2

I?I?NOA?NOAI IOI?IIE CAeI?IAss OE?A?IE

?AAII-O?AIE?ANUeEA AeA?AEAAIA IAAeE*IA AEAAeAI?ss

Ia i?aaao ?oeiieno

IAOOUAE IEUeAA IEEIEA?AIA

OAeE: 616. 342–002.44–085.356–085.322–092.19

EE?I?EI–?IOIIEIA?*I? INIAEEAINO? AE?ACEIAI? OAI?IAE AeAAIAAeOessOEIAEI?
EEOEE I?E EIIIEAENI?E OA?AI?? C AEETH*AIIssI
A?OAI?IO A OA AO?IAOeA? IO?IO?II?

14.01.02 AIOO??OI? OAI?IAE

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

?AAII–O?AIE?ANUeE – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Euea?anueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?
?iai? Aeaieea Aaeeoeueeiai.

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe, i?ioani?

Aeooea ?iiai ss?ineaaiae/,

Euea?anueeee aea?aeaaiee
iaaee/iee oi?aa?neoao

?iai? Aeaieea Aaeeoeueeiai IIC
Oe?a?ie,

caa?aeoaa/ eaoaae?e
i?iiaaeaaoeee aioo??oi?o oai?ia

Io?oe?ei? iiiiaioe:

1. Aeieoi? iaaee/ieo iaoe, i?ioani? I?uoe Aaneeue A?eai?iae/,

?aaii-O?aie?anueea aea?aeaaia iaaee/ia aeaaeai?y IIC Oe?a?ie,

i?ioani? eaoaae?e oa?ai?? oaeoeueoaoo i?neyaeeieiiii? ina?oe

2. Aeieoi? iaaee/ieo iaoe, i?ioani? Aiio?ia Aaeeia Aiaoie??aia,

Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?iai? I.E. Ooieea
IIC Oe?a?ie,

i?ioani? eaoaae?e aano?iaioa?ieia?? oa ae??oioa?ai??

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee
oi?aa?neoao

?i. aeaaeai?ea
I.I.Aiaiiieueoey,

eaoaae?a
aini?oaeueii? oa?ai?? ? 2 (i. Ee?a)

Caoeno a?aeaoaeaoueny _30_” _ea?oiy_ 1999 ?ieo ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 20.601.01. o ?aaii-O?aie?anuee?e
aea?aeaai?e iaaee/i?e aeaaeai?? (284000, i. ?aaii-O?aie?anuee, aoe.
Aaeeoeueea, 2).

C aeena?oaoe??th iiaeia iciaeiieoeny a a?ae?ioaoe? ?aaii-O?aie?anueei?
aea?aeaaii? iaaee/ii? aeaaeai?? (284000, i.?aaii-O?aie?anuee,
aoe.Aaeeoeueea, 7).

Aaoi?aoa?ao ?ic?neaiee __19 aa?aciy 1999?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

aeieoi? iaaee/ieo iaoe, i?ioani?
I. A. I?ei/ae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. I?iaeaia ae?aceiai? oai?iae aeaaiaaeoeyoeiaei?
eeoee (AOAeIE) ia nueiaiaei? iiai?noth caa??aa? naith aeooaeuei?noue ye
a oai?aoe/iiio, oae ? a i?aeoe/iiio a?aeiioaii?. Ae?aceiaa oai?iaa
caeeoa?oueny iaea?eueo iioe?aiei caoai?thaaiiyi i?aai?a o?aaeaiiy, a ca
inoaii? aeanyoe??//y noaeiny iaa?oue c?inoaiiy caoai?thaaiino?
(Ia?aaea?ee A.A. e niaao., 1997; Aaeaiei C.I., 1995).

I?eioeeiia? ieoaiiy ao?ieia??, iaoiaaiaco, ae?aaiinoeee oa e?eoaaiiy
ae?aceiaeo o?aaeaiue aano?iaeoiaeaiaeueii? ciie aeoeaii aeeneooothoueny
a iaoeia?e e?oa?aoo??, i?ioa caeeoathoueny aeaeaeeie a?ae inoaoi/iiai
c’ynoaaiiy. O?ii?/ia ?aoeeaeeaoth/a i?io?eaiiy, iie?ii?o?ci ee?i?/ieo
i?iya?a ? aaaee? oneeaaeiaiiy ae?aceiai? oai?iae 12-iaei? eeoee, a
oaeiae cynoaaiiy ?ie? oae?eiaaeoa?ii? ?ioaeoe?? a ?icaeoeo caoai?thaaiiy
aeacothoue ia caoe?eaaeai?noue ?ioiii? nenoaie a aaiac? oai?iae.

Iane?aeie oiai /e ?ioiai iaoieia?/iiai i?ioeano a e?ioeaaiio i?aenoieo
aecia/a?oueny ye oni?oiei e?eoaaiiyi, oae ? noaiii iae?ii?aai?cio, eiai
?aaeoeai?noth. Oi?ioaaiiy O-ee?oeiiiai ?ioiiaeao?oeeoo, ia?aaaaeii ca
?aooiie cieaeaiiy ??aiy O-oaeia??a ia oii? i?aeaeuaiiai ??aiy Ig A ?
ca?eueoaiiy ai?noo A-e?ioioeeo?a, i?aeaeuaiiy ??aiy oee?eoethth/eo
?ioiieo eiiieaen?a (Oe?E) oa ??aiy I-e?ioioeeo?a oa?aeoa?i? aeey AOAeIE
? iinyoue ianiaoeeo?/iee oa?aeoa? (Ia?aaea?ee A.A. e niaao., 1997;
Aeaaoy?ueiaa ?.?. ? ni?aaao., 1992; Iaeauoe A.I. ? ni?aaao., 1995; Kluge
A. et al., 1993; Begum S. et al., 1992). Ia aeeaey/enue ia iayai?noue
ci?i ?ioiii? nenoaie, a?aenooi? aeai? uiaei /?oeiai iaa?oiooaaiiy
canoinoaaiiy ?ioiiiiaeoethth/i? oa?ai?? i?e ae?aceia?e oai?ia? ? a
?acoeueoao? oeueiai iica oaaaith caeeoa?oueny iaeia c iaea?eueo
aaaeeeaeo nenoai — ?ioiia nenoaia.

Caaaeueiia?aeiii, ui a e?eoaaii? ae?aceiai? oai?iae, a iniiaiiio,
aeei?enoiaothoueny na?aaeieee, aeieoth/? eeneioiaeae?eaiiy, ci?ie yeiai
? iaeiei ?c e?ioeaaeo iane?aee?a ii?ooaiiy ??cieo iaoai?ci?a,
aeeth/ath/e ?ioii?. I?ioa, aei oeueiai /ano iaaeinoaoiuei aea/aiee aieea
?ioiiiiaeoeyoi??a ia iieacieee ?ioiiiai noaio oai?eo AOAeIE. Na?aae
?ioiiiiaeoethth/eo cania?a i?e e?eoaaii? ??cieo caoai?thaaiue iaea?eueo
aea/aieie ? ioeea?iao iao??th, O-aeoea?i, a?eicai, c?eni?ei, o?iae?i
(Naethe I.E., 1992; Eaoa?ai/oe ?.I., 1996; Aeoaea?ue E.A., 1994; Ia?eea
E.I., 1991). I?ioa oe? i?aia?aoe ia iicaaaeai? iia?/ieo aoaeo?a, ui
iaiaaeo? ?o aaeeaaiiy, iniaeeai o oai?eo ae?aceiaith oai?iaith, yea
/anoi niinoa??aa?oueny o in?a iieiaeiai oa na?aaeiueiai a?eo.

Iaeieie ?c iaea?eueo aacia/ieo e?eoaaeueieo na?aaeiee?a ?
o?oina?aaeieee oa i?e?iaei? aioeieneaeaioe (*aeiai ?.N., 1996).

Na?aae aeaii? a?oie caneoaiao? oaaae a?o/eciyiee i?aia?ao ianoieea
ao?iaoea? io?io?ii?, aoaeoeai?noue yei?, ye ?ioiiiiaeoeyoi?a, aeiaaaeaia
i?e oe?eiio ?yae? caoai?thaaiue, aeeth/ath/e a??oni?, ?aaiaoi?aeiee
a?o?eo, oeoe?iaee ae?aaao, o?ii?/iee aeiia?oeiiao?eo (Iaoiiaa I.?.,
1997; Zoutewelle G., 1990; Aeoae/aiei E.A., 1991; Iai/o? O.?., 1993).
I?ioa, ii a?aeiioaiith aei AOAeIE aoaeoeai?noue aeaiiai caniao a
ee?i?oe? ia aea/aeany.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?y
aeeiiaia ca?aeii c ieaiii IAe? Euea?anueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo ?iai? Aeaieea Aaeeoeueeiai Ae? ?I.25.01.0003.96
I?iaiicoaaiiy i?ia?aae??ioiino? o?ii?/ieo caoai?thaaiue”.

Iaoith aeaiiai aeine?aeaeaiiy ? aea/aiiy aoaeoeaiino? eiiieaenii?
oa?ai?? c aeeth/aiiyi ?ioiiiiaeoeyoi?a ianoieee ao?iaoea? io?io?ii? oa
a?oai?io A (-oieioa?ieo aoeaoaoo) ia ee?i?ei-?ioiieia?/i? iieacieee o
oai?eo ae?aceiaith oai?iaith 12-iaei? eeoee.

O a?aeiia?aeiino? c iinoaaeaiith iaoith, aecia/ai? caaaeaiiy
aeine?aeaeaiiy

1. I?iaanoe aea/aiiy ?ioiiiai noaio oai?eo c AOAeIE ii iieacieeao
oee?eoethth/eo ?ioiieo eiiieaen?a (Oe?E), oieiaeiaeo ?ioiieo eiiieaen?a
(O?E), ne?iaaoei-noi?ani?iiai oaeoi?o (NNO) oa ?ioii?aaoeyoi?iiai
?iaeaeno (???) a ne?iaaooe? e?ia?.

2. I?iaanoe aiae?c ?ioiieia?/ieo iieaciee?a Oe?E, O?E, NNO oa ??? o
oai?eo c AOAeIE a caeaaeiino? a?ae a?eo, o?eaaeino? caoai?thaaiiy,
aaaeeino? oa aaee/eie ae?aceiaiai aeaoaeoo.

3. Aea/eoe aieea aacenii? i?ioeae?aceiai? oa?ai?? ia ?ioiiee noai
oai?eo AOAeIE.

4. Aea/eoe aieea eiiieaenii? oa?ai?? c aeeth/aiiyi ?ioiiiiaeoeyoi?a
ao?iaoea? io?io?ii? oa -oieioa?ieo aoeaoaoo ia ai?no Oe?E, O?E, NNO oa
??? a ne?iaaooe? e?ia? oai?eo AOAeIE.

5. I?iaanoe ii??aiyeueiee aiae?c ee?i?ei-aiaeineii?/ii-?ioiieia?/ii?
aoaeoeaiino? eiiieaenii? oa?ai?? c aeei?enoaiiyi ianoieee ao?iaoea?
io?io?ii? oa a?oai?io A c aaceniith i?ioeae?aceiaith oa?ai??th o oai?eo
AOAeIE.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa a oiiaao ee?i?ee
anoaiiaeaii, ui caaino?aiiy AOAeIE noi?iaiaeaeo?oueny ?ioiieia?/iei
aeenaaeainii, yeee oa?aeoa?eco?oueny ia o?eueee cieaeaiiyi
?ioii?aaoeyoi?iiai ?iaeaeno, i?aeaeuaiiyi Oe?E, aea e ca?eueoaiiyi O?E
oa NNO. Aeyaeaii ci?ie ?ioiieia?/ieo iieaciee?a a caeaaeiino? a?ae
aaaeeino? caoai?thaaiiy. Iaa?oioiaaii iaiao?aei?noue i?iaaaeaiiy
?ioii?aaoethth/i? oa?ai?? o oai?eo AOAeIE. Aea/aii aieea eiiieaenii?
oa?ai?? c aeeth/aiiyi ?ioiiiiaeoeyoi?a ?ineeiiiai iioiaeaeaiiy —
ianoieee ao?iaoea? io?io?ii? a ii?aeiaii? c a?oai?iii A ia iieacieee
?ioi?oaoo Oe?E, O?E, NNO oa ??? o oai?eo AOAeIE. Aeiaaaeaia
ee?i?ei-aiaeineii?/ia oa ?ioiieia?/ia aoaeoeai?noue aeacaii? oa?ai?? o
oai?eo AOAeIE.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Ia iniia? io?eiaieo
?acoeueoao?a iaa?oioiaaii iiaee i?aeo?ae aei aeai?o iaoiae?a e?eoaaiiy
oai?eo AOAeIE ? aeiaaaeaia ee?i?/ia, aiaeineii?/ia oa ?ioiieia?/ia
aoaeoeai?noue aeeth/aiiy a eiiieaenio oa?ai?th ?ioiiiiaeoethth/iai
na?aaeieea ?ineeiiiai iioiaeaeaiiy — ao?iaoea? io?io?ii? oa a?oai?ia E.
Canoinoaaiiy ?ioiiiiaeoeyoi?a ao?iaoea? io?io?ii? oa aioeieneaeaioa
a?oai?ia A aeicaiey? a a?eueo ei?ioeee oa?i?i aeinyaiooe ee?i?/ii? oa
aiaeineii?/ii? ?ai?n?? ae?aceiai? oai?iae, ciaioeoe e?euee?noue
?aoeeaeea?a caoai?thaaiiy, a oaeiae e?ea?aeoaaoe aoi?eiiee
?ioiiaeao?oeeo, ui ia? i?noea o oeeo oai?eo. Aaaeeeaa i?aeoe/ia cia/aiiy
io?eiaieo ?acoeueoao?a iieyaa? oaeiae a oiio, ui a yeino?
?ioiiiiaeoeyoi??a aeei?enoai? a?o/eciyi?, aeinooii? aeey oai?eo
i?aia?aoe, ye? ? i?e?iaeieie caniaaie c i?i?iaeueiith e?euee?noth
iia?/ieo ae?e, ui ?iaeoue ?o aacia/ieie aeey oe?ieiai canoinoaaiiy a
i?aeoeoe? e?ea?y.

Io?eiai? ?acoeueoaoe aeei?enoiaothoueny a iaa/aeueii–iaaeaaia?/iiio
i?ioean? ia eaoaae?? i?iiaaeaaoeee aioo??oi?o oai?ia Euea?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i. Aeaieea Aaeeoeueeiai.
?acoeueoaoe aeine?aeaeaiue c iiceoeaiei aoaeoii ai?iaaaeaeaii a
i?aeoe/io ae?yeuei?noue aano?iaioa?ieia?/ieo a?aeae?eaiue 1 oa ? 2
e?ea?i? ? 5 i.Eueaiaa, aano?iaioa?ieia?/iiai a?aeae?eaiiy e?ea?i? ? 30
I?inueeiai ?aeiio i. Ee?aa, iaeaniiai ee?i?/iiai aano?iaioa?ieia?/iiai
aeeniaina?o i.Oaeai?iaea oa oa?aiaaoe/iiai a?aeae?eaiiy No?eenueei?
oeaio?aeueii? ?aeiiii? e?ea?i? Euea?anueei? iaeano?.

Iniaenoee aianie caeiaoaa/a. Aeena?oaoe?eia ?iaioa ? caaa?oaiei
naiino?eiei iaoeiaei aeine?aeaeaiiyi I.I.Iaoouae. Aaoi? iinoaaeea iaoo
oa caaaeaiiy iaoeiai? ?iaioe, i?iaiae?coaaea iaoeiao e?oa?aoo?o ii
aeai?e i?iaeai?, noi?ioaaea ee?i?/i? a?oie iaoe??io?a. Aiae?c oa
?ioa?i?aoaoe?y aeaieo ee?i?/ii-eaai?aoi?iiai, ?ioiieia?/iiai oa
?ino?oiaioaeueiiai ianoaaeaiue cae?eniaia aeena?oaioii. Iniaenoi aaoi?ii
c?iaeaia noaoenoe/ia ia?iaea ?acoeueoao?a, iaienai? an? ?icae?ee
aeena?oaoe??.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. ?acoeueoaoe aeine?aeaeaiue oa
iniiai? iieiaeaiiy ?iaioe aena?oeaii a aeiiia?aeyo ia can?aeaii?
eaoaae?e i?iiaaeaaoeee aioo??oi?o oai?ia Euea?anueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo (1998), ia can?aeaii? iaeaniiai oiaa?enoaa
aano?iaioa?ieia?a (Euea?a, 1998), 14 c’?cae? oa?aiaao?a Oe?a?ie (1998).

Ioae?eaoe??. Ca iaoa??aeaie aeena?oaoe?? iioae?eiaaii 8 ae?oeiaaieo
i?aoeue o iaoeiaeo aeo?iaeao oa ca??ieeao iaoa??ae?a eiioa?aioe?e,
c?caeo.

Ia?i oa no?oeoo?a ?iaioe. Aeena?oaoe?y aeeeaaeaia ia 142 noi??ieao
iaoeiiieno, neeaaea?oueny c anooio, 4 ?icae?e?a, iaaiai?aiiy iaea?aeaieo
?acoeueoao?a, aeniiae?a, aeiaeaoe?a. ?iaioa ?ethno?iaaia 31
oaaeeoeath, 15 ?enoieaie. Nienie e?oa?aoo?e i?noeoue 205 aeaea?ae.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy.

Aeey ae??oaiiy iinoaaeaieo a ?iaio? caaaeaiue aoei ianoaaeaii 184
iaoe??ioe, c ieo 134 — oai?? AOAeIE, 50 — i?aeoe/ii caei?ia? ethaee.

A?e oai?eo eieeaaany a?ae 17 aei 65 ?ie?a. ?iciiae?e oai?eo AOAeIE
?ethno?o? oaae.1.

Oaaeeoey 1

?iciiae?e oai?eo AOAeIE ca a?eii ? noaooth

A?eO a i ? ? c A O Ae I
E(?ie?a)/ieia?eeae?ieeCaaaeiiaan.%aan.%aan.%17-292619,485,973425,3430-49
4432,842115,676548,5150 ?
noa?oa2417,91118,213526,12Caaaeii9470,15409,85134100,0

sse aeaeii c aeaieo oaae.1 AOAeIE /ano?oa cono??/a?oueny o oai?eo a?eii
a?ae 30 — 49 ?ie?a (48,51%). A?eueo?noue c oai?eo noaiiaeee /ieia?ee —
94 (70,15%). A 61 oai?iai (45,52%) aeyaeaii na?aaei?e nooi?iue aaaeeino?
caoai?thaaiiy. O?eaae?noue ae?aceiai? oai?iae 12-iaei? eeoee eieeaaeany
a?ae 1 oeaeiy aei 25 ?ie?a. Oai?? (95%) iinooiaee a noaoe?iia? a
oa?i?ie, ye? ia ia?aaeuoaaee 10 aei?a a?ae ii/aoeo oai?iae. Na?aae
ianoaaeaieo ia?aaaaeaee iaoe??ioe c o?eaae?noth caoai?thaaiiy aei 1 ?ieo
— 57 (42,54%), iniiaio e?euee?noue yeeo noaiiaeee oai?? c aia?oa
aeyaeaiith AOAeIE. Ae?aaiic anoaiiaethaaany ia i?aenoaa? nea?a,
aiae?c?a, aeaieo ia’?eoeaiiai ianoaaeaiiy. Aiaeineii?/ia aeyaeaiiy
ae?aceiaiai aeaoaeoo aoei iniiaiei ae?aaiinoe/iei e?eoa???i ?aoeeaeeao
ae?aceiai? oai?iae. I?e oeueiio i?eeiaeiny aei oaaae, ui aiaeineii?/ia
aeine?aeaeaiiy aeicaiey? a?eueo aeaoaeueii aea/eoe iai?aaeai?noue
aeeiai?ee ae?aceiaiai i?ioeano, ioe?ieoe noai ??cieo a?aeae?e?a oeoieo
oa aeaaiaaeoeyoeiaei? eeoee, a oaeiae ia?aa??eoe aoaeoeai?noue
i?iaaaeaii? oa?ai??. Noiooi? ae?acoe? ci?ie neeciai? aecia/aee
iae?ineiiiai. Na?aae aeine?aeaeoaaieo in?a ia?aaaaeaee iaoe??ioe c
aaee/eiith ae?aceiaiai aeaoaeoo a iaaeao 0,5–1,0 ni — 75 (55,97%) oa
eieae?caoe??th ae?acee ia ia?aaei?e no?ioe? 92 (68,66%). O a?eueoino?
oai?eo iaea i?noea aeaoi?iaoe?y oeeaoeeie 12-iaei? eeoee, i?e/iio ??
iayai?noue ia aoea iia’ycaia c o?eaae?noth oai?iae. Aeyaeaiiy
Helicobacter pylori (I?) a aano?iaeoiaeaiaeueieo a?iioaoao i?iaiaeeeiny
ca aeiiiiiaith De-Nol oanoo. Ia?aaaaeiei neiioiiii a on?o oai?eo aoa
aieueiaee — 91,79% oa anoaiiaaaaoaoeaiee — 63,43%. I?e ia’?eoeaiiio
ianoaaeaii? a on?o iaoe??io?a a?aei?/aeany iaeueiaoi?ii aieth/?noue a
i?iaeoe?? 12-iaei? eeoee, i?ei?ona, ai?aano?aeuei?e ae?eyioe?.
Aeine?aeaeaiiy oeoieiai? eeneioiino? i?iaiaeeeiny ca aeni?an-iaoiaeeeith
aioo??oiuei-oeoieiai? ?I–iao??? — aacaeueii? oiiia?ao?/ii? ?I–iao??? ii
i?ioyaeiino? oeoieo ca iaoiaeeeith *i?iia?iaiai ? I?aoi?ae (1989) i?e
aeiiiiic? ?iaeeeaoi?a eeneioiino? oeoieo ? ?I–i?e?iciiae?a IA–?I–2
(ae?aiao?ii 2,0 ii).

E??i aeacaieo aeua ianoaaeaiue (caaaeueiiee?i?/ieo oa
eaai?aoi?ii–?ino?oiaioaeueieo), ia 1–2 aeaiue iinooieaiiy oai?eo a
noaoe?iia? aei ii/aoeo e?eoaaiiy ? a ia??iae ianooieaiiy ?ai?n??
i?iaiaeeeiny niaoe?aeueia aeine?aeaeaiiy, iaoith yeiai aoea eiiieaenia
ioe?iea ?ioiieia?/ii? ?aaeoeaiino? o oai?eo AOAeIE. Aeey aea/aiiy
?ioiieia?/ii? ?aaeoeaiino? oai?eo aeei?enoaia iaoiaeeea A. Aaoeiai? (V.
Hashkova, 1978) o iiaeeo?eaoe?? A.A.AEaeoaay (1989, 1991). Ne?ae
aeacaoe, ui an? iieacieee ?ioiiiai noaio ianoaaeoaaieo in?a ii??aithaaee
c aeaieie, iaea?aeaieie i?e ianoaaeaii? caei?iaeo ethaeae — 50. A nai?o
aeine?aeaeaiiyo a?aea?? iaoe??io?a cae?enithaaee aac noiooi?o
caoai?thaaiue c oei, uia aeeeth/eoe aieea inoaii?o ia iieacieee, ui
aea/aeeny.

A caeaaeiino? a?ae i?iaaaeaiiai e?eoaaiiy an? oai?? AOAeIE aoee
iiae?eai? ia 4 a?oie: I a?oia — 51 oai?ee, yeei i?ecia/aeany aacenia
i?ioeae?aceiaa oa?ai?y, yea aeeth/aea ae??oo ? 1, aeieaoi?e i?ioiiiai?
iiiie (iiai?acie ii 20 ia 2 ?ace a aeaiue), aioeoae?eiaaeoa?io oa?ai?th
(o?eoiiie ii 250 ia 4 ?ace a aeaiue aai aii?oeee?i 500 ia 4 ?ace a
aeaiue) oa i?aia?aoe a?niooo (aea-iie ii 120 ia 4 ?ace a aeaiue); II
a?oia — 25 oai?eo AOAeIE, ye? e??i aeua aeacaii? aacenii? oa?ai??
io?eioaaee ianoieeo ao?iaoea? io?io?ii? ii 15 e?aiaeue 3 ?ace a aeaiue
12 aei?a; III a?oia — 35 oai?eo AOAeIE, ye? io?eioaaee aacenio oa?ai?th
a ii?aeiaii? c ianoieeith ao?iaoea? io?io?ii? o aeua aeacai?e aeic? oa
a?oai?iii A (-oieioa?ieii aoeaoaoii) ii 100 ia 1 ?ac a aeaiue i?ioyaii
12 aei?a; IV a?oia — 23 oai?eo AOAeIE, ye? io?eioaaee aacenio oa?ai?th a
ii?aeiaii? c -oieioa?ieii aoeaoaoii o aeua aeacai?e aeic?.

Noaoenoe/ia ia?iaea io?eiaieo aeaieo aeeiiaia ia ia?niiaeueiiio
eiii’thoa?? c aeei?enoaiiyi noaiaea?oieo iaeao?a i?ia?ai Microsoft Word,
6.0.

?acoeueoaoe aeine?aeaeaiue.

Ie i?iaaee ee?i?ei-?ioiieia?/iee aiae?c oai?eo AOAeIE a caeaaeiino? a?ae
oei?a iaaaeii? a?ia?/ooeeaino? (IA*) ii Geels, Coombs, a?eo, o?eaaeino?
oa aaaeeino? caoai?thaaiiy ? aaee/eie ae?aceiaiai aeaoaeoo.

Oaaeeoey 2

?acoeueoaoe ?ioiieia?/ieo aeine?aeaeaiue iaoe??io?a AOAeIE

Oe?E

o.i.O?E

o.i.NNO

o.i.???

o.i.Eiio?ieue

n=5012,50 1,1517,20 1,504,70 0,702,70 0,20AO AeIE

n=13418,92 0,5730,08 0,86

11,18 0,46

1,73 0,07

P< 0,001< 0,001< 0,001< 0,001 Aea/aiiy ?ioiiiai noaio o oai?eo AOAeIE aeicaieeei anoaiiaeoe iayai?noue ?ioiieia?/iiai aeenaaeaino, ui oa?aeoa?eco?oueny ca?eueoaiiyi iieaciee?a Oe?E, O?E, NNO oa ??? (?< 0,001). Iiae?ai? ca?eueoaiiy ai?noo Oe?E ? O?E na?ae/aoue i?i ae?aaeaio aeoeai?noue iaoieia?/iiai i?ioeano. A ciaioaiiy ??? i?i aeai?an?th eiiia?aoe?? i?ae A-e?ioioeeoaie oa O-oaeia?aie. O 89 (66,4% ) oai?eo eiinoaoiaaii 2 oei iaaaeii? a?ia?/ooeeaino? ii Gell? Coombs, ui aeaco? ia oa, ui a ae?th anooiathoue o?eniaai? ?ioii? eiiieaene, ui i?aeoaa?aeaeo?oueny aeinoia??iei (?<0,001) i?aeaeuaiiyi iieaciee?a Oe?E, O?E a ii??aiyii? c iieacieeaie o caei?iaeo ethaeae. Aea i?e ianoaaeaii? ?ioiii? nenoaie aeyaeaii oaeiae 1 oa 3 oeie IA*. I/aaeaeii, ooo a?ae?a?a? naith ?ieue HP, yeee ? iaeiei c i?ia?aeieo oaeoi??a ae?aceiooai?aiiy. I?e aiae?c? ?ioiiiai noaio oai?eo aeyaeaii caeiiii??iino? o?eueee a caeaaeiino? a?ae nooiaiy aaaeeino? i?io?eaiiy AOAeIE. A 52 iaoe??io?a, ui noaiiaeoue 38,81% aeyaeaii eaaeee nooi?iue aaaeeino? i?io?eaiiy AOAeIE. A iniiaiiio oea aoee oai?? c aia?oa aeyaeaiith AOAeIE. O oai?eo c eaaeei nooiaiai aaaeeino? ci?ie ?ioiieia?/ieo iieaciee?a iaio ae?aaeai? Oe?E 21,20,51 o.i., O?E 32,11±0,21 o.i., NNO 9,91±0,39 o.i., ??? 2,14±0,14 o.i., a o oai?eo c aaaeeei ia?aa?aii aeyaeaii a?eueo aeeaie? ci?ie: ??? 1,39±0,1 o.i. (? 0,001), ui a?aeia?aaea? iiaeeaeaiiy ?ioiii? aeai?an??, Oe?E 17,07±0,52o.i. (? 0,001) oa O?E 29,35±0,11 o.i. (? 0,001) ciaioothoueny ?c nooiaiai aaaeeino? AOAeIE. I?e eaaeiio nooiai? aaaeeino? AOAeIE ?ioii? eiiieaene ciaoiaeyoueny ia?aaaaeii a oee?eoethth/iio noai?. C iiaeeaeaiiyi aaaeeino? i?io?eaiiy e?euee?noue ?ioiieo eiiieaen?a, i/aaeaeii, caycaia c a?eueo aeeaieeie oa?aie ee?oei, ui iiaea aeacoaaoe ia ?o ciaioaiiy c 21,20,51 o.i. aei 17,07±0,52 o.i. (?0,001). Ciaioaiiy ??? a 1,5 ?aca c aaaee?noth caoai?thaaiiy a?aeaoaa?oueny ca ?aooiie O-oaeia?ii? aeai?an??, ? ii?aeio?oueny c aeine?aeaeaiiyie ?ioeo aaoi??a (A/eiaa I.A. e niaao., 1993). I?e aiae?c? ?ioiieia?/ieo iieaciee?a o oai?eo a caeaaeiino? a?ae o?eaaeino? caoai?thaaiiy, a?eo oa aaee/eie ae?aceiaiai aeaoaeoo caeiiii??iino? ia niinoa??aaeeny. O oai?eo, a caeaaeiino? a?ae o?eaaeino? caoai?thaaiiy, aeyaeaii o?eueee aeinoia??ia ciaioaiiy ???, yeee noaiiaea 1,32±0,08 o.i. (?0,001) o iaoe??io?a c o?eaae?noth AOAeIE a?eueoa 10 ?ie?a ? aoa a aeaa ?ace ieae/ei ca aeai? o caei?iaeo in?a. ?acoeueoaoe iaoeo aeine?aeaeaiue i?aeoaa?aeaeothoue aeai? ?ioeo aaoi??a (A/eiaa I.A. e niaao., 1992; Iaeia TH.N., 1990). I?e ioe?ioe? ?ioiieia?/ieo iieaciee?a a caeaaeiino? a?ae a?eo iaoe??io?a aeyaeaii iaea?eueo nooo?a? ci?ie o oai?eo a?eii 30—49 ?ie?a: Oe?E 17,92±0,61 o.i. (?0,05), O?E 28,75±0,73 o.i. (?0,05) oa ??? 1,64±0,04 o.i. (?0,01) a ii??aiyii? c ?ioiieia?/ieie iieacieeaie o iaoe??io?a a?eii a?ae 17 aei 29 ?ie?a. Iaoe??ioe aeaii? a?eiai? a?oie iae/ano?oa oai??thoue AOAeIE. Oea iiaeia iiynieoe ie?aiith iaoiaaiaoe/iith eaieith o?ii?caoe?? iaoieia?/iiai i?ioeano ? eiai eiie?aoiei i?iyaii. O oai?eo AOAeIE c ae?aceiaei aeaoaeoii a?eueoa 1 ni a ii??aiyii? c oai?eie, o yeeo ae?acea aoea aei 0,5 ni, aeyaeaii aeinoia??ia ciaioaiiy iieacieea ??? 1,57±0,08 o.i. (?0,01) a oie /an, ye Oe?E oa O?E ciaioeeeny, aea ??cieoey ? iaaeinoia??iith. I?e i?iaaaeaii? De-Nol-oanoo aeyaeaia i?enooi?noueHelicobacter pylori a 128 (95,52%) iaoe??io?a. Ca aeaieie ?I-iao??? niinoa??aaeiny i?aeaeuaiiy eeneioiooai?thth/i? ooieoe?? oeoieo a 92 (68,66%) oai?eo oa a 29 (21,64%) —ii?iioeeaei?noue. Oaeei /eiii, aeyaeaiee ?ioiieia?/iee aeenaaeain aeaco? ia aaaeeeao iaoiaaiaoe/io ?ieue ?ioii?aaoeyoi?ieo i?ioean?a AOAeIE ? aeicaiey? aianoe ei?aeoeae a ?? oa?ai?th. Oiio ie aaaaeaee iaiao?aeiei aeei?enoaoe i?aia?aoe c ?ioiiiiaeoethth/ith ae??th a eiiieaen? c o?aaeeoe?eiith oa?iaeioa?ai??th. Aeine?aeaeaiiy c canoinoaaiiyi aacenii? oa?ai?? iieacaei aenieo ?? ee?i?/io aoaeoeai?noue. I?ae aieeaii o?aaeeoe?eii? oa?ai?? o oai?eo ia 5 aeaiue cieeaee i?iyae aieueiaiai oa ia 6 aeaiue aeeniaioe/iiai neiae?ii?a. Anoaiiaaaaoaoeaiee neiae?ii caa??aaany, ii?iae?coaaeany oeoieiaa nae?aoe?y. Ii?yae c oeei aeinoia??ia ciaioaiiy iieaciee?a Oe?E 15,5±0,53 o.i. (?<0,001), O?E 27,0±0,81 o.i. (?<0,001), oa ??? 1,42±0,06 o.i. (?<0,001) ia oii? iaaeinoia??iiai ca?eueoaiiy NNO 11,49±0,4 o.i. (?>0,05), i?ney e?eoaaiiy aeacothoue ia iaaeinoaoith
?ioiieia?/io ei?aeoe?th. Iacaaaeath/e ia oa, ui i?ney e?eoaaiiy Oe?E aoa
iaaeeaeaiee aei ii?ie (N– 12,5±1,15 o.i.), ?aooa iieaciee?a
i?aeoaa?aeaeoaaee iayai?noue ?ioiieia?/iiai aeenaaeaino, yeee ? iaeiei
?c oaeoi??a, ui ni?eythoue i?aeo?eiaiith iaoieia?/iiai i?ioeano a
aano?iaeoiaeaiaeuei?e cii?.

Ioaea, iaaeinoaoiy aoaeoeai?noue caaaeueiii?eeiyoi? oa?iaeioa?ai??
ae?aceiai? oai?iae 12-iaei? eeoee aeeeoo? iaiao?aei?noue aeei?enoaiiy
i?aia?ao?a, ye? aeicaieeee a iie?aueoe iieacieee ?ioiii? nenoaie o
ooieoe?iiaeueiiio ieai? iacaeaaeii a?ae oiai, aoee aiie cieaeai? /e
i?aeaeuai?. A yeino? oaeeo i?aia?ao?a aoei canoiniaaii ianoieeo
ao?iaoea? io?io?ii? oa a?oai?i E.

I?e i?iaaaeaii? aacenii? oa?ai?? a ii?aeiaii? c ianoieeith ao?iaoea?
io?io?ii?, a?aei?/aii ca?eueoaiiy ai?noo a ne?iaaooe? e?ia? Oe?E c
19,16± 0,46 o.i. — 24,24±0,51 o.i. (?<0,001), O?E c 30,48±0,92 o.i. — 36,16±0,66 o.i. (?<0,001), ??? c 1,79±0,09 o.i. —2,19±0,06 o.i. (?0,001). I/aaeaeii, ui ca?eueoaiiy Oe?E a?aeaoaa?oueny ca ?aooiie aea?eueiaiiy o?eniaaieo ?ioiieo eiiieaen?a c oeaiei ?, ye? i?ney e?eoaaiiy, ia?aoiaeyoue a Oe?E. Ca?eueoaiiy ??? i?ney e?eoaaiiy eiinoaoiaaii a oaeeo i?aea?oiao: o oai?eo a?eii 30–49 ?ie?a 2,29±0,12 o.i. (?<0,05) oa 50–65 ?ie?a — 2,31±0,09 o.i. (?<0,05); c o?eaae?noth caoai?thaaiiy aei iaeiiai ?ieo — 2,4±0,13 o.i. (?<0,001), oa a?eueoa 10 ?ie?a 2,23±0,14 o.i. (?<0,05); c eaaeei nooiaiai aaaeeino? i?io?eaiiy AOAeIE — 2,46±0,09 o.i. (?<0,05); oa aaee/eiith ae?aceiaiai aeaoaeoo aei 0,5 ni — 3,25±0,18 o.i. (?<0,001) i?e iaeiaeiaeo Oe?E oa O?E a ne?iaaooe? e?ia?. Aeua aeacaia oa?iaeioa?ai?y ia o?eueee iie?auo? ?ioiiee noai i?aai?cio, aea e ni?ey? ciaioaiith ?aoeeaeea?a AOAeIE ia 14% o ii??aiyii? c aaceniith oa?ai??th c oa?i?iaie caai?iiy ae?acee o iaio aeine?aeaeoaaieo a?oiao — 80% /a?ac o?e oeaei?. I?e aeei?enoaii? aacenii? oa?ai?? iaeii/anii c ianoieeith ao?iaoea? io?io?ii? oa a?oai?iii A, niinoa??aa?oueny ca?eueoaiiy iieaciee?a Oe?E 28,34±0,36 o.i., O?E 40,34±0,56 o.i., NNO 12,00±0,32 o.i. oa ??? 2,39± 0,05 o.i. I?e oeueiio (?<0,001) aeey an?o iieaciee?a. Oaiaeaioe?y aei ii?iae?caoe?? ??? niinoa??aa?oueny o an?o a?eiaeo a?oiao iaoe??io?a AOAeIE c iaeii/aniei a??ia?aeiei ca?eueoaiiyi ?aooe iieaciee?a i?ney e?eoaaiiy. Ca?eueoaiiy Oe?E ? O?E o ne?iaaooe? oai?eo oa ??? a?aei?/a?oueny o oai?eo c o?eaae?noth caoai?thaaiiy aei 1 ?ieo oa a?ae 1–5 ?ie?a ? o oai?eo c eaaeei oa na?aaei?i nooiaiai aaaeeino? AOAeIE. I?e/iio iieaciee ??? aoa iaaeeaeaiei aei ii?ie o oeeo a?oiao iaoe??io?a. Oaae naia ie a?aei?/aee o oai?eo AOAeIE iacaeaaeii a?ae aaee/eie ae?aceiaiai aeaoaeoo. Ii?yae c iie?auaiiyi ?ioiieia?/ieo iieaciee?a a aeai?e a?oi? aeyaeai? iiceoeai? ci?ie c? noi?iie ee?i?/ieo i?iya?a: ciaioaiiy aieueiaiai (3–4 aeaiue) oa aeeniaioe/iiai (2–3 aeaiue) neiae?ii?a, a iniaeeai anoaiiaaaaoaoeaiiai neiae?iio, ui ci?ia? aaaee?noue i?iya?a iniiaieo neiioii?a caoai?thaaiiy; nei?i/aiiy oa?i?i?a caai?iiy ae?acee 94,29% aeiaaee?a a ii??aiyii? c oai?eie, ui io?eioaaee aacenio oa?ai?th — 80,39%. Aeaia e?eoaaiiy aeaei ciiao caaacia/eoe a?eueo no?eeo ? o?eaaeo ee?i?ei-aiaeineii?/io ?ai?n?th a 79,29% iaoe??io?a, i?ioe 94,12% — i?e aaceni?e oa?ai??. Aeei?enoaiiy a?oai?io E a aeicao 100 ia iaeei ?ac a aeaiue a ii?aeiaii? c aaceniith oa?ai??th aeaco? ia aeinoia??ia ciaioaiiy an?o ?ioiieia?/ieo iieaciee?a: Oe?E 10,48±0,49 o.i. (?<0,001), O?E 20,43±1,29 o.i. (?<0,01), NNO 9,96±0,51 o.i. (?<0,05), ??? 1,11±0,08 o.i. (?<0,001). I/aaeaeii, aeei?enoaiiy a?oai?io A o aeacaieo aeicao i?eaiaeeoue aei iineeaiiy ae?? aacenii? oa?ai??. Oaeei /eiii, o?eueee ii?aeiaia aeei?enoaiiy i?e AOAeIE aacenii? oa?ai?? c a?oai?iii E ? ianoieeith ao?iaoea? io?io?ii?, ia iaoo aeoieo, aeinoia??ii aoaeoeai?oa, i?ae aeei?enoaiiy eiaeiiai c oeeo i?aia?ao?a ie?aii, ui i?aeoaa?aeaeothoue aeai? ?ioiieia?/ieo iieaciee?a, ye ?acoeueoao iineeaiiy ?ioiii? a?aeiia?ae? i?aai?cio. I?aeaeuaiiy Oe?E i?e AOAeIE iiaeia aaaaeaoe caoeniith ?aaeoe??th, yea iia?e?co? ai?oae?coth/? aeanoeaino? ee?oei i?aai?cio, ui i?aeoaa?aeaeo?oueny aeaieie ?yaeo aaoi??a (Aeaianueeee A.I. ? ni?aaao., 1992; Begum S. et al., 1992). Aeeth/aiiy ?ioiiei?aaoth/eo i?aia?ao?a a eiiieaenio oa?ai?th oai?eo ae?aceiaith oai?iaith 12-iaei? eeoee c ?ioiieie ii?ooaiiyie, caaacia/o? oaeiae i?io?eaeoeeo ee?i?/ieo oneeaaeiaiue, ia??aeei iaoiiaeaieo naia ci?iaie ?ioi?oaoo. Ioaea, caaaeyee nai?e aoaeoeaiino? ianoieea ao?iaoea? io?io?ii? oa a?oai?i E iiaeooue noaoe aeiiiaiaiiyi aei ?nioth/iai a?naiaeo i?ioeae?aceiaeo e?ea?nueeeo cania?a. AENIIAEE 1. Caaino?aiiy ae?aceiai? oai?iae 12-iaei? eeoee oa?aeoa?eco?oueny ?ioiieia?/iei aeenaaeainii, ui i?iyaey?oueny ia o?eueee cieaeaiiyi ?ioii?aaoeyoi?iiai ?iaeaeno oa i?aeaeuaiiyi ??aiy oee?eoethth/eo ?ioiieo eiiieaen?a, aea e i?aeaeuaiiyi ai?noo oieiaeiaeo ?ioiieo eiiieaen?a a ne?iaaooe? e?ia?. 2. Ci?ie ?ioiieia?/iiai iii?oi?eiao ia caeaaeaoue a?ae o?eaaeino? caoai?thaaiiy, a?eo, aaee/eie ae?aceiaiai aeaoaeoo ? ci?iththoueny a caeaaeiino? a?ae nooiaiy aaaeeino? i?io?eaiiy AOAeIE: /ei aaae/ee ia?aa?a, oei ieae/? iieacieee ?ioii?aaoeyoi?iiai ?iaeaeno, oee?eoethth/? oa oieiaeia? ?ioii? eiiieaene. 3. Aacenia i?ioeae?aceiaa oa?ai?y ia onoaa? iiai?noth ?ioiieia?/i? ii?ooaiiy, ui ? iaeiei ?c oaeoi??a ?eceeo ?aoeeaeeaoaaiiy ? aeaeueoiai i?ia?anoaaiiy caoai?thaaiiy. 4. Aeyaeaiiy ?ioiieia?/iiai aeenaaeaino ? iieacaiiyi aeey aeeth/aiiy a eiiieaen i?ioeae?aceiai? oa?ai?? i?aia?ao?a c ?ioiiei?aaoth/ei aieeaii, cie?aia, ao?iaoea? io?io?ii?, ui ni?ey? iie?auaiith ?ioiieia?/ieo iieaciee?a, aea ia aeinyaa?oueny ii?iae?caoe?? ?o. 5. Ii?aeiaia canoinoaaiiy eiiieaenii? oa?ai?? c aeeth/aiiyi ianoieee ao?iaoea? io?io?ii? oa a?oai?io A (-oieioa?ieo aoeaoaoo) a e?eoaaii? ?aoeeaeea?a ae?aceiai? oai?iae 12-iaei? eeoee ni?ey? ii?iae?caoe?? ee?i?ei-?ioiieia?/ieo iieaciee?a, aeinyaiaiith no?eei? ee?i?ei-aiaeineii?/ii? ?ai?n?? oa ciaioaiith /anoioe ?aoeeaeea?a caoai?thaaiiy. I?AEOE*I? ?AEIIAIAeAOe?? 1. A eiiieaeni?e ae?aaiinoeoe? oai?eo ae?aceiaith oai?iaith 12-iaei? eeoee aeioe?eueii aeei?enoiaoaaoe ne?ei?iaia? ?ioiieia?/i? aeine?aeaeaiiy c iaoith ioe?iee ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio. 2. I?e iayaiino? ?ioiieia?/iiai aeenaaeaino o oai?eo AOAeIE iaiao?aeii aeeth/aoe a eiiieaen i?ioeae?aceiai? oa?ai?? ?ioiiei?aaoth/? i?aia?aoe. 3. A?aoiaoth/e, ui iaea?eueo nooo?aee ?ioiieia?/iee aeenaaeain niinoa??aa?oueny o oai?eo c aaaeeei ia?aa?aii AOAeIE, canoinoaaiiy ?ioiiei?aaoth/i? oa?ai?? o aeaieo oai?eo ? iaia’yceiaei. 4. Aeeth/aiiy a eiiieaenio oa?ai?th ianoieee ao?iaoea? io?io?ii? ii 15 e?aiaeue o?e ?ace a aeaiue i?ioyaii 12 aei?a oa -oieioa?ieo aoeaoaoo ii 1 eainoe? (100 ia) iaeei ?ac a aeaiue i?ioyaii 12 aei?a ni?ey? ii?iae?caoe?? ee?i?/ieo oa ?ioiieia?/ieo ii?ooaiue, aeinyaiaiith no?eei? aiaeineii?/ii? ?ai?n?? oa i?io?eaeoeoe? ?aoeeaeea?a AOAeIE. NIENIE IIOAE?EIAAIEO ?IA?O II OAI? AeENA?OAOe?? 1. Iieacieee ?ioiiiai noaio i?e eiiieaeniiio e?eoaaii? oai?eo ia ae?aceiao oai?iao aeaaiaaeoeyoeiaei? eeoee / Aeooea ?.ss., Iaoo- uae I.I., Aaeueia? C.A., Eaiiaaoeue E.?. // E?ea?nueea ni?aaa=A?a/aaiia aeaei.— 1998.— 3.— N. 96-98. 2. Iaoouae I.I. Ee?i?ei-?ioiieia?/i? iniaeeaino? ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee // I?aeoe/ia iaaeeoeeia.— 1998.— ? 7-8.— N. 34-36. 3. Iaoouae I.I. Aeei?enoaiiy ao?iaoea? io?io?ii? a e?eoaaii? ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee // I?aeoe/ia iaaeeoeeia.— 1999.— ? 1- 2.— N. 98-99. 4. Iaoouae I.I. Aioaoeeaei? caniae a e?eoaaii? ae?aceiai? oai?iae (no/ani? aeai?) // I?aeoe/ia iaaeeoeeia.— 1998.— ? 3-4.— N.111-114. 5. Iaoouae I.I., Aeooea ?.ss. ?ioiiiiaeoethth/a oa?ai?y i?e ae?aceia?e oai?ia? aeaaiaaeoeyoeiaei? eeoee // 14 c’?cae oa?aiaao?a Oe?a?ie: Iaoa??aee.— Ee?a, 1998.— N.387-388. 6. Zseltvay Viktor, Matuschak Olga The effect of tincturae echinacea purpurea on the function of immune system by ulcus duodeni // Science, Technology, Development.— Uzhgorod, 1998.— P. 129. 7. Zseltvay Viktor, Matuscsak Olga, Pinter Ferenc A tinctura echinaceae es a bionet balzam hatasa a nyombelfekelyes betegek immunologiai mutatoira // A Magyar Tudomanyos Akademia Szaboles — Szatmar-Bereg Megyei Tudomanyos Testuletenek 1998. szeptember 25-iki kerekasztal — konferenciajan es szeptember 26-iki tudomanyos ulesen elhangzott.— Nyiregyhaza, 1998.— P.126. 8. ?acoeueoaoe e?eoaaiiy ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee (AOAeIE) iiai?acieii oa ?ai?o?ae?iii / Aeooea ?.ss., Aaeueia? C.A., Aaa?eethe C.I., Iiainaae A.A., Oaeueei ?.A., Iaoouae I.I., Neiai-aea I.?. // Aeooaeuei? i?iaeaie iaaee/iiai ianeoaiaoaaiiy i?aoethth/eo ia cae?cie/iiio o?ainii?o?: Iaoa??aee eiioa?aioe??.— Oaeai?iae, 1996.— N.112-113. AIIOAOe?ss Iaoouae I.I. Ee?i?ei-?ioiieia?/i? iniaeeaino? ae?aceiai? oai?iae aeaaiaaeoeyoeiaei? eeoee i?e eiiieaeni?e oa?ai?? c aeeth/aiiyi a?oai?io A oa ao?iaoea? io?io?ii?.— ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02 –Aioo??oi? oai?iae.– ?aaii-O?aie?anueea aea?aeaaia iaaee/ia aeaaeai?y, i. ?aaii-O?aie?anuee, 1999 ?. Aeena?oaoe?y i?enay/aia aea/aiith ee?i?ei-?ioiieia?/ieo ci?i o oai?eo AOAeIE, ?o ei?aeoe?? ca aeiiiiiaith ?ioiiiiaeoeyoi?a ?ineeiiiai iioiaeaeaiiy — ao?iaoea? io?io?ii? oa a?oai?ia A. Anoaiiaeaii, ui iaea?eueo aoaeoeaiei ? ii?aeiaiiy aacenii? oa?ai?? c aeaiia i?aia?aoaie ?ioiiei?aaoth/i? ae??, ui i?eaiaeeoue aei iie?auaiiy ?ioiieia?/ieo iieaciee?a, nei?i/aiiy oa?i?i?a noaoe?iia?iiai e?eoaaiiy ? iiaeiaaeaiiy ?ai?n??. Cai?iiiiiaaii aeei?enoaiiy iaoiaeo ?ioiieia?/iiai ne?ei?iao a yeino? aeinooiiiai ? ?ioi?iaoeaiiai iaoiaeo ae?aaiinoeee ?ioiiiai noaio oai?eo AOAeIE. Eeth/ia? neiaa: ae?aceiaa oai?iaa aeaaiaaeoeyoeiaei? eeoee, ?ioiiee noai, eiiieaenia oa?ai?y, ?ioiiiiaeoethth/a oa?ai?y, ao?iaoeay io?io?ia, a?oai?i A. AIIIOAOeEss Iaoouae I.I. Eeeieei-eiioiieiae/aneea iniaaiiinoe ycaaiiie aieacie aeaaiaaeoeaoeia?noiie eeoee a eiiieaeniie oa?aiee n aeeth/aieai aeoaieia A e oeiaoeee io?io?iie.— ?oeiienue. Aeenna?oaoeey ia nieneaiea o/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02 –Aioo?aiiea aieacie.– Eaaii-O?aieianeay ainoaea?noaaiiay iaaeeoeeineay aeaaeaiey, a. Eaaii-O?aieiane, 1999. Caueuaaony aeenna?oaoeey, ii iaoa?eaeai eioi?ie iioaeeeiaaii 8 iao/io ?aaio, a eioi?uo aeieacaia yooaeoeaiinoue eiiieaeniiai ea/aiey n eniieueciaaieai i?aia?aoia, aeeythueo ia eiioiioth nenoaio aieueiuo n ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. A ?aaioa aiaeece?othony aeaiiua, iieo/aiiua a ?acoeueoaoa ianeaaeiaaiey 134 aieueiuo n ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee a noaaeee iaino?aiey e 50 iaoeeaioia — i?aeoe/anee caei?iauo ethaeae. Anai iaoeeaioai i?iaiaeeeinue eiiieaeniia ianeaaeiaaiea iauaeeeie/aneia e eaai?aoi?ii-eino?oiaioaeueiia, eioi?ia aeeth/aei: ycioaaioea?iaano?iaeoiaeaiineiieth (OAeAN), auyaeaiea Helicobacter pylori (HP) a aano?iaeoiaeaiaeueiuo aeiioaoao, enneaaeiaaiea aeaeoaei/iie eeneioiinoe n iiiiuueth yeni?ann-iaoiaeeee aioo?eaeaeoaei/iie ?I-iao?ee, enneaaeiaaiea eiioiieiae/aneiai noaoona. Eco/aiea eiioiieiae/aneie ?aaeoeaiinoe aeaiiai eiioeiaaioa aieueiuo iicaieeei onoaiiaeoue iaee/ea eiioiieiae/aneiai aeenaaeaina, eioi?ue oa?aeoa?ecoaony ?aciiiai?aaeaiiuie eciaiaieyie iieacaoaeae eiioii?aaeoeaiinoe i?aaiecia, a /anoiinoe, ieceei iieacaoaeai eiioii?aaoeyoi?iiai eiaeaena e aunieei o?iaiai oee?eoee?othueo eiioiiuo eiiieaenia e oieiaeiauo eiioiiuo eiiieaenia. N iiiiuueth iaoiaea eiioiieiae/aneiai ne?eieiaa auyaeaii o?e oeia iaiaaeeaiiie aeia?/oanoaeoaeueiinoe (IA*) e caeiiiia?iinoe a caaeneiinoe io noaiaie oyaeanoe ycaaiiie aieacie 12-ia?noiie eeoee: /ai oyaeaeaa oa/aiea aieacie, oai ieaea iieacaoaee eiioii?aaoeyoi?iiai eiaeaena, oee?eoee?othueo e oieiaeiao eiioiiuo eiiieaenia. O?aaeeoeeiiiay i?ioeaiycaaiiay oa?aiey ia iieiinoueth ei??aae?oao eiioiieiae/aneea ia?ooaiey, /oi a aeaeueiaeoai i?eaiaeeo e ?aoeeaeeao e i?ia?anne?iaaieth aieacie. Aeyaeaiea eiioiieiae/aneiai aeenaaeaina neoaeeo iieacaieai aeey aeeth/aiey a eiiieaen i?ioeaiycaaiiie oa?aiee i?aia?aoia n eiioiiei??aae?othuei aeaenoaeai. Onoaiiaeaii, /oi iaeaieaa yooaeoeaii ni/aoaiea aaceniie oa?aiee n aeaoiy eiioiiei??aae?othueie i?aia?aoaie. Eniieueciaaiea eiioiiiiaeoeyoi?a ?anoeoaeueiiai i?ienoiaeaeaiey — yoeiaoeae io?io?iie e aeoaieia A — i?eaiaeeo e au?aaeaiiie ei??aeoeee eiioiieiae/aneeo iieacaoaeae, niinianoaoao nie?auaieth n?ieia noaoeeiia?iiai ea/aiey e oaeeeiaieth ?aiennee caaieaaaiey. I?aaeeiaeaii eniieueciaaiea iaoiaea eiioiieiae/aneiai ne?eieiaa a ea/anoaa aeinooiiiai e eioi?iaoeaiiai iaoiaea aeeaaiinoeee eiioiieiae/aneiai ninoiyiey aieueiuo ycaaiiie aieaciueth aeaaiaaeoeaoeia?noiie eeoee. Eeth/aaua neiaa: ycaaiiay aieaciue aeaaiaaeoeaoeia?noiie eeoee, eiioiieiae/aneia ninoiyiea, eiiieaeniay oa?aiey, eiioiiiiaeoee?othuay oa?aiey, yoeiaoeay io?io?iay, aeoaiei A. SUMMARY Matuschak O.M. Clinico-immunological pecularities of duodenal ulcer in complex therapy with involvement of vitamin E and echinacea purpurea.— Manuscript. Dissertation for competition of getting the scientific degree of the candidate of the medical sciences, speciality 14.01.02 –Internal diseases.– Ivano-Frankivsk State Medical Academy, Ivano-Frankivsk, 1999. The dissertation is devoted to the study of clinico-immunological changes in patients with duodenal ulcer, their correction with the help of immunomodulator of plant origin — Echinacea purpurea and vitamin E. It was estimated, that most effective is the combination of basic therapy with two preparations of immunocorregating action, what leads to improvement of immunological indeces, shortening of terms of stationary treatment and lengthening of remission. Proposed was the use of immunological screening method as accessible and informative method of diagnostics of immune state of duodenal ulcer patients. Key words: duodenal ulcer, immune state, complex therapy, immunomodulating therapy, Echinacea purpurea, vitamin E.

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