g A, Ig M, Ig G aei??thaaee
iaoiaeii ?aae?aeueii? ?ioiiaeeooc?? (*a?iooaiei E.O., 1997). ??aaiue ?
iieaeoey?iee neeaae oee?eoethth/eo ?ioiieo eiiieaen?a (Oe?E) (aaeeei-,
na?aaeiuei-, oa ae??aiiiieaeoey?i? o?aeoe??) aecia/aee iaoiaeii
aeeoa?aioe?eiaaii? i?aoeei?oaoe?? a 2 %, 3,5 % ? 6 % iie?ao?eaiae?eie? c
iieaeoey?iith ianith 6000 aeaeueoii (O?ieia A.I. ?c ni?aaao., 1986).

A?iioineii?/ii ae?aaiinooaaeany oi?ia aiaeia?iio?oo (iaiaaeaiee,
aeeoociee, eaoa?aeueiee, ai?eiee), a oaeiae iioe?ai?noue ? nooi?iue
aeoeaiino? caiaeaiiy ca e?eoa??yie A.?. Eoeiinueeiai (1982). Iaaeae? i?e
aiae?c? ee?i?/ieo oa oeeoieia?/ieo ia?aiao??a ioe?ithaaee ee?i?/io
aeoeai?noue caiaeueiiai i?ioeano (A?iaiaa I.I. ?c ni?aaao., 1991).

A i?ioean? o?a?ia?iioineii?/iiai aeine?aeaeaiiy, eio?a i?iaiaeeeiny i?e
aini?oae?caoe??, ia 10-e aeaiue e?eoaaiiy oa i?e aeaooo? c? noaoe?iia?o,
cae?enithaaee a?aea?? AAC. Aeine?aeaeoth/e cieae, aecia/aee aaniethoio
e?euee?noue ee?oei, neeaaeaee oeeoia?aio a?iioiaeueaaiey?iiai i?inoi?o,
ioe?ithaaee aeeoo?caeaoi?noue aeueaaiey?ieo iae?ioaa?a (AI) oa ee?oei
a?iio?aeueiiai ai?oae?th (AA) ca aeiiiiiaith oanoo ia aeeeth/aiiy
o?eiaiiaiai neiueiai, aecia/aee aeoeai?noue eeniaaicaeaaeieo iaoai?ci?a
e?e?iao AI ca ?acoeueoaoaie oanoo ia a?aeiiaeaiiy i?o?ineiueiai
oao?acie?th (INO-oanoo), a oaeiae iayai?noue noeoeeiaoaeaa?ae?iaaiacii?
aeoeaiino? (NAeA) ai?oae?ioeeo?a. E??i oiai iiey?ia?ao?/iei iaoiaeii
aei??thaaee ai?no a AAC aeoeaiaaieo oi?i eenith (AOE), cie?aia
a?ae?ieneeueieo ?aaeeeae?a, aeoeaiaaiiai eenith ? ia?aeenieo niieoe, ui
? ?ioaa?aeueiei iieacieeii aaeaino “IIE–AIC” a?iioiaeueaaiey?iiai
i?inoi?o. Eiio?ieueio a?oio neeaee 25 i?aeoe/ii caei?iaeo in?a, o yeeo
aoei aeine?aeaeaii noai i?noeaaiai caoenoo e aioeieneaeaioii? nenoaie.
Eiio?ieuei? aaee/eie iieaciee?a, eio?? oa?aeoa?ecothoue nenoaio
?ioi?oaoo, aoee io?eiai? a i?aeeaoaae?aeuei?e iaoeiai-aeine?aei?e
eaai?aoi??? Eoaainueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.

Aeey noaoenoe/ii? ioe?iee ?acoeueoao?a aeine?aeaeaiiy aeei?enoiaoaaee
ia?aiao?e/iee te?eoa??e Nouethaeaioa – O?oa?a; ei?aeyoe?th i?ae
ee?i?/ieie i?iyaaie caoai?thaaiiy ? aeaieie aeine?aeaeaiiy noaio
i?noeaai? ianiaoeeo?/ii? ?acenoaioiino? ioe?ithaaee ca aeiiiiiaith
ia?iiai eiao?oe??ioa ?aiaiai? ei?aeyoe?? rS Ni??iaia. Ia/eneaiiy
i?iaiaeeee ia ia?niiaeueiiio eiii’thoa?? ca aeiiiiiaith iaeaoa Mathcad 7
Professional (MathSoft Inc. 1997).

Ee?i?/ia oa?aeoa?enoeea ianoaaeaieo oai?eo. An? ianoaaeai? oai??
ia?aaoaaee ia e?eoaaii? a noaoe?iia?? o ia??iae caaino?aiiy
caoai?thaaiiy. Ee?i?/ia ea?oeia caoai?thaaiiy o oai?eo ia OIA o
noeoiiino? c ?ON oa?aeoa?ecoaaeany ae?aaeaiei neiae?iiii aca?iiiai
iaoyaeaiiy. Aiaeii/an o oai?eo aeaii? a?oie iii?/aeany iaio ae?aaeaia
i?iiania ?aaeoe?y, iaee i?noea iaio? ci?ie a aaiia?ai? e aino?ioacia?
?aaeoe??. Uiaei ia?aa?ao OIA o oai?eo aac noiooi?o caoai?thaaiue
na?oeaai-noaeeiii? nenoaie ? c? noiooiueith ?ON iaea?eueo cia/ia
??cieoey aoea aeyaeaia i?e aiae?c? i?iya?a aeeoaeueii? iaaeinoaoiino?
(AeI). Oae, AeI III nooiaiy aoea aeyaeaia o 23,8 % oai?eo I a?oie ? o
39,8 % oai?eo ? i?aea?oie ?I a?oie. Ia a?aei?io a?ae oai?eo I a?oie, o
yeeo niinoa??aaeany i?yia caeaaei?noue oyaeeino? aaioeeyoe?eieo
ii?ooaiue a?ae aeoeaiino? caiaeaiiy, o oai?eo ia OIA o noeoiiino? c ?ON
aeeoaeueia iaaeinoaoi?noue aeuiai nooiaiy noi?iaiaeaeoaaeany iaioith
aeoeai?noth caiaeueiiai i?ioeano. O aeaii? a?oie oai?eo /ano?oa
aeyaeyeeny iciaee aio?caie eaaai?a, iiaaiio?a?ico ? aoi?eiii? eaaaiaai?
a?ia?oaic??. Aei oiai ae caaino?aiiy OIA iaoyaeoaaei ia?aa?a ?ON: o 19
/ieia?e iii?/aeeny iaiaaee noaiiea?ae??, o ?ioeo i?e
aeaeo?iea?ae?ia?ao?/iiio aeine?aeaeaii? aeyaeyeeny ??cii? ae?aciino?
ii?ooaiiy i?ioean?a ?aiiey?ecaoe?? a i?iea?ae?. Iaaeinoaoi?noue
e?iaiia?ao I–IIA noaae?e aoea ae?aaiinoiaaia o iieiaeie ianoaaeaieo.
Aeaeo?iea?ae?ia?ao?/ia aeine?aeaeaiiy aeyaeyei ii?ooaiiy ?eoio o
aeaeyae? oeoii/eiai? aeno?anenoie?? (o 14 oai?eo) oa ieaioeeai? a?eoi??
(o 7 oai?eo). A?io?i?/ia aeine?aeaeaiiy e?ia? aeyaeyei
a?ia?oieanoa?eiai?th o 24 oai?eo, iciaee a?ia?eiaaoeyoe?? – o 13,
i?eai?/aiiy o?a?eiie?co – o 9.

A i?ioean? e?eoaaiiy iiceoeaia aeeiai?ea o oai?eo 1? i?aea?oie ?? a?oie
iaea iaio ae?aaeaiee oa?aeoa?, i?ae a I a?oi?: a?eueoa aoei oaeeo, o
eiai i?e aeaooo? c? noaoe?iia?o niinoa??aaeeny eaoaeue, caeeoeia? yaeua
caiaeueiiai i?ioeano a a?iioao, i?iyae anoaii-aaaaoaoeaiiai neiae?iio
oiui. C? noaoe?iia?o oai?? aeaoaaee i?ney eoi??oaaiiy caaino?aiiy OIA,
i?ioa i?aeoe/ii o an?o ieo caeeoaeeny cieaeaia oiea?aioi?noue aei
o?ce/iiai iaaaioaaeaiiy, caaeeoea aeni??aoi?iiai aai ci?oaiiai
oa?aeoa?o, iii?/aeany neaaei ae?aaeaia iiceoeaia aeeiai?ea i?iya?a ?ON.
I?ney aeaoooy c? noaoe?iia?o an? oai?? i?iaeiaaeoaaee aiaoeaoi?ii
io?eioaaoe ea?ae?io?iiio oa?ai?th, o?i? c ieo i?ioyaii 1 i?nyoey aoee
aini?oae?ciaai? aei ea?ae?ieia?/iiai noaoe?iia?o, 14 /ieia?e i?ioyaii 6
i?nyoe?a – iiaoi?ii aei ioeueiiiieia?/iiai a?aeae?eaiiy a ca’yceo c
caaino?aiiyi OIA.

Noai ?ioi?oaoo ? i?noeaai? aioe?ioaeoe?eii? ?acenoaioiino? o oai?eo ia
OIA o noeoiiino? c ?ON. Aea/aiiy ?ioiiiai noaoono oai?eo ia OIA o
ia??iae caaino?aiiy caoai?thaaiiy, a oaeiae i?ney aeinyaiaiiy ?ai?n??,
aeyaeyei ?noioi? a?aeoeeaiiy oaeiai a?ae aiaeia?/ieo iieaciee?a
i?aeoe/ii caei?iaeo in?a. C aieo ee?oeiii? eaiee ?ioi?oaoo aoei
anoaiiaeaia no?eea nei?i/aiiy oioaeueii? iiioeyoe?? Oe?ioioeeo?a (CD3),
ui a?aeaoaaeiny ye ca ?aooiie a?aeiinii? e aaniethoii? e?eueeino?
oaeia??a/?iaeoeoi??a (CD4), oae ? ca ?aooiie a?aeiiniiai ai?noo
noi?ani??a/e?ea??a (CD8). Cacia/aia ni?aa?aeiioaiiy /enaeueiino?
noaiiioeyoe?e Oe?ioioeeo?a ciaeoei a?aeaeoie o ci?i? ?ioii?aaoeyoi?iiai
?iaeaeno (CD4 / CD8). Inoaii?e aoa no?eei cieaeaiei i?ioyaii onueiai
ia??iaeo ia?aaoaaiiy oai?eo a noaoe?iia?? ? ia aeinyaaa aaee/eie
eiio?ieueii? a?oie i?e aeaooo?. Iienai? ci?ie aoee ?icoe?iai? iaie ye
iane?aeie oi?ioaaiiy o oai?eo ia OIA noi?ani?iiai aa??aioa aoi?eiiiai
?ioiiaeao?oeeoiiai noaio. O iaioiio nooiai? caaino?aiiy OIA a?aeaeaaeiny
ia noai? Aee?oeiiiai ?ioi?oaoo: a?aeiinia /enei Ae?ioioeeo?a (CD22) o
oeeo oai?eo ia a?ae??ciyeiny a?ae oaeiai o i?aeoe/ii caei?iaeo in?a, a
aaniethoia – aoei eeoa aeae?eueea iaioei ia iiiaio aini?oae?caoe?? ?
i?aeoe/ii ia ci?ithaaeiny iaaeae?. Aeine?aeaeaiiy aoii?aeueii? eaiee
?ioi?oaoo aeyaeyei aeinoia??ia cieaeaiiy ai?noo Ig A a ii/aoeiaiio
ia??iae? caaino?aiiy, yea i?e aeaooo? c? noaoe?iia?o iiaa?oaeiny aei
ii?iaeueii? aaee/eie. Ai?no Ig G, iaaiaee, aoa i?aeaeuaiei i?e
aini?oae?caoe??, ua a?eueo c?inoath/e aei iiiaioo aeaoooy c?
noaoe?iia?o. Aeinoia??ieo ci?i ai?noo Ig M iii?/aii ia aoei.
Eiioeaio?aoe?y Oe?E ia?aaeuoaaea eiio?ieuei? aaee/eie a 1,5 ?ace i?e
aini?oae?caoe?? ? a 1,4 ?ace – i?e aeaooo? c? noaoe?iia?o, ?c
ia?aaaaeaiiyi na?aaeiuei- oa ae??aiiiieaeoey?ii? o?aeoe?e (a?aeiiniee
ai?no inoaii?o i?e aini?oae?caoe?? aoa ca?eueoaiei a 1,9 ? 2,9 ?ace, a
ia iiiaio aeaoooy – a 1,7 ? 2,5 ?ace a?aeiia?aeii).

Caaino?aiiy OIA o oai?eo ?c noiooiueith ?ON noi?iaiaeaeoaaeiny a?eueo
?noioieie ci?iaie iniiaieo iieaciee?a nenoaiiiai ?ioi?oaoo. Oae,
aeyaeyeany cia/i?oa Oe?ioiiai?y: /enaeuei?noue o?aeoe?? CD3 i?e
aini?oae?caoe?? aei??aithaaea 0,93±0,02×109 ee/e (o oai?eo ia OIA, ui ia
no?aaeaeaee ia ?ON, – 1,15±0,03×109 ee/e, a eiio?ieuei?e a?oi? –
1,60±0,05×109 ee/e, P<0,05). Aeenaaeain i?ae noaiiioeyoe?yie Onoi?ani??a/e?ea??a (CD8) ? Ooaeia??a/?iaeoeoi??a (CD4) aoa oaeiae cia/i?oei, aiane?aeie /iai ?ioii?aaoeyoi?iee ?iaeaen neeaaeaa o oeeo oai?eo i?e aini?oae?caoe?? 1,37±0,10 (a I a?oi? – 1,69±0,08, a eiio?ieuei?e a?oi? – 2,20±0,08, P<0,05) ? i?e aeaooo? c? noaoe?iia?o caeeoaany i?aeoe/ii iaci?iiei. ?aaeoe?y aoii?aeueii? eaiee ?ioi?oaoo oa?aeoa?ecoaaeany ciaioaiiyi a i?ioean? e?eoaaiiy ai?noo a e?ia? Ig A (i?e aini?oae?caoe?? – 1,50±0,07 a/e, i?e aeaooo? – 1,07±0,07 a/e, a eiio?ieuei?e a?oi? – 1,40±0,08 a/e, P<0,05) ? cia/i?oei i?aeaeuaiiyi ??aiy Ig G (17,76±0,67 a/e o oai?eo ia ?ON; 16,19±0,62 a/e o oai?eo, ui ia no?aaeaeaee ia ?ON; 10,20±0,50 a/e o i?aeoe/ii caei?iaeo in?a, P<0,05). Ai?no Oe?E a e?ia? oaeiae aoa a?eueo aenieei, c? ci?iith ni?aa?aeiioaiiy ia ei?enoue na?aaeiuei- oa ae??aiiiieaeoey?ieo o?aeoe?e (a?aeiia?aeii, 48,6±0,7 % oa 38,9±0,8 % a ii??aiyii? c 40,6±0,5 % oa 31,1±0,5 % o oai?eo aac noiooiuei? ?ON). O oai?eo ia OIA aac noiooiuei? ?ON ia ii/aoeo caaino?aiiy caoai?thaaiiy aeyaeyeiny naie?aciaa ca?eueoaiiy oeeoico AAC, yea caeeoaeiny a i?ioean? e?eoaaiiy, i?ioa a?aeiiniee ai?no AA aoa a 1,7 ?ace, a AI – oo?i? iaioei oaeiai o i?aeoe/ii caei?iaeo in?a (oaae. 1). A aeeiai?oe? e?eoaaiiy aeaneaaiaoe?y AA oa i?a?aoe?y aei a?iioiaeueaaiey?iiai i?inoi?o iaeo?io?e?a noaoenoe/ii cia/eii ciaiooaaeeny, ?ae?oooaaiiy AI aeae?eueea iineethaaeiny, niinoa??aaeiny ca?eueoaiiy /anoee AA ? AI o oeeoia?ai? ? ciaioaiiy – iaeo?io?e?a. Oa?aeoa?ii, ui ci?ie e?eueeino? AA iineee aeinoia??iee oa?aeoa? aaea ia 10e aeaiue e?eoaaiiy, o oie /an ye aeeiai?ea ?ioeo ia?aiao??a niinoa??aaeany eeoa i?ney eoi??oaaiiy caaino?aiiy caoai?thaaiiy. I?e c?noaaeaii? oeeoiii?oieia?/ieo aeaieo ?c ?acoeueoaoaie ee?i?/iiai aeine?aeaeaiiy oai?eo ia OIA ie iii?/aee aenieee nooi?iue ei?aeyoe?? i?ae iieacieeaie caaaeueiiai oeeoico e aeoeaiino? caiaeueiiai i?ioeano – i?e aini?oae?caoe?? oai?eo rS=0,93, a i?ioean? e?eoaaiiy rS=0,91 ? i?e aeaooo? c? noaoe?iia?o rS=0,95. –– – – O an?o oai?eo ia OIA a aino?iio ia??iae? caoai?thaaiiy niinoa??aaeiny cieaeaiiy aoaeoeaiino? ooieoe?iioaaiiy ee?oeiii? eaiee i?noeaai? ianiaoeeo?/ii? ?acenoaioiino? a?iio?a, naia iniiaieo ?? eiiiiiaio?a: ai?oae?aeueiiai aa?’??a iia?o?iiinieo oeyo?a ? AI. Ia oeueiio oe? ca?eueoaiiy ?ae?oooaaiiy AI iiaeia ?icaeyaeaoe ye iaoai?ci, ui eiiiaino? iaaeinoaoith ooieoe?iiaeueio aeoeai?noue aeaiiai ee?oeiiiai oeio. Oaeee aeniiaie i?aeoaa?aeaeo? iaaaoeaia ei?aeyoe?y (rS= 0,88) i?ae caaaeueiith e?euee?noth AI ? ai?noii INO-iiceoeaieo AI a oiae? e?eoaaiiy. O oai?eo ia OIA ?c noiooiueith ?ON niinoa??aaeany ae?aci?oa, i?ae o oai?eo I a?oie, aeaneaaiaoe?y AA ii?yae c aeaui a?eueoith /anoeith ee?oei a oeeoia?ai?, aeoeai?oa ?ae?oooaaiiy AI ? iaio ae?aaeaia i?a?aoe?y iaeo?io?e?a aei a?iioiaeueaaiey?iiai i?inoi?o. Ia a?aei?io a?ae a?oie ii??aiyiiy, aeyaeai? ii?ooaiiy aoee no?eeeie a i?ioean? e?eoaaiiy, a iiceoeaia aeeiai?ea – iacia/iith. Iii?/aia caeiiii??i?noue aeyaeyeany oaeiae o ee?i?ei–oeeoiii?oieia?/ieo ei?aeyoe?yo: o oai?eo ia OIA ?c noiooiueith ?ON iaeaeua iiceoeaia ei?aeyoe?y i?ae iieacieeaie caaaeueiiai oeeoico e aeoeaiino? caiaeueiiai i?ioeano niinoa??aaeany i?e aini?oae?caoe?? (rS=0,90), a oiae? e?eoaaiiy aiia ciaiooaaeany (rS=0,82) ? aeinyaaea i?i?ioio i?e aeaooo? c? noaoe?iia?o (rS=0,76). Ai?no AA ?c iayaiith aeoeai?noth NAeA a AAC oeeo oai?eo aoa cia/ii ieae/ei, i?ae o oai?eo a?oie ii??aiyiiy, oa a?aecia/aany i?i?iaeueiith aeeiai?eith a i?ioean? e?eoaaiiy. Ai?no INO-iiceoeaieo AI, i?e aini?oae?caoe?? aeaui ieae/ee, i?ae o oai?eo I a?oie, ia 10e aeaiue e?eoaaiiy i?iaeiaaeoaaa ciaiooaaoeny, ? i?e aeaooo? c? noaoe?iia?o ia aeinyaaa ??aiy ia?oiai aei??o. Iaaaoeaia ei?aeyoe?y i?ae caaaeueiith e?euee?noth AI ? ai?noii INO-iiceoeaieo AI aoea a?eueoith (rS= 0,92), i?ae a a?oi? ii??aiyiiy. Aeai? iiey?ia?ao?/iiai aiae?co AAC na?ae/eee i?i cieaeaio aoaeoeai?noue AIC o an?o aeine?aeaeoaaieo oai?eo ia OIA. O oai?eo ? a?oie i?aeaeuai? ??ai? AOE ?, iniaeeai, ia?aeenieo niieoe caeeoaeeny aei iiiaioo aeaoooy c? noaoe?iia?o, ui, iiaeeeai, na?ae/eoue i?i iaaeinoaoi?noue iaoa?iaioaoeaii? eaiee AIC. O oai?eo 1? i?aea?oie II a?oie aoei aeyaeaii a?eueo cia/ia cieaeaiiy aoaeoeaiino? aioeieneaeaioieo iaoai?ci?a, iii?/aeany aeua eiioeaio?aoe?y a AAC an?o AOE. I?e aeaooo? c? noaoe?iia?o caa??aaeiny ?noioia i?aeaeuaiiy an?o iiey?ia?ao?/ieo oaeeue. I/aaeaeii, iaaeoi cia/ia aeoeaaoe?y ia?aeeniiai ieenethaaiiy e?i?ae?a i?e OIA o noeoiiino? c ?ON noi?iaiaeaeoaaeany i?iaeoeoe??th oaei? e?eueeino? iaoaaie?o?a ia?aeeniiai ieenethaaiiy iaia?aiieo no?oeoo? ee?oei, yea ia?aaeuoaaea eaoae?oe/io caeaoi?noue aioeieneaeaioieo oa?iaio?a; ioaea oaeee noai iiaeeeai ?icoe?ithaaoe ye iani?iiiaei?noue an??? nenoaie AIC (oaae. 2). O oai?eo iaio a?oi ia an?o aoaiao oai?iae niinoa??aaeany aeniea iiceoeaia ei?aeyoe?y i?ae nooiaiai aeeoaeueii? iaaeinoaoiino? ? ??aiai AOE a AAC (rS aei??aithaaa, a?aeiia?aeii, 0,94 ? 0,95 i?e aini?oae?caoe??; 0,92 ? 0,95 a oiae? e?eoaaiiy; 0,94 ? 0,96 ia iiiaio aeaoooy c? noaoe?iia?o). I/aaeaeii, cia/i? iano?oeoeai? ii?ooaiiy o oeeo oai?eo ni?e/eithaaee i?eai?/aiiy nenoaie AIC, iacaeaaeii a?ae i?iaaaeaieo e?eoaaeueieo caoiae?a oa ee?i?ei-aiaeineii?/iiai noaio. –––– – – Oi/a, ca ee?i?ei-?ino?oiaioaeueieie e?eoa??yie, o?aaeeoe?eia e?eoaaiiy iie?auoaaei noai oai?eo, i?ioa ia o?eueee ia iiiiaethaaei ooieoe?iiaeueii? ni?iiiaeiino? nenoaie AIC, aea ? ia oiia?eueithaaei i?ia?anoth/i? ?? aeaeiiiainaoe??. Aeaiee aeniiaie i?aeoaa?aeaeoaaei aeyaeaiiy a a?oi? oai?eo ia OIA o noeoiiino? c ?ON a?eueo oyaeeeo oi?i aeeoaeueii? iaaeinoaoiino?. O oeeo oai?eo oaeiae niinoa??aaeany neaaea iiceoeaia aeeiai?ea an?o ?icaeyiooeo ia?aiao??a AIC. Ii??aiyeueiee aiae?c aoaeoeaiino? aaieoeeo ? eaa?oeaoeio o oai?eo ia OIA c? noiooiueith ?ON. Ii??aiyiiy oa?aiaaoe/ieo aoaeo?a aaieoeeo ? eaa?oeaoeio aeyaeei, ui i?e aeecueeeo ee?i?/ieo aoaeoao i?aia?ao?a uiaei ia?aa?ao OIA, eio?? ae?aaeaeeny ia?aaaaeii ciaioaiiyi oyaeeino? iano?oeoeaiiai neiae?iio oa aeinyaiaiiyi a?eueo o?eaei? ?ai?n??, canoinoaaiiy eaa?oeaoeio coiiaethaaei oaeiae ni?eyoeea?oee ia?aa?a ?ON – ??aeoaee iaiaaee noaiiea?ae??, iie?ioeany iaoaaie?ci i?iea?aea ca aeaieie AEA, i?aeaeueeany oiea?aioi?noue aei o?ce/iiai iaaaioaaeaiiy. Ana oea ?iaeoue canoinoaaiiy eaa?oeaoeio a?eueo aaaeaiei i?e e?eoaaii? OIA o noeoiiino? c ?ON. O a?aeiioaii? noaio i?noeaaiai caoenoo a?iio?a ne?ae cacia/eoe ia?aaaao aaieoeeo uiaei noeioethth/iai aieeao ia iaoaaie?ci AA, a naia i?aeaeuaiiy aeeoo?caeaoiino? ee?oei ? ciaioaiiy ?ioaineaiino? aeaneaaiaoeaieo i?ioean?a a iane?aeie aaeeaaiiy i?aia?aoo (?en. 1). A ii??aiyii? c aaieoeeii, ei?eaoaaeueiee aoaeo eaa?oeaoeio aoa aeaui iaio ae?aaeaiei o a?aeiioaii? AA, i?ioa aeinyaaeany cia/i?oa aeoeaaoe?y eeniaaicaeaaeieo iaoai?ci?a aaeoa?eoeeaeiino? AI. O eaa?oeaoeio aeii?ioaaa iiceoeaiee aieea ia aeeoo?caeaoi?noue ? eeniaaee iaoaaie?ci AI. Aiaeii/an niinoa??aaeiny oaeiae ae?aaeaia ciaioaiiy i?ae ae??th i?aia?aoo i?a?aoe?? aei a?iioiaeueaaiey?iiai i?inoi?o iaeo?io?e?a, ui, iaiaaia, a?aeaeaa? i?ioecaiaeueiee aoaeo. Aieeaia?oith aeyaeyeany aioeieneaeaioia ae?y aaieoeeo: ciaioaiiy ai?noo a AAC an?o iniiaieo eean?a AOE, iiaeeeai, noaei a?aeaeoeii ii?aeiaiiy i?yiiai ? iai?yiiai aioeieneaeaioieo aoaeo?a i?aia?aoo (?en. 2). Aioeieneaeaioi? aeanoeaino? eaa?oeaoeio aeyaeyeeny ia?aaaaeii o?ainoi?iaoe??th iaea?eueo oiene/ieo a?ae?ieneeueieo ?aaeeeae?a ? aeoeaiaaiiai eenith a iaio aeoeai? ia?aeeni? niieoee, eio??, i?ioa, iathoue ieenethaaeuei? aeanoeaino?, ui iaa?oioiao? ia?aaaao a iueiai i?yii? aioeieneaeaioii? aeoeaiino?. Cacia/aia iniaeea?noue ?iaeea oa?iaeiaeeiai?eo eaa?oeaoeio a oeueiio iai?yieo aeae?eueea iaio aoaeoeaiith, i?ae o aaieoeeo. AENIIAEE 1. Iniaeeainoyie ee?i?/ieo i?iya?a OIA o oai?eo ia ?ON ? iaea aeoeai?noue caiaeueiiai i?ioeano, ?icaeoie a i?ioean? e?eoaaiiy ae?aciiai ? no?eeiai a?iioiiano?oeoeaiiai neiae?iio, ?acenoaioi?noue aei aaeeaaiiai e?eoaaiiy, /ano? ?aoeeaeeae. A ia??iae caaino?aiiy OIA ia?aa?a ?ON oa?aeoa?eco?oueny iii??iith ae?aci?noth, i?ieea?noth oa /anoei ?aoeeaeeaoaaiiyi aieueiaiai ea?ae?aeueiiai neiae?iio, ui iio?aao? o?eaaeiai canoinoaaiiy i?o?ao?a ? aeieaoi??a eaeueoe??aeo eaiae?a, aeieeiaiiyi ii?ooaiiy o?io?/ieo i?ioean?a a na?oeaaiio i’yc?, a oaeiae ?aa?an??th iniiaieo i?iya?a caoai?thaaiue i?ney eoi??oaaiiy caaino?aiiy OIA. 2. O oai?eo ia OIA aeyaeythoueny ii?ooaiiy a ee?oeii?e ? aoii?aeuei?e eaieao ?ioi?oaoo, ye? oa?aeoa?ecothoueny Oe?ioiiai??th, aoi?eiiei ?io-iiaeao?oeeoiei noaiii noi?ani?iiai oeio, cieaeaiiyi eiioeaio?aoe?? Ig A, Ig M, Ig G, no?eeei ca?eueoaiiyi ai?noo a e?ia? Oe?E, ia?aaaaeii ca ?aooiie na?aaeiueiiieaeoey?ieo ? ae??aiiiieaeoey?ieo o?aeoe?e. I?e ?icaeoeo OIA ia oe? ?ON cacia/ai? ii?ooaiiy a?eueo cia/i?, ?i i?eoaiaia ?iaa?nia aeeiai?ea ai?noo a e?ia? Ig A oa ae??aiiiieaeoey?ieo o?aeoe?e Oe?E. 3. O oai?eo ia OIA aeyaeaii i?eai?/aiiy ooieoe?iiaeueii? aeoeaiino? iniiaieo ee?oeiieo /eiiee?a ianiaoeeo?/ii? ?acenoaioiino? a?iio?a, yea noi?iaiaeaeo?oueny eiiiainaoi?iei iineeaiiyi aeaneaaiaoe?? AA, ?ae?oooaaiiy AI oa i?a?aoe?? iie?ii?oiiyaea?ieo eaeeioeeo?a ia?eoa?e/ii? e?ia? aei a?iioiaeueaaiey?iiai i?inoi?o ? ii?aeio?oueny c iaeiie/aiiyi o a?iioiaeueaaiey?iiio i?inoi?? ?ioa?iaae?ao?a a?aeiiaethaaiiy eenith, ui ? a?aeaeoeii iani?iiiaeiino? nenoaie i?noeaaiai aioeieneaeaioiiai caoenoo. 4. I?e noi?niaii? OIA ?c ?ON o oioiaei? oace oai?iae iii?/athoueny ae?aci?o?, i?ae o oai?eo ia OIA aac noiooi?o caoai?thaaiue, iineeaiiy aeaneaaiaoeaieo i?ioean?a o neecia?e iaieiioe? a?iio?a, ?ae?oooaaiiy AI, ciaioaiiy i?a?aoe?? aei a?iioiaeueaaiey?iiai i?inoi?o iie?ii?oiiyaea?ieo eaeeioeeo?a, i?eai?/aiiy aeeoo?caeaoiino? ? iaoaaie?/ii? aeoeaiino? AA oa AI, aeenaaeain o nenoai? “IIE–AIC”; ca oiia o?aaeeoe?eii? oa?ai?? ii?ooai? iieacieee o oeeo oai?eo caciathoue i?i?iaeueii? iiceoeaii? aeeiai?ee, /ei aecia/a?oueny iano?ee?noue ?ai?n?? OIA. 5. Aeiaeaoeiaa aaeeaaiiy aaieoeeo ? eaa?oeaoeio a eiiieaeniiio e?eoaaii? oai?eo ia OIA o noeoiiino? c ?ON ni?ey? a?eueo aenieiio oaiio eoi??oaaiiy caiaeueiiai i?ioeano oa a?aeiiaethaaiiy ii?ooaieo aaiaoieia?/ieo iieaciee?a, ciaioaiith i?iya?a aeeoaeueii? iaaeinoaoiino?, ca?eueoo? o?eaae?noue ?ai?n?? caoai?thaaiiy. 6. Canoinoaaiiy aaieoeeo ? eaa?oeaoeio a eiiieaeniiio e?eoaaii? oai?eo ia OIA o noeoiiino? c ?ON ni?ey? a?eueo iiaiiio, i?ae o oai?eo, ye? io?eiothoue o?aaeeoe?eia e?eoaaiiy, a?aeiiaeaiith ii?ooaieo iieaciee?a i?noeaai? ianiaoeeo?/ii? ?acenoaioiino? a?iio?a: a) i?ae aieeaii aaieoeeo cieaeo?oueny ooai?aiiy oeeoioiene/ieo iaoaaie?o?a IIE a a?iio?aeueiiio aea?aa?, ui ? i?iyaii ye i?yii?, oae ? iai?yii? aioeieneaeaioii? ae??; oeeoii?ioaeoi?i? aeanoeaino? i?aia?aoo iayai? ia?aaaaeii a ai?oae?? neeciai? iaieiiee a?iio?a – aeoeaothoueny iaoaaie?/i? i?ioeane a AA, i?aeaeuo?oueny aeeoo?caeaoi?noue ee?oei, ciaioo?oueny ?ioaineai?noue aeaneaaiaoeaieo i?ioean?a; a) eaa?oeaoei ni?ey? ?iaeoeaaoe?? AOE a a?iio?aeueiiio aea?aa?, ui ? a?aeaeoeii ia?aaaaeii i?yiiai aioeieneaeaioiiai aoaeoo i?aia?aoo, aieea eio?iai ia ee?oeii? /eiieee ianiaoeeo?/ii? ?acenoaioiino? a?iio?a i?iyaey?oueny aieiaiei /eiii i?aeaeuaiiyi aeeoo?caeaoiino? e aeoeaaoe??th eeniaaicaeaaeieo iaoai?ci?a aaeoa?eoeeaeiino? AI. IA?AE?E IAOEIAEO IOAE?EAOe?E CAeIAOAA*A CA OAIITH AeENA?OAOe?? 1. Iooeioeaa A.E., Aeo?euae A.ss. Nunieeeia O.A., Oia?oe A.N., Iiiia I.A.,O?ai/aiei N.I., Aeieeineay I.A., Noaiaiaiei O.E., Naaeia A.E., ?acoiiay O.A.,Yiooaei A.N. Yeieiae/aneea aniaeou iaoiaaiaca ianiaoeeoe/aneeo caaieaaaiee eaaeeo. // Oe?aiinueeee ioeueiiiieiai/iee aeo?iae.– 1996.– ? 2.– C. 43–46. 2. Iooeioeaa A.E., Aeieeineay I.A., Ia/eoaeeiaa A.N. Eiioiiay ?aaeoeaiinoue i?aaiecia e ianiaoeeoe/aneay ?acenoaioiinoue a?iioia i?e caoyaeiii oa/aiee ino?ie iiaaiiiee // Oai aea.– 1998.– ? 1. C. 31–33. 3. Aeieeinueea I.A. Aoaeoeaiinoue eaa?oeaoeio a eiiieaeniiio eieoaaiii oai?eo ia o?iie/iee iano?oeoeaiee a?iioio // Oe?ainueeee iaaee/iee aeueiaiao.– 1998.– O. 1, ? 4.– N. 84–86. 4. Aeieeinueea I.A. Oaeoi?e inoeaaiai caoenoo o?aoaia?iioaeueiiai aea?aaa a oai?eo ia o?ii/iee iano?oeoeaiee a?iioo // Oai aea.– 1999.– O. 2, ? 1.– N. 28–32. 5. Iooeioeaa A.E., Aiaeyiee O.A., Aeieeineay I.A. Eiioiiua ia?ooaiey i?e caoyaeiii oa/aiee ino?ie iiaaiiiee o ?aaioieeia iieethoaioiaa?anneaiuo i?ioannee // Aeooaeueii i?iaeaie aeooa?noaa i aiiaeieiai, eeiii/ii iioiieiai oa iaaee/ii aaiaoeei / Ca. iaoeiaeo i?aoeue, aeione 2.– Eea–Eoaainuee, 1998.– N. 270–273. 6. Aeieeineay I.A. Aeoeaaoeey nenoaiu ianoiie caueou eaaeeo o aieueiuo o?iie/aneei iano?oeoeaiui a?iioeoii a ni/aoaiee n eoaie/aneie aieaciueth na?aeoea iiae aeeyieai aaieoeea  // Oai aea.– Aeione 3.– 1999.– N. 148–153. 7. Aeieeineay I.A., Ieioieeia TH.I. Ninoiyiea eeaoi/iuo oaeoi?ia ianiaoeeoe/aneie ?acenoaioiinoe o?aoaia?iioeeueiiai aea?aaa o aieueiuo o?iie/aneei iano?oeoeaiui a?iioeoii a ni/aoaiee n eoaie/aneie aieaciueth na?aeoea // Oai aea.– N. 153–156. 8. Aeieeinueea I.A. Noai ?ioi?oaoo o oai?eo ia o?ii?/iee iano?oeoeaiee a?iio?o o noeoiiino? c ?oai?/iith oai?iaith na?oey. // I?iaeaie aeieia?/ii? oa iaaee/ii? aaiaoeee ? ee?i?/ii? ?ioiieia?? / Ca. iaoeiaeo i?aoeue, aei. 1 (21).– Eoaainuee, 1999.– N. 127–134. 9. Iooeioeaa A.E., Aeo?euae A.ss., Nunieeeia O.A., O?ai/aiei N.I., Aeieeineay I.A., Oia?oe A.N., Noaiaiaiei O.E. Iaeioi?ua aniaeou iaoiaaiaca ianiaoeeoe/aneeo caaieaaaiee eaaeeo a oneiaeyo i?iiuoeaiiiai ?aaeiia Aeiiaanna // I?iaeaiu e ia?niaeoeau ?acaeoey eeeieee aioo?aiieo aieaciae / ?ani. na. iao/iuo o?oaeia.– Oa?ueeia, 1996.– N. 21–26. 10. Iooeioeaa A.E., Nunieeeia O.A., O?ai/aiei N.I., Oia?oe A.N., Aeieeineay I.A.,Noaiaiaiei O.E. I iaeioi?uo aii?inao yoaiiie yaiethoeee ianiaoeeoe/aneeo caaieaaaiee eaaeeo.– Oai aea.– N. 26–30. 11. Iooeioeaa A.E., Ieaieoeeay A.N., Oia?oe A.N., O?ai/aiei N.I., Caa?aaaeueiay A.E., Nooiiethaaa I.E., Aaeica?iaa I.A., Noaiaiaiei O.E., Aeieeineay I.A. ?ani?ino?aiaiiinoue e oa/aiea caaieaaaiee aioo?aiieo i?aaiia n?aaee ianaeaiey Eoaaineie iaeanoe iinea aaa?ee ia *a?iiaueueneie aoiiiie yeaeo?inoaioeee (*AYN).– Oai aea.– N. 311–316. 12. Aeieeineay I.A., Ieioieeia TH.I., Oia?oe A.N., O?ai/aiei N.I., Noaiaiaiei O.E Oaeoi?u ianoiie ianiaoeeoe/aneie ?acenoaioiinoe o?aoaia?iioeaeueiiai aea?aaa i?e iaeioi?uo oi?iao ianiaoeeoe/aneeo caaieaaaiee eaaeeo. // Iiaua aeinoeaeaiey a ?aiiae aeeaaiinoeea e oa?aiee ainiaeeoaeueiuo caaieaaaiee i?aaiia aeuoaiey / Oac. aeiee. ?ani. iao/ii-i?aeoe/. eiio.– Oa?ueeia, 1995.– N. 21. 13. Iooeioeaa A.E., Aeo?euae A.ss., O?ai/aiei N.I., Oia?oe A.N., Aeieeineay I.A.,?acoiiay O.A. E aii?ino i o?iiecaoeee caaieaaaiee i?aaiia aeuoaiey o /aeiaaea.– Oai aea.– N. 60–61. 14. Aeieeineay I.A., ?acoiiue ?.A. Ninoiyiea iee?ioee?eoeyoeee e ianiaoeeoe/aneay ?aaeoeaiinoue o?aoaia?iioeaeueiiai aea?aaa o aieueiuo o?iie/aneei iano?oeoeaiui a?iioeoii (OIA) // Iaaeeei-aiieiai/ii i?iaeaie i?iieneiaiai ?aaiiio / Ca. iaoeiaeo noaoae a/aieo EAeIO.– Eoaainuee, 1997.– N 103–106. 15. Ia/eoaeeiaa A.N., Aeieeineay I.A. Ninoiyiea eeaoi/iiai e aoii?aeueiiai eiioieoaoa o aieueiuo n caoyaeiui oa/aieai ino?ie iiaaiiiee // Oai aea.– N. 143–146. 16. Aeieeineay I.A., Ieioieeia TH.I. Oeeoieiae/aneia enneaaeiaaiea aeeiaieee ninoiyiey neecenoie o?aoaia?iioeaeueiiai aea?aaa (OAAe) i?e o?iie/aneii iano?oeoeaiii a?iioeoa // Iaoa?eaeu thaeeaeiie iao/ii-i?aeoe/aneie eiioa?aioeee, iina. 100-eaoeth iniia. 4-e ai?. a-oeu a. Eoaainea.– Eoaaine, 1995.– N. 9–10. 17. O?ai/aiei N.I. Oia?oe A.N. ?acoiiay O.A., Aeieeineay I.A. ?ieue yeieiae/aneeo oaeoi?ia a o?iiecaoeee ianiaoeeoe/aneeo caaieaaaiee eaaeeo.– Oai aea.– N. 35. 18. Aeieeineay I.A. INO-oano a ioeaiea ooieoeeiiaeueiiai ninoiyiey neecenoie iaiei/ee o?aoaia?iioeaeueiiai aea?aaa // THaieaeiee cai?iee oac iieiaeeo a/aieo oa niaoeiaeinoia EAeIO.– Eoaainuee, 1996.– N.47–48. 19. Niiei Ae.I., Ia?/aiei A.A., I?ae?aniia N.N., Aeieeineay I.A. ?ani?ino?aiaiiinoue o?iie/aneeo ianiaoeeoe/aneeo caaieaaaiee eaaeeo o aieueiuo eoaie/aneie aieaciueth na?aeoea // Cai?iee iaoeiaeo ?iaio V Anaoe?ainueei ia?aaee c ieoaiue iieieeiie/ii ni?aae.– Aeiii?iiao?ianuee, 1996.– N. 22. 20. Aeieeineay I.A. Ninoiyiea eeaoi/iuo oaeoi?ia ianoiie caueou o aieueiuo o?iie/aneei aiieii-iano?oeoeaiui a?iioeoii (OAIA) // Iaoa?iaee II c’caeo ooeciao?ia i ioeueiiiieiaia Oe?aie.– Eea, 1998.– C. 113. 21. Aeieeineay I.A., Aaoaineay E.TH. Aeoeaiinoue ianoiie nenoaiu aioeieneaeaioiie caueou (AIC) eaaeeo o aieueiuo o?iie/aneei iano?oeoeaiui a?iioeoii // Oai aea.– C. 113. 22. Aeieeinueea I.A Niin?a e?eoaaiiy caaino?aiiy o?ii?/iiai iano?oeoeaiiai a?iio?oo (OIA) c canoinoaaiiyi eaa?oeaoeio // ?a?no? iiaiaaaaeaiue Oe?a?ie.– 1998.– Aeione 8–9, ?a?no?aoe?eiee ?177/8/7. AIIOAOe?ss Aeieeinueea I.A. EE?I?EI-IAOIAAIAOE*IA OA?AEOA?ENOEEA ? E?EOAAIIss OAI?EO IA O?II?*IEE IANO?OEOEAIEE A?IIO?O C NOIOOIUeITH ?OAI?*IITH OAI?IAITH NA?Oess. – ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02.– aioo??oi? oai?iae.– Eoaainueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Eoaainuee, 1999. Aeine?aeaeaii iniaeeaino? iaoiaaiaco oa ia?aa?ao o?ii?/iiai iano?oeoeaiiai a?iio?oo (OIA) o oai?eo ia ?oai?/io oai?iao na?oey (?ON). O ianoaaeaieo oai?eo ee?i?/ia ea?oeia oa?aeoa?ecoaaeany ?icaeoeii neiae?iio aca?iiiai iaoyaeaiiy, ae?aci?oeie, i?ae o a?oi? ii??aiyiiy, ii?ooaiiyie ee?oeiiiai oa aoii?aeueiiai ?ioi?oaoo. Aeine?aeaeaiiy a?iioiaeueaaiey?ieo ciea?a oai?eo ia OIA aeyaeyei ci?ie ianiaoeeo?/ii? ?acenoaioiino? a?iio?a, ?ioaineai?o? ia oe? ?ON: aeaneaaiaoe?th ai?oae?th a?iio?a oa ?ae?oooaaiiy aeueaaiey?ieo iae?ioaa?a o ii?aeiaii? c? cieaeaiiyi aeeoo?caeaoiino? oa iaoaaie?/ii? aeoeaiino? cacia/aieo ee?oeiieo oei?a, iaio aeoeaiith i?a?aoe??th aei a?iioiaeueaaiey?iiai i?inoi?o iaeo?io?e?a oiui. Aiae?c ?ioaa?aeueieo iieaciee?a i?noeaai? nenoaie aioeieneaeaioiiai caoenoo, ui aoa i?iaaaeaiee c aeei?enoaiiyi iiey?ia?ao?/iiai iaoiaeo aeine?aeaeaiiy a?iioiaeueaaiey?ieo ciea?a, cana?ae/ea ii??aiyii ae?aci?oee aeenaaeain o a?e ia?aeeniiai ieenethaaiiy e?i?ae?a. Ia i?aea?oio? niinoa?aaeaiiy oa?aiaaoe/ieo aoaeo?a eaa?oeaoeio oa aaieoeeo ?ic?iaeaii canaaee aei i?ecia/aiiy oeeo i?aia?ao?a a eiiieaeniiio e?eoaaii? OIA o noeoiiino? c ?ON. Eeth/ia? neiaa: o?ii?/iee iano?oeoeaiee a?iio?o (OIA), ?oai?/ia oai?iaa na?oey (?ON), eaa?oeaoei, aaieoee, ianiaoeeo?/ia ?acenoaioi?noue a?iio?a. AIIIOAOeEss Aeieeineay I.A. EEEIEEI-IAOIAAIAOE*ANEAss OA?AEOA?ENOEEA E EA*AIEA AIEUeIUO O?IIE*ANEEI IANO?OEOEAIUI A?IIOEOII N NIIOONOAOTHUAE EOAIE*ANEIE AIEACIUeTH NA?AeOeA. – ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02.– aioo?aiiea aieacie.– Eoaaineee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Eoaaine, 1999. Enneaaeiaaiu iniaaiiinoe iaoiaaiaca e oa/aiey o?iie/aneiai iano?oeoeaiiai a?iioeoa (OIA) o aieueiuo eoaie/aneie aieaciueth na?aeoea (EAN). Eeeie/aneay ea?oeia caaieaaaiey oa?aeoa?eciaaeanue au?aaeaiiui neiae?iiii acaeiiiai ioyaiuaiey. *anoioa auyaeaiey iniiaiuo neiioiiia OIA o aieueiuo EAN auea noiaeiie n oaeiaie o aieueiuo OIA aac niioonoaothueo caaieaaaiee na?aea/ii-ninoaeenoie nenoaiu (a?oiia n?aaiaiey), iaeiaei, i?e ni/aoaiiie iaoieiaee ioia/aeanue aieueoay oyaeanoue auyaeaiiuo neiae?iiia a ni/aoaiee n iaiaa au?aaeaiiie eeoi?aaei/iie ?aaeoeeae, iaiaa cia/eoaeueiuie eciaiaieyie a aaiia?aiia, ino?ioaciauie ?aaeoeeyie. Aeoeaiinoue ainiaeeoaeueiiai i?ioeanna o yoeo aieueiuo auea oaeaea ianeieueei ieaea, /ai a a?oiia n?aaiaiey. A ioee/ea io aieueiuo a?oiiu n?aaiaiey, o eioi?uo iaaethaeaeanue eeiaeiay caaeneiinoue oyaeanoe aaioeeyoeeiiiuo ia?ooaiee io aeoeaiinoe ainiaeaiey, o aieueiuo OIA a ni/aoaiee n EAN aieaa au?aaeaiiua yaeaiey aeuoaoaeueiie iaaeinoaoi/iinoe nii?iaiaeaeaeenue iaiueoae aeoeaiinoueth ainiaeeoaeueiiai i?ioeanna. A aeaiiie a?oiia aieueiuo /aua auyaeyeenue i?eciaee yioecaiu eaaeeo, iiaaiioea?ica e aoi?e/iie eaai/iie aeia?oaicee. A ia?eiae iaino?aiey OIA ioia/aeinue ooyaeaeaiea oa/aiey EAN, caeeth/aaoaany a o/auaiee i?enooiia noaiiea?aeee eee aeaathoa caaieaaaiey, onoaoaeaiee aeiiene/aneeo eciaiaiee ieiea?aea, ooyaeaeaiee ia?ooaiee ?eoia na?aeoea. A i?ioeanna ea/aiey iieiaeeoaeueiay aeeiaieea o aieueiuo n niioonoaothuae EAN iineea iaiaa au?aaeaiiue oa?aeoa?, /ai a a?oiia n?aaiaiey: o aieueoaai /enea aieueiuo i?e auienea ec noaoeeiia?a nio?aiyeny eaoaeue, ia aue eoie?iaai ainiaeeoaeueiue i?ioeann a a?iioao, nio?aiyeenue i?iyaeaiey anoaii-aaaaoaoeaiiai neiae?iia. O ianeaaeiaaiiuo aieueiuo auyaeaiu aieaa cia/eoaeueiua, /ai a a?oiia n?aaiaiey, ia?ooaiey eeaoi/iiai e aoii?aeueiiai caaiueaa eiioieoaoa a aeaea aoi?e/iiai eiioiiaeaoeoeeoiiai ninoiyiey noi?anni?iiai oeia, noieeiai iiauoaiey niaea?aeaiey oee?eoee?othueo eiioiiuo eiiieaenia a nuai?ioea e?iae. Enneaaeiaaiey a?iioiaeueaaiey?iuo niuaia (AAN) aieueiuo OIA a ni/aoaiee n EAN iaia?oaeeei oneeaiioth ii n?aaiaieth n aieueiuie OIA, ia no?aaeaaoeie na?aea/ii-ninoaeenouie caaieaaaieyie, aeaneaaiaoeeth yieoaeey a?iioia, ?ae?ooe?iaaiea aeueaaiey?iuo iae?ioaaia (AI), ni/aoaaoaany n iaiaa aeoeaiie iea?aoeeae a a?iioiaeueaaiey?iia i?ino?ainoai iaeo?ioeeia. Enneaaeiaaiea ooieoeeiiaeueiiai ninoiyiey yieoaeeioeeoia e AI iaia?oaeeaaei nieaeaiea aeecianiiniaiinoe e iaoaaiee/aneie aeoeaiinoe oeacaiiuo eeaoi/iuo oeiia. Aiaeec ninoiyiey aaeaina “ia?aeeniia ieeneaiea eeieaeia–aioeieneaeaioiay caueoa” (“IIE–AIC”), i?iaiaeeaoeeny n iiiiuueth iiey?ia?aoe/aneiai enneaaeiaaiey AAN auyaee o yoeo aieueiuo aieaa au?aaeaiiue, /ai a a?oiia n?aaiaiey naeaea a noi?iio iineaaeiaai. Oa?aeoa?ii oaeaea, /oi i?e ni/aoaiiie iaoieiaee aeeiaieea eco/aiiuo ia?aiao?ia a i?ioeanna ea/aiey auea ieieiaeueiie, oiaaea eae a a?oiia n?aaiaiey iaaethaeaeinue /anoe/iia ainnoaiiaeaiea auyaeaiiuo ia?ooaiee a i?ioeanna ea/aiey. Eco/aia yooaeoeaiinoue aaieoeea e eaa?oeaoeia a eiiieaeniii ea/aiee aieueiuo OIA a ni/aoaiee n EAN. N?aaiaiea oa?aiaaoe/aneeo yooaeoia aaieoeea e eaa?oeaoeia auyaeei, /oi i?e niiinoaaeiuo eeeie/aneeo yooaeoao i?aia?aoia a ioiioaiee oa/aiey OIA, au?aaeaaoeony a iniiaiii a oiaiueoaiee oyaeanoe iano?oeoeaiiai neiae?iia e aeinoeaeaiee aieaa aeeeoaeueiie ?aiennee, i?eiaiaiea eaa?oeaoeia i?eaaei oaeaea e aieaa aeaaii?eyoiiio oa/aieth EAN – o?aaeaieth i?enooiia noaiiea?aeee, oeo/oaieth iaoaaieecia ieiea?aea ii aeaiiui YEA, iiauoaieth oiea?aioiinoe e oece/aneie iaa?ocea, /oi aeaeaao i?eiaiaiea eaa?oeaoeia i?aaeii/oeoaeueiui i?e ea/aiee OIA a ni/aoaiee n EAN. A ioiioaiee aeaenoaey ia nenoaio ianoiie caueou a?iioia neaaeoao ioiaoeoue i?aiaeaaeaiea o aaieoeea noeioee?othuaai aeeyiey ia iaoaaieeci eeaoie a?iioeaeueiiai yieoaeey, i?iyaeaoaainy a iiauoaiee aeecianiiniaiinoe yieoaeeioeeoia e oiaiueoaiee eioaineaiinoe aeaneaaiaoeaiuo i?ioeannia, a oaeaea au?aaeaiiiai aioeieneaeaioiiai yooaeoa. Iineaaeiee i?iyaeeny a oiaiueoaiee niaea?aeaiey a AAN anao iniiaiuo eeannia AOE, /oi, aiciiaeii, noaei i?iyaeaieai ni/aoaiey i?yiiai e iai?yiiai aioeieneaeaioiiai yooaeoia i?aia?aoa. O eaa?oeaoeia aeiieie?iaaei iieiaeeoaeueiia aicaeaenoaea ia aeecianiiniaiinoue e eenei?iaeiue iaoaaieeci AI; auei oaeaea au?aaeaii oiaiueoaiea iiae aeeyieai i?aia?aoa iea?aoeee a a?iioiaeueaaiey?iia i?ino?ainoai iaeo?ioeeia, /oi, aa?iyoii, io?aaeaao i?ioeainiaeeoaeueiue yooaeo. A n?aaiaiee n aaieoeeii, ei??eae?othuee yooaeo eaa?oeaoeia aue ianeieueei iaiaa au?aaeai a ioiioaiee yieoaeeioeeoia, iaeiaei aeinoeaaeanue aieaa au?aaeaiiay aeoeaaoeey eenei?iaecaaeneiuo iaoaieciia eeeeeiaa AI. Aioeieneaeaioiia aeaenoaea i?aia?aoa i?iyaeyeinue i?aeiouanoaaiii a o?ainoi?iaoeee iaeaieaa oiene/iuo aeae?ieneeueiuo ?aaeeeaeia e aeoeae?iaaiiiai eenei?iaea a iaiaa aeoeaiua ia?aeeniua niaaeeiaiey, /oi iicaieyao i?aaeiieiaeeoue i?aiaeaaeaiea o i?aia?aoa i?yiie aioeieneaeaioiie aeoeaiinoe. Oeacaiiay iniaaiiinoue aeaeaea oa?iaeiaeeiaieeo i?aia?aoa a yoii iai?aaeaiee ianeieueei iaiaa yooaeoeaiie, /ai o aaieoeea. ?ac?aaioaiu iieacaiey e iacia/aieth eaa?oeaoeia e aaieoeea a eiiieaeniii ea/aiee OIA a ni/aoaiee n EAN, i?aaeeiaeaiiua iaoiaeu ea/aiey aiaae?aiu a i?aeoeeo ea/aaiuo o/?aaeaeaiee. Eeth/aaua neiaa: o?iie/aneee iano?oeoeaiue a?iioeo (OIA), eoaie/aneay aieaciue na?aeoea (EAN), eaa?oeaoei, aaieoee, ianiaoeeoe/aneay ?acenoaioiinoue a?iioia. RESUME Dolinskaya M.G. CLINICAL, PATHOGENETICAL CHARACTERISTICS AND TREATMENT OF PATIENTS WITH CHRONIQUE OBSTRUCTIVE BRONCHITIS IN CONJUNCTION WITH CORONARY HEART DISEASE. – Manuscript. Thesis for a candidate's degree by speciality 14.01.02.– internal diseases. –Lugansk State Medical University, Lugansk, 1999. The dissertation is devoted to particularities of chronic obstructive bronchitis (COB) pathogenesis and course in patients with coronary heart disease (CHD) investigation. The clinical picture was characterised by mutual severity syndrome. More evident cellular and humoral immunity disorders in comparison with those in COB patients without accompanied pathology occurred. The alteration of bronchial non-specific defence had been resulted in more intensive bronchial epithelium casting and alveolar macrophages recruitment, as well as decreased viability and metabolic activity of those cell types coupled with less active neutrophils migration into bronchoalveolar lumen. The analysis of integral parameters for local antioxidant defence system using the bronchoalveolar lavage fluid voltammetry had showed comparatively significant balance shifting towards lipid peroxidation. The base for antioxidant drugs bemitil and quercetin application in comprehensive treatment of patients with combined COB and CHD was worked out. The effectivness of these drugs had been proved. Key words: chronic obstructive bronchitis (COB), coronary heart disease (CHD), quercetin, bemitil, bronchial non-specific defence.

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