?INOEOOO I*IEO OAI?IA ? OEAIEIII? OA?AI??

?I. A.I.O?EAOIAA

OAeE 617.741-004.1-02:616.379-008.64-089.87+57.083.3

e a ? ? i i a

Iooo?e ?n?ao?e iaee

Ee?i?ei — ?ioiieia?/i? iniaeeaino? caiaeueii? ?aaeoe?? iea i?e
aeno?aeainoey?i?e aeno?aeoe?? eaoa?aeoe c ?iieaioaoe??th ?io?aieoey?ieo
e?ic o oai?eo ia oeoe?iaee ae?aaao

14.01.18. — I/i? oai?iae

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe

Iaeana — 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a ?inoeooo? i/ieo oai?ia ? oeaieiii? oa?ai?? ?i.
A.I.O?eaoiaa AII Oe?a?ie.

Iaoeiaee ea??aiee:

eaiaeeaeao iaaee/ieo iaoe, aeioeaio Ia?aoya?i Ieaa Aiaoie?eiae/,
?inoeooo i/ieo oai?ia ? oeaieiii? oa?ai?? ?i. A.I.O?eaoiaa, ea??aiee
a?aeae?eaiiy iooaeueiiaiaeie?eiieia?? ? i?e?io??o?a?/iiai e?eoaaiiy
aeaoeiie

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee ni?a?ia?oiee Naaei Aaeaioei
Aeaaeeneaaiae/, ?inoeooo i/ieo oai?ia ? oeaieiii? oa?ai??
?i.A.I.O?eaoiaa, ea??aiee a?aeae?eaiiy oaa?o?a

aeieoi? iaaee/ieo iaoe, aeioeaio Iao?oiy Aiae??e Ieoaeeiae/, Eoaainueeee
aea?aeaaiee iaaee/iee oi?aa?neoao, aeioeaio eaoaae?e i/ieo oai?ia

I?ia?aeia onoaiiaa:Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y,
eaoaae?a i/ieo oai?ia, IIC Oe?a?ie, i. Aei?i?iiao?ianuee

Caoeno a?aeaoaeaoueny “22” aeiaoiy 1999 ?. i “ 10 ” aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 41.556.01 a ?inoeooo? i/ieo
oai?ia ? oeaieiii? oa?ai?? ?i.A.I.O?eaoiaa ca aae?anith: 270061, i.
Iaeana, O?aioeocueeee aoeueaa?, 49/51.

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeoooo i/ieo
oai?ia ? oeaieiii? oa?ai?? ?i.A.I.O?eaoiaa (270061, i. Iaeana,
O?aioeocueeee aoeueaa?, 49/51).

Aaoi?aoa?ao ?ic?neaiee “ 21 ” aa?aniy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani?
A.N.Iiiiia?/oe

caaaeueia oa?aeoa?enoeea ?iaioe

Aeooaeuei?noue oaie. A oaia??oi?e /an niinoa??aa?oueny oaiaeaioe?y aei
c?inoaiiy caoai?thaaiino? ia oeoe?iaee ae?aaao (OeAe) o anueiio na?o?,
ui i?ecaiaeeoue aei ca?eueoaiiy a?aeiinii? /anoee oai?eo ia OeAe na?aae
caaaeueiiai eiioeiaaioo iooaeueiieia?/ieo iaoe??io?a, ye? no?aaeaeathoue
ia eaoa?aeoo. A?aeiii, ui eaoa?aeoa i?e OeAe cono??/a?oueny /ano?oa, a
a?eueo iieiaeiio a?oe?, ? i?ia?ano? oaeaeoa. A?ae 7% aei 19% an?o
oai?eo, ye? iia?othoueny c i?eaiaeo eaoa?aeoe, neeaaeathoue oai?? ia
OeAe (Clayman et al., 1979; Harding J.J. et al., 1993; Gabric N. et al.,
1996). Ca aeaieie Klein A.A. et al., (1995) a oa?i?i 10 ?ie?a a?ae
ii/aoeo caoai?thaaiiy OeAe o??o?a?/ia ao?o/aiiy c i?eaiaeo eaoa?aeoe
iio?aaothoue 24,9% oai?eo ia ?inoe?iiacaeaaeiee ? 8,3% oai?eo ia
?inoe?icaeaaeiee OeAe.

I?iaeaia aeioe?eueiino? i?iaaaeaiiy ?io?aieoey?ii? ei?aeoe?? i?e OeAe,
iniaeeai i?e iayaiino? ??cieo oi?i ae?aaaoe/ii? ?aoeiiiao?? (Ae?I)
caeeoa?oueny iaae??oaiith. Aeaye? aeine?aeieee ?aeiiaiaeothoue
?iieaiooaaoe ?IE i?e a?aenooiino? Ae?I (Aeuecoa? I., 1990; Aacnia?oiee
A.I.,1990; E?ea?oeueeee A.E., 1990; ?ai?iaa A.A., 1992). Na?a??iei I.I.
(1991) aaaaea? ca iiaeeeaa ?iieaiooaaoe ?IE i?e eaae?e oi?i? ae?aaaoo oa
iacia/i?e o?eaaeino? caoai?thaaiiy, o oai?eo noa?oa 50-oe ?ie?a ? i?e
a?aenooiino? iaoieia?? n?oe?aee. ?iicaii? aaoi?e aaaaeathoue
aei?aaaeaiith ?iieaioaoe?th ?IE i?e iai?ie?oa?aoeai?e Ae?I (Stark W. et
al., 1983; Straatsma A., 1983; Sebestyen J.G., 1986; Alpar S. et al.,
1987) ? iaa?oue i?e ii/aoeia?e i?ie?oa?aoeai?e Ae?I, a oiiaao
a?aenooiino? ?oaaico ?aeaeoaeee (Cunliffe I.A. et al.,1991; Noble B., et
al.,1991).

Iayai?noue noia?a/ieo iiaeyae?a uiaei aeioe?eueiino? cai?iaaaeaeaiiy
?io?aieoey?ii? ei?aeoe?? o oai?eo ia OeAe oa eaoa?aeoo coiiaeaia
oneeaaeiaiiyie, ye? niinoa??aathoueny i?ney iia?aoe??, naieie /anoeie c
yeeo ? ae?aaeaia caiaeueia ?aaeoe?y iea oa i?ia?anoaaiiy Ae?I (Krupsky
S. et al.,1991; Pollack A. et al.,1991,1992; Schatz H. et al.,1994;
Ae?icaeianueea A.N. c ni?aaao. 1994; Einoaa N.?., 1996).

I?eeiath/e aei oaaae o?aaiaoe/i?noue oe?o?a?/iiai ao?o/aiiy i?e
aeno?aeainoey?i?e aeno?aeoe?? eaoa?aeoe (AAE) c ?iieaioaoe??th
?io?aieoey?ieo e?ic (?IE), a?eueo?noue iooaeueiieia?a (Aanaeianueea
C.O.,1989; Na?a??iei I.I.,1990; Oaaei?ia N.I. c ni?aaao., 1992),
aeacothoue ia oa, ui i?e ii?ooaii? ?ioiieia?/iiai, aoii?aeueiiai,
aaiiaeeiai?/iiai noaoono iea oa i?aai?cio a oe?eiio noa? iiaeeeaei
?icaeoie aaaeeeo i?iya?a caiaeueii? ?aaeoe?? iea iaa?oue i?e
iaoneeaaeiaiiio oiae? iia?aoe??. Iniaeeaa cia/aiiy o aeieeiaii?
i?neyiia?aoe?eiiai caiaeaiiy iea ia? ii?ooaiiy aaiaoiiooaeuei?/iiai
aa?’??o (Sanders D.R et al., 1982-1984; Ferguson V.M. et al., 1992),
iaei??th ?c i?ia?aeieo i?e/ei oeueiai ? iayai?noue ae?aaaoe/ieo
i?e?iaia?iiao?e.

Ca aeaieie ?yaeo aaoi??a, ii/aoeiaee noai ?ioiieia?/ii? ?aaeoeaiino?
i?aai?cio (??I) nooo?ai aieeaa? ia ae?aaeai?noue i?iya?a caiaeueii?
?aaeoe?? iea ia iia?aoe?eio o?aaio i?e AAE c ?iieaioaoe??th ?IE o oai?eo
ia a?eiao eaoa?aeoo (Aai?a??a Ae.N., 1983; Iaioaea?a A.A., 1996;
Aanaeianueea C.O., 1989).

A ?iaioao Aeaaoy?aiei O.A. c ni?aaao. (1981;1982;1994), Eaoeioeaai? E.O
c ni?aaao. (1981;1982;1983), Naeaeaia E.?. (1989), Aia?ii? ?.O.(1995),
Caeoeaai? I.N. c ni?aaao., (1997) Aeaa?aeoa A.O., (1997), a oaeiae
?iicaiieo aaoi??a (Esser P., 1993; Tang S., 1995; Rodriguez-Segade S.,
1996) aeeeaaeaii oa?aeoa? ?ioiieia?/ieo ii?ooaiue o oai?eo ia OeAe c
??cieie oi?iaie Ae?I, anoaiiaeaii aeai?an?th ee?oeiii? oa aeoeaaoe?th
aoii?aeueii? eaiie ?ioiii? a?aeiia?ae?, a oaeiae aooinainea?e?caoe?th
aei aioeaai?a (AA) oeaiei iea.

Ooieoe?iiaeuei? ?acoeueoaoe iia?aoeaiiai e?eoaaiiy eaoa?aeoe ?
iniaeeaino? ia?aa?ao i?neyiia?aoe?eiiai ia??iaeo i?e AAE c
?iieaioaoe??th ?IE o oai?eo, ye? no?aaeaeathoue ia ??ci? oeie OeAe
aea/aii iaaeinoaoiuei, a oaeiae ia aeine?aeaeaii oa?aeoa? ii?ooaiue
?ioiieia?/iiai noaoono i?aai?cio o oai?eo ia OeAe, ye? iio?aaothoue
aeno?aeoe?? eaoa?aeoe.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie. ?iaioa aeeiiaia
a?aeiia?aeii aei ieaio IAe? ?inoeoooo i/ieo oai?ia ? oeaieiii? oa?ai??
?i. A.I.O?eaoiaa o ?aieao aaeocaai? iaoeiai-oaoi?/ii? i?ia?aie, ? yaey?
niaith o?aaiaio oaie IAe? A01002987? “Aecia/eoe oaeoi?e ?eceeo ?icaeoeo
ae?aaaoe/ii? ?aoeiiiao??, ?ic?iaeoe nenoaio ?aiiuei? ae?aaiinoeee ia
aeiee?i?/i?e noaae??, oaeineiiaeeoe iaoiaee e?eoaaiiy”.

Iaoa aeine?aeaeaiiy. Iaoith aeine?aeaeaiiy noaei i?aeaeuaiiy
aoaeoeaiino? iia?aoe?? AAE c ?iieaioaoe??th ?IE o oai?eo ia oeoe?iaee
ae?aaao ia i?aenoaa? aea/aiiy iniaeeainoae ia?aa?ao i?neyiia?aoe?eiiai
ia??iaeo, noaio ?ioiieia?/ii? ?aaeoeaiino? o oeeo oai?eo oa ?ic?iaee
ee?i?ei-?ioiieia?/ieo e?eoa???a i?iaiicoaaiiy ?icaeoeo i?neyiia?aoe?eieo
oneeaaeiaiue caiaeueiiai oa?aeoa?o, ye? aieeaathoue ia ooieoe?iiaeuei?
iane?aeee iia?aoe??.

Caaea/? aeine?aeaeaiiy:

1. Aea/eoe iniaeeaino? ee?i?/iiai ia?aa?ao i?neyiia?aoe?eiiai ia??iaeo
i?e AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe I ? II oeio oa i?iaanoe
aiae?c ooieoe?iiaeueieo ?acoeueoao?a cai?iaaaeaeaiiai iia?aoeaiiai
ao?o/aiiy.

2. Aea/eoe ii/aoeiaee noai oa aeeiai?eo ?ioiieia?/ii? ?aaeoeaiino?
i?aai?cio o oai?eo ia OeAe I ? II oeio oa eaoa?aeoo ? aecia/eoe cia/aiiy
ii?ooaiue ?ioiieia?/iiai noaoono o oai?eo ia OeAe o aeieeiaii? ?
?icaeoeo i?neyiia?aoe?eii? caiaeueii? ?aaeoe?? iea i?e AAE c
?iieaioaoe??th ?IE.

3.Aecia/eoe oaeoi?e ?eceeo ?icaeoeo aaaeei? caiaeueii? ?aaeoe?? iea
i?ney AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe ia i?aenoaa?
ia?aaeiia?aoe?eieo ee?i?ei-?ioiieia?/ieo aeaieo.

4.Aea/eoe aoaeoeai?noue AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe, yeo
aoei i?iaaaeaii ?c a?aooaaiiyi oaeoi??a ?eceeo ?icaeoeo aaaeei?
i?neyiia?aoe?eii? caiaeueii? ?aaeoe??.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa anoaiiaeaii iniaeeaino?
ii?ooaiiy ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio o oai?eo ia eaoa?aeoo ?
OeAe — i?eai?/aiiy ooieoe?iiaeueii? aeoeaiino? O-noi?ani?ii? eaiee
ee?oeiiiai ?ioieoaoo ? aenieee ??aaiue nainea?e?caoe?? aei aioeaai?a
noaeeiii? iaieiiee oa e?eooaeeea, a?eueo ae?aaeai? i?e ?inoe?icaeaaeiiio
oei? caoai?thaaiiy, iieacaii cia/aiiy aeyaeaieo ii?ooaiue ?ioiieia?/iiai
noaoono oai?eo ia OeAe o aeieeiaii? oa ?icaeoeo i?neyiia?aoe?eii?
caiaeueii? ?aaeoe?? iea i?e AAE c ?iieaioaoe??th ?IE.

Anoaiiaeaii, ui oaeoi?aie ?eceeo aeey ?icaeoeo neeueii?
i?neyiia?aoe?eii? caiaieueii? ?aaeoe?? i?e AAE c ?iieaioaoe??th ?IE o
oai?eo ia OeAe ? OeAe aaaeeiai nooiaiy, iayai?noue i?ioa?io???, aenieee
??aaiue oeoe?o a e?ia? oa cia/aiiy ?ioii?aaoeyoi?iiai ?iaeaeno.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Anoaiiaeaii, ui i?e AAE c
?iieaioaoe??th ?IE ia?aa?a i?neyiia?aoe?eiiai ia??iaeo a?eueo aaaeeee o
oai?eo ia oeoe?iaee ae?aaao, i?ae o oai?eo ia a?eiao eaoa?aeoo.
I?neyiia?aoe?eia caiaeueia ?aaeoe?y neeueiiai nooiaiy niinoa??aaeinue o
oai?eo ia OeAe I ? II oeio a 3-5 ?ac?a /ano?oa, i?ae o oai?eo ia a?eiao
eaoa?aeoo.

A?aooaaiiy aeyaeaieo oaeoi??a i?iaiicoaaiiy caiaeueieo oneeaaeiaiue o
ia?aaeiia?aoe?ei?e i?aeaioiaoe? oai?eo aeicaieeei i?aeaeueoe
ooieoe?iiaeueio aoaeoeai?noue (aino?ioa ci?o 0,5 ? aeua) AAE c
?iieaioaoe??th ?IE ia 16,8%.

Ai?iaaaeaeaiiy ?acoeueoao?a ?iaioe a i?aeoe/io iooaeueiieia?th aoaea
ni?eyoe iie?ioaiith ooieoe?iiaeueieo iane?aee?a oa ee?i?/ii?
aoaeoeaiino? iia?aoe?? AAE c ?iieaioaoe??th ?IE o oai?eo ia oeoe?iaee
ae?aaao.

Ai?iaaaeaeaiiy a i?aeoeeo. ?ic?iaeaii niin?a i?iaiicoaaiiy neeueii?
i?neyiia?aoe?eii? caiaeueii? ?aaeoe?? i?e aeno?aeainoey?i?e aeno?aeoe??
eaoa?aeoe c ?iieaioaoe??th ?IE o oai?eo ia oeoe?iaee ae?aaao ia
i?aenoaa? ioe?iee iieaciee?a ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio.

?acoeueoaoe aeine?aeaeaiue ai?iaaaeaeai? a ee?i?/io i?aeoeeo ?
canoiniaothoueny ia aac? a?aeae?eaiiy iooaeueiiaiaeie?eiieia?? ?
i?e?io??o?a?/iiai e?eoaaiiy aeaoeiie Iinoeoooo i/ieo oai?ia ? oeaieiii?
oa?ai?? ?i. A.I.O?eaoiaa.

Iniiai? iaoeia? ? i?aeoe/i? iieiaeaiiy ?iaioe aeeth/aie a i?ia?aio
eaeoe?e ? i?aeoe/ieo caiyoue ia?aaeaoanoaoe?eieo oeeee?a eaoaae?e
iooaeueiieia?? c ?aae?aoe?eiith iaaeeoeeiith oaeoeueoaoo i?neyaeeieiiii?
i?aeaioiaee e?ea??a Iaeanueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.

Iniaenoee aianie caeiaoaa/a: Ianoaaeaiiy oa e?eoaaiiy oai?eo ia
eaoa?aeoo ? OeAe, a oaeiae ia a?eiao eaoa?aeoo i?iaaaeaii o a?aeae?eaii?
iooaeueiiaiaeie?eiieia?? ? i?e?io??o?a?/iiai e?eoaaiiy aeaoeiie
?inoeoooo i/ieo oai?ia ? oeaieiii? oa?ai?? ?i. A.I.O?eaoiaa ca o/anoth
ea??aieea a?aeae?eaiiy aeioe., e.i.i. Ia?aoya?ia I.A.

?ioiieia?/ia ianoaaeaiiy oai?eo i?iaaaeaii a eaai?aoi??? ?ioiieia?? ?
iaoiii?oieia?? oeaiei ?inoeoooo i/ieo oai?ia ? oeaieiii? oa?ai?? ?i.
A.I.O?eaoiaa ca o/anoth no. iaoe. ni?a?., ae.i.i. Aeaaoy?aiei O.A.

Naiino?eii caeiaoaa/ai i?iaaaeaii iooaeueiieia?/ia ianoaaeaiiy, aiae?c
io?eiaieo ee?i?/ieo ?acoeueoao?a o iaoe??io?a, aiae?c ?acoeueoao?a
?ioiieia?/ieo aeine?aeaeaiue, a oaeiae ?o eiii’thoa?iee noaoenoe/iee
aiae?c.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee ?iaioe aeeeaaeai? ?
iaaiai?ai? ia can?aeaii? Iaeanueeiai iaeaniiai iaoeiaiai oiaa?enoaa
iooaeueiieia?a (1998 ?. i. Iaeana) oa Iaoeia?e eiioa?aioe??
iooaeueiieia?a, i?enay/ai?e 90-??//th aeaae. I.I.Io/eianueei? (1998 ?.,
i. Iaeana).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 5 ?ia?o, c ieo 3 noaoo?
o oaoiaeo iaoeiaeo aeo?iaeao, 1 noaooy — o oaoiaiio ca??ieeo iaoeiaeo
i?aoeue, 1 — o oacao iaoeiai? eiioa?aioe?? iooaeueiieia?a.

No?oeoo?a oa ianya aeena?oaoe??. Aeena?oaoe?y iaienaia ?in?enueeith
iiaith, aeeeaaeaia ia 148 noi??ieao eiii’thoa?iiai oaenoo. Neeaaea?oueny
?c anooio, 5 ?icae?e?a, caeeth/aiiy, aeniiae?a oa nieneo aeei?enoaii?
e?oa?aoo?e. Aeena?oaoe?y ?ethno?iaaia 4 ae?aa?aiaie, 29 oaaeeoeyie, 11
oioia?ao?yie, 4 aeieneaie c ?noi??e oai?ia, ye? caeiathoue 11 noi??iee.
Nienie aeei?enoaii? e?oa?aoo?e i?noeoue 217 iaeiaioaaiue ? ?ici?uo?oueny
ia 24 noi??ieao.

INIIAIEE Ci?no ?iaioe

Ia’?eo oa iaoiaee aeine?aeaeaiiy. I?aaenoaaeai? iooaeueiieia?/i? oa
ee?i?ei-?ioiieia?/i? aeine?aeaeaiiy i?iaiaeeeenue ia aac? a?aeae?eaiiy
i?e?io??o?a?? aeaoeii oa iooaeueiiaiaeie?eiieia?? ? eaai?aoi???
?ioiieia?? oa iaoiii?oieia?? oeaiei ?inoeoooo i/ieo oai?ia ? oeaieiii?
oa?ai?? ?i. A.I.O?eaoiaa ia i?ioyc? 1996-1998 ??. I?ae niinoa?aaeaiiyi
ia?aaoaaei 215 oai?eo ia eaoa?aeoo (239 i/ae), c yeeo 11 oai?eo OeAe I
oeio (16 i/ae) ? 128 oai?eo OeAe II oeio (147 i/ae). An?i oai?ei aoea
i?iaaaeaia AAE c ?iieaioaoe??th caaeiueieaia?ii? ?IE (iiaeae? J-loop, c
oe?eueiiai iie?iaoeeiaoae??eaoa) c o?enaoe??th a oeee?a?i?e ai?ici?.

Na?aaei?e a?e oai?eo nooo?ai a?ae??ciyany o aeuacacia/aieo a?oiao oai?eo
ia OeAe: 21,5±1,2 ??e o oai?eo ia ?inoe?icaeaaeiee ae?aaao; 63,1±0,9
?ie?a o oai?eo ia ?inoe?iiacaeaaeiee ae?aaao, a?i neeaaeaa 70,1±1,0
?ie?a o eiio?ieuei?e a?oi?. Na?aaei?e oa?i?i a?ae aecia/aiiy ae?aaaoo
aei iia?aoeaiiai ao?o/aiiy o oai?eo ia OeAe I oeio neeaa 10,6±1,0 ?ie?a,
a o oai?eo ia OeAe II oeio 12,5±0,7 ?ie?a. Eiiiainaoe?y oeoe?iaiai
ae?aaaoo cae?enithaaeanue o 39 oai?eo ca aeiiiiiaith ?inoe?iioa?ai??, o
78 oai?eo ia?i?aeueieie oeoe?icieaeoth/eie i?aia?aoaie, ? o 22 oai?eo
aeio?eiaiiyi ae??oe.

Iooaeueiieia?/i? iaoiaee aeine?aeaeaiiy aeeth/aee: 1) aecia/aiiy
aino?ioe ci?o ca aeiiiiiaith oaaeeoe? A.Oaaaeueiaa aai niaoe?aeueieie
iioioeiaie; 2) a?ii?e?ineii?th ia?aaeiueiai a?aeae?eo i/iiai yaeoea ia
u?eeii?e eaii? o??ie Opton, (I?ia//eia) ca?aeii aei caaaeueiii?eeiyoi?
iaoiaeeee; 3) aii?ineii?th (ca aeiiiiiaith o?ueioaeca?eaeueii? e?ice
Aieueaeiaiia); 4) i?yio iooaeueiineii?th aeaeo?iiooaeueiineiiii o??ie
Carl Zeiss Jena (I?ia//eia) ? cai?ioith iooaeueiineii?th ca aeiiiiiaith
a?iieoey?iiai iooaeueiineiia IAI-3; 5) oiiiiao??th ca iaoiaeii Iaeeaeiaa
aaioaaeai 10 a.; 6) ioe?iea noaio caaeiueiai a?aeae?eo i/iiai yaeoea i?e
ae?aaeaieo iiiooi?iiyo iioe/ieo na?aaeiaeu i?iaiaeeeanue ca aeiiiiiaith
oeueo?acaoeiaeo aeine?aeaeaiue (A ? A — iaoiaee neaioaaiiy); 7)
ooieoe?iiaeuei? aeaeo?io?c?ieia?/i? aeine?aeaeaiiy noaio ci?iaiai
aiae?caoi?a (IA*O — ii??a aeaeo?e/ii? /ooeeaino? ci?iaiai aiae?caoi?a ca
oinoaiii — ii?ia 30-70 ieA, eaa?euei?noue (e?eoe/ia /anoioa cieeiaiiy
ieaio?iue, E*CIO, ii?ia 40-60 Aoe)) — ia noeioeyoi?? iooaeueiieia?/iiio
EINI-2 “Oinoai”; 8) aeine?aeaeaiiy iiey ci?o ia i?iaeoe?eiiio ia?eiao??
o??ie Carl Zeiss Jena (I?ia//eia).

?ioiieia?/ia ianoaaeaiiy oai?eo i?iaiaeeeinue ca 1-2 aei? aei iia?aoe??
? ia 7-10 aeiao i?ney iia?aoeaiiai ao?o/aiiy. Aiii aeeth/aei aea/aiiy
noaio O-? A- nenoai ?ioi?oaoo, ianiaoeeo?/iiai ?ioi?oaoo, a oaeiae
ioe?ieo nainea?e?caoe?? i?aai?cio aei aioeaai?a oeaiei iea. ?ioiieia?/i?
aeine?aeaeaiiy cae?enithaaeenue ca iaoiaee/ieie ?aeiiaiaeaoe?yie
“Onei?aiiay ia?ae/iay ioeaiea eiioiiiai noaoona /aeiaaea”, ye? aoee
?ic?iaeai? a ?inoeooo? i/ieo oai?ia ? oeaieiii? oa?ai?? ?iai? A.I.
O?eaoiaa (1990) a oaeiae ?c canoinoaaiiyi iaoiaeeee ioe?iee
nainea?e?caoe?? i?aai?cio aei AA oeaiei iea (Aeaaoy?aiei O.A., 1992).

Aeey ioe?iee noaio ee?oeiiiai ?ioieoaoo i?iaiaeeee: 1) aecia/aiiy
aaniethoiiai ai?noo eaeeioeeo?a oa e?ioioeeo?a o e?ia?; 2) aecia/aiiy
a?aeiinii? oa aaniethoii? e?eueeino? O-e?ioioeeo?a ca oanoii niiioaiiiai
?icaoeiooai?aiiy c a?eo?ioeeoaie aa?aia (A-?OE); 3) ioe?ieo
ooieoe?iiaeueii? aeoeaiino? noaiiioeyoe?e O-e?ioioeeo?a, ye? iathoue
oaeia?i? oa noi?ani?i? aeanoeaino? ca aeaieie iaaaioaaeoaaeueiiai oanoa
A — ?icaoeiooai?aiiy e?ioioeeo?a i?ney ?o ?ieoaaoe?? c oaio?e?iii.

Aeey aea/aiiy noaio aoii?aeueiiai ?ioi?oaoo canoiniaoaaee: 1) aecia/aiiy
a?aeiinii? oa aaniethoii? e?eueeino? A-e?ioioeeo?a ca oanoii
?icaoeiooai?aiiy c a?eo?ioeeoaie ieo? (I-?OE); 2) aecia/aiiy ai?noo
?ioiiaeiaoe?i?a A, G ? I eean?a o ieaci? e?ia? iaoiaeii ?aae?aeueii?
?ioiiaeeooc?? ca Iai/?i?.

Aeey ioe?iee noaio ianiaoeeo?/iiai ?ioi?oaoo aecia/aee: 1) oaaioeeoa?io
aeoeai?noue iaeo?io?e?a c ee?oeiaie iaea?nueeeo ae??aeaeae?a, o?eniaaieo
iaa??aaiiyi; 2) ooieoe?iiaeueio aeoeai?noue iaeo?io?e?a ca oanoii I-?OE,
?ic?aoiaoaaee oaeiae ?iaeaen iaaaioaaeaiiy (A-?IE/A-?II).

Nainea?e?caoe?y i?aai?cio aei aooiaioeaai?a ioe?ithaaeanue ca
iaaaioaaeoaaeueieie oanoaie A-?OE c aooiaioeaaiaie noaeeiii? iaieiiee
iea oa e?eooaeeea.

Nooi?iue i?iya?a caiaeueii? ?aaeoe?? a ?aiiueiio i?neyiia?aoe?eiiio
ia??iae? i?ney AAE c ?iieaioaoe??th ?IE aecia/aany ca?aeii eeaneo?eaoe??
Na?a??iea I.I.- Aanaeianueei? C.O. (1985), ca yeith a IC? aeae?eythoueny
o?e nooiai? aaaeeino?: I — neaaeee, II — na?aaei?e oa III — neeueiee. O
oai?eo ??cieo a?oii, ui ciaoiaeeeeny i?ae iaoei niinoa?aaeaiiyi,
e?eoaaiiy o i?neyiia?aoe?eiiio ia??iae? aoei aiaeia?/iei aei
o?aaeeoe?eiiai oa, ca?aeii aei ?aeiiaiaeaoe?e aeuacaaaeaieo aaoi??a,
aeeth/aei aioea?ioeee, noa?i?aei? ? ianoa?i?aei? i?ioecaiaeuei? caniae,
o?a?eiie?cei ? o.ae.

Aeey aea/aiiy a?aeaeaeaieo ?acoeueoao?a oai?? aoee ianoaaeai? a ??ci?
oa?i?ie (1, 3, 6 ? 12 i?n.) i?ney iia?aoeaiiai ao?o/aiiy.

Noaoenoe/ia ia?iaea aeaieo i?iaiaeeeanue ca aeiiiiiaith i?ia?aie
STATISTICA for Windows (Ai?iaeeia A.I. 1997) ia ia?niiaeueiiio
eiii’thoa?? ia aac? i?ioeanni?a ?entium 166 IIO. Io?eiai? ii??aiyeuei?
oa ei?aeyoe?ei? iieacieee i?eeiaeeny ca a??ia?aei? i?e aaee/ei?
eiao?oe??ioo a??ia?aeiino? ? < 0,05. Ee?i?/i? ?acoeueoaoe aeno?aeainoey?ii? aeno?aeoe?? eaoa?aeoe c ?iieaioaoe??th ?IE o oai?eo ia oeoe?ia?e ae?aaao. Aeey aea/aiiy iniaeeainoae ee?i?/iiai ia?aa?ao i?neyiia?aoe?eiiai ia??iaeo i?e AAE c ?iieaioaoe??th ?IE ? ?o cia/aiiy aeey ooieoe?iiaeueieo ?acoeueoao?a iia?aoe?? i?iaaaeaii aiae?c ?acoeueoao?a caaaeueiiee?i?/ieo oa iooaeueiieia?/ieo aeine?aeaeaiue o 177 oai?eo (101 oai?ee ia OeAe oa eaoa?aeoo ? 76 oai?eo ia a?eiao eaoa?aeoo aac OeAe), yeei aoea cae?eniaia AAE c ?iieaioaoe??th caaeiueieaia?ii? ?IE (194 i/ae). Ianoaaeaiiy o a?aeaeaeai? no?iee -1 ??e ? a?eueoa - i?iaaaeaii o 89 oai?eo ia OeAe oa eaoa?aeoo (106 i/ae) ? o 73 oai?eo ia a?eiao eaoa?aeoo (73 i/ae). Ca?aeii aei caaea/ aeine?aeaeaiiy oai?? aoee ?iciiae?eai? ia 3 a?oie. Ia?oo a?oio neeaaeaee 11 oai?eo ia OeAe I oeio (16 i/ae), ae?oao a?oio - 90 oai?eo ia OeAe II oeio (102 i/ae). O?aoth, eiio?ieueio a?oio neeaaeaee 75 oai?eo ia a?eiao eaoa?aeoo (76 i/ae). Ee?i?/iee aiae?c i?iya?a caiaeueii? ?aaeoe?? iea i?ney AAE c ?iieaioaoe??th ?IE i?iaiaeeany ca?aeii eeaneo?eaoe?? Na?a??iea I.I. ? Aanaeianueei? C.O. (1985). Iooaeueiieia?/i? ianoaaeaiiy iieacaee, ui ia?aa?a i?neyiia?aoe?eiiai ia??iaeo aoa iaea?eueo iani?eyoeeaei o oai?eo ia OeAe I oeio (oaae.1). O oeeo iaoe??io?a i?neyiia?aoe?eia caiaeueia ?aaeoe?y (IC?) iea neeueiiai ? na?aaeiueiai nooiaiy cono??/aeenue o 37,5% ? 50,0% aeiaaee?a, a neaaea ?aaeoe?y - anueiai o 12,5% aeiaaee?a. O oai?eo ia OeAe II oeio caiaeueia ?aaeoe?y neaaeiai nooiaiy niinoa??aaeanue o 39% aeiaaee?a, a IC? na?aaeiueiai ? neeueiiai nooiaiy - a?aeiia?aeii a 39% ? 22% aeiaaee?a. O oai?eo ia a?eiao eaoa?aeoo (eiio?ieueia a?oia) niinoa??aaany iaea?eueo ni?eyoeeaee ia?aa?a i?neyiia?aoe?eiiai ia??iaeo. A oe?e a?oi? o a?eueoino? oai?eo niinoa??aaany neaaeee nooi?iue i?iyao IC? iea (65%), a IC? na?aaeiueiai ? neeueiiai nooiaiy aecia/aeenue o 28% ? 8% aeiaaee?a, a?aeiia?aeii. A?aei?iiino? a nooiaiyo aaaeeino? IC? iea i?ae ianoaaeaieie a?oiaie oai?eo ia OeAe ? ia a?eiao eaoa?aeoo aoee a??ia?aeieie (P<0,05). Oaaeeoey 1 Nooi?iue aaaeeino? i?neyiia?aoe?eiiai caiaeaiiy i?ney AAE c ?iieaioaoe??th ?IE o oai?eo, ui ciaoiaeeeeny i?ae niinoa?aaeaiiyi Nooi?iue IC?Oai?? ia OeAe I oeioOai?? ia OeAe II oeioEiio?ieueia a?oiaI - neaaeee2 (12,5%)40 (39,2%)49(64,5%)II - na?aaei?e8 (50,0%)40 (39,2%)21 (27,6%)III - neeueiee6 (37,5%)22 (21,6%)6 (7,9%)Anueiai i/ae: 1610276 Ioe?iea ooieoe?iiaeueieo ?acoeueoao?a ai?iaaaeaeaiiai e?eoaaiiy i?e AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe a ?aiiueiio i?neyiia?aoe?eiiio ia??iae? (/a?ac 2 oeaei? i?ney iia?aoe??), iieacaea, ui iieacieee aino?ioe ci?o a oe?e a?oi? aoee ieae/eie o ii??aiyii? c oai?eie eiio?ieueii? a?oie. Iniiaiith i?e/eiith oeueiai aoee i?iyae i?neyiia?aoe?eii? caiaeueii? ?aaeoe?? iea o aeaeyae? ea?aoiiao??, aenoaeaoe?? a ia?aaeith eaia?o, caeeoe?a o?a?eiii? ie?aee ia ?IE, a oaeiae o /anoeie oai?eo - aiane?aeie iayaiino? ae?aaaoe/ieo ci?i n?oe?aee. sse iieacaee iiaeaeueo? niinoa?aaeaiiy ca ci?iaeie ooieoe?yie, aino?ioa ci?o iie?ioeeanue o a?eueoino? oai?eo an?o a?oi (oaae.2). Oaaeeoey 2 A?aeaeaeai? ooieoe?iiaeuei? ?acoeueoaoe i?ney AAE c ?iieaioaoe??th ?IE Aino?ioa ci?oOai?? ia OeAe I oeio Oai?? ia OeAe II oeio Eiio?ieueia a?oia (oai?? ia a?eiao eaoa?aeoo)0,01-0,10 (0%)11 (12,2%)1 (1,4%)0,12-0,43 (18,8%)18 (20,0%)8 (10,9%)>0,513 (81,2%)61 (67,8%)64
(87,7%)Anueiai i/ae:169073

Oae, /a?ac 1 ??e i?ney iia?aoe?? AAE c ?iieaioaoe??th ?IE aino?ioa ci?o
0,5 e aeua niinoa??aaeanue o 81,2% oai?eo ia OeAe I oeio ? o 67,8%
oai?eo ia OeAe II oeio (a eiio?ieuei?e a?oi? oaeo aino?ioo ci?o
a?aecia/aii a 87,7% aeiaaee?a). Aino?ioa ci?o 0,5 e aeua a oe?eiio a
ianoaaeaieo oai?eo ia OeAe niinoa??aaeinue ia 74-o c 106 i/ae, ui neeaei
69,8% aeiaaee?a.

Iaiao?aeii a?aecia/eoe, ui i?e iayaiino? Ae?I aino?ioa ci?o 0,5 ? aeua
niinoa??aaeanue o?eueee o 50,0% oai?eo, a i?e iayaiino? ae?aaaoe/iiai
o?aaeaiiy iaeoey?ii? iaeano? oaeeo ooieoe?iiaeueieo ?acoeueoao?a
e?eoaaiiy aoei aeinyaiooi eeoa a 11,5% aeiaaee?a.

?ao?iniaeoeai? niinoa?aaeaiiy aeicaieeee anoaiiaeoe, ui o oai?eo ia
OeAe, yeei aoei cae?eniaii AAE c ?iieaioaoe??th ?IE, /a?ac 1 ??e i?ney
iia?aoeaiiai ao?o/aiiy aeineoue aenie? ooieoe?iiaeuei? ?acoeueoaoe aoei
io?eiaii i?e neaaeiio oa na?aaeiueiio nooiaiyo i?iya?a IC? iea a
?aiiueiio i?neyiia?aoe?eiiio ia??iae?. I?e oeueiio aino?ioa ci?o 0,5 ?
aeua niinoa??aaeanue a?aeiia?aeii a 32 (80,0%) ? 33 (75,0%) aeiaaee?a. A
o oai?eo c neeueiith caiaeueiith ?aaeoe??th iea i?ney AAE c
?iieaioaoe??th ?IE aeniea aino?ioa ci?o (0,5 ? aeua) niinoa??aaeanue
o?eueee o 9 aeiaaeeao ?c 22, ui neeaaeaei 40,9%. I?e oeueiio a 4
aeiaaeeao (18,2%) aino?ioa ci?o o iaoe??io?a aoea ieaea 0,1.

A eiio?ieuei?e a?oi? oai?eo ia a?eiao eaoa?aeoo noa?a/a iaeoeiaeeno?io?y
aoea aieiaiith i?e/eiith iecueei? aino?ioe ci?o o a?aeaeaeai? no?iee
i?ney AAE c ?iieaioaoe??th ?IE.

Iaeiei c iae/ano?oeo oneeaaeiaiue o a?aeaeaeaiiio i?neyiia?aoe?eiiio
ia??iae? i?e AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe aoea aoi?eiia
eaoa?aeoa. *anoioa aoi?eiii? eaoa?aeoe o oai?eo ia OeAe (30,2%) a
oe?eiio aoea aeuith, i?ae o eiio?ieuei?e a?oi? (21,9%; c2=4,16; P<0,05). I?ia?anoaaiiy Ae?I ia i?ioyc? iaeiiai ?ieo i?ney iia?aoeaiiai ao?o/aiiy a?aei?/aii o 9 aeiaaeeao (8,4%). Ia 21 ioe? aoei i?iaaaeaii eaca?eiaaoeyoe?th n?oe?aee c i?eaiaeo Ae?I. Iayai?noue ?IE ia aoea ia?aoeiaeith aeey i?iaaaeaiiy eaca?eiaaoeyoe?? i?e i?ino?e Ae?I, eeoa a iaeiiio aeiaaeeo iai?aoeiaeueia eaca?eiaaoeyoe?y aoea oaoi?/ii oneeaaeiaia /a?ac iaaeinoaoi? ?icoe?aiiy c?ieoe? aiane?aeie iayaiino? caaei?o n?iao?e. Ee?i?/i? niinoa?aaeaiiy iieacaee, ui neeueiee nooi?iue caiaeueii? ?aaeoe?? iea a i?neyiia?aoe?eiiio ia??iae? i?ecaiaeeoue aei ooai?aiiy no?eeeo caaei?o n?iao?e, aeaoi?iaoe?e c?ieoe?, a oaeiae cia/ii iia??oo? oiiae aeey iiaeaeueoiai iooaeueiieia?/iiai niinoa?aaeaiiy ca oai?eie ia OeAe. Aeey aecia/aiiy oaeoi??a ?eceeo uiaei ?icaeoeo neeueii? caiaeueii? ?aaeoe?? iea, oai?? ia OeAe, yeei aoei cae?eniaii AAE c ?iieaioaoe??th ?IE, aoee ?iciiae?eai? ia aea? a?oie. Ia?oo a?oio neeaaeaee oai?? c ni?eyoeeaei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo (iaoe??ioe c I ? II nooiaiyie i?iyao IC? iea). Ae?oao a?oio c iani?eyoeeaei (oneeaaeiaiei) ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo neeaee oai?? n III nooiaiai i?iyao IC? iea. A?aoiaoth/e ??cieoeth a ao?ieia??, iaoio?c?ieia?? oa ee?i?/ieo i?iyaao, aeey eiaeiiai oeio OeAe aiae?c i?iaiaeeany ie?aii. Aoei i?iaaaeaii ei?aeyoe?eiee aiae?c i?ae aaaee?noth IC? ? o?eaae?noth caoai?thaaiiy OeAe, aaaee?noth OeAe, a?eii oai?eo, iayai?noth ?aoeiiiao??, ??aiai oeoe?o a e?ia? oai?eo aei iia?aoe??, oaeaee?noth in?aeaiiy a?eo?ioeeo?a, iayai?noth i?ioa?io???. O oai?eo ia OeAe II oeio ??aaiue oeoe?o a e?ia? o a?oi? c oneeaaeiaiei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo aoa aeuei, i?ae o a?oi? c iani?eyoeeaei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo (10,4±1,13 e 7,8±0,30 iiieue/e, o 1-e e 2-e a?oiao a?aeiia?aeii; P<0,05). I?iaaaeaiee ii??aiyeueiee aiae?c aeicaieea anoaiiaeoe a??ia?aeio ??cieoeth a?aeiinii /anoioe neeueii? IC? iea i?e AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe II oeio i?e ??ai? oeoe?o a e?ia? ieae/a 10,0 iiieue/e ? o oai?eo ia OeAe II oeio c ??aiai oeoe?o a e?ia? aeua ca 10,0 iiieue/e (c2=4,24; P<0,05). Iaiao?aeii aeacaoe ia ??cieoeth o /anoio? aeyaeaiiy neeueii? IC? iea i?ney AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe II oeio caeaaeii a?ae iayaiino? i?ioa?io???. Oae, /anoioa niinoa?aaeaiiy neeueii? IC? iea i?ney iia?aoe?? AAE c ?iieaioaoe??th ?IE i?e iayaiino? i?ioa?io??? aei??aithaaea 7 aeiaaeeai ?c 13 (53,8%), i?e ?? a?aenooiino? - 16 aeiaaeeai ?c 89 (18,0%). Aeuacacia/aia ??cieoey aoea noaoenoe/ii a??ia?aeiith (c2=6,43; ?<0,05), ui ia? na?ae/eoe i?i i?aeaeuaiee ?ecee ?icaeoeo IC? neeueiiai nooiaiy o oai?eo ia OeAe II oeio c i?ioa?io???th. Ne?ae cacia/eoe, ui o oai?eo ia OeAe II oeio neeueia IC? iea i?ney AAE c ?iieaioaoe??th ?IE iaaaaaoi /ano?oa niinoa??aaeanue i?e aaaeeiio ia?aa?ao OeAe, a naia o 4-o aeiaaeeao c 6, (66,7%), a oie /an, ye i?e OeAe eaaeiai e na?aaeiueiai nooiai?a aaaeeino? - o?eueee o 18-oe aeiaaeeao c 96 (18,8%). I?iaaaeaiee ii??aiyeueiee aiae?c iieacaa aenieo a??ia?aei?noue aeuacacia/aii? ??cieoe? (c2=4,91; P<0,01). I?e aeacaieo oiiaao aoea aeyaeaia oaeiae noaoenoe/ii iacia/ia oaiaeaioe?y aei a?eueoi? /anoioe neeueii? IC? o oai?eo ia OeAe I oeio. A??ia?aeii? ei?aeyoe?? i?ae /anoioith niinoa?aaeaiiy IC? iea neeueiiai nooiaiy o oai?eo ia OeAe i?e AAE c ?iieaioaoe??th ?IE oa a?eii, noaooth oai?eo, o?eaae?noth caoai?thaaiiy ae?aaaoii, ??aiai oaeaeeino? in?aeaiiy a?eo?ioeeo?a, a oaeiae iayai?noth Ae?I anoaiiaeaii ia aoei. Oaeei /eiii, ii??aiyeueiee aiae?c i?iaaaeaieo iooaeueiieia?/ieo oa ee?i?ei - eaai?aoi?ieo aeine?aeaeaiue o oai?eo ia OeAe II oeio, yeei aoei cae?eniaii iia?aoe?th AAE c ?iieaioaoe??th ?IE aeicaieea ocaaaeueieoe, ui nooo?aeie oaeoi?aie ?eceeo aeey ?icaeoeo neeueii? IC? iea a i?neyiia?aoe?eiiio ia??iae? ? oae?: aaaeeee ia?aa?a OeAe, iayai?noue i?ioa?io??? oa a?ia?ae?eai?y aeua 10,0 iiieue/e. Noai ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio o oai?eo ia oeoe?iaee ae?aaao i?e aeno?aeainoey?i?e aeno?aeoe?? eaoa?aeoe c ?iieaioaoe??th ?io?aieoey?ieo e?ic. O 11 oai?eo ia OeAe I oeio ? 45 oai?eo ia OeAe II, yeei aoei aeeiiaii AAE c ?iieaioaoe??th ?IE i?iaiaeeeinue ?ioiieia?/ia ianoaaeaiiy aei ? i?ney iia?aoeaiiai ao?o/aiiy. Eiio?ieueio a?oio neeaee 40 oai?eo ia a?eiao eaoa?aeoo. Ca iieacieee ii?ie aoee i?eeiyo? aeai? ?ioiieia?/iiai ianoaaeaiiy 70 caei?iaeo aeiii??a a?eii 30-70 ?ie?a. Aiae?c iieaciee?a ee?oeiiiai ?ioi?oaoo o oai?eo ia eaoa?aeoo oa OeAe I oeio aei iia?aoe?? aeyaea a??ia?aeia ?o cieaeaiiy a ii??aiyii? c oai?eie ia OeAe II oeio ? c oai?eie, ye? no?aaeaeaee eeoa ia a?eiao eaoa?aeoo. E?euee?noue O-e?ioioeeo?a o ia?eoa??ei?e e?ia? oai?eo ia OeAe I oeio neeaea 1054±52 ee/iee (a??ia?aei?noue ??cieoe? c ii?iith P<0,05), o oai?eo ia OeAe II oeio aiia aei??aithaaea 1265±79 ee/iee (P>0,05). O
eiio?ieuei?e a?oi? oai?eo ia a?eiao eaoa?aeoo e?euee?noue O-e?ioioeeo?a
aoea a iaaeao ii?ie ? neeaaeaea 1300±107 ee/iee. Anoaiiaeaii cieaeaio
ooieoe?iiaeueio aeoeai?noue O-noi?ani??a o oai?eo ia OeAe oa eaoa?aeoo ?
oea iaea?eueo ae?acii i?iyaeyeiny i?e OeAe I oeio. E?euee?noue
O-noi?ani??a o oai?eo ia OeAe I oeio neeaaeaea 162±26 ee/iee
(a??ia?aei?noue ??cieoe? c eiio?ieueiith a?oiith P<0,01), a o oai?eo ia OeAe II oeio ? o oai?eo ia a?eiao eaoa?aeoo 204±24 ee/iee ? 268±10 ee/iee a?aeiia?aeii (P<0,05). Anoaiiaeaii, ui iaiaeiicia/i? ci?ie ooieoe?iiaeueii? aeoeaiino? noaiiioeyoe?e O-e?ioioeeo?a o oai?eo ia OeAe oa eaoa?aeoo i?eaiaeeee aei ii?ooaiiy ?o ni?aa?aeiioaiiy ? oea aecia/aeinue o oaiaeaioe?? aei i?aeaeuaiiy ?ioii?aaoeyoi?iiai ?iaeaeno (???), ye o oai?eo ia OeAe I oeio (6,1±1,6), oae ? o oai?eo ia OeAe II oeio (5,2±2,7). Na?aaei?e ??aaiue oeueiai iieacieea o iaoe??io?a ia a?eiao eaoa?aeoo aoa o iaaeao ii?ie ? noaiiaea 3,8±0,8. Aecia/aia aeai?an?y ee?oeiii? eaiee ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio o oai?eo ia eaoa?aeoo ? OeAe aeicaiey? aeacaoe ia oa, ui o oeeo oai?eo ii?ooai? iaoai?cie O- noi?aneaiiai ?ioiieia?/iiai eiio?ieth, yeee caaacia/o? aooioiea?aioi?noue aei i?aaiiniaoeeo?/ieo aioeaai?a oeaiei iea, ui aoei i?aeoaa?aeaeaii anoaiiaeaiith iayai?noth nainea?e?caoe?? aei aioeaai?a e?eooaeeea oa noaeeiii? iaieiiee iea. Oae, o a?oiao oai?eo ia OeAe I oa II oeio a?aeiiniee iieaciee nainea?e?caoe?? aei aioeaai?a e?eooaeeea aei iia?aoe?? neeaaeaa 8,2±1,2% ? 8,8±1,6% a?aeiia?aeii, (P<0,05 aeey iaio a?oi o ii??aiyii? c ii?iith). A eiio?ieuei?e a?oi? oai?eo ia a?eiao eaoa?aeoo na?aaei?e ??aaiue nainea?e?caoe?? i?aai?cio aei AA oeaiei iea aoa aeaui aeuei o ii??aiyii? c ii?iith ? noaiiaea 5,6±1,0% (i?e ii?i? 3,0±1,0). Ci?ie aoii?aeueiiai ?ioi?oaoo oa?aeoa?ecoaaeenue ae?aaeaiei i?aeaeuaiiyi ai?noo ?ioiiaeiaoe?i?a eeano A a ia?eoa??ei?e e?ia? oai?eo ia OeAe oa eaoa?aeoo. Oae, yeui e?euee?noue IgA o oai?eo ia a?eiao eaoa?aeoo aoea a iaaeao ii?ie ? neeaaeaea 1,7±0,1 a/e, oi o a?oi? oai?eo ia OeAe I oeio aiia aei??aithaaea 3,1 ±0,42 a/e, a o a?oi? oai?eo ia OeAe II oeio aiia aoea 2,15±0,18 a/e, ui aecia/a? a??ia?aei? a?aei?iiino? oeueiai iieacieea o ii??aiyii? c oai?eie eiio?ieueii? a?oie (P<0,01 ? P<0,05). Ioe?iea aeeiai?ee iieaciee?a ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio o oai?eo ia eaoa?aeoo oa OeAe aei ? i?ney AAE c ?iieaioaoe??th ?IE iieacaea, ui i?ney iia?aoeaiiai ao?o/aiiy a ianoaaeaieo oai?eo i?e iayaiino? aeoeaaoe?? ianiaoeeo?/ieo oa niaoeeo?/ieo oaeoi??a ?ioiieia?/iiai caoenoo niinoa??aa?oueny caa?aaeaiiy oaeeo ii/aoeiaeo ?ioiiiaoieia?/ieo ii?ooaiue, ye iineaaeaiiy O-noi?ani?iiai ?ioiieia?/iiai eiio?ieth oa iayai?noue nainea?e?caoe?? i?aai?cio aei AA oeaiei iea (e?eooaeeea oa noaeeiii? iaieiiee). C iaoith aecia/aiiy iiaeeeaiai ca’yceo i?ae ii/aoeiaei noaiii ??I ? oa?aeoa?ii oa aaaee?noth i?iya?a i?neyiia?aoe?eiiai caiaeaiiy iea i?e i?iaaaeaii? AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe ??cieo oei?a aoei i?iaaaeaii ii??aiyeueiee aiae?c na?aaei?o ?ioiieia?/ieo iieaciee?a o a?oiao c ??cieie nooiaiyie i?iyao IC? iea (1 a?oia - neaaeee oa na?aaei?e nooiai? IC?, 2 a?oia - oai?? c neeueiith IC? iea). Anoaiiaeaii, ui iaea?eueo ae?aci? ci?ie a ni?aa?aeiioaii? ?ioii?aaoeyoi?-ieo noaiiioeyoe?e O-e?ioioeeo?a (O-oaeia??a/ T-noi?ani??a) niinoa??aaeenue o oai?eo ia OeAe II oeio c iani?eyoeeaei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo (2-a a?oia). O aeacai?e a?oi? oai?eo a?aei?/aii cieaeaiiy ye aaniethoii?, oae ? a?aeiinii? e?eueeino? O-noi?ani??a, aiane?aeie /iai niinoa??aaeinue cia/ia i?aeaeuaiiy ?ioii?aaoeyoi?iiai ?iaeaeno (???) a ii??aiyii? c iaoe??ioaie 1-i? a?oie. Aaniethoia e?euee?noue O-noi?ani??a a 1-e a?oi? aoea a iaaeao ii?ie aei ? i?ney iia?aoe?? ? noaiiaeea a?aeiia?aeii, 264±23 ? 386±18 ee/iee, a oie /an ye e?euee?noue O-noi?ani??a o oai?eo c oneeaaeiaiei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo aoea ??cei cieaeaiith ? neeaaeaea 95±22 ee/iee oa nooo?ai ia ci?ithaaeanue i?ney iia?aoe?? (132±21 ee/iee). O a?oi? oai?eo ia OeAe II oeio c ?icaeoeii i?ney AAE c ?iieaioaoe??th ?IE caiaeueii? ?aaeoe?? iea neeueiiai nooiaiy ??? aei iia?aoe?? neeaaeaa 10,1±0,3, ? caeeoaany oaeei aea aenieei i?ney iia?aoeaiiai ao?o/aiiy (9,4±0,21). O oai?eo ia OeAe ?c ni?eyoeeaei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo i?e AAE c ?iieaioaoe??th ?IE (neaaeee oa na?aaei?e nooiai? caiaeueii? ?aaeoe?? iea) ?ioii?aaoeyoi?iee ?iaeaen aoa a iaaeao ii?ie ? neeaaeaa aei ? i?ney iia?aoe?? 4,4±0,42 ? 4,6+0,44 a?aeiia?aeii. A?aei?iiino? iieaciee?a ??? aei ? i?ney iia?aoe?? o oai?eo ia OeAe oa eaoa?aeoo ?c ni?eyoeeaei ? oneeaaeiaiei ia?aa?aii i?neyiia?aoe?eiiai ia??iaeo ? a??ia?aeieie (P<0,001). ?acoeueoaoe ii??aiyeueiiai aiae?co ii/aoeiaiai noaio ??I a ianoaaeaieo oai?eo aeicaieeee anoaiiaeoe, ui i?e ii/aoeiaiio ??ai? ??? iiiaae 8,0, /anoioa neeueii? IC? i?e AAE c ?iieaioaoe??th ?IE a??ia?aeii aeua o oai?eo ia OeAe II oeio, ui aea? iiaeeea?noue aaaaeaoe aeacaia cia/aiiy ??? ye e?euee?niee iieaciee ?eceeo ?icaeoeo neeueii? IC? a i?neyiia?aoe?eiiio ia??iae?. Aeuacacia/aia aeicaiey? aeacaoe, ui iieaciee ??? ne?ae canoiniaoaaoe a i?aeoe/i?e iooaeueiieia?? ye ee?i?ei - ?ioiieia?/iee e?eoa??e i?iaiicoaaiiy ?icaeoeo neeueii? IC? iea i?e i?iaaaeaii? AAE c ?iieaioaoe??th ?IE o oai?eo ia eaoa?aeoo oa OeAe. Aoaeoeai?noue i?iaiicoaaiiy aaaeeino? i?neyiia?aoe?eii? caiaeueii? ?aaeoe?? i?e i?iaaaeaii? ?io?aieoey?ii? ei?aeoe?? o oai?eo ia oeoe?iaee ae?aaao. Aea/aii ?acoeueoaoe i?iaaaeaiiy ?io?aieoey?ii? ei?aeoe?? o 38 oai?eo ia OeAe II oeio, yeei aoea cae?eniaia AAE c ?iieaioaoe??th caaeiueieaia?iie ?IE (45 i/ae). I?e i?iaaaeaii? ?io?aieoey?ii? ei?aeoe?? o oeeo oai?eo a?aoiaoaaeenue oaeoi?e ?eceeo ?icaeoeo neeueii? IC?, ye? aoee aecia/aii ?ai?oa (OeAe aaaeeiai nooiaiy, iayai?noue i?ioa?io???, ??aaiue oeoe?o a e?ia? aeua 10,0 iiieue/e, ?ioii?aaoeyoi?iee ?iaeaen aeua 8,0). sseui a ia?aaeiia?aoe?eiiio ianoaaeaii? aeyaeyany aenieee ??aaiue oeoe?o a e?ia? (8 in?a), oai?? iai?aaeyeenue aei aiaeie?eiieiaa aeey ii?iae?caoe?? eiai ??aiy. A o 6 oai?eo ?c cia/aiiyi ???, aeuei ca 8,0 aoei i?iaaaeaii ?ioiiei?eaoth/o oa?ai?th eaaai?cieii (1350 ia ia eo?n e?eoaaiiy). Iia?aoe?th AAE c ?iieaioaoe??th ?IE aoei i?iaaaeaii i?ney ei?aeoe?? oeeo iieaciee?a. Eiio?ieueio a?oio neeaee oai?e ia OeAe II oeio oa eaoa?aeoo, yeei aoei i?iaaaeaii ?iieaioaoe?th ?IE aac a?aooaaiiy aeacaieo oaeoi??a. Noaoenoe/ii a??ia?aeii? ??cieoe? ca /eneii oai?eo c i?aeaeuaiei ?eceeii caiaeueieo oneeaaeiaiue i?e ia?aeiiiio caa?iaii? i?ae a?oiaie ia aoei. Aea/aiiy aaaeeino? caiaeueii? ?aaeoe?? i?ney AAE c ?iieaioaoe??th ?IE iieacaei, ui ia?aa?a i?neyiia?aoe?eiiai ia??iaeo aoa a?eueo ni?eyoeeaei o aeaii? a?oie oai?eo o ii??aiyii? c iaa?ae?a?aiith a?oiith oai?eo ia OeAe II oeio. Oae, IC? neeueiiai nooiaiy niinoa??aaeinue a 11,1% aeiaaee?a, a oie /an ye i?e iia?aoe??, yeo aoei i?iaaaeaii aac a?aooaaiiy oaeoi??a ?eceeo caiaeueieo oneeaaeiaiue /anoioa neeueii? IC? noaiiaeea 21,6%. O 46,6% ? 42,2% aeiaaee?a niinoa??aaeinue IC? neaaeiai oa na?aaeiueiai nooiaiy, a?aeiia?aeii. sse iieacaee a?aeaeaeai? niinoa?aaeaiiy, ye? aoee i?iaaaeai? o 34 oai?eo c iniiaii? a?oie oai?eo ia OeAe II oeio, (39 i/ae), ci?ia? ooieoe?? cia/ii iie?aueeenue ia i?ioyc? ia?oiai ?ieo i?ney iia?aoeaiiai ao?o/aiiy. sseui i?e aeienoe? aino?ioa ci?o 0,5 ? aeua niinoa??aaeanue o 16 aeiaaeeao ?c 45 (35,6%), /a?ac 1 ??e i?ney iia?aoe?? AAE c ?iieaioaoe??th ?IE aino?ioa ci?o 0,5 ? aeua niinoa??aaeinue a 33 aeiaaeeao ?c 39 (84,6%), ui aoei a??ia?aeii aeua, i?ae o eiio?ieuei?e a?oi? (67,8%; P<0,05). Aeniiaee 1. I?aeaeuaiiy aoaeoeaiino? iia?aoe?? AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe ? aeooaeueiith i?iaeaiith no/anii? iooaeueiio??o?a?? /a?ac aenieo /anoioo i?neyiia?aoe?eieo oneeaaeiaiue, a ia?oo /a?ao caiaeueiiai oa?aeoa?o ? a?aeiinii iecueeeo ooieoe?iiaeueieo ?acoeueoao?a o ii??aiyii? c ?acoeueoaoaie iia?aoe?e c i?eaiaeo iaoneeaaeiaii? a?eiai? eaoa?aeoe. 2. Ii??aiyeueiee aiae?c ae?aaeaiiino? i?neyiia?aoe?eii? caiaeueii? ?aaeoe?? iea i?e AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe oa eaoa?aeoo ? o oai?eo ia a?eiao eaoa?aeoo aeyaea a?eueo aenieo /anoioo aaaeeiai i?neiia?aoe?eiiai caiaeaiiy iea o oai?eo ia OeAe, i?ae o a?oi? ii??aiyiiy. I?neyiia?aoe?eia caiaeueia ?aaeoe?y neeueiiai nooiaiy niinoa??aaeanue o oai?eo ia OeAe I ? II oeio a 37,5% ? 21,6% aeiaaee?a, a?aeiia?aeii, a o oai?eo ia a?eiao eaoa?aeoo a 7,9% aeiaaee?a. 3. O oai?eo ia OeAe ? eaoa?aeoo niinoa??aathoueny ii?ooaiiy o noai? ee?oeiiiai ?ioieoaoo o aeaeyae? i?eai?/aiiy ooieoe?iiaeueii? aeoeaiino? O-noi?ani??a ? aenieee ??aaiue nainea?e?caoe?? i?aai?cio aei aioeaai?a noaeeiii? iaieiiee iea oa e?eooaeeea, a?eueo ae?aaeai? i?e ?inoe?icaeaaeiiio oeio OeAe. 4. Iani?eyoeeaeie ee?i?/ieie i?iaiinoe/ieie e?eoa??yie uiaei ?icaeoeo neeueii? caiaeueii? ?aaeoe?? iea i?ney AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe II oeio ? eaoa?aeoo ? oae?: OeAe aaaeeiai nooiaiy, iayai?noue i?ioa?io???, a oaeiae ??aaiue oeoe?o a e?ia? iiiaae 10,0 iiieue/e, a oaeiae ii/aoeiaee ??aaiue ?ioii?aaoeyoi?iiai ?iaeaeno (ni?aa?aeiioaiiy O-oaeia??a/O-noi?ani??a) aeuee ca 8,0. 5. Ioe?iea ee?i?/ii? aoaeoeaiino? ?io?aieoey?ii? ei?aeoe?? o oai?eo ia OeAe II oeio oa eaoa?aeoo iieacaea, ui ?c a?aooaaiiyi oaeoi??a ?eceeo caiaeueieo oneeaaeiaiue aenie? ooieoe?iiaeuei? ?acoeueoaoe (aino?ioa ci?o 0,5 ? aeua) i?e AAE c ?iieaioaoe??th ?IE aaeaeinue io?eiaoe a 84,6% aeiaaee?a o ii??aiyii? c 67,8% aeiaaee?a o iaa?ae?a?ai?e a?oi? iia?iaaieo oai?eo. Nienie iaoeiaeo i?aoeue, iioae?eiaaieo ca oaiith aeena?oaoe??: 1. Aeaaoy?aiei O.A., Ia?aoyaei I.A., Ea?eiia I.E. Iniaaiiinoe eiioiiiai noaoona o aieueiuo naoa?iui aeeaaaoii n ?acee/iie oyaeanoueth ainiaeeoaeueiie ?aaeoeee iinea yeno?aeainoey?iie yeno?aeoeee eaoa?aeou n eiieaioaoeeae eio?aieoey?iuo eeic //Iooaeueiie. aeo?i.-1998.-?4.-N.287-291. 2. Aeaaoy?aiei O.A., Ia?aoya?i I.A., Ea??iia I.?. ?ioiieia?/ia ?aaeoeai?noue i?aai?cio o oai?eo ia oeoe?ia?e ae?aaao ?c ??cieie ee?i?/ieie i?iyaaie caiaeueii? ?aaeoe?? iea i?ney aeno?aeainoey?ii? aeno?aeoe?? eaoa?aeoe c ?iieaioaoe??th ?io?aieoey?ieo e?ic // Iaeanueeee iaae. aeo?i. - 1999. -?2 N.38-40. 3. Aeaaoy?aiei O.A., Ia?aoyaei I.A., Ea?eiia I.E. Cia/aiea ia?ooaiee eiioiieiae/aneie ?aaeoeaiinoe a ?acaeoee ainiaeeoaeueiie ?aaeoeee a aeaco o aieueiuo naoa?iui aeeaaaoii i?e eiieaioaoeee eio?aieoey?iuo eeic // Ca. iaoe. i?aoeue “I?iaeaie aeieia?/ii? oa iaaee/ii? aaiaoeee ? ee?i?/ii? ?ioiieia??”. - Aei.1 (21). - Ee?a - Eoaainuee, 1999. - N.62-69. 4. Ea?eiia I.E. Eeeie/aneea ?acoeueoaou yeno?aeainoey?iie yeno?aeoeee eaoa?aeou n eiieaioaoeeae caaeiaeaia?iuo eio?aieoey?iuo eeic o aieueiuo naoa?iui aeeaaaoii // Iooaeueiie. aeo?i.-1999, -?1, - N.5-8. 5. Ea?eiia I.E., Ia?aoyaei I.A. Iniaaiiinoe eiioiieiae/aneie ?aaeoeaiinoe i?aaiecia o aieueiuo naoa?iui aeeaaaoii i?e yeno?aeainoey?iie yeno?aeoeee eaoa?aeou (YYE) n eiieaioaoeeeae eio?aieoey?iuo eeic (EIE) // Oac. aeiee. iaoe. eiio. iooaeueiieia?a, i?enay/aii? 90-??//th aeaae. I.I.Io/eianueei?. -Iaeana, Oe?a?ia, 1998. - N.409-411. aiioaoe?y Ea??iia I.?. Ee?i?ei-?ioiieia?/i? iniaeeaino? caiaeueii? ?aaeoe?? iea i?e aeno?aeaioey?i?e aeno?aeoe?? eaoa?aeoe c ?iieaioaoe??th ?io?aieoey?ieo e?ic o oai?eo ia oeoe?ia?e ae?aaao.-?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.18. - i/i? oai?iae. - ?inoeooo i/ieo oai?ia ? oeaieiii? oa?ai?? ?i. A.I.O?eaoiaa AII Oe?a?ie, Iaeana, 1999. Aeaia aeena?oaoe?eia ?iaioa yaey? niaith ee?i?/iee aiae?c ?acoeueoao?a aeno?aeainoey?ii? aeno?aeoe?? eaoa?aeoe (AAE) c ?iieaioaoe??th caaeiueieaia?ieo ?io?aieoey?ieo e?ic (?IE) o 215 oai?eo ia eaoa?aeoo, c yeeo 11 oai?eo ia OeAe I oeio ? 128 oai?eo ia OeAe II oeio. Anoaiiaeaii, ui iayai?noue i?ioa?io???, aaaeeee nooi?iue OeAe, a?ia?ae?eai?y aeua ca 10,0 iiieue/e, i?aeaeuaiiy ?ioii?aaoeyoi?iiai ?iaeaeno iiiaae 8,0 ? nooo?aeie oaeoi?aie ?eceeo neeueii? caiaeueii? ?aaeoe?? iea i?ney AAE c ?iieaioaoe??th ?IE o oai?eo ia OeAe II oeio. Iaea?eueo ni?eyoeeaee ia?aa?a i?neyiia?aoe?eiiai ia??iaeo ? e?au? ooieoe?iiaeuei? ?acoeueoaoe AAE c ?iieaioaoe??th ?IE niinoa??aathoueny o oai?eo ia OeAe II oeio aac aeuacacia/aieo oaeoi?ia ?eceeo. ?aeiiaiaeo?oueny a?aoiaoaaoe aeai? ia?aaeiia?aoe?eieo ee?i?/ieo ? ?ioiieia?/ieo ianoaaeaiue aeey aecia/aiiy oaeoeee e?eoaaiiy eaoa?aeoe o oai?eo ia OeAe. Eeth/ia? neiaa: aeno?aeainoey?ia aeno?aeoe?y eaoa?aeoe, ?io?aieoey?i? e?ice, caiaeueia ?aaeoe?y, ?ioiieia?/ia ianoaaeaiiy, oeoe?iaee ae?aaao. aiiioaoeey Ea?eiia I.E. Eeeieei-eiioiieiae/aneea iniaaiiinoe ainiaeeoaeueiie ?aaeoeee a aeaco i?e yeno?aeaioey?iie yeno?aeoeee eaoa?aeou n eiieaioaoeeae eio?aieoey?iuo eeic o aieueiuo naoa?iui aeeaaaoii.-?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.18. - aeaciua aieacie.- Einoeooo aeaciuo aieaciae e oeaiaaie oa?aiee ei. A.I.Oeeaoiaa AII Oe?aeiu, Iaeanna, 1999. Caueuaaony aeenna?oaoeeiiiay ?aaioa, i?aaenoaaeythuay niaie aiaeec ?acoeueoaoia yeno?aeainoey?iie yeno?aeoeee eaoa?aeou (YYE) n eiieaioaoeeae EIE o 215 aieueiuo (239 aeac), ec eioi?uo 11 aieueiuo eaoa?aeoie e naoa?iui aeeaaaoii (NAe) I oeia (16 aeac), 128 aieueiuo eaoa?aeoie e NAe II oeia (147 aeac) e 76 aieueiuo aic?anoiie eaoa?aeoie (76 aeac). Aeey ioeaiee iineaiia?aoeeiiiiai oa/aiey iinea YYE n eiieaioaoeeae EIE i?iaiaeeeny aiaeec oyaeanoe ainiaeeoaeueiie ?aaeoeee a aeaco ii o?ao-aaeeueiie oeaea, i?aaeeiaeaiiie I.I.Na?aeaiei e C.O.Aanaeianeie (1985,1990). Oa/aiea iineaiia?aoeeiiiiai ia?eiaea auei aieaa aeaaii?eyoiui o aieueiuo n aic?anoiie eaoa?aeoie ii n?aaiaieth n oaeiaui o aieueiuo eaoa?aeoie, no?aaeathueo NAe. Iineaiia?aoeeiiiay ainiaeeoaeueiay ?aaeoeey III (neeueiie) noaiaie iaaethaeaeanue o 7,9% aieueiuo aic?anoiie eaoa?aeoie, o 21,6% aieueiuo NAe II oeia e o 37,5% aieueiuo NAe I oeia. I?ia?anne?iaaiea Ae?I (?acaeoea Ae?I eee onoaoaeaiea eiaaoeony aeeaaaoe/aneeo eciaiaiee nao/aoee) ca ia?eiae iaaethaeaeinue a 21 neo/aa, ec ieo a 9-oe neo/ayo a ia?aue aiae iinea iia?aoeaiiai aiaoaoaeuenoaa (8,4% ceo/aaa), /oi auei ianeieueei ieaea, /ai aeaiiua i?eaaaeaiiua a eeoa?aoo?a. Eae iieacaee iaaethaeaiey ioaeaeaiiiai ia?eiaea, oyaeaeia oa/aiea iineaiia?aoeeiiiiai ia?eiaea ia?yaeo n eciaiaieyie nao/aoee aeeaaaoe/aneiai aaiaca, yaeyaony cia/eoaeueiui oaeoi?ii, aeeythuei ia eiia/ioth ino?ioo c?aiey. E?iia oiai, ianiio?y ia eioaineaioth i?ioeaiainiaeeoaeueioth oa?aieth, i?e neeueiie IA? /anoi nio?aiyeenue caaeiea neiaoee, i?eaiaeyuea e aeaoi?iaoeee c?a/ea, cao?oaeiaieth aai ?anoe?aiey e i?iaaaeaiey aaeaeaaoiiai iooaeueiineiie/aneiai eiio?iey e eaca?eiaaoeyoeee o aeaiiuo aieueiuo. Ia iniiaaiee eco/aiey enoiaeiiai ninoiyiey i?aaiecia e oa/aiey iineaiia?aoeeiiiiai ia?eiaea onoaiiaeaii, /oi iaee/ea i?ioaeio?ee, oyaeaeay noaiaiue NAe, aeia?aeeeaiey auoa 10,0 iiieue/e, yaeythony oaeoi?aie ?enea ?acaeoey neeueiie IA? i?e YYE n eiieaioaoeeae EIE o aieueiuo NAe II oeia. Ia auyaeaii aeinoiaa?iie ei??aeyoeee iaaeaeo aic?anoii, iieii aieueiuo, aeeeoaeueiinoueth caaieaaaiey aeeaaaoii, iaee/eai Ae?I e oyaeanoueth IA? neeueiie noaiaie a aeaco o aieueiuo NAe i?e YYE n eiieaioaoeeae EIE. O 11 aieueiuo NAe I oeia, 45 aieueiuo NAe II oeia, e o 40 aieueiuo aic?anoiie eaoa?aeoie ec eiio?ieueiie a?oiiu, iiaeaa?aoeony YYE n eiieaioaoeeae EIE i?iaiaeeeinue eiioiieiae/aneia ianeaaeiaaiea aei e iinea iia?aoeaiiai aiaoaoaeuenoaa. Eco/aiea eiioiieiae/aneie ?aaeoeaiinoe i?aaiecia iieacaei, /oi o aieueiuo eaoa?aeoie, no?aaeathueo NAe, eiathony ia?ooaiey ninoiyiey eiioiieiae/aneie ?aaeoeaiinoe i?aaiecia, eioi?ua i?iyaeythony a aeai?annee O-noi?anni?iiai caaia eeaoi/iiai eiioieoaoa, iiauoaiee niaea?aeaiey IgA a ieacia e?iae, a oaeaea a iaee/ee aooinaineaeeecaoeee e aioeaaiai ninoaeenoie iaiei/ee aeaca e o?onoaeeea. Ii?aaeaeaia iieiaeeoaeueiay ei??aeyoeey iaaeaeo enoiaeiui o?iaiai eiioii?aaoeyoi?iiai eiaeaena (niioiioaiea O-oaeia?ia/O-noi?anni?ia) e oyaeanoueth IA? o aieueiuo NAe, iiaeaa?aoeony YYE n eiieaioaoeeae EIE, a iiauoaiea yoiai iieacaoaey auoa 8,0 yaeyaony oaeoi?aie ?enea neeueiie ainiaeeoaeueiie ?aaeoeee iinea YYE n eiieaioaoeeae EIE o aieueiuo NAe II oeia. Eco/aiu ?acoeueoaou i?iaaaeaiey eio?aieoey?iie ei??aeoeee o 38 aieueiuo NAe II oeia, eioi?ui auea i?iecaaaeaia YYE eiieaioaoeeae EIE (45 aeac). I?e i?iaaaeaiee iia?aoeaiiai aiaoaoaeuenoaa i?eieiaeenue ia?u ii auyaeaieth oaeoi?ia ?enea ?acaeoey neeueiie IA? e eo ei??aeoeee. Oa/aiea iineaiia?aoeeiiiiai ia?eiaea auea aieaa aeaaii?eyoiui o aeaiiie a?oiiu aieueiuo a n?aaiaiee n iaioia?aiiie a?oiiie iia?e?iaaiiuo aieueiuo NAe. Oae, IA? neeueiie noaiaie iaaethaeaeinue a 11,1% neo/aaa, a oi a?aiy eae i?e a a?oiia n?aaiaiey /anoioa neeueiie IA? ninoaaeyea 21,6% (P<0,05). Oaeaea oaeaeinue iiauneoue ooieoeeiiaeueioth yooaeoeaiinoue (ino?ioa c?aiey 0,5 e auoa) YYE n eiieaioaoeeae EIE ia 14,8%. Aiaae?aiea ?acoeueoaoia enneaaeiaaiey a iooaeueiieiae/aneoth i?aeoeeo aoaeao niinianoaiaaoue iiauoaieth o?iaiy ?aaaeeeoaoeee aieueiuo eaoa?aeoie, no?aaeathueo naoa?iui aeeaaaoii. Eeth/aaua neiaa: yeno?aeainoey?iay yeno?aeoeey eaoa?aeou, eio?aieoey?iua eeicu, ainiaeeoaeueiay ?aaeoeey, eiioiieiae/aneia ianeaaeiaaiea, naoa?iue aeeaaao. abstract Kerimov M.I. Clinical and immunological aspects of ocular inflammatory reaction after extracapsular cataract extraction with IOL implantation in patients with diabetes mellitus. - Manuscript. Thesis for the candidate’s degree by speciality -14.01.18. -eye diseases. - The Filatov Institute of Eye Diseases and Tissue Therapy, The AMSci of Ukraine, Odessa, 1999. The thesis presented contains the analysis of extracapsular cataract extraction (ECCE) with IOL implantation results in 215 patients, from which 11 patients were with type I and 128 patients with type II diabetes mellitus and cataract. The study revealed proteinuria, severe diabetes, hyperglycaemia >10,0 mmol/l and elevated “immunoregulatory
index” (T-helpers/ T-suppressors) above 8,0 as risk factors for severe
inflammatory reaction after ECCE + IOL implantation in patients with
type II diabetes mellitus. Better results of ECCE + IOL in type II
diabetics obtained in patients without these risk factors. The thesis
recommends consideration of preoperative clinical and immunological
examination data in the management of cataract in diabetic patients.

Key words: extracapsular cataract extraction, intraocular lenses,
inflammatory reaction,immunological examination, diabetes mellitus.

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