Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i. I. I. Aiaiiieueoey.

Ai??oia ?aaiia Ethaiie??aia

OAeE: 616. 981. 49 — 097 — 053. 2 — 085. 246. 2 : 546. 26

Ee?i?ei-eaai?aoi?i? c?ooaiiy o oai?eo ia naeueiiiaeueic ae?oae oa ?o
ei?aeoe?y aioa?ini?aaioii ”Neeea?ae I”.

14. 01. 10- iaae?ao??y.

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a-1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia o oa?iii?euenuee?e aea?aeaai?e iaaee/i?e aeaaeai??
?i.?.ss.Ai?aa/aanueeiai, IIC Oe?a?ie

Iaoeiaee ea??aiee: /eai-ei?aniiiaeaio AII Oe?a?ie, aeieoi? iaaee/ieo
iaoe, i?ioani? Ni?yi ?aai Naiaiiae/, Oa?iii?euenueea iaaee/ia aeaaeai?y
?i. ?.ss.Ai?aa/aanueeiai, caa.eao. aeeoy/eo oai?ia iaaee/iiai
oaeoeueoaoo

Ia?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, i?ioani? E?aia??a Na?a?e
Ieaenaiae?iae/ Ee?anueeee iaoe?iiaeueiee iaaee/iee oi?aa?neoao
?i.I.I.Aiaiiieueoey, caa.eao. aeeoy/eo ?ioaeoe?eieo oai?ia.

aeieoi? iaaee/ieo iaoe, i?ioani? *a?ieoiaa Ethaeieea ?aai?aia, Ee?anueea
iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea. caa.eao.
aeeoy/eo ?ioaeoe?eieo oai?ia.

I?ia?aeia onoaiiaa: Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo ioi?iie
caei?iay ae?oae oa i?aee?oe?a, IIC Oe?a?ie, i.Oa?e?a

Caoeno aeena?oaoe?? a?aeaoaeaoueny 21.01.99 i 13:30 ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.003.02 Iaoe?iiaeueiiai iaaee/iiai
oi?aa?neoaoo ?i.I.I.Aiaiiieueoey ca aae?anith 252004, i. Ee?a-4,
aoeueaa? Oaa/aiea, 17.

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? Iaoe?iiaeueiiai
iaaee/iiai oi?aa?neoaoo ?i.I.I.Aiaiiieueoey ca aae?anith 252004, i.
Ee?a, aoe.Ciieia?/ia,3, noiiaoieia?/iee ei?ion.

Aaoi?aoa?ao ?ic?neaii 18.12.98 ?ieo.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee ,

aeieoi? iaaee/ieo iaoe N.A.Nae?eae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie. Aino?? eeoeia? ?ioaeoe?? o ae?oae aoee ?
caeeoathoueny iaei??th ?c iaeaaaeeea?oeo i?iaeai na?aae ?ioeo
?ioaeoe?eieo caoai?thaaiue. I?ioyaii inoaii?o aeanyoee?oue a Oe?a?i?, ye
? o anueiio na?o?, o ii??aiyii? c ?ioeie eeoeiaeie ?ioaeoe?yie, cia/ii
c?inea caoai?thaai?noue ia naeueiiiaeueic. Ia nueiaiaei? naeueiiiaeueic
— iae/ano?oa i?e/eia aaeoa??eieo aioa?ieie?o?a o ae?oae. 80% oai?eo —
ae?oe ?aiiueiai a?eo. O ieo caoai?thaaiiy ia?aa?aa? oyae/a, /ano?oa
aeieeathoue oneeaaeiaiiy, eaoaeuei? iane?aeee, iniaeeai o iaiiaeyo c
ia?aiaoyaeaiei i?aii?a?aeiei oiiii (N.I.E?aia?aa, 1995; I.E.Ienaae/,
1995; H.R.Stutman, 1994).

Ii?yae ?c c?inoaiiyi oa?/iaiai oeyoo ia?aaea/? naeueiiiae, i?ioyaii
inoaii?o ?ie?a ii/ano?oaea ?a?no?aoe?y aini?oaeueieo niaeao?a
naeueiiiaeueico. ?o aieiaia i?e/eia — oe?iea ?iciianthaeaeaiiy
aioea?ioeei?acenoaioieo naeueiiiae, a ia?oo /a?ao S.typhimurium.
Aioo??e?ea?iyi? niaeaoe iae/ano?oa ?a?no?othoueny o aeeoy/eo
a?aeae?eaiiyo, iieiaiaeo aoaeeieao, iathoue a?oiiaee oa?aeoa?.
Aeaea?aeii ?ioaeoe?? ? oai?? ae?oe, aaoueee, iaaee/iee ia?niiae. Oeyo
iioe?aiiy — eiioaeoii-iiaooiaee. Naeueiiiaeueicia ?ioaeoe?y
iaoa?iao?oueny ia ?io? caoai?thaaiiy, ia? oyae/ee ia?aa?a, /ano?o?
iani?eyoeea? iane?aeee (E.I.Ieethoeia e niaao., 1997; A.?.Iinothe, 1998;
H. Vahaboglu, 1996).

Aioeaaeoa??aeueia oa?ai?y ?c canoinoaaiiyi aioea?ioee?a o e?eoaaii?
aioo??e?ea?iyiiai naeueiiiaeueico /anoi iaaoaeoeaia, ni?ey? ?icaeoeo
aeenaaeoa??ico, i?eai?/aiith ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio. Oea,
a naith /a?ao, coiiaeth? caoyaeiee ia?aa?a caoai?thaaiiy, o?eaaea
aaeoa??iaeae?eaiiy (I.?.No?aeeiaa e niaao., 1993; A.O.O/aeeei e niaao.,
1996; H.Szajewska, P.Albrecht, 1997).

A?oaee eaneaae iaoieia?/ieo ci?i a i?aai?ci? ae?oae, oai?eo ia
naeueiiiaeueic, iaaoaeoeai?noue aioea?ioeeioa?ai?? coiiaeththoue
iaiao?aei?noue aeei?enoaiiy iiaeo iaoiaaiaoe/ieo cania?a o ?o e?eoaaii?,
ye? iai?aaeai? ia iaeo?ae?caoe?th oa aeaaaeaiiy oienei?a. Iaeiei ?c oeeo
cania?a ? aioa?ini?aaioe.

I?ae /an aioa?ini?aoe?? iiaeeiathoueny ? aeaiaeyoueny c i?aai?cio
?a/iaeie, ye? iio?aieee o oeoieiai-eeoeiaee o?aeo cciai?, aeeooiaeothoue
o eeoe?aiee c e?ia?, aeae?eythoueny o i?ina?o eeoe?aieea ?c o?aaieie
nieaie, ooai?ththoueny o o?aaiiio eaiae? (I.A.Aiae?ae/ei, I.N.Aiaothe,
1992).

Inoaii?ie ?ieaie c??n ?ioa?an aeine?aeiee?a aei aenieiaeenia?nieo
e?aiiacai?a, ni?aoe?ei? yeino? yeeo cia/ii aeu?, o ii??aiyii? c
aioa?ini?aaioaie ?ioeo a?oi. Iiceoeaiee aoaeo iie?ni?ao o e?eoaaii?
eeoeiaeo oieneeic?a o ae?oae, ui i?iyaeany oaeaeeei eoioaaiiyi
ee?i?/ieo, eaai?aoi?ieo iciae ?ioieneeaoe??, iie?auaii? ?ioiiiiai
noaoono io?eiaee ?.A.Aaeaeoe (1991); A.?.Iinothe ? ni?aaao. (1991);
E.A.Ieia (1994).

Iacaaaeath/e ia oni?oe canoinoaaiiy aioa?ini?aaio?a o e?eoaaii? aino?eo
eeoeiaeo ?ioaeoe?e o ae?oae, ?yae i?iaeai iio?aao? ae??oaiiy. Ia
ciaeaeaii ?ia?o, i?enay/aieo canoinoaaiith “Neeea?aeo I” o e?eoaaii?
oai?eo ia naeueiiiaeueic ae?oae, eiai aieea ia ee?i?/iee ia?aa?a,
iieacieee aiaeiaaiii? ?ioieneeaoe??, ?ioiieia?/io ?aaeoeai?noue,
i?e?iaiee iaecaae eeoe?aieea caeaaeii a?ae oyaeeino? ia?aa?ao
caoai?thaaiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, oaiaie, ieaiaie

Aeena?oaoe?eia ?iaioa ? o?aaiaioii eiiieaenii? ieaiiai? iaoeiai? ?iaioe
eaoaae?e aeeoy/eo oai?ia Oa?iii?euenueei? aea?aeaaii? iaaee/ii?
aeaaeai?? ?i. ?.ss.Ai?aa/aanueeiai ca oaiith: “Aiaeiaaiia ?ioieneeaoe?y
o ae?oae c ??ciith iaoieia??th oa ?? aieea ia iaoiaaiaoe/i? iaoai?cie ?
ee?i?/i? i?iyae caoai?thaaiue”, ui aeeiioaaeanue o 1992-1997 ??. ca
ieaiii IIC Oe?a?ie, ? aea?ae?a?no?aoe?? 096V023277, oeo? 5E-98.

Iai?yiie aeine?aeaeaiiy ocaiaeaeaii c oi?aae?iiyi ioi?iie caei?ia’y
Oa?iii?euenueei? iaeanii? aea?aeaaii? aaei?i?no?aoe??.

Iaoa aeine?aeaeaiiy: c’ynoaaoe ?ieue ee?i?ei-iaoaaie?/ieo ii?ooaiue o
oyaeeino? ia?aa?ao naeueiiiaeueico o ae?oae, iaoiaaiaoe/ii iaa?oiooaaoe
iaiao?aei?noue canoinoaaiiy aioa?ini?aoe?? “Neeea?aeii I” a eiiieaeni?e
oa?ai?? oe??? iaaeoae.

Caaea/? aeine?aeaeaiiy:

1. Aeyaeoe ee?i?/i? oa eaai?aoi?i? i?iyae aiaeioieneeico o ae?oae,
oai?eo ia naeueiiiaeueic.

2. Aea/eoe iniaeeaino? ?ioiiiai caoenoo oa noai i?e?iaiiai iaecaaeo
eeoe?aieea o aeine?aeaeoaaiiai eiioeiaaioa ia oe? aiaeioienai??.

3. Iaoiaaiaoe/ii iaa?oiooaaoe aeioe?euei?noue aeeth/aiiy aei eiiieaeno
e?eoaaiiy oai?eo ae?oae aioa?ini?aaioa c iaoith e?ea?aeaoe??
aiaeioienai?? oa a?aeiiaeaiiy aiiainoaco.

4. Ioe?ieoe aoaeoeai?noue aeei?enoaiiy aioa?ini?aaioo “Neeea?ae I” o
eiiieaen? oa?ai?? ae?oae, oai?eo ia naeueiiiaeueic, caeaaeii a?ae
nooiaiy oyaeeino? ia?aa?ao caoai?thaaiiy.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. A ?acoeueoao? ee?i?/ieo oa
eaai?aoi?ieo aeine?aeaeaiue o ae?oae, oai?eo ia naeueiiiaeueic, ia
i?aenoaa? aeinoia??iiai ca?eueoaiiy INI o e?ia?, c?inoaiiy iieaciee?a
A??, E?? aeyaeaii cia/i? ci?ie aiiainoaco o aeaeyae? NA?, io?eiaii aeai?
i?i ?ieue aiaeioienai?? o no/anieo ai?aeai?ieia?/ieo oiiaao o
i?aeo?eiaii? iaoieia?/iiai i?ioeano, coiiaeaiiai naeueiiiaeaie oa ?o
oieneiaie, a i?aai?ci?, ui noi?iaiaeaeo?oueny ae?aaeaieie a?aeoeeaiiyie
c aieo ee?oeiii? eaiee ?ioi?oaoo oa o i?e?iaiiio iaecaae? eeoe?aieea. C
iaoith e?ea?aeaoe?? c?ooaiue aiiainoaco aia?oa iaoiaaiaoe/ii
iaa?oioiaaia, ?ic?iaeaia ? ai?iaiaaia o ee?i?oe? aeeoa?aioe?eiaaia
oa?ai?y naeueiiiaeueico o ae?oae ?c canoinoaaiiyi aioa?ini?aaioo
“Neeea?ae I”, caeaaeii a?ae nooiaiy aiaeioieneeico.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a. Anoaiiaeaii, ui ?icaeoie
aiaeioieneeico ? aaaeeeaith eaieith o ia?aa?ao naeueiiiaeueico o ae?oae.
Ia oe? aiaeioienai?? a?aei?/aii i?eai?/aiiy ee?oeiii? eaiee ?ioi?oaoo,
ii?ooaiiy i?e?ia?ioeaiico eeoe?aieea. Ee?i?/ii ai?iaiaaii ?
cai?iiiiiaaii ei?eaoaaoe aeyaeai? a i?aai?ci? oai?i? aeeoeie c?ooaiiy
aiiainoaco aeeoa?aioe?eiaaii, caeaaeii a?ae nooiaiy aiaeioieneeico, ui
iiceoeaii aieeaaei ia ia?aa?a oa aene?ae caoai?thaaiiy. ?ic?iaeaii ?
ai?iaiaaii aeice ? ?aaeei aaaaeaiiy e?aii?ei?aai?/iiai aioa?ini?aaioa
“Neeea?ae I” c iaoith eiiieaeniiai e?eoaaiiy oai?eo ia naeueiiiaeueic
ae?oae.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii iniaenoi i?iaaaeaii ee?i?/ia
niinoa?aaeaiiy oa e?eoaaiiy 84 ae?oae, oai?eo ia naeueiiiaeueic oa
i?iaiae?ciaii aeieoiaioaoe?th 51 iaoe??ioa, ui ia?aaoaaee ia
noaoe?iia?iiio e?eoaaii? o ?ioaeoe?eiiio a?aeae?eaii? Oa?iii?euenueei?
i?nueei? aeeoy/i? ee?i?/ii? e?ea?i? oa ?ioaeoe?eii-aieniaaiiio
a?aeae?eaii? Oa?iii?euenueei? iaeanii? aeeoy/i? ee?i?/ii? e?ea?i?.
I?iaaaeaii aiae?c io?eiaieo ?acoeueoao?a, ?o iaoaiaoe/ia ia?iaea,
noi?ioeueiaai? iniiai? aeniiaee. Aeinoia??i?noue io?eiaieo aeaieo
i?aeoaa?aeaeaii ia?aeiiith aeieoiaioaoe??th ia aoai? iiia?aaeiuei?
aenia?oece ?iaioe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy ? ?acoeueoaoe
aeine?aeaeaiue iaaiai?ai? ia iaoeiaiio can?aeaii? eaoaae? aeeoy/eo
oai?ia iaaee/iiai oaeoeueoaoo, oaeoeueoaoo i?neyaeeieiiii? i?aeaioiaee
e?ea??a, ?ioaeoe?eieo oai?ia Oa?iii?euenueei? aea?aeaaii? iaaee/ii?
aeaaeai?? ?i. ?.ss.Ai?aa/aanueeiai (1998 ?.). Iaoa??aee aeena?oaoe??
iia?aeiieai? oa iaaiai?ai? ia iaoeiai-i?aeoe/i?e eiioa?aioe?? aei
100-??//y canioaaiiy EIAe?A?O ?i. E.A.A?iiaoaanueeiai (Ee?a, 1996),
i?aenoieia?e iaoeia?e eiioa?aioe?? nooaeaio?a ? iieiaeeo a/aieo
iaaee/iiai ?inoeoooo (Oa?iii?eue, 1996), i?aenoieia?e iaoeia?e
eiioa?aioe?? “Caeiaooee ee?i?/ii? oa aenia?eiaioaeueii? iaaeeoeeie”
(Oa?iii?eue, 1997 ?.), ? oa ?? i?aeia?iaeieo iaaee/ieo eiia?anao
nooaeaio?a ? iieiaeeo a/aieo (Oa?iii?eue, 1997-1998 ??.), V c’?cae?
?ioaeoe?ii?no?a Oe?a?ie (Oa?iii?eue, 1998), ia ee?i?/ieo eiioa?aioe?yo
e?ea??a-iaae?ao??a iaeanii? aeeoy/i? ee?i?/ii? e?ea?i? i.Oa?iii?eue
(1996-1998 ??.).

Ioae?eaoe?? ca oaiith aeena?oaoe??. ?acoeueoaoe aeena?oaoe?eii? ?iaioe
iioae?eiaai? o 3 noaooyo o oaoiaeo aeaeaiiyo, ?aeiiaiaeiaaieo AAE
Oe?a?ie, 8 iaoeiaeo i?aoeue aeaeaii o iaoa??aeao iaoeiaeo eiioa?aioe?e,
eiia?an?a, c’?caeo.

Ianya oa no?oeoo?a aeena?oaoe??. Iiaiee ianya ?iaioe 175 noi??iie
iaoeiiieniiai oaenoo, c ieo oaaeeoe?, ?enoiee, nienie aeei?enoaii?
e?oa?aoo?e caeiathoue 61 noi??ieo. Aeena?oaoe?y neeaaea?oueny ?c anooio,
iaeyaeo e?oa?aoo?e, /ioe?ueio ?icae?e?a aeanieo aeine?aeaeaiue,
i?neyiiae, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e, nienea aeei?enoaii?
e?oa?aoo?e. ?iaioa ?ethno?iaaia 15 oaaeeoeyie oa 14 ?enoieaie.
A?ae?ia?ao?/iee iieaae/ee aeeth/a? 307 aeaea?ae.

CI?NO ?IAIOE

Ia’?eo oa iaoiaee aeine?aeaeaiiy. Iniiao ?iaioe noaiiaeee ee?i?/i?
niinoa?aaeaiiy ca 135 ae?oueie, oai?eie ia naeueiiiaeueic, c ieo: 93 —
aei ?ieo oa 42 — noa?oa 1 ?ieo. Eiio?ieueio a?oio neeaee 21 oa 23
i?aeoe/ii caei?iaeo aeeoeie, a?aeiia?aeiiai a?eo. Na?aae caaaeueii?
e?eueeino? oai?eo ia?aaaaeaee oeii/eee — 57,78%. Ianoaaeaiiy
i?iaiaeeeinue ia aac? ?ioaeoe?eiiai a?aeae?eaiiy Oa?iii?euenueei?
i?nueei? aeeoy/i? ee?i?/ii? e?ea?i? oa ?ioaeoe?eii-ae?aaiinoe/iiai
a?aeae?eaiiy Oa?iii?euenueei? iaeanii? aeeoy/i? ee?i?/ii? e?ea?i?.

Aeey ee?i?/ii? oa?aeoa?enoeee ianoaaeoaaieo oai?eo aeei?enoiaoaaee
ee?i?/io eeaneo?eaoe?th naeueiiiaeueic?a, ?ic?iaeaio c a?aooaaiiyi
ee?i?ei-iaoiaaiaoe/ieo i?eioeei?a. Ee?i?/io ioe?ieo oyaeeino? ia?aa?ao
aano?i?ioanoeiaeueii? oi?ie naeueiiiaeueico i?iaiaeeee ca?aeii
e?eoa???a, iiaeaieo I.E.Ienaae/, A.O.O/aeeeiui (1990).

Ae?aaiic aano?i?ioano?iaeueii? oi?ie naeueiiiaeueico anoaiiaethaaee ia
iniia? oa?aeoa?ieo ee?i?/ieo iciae, ai?aeai?ieia?/ieo aeaieo ?
iiceoeaieo ?acoeueoao?a aaeoa??ieia?/ieo aeine?aeaeaiue. Aaeoa??ieia?/ii
aeine?aeaeoaaee aeii?iaeiaiiy oai?eo, na/o, e?ia.

Aeey ioe?iee oyaeeino? ia?aa?ao caoai?thaaiiy aeei?enoiaoaaee ee?i?/i?
e?eoa???: ae?aaeai?noue oaiia?aoo?ii? ?aaeoe??, neiioii?a o?aaeaiiy
i?aai?a o?aaeaiiy, na?oeaai-noaeeiii?, na/iaeae?eueii? nenoai, ii?ooaiue
aiaeii-nieueiaiai iai?io; ea?oeio ia?eoa??eii? e?ia?, a oaeiae ??aaiue
INI o ne?iaaooe? e?ia? ye ia?ea??a aiaeiaaiii? ?ioieneeaoe?? i?e
aeiaaeei? oaee? 280 oa 254 ii, aaee/eio A??, E??.

Aeine?aeaeaiiy ?icii/eiaee c aeaoaeueiiai cai?o nea?a, aiaiiaco
caoai?thaaiiy oa aeeooy, ai?aeai?ieia?/iiai aiaiiaco. Caa?oaee oaaao ia
oa?aeoa? ? ae?aaeai?noue ia?oeo neiioii?a oai?iae, /an i?e?aeiaiiy
aeeniaine/ieo ?iceaae?a, ?o o?eaae?noue. I?e cai?? ai?aeaiaiiaco
anoaiiaethaaee, aea a?aeaoeiny ?io?eoaaiiy (o noaoe?iia??, aaeiia) oa
oeyo ia?aaea/? caoaeieea (oa?/iaee, eiioaeoii-iiaooiaee). Caa?oaee oaaao
ia iayai?noue iaoyaeaiiai i?aii?a?aeiiai oiio: iaoieia?/iee ia?aa?a
aaa?oiino? oa iieia?a aeaiith aeeoeiith, ?aii? ooo/ia ia?aoe?iiaeueia
aeaiaeiaoaaiiy, ?ao?o, aiai?y, a?iio?io?y, aiiiae?? eiinoeoooe??,
ia?aianai? ?ai?oa caoai?thaaiiy (a?ae ia?iaeaeaiiy ? aei iinooieaiiy a
noaoe?iia?) oa canoinoaaiiy aioea?ioee?a aeey ?o e?eoaaiiy.

Eiiieaenia ioe?iea ioiiethaaea oa?aeoa? oa ae?aaeai?noue aeeniaine/ieo
i?iya?a, neiae?iio ?ioieneeaoe??, ii?ooaiiy aiaeii-aeaeo?ie?oiiai
iai?io, ci?i c aieo i?aai?a aeeoaeueii?, na?oeaai-noaeeiii?,
na/iaeae?eueii?, ia?aiai? nenoai, iayai?noue aaiaoi-e??iaeueiiai
neiae?iio.

Ae?oyi i?iaiaeeany caaaeueiii?eeiyoee eiiieaen eaai?aoi?iiai
ianoaaeaiiy. O caaaeueiiio aiae?c? e?ia? caa?oaee oaaao ia ??aaiue
aiai??, ae?aaeai?noue caiaeueieo ci?i (eaeeioeeoico, cnoao
eaeeioeeoa?ii? oi?ioee ae?ai, oiene/ii? ca?ienoino? iaeo?io?e?a,
i?enei?aiiy OIA). O caaaeueiiio aiae?c? na/? — ia iciaee oiene/iiai
o?aaeaiiy ie?ie. O eii?ia?ai? — ia noai oa?iaioaoeaii? ooieoe?? oiiei?
eeoee oa caiaeuei? ci?ie neeciai? iaieiiee oianoi? eeoee.

E??i oiai, i?iaiaeeeinue aea/aiiy e?euee?niiai oa ye?niiai noaio
i?e?ioei?e oianoi? eeoee ca iaoiaeii ?.A.Aiooaei-E?oaae oa
O.E.A?eueoainueei? (1969). ?acoeueoaoe aeine?aeaeaiiy i?e?ioei?e oaeae?e
ioe?ithaaee ca e?eoa??yie ?.I.Aeio?ii? (1981).

Aecia/aiiy O- (A-?OE), A- (AAN-?OE), I-e?ioioeeo?a, i?iaiaeeee ca
N.Mendes (1973) o iiaeeo?eaoe?? O.?.A??oeia ? ni?aaao. (1984).

Noaiiioeyoe?? O-e?ioioeeo?a aecia/aeeny ca aeiiiiiaith oanoo /ooeeaino?
aei oaio?e?io ca iaoiaeii A.Shore et al. (1978).

Aeoeai?noue aoii?aeueiiai ?ioi?oaoo aea/aee ca ai?noii iniiaieo eean?a
?ioiiaeiaoe?i?a G, A, M, iaoiaeii ?aae?aeueii? ?ioiiaeeooc?? o aae? ca
G.Mancini ? ni?aaao. (1965).

??aaiue INI aecia/aee ca?aeii iaoiaeeee I.?.Aaa??aeyia ? ni?aaao. (1984,
1985). I?e aeiaaeei? oaee? 280 ii aecia/aee iieaeoee na?aaeiuei? iane
(INI1), ui i?noyoue a?iiaoe/i? ai?iieeneioe, a i?e aeiaaeei? oaee? 254
ii — (INI2), ioeeaioeaee.

A?eo?ioeeoa?iee ?iaeaen aiaeiaaiii? ?ioieneeaoe?? (A??) aecia/aee ca
iaoiaeii A.A.Oiaaeaa?aa oa ni?aaao. (1988).

Aeey ioe?iee nooiaiy ae?aaeaiino? ?ioieneeaoe?? ae?aoiaoaaee
eaeeioeeoa?iee ?iaeaen (E??) ca iaoiaeeeith E.ss.Eaeueo-Eae?oa o
iiaeeo?eaoe?? A.E.Ino?ianueeiai (1950).

Io?eiai? ?acoeueoaoe ii?aoeueiaai? iaoiaeii aa??aoe?eii? noaoenoeee
ca?aeii ?aeiiaiaeaoe?e A.TH.O?aaoa (1975), A.E.Eociaoeiaa (1978).

Noaoenoe/ia ia?iaea aeaieo i?iaiaeeeanue ia i?ia?aiiaaiiio
i?e?ieaeueeoeyoi?? “Aeaeo?ii?ea A3-34” ca?aeii ?aeiiaiaeaoe?e
TH.?.?aaiiaa, I.I.Iiai?aethea (1990).

?acoeueoaoe aeine?aeaeaiiy oa ?o iaaiai?aiiy

Aaaiio /anoeo na?aae oai?eo neeaee ae?oe a?eii 3-9 i?n. (41,48%).
I?ia?aeia i?noea a ao?ieia?/i?e no?oeoo?? naeueiiiaeueico caeiaea S.
typh?murium — 95,56%. 67,41% ae?oae caoai??ee o ceiiai-aaniyiee ia??iae.
Aea? o?aoeie iaoe??io?a ?io?eoaaeeny o e?eoaaeueieo caeeaaeao, iiiaae
80% c ieo noaiiaeee iaiiaeyoa. On? aeiaaeee aioo??e?ea?iyiiai
?io?eoaaiiy coiiaeai? S. typh?murium, aiii oa?aeoa?ecoaaeinue o?eaaeei
(aei 10 ae?a) ?ieoaaoe?eiei ia??iaeii. Io?eiai? ?acoeueoaoe iiaeia
iiynieoe iecueeei ??aiai ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio o ae?oae
oeueiai a?eo (Ae.A.Noaoaie, TH.A.Aaeueoeuaa, 1997).

Aano?i-?ioanoeiaeueio oi?io naeueiiiaeueico ae?aaiinoiaaii o 91,85%
ae?oae. Ia?aaaaeaee neiioiie eie?oo. Caeaaeii oyaeeino? ia?aa?ao
caoai?thaaiiy an?o oai?eo aoei iiae?eaii ia 3 a?oie. A a?oio ?c eaaeei
ia?aa?aii caoai?thaaiiy aa?eoei 11,11%, na?aaeiueioyaeeei — 51,85%,
oyaeeei — 37,04% oai?eo. Aeaii aeaoaeueio ee?i?/io oa?aeoa?enoeeo
iaoe??io?a ?c ??ciei nooiaiai oyaeeino? caoai?thaaiiy. O an?o aeyaeaii
ia?aiaoyaeaiee i?aii?a?aeiee oii. Aeey eaaeiai ia?aa?ao caoai?thaaiiy ia
aoee oa?aeoa?i? ae?aaeai? i?iyae neiae?iio ?ioieneeaoe??, ?aoeeaeeae,
oi?ioaaiiy aaeoa??iiin?enoaa, aaiieie?o. A ee?i?/i?e ea?oei? ia?aaaaeaee
aeeniaine/i? i?iyae. Naeueiiiaeueic na?aaeiuei? oyaeeino?
noi?iaiaeaeoaaany ?aoeeaeeaoth/ei ia?aa?aii o 23% oai?eo; oyaeeiai
nooiaiy — o 28%. A?aenioie oi?ioaaiiy aaeoa??iiin??a ia?inoaa
i?iii?oe?eii oyaeeino? caoai?thaaiiy. A?i neeaa 7,14% i?e
na?aaeiueioyaeeiio oa 14% — i?e oyaeeiio naeueiiiaeueic?. Aeey
caoai?thaaiiy na?aaeiueiai oa oyaeeiai nooiai?a oa?aeoa?iei aoei, ii?yae
?c aeeniaine/iei neiae?iiii, i?e?aeiaiiy neiae?iio aiaeiaaiii?
?ioieneeaoe??, ui noi?iaiaeaeoaaany aoyaiaiiyi o iaoieia?/iee i?ioean
on?o i?aai?a oa nenoai. O oyaeeeo aeiaaeeao a?i oi?ioaaa ee?i?/io
ea?oeio caoai?thaaiiy, a?aenoaath/e aeeniaine/i? i?iyae ia ae?oai?yaeiee
ieai.

Aeey ioe?iee ae?aaeaiino? NA? on?i a?oiai oai?eo i?iaaaeaii aecia/aiiy
INI o ieaci? e?ia?, A?? oa i?ae?aooiie E?? o aino?ee ia??iae
caoai?thaaiiy.

Oaaeeoey 1

Iieacieee aiaeiaaiii? ?ioieneeaoe?? o oai?eo ia naeueiiiaeueic o aino?ee
ia??iae caoai?thaaiiy, (Im)

Oyaee?noue caoai?thaaiiyINI1, oi.iae.INI2, yi.iae.A??, %E??Eaaea,
n=10190,006,29367,0014,738,021,100,460,07Na?aaeiy,
n=37259,478,37488,9414,941,070,661,460,17Oyaeea,
n=34278,1714,1500,4632,241,771,172,540,37Caei?ia?,
n=44170,003,22306,902,625,521,100,460,06

I?ei?oea: –– iieaciee aeinoia??iee o ii??aiyii? ?c a?oiith caei?iaeo

I?e eaaeiio ia?aa?ao caoai?thaaiiy ai?no INI1 ia?aaeuoaaa ii?io o 1,12
?ace, na?aaeiueioyaeeiio — o 1,53, oyaeeiio — o 1,64 (?<0,001); oe? iieacieee aeinoia??ii ??cieeenue i?ae niaith. Eiioeaio?aoe?y INI2 oaeiae aoea aeuith i?iii?oe?eii oyaeeino? caoai?thaaiiy, ia?aaeuoth/e ii?io a?aeiia?aeii o 1,20; 1,59; 1,63 ?ace (?<0,01). Ai?no INI2 i?e eaaeiio ia?aa?ao naeueiiiaeueico aeinoia??ii a?ae??ciyany a?ae oaeiai o oai?eo ?c na?aaeiueioyaeeei oa oyaeeei ia?aa?aii oai?iae (?<0,001). Aeine?aeaeaiiy A?? aeaei noiaeee ?acoeueoao, eiai ai?no aoa aeuei o 1,49; 1,61; 1,64 ?ace ii??aiyii c eiio?ieueiith a?oiith (?<0,001), aeinoia??iith aoea ??cieoey o ae?oae ?c eaaeei oa na?aaeiueioyaeeei, eaaeei oa oyaeeei ia?aa?aii caoai?thaaiiy (?<0,05;<0,02). E?? i?e eaaeiio ia?aa?ao aei??aithaaa eiio?ieueiiio iieacieeo, ia?aaeuoaaa ii?io o 3,20; 5,52 ?ac (?<0,001) i?e na?aaeiueioyaeeeo oa oyaeeeo aeiaaeeao, i?iii?oe?eii oyaeeino? oai?iae, aeinoia??ii a?ae??ciyth/enue i?ae niaith (?<0,001). Aeyaeaii iiceoeaiee ei?aeyoe?eiee ca'ycie ia?inoaiiy aeuaaeacaieo aaee/ei a?aeiia?aeii oyaeeino? ia?aa?ao caoai?thaaiiy (?<0,01). Oaeei /eiii, aiae?c ?acoeueoao?a cana?ae/o? iayai?noue NA? o oai?eo ia naeueiiiaeueic ae?oae, aeeaeia yeiai aecia/a?oueny oyaee?noth ia?aa?ao caoai?thaaiiy. Ae?aaeai?noue NA?, a naith /a?ao, aecia/a? ee?i?/io ea?oeio, ia?aa?a oa iane?aeie caoai?thaaiiy. ??aaiue aiaeioieneeico coiiaeaiee iaoiaaiiith ae??th i?e?ii?aai?ci?a, ?o oienei?a, aeeaieeie iaoaaie?/ieie ii?ooaiiyie oa cieaeaiith ooieoe??th i?aai?a ae?i?iaoe??. Eaai?aoi?i? iieacieee aiaeiaaiii? ?ioieneeaoe?? i?aeoaa?aeaeothoue ?o caeaaei?noue a?ae ae?aaeaiiino? caoai?thaaiiy oa iiaeooue neoaeeoe ia'?eoeaiei e?eoa???i oyaeeino? eiai ia?aa?ao. ?icaeoie ?ioaeoe?eiiai i?ioeano, oyaee?noue eiai ia?aa?ao oa iane?aeee aaaaoi a /iio caeaaeaoue a?ae noaio ?ioiieia?/iiai caoenoo i?aai?cio (H.Hahn, 1983). Ca ?acoeueoaoaie aeanieo aeine?aeaeaiue aeyaeaii nooo?aa i?eai?/aiiy O-ee?oeiii? eaiee ?ioi?oaoo o ianoaaeaieo iaiiaeyo (?<0,001). Ii?yae ?c iecueeith a?aeiiniith oa aaniethoiith e?euee?noth O-e?ioioeeo?a, 33,9±0,55% i?ioe 53,77±3,06% oa 1,31±0,08o109/e i?ioe 1,83±0,03o109/e (?<0,001), i?inoaaeo?oueny aeinoia??ii aenieee aaniethoiee (1,46±0,12o109/e i?ioe 0,61±0,23o109/e) oa a?aeiiniee (43,37±1,23% i?ioe 27,85±3,05%) ai?no iaaeeoa?aioe?eiaaieo ee?oei (?<0,001). I?e aiae?c? eiioeaio?aoe?? ?ioii?aaoeyoi?ieo O-ee?oei ca?a?no?iaaii aeinoia??ii iecueeee ??aaiue O?-?OE (26,78±0,41% i?ioe 40,69±2,22%) ? O/-?oe (6,92±0,26% i?ioe 14,46±1,0%), o ii??aiyii? c eiio?ieai (?<0,001). ?ioii?aaoeyoi?iee ?iaeaen noaiiaea 4,04±0,12, cia/ii ia?aaeuoth/e eiio?ieueiee iieaciee - 2,79±0,22 (?<0,001). Aeinoia??ii? ??cieoe? a?aeiia?aeii oyaeeino? ia?aa?ao caoai?thaaiiy ia ciaeaeaii. O ae?oae, noa?oeo 1 ?ieo, oaeiae aeyaeaii nooo?aa i?eai?/aiiy O-ee?oeiii? eaiee ?ioi?oaoo (?<0,001). Ii?yae ?c iecueeith a?aeiiniith e?euee?noth O-e?ioioeeo?a, 35,22±0,76% i?ioe 53,5±1,71% (?<0,001), oa aaniethoiith: 0,76±0,08o109/e i?ioe 1,29±0,12o109/e, i?inoaaeo?oueny aeinoia??ii aenieee aaniethoiee (0,95±0,12o109/e i?ioe 0,61±0,23o109/e) oa a?aeiiniee (43,5±1,31% i?ioe 25,10±1,41%) ai?no iaaeeoa?aioe?eiaaieo ee?oei (?<0,001). I?e aiae?c? eiioeaio?aoe?? ?ioii?aaoeyoi?ieo O-ee?oei ca?a?no?iaaii aeinoia??ii iecueeee ??aaiue O?-?OE (28,33±0,34% i?ioe 39,40±1,58%) ? O/-?oe (6,88±0,27% i?ioe 15,6±1,10%), o ii??aiyii? c eiio?ieai (?<0,001). ?ioii?aaoeyoi?iee ?iaeaen noaiiaea 4,17±0,15, cia/ii ia?aaeuoth/e eiio?ieueiee iieaciee - 2,5±0,39 (?<0,001). Aeinoia??ii? ??cieoe? a?aeiia?aeii oyaeeino? ia?aa?ao caoai?thaaiiy ia ciaeaeaii. Oaeei /eiii, o oai?eo ia naeueiiiaeueic ae?oae aeyaeaii aeai?an?th ee?oeiii? eaiee ?ioi?oaoo, ui coiiaeaii ae??th aiaeioieneio naeueiiiae, aieeaii aiaeiaaiii? ?ioieneeaoe?? ia ?aoeaioi?io aeoeai?noue e?ioioeeo?a. Ooieoe?iiaeueia iaaeinoaoi?noue O-eaiee ?ioi?oaoo i?iyaey?oueny aeao?oeeoii noi?ani?ii? oa oaeia?ii? aeoeaiino? ?c cnoaii ?ioii?aaoeyoi?iiai ?iaeaeno a a?e oaeia?iiai aoaeoo. Iaaei??iee aeeeae o e?ia iaeieiiiaoaioieo o ?ioiieia?/iiio a?aeiioaii? e?ioioeeo?a iiaeia iiynieoe aeoea?caoe??th i??eiiiaco aaeoa??aeueiith ?ioaeoe??th oa aiaeioieneiaie ca ?aooiie cieaeaiiy ooioe?? O-noi?ani??a (A.E.Niieyaei e niaao., 1996). O iaiiaeyo a?aeiinia eiioeaio?aoe?y AAN-?OE aei??aithaaea eiio?ieuei?e, a oie /an, ye ?o aaniethoia eiioeaio?aoe?y aoea aenieith. Ii?yae c oeei, a?aei?/aii aeinoia??ii aenieee ??aaiue Ig I, iaeaea aaea?/? aeuee ca eiio?ieueiee iieaciee - 1,98±0,13 a/e i?ioe 0,88±0,29 a/e (?<0,001). Ai?no Ig G, ii??aiyii ?c eiio?ieai, aoa aeuei - 7,28±0,26 a/e i?ioe 6,26±0,5 a/e (?<0,001). Eiioeaio?aoe?y Ig A - ieae/ith: 1,04±0,07 a/e i?ioe 1,47±0,12 a/e (?<0,02). O ae?oae, noa?oeo 1 ?ieo, a?aei?/aii aeinoia??ii iecueeo eiioeaio?aoe?th AAN-?OE (6,0±0,37% i?ioe 8,58±0,41%), ?<0,001. Ii?yae c oeei, a?aei?/aii aeinoia??ii aenieee ??aaiue Ig I, iaeaea aaea?/? ia?aaaaeath/ee eiio?ieueiee - 2,22±0,15 a/e i?ioe 1,06±0,52 a/e (?<0,001). Ai?no Ig G ii??aiyii ?c eiio?ieai - iecueeee: 6,87±0,15 a/e i?ioe 9,8±0,32 a/e (?<0,001). Eiioeaio?aoe?y Ig A aoea iecueeith - 1,16±0,08 a/e i?ioe 1,52±0,12 a/e. Aiae?c ?ioiiaeiaoe?iiaiai niaeo?o na?ae/eoue, ui i?e naeueiiiaeueic?, ye ? o aeiaaeeo ?ioeo ?ioaeoe?eieo caoai?thaaiue a ia?oo /a?ao aeoeaothoueny A-e?ioioeeoe, ui a?aeiia?aeathoue ca neioac Ig I (TH.Ae.Eaaai e niaao., 1989; A.I.ss?eia e niaao, 1992). Aaeoa??eia ?iaac?y naeueiiiaeaie i?ecaiaeeoue aei ciaioaiiy eiioeaio?aoe?? oa ii?iaeueiiai ni?aaaeiioaiiy iae?aaoii? i?e?ioei?e (a?o?aei-, eaeoiaaeoa??e, ii?iaeueiioa?iaiooth/eo eeoeiaeo iaee/ie), ii?yae ?c ia?inoaiiyi /enea oiiaiiiaoiaaiieo oa ?yaeo iaoiaaiieo aaeoa??e, a?eae?a. Aeena?ioe/i? ci?ie ?a?no?othoueny o 100% aeiaaee?a. Ianoaaeaiiy i?e?iaiiai iaecaaeo oianoi? eeoee aeyaeei, ui oyaeeee ia?aa?a caoai?thaaiiy noi?iaiaeaeoaaany ae?aaeaieie ci?iaie o e?euee?niiio oa ye?niiio neeaae? i?e?ioei?e, o ii??aiyii? ?c eaaeei oa na?aaeiueioyaeeei. Ii?yae ?c cieaeaiiyi ai?noo iiei/iieenei?-, a?o?aeioei?e, ci?iith /enea ii?iaeueiioa?iaiooth/eo eeoeiaeo iaee/ie, a?aei?/aii, ui i?e aeenaaeoa??ic? ?? nooiaiy o a?eueoiai /enea oai?eo c?inoaea eiioeaio?aoe?y iaoiaaiii? oa oiiaiiiaoiaaiii? oei?e ?iaeeie Enterobacteriacea (?<0,05), c'yaeeenue a?eaee ?iaeo Candida oa aaeoa??? ?iaeo I?ioae (?<0,001). Ine?eueee NA? caeia? i?ia?aeia i?noea o ?icaeoeo iaoieia?/ieo ci?i a i?aai?ci? oai?eo ia naeueiiiaeueic - oi iaei??th ?c oiia e?eoaaiiy ? aeaoieneeaoe?y i?aai?cio. I?ioyaii inoaii?o ?ie?a a?naiae aeaoieneeoth/eo cania?a cia/ii ?icoe?eany ca ?aooiie aioa?aeueiiai aeei?enoaiiy aaeni?aaio?a. Oea iaeei ?c no/anieo iaoiae?a aeaaaeaiiy c i?aai?cio aeci- oa aiaeioienei?a, i?iaeoe?a niioai?aiiai iai?io. A?i ia?iaaceaiee oa eaaeiaeinooiiee, o ii??aiyii? c ?ioeie iaoiaeaie ni?aoe??. Inoaii?i /anii oaaao ee?i?oeeno?a oa aenia?eiaioaoi??a i?eaa?oathoue e?aii?ei?aai?/i? ni?aaioe. Na?aae aenieiaeenia?nieo e?aiiacai?a iaea?eueoi? oaaae caneoaiao? iie?ni?a. A?i ia? aenie? aaeni?aoe?ei? aeanoeaino? uiaei a?ieia?/ii aeoeaieo ?a/iaei a?eeiai? i?e?iaee (aiaei- ? aecioienei?a, oa?iaio?a), i?e?ii?aai?ci?a. Ae??aiiaeenia?ni?noue ni?ey? eaaeino? eiai i?eeiio ae?oueie, iniaeeai iaiiaeyoaie. Oea, a oaeiae oa, ui o ii??aiyii? c ?ioeie ni?aaioaie iie?ni?a ia? aeuo ni?aoe?eio caeaoi?noue uiaei aini?oaeueieo ooai?a aaeoa??e, noaei aieiaiei iiooiaoii aeey aeei?enoaiiy i?aia?aoo o e?eoaaii? aioo??e?ea?iyieo ?ioaeoe?e. A ee?i?eao Oe?a?ie i?iaiaeeoueny oe?iea ai?iaaoe?y iiaiai aeaoieneeoth/iai caniao a?oie iie?ni?a?a – “Neeea?ae I”. O aeine?aeaeoaaieo a?oiao oai?eo ia naeueiiiaeueic ae?oae ??ciiai a?eo aea/aee aeeiai?eo ee?i?/ieo i?iya?a naeueiiiaeueico, iniiaieo iieaciee?a aiaeiaaiii? ?ioieneeaoe??, ?ioiiiai noaoono, i?e?iaiiai iaecaaeo eeoe?aieea a caeaaeiino? a?ae canoiniaaii? oa?ai??. Ae?oe eiaeii? a?oie aoee ?iciiae?eai? ia i?aea?oie: ? i?aea?oia io?eioaaea caaaeueiii?eeiyoee eiiieaen e?eoaaeueieo caoiae?a; ?? - a eiiieaeniiio e?eoaaii? io?eioaaea “Neeea?ae I” c ?ic?aooieo 75 ia/ea iane o?ea ia aeiao o 4 i?eeiie i?e eaaeiio nooiai? caoai?thaaiiy i?ioyaii 5 ae?a, 100 ia/ea iane ia aeiao a 4 i?eeiie i?ioyaii 5 ae?a i?e na?aaeiueioyaeeiio nooiai? oa 100 ia/ea iane ia aeiao a 4 i?eeiie i?ioyaii 7 ae?a - i?e oyaeeiio. Ca ?acoeueoaoaie aeine?aeaeaiue anoaiiaeaii, ui aeeth/aiiy aioa?ini?aoe?? a eiiieaenia e?eoaaiiy oai?eo ia naeueiiiaeueic ae?oae ia? iiceoeaiee ee?i?/iee aoaeo. Oae, o oai?eo, ui io?eioaaee “Neeea?ae I”, o ii??aiyii? c ia?oith a?oiith, ia 1-2 aeiae oaeaeoa cieeaee i?iyae ?ioieneeaoe?? (aa?y/ea, iiaaia naiiii/oooy, cieaeaiee aiaoeo), ia 1,5-2 aeiae oaeaeoa eoioaaeanue ae?a?ay, oaeaeoa ianooiaea no?eea ii?iae?caoe?y aeii?iaeiaiue, ciaiooaaeanue e?euee?noue aaeoa??iiin??a o 3-4 ?ace, nei?ioeeanue o?eaae?noue aaeoa??iaeae?eaiiy oa e?euee?noue ?aoeeaeea?a caoai?thaaiiy. Ae?aaeai?noue iiceoeaieo ci?i ia caeaaeaea a?ae oyaeeino? caoai?thaaiiy oa a?eo oai?eo. Aecia/aiiy aeeiai?ee iieaciee?a aiaeioieneeico a on?o aeine?aeaeoaaieo a?oiao iieacaei ?o cieaeaiiy, a ii??aiyii? c iieacieeaie aei e?eoaaiiy, iacaeaaeii a?ae aeaeo oa?ai??. I?ioa, a?eueo aaaii? ci?ie niinoa??aaeenue ia oe? aioa?ini?aoe??. Oae, ai?no INI1 o ieaci? oai?eo ?c eaaeei ia?aa?aii caoai?thaaiiy ii?iae?coaaany i?ae aieeaii i?iaaaeaiiai e?eoaaiiy (168,33±11,20 oi.iae. oa 141,14±13,97 oi.iae.), cieaeoth/enue ieae/a eiio?ieueiiai ??aiy i?ney aioa?ini?aoe??, a INI2 cieaeoaaany (330,17±19,55 oi.iae. oa 309,42±30,32 oi.iae.), iaaeeaeath/enue aei eiio?ieueiiai iieacieea o ae?oa?e i?aea?oi?. O ae?oae ?c oyaeeei oa na?aaeiueioyaeeei ia?aa?aii caoai?thaaiiy ai?no INI iaio o?aeoe?e cieaeoaaany i?ae aieeaii aioa?ini?aoe?? aeinoia??ii oaeaeoa, o ii??aiyii? ?c o?aaeeoe?eiei e?eoaaiiyi (?<0,05). A?aeiia?aeii, i?e na?aaeiueoyaeeiio naeueiiiaeueic? INI1 cieaeoaaeenue aei 222,55±11,29 oa 193,7±8,82 oi.iae., a INI2 - aei 400,45±17,2 oa 375,77±14,32 oi.iae., ia nyaath/e eiio?ieueiiai iieacieea. O oyaeeeo aeiaaeeao INI1 ia oii? caaaeueiii?eeiyoiai e?eoaaiiy cieceany aei 223,54±10,71 oi.iae., aioa?ini?aoe?? - aei 186,4±13,44 oi.iae., a INI2 - aei 414,54±19,13 oa 370,6±17,66 oi.iae. a?aeiia?aeii. Oaeaeoa cieaeoaaany A?? i?ae aieeaii aioa?ini?aoe?? o an?o a?oiao, aeinoia??ii a?ae??ciyth/enue a?ae o?aaeeoe?eiiai e?eoaaiiy o ae?oae ?c na?aaeiueioyaeeei oa oyaeeei ia?aa?aii oai?iae, iniaeeai iii?oiee ?acoeueoao o iaoe??io?a ?c oyaeeei nooiaiai naeueiiiaeueico. O ieo A?? cieceany aei 31,18% ia oii? aioa?ini?aoe??, o ii??aiyii? ?c o?aaeeoe?eiei e?eoaaiiyi (37,21%) - ?<0,001. O an?o a?oiao aeyaeaii cieaeaiiy E?? ieae/a 1,0. Ii?iae?caoe?y oeueiai iieacieea a?aeaoeanue o ae?oae ?c eaaeei ia?aa?aii caoai?thaaiiy ?c cieaeaiiyi ieae/a aeo?aeieo aaee/ei o iaio i?aea?oiao (0,38±0,07 oa 0,27±0,07), o aeiaaeeo na?aaeiueioyaeeiai oa oyaeeiai naeueiiiaeueico ??aaiue E?? ua caeeoaany i?aeaeuaiei (0,62±0,14 ? 0,54±0,10) oa (0,69±0,16 ? 0,64±0,08) a?aeiia?aeii. Aeeth/aiiy "Neeea?aeo I" o eiiieaen o?aaeeoe?eii? oa?ai?? ni?ey? iie?ioaiith ooieoe?iiaeueiiai noaio ee?oeiii? eaiee ?ioi?oaoo, ui i?iyaey?oueny aeinoia??iei ca?eueoaiiyi caaaeueii? e?eueeino? O-e?ioioeeo?a ye o iaiiaeyo (40,64±0,83 ? 38,76±0,58%), oae ? o ae?oae, noa?oeo 1 ?ieo, (42,8±1,07 ? 41,89±1,48%) oa ?o noaiiioeyoe?e: O?-?OE o iaiiaeyo (30,27±0,46 ? 29,41±0,47%), o noa?oeo: 31,11±0,99 ? 32,09±2,3%; O/-?OE o iaiiaeyo (10,48±0,37 ? 9,23±0,35%), o noa?oeo: 10,78±0,57 ? 10,8±0,57%; ciaioaiiyi 0-ee?oei o iaiiaeyo (34,05±1,1 ? 37,71±1,19%), oa 32,56±1,65 ? 33,54±1,5% o noa?oeo a ii??aiyii? c aino?ei ia??iaeii oai?iae, c aeinoia??ii aeuith aoaeoeai?noth, o ii??aiyii? ?c o?aaeeoe?eiei e?eoaaiiyi. A?aei?/aii oaeaeoee i?e??no O/-?OE (?<0,02), iaaeeaeaiiy ?ioii?aaoeyoi?iiai ?iaeaeno aei ii?iaeueieo aaee/ei o iaoe??io?a, ui io?eioaaee aioa?ini?aaio (2,92±0,08 i?ioe 3,28±0,11 o ae?oae aei 1 ?ieo, oa 2,92±0,09 i?ioe 3,04±0,12 o ae?oae, noa?oeo 1 ?ieo). Ii?yae c oeei aeinoia??ii cieaeoaaeanue eiioeaio?aoe?y iaaeeoa?aioe?eiaaieo e?ioioeeo?a (?<0,02). Ia a?aei?/aii iiceoeaiiai aoaeoo ia ai?no AAN-?OE i?ney aioa?ini?aoe?? o iaoe??io?a, noa?oeo 1 ?ieo, yeee iaa oaiaeaioe?th aei c?inoaiiy o ii??aiyii? c aino?ei ia??iaeii oai?iae. O iaiiaeyo aiane?aeie eiiieaeniiai canoinoaaiiy aioa?ini?aoe?? oeae iieaciee caeeoaany noaeei, a i?ney o?aaeeoe?eiiai e?eoaaiiy aei??aithaaa eiio?ieueiiio. Aioa?ini?aoe?y ni?eyea iiaeaeueoiio cieaeaiith ai?noo Ig G o ae?oae noa?oi? a?eiai? a?oie, ii??aiyii ?c aino?ei ia??iaeii caoai?thaaiiy. O iaiiaeyo ??aaiue Ig G i?ae aieeaii aioa?ini?aoe?? iaa oaiaeaioe?th aei cieaeaiiy a a?e eiio?ieueiiai iieacieea, Ig A – ia?inoaa, ii?iae?coth/enue i?e o?aaeeoe?eiiio e?eoaaii?. O ae?oae, noa?oeo 1 ?ieo, oeae iieaciee i?iaeiaaeoaaa cieaeoaaoeny, iniaeeai ia oii? aioa?ini?aoe?? (1,04±0,13 a/e i?ioe 1,4±0,09 a/e). Aoei iii?oiei iaae?iiy ai?noo ?g M aei 1,44±0,12 a/e, o ii??aiyii? ?c 1,79±0,21 a/e o e?eiaaieo o?aaeeoe?eii (?>0,1). O iaio aeiaaeeao iieaciee ia aeinyaaa
ii?ie (1,06±0,52 a/e) o iaoe??io?a oeueiai ae a?eo. O iaiiaeyo
eiioeaio?aoe?y ?g M cieaeoaaeanue i?eaeecii ia 20 a?aenioe?a ia caeaaeii
a?ae aeaeo i?iaaaeaiiai e?eoaaiiy, aea ana ua a?ae??ciyth/enue a?ae
eiio?ieueiiai iieacieea (0,88±0,29 a/e).

Oaeei /eiii, aioa?ini?aoe?y aieeaa? iiceoeai ia aoii?aeueio eaieo
?ioi?oaoo, cieaeoth/e eiioeaio?aoe?th IgM oa IgA, ui ni?ey? iie?auaiith
ooieoe?iiaeueieo oa?aeoa?enoee i?aai?a aeaoieneeaoe??.

Ni?aaioe, iniaeeai e?aii?ei?aai?/ii? i?e?iaee, iath/e aea??eiao ae?th ii
a?aeiioaiith aei aaeoa??e oa ?o oienei?a, ie i?eai?/othoue ii?iaeueio
i?e?ioei?o eeoe?aieea, a ni?eythoue ?? oaeaeoiio a?aeiiaeaiith.

I?iaaaeaia iiaoi?ia aeine?aeaeaiiy i?e?iaiiai iaecaaeo eeoe?aieea o
ae?oae, ui io?eioaaee “Neeea?ae I” aeyaeei ciaioaiiy ae?aaeaiino?
aeenaaeoa??ico o 47,06±12,11% ia i?ioeaaao 21,05±9,35% i?e
o?aaeeoe?eiiio e?eoaaii?. Ii?iae?caoe?y a?ioeaiico ianooieea o
31,18±11,94% oai?eo, oiae? ye o ? i?aea?oi? oeueiai ia a?aeaoaaeiny.
Aoea iaioith /anoioa iiaoi?iiai aaeoa??iaeae?eaiiy naeueiiiae
(23,53±10,29% i?ioe 42,11±11,33%). O iaoe??io?a ?? i?aea?oie oaeaeoa, o
ii??aiyii? c ia?oith, a?aeiiaethaaany iaeaaeiee ai?no iae?aaoii?
i?e?ioei?e. O ieo, i?ney i?iaaaeaiiai e?eoaaiiy, aaeoa??? ?iaeo I?ioae
i?iaeiaaeoaaee aeae?eyoenue o 1/3, oiae? ye o ? i?aea?oi? — o 1/2, o
a?eueo?e eiioeaio?aoe??. A a?eaee ?iaeo Candida — o 3/4 oa 1/3
a?aeiia?aeii.

Iaaaaeai? aeai? iaa?oioiaothoue iaiao?aei?noue aeeth/aiiy a eiiieaenio
oa?ai?th oai?eo ia naeueiiiaeueic ae?oae ??ciiai a?eo e?aii?ei?aai?/iiai
aioa?ini?aaioa “Neeea?ae I”, yeee, ii?yae ?c aeaoieneeaoe?eiith,
?ioiiei?eaoth/ith ae??th, ia? iiceoeaiee aieea ia i?e?iaiee iaecaae
oianoi? eeoee.

?yae oi?eaeueieo ni?aoe?eieo aeanoeainoae oeueiai ni?aaioa oa eiai aeea
ia iieacieee, ui aea/aeeny, aeicaieythoue ?aeiiaiaeoaaoe “Neeea?ae I”
aei aeoeaiiai aeei?enoaiiy o e?eoaaii? oai?eo ia aino?? eeoeia?
?ioaeoe?? ae?oae, cie?aia naeueiiiaeueic.

AENIIAEE

1. I?ia?aeiei neiae?iiii o oai?eo ia naeueiiiaeueic ae?oae ? neiae?ii
aiaeiaaiii? ?ioieneeaoe??. Eiai ee?i?/i? i?iyae aeyaeaii o 66,7% oai?eo
ia naeueiiiaeueic eaaeiai nooiaiy, o 81,4% — na?aaeiuei? oyaeeino? oa o
100% — oyaeeiai. Iaeaeuee ??aaiue aiaeiaaiii? ?ioieneeaoe??
niinoa??aa?oueny o oai?eo ?c oyaeeei ia?aa?aii caoai?thaaiiy.

2. E??i ee?i?/ieo iciae aeey neiae?iio aiaeiaaiii? ?ioieneeaoe??
aeanoea? ia?aee?i?/i? i?iyae, aeyaeai? o an?o oai?eo. Ia?ea?aie
neiae?iio aiaeiaaiii? ?ioieneeaoe?? ?: ??aaiue iieaeoe na?aaeiuei? iane
o ieaci? e?ia? oai?eo, a?eo?ioeeoa?iee, eaeeioeeoa?iee ?iaeaene
?ioieneeaoe??.

3. A oiiaao aiaeiaaiii? ?ioieneeaoe?? a i?aai?ci? oai?eo ia
naeueiiiaeueic ae?oae nooo?ai ii?ooo?oueny ?ioiiee caoeno. I?i oea
na?ae/aoue ci?ie ye o ee?oeii?e, oae ? a aoii?aeuei?e eaieao ?ioi?oaoo.
Ca?a?no?iaaii iecueeee ai?no caaaeueii? e?eueeino? O-e?ioioeeo?a,
aenieee ??aaiue 0-ee?oei, ii?ooaiiy ni?aa?aeiioaiiy ?ioii?aaoeyoi?ieo
O-e?ioioeeo?a ia ei?enoue O-oaeia??a. Ci?ie o ?ioiiaeiaoe?iiaiio niaeo??
i?iyaeeeny aenieei ??aiai Ig M ii?yae ?c iecueeith eiioeaio?aoe??th Ig A
oa Ig G. Ii?ooaiiy ?ioiiiai caoenoo iiaeooue neoaeeoe aeiiii?aeieie
e?eoa?yie ae?aaiinoeee aiaeioieneeico.

4. O oai?eo ia naeueiiiaeueic ae?oae niinoa??aa?oueny ii?ooaiiy
i?e?iaiiai iaecaaeo eeoe?aieea ca ?aooiie i?eai?/aiiy iae?aaoii?
i?e?ioei?e, ?inoo oiiaiiiaoiaaiieo oa iaoiaaiieo i?e?ii?aai?ci?a.
Ae?aaeai?noue aeena?ioe/ieo ci?i ia?inoa? a?aeiia?aeii oyaeeino?
ia?aa?ao caoai?thaaiiy.

5. A?aoiaoth/e ?i?oe?aeueio ?ieue oienei?a naeueiiiae o ?icaeoeo
neiae?iio aiaeiaaiii? ?ioieneeaoe?? o oai?eo ia naeueiiiaeueic ae?oae,
aieea ?o ? oienei?a aiaeiaaiiiai iioiaeaeaiiy ia an? nenoaie oa i?aaie
o?aaeaiiai i?aai?cio, iiina?aaeeiaaiee aieea ia ?ioiio nenoaio,
i?e?iaiee iaecaae eeoe?aieea, iaoiaaiaoe/ii iaa?oioiaaiith ? ?o
ae?i?iaoe?y oeyoii aioa?ini?aoe??.

6. Canoinoaaiiy eiiieaenii? oa?ai?? ?c aeeth/aiiyi aioa?ini?aaioo
«Neeea?ae I» o e?eoaaii? oai?eo ia naeueiiiaeueic ae?oae ni?ey?
ciaioaiith ee?i?/ieo i?iya?a oai?ae: nei?i/aiith o?eaaeino? aa?y/ee,
ae?a?a?, neiioii?a ?ioieneeaoe??. Ii?yae c oeei — aoaeoeaii cieaeo?
eaai?aoi?i? iciaee aiaeiaaiii? ?ioieneeaoe??, ?, oei naiei, ni?ey?
onoiaiith aeao?oeeoo O-ee?oeiii? eaiee ?ioi?oaoo, cieaeaiith
eiioeaio?aoe?? ?ioiiaeiaoe?ia I, nei?i/aiith o?eaaeino?
aaeoa??iaeae?eaiiy, a?aeiiaeaiith i?e?iaiiai iaecaaeo oianoi? eeoee oa
ciaioaiith a?aenioea ?aeiiaaeanoeaioieo aaeoa??iiin??a. Oea coiiaeth?
nei?i/aiiy oa?i?io noaoe?iia?iiai e?eoaaiiy, ii??aiyii ?c o?aaeeoe?eiei
e?eoaaiiyi.

I?AEOE*I? ?AEIIAIAeAOe??

1. Aeey ioe?iee ae?aaeaiino? neiae?iio aiaeiaaiii? ?ioieneeaoe??,
aeeaeie iaoaaie?/ieo c?ooaiue o aeeoy/iio i?aai?ci? oa eiio?ieth
aoaeoeaiino? eiai ei?aeoe?? ?aeiiaiaeo?oueny aecia/aoe ai?no iieaeoe
na?aaeiuei? iane o ieaci? e?ia?, a?eo?ioeeoa?iee, eaeeioeeoa?iee
?iaeaene ?ioieneeaoe??.

2. Aeey aecia/aiiy nooiaiy ii?ooaiiy ?ioiiiai caoenoo, i?e?iaiiai
iaecaaeo oianoi? eeoee oa ?o ei?aeoe?? ae?oyi, oai?ei ia naeueiiiaeueic,
?aeiiaiaeo?oueny aeine?aeaeaiiy noaio ee?oeiii? oa aoii?aeueii? eaiie
?ioi?oaoo oa i?e?ia?ioeaiico oianoi? eeoee.

3. Aeey i?enei?aiiy ? iiaiioe ei?aeoe?? neiae?iio aiaeiaaiii?
?ioieneeaoe??, ?ioiieia?/ieo c?ooaiue, aeena?ioeaiico oianoi? eeoee a
eiiieaenia e?eoaaiiy oai?eo ia naeueiiiaeueic ae?oae ?aeiiaiaeo?oueny
i?ecia/aoe aioa?ini?aaio «Neeea?ae I». ?aeiiaiaeiaaia aeica i?e eaaeiio
ia?aa?ao caoai?thaaiiy — 75 ia/ea iane o?ea ia aeiao o 4 i?eeiie
i?ioyaii 5 ae?a, i?e na?aaeiueioyaeeiio — 100 ia/ea iane o?ea ia aeiao o
4 i?eeiie i?ioyaii 5 ae?a, i?e oyaeeiio — 100 ia/ea iane o?ea ia aeiao a
4 i?eeiie i?ioyaii 7 ae?a. Aeey iiia?aaeaeaiiy aaeni?aoe?? oa?/iaeo
i?iaeoeo?a, ia?i?aeueieo e?ea?nueeeo cania?a aioa?ini?aaio ne?ae
i?ecia/aoe c ?ioa?aaeii 1,5 aiaeeie aei /e i?ney ?o i?eeiio.

4. Canoinoaaiiy «Neeea?aeo I» aeicaiey? ia 1,5-2 aeiae oaeaeoa eoioaaoe
ee?i?/i? i?iyae naeueiiiaeueico o ae?oae, ciaioeoe o?eaae?noue
aaeoa??iaeae?eaiiy, cieceoe a?aenioie aaeoa??iiin??a ?, oei naiei,
nei?ioeoe o?eaae?noue noaoe?iia?iiai e?eoaaiiy.

Nienie iioae?eiaaieo i?aoeue ca oaiith aeena?oaoe??

1. Ee?i?/ia oa?aeoa?enoeea oai?eo ia naeueiiiaeueic ae?oae a no/anieo
oiiaao // Iaae?ao??y, aeooa?noai oa a?iaeieia?y. — 1997. — ? 3. — N.
40-41.

2. A?eia? aniaeoe ?ioiieia?/ii? ?aaeoeaiino? o oai?eo ia naeueiiiaeueic
ae?oae // ?ioaeoe?ei? oai?iae. — 1997. — ? 2. — N. 27-28.

3. I?e?ioei?a eeoe?aieea o oai?eo ia naeueiiiaeueic ae?oae (a ni?aaao.
Ni?yi ?.N., Aeaena?iei E.?.)// Aanoiee i?iaeai aeie. e iaae. — 1997. —
aui.9. — C. 87-90.

4. E?eoaaiiy naeueiiiaeueco o ae?oae ?aiiueiai a?eo ca aeiiiiiaith
o?oini?aaioo ”ONA” (a ni?aaao. Ni?yi ?.N., Aeaena?iei E.?.)//
Iaoe.-i?aeo. eiio. Aei 100-??//y canioaaiiy EIAe?A?O ?i.
E.A.A?iiaoaanueeiai: oace aeii., 1996. — N. 53-53.

5. Iniaeeaino? ee?i?/iiai ia?aa?ao, noai ?ioiieia?/iiai caoenoo ? eiai
ei?aeoe?y o ae?oae ?aiiueiai a?eo, oai?eo ia naeueiiiaeueic // Ca.
noaoae OOO?O i?aen.iaoe.eiio. nooaeaio?a ? iieiaeeo a/aieo iaae. ?i-oo.
— Oa?iii?eue, 1996. — N. 84-87.

6. Noai i?e?iaeieia?? oianoiai eeoe?aieea o oai?eo ia naeueiiiaeueic
ae?oae // Iaoa??aee O? i?aen.iaoe.eiio. “Caeiaooee ee?i. oa aenia?ei.
Iaae.”: oace aeii. — Oa?iii?eue, 1997. — aei.2, /.??. — N. 478-480.

7. I?iaeaie naeueiiiaeueico o ae?oae ?aiiueiai a?eo (a ni?aaao. Eoaiaa
N.)// ? I?aeia?. iaae. eiia?an nooae. ? iieiaeeo a/aieo (oace aeii.),
18-22 o?aaiy 1997 ?., i. Oa?iii?eue. — Oa?iii?eue, 1997. — N. 232-232.

8. Aoaeoeai?noue canoinoaaiiy aioa?ini?aaioa “Neeea?ae I” o ei?aeoe??
neiae?iio aiaeiaaiii? ?ioieneeaoe?? o ae?oae, oai?eo ia naeueiiiaeueic
// ?? I?aeia?. iaae. eiia?an nooae. ? iieiaeeo a/aieo (oace aeii.), 6-8
o?aaiy 1998 ?., i. Oa?iii?eue. — Oa?iii?eue, 1998. — N. 149-149.

9. Ee?i?/iee aeina?ae canoinoaaiiy no/anieo i?ia?ioee?a o oa?ai??
ae?a?ae o ae?oae (a ni?aaao. Aeaena?iei E.?., Ni?yi ?.N., Aieyinueea
E.A., Ieeeothe N.I.) // Iaoa??aee V c’?caeo ?ioaeoe?ii?no?a Oe?a?ie
“Aeooaeuei? i?iaeaie ee?i?/ii? ?ioaeoieia??” (7-9 aeiaoiy 1998 ?.,
i.Oa?iii?eue). — Oa?iii?eue: Oe?iaaeeieaa, 1998. — N.82-84.

10. I?i ?ioiiiiaeoethth/ee aoaeo aioa?ini?aoe?? a ae?oae, oai?eo ia
naeueiiiaeueic // Iaoa??aee V c’?caeo ?ioaeoe?ii?no?a Oe?a?ie
“Aeooaeuei? i?iaeaie ee?i?/ii? ?ioaeoieia??” (7-9 aeiaoiy 1998 ?.,
i.Oa?iii?eue). — Oa?iii?eue: Oe?iaaeeieaa, 1998. — N.117-118.

11. Ee?i?ei-ai?aeai?ieia?/ia oa?aeoa?enoeea naeueiiiaeueico a ae?oae (a
ni?aaao. Ni?yi ?.N., Aeaena?iei E.?., Aieyinueea E.A., Ieeeothe N.I.) //
Iaoa??aee V c’?caeo ?ioaeoe?ii?no?a Oe?a?ie “Aeooaeuei? i?iaeaie
ee?i?/ii? ?ioaeoieia??” (7-9 aeiaoiy 1998 ?., i.Oa?iii?eue). —
Oa?iii?eue: Oe?iaaeeieaa, 1998. — N.186-188.

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