Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao

OAeE 616.33-002.44-08:616- 002.7

Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao

Aia?iaa A.?

ee?ie/ia cia/ou?noue aea/aiiy a?ioeaiico oianoi? eeoee i?e o?ii?/ieo
aae?eiaaeoa?-anioe?eiaaieo caoai?thaaiiyo i?aai?a aano?iaeoiaeaiaeueii?
ciie o ae?oae

14.01.10 — iaae?ao??y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeao iaaee/ieo iaoe

Oa?e?a — 2000

Aeena?oaoe??th ? ?oeiien

?iaioo aeeiiaii a Oa?e?anuee?e iaaee/i?e aeaaeai??

i?neyaeeieiiii? ina?oe IIC Oe?a?ie

Iaoeiaee caneoaeaiee ae?y/ iaoee ? oaoi?ee Oe?a?ie, aeieoi?
iaaee/ieo iaoe,

ea??aiee: : i?ioani? A?eionia TH??e Aieiaeeie?iae/, Oa?e?anueea

iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe, caa?aeoth/ee

eaoaae?ith aeeoy/i? aano?iaioa?ieia??.

Io?oe?ei? aeieoi? iaaee/ieo iaoe, i?ioani?

iiiiaioe: Iaeeiaoeue TH??e Aaneeueiae/, Oa?e?anueeee aea?aeaaiee

iaaee/iee oi?aa?neoao, caa?aeoth/ee eaoaae?ith

oaeoeueoaonueei? iaae?ao??? c iaaee/iith aaiaoeeith.

aeieoi? iaaee/ieo iaoe, i?ioani?

Ia?oiiaiei Ethaeieea Einoyioei?aia, Oa?e?anueea iaaee/ia

aeaaeai?y i?neyaeeieiiii? ina?oe, caa?aeoaa/ea eaoaae?ith

oa?ai?? i?aee?oeiaiai a?eo.

I?ia?aeia onoaiiaa: ?inoeooo iaae?ao???, aeooa?noaa oa a?iaeieia?? AII
Oe?a?ie, i. Ee?a, a?aeae?e aano?iaioa?ieia??.

Caoeno a?aeaoaeaoueny “23” aa?aciy 2000 ?ieo i 14 aiaeei?

ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae.64.600.04 i?e
Oa?e?anueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? ca aae?anith: 61022,
i. Oa?e?a,

i?iniaeo Eai?ia, 4.

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai

iaaee/iiai oi?aa?neoaoo ca aae?anith: 61022, i. Oa?e?a, i?iniaeo Eai?ia,
4.

Aaoi?aoa?ao ?ic?neaiee “20” ethoiai 2000 ?ieo.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
Ia/a?aiei E.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. O no?oeoo?? o?ii?/ieo caoai?thaaiue i?aai?a nenoaie
o?aaeaiiy o ae?oae aaaeo/a i?noea (60-70%) caeiathoue o?ii?/i?
caoai?thaaiiy aano?iaeoiaeaiaeueii? ciie /Aa?aiia A.E., Ee?iainueea
A.A., 1995; Iaeeia A.E., 1996; Cai?oaeiia A.I., 1998/.

?ioa?an aei aea/aiiy o?ii?/ieo caoai?thaaiue oeoiea ? AeIE cia/ii c??n a
inoaii? ?iee c a?aee?eooyi ?ie? a ?o ?icaeoeo i?e?ia?a ?iaeo
Helicobacter /Ua?aaeia I.E., O?e?i A.A., Iaco??i E.I., 1997;
Ei?noinueeee A., 1998; Cae??ia I.C., 1998; Marhall B.J., 1989; Goodwin
C.S., Mendall M.M., 1997/.

A aeaiee /an ia aeeeeea? noii?ao, ui H? ? ao?ieia?/iei /eiieeii o
80-85% aeiaaeeao o?ii?/iiai aano?eoo ? aano?iaeoiaeai?oo, a?eueo i?ae o
95% oai?eo, ui no?aaeaeathoue AO AeIE, 70-80% oai?eo AOO /Caoa?ia E.A.,
Oa?ania A.I., Eenaiei A.A., 1996; Iaco??i A.A. ? ni?aaao., 1996; Oaoe
?.A., I?io?aa O.I., Aii/a? I.A., 1997; Aeaieniaa A.I., 1998; Kuipers
E.J., Thijs J.C., 1995/.

Aeciaiiy ao?ieia?/ii? ?ie? I? aenoioei ia ia?oee ieai ieoaiiy nai?/anii?
ae?aaiinoeee aae?eiaaeoa?ii? ?ioaeoe?? ? ao?io?iiii? ?? oa?ai??. Ieoaiiy
ae?aaiinoeee aae?eiaaeoa?ii? ?ioaeoe?? a aeaiee /an ?ic?iaeai?
aeinoaoiuei aeia?a /Iaeeia A.E., ?aaiia A.A., 1997; I?ia?a
A.?.,Iana?aeneee TH.A., Ai?iaueia A.A., 1997; *oeia N.C. ? ni?aaao.,
1998; Vazquez M.A., Valle J., 1997/.

Ieoaiiy aaeaeaaoii? oa?ai?? aae?eiaaeoa?ii? ?ioaeoe?? o ae?oae, ye ?
?ai?oa, caeeoathoueny aeooaeueieie. Aeey e?eoaaiiy aano?iaioa?ieia?/ii?
iaoieia??, anioe?eiaaii? c aae?eiaaeoa?iith ?ioaeoe??th, iaiao?aeia
aeei?enoaiiy niaoeeo?/ii? aioeaaeoa??aeueii? oa?ai??, yea iiaeiia
aoaeoeaii aieeaaoe ia I?.

A aeaiee /an oea aeinyaa?oueny aeei?enoaiiyi oae caaii? iio??eii? aai
eaaae?ioa?ai??, ui aeeth/a? i?aia?aoe a?niooo, iao?ii?aeacieo, o
niieo/aii? c aioeaaeoa??aeueiith /oeaiienei, aiieneoeee?i / oa?ai??th ?
i?aia?aoaie c a?oie aeieaoi??a I-2 ?aoeaioi??a a?noai?io /Iaeueieeiaa
?.TH.,Iiaeeiaa A.I., 1998; ?aoieeiaa I.A., N?a?iaaa ?.A.,1998; O?ea/eeia
A.A.. ? ni?aaao.,1998; Ua?aaeia I.E., O?e?i A.A., 1998; Mc Nulty C.A.M.,
Dent J.C., Wilkinson S.P., 1998/.

Canoinoaaiiy a eiiieaeni?e oa?ai?? aae?eiaaeoa??ico aioeaaeoa??aeueieo
i?aia?ao?a ?iaeoue aeooaeueiith i?iaeaio aea/aiiy a?ioeaiico oianoi?
eeoee. Inoaii?e iiaea aooe ii?ooaiei aei ii/aoeo aioeaaeoa??aeueii?
oa?ai??, ii?ooaiiy iiaeooue iineeeoeny a i?ioean? ?? i?iaaaeaiiy ?
caa?aaoeny i?ney cae?i/aiiy e?eoaaiiy /Neoieeiaa A.I., Eo?iiniaa I.A.,
Eaaaoiaa I.A., 1998; Ei?noinueeee A.A., Oaae?i A.?. ? ni?aaao.,
1998; Iaeeia A.E., 1998; Aiiaea?aiei A.I., Ai?a A.A., ? ni?aaao.,
1998; Eeeiaa A.A., Aiiaea?aiei A.I. ? ni?aaao., 1999/. Oea aecia/a?
iaiao?aei?noue aea/aiiy nenoaie a?ioeaiico oianoi? eeoee aei ii/aoeo
aioeaae?eiaaeoa?ii? oa?ai?? ? i?ney ?? i?iaaaeaiiy, aeey iaa?oiooaaiiy
iieaciee?a aei i?ecia/aiiy i?ia?ioee?a ? aeeoa?aioe?eiaaiiai c
a?aooaaiiyi nooiaiy ? oa?aeoa?o aeena?ioe/ieo ii?ooaiue oianoi? eeoee ?o
aeei?enoaiiy.

O iaae?ao?e/i?e i?aeoeoe? aeine?aeaeaiue, i?enay/aieo aea/aiith
i?e?ia?ioeaiico oianoi? eeoee i?e aae?eiaaeoa?-anioe?eiaai?e iaoieia?? a
ae?oae, iaaaaaoi, ? aiie iaiaeii??aei?. Aeai? i?i ii?ooaiiy i?e?iaiiai
iaecaaeo eeoa/ieea i?e aano?iaeoiaeaiaeuei?e iaoieia?? /Nieiaeiaiee
A.A., Neiii??ia I.A., 1997 ; Aaeaoiaa O.O., Aaoiaoiaa I.A., 1997 ;
Neiaiaeyi E.I., Aiy?/oe I.?., Eeeiithe N.?.,1998 ; Ii?iciaa I.A. ?
ni?aaao., 1998/ ia noi?iaiaeaeothoueny aeaieie i?i oa?aeoa? a?ioeaiico
oianoi? eeoee a caeaaeiino? a?ae iayaiino? aai a?aenooiino?
aae?eiaaeoa?ii? ?ioaeoe??. Iaaeinoaoiuei oaeiae aena?oeaia c?noaaeaiiy
nooiaith oyaeeino? aiaeineii?/ieo ci?i NIO ? AeIE ?c iayai?noth
aeena?ico oianoi? eeoee, ui iiaea aooe a?aei?aaiei ioieoii a?aaeaiiy
neeciai? iaieiiee i?aai?a aano?iaeoiaeaiaeueii? ciie ? ca?eueoeoe iayaio
iaoieia?th.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aea?aiee
iai?yiie aeine?aeaeaiue ca’ycaiee c iaoeiaith ae?yeuei?noth oa aoiaeeoue
aei oaiaoe/iiai ieaio eaoaae?e aeeoy/i? aano?iaioa?ieia?? Oa?e?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe, ye o?aaiaio IAe?: “?ic?iaea
iaoiae?a ae?aaiinoeee oa e?eoaaiiy o?ii?/ieo caoai?thaaiue o?aaii?
nenoaie o ae?oae.” (?a?no?aoe?eiee iiia? 0194V0035070)

Iaoa oa caaea/? aeine?aeaeaiiy. Iaoith ?iaioe aoei i?aeaeuaiiy
aoaeoeaiino? ?aaa?e?oaoe?? ae?oae c o?ii?/ieie
aae?eiaaeoa?-anioe?eiaaieie caoai?thaaiiyie i?aai?a
aano?iaeoiaeaiaeueii? ciie ia iniia? aea/aiiy iniaeeainoae a?ioeaiico
oianoi? eeoee ? aeeoa?aioe?eiaaii? ei?aeoe?? ii?ooaiue. A?aeiia?aeii aei
iinoaaeaii? iaoe aoee aecia/ai? ne?aeoth/? caaaeaiiy:

1. Aea/eoe iniaeeaino? aiaeineii?/ii? ea?oeie NIO oa AeIE o ae?oae,
?io?eiaaieo I?.

2. Aecia/eoe /anoioo ?io?eiaaiino? I? o ae?oae c
OAAeI.

3. Aecia/eoe iayai?noue aae?eiaaeoa?ii? ?ioaeoe?? oeyoii i?iaaaeaiiy
o?aaciiai oanoo, ?A, aaeoa??ieia?/iiai aeine?aeaeaiiy a?iioao?a neeciai?
iaieiiee aio?aeueiiai a?aeae?eo oeoiea.

4. Aea/eoe noai neeciai? iaieiiee oianoi? eeoee ca aeiiiiiaith
?aeoi?iiaiineii?/iiai ? ???aia?ao?/iiai aeine?aeaeaiue.

5. Ioe?ieoe noai a?ioeaiico oianoi? eeoee o ae?oae i?e o?ii?/ieo
caoai?thaaiiyo i?aai?a aano?iaeoiaeaiaeueii? ciie, anioe?eiaaieo ?
iaanioe?eiaaieo c I?.

6. C o?aooaaiiyi a?ioeaiico oianoi? eeoee iaa?oiooaaoe ? i?iaanoe
aeeoa?aioe?eiaaio oa?ai?th aae?eiaaeoa??ico.

7. Aea/eoe aieea aioeaaeoa??aeueii? oa?ai?? aae?eiaaeoa??ico ia noai
a?ioeaiico oianoi? eeoee ? c o?aooaaiiyi oeueiai ?ic?iaeoe
aeeoa?aioe?eiaai? ?aeiiaiaeaoe?? ii e?eoaaiith ii?aeiaiii? iaoieia??
(aae?eiaaeoa??ic ? aeenaaeoa??ic).

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a. I?iaaaeaii iaeii/ania
aeine?aeaeaiiy aaeoa??aeueii? oei?e aio?aeueiiai a?aeae?eo oeoiea ?
eeoeiai? i?e?ioei?e, ui aeicaieeei ?icoe?eoe oyaeaiiy i?i iaoiaaiaoe/i?
iaoai?cie ?io?eoaaiiy.

Aecia/aii /anoioo ?io?eiaaiino? I? i?e OAAeI o ae?oae ? iieacaiee ??
i?yiee ca’ycie ?c o?eaae?noth caoai?thaaiiy, a?eii aeeoeie ? nooiaiai
aiaeineii?/ieo ci?i NIO ? AeIE

Aecia/aii /anoioo aeyao o?ii?/iiai eie?oo i?e OAAeI, anioe?eiaaii? c
I?-?ioaeoe??th.

Aecia/aii /anoioo aeyao aeena?ioe/ieo ii?ooaiue oianoi? eeoee i?e
aano?iaeoiaeaiaeuei?e iaoieia?? o ae?oae.

Aeyaeai? a?aei?iiino? ae?aciino? aeena?ioe/ieo ii?ooaiue o caeaaeiino?
a?ae iayaiino? I? ? oa?aeoa?o aiaeineii?/ieo ci?i NIO ? AeIE.

Ia iniia? aeei?enoaiiy iieaciee?a a?ioeaiico oianoi? eeoee ?ic?iaeai?
e?eoa??? i?iaiicoaaiiy iiaeaeueoiai ?icaeoeo aae?eiaaeoa?-anioe?eiaaieo
caoai?thaaiue o ae?oae ? ?iaeea?aeoae?caoe?? e?eoaaeueii-i?io?eaeoe/ieo
caoiae?a.

Aea/aia aeeiai?ea noaio a?ioeaiico oianoi? eeoee o oai?eo i?ei?e/iei
aae?eiaaeoa??icii i?ae aieeaii o?eieaenii? oa?ai?? (aii?oeee?i
+iao?ii?aeacie +aea-iie).

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Iieacaii aeioe?euei?noue
aecia/aiiy nooiaiy eiioai?iaoe?? NIO ? AeIE aaeoa??yie ?iaeo
Helicobacter: aenieee nooi?iue ?io?eiaaiino? I? /ano?oa a?aei?/a?oueny
ia oii? aeano?oeoeaieo ci?i NIO, ei?aeth? c o?eaae?noth caoai?thaaiiy ?
iiaeiia a?aoiaoaaoeny i?e i?ecia/aii? ao?io?iiiiai e?eoaaiiy.

A?aecia/aii iecueeo ae?aaiinoe/io cia/ei?noue o?aaciiai oanoo aeey
ae?aaiinoeee I?-?ioaeoe??: o 31% oai?eo ?c iiceoeaiei o?aaciei oanoii
aaeoa??ieia?/ii aeae?eaiee ia I?, a noiooiy oei?a oeoiea: eeaan?aea,
a?eae ?iaeo eaiae?aea, eeoeiaa iaee/ea, cieioenoee noao?eieie,
aioa?iaaeoa???, i?ioae.

Aecia/aii ee?i?/ia cia/aiiy noaio a?ioeaiico oianoi? eeoee i?e OAAeI o
ae?oae: cia/i? aeena?ioe/i? ii?ooaiiy oianoi? eeoee (III nooi?iue
oyaeeino?) iaaaaeithaaee ia?aa?a iniiaiiai caoai?thaaiiy.

Aeyaeaia caeaaei?noue nooiaiy a?aaeaiiy neeciai? iaieiiee oianoi? eeoee
a?ae oeio aeena?ioe/ieo ii?ooaiue oianoi? eeoee , nooiaiy eiai
ae?aciino?.

Iieacaia aeioe?euei?noue aioeaaeoa??aeueii? oa?ai?? a eiiieaeniiio
e?eoaaii? i?ei?e/iiai aae?eiaaeoa??ico, yeee noi?iaiaeaeo?oueny
aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee: ao?io?iiia oa?ai?y ia o?eueee
i?ecaiaeeoue aei naiaoe?? I?, aea ? aeaaioai?ii aieeaa? ia oa?aeoa?
a?ioeaiico oianoi? eeoee.

Iieacaii, ui ?aoeeaeea I? noi?iaiaeaeo?oueny iia??oaiiyi iieaciee?a
a?ioeaiico oianoi? eeoee: oea aecia/a? iaiao?aei?noue iiaoi?ieo
aeine?aeaeaiue ? a?aaeeeaoe?eieo caoiae?a.

?acoeueoaoe aeine?aeaeaiiy c 1998 ?ieo ai?iaaaeaeaii a i?aeoe/io ?iaioo
aeeoy/eo ee?i?/ieo e?ea?aiue ?19, ?23 i. Oa?eiaa, aeeoy/i? iie?ee?i?ee
Eai?ia?aaenueeiai OII i. Ee?aa oa a iaa/aeueiee i?ioean i?e ?iaio? c
e?ea?yie-eo?naioaie ia eaoaae?? aeeoy/i? aano?iaioa?ieia?? Oa?e?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe.

Iniaenoee aianie caeiaoaa/a. Aaoi? i?aai?coaaa ee?i?ei-eaai?aoi?ia
ianoaaeaiiy 123 ae?oae ?c aano?iaeoiaeaiaeueiith iaoieia??th, i?e/iio
iniaenoi cae?enithaaa aiaeineii?/i? aeine?aeaeaiiy ? caa?? iaiao?aeiiai
iaoa??aeo aeey o?aaciiai, aaeoa??ieia?/iiai ? na?ieia?/iiai
aeine?aeaeaiue; cae?eniea aiae?c ? ocaaaeueiaiiy ?acoeueoao?a
aeine?aeaeaiiy; i?ia?a aeeoa?aioe?eia e?eoaaiiy iaoe??io?a; noi?ioethaaa
on? iieiaeaiiy, aeniiaee ? i?aeoe/i? ?aeiiaiaeaoe?? ?iaioe.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Ai?iaaoe?th ?iaioe i?iaaaeaii
ia i?aeeaoaae?aeuei?e eiioa?aioe?? eaoaae? aeeoy/i? aano?iaioa?ieia??,
iaae?ao???, oa?ai?? i?aee?oeiaiai a?eo, aeeoy/eo ?ioaeoe?eieo oai?ia,
iie?ee?i?/ii? iaae?ao???, ee?i?/ii? i?e?ia?ieia?? Oa?e?anueei? iaaee/ii?
aeaaeai?? i?neyaeeieiiii? ina?oe oa eaoaae?e oaeoeueoaonueei? iaae?ao???
c iaaee/iith aaiaoeeith Oa?e?anueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo.

Iaoa??aee aeena?oaoe?? aeeeaaeai? oa iaaiai?ai? ia tha?eaei?e
eiioa?aioe?? iieiaeeo a/aieo, i?enay/aii? 75-??//th canioaaiiy
Oa?e?anueeiai ?inoeoooo oaeineiiaeaiiy e?ea??a (Oa?e?a, 1998 ), ia
iaoeiai-i?aeoe/i?e eiioa?aioe?? «No/ani? iaoiaee ae?aaiinoeee oa
e?eoaaiiy — o i?aeoeeo ioi?iie caei?ia’y ae?oae» (Oa?e?a, 1999), ia III
iaoeiai-i?aeoe/i?e eiioa?aioe?? aeeoy/eo aano?iaioa?ieia?a Oe?a?ie
«Ae?aaiinoeea ? e?eoaaiiy oai?ia oeoieo oa aeaaiaaeoeyoeiaei? eeoee o
ae?oae» (Iaeana, 1999).

Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 12 ?ia?o, c yeeo 5 — o
oaoiaeo aeo?iaeao oa 7 — o oacao eiioa?aioe?e, c’?cae?a.

No?oeoo?a oa ianya aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 161
noi??ieao iaoeiiieno ? neeaaea?oueny ?c anooio, iaeyaeo e?oa?aoo?e,
iieno iaoiae?a aeine?aeaeaiiy, oanoe ?icae?e?a aeanieo niinoa?aaeaiue,
caeeth/ii? /anoeie, aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e. Nienie
aeei?enoaieo e?oa?aoo?ieo aeaea?ae iae?/o? 270 aeaea?ae
(172-a?o/eciyieo, 98-?iicaiieo, ui neeaaea? 27 noi??iie). ?iaioa
?ethno?iaaia 26 oaaeeoeyie (ui neeaaea? 12 noi??iie), 4 iaethieaie, 3
oioia?ao?yie (ui neeaaea? 3 noi??iee), 2 aeoyaaie c ?noi??? oai?iae.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy. Iniiao ?iaioe neeaaeathoue
?acoeueoaoe ee?i?ei-eaai?aoi?ii-?ino?oiaioaeueieo aeine?aeaeaiue 123
ae?oae o a?oe? a?ae 7 aei 15 ?ie?a. Na?aae ieo AOO ae?aaiinoiaaii o
aeaio ae?oae, AOAeIE — o 5 ae?oae, 116 – OAAe, i?e/iio o 20 c ieo
a?aei?/aee a?iceai? a?aaeaiiy NIO ? AeIE. Ia?aaaaeaee ae?oe noa?oiai
a?eo, ca noaooth — ae?a/aoa.

Ii?yae c caaaeueiiee?i?/ieie, ianoaaeoaaiei ae?oyi i?iaiaeeeeny
aaeoa??ieia?/i? oa ?ino?oiaioaeuei? iaoiaee aeine?aeaeaiiy.

An?i ae?oyi i?iaaaeaii OAAAeN aa?oi?o a?aeae?e?a o?aaiiai o?aeoo aeey
ioe?iee noaio neeciai? iaieiiee oa aa??o?eaoe?? iniiaiiai ae?aaiico ca
aeiiiiiaith aeei?enoaiiy aio/eiai aiaeineiio yiiinueei? o??ie “OLIMPUS”.
Aeey ioe?iee nooiaiy ci?i NIO oa AeIE aeei?enoiaoaaee aeai? I.A.
Iaco??ia, I.I. Cai?oaeiiai (1984). Aiaeineii?/ia aeine?aeaeaiiy a
aeeiai?oe? aeeiioaaee c i?eoe?eueiith a?iin??th neeciai? iaieiiee
aio?aeueiiai a?aeae?eo oeoiea c ianooiiith ae?aaiinoeeith
aae?eiaaeoa?ii? ?ioaeoe??

Aeey ae?aaiinoeee I? aeei?enoiaoaaee o?aaciee oano, aaeoa??ieia?/iee
iaoiae aeine?aeaeaiiy ? ?A, ye? i?iaiaeeee a eaai?aoi??? ee?i?/ii?
i?e?ia?ieia??

(caa. — eaiae. iaae. iaoe A.O.Aey/aiei) Oa?e?anueeiai IAe? i?e?ia?ieia??
? ?ioiieia?? ?i. ?.?. Ia/ieeiaa.

Nae?aoi?io ooieoe?th oeoieo aecia/aee o 76 ae?oae ca aeiiiiiaith
?io?aaano?aeueii? ?I-iao??? aeaiieeaiei ciiaeii (TH.ss. Eae, 1987).

Aeni?an-ae?aaiinoeeo, a oaeiae c’ynoaaiiy noiooiuei? iaoieia??
aeeiioaaee ca aeiiiiiaith OCAe i?aai?a /a?aaii? ii?iaeieie (?.A.
Aeai?yeianueeee ? ni?aaao., 1987).

Aeey ioe?iee noaio neeciai? iaieiiee oianoi? eeoee 55 ae?oyi c
ee?i?/ieie i?iyaaie eie?oo i?iaiaeeeiny ?aeoi?iiaiineii?/ia oa
???aia?ao?/ia aeine?aeaeaiiy. Aiaeineii?/i? ci?ie neeciai? iaieiiee
oianoi? eeoee ioe?ithaaee ca eeaneo?eaoe??th TH.A. A?eioniaa, A.I.
Aeai?eiaa (1994).

Aeine?aeaeaiiy a?ioeaiico oianoi? eeoee i?iaiaeeee 123 ae?oyi ia
eaoaae?? ee?i?/ii? i?e?ia?ieia?? (caa. eao. — i?io. TH.E. Aieyinueeee)
OIAII. Aeey ioe?iee noaio a?ioeaiico oianoi? eeoee aeei?enoiaoaaee
ee?i?/io, iaie iiaeeo?eiaaio eeaneo?eaoe?th A.O. A?e?a?ia (1970).
Aeine?aeaeaiiy i?iaiaeeee a aeeiai?oe?: ia ii/aoeo aioeaae?eiaaeoa?ii?
oa?ai??, /a?ac i?nyoeue i?ney ?? cae?i/aiiy oa o eaoaiiac? /a?ac 6-12
i?nyoe?a

?acoeueoaoe aeine?aeaeaiiy. A caeaaeiino? a?ae ?io?eiaaiino? I? oai??
aoee ?iciiae?eai? ia 2 a?oie. Iniiaio a?oio neeaaeaea 101 aeeoeia c
OAAeI, o yeeo aoa ?aeaioeo?eiaaiee I?, eiio?ieueio a?oio — 22 aeeoeie, o
yeeo I? aeae?eaiee ia aoa.

Caaaeueia ?io?eiaai?noue I? neeaaeaea 82,1% (101 aeeoeia). I?e
aeano?oeoeaieo ci?iao NIO ? AeIE I? aeyaeaii o 26 (96,3%) ae?oae, i?e
iiaa?oiaaeo — o 75 (78,1%) ae?oae. ?io?eiaaiiino? I? /ano?oa
i?aeaeaaaeeny ae?a/aoa – 53,6% ae?oae. ?io?eiaaii?noue I?
i?aeaeuoaaeanue i?iii?oe?eii a?eo oa o?eaaeino? aano?iaioa?ieia?/iiai
aiaiiaco: na?aae ae?oae 7-9 ?ie?a – anueiai 9,9 % I? (+) oi?i
caoai?thaaiue i?ioe 61,4% a a?oi? oai?eo a?eii 12-15 ?ie?a (? < 0,001); i?e o?eaaeino? caoai?thaaiiy aei ?ieo I? aoa aeae?eaiee o 17,8% ae?oae, o 46,5% ae?oae - i?e o?eaaeino? caoai?thaaiiy a?eueo o?ueio ?ie?a (? < 0,001). Iaoyaeaio niaaeeia?noue c aea/a?ii? iaoieia?? aeyaeaii i?eaeecii o an?o a?oi oai?eo, i?ioa aiia ia aieeaaea ia i?enooi?noue I?. Na?aae noiooiuei? iaoieia??, iacaeaaeii a?ae ian?iai?iiy I?, o oai?eo an?o a?oi /ano?oa ca ?io? cono??/aeenue i?aai?/i? a?aaeaiiy a?e?a?ii? nenoaie - o?ii?/iee oieaoeenoioieaia?o o 55,4% ae?oae iniiaii? a?oie ? o 72,7% ae?oae - eiio?ieueii?. I?eaeecii c iaeiaeiaith /anoioith (55% - 40%) o oai?eo iaio a?oi cono??/aeanue o?ii?/ia iaoieia?y oianoi? eeoee. O 88,9% ae?oae c OAAeI, anioe?eiaaii? c I?, a?aei?/ai? oiiia? caoai?thaaiiy, ye? ni?eyee ?icaeoeo oa o?ii?caoe?? aano?iaeoiaeaiaeueii? iaoieia??. Iaea?eueo cia/iei a i?ioeaioiiio a?aeiioaii? aoa aenieee ?ioaeoe?eiee ?iaeaen – o 44,6% ae?oae, o 30,4% ae?oae – ANAe, ??aeoa cono??/aeeny aea?a?/iee aea?iaoeo, o?ii?/iee oiicee?o. Aiae?c ee?i?/ieo i?iya?a o?ii?/ieo aae?eiaaeoa?-anioe?eiaaieo caoai?thaaiue i?aai?a aano?iaeoiaeaiaeueii? ciie o ae?oae iieacaa, ui iaoiaiiiii?/i? ee?i?/i? iciaee, aeanoea? o?eueee I? - ?ioaeoe??, aeyaeoe ia aaeaeinue, i?ioa anoaiiaeai? aeanoea? i?ei?e/iiio aae?eiaaeoa??ico a?aei?iiino? ii ye?niiio oa?aeoa?o aieueiaiai neiae?iio: aaeeea ae?aci?noue ? o?eaae?noue aieueiaiai neiae?iio. I?e iayaiino? ?io?eiaaiiino? I? ia?aaaaeaa a?ia?aoeeaeiee noai oeoieiai? nae?aoe?? o 66 (86,8%) ae?oae, ??aeoa ae?aaiinoiaaiee ii?iiaoeeaeiee noai – o 9 (11,8%) ae?oae (? < 0,001). A ?acoeueoao? aiaeineii?/iiai aeine?aeaeaiiy aa?oi?o a?aeae?e?a o?aaiiai o?aeoo anoaiiaeaii, ui i?e I?–anioe?eiaaieo aa??aioao aano?iaeoiaeaiaeueii? iaoieia?? niinoa??aathoueny a?eueo cia/i? oa aeeaie? ci?ie c aeano?oeoe??th neeciai? iaieiiee. Iaea?eueo ?iciianthaeaeaiei aa??aioii a?aaeaiiy NIO ? AeIE o 52% ae?oae aeyaeany iiaa?oiaaee aano?eo, o 61% ae?oae - iiaa?oiaaee aeoiaeai?o. Aeano?oeoeai? ci?ie NIO ? AeIE ae?aaiinoiaaii o 19 (18,8%) ae?oae o aeaeyae? a?iceaieo ci?i ? a 7 (6,9%) ae?oae – AO. A?ic?? aaea?/? /ano?oa cono??/aeeny a AeIE (ia?aaaaeii a oeeaoeei?), i?ae o oeoieo (4,9% oa 1,9%). Iaeeie/i? ae?acee, ia?aaaaeii 1 oa 2 noaae??, aeyaeai? eeoa a AeIE. Ia i?aenoaa? ?acoeueoao?a OAAAeN aoee anoaiiaeai? aiaeineii?/i? iniaeeaino?, aeanoea? i?ei?e/iiio aae?eiaaeoa??ico - iiaa?oiaa? ci?ie NIO ? AeIE, ye? i?iyaeyeeny a?eueo ae?aaeaiith caiaeueiith ? noaeeiiith ?aaeoe??th o aeaeyae? yne?aai?, aeeoocii? a?ia?ai??, iaa?yeo neeciai? iaieiiee ia?aaaaeii aio?aeueiiai a?aeae?eo oeoiea ? AeIE, a?ia?nae?aoe??th, iayai?noth a oeoieo iooii? ??aeeie c aeii?oeaie neeco. I?ae /an aiaeineii?/iiai aeine?aeaeaiiy o 52 (42,3%) ae?oae ?a?no?oaaee noiooi? a?aaeaiiy no?aaioiaeo ? ii?ooaiiy iioi?ii? ooieoe?? oeoiea oa AeIE. I? ?ioaeoe?y /ano?oa noi?iaiaeaeoaaea AeA?, yeee aoei aeyaeaii o 39 (76,5%) ae?oae (? < 0,001). Ia ia?oiio aoai? ae?aaiinoeee I? 123 ae?oyi i?iaiaeeany o?aaciee oano, yeee aeyaeany iiceoeaiei o 101 aeeoeie. An?i oai?ei c iiceoeaiei o?aaciei oanoii iaeii/anii i?iaiaeeeiny aaeoa??ieia?/ia aeine?aeaeaiiy oa ?A. Aiae?c io?eiaieo ?acoeueoao?a iieacaa, ui o 31 % ae?oae c iiceoeaiei o?aaciei oanoii, aaeoa??ieia?/ii aoa aeae?eaiee ia I?, a noiooiy oei?a oeoieo: eeaan?aea, a?eae ?iaeo eaiae?aea, eeoeiaa iaee/ea, aioa?iaaeoa???, noao?eieie, no?aioieie, ui na?ae/eoue i?i iecueeo ae?aaiinoe/io cia/ou?noue o?aaciiai oanoo. O?aaciee oano iiaeia ?icaeyaeaoe eeoa a yeino? i???ioiaiiai. Aaeoa??ieia?/ia aeine?aeaeaiiy aeyaeeiny iiceoeaiei o 57% ae?oae, ?A -o 49% ae?oae, ui na?ae/eoue i?i ii??aiyii?noue ?acoeueoao?a ?A oa aaeoa??ieia?/iiai aeine?aeaeaiiy, aea ia?aaaao iio??aii a?aeaeaaaoe inoaiiueiio iaoiaeo aeine?aeaeaiiy. I?e iaeii/aniiio aeei?enoaii? o?aaciiai oanoo ? aaeoa??ieia?/iiai aeine?aeaeaiiy /anoioa iiceoeaieo ?acoeueoao?a c?inea aei 59 %; i?e iaeii/aniiio i?iaaaeaii? o?aaciiai oanoo, aaeoa??ieia?/iiai aeine?aeaeaiiy ? ?A - aei 61 % . Io?eiai? ?acoeueoaoe na?ae/eee i?i oa, ui ?ioi?iaoeai?noue ae?aaiinoeee I? c?inoa? i?e iaeii/aniiio i?iaaaeaii? o?ueio ao?ieia?/ieo iaoiae?a aeine?aeaeaiiy, aea o iaae?ao?e/i?e i?aeoeoe? oe?eeii aeinoaoiuei aeei?enoaiiy iaeiiai iaoiaea, aea?? yeiai caeaaeeoue a?ae nooiaiy ?iaaceaiino? ? ni?iiiaeiino? e?eoaaeueiiai caeeaaeo. Aeey aeeiiaiiy iniiaieo caaea/ aeine?aeaeaiiy 55 ae?oyi c ee?i?/ieie i?eciaeaie eie?oa i?iaiaeeee ?aeoi?iiaiineii?/ia e ???aia?ao?/ia aeine?aeaeaiiy neeciai? iaieiiee oianoiai eeoa/ieeo. Aiaeineii?/i? aeine?aeaeaiiy oianoi? eeoee na?ae/eee i?i oa, ui i?e OAAeI, anioe?eiaai?e c I?, o 37 (80,4%) ae?oae ae?aaiinooaaee caiaeuei? ci?ie neeciai? iaieiiee oianoi? eeoee. Aiae?coth/e iaoiaaiaoe/i? oaeoi?e ?icaeoeo caiaeueieo ci?i neeciai? iaieiiee oianoiai eeoa/ieeo o ae?oae c OAAeI, anioe?eiaaii? c I?, caa?oaee oaaao ia ??cio nooi?iue ii?ooaiue a?ioeaiico oianoi? eeoee. O 10 (27%) ae?oae ?a?no?oaaee I nooi?iue aeena?ioe/ieo ii?ooaiue oianoi? eeoee, o 12 (32,5%) aeaoae – II nooi?iue oa III nooi?iue - o 15 (40,5%) ae?oae. Io?eiai? ?acoeueoaoe na?ae/eee i?i oa, ui caiaeuei? ci?ie neeciai? iaieiiee oianoi? eeoee o 40% ae?oae aoee iaoiiaeai? cia/ieie aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee (III nooi?iue oyaeeino?). Oea noaei i?eaiaeii aeeth/aiiy i?ia?ioee?a o eiiieaenio oa?ai?th OAAeI o ae?oae. Aeine?aeaeaiiy a?ioeaiico oianoi? eeoee i?iaaaeai? 123 oai?ei a aeeiai?oe?. A ia??iae caaino?aiiy OAAeI o ae?oae an?o a?oi o 100% aeiaaee?a ?a?no?oaaee aeena?ioe/i? ii?ooaiiy oianoi? eeoee, ui oa?aeoa?ecoaaeeny e?euee?nieie ci?iaie aiaa?iaiiai eiiiiiaioo ? ye?nieie ci?iaie aa?iaiiai. Oe? iieacieee ciaoiaeeeeny a i?yi?e caeaaeiino? a?ae i?enooiino? aae?eiaaeoa?ii? ?ioaeoe??. I?e OAAeI, anioe?eiaai?e c I?, ua aei ii/aoeo aioeaae?eiaaeoa?ii? oa?ai??, aoee ae?aaeai? aeena?ioe/i? ii?ooaiiy oianoi? eeoee: ia oii? aeao?oeeoo iae?aaoii? i?e?ioei?e (a?o?aeiaaeoa??e – o 82 % ae?oae, eaeoiaaoeee - o 66% ae?oae, eeoeiai? iaee/ee - o 20% ae?oae) a?aecia/aeiny c?inoaiiy oiiaii-iaoiaaiieo i?e?ii?aai?ci?a (eeaan?aea, oeeo?iaaeoa?, cieioenoee noao?eieie, a?eae ?iaeo eaiae?aea, i?ioae). A eiio?ieuei?e a?oi? ae?oae aeao?oeeo a?o?aeiaaeoa??e - o 86% oai?eo, eaeoiaaoeee - o 68% oai?eo noi?iaiaeaeoaaany ye?nieie ci?iaie eeoeiai? iaee/ee. O 36% ae?oae a?aeaoaaeany cai?ia oeiiai? eeoeiai? iaee/ee ia aoei?/io - eaeoiciiaaaoeaio ? o 9% ae?oae - aaiie?coth/o. (oaae.1). Oaaeeoey 1 Noai i?e?ioei?e eeoa/ieea i?e OAAeI a ae?oae c a?aooaaiiyi aae?eiaaeoa?ii? ?ioaeoe?? Iaeiaioaaiiy i?e?ii?aai?ci?aE?euee?noue i?e?iaieo o?e o 1 a oaeae?e o ii?i?E?euee?noue i?e?iaieo o?e o 1 a oaeae?e o oai?iaiIniiaia a?oiaEiio?ieueia a?oiaa?o?aeiaaeoa???107-108aei 10783 (82%)19 (86,3%)eaeoiaaoeeee106-107aei 10667 (66%)15 (68,1%)aaeoa?i?aee107-1010aei 1073 (2%)-eeino?eae??aei 104aeua 1046 (5%)-eeoeiaa iaee/ea c ii?iaeueiith oa?iaioaoeaiith aeoeai?noth 107-108 aei 107 21(20%) 8 (36,3%)eeoeiaa iaee/ea ?c cieaeaiith oa?iaioaoeaiith aeoeai?noth 106-107 aeua 107 12 (11%) 2(9%)eeoeiaa iaee/ea a?aenooiyii?ia 1010011 (10%)4 (18,1%)aioa?ieiee105-106 aei 105 aeua 1053 (2%) 4 (3%)3 (13,6%) 2 (9%)eaeoiciiaaaoeaia eeoeiaa iaee/ea 0 104-107 1 (0,9%) 2 (9%)aaiie?coth/a eeoeiaa iaee/ea 0 104-107 8 (7%) 2 (9%)aaiie?coth/ee noao?eieie0104-1063 (2%)1 (4,5%)cieioenoee noao?eieie0104-10716 (15%)1 (4,5%)a?eae ?iaeo eaiae?aeaaei 104105-10716 (15%)-i?ioaeaei 104105-1066 (5%)-oiiaii-iaoiaaii? aioa?iaaeoa??? aei103 aeua 103 28 (27%) 5 (22,7%) Aiae?c i?iaaaeaieo ?acoeueoao?a aeine?aeaeaiue na?ae/ea i?i oa, ui i?e OAAeI, anioe?eiaai?e c I?, nooi?iue oyaeeino? aeena?ioe/ieo ii?ooaiue oianoi? eeoee iaoiiaeaia oioaeueiei cieaeaiiyi iniiaieo iieaciee?a iae?aaoii? i?e?ioei?e (a?o?aeiaaeoa???, eaeoiaaoeeee, eeoeiaa iaee/ea), ui ni?eyei eieii?caoe?? neeciai? iaieiiee eeoa/ieea a 27,7% oai?eo ie?aiei (?cieueiaaiei) aeaeii oiiaii -iaoiaaiii? i?e?ioei?e. Nooi?iue oyaeeino? aeena?ioe/ieo ii?ooaiue oianoi? eeoee i?e aae?eiaaeoa?-anioe?eiaai?e aano?iaeoiaeaiaeuei?e iaoieia?? ciaoiaeeeany a i?yi?e caeaaeiino? a?ae oa?aeoa?o aiaeineii?/ieo ci?i NIO oa AeIE (oaae.2). Oaaeeoey 2 Nooi?iue oyaeeino? aeena?ioe/ieo ii?ooaiue oianoi? eeoee i?e OAAeI o ae?oae a caeaaeiino? a?ae oi?i a?aaeaiiy NIO oa AeIE Nooi?iue oyaeeino? aeena?ioe/ieo ii?ooaiueOi?ia a?aaeaiiy NIO oa AeIEaeano?oeoeaiacaiaeueia I6 (23,1%)40 (53,4%)II8 (30,8%)25 (33,3%)III12 (46,1%)10 (13,3%)Anaai26 (100%)75 (100%) I?e a?iceaii–ae?aceiaeo i?ioeanao NIO ? AeIE o 46,1% ae?oae (?<0,05) niinoa??aaee a?eueo aeeaie? aeena?ioe/i? ii?ooaiiy oianoi? eeoee (III nooi?iue). Cia/i? aeena?ioe/i? ii?ooaiiy oianoi? eeoee i?e OAAeI, anioe?eiaaii? c I?, noaee iai?yiei i?aeoaa?aeaeaiiyi o?eaaei? eiioai?iaoe??? I?, aecia/aee aino?ioo i?ioeano, a oaeiae aeeaeio a?aaeaiiy NIO ? AeIE. Io?eiai? aeai? a eiiieaen? c ae?oaeie ae?aaiinoe/ieie e?eoa??yie aeicaieeee i?iaiicoaaoe iani?eyoeeaee ia?aa?a OAAeI (ca?eueoaiiy e?eueeino? e?aeei-aei?a, o?eaaeino? aieueiaiai ? aeeniaioe/iiai neiae?ii?a, iiaeiaaeaiiy ?aia?aoe?? a?iceaii-ae?aceiaeo i?ioean?a NIO ? AeIE). I?e OAAeI, anioe?eiaaii? c I?, o 63 (62,3%) ae?oae ae?aaiinoiaaii aeenaaeoa??ic oianoi? eeoee, yeee i?io?eaa a noaeiiiainiaai?e oi?i? ? noi?iaiaeaeoaaany ae?aaeaieie ee?i?/ieie i?iyaaie: 28 (44,4%) ae?oae nea?aeeeenue ia iaoai?eci, 39 (61%) ae?oae - ia a?eue o e?aiio aioe?, a 24 (38%) aeeoeie – a i?eioieia?e iaeano?; o 51 (80%) oai?iai ?a?no?oaaee ii?ooaiiy aeii?iaeiaiiy o aeaeyae? caii?o aai o 5 (7,9%) ae?oae – iano?eeiai aeii?iaeiaiiy. I?e iaeueiaoe?? aeeaioa o 32 (50%) ae?oae a?aei?/aee aie?ni?noue ii oiaeo oianoiai eeoa/ieeo, o 16 (25%) ae?oae – a e?a?e eeoaia?e ae?eyioe?. Oei a?eueo, ui o oeeo ae?oae c aeenaaeoa??icii oianoi? eeoee, ca?aeii aeaieo ?aeoi?iiaiineii?? ? ???aia?ao??, aoee aeyaeai? caiaeuei? i?ioeane neeciai? iaieiiee oianoiai eeoa/ieeo. Aeenaaeoa??ic oianoi? eeoee oneeaaeithaaa ia?aa?a OAAeI, ui aeiaaaei ei?aeoe?? aeyaeaieo ii?ooaiue. Aeyaeai? ci?ie noaio i?e?ioei?e oeoieo, oianoi? eeoee, a?iceaii-ae?aceia? i?ioeane NIO oa AeIE o ae?oae yaeeenue iieacaiiyi aei i?ecia/aiiy ii?aeiaii? aioeaaeoa??aeueii? oa i?ia?ioe/ii? oa?ai?? aae?eiaaeoa?–anioe?eiaaieo caoai?thaaiue. Canoinoaaiiy a eiiieaeni?e oa?ai?? aae?eiaaeoa??ico aioeaaeoa??aeueieo i?aia?ao?a yaeeinue aacoiiaiei iieacaiiyi aei ?aiiueiai i?ecia/aiiy i?ia?ioee?a. Eiiieaenia oa?ai?y ae?oae ?c OAAeI, anioe?eiaaii? c I?, aoea ni?yiiaaia ia naiaoe?th NIO a?ae aae?eiaaeoa?ii? ?ioaeoe??, ei?aeoe?th aeyaeaieo aeena?ioe/ieo ii?ooaiue oianoi? eeoee, i?aeaeuaiiy eieii?caoe?eii? ?acenoaioiino? neeciai? iaieiiee oianoiai eeoa/ieea. Aei neeaaeo eiiieaenii? oa?ai?? i?ei?e/iiai aae?eiaaeoa??ico ia oii? ae??oe/iiai ?aaeeio aoiaeeee aioeaae?eiaaeoa?i? i?aia?aoe, aeieaoi?e I-2 ?aoeaioi??a a?noai?io, aioaoeeaei? ? i?ioecaiaeuei? i?aia?aoe, ?aia?aioe, naaeaoeaia oa?ai?y, i?ia?ioeee. Iniiao aioeaae?eiaaeoa?ii? oa?ai?? neeaee aioeaaeoa??aeuei? i?aia?aoe: aii?oeee?i, aiien?oeee?i, oeaiienei, a?eo?ii?oeei, ye? i?ecia/aeeny a eiia?iaoe?? c iao?ii?aeacieii aai oo?acie?aeiiii, eiia?iiaaiee aioeaaeoa??aeueiee aano??enueeee i?aia?ao “Oae?eioeei”. Eo?n a?aaeeeaoe?eii? oa?ai?? neeaaeaa 7 aei?a. Ia 3-5 aeaiue aioeaae?eiaaeoa?ii? oa?ai?? i?iaiaeeee ei?aeoe?th aeena?ioe/ieo ii?ooaiue oianoi? eeoee ca aeiiiiiaith eeane/ieo aoa?ioee?a (eie? -, a?o?aeoi-, eaeoiaaeoa?ei) ? naiiye?i?ioth/eo aioaaii?no?a (aaeoenoaoee). Eo?n i?ia?ioee?a neeaaeaa 150 aeic eiaeiiai i?aia?aoo. O 46 ae?oae /a?ac i?nyoeue i?ney cae?i/aiiy eo?no aioeaae?eiaaeoa?ii? oa?ai??, aea/aee aeeiai?eo ee?i?/ieo i?iya oa ia?aee?i?/ieo iieaciee?a. Aiane?aeie i?iaaaeaiiai e?eoaaiiy niinoa??aaee iiceoeaio ee?i?/io aeeiai?eo: a?aenooi?noue o 27 (58,6%) ae?oae aieueiaiai (?<0,001) oa o 35 (76%) ae?oae - aeeniaioe/iiai neiae?ii?a (?<0,001). I?e iaeueiaoe?? aeeaioa o 11 (23%) ae?oae caa??aaeanue eieaeueia aie?ni?noue a ai?aano?aeuei?e ae?eyioe?, o 6 (13%) ae?oae – ii oiaeo eeoa/ieeo. Ia oii? e?ea?aeaoe?? aai cia/iiai ciaioaiiy iniiaieo ee?i?/ieo neiioii?a caoai?thaaiiy ?a?no?oaaee iiceoeaio aiaeineii?/io aeeiai?eo - ciaioeany iaa?ye ? a?ia?ai?y NIO ? AeIE, caai?iiy a?iceaieo ? ae?aceiaeo aeano?oeoe?e. I?e i?iaaaeai? eiio?ieueii? OAAAeN an?i 46 oai?ei i?iaiaeeee i?eoe?eueio a?iin?th aio?aeueiiai a?aeae?eo oeoieo c ianooiiith iinoaiiaeith o?aaciiai oanoo, aaeoa??ieia?/iiai aeine?aeaeaiiy. O 12 (26%) ae?oae o?aaciee oano aoa iaaaoeaiei, o 34 (74%) ae?oae – iiceoeaiei. An?i ae?oyi c iiceoeaiei o?aaciei oanoii i?iaiaeeee aaeoa??ieia?/ia aeine?aeaeaiiy i?e?ioei?e oeoieo, yea iieacaei o 96% aeiaaee?a a?aaeeeaoe?th I? ? cia/ia ciaioaiiy e?eueeino? noiooiuei? i?e?ioei?e (?<0,05). Ia?aeaeueia aeine?aeaeaiiy a?ioeaiico oianoi? eeoee na?ae/eei i?i ii?iae?caoe?th o 13 (28,3%) ae?oae iieaciee?a a?ioeaiico oianoi? eeoee. O 33 (71,7%) ae?oae (?<0,001) a?aei?/aii iie?ioaiiy e?euee?nieo ? ye?nieo iieaciee?a i?e?ioei?e oianoiai eeoa/ieea: ??no iae?aaoii? i?e?ioei?e ? ciaioaiiy oiiaii- iaoiaaiii? (?en.1). * - ? < 0,001 ?enoiie 1. I?e?ioei?a oianoi? eeoee aei ? i?ney e?eoaaiiy Ii in? aanoeen – iaeiaioaaiiy aaeoa??e, ii in? i?aeeiao – e?euee?noue i?e?iaieo ee?oei a 1 a oaeae?e. Aiae?c io?eiaieo ?acoeueoao?a e?eoaaiiy na?ae/ea, ui ao?io?iiia oa?ai?y aae?eiaaeoa??ico c aeei?enoaiiyi aioeaaeoa??aeueieo i?aia?ao?a ia o?eueee i?ecaiaeeea aei naiaoe?? NIO a?ae I?, aea e aeaaioai?ii aieeaaea ia oa?aeoa? a?ioeaiico oianoi? eeoee. Iiaeaeueoa iayai?noue aeena?ioe/ieo ii?ooaiue oianoi? eeoee (o 71,7% ae?oae) ia oii? ee?i?ei-aiaeineii?/ii? ?ai?n?? oa aoaeoeaii? a?aaeeeaoe?? I? aeicaieeee c?iaeoe aeniiaie eeoa i?i aeaeeia caoooaiiy aino?ioe i?ioeano caoai?thaaiiy. A?aenooi?noue ?aeiiaiaeiaaieo ?iaeea?aeoaeueieo e?eoaaeueieo caoiae?a, iai?aaeaieo ia ii?iae?caoe?th noaio a?ioeaiico oianoi? eeoee i?eaiaeeee aei ?aiiueiai ?aoeeaeeao caoai?thaaiiy. Oe? aeai? i?aeoaa?aeeee iao i?iaiic i?i iani?eyoeeaee ia?aa?a OAAeI, anioe?eiaaii? c I?, yea noi?iaiaeaeo?oueny aeenaaeoa??icii oianoi? eeoee. I?i oea na?ae/eee iao? niinoa?aaeaiiy ca ae?oueie /a?ac 6-12 i?nyoe?a i?ney aeienee ?c noaoe?iia?o. Eaoaiianoe/i? aeine?aeaeaiiy, i?iaaaeai? /a?ac 6-12 i?nyoe?a o 25 ae?oae c aoaeoeaiith a?aaeeeaoe??th ai?iaeiaae i?nyoey i?ney cae?i/aiiy aioeaaeoa??aeueii? oa?ai??, aeyaeee o 7 ae?oae ee?i?ei - aiaeineii?/ia caaino?aiiy caoai?thaaiiy: o 1 aeeoeie ca?a?no?iaaii ?aoeeaeea AOAeIE, o 1 aeeoeie – ae?aaiinoiaaii ae?aceo oeeaoeeie AeIE ? o 4 ae?oae - caaino?aiiy aano?iaeoiaeai?oo o aeaeyae? caiaeueiiai i?ioeano oeoieo ? AeIE. I?e aaeoa??ieia?/iiio aeine?aeaeaii? a?iioaoa neeciai? iaieiiee aio?aeueiiai a?aeae?eo oeoieo o 3 ae?oae ia oii? ee?i?ei-aiaeineii?/iiai caaino?aiiy aeyaeee iayai?noue I?. Aoaeoeai?noue ii?aeiaii? aioeaaeoa??aeueii? ? i?ia?ioe/ii? oa?ai?? neeaea 88%. ?aoeeaeea aae?eiaaeoa?ii? ?ioaeoe?? noi?iaiaeaeoaaany iia??oaiiyi iieaciee?a a?ioeaiico oianoi? eeoee: iiaeaeueoa cieaeaiiy iae?aaoii? i?e?ioei?e ? c?inoaiiy oiiaii-iaoiaaiieo i?e?ii?aai?ci?a o i?e?iaieo anioe?aoe?yo, ui iaiao?aeii a?aoiaoaaoe i?e iiaoi?ieo eo?nao a?aaeeeaoe?eii? oa?ai??, aeeth/ath/e a eiiieaenia e?eoaaiiy i?ia?ioeee. Oaeei /eiii, o?ii?/i? aae?eiaaeoa?-anioe?eiaai? caoai?thaaiiy i?aai?a aano?iaeoiaeaiaeueii? ciie, ua aei ii/aoeo aioeaae?eiaaeoa?ii? oa?ai?? noi?iaiaeaeoaaeeny aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee. I?e o?eaae?e eiioai?iaoe?? I? a?aeaoaathoueny cia/i? ii?ooaiiy a?ioeaiico oianoi? eeoee (aeenaaeoa??ic oianoi? eeoee), ye? oneeaaeiththoue ia?aa?a OAAeI ? cieaeothoue aoaeoeai?noue e?eoaaiiy. O eiiieaeniiio e?eoaaii? i?ei?e/iiai aae?eiaaeoa??ico, yeee noi?iaiaeaeo?oueny aeenaaeoa??icii oianoi? eeoee, aeioe?eueii canoinoaaiiy ii?aeiaii? aioeaaeoa??aeueii? ? i?ia?ioe/ii? oa?ai??, ui ia o?eueee i?ecaiaeeoue aei naiaoe?? NIO a?ae I?, aea ? aeaaioai?ii aieeaa? ia oa?aeoa? a?ioeaiico oianoi? eeoee. AENIIAEE 1. O no?oeoo?? o?ii?/ieo caiaethaaeueieo ? aeano?oeoeaieo caoai?thaaiue i?aai?a aano?iaeoiaeaiaeueii? ciie a ae?oae aae?eiaaeoa?-anioe?eiaai? oi?ie neeaaeathoue 82,1%. ?io?eiaai?noue I? /ano?oa aeyaey?oueny ia oii? aeano?oeoeaieo ci?i NIO ? AeIE, ia?inoa? i?iii?oe?eii o?eaaeino? aano?iaioa?ieia?/iiai aiaiiaco, a?eo aeeoeie. 2. I?e aeyaeai? I?-?ioaeoe?? ?ioi?iaoeai?noue aaeoa??ieia?/iiai aeine?aeaeaiiy neeaaea? 57%, ?A –49%. O?aaciee oano iiaeia ?icaeyaeaoe eeoa ye i???ioiaiee (iiia?aaei?e). 3. O?ii?/ia aano?iaeoiaeaiaeueia iaoieia?y a ae?oae o 100% aeiaaee?a noi?iaiaeaeo?oueny aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee. I?e OAAeI, anioe?eiaaii? c I?, o 62,3% ae?oae ae?aaiinoiaaii aeenaaeoa??ic oianoi? eeoee, yeee i?io?ea? a noaeiiiainiaai?e oi?i? ? oa?aeoa?eco?oueny ae?aaeaieie ee?i?/ieie i?iyaaie. 4. Nooi?iue oyaeeino? aeenaaeoa??ico oianoi? eeoee caeaaeeoue a?ae iayaiino? aae?eiaaeoa?ii? ?ioaeoe?? ? oa?aeoa?o aiaeineii?/ieo ci?i neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie. 5. OAAeI, anioe?eiaaia c I?, o 80,4% ae?oae noi?iaiaeaeo?oueny caiaeaiiyi neeciai? iaieiiee oianoi? eeoee, yea o 40 % ae?oae iaoiiaeaia cia/ieie (III nooi?iue oyaeeino?) aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee. 6. *anoioa ? ae?aaeai?noue aeenaaeoa??ico oianoi? eeoee i?e o?ii?/ieo I? - anioe?eiaaieo caoai?thaaiiyo aano?iaeoiaeaiaeueii? ciie o ae?oae aecia/a? iaiao?aei?noue iaaeeeaiaioicii? ei?aeoe?? ci?i c aeei?enoaiiyi i?ia?ioee?a ia oii? aioeaae?eiaaeoa?ii? oa?ai?? oa i?ioecaiaeueieo cania?a. 7. Ao?io?iiia oa?ai?y aae?eiaaeoa??ico c aeei?enoaiiyi aioeaaeoa??aeueieo i?aia?ao?a ia o?eueee i?ecaiaeeoue aei naiaoe?? NIO a?ae I?, aea ? aeaaioai?ii aieeaa? ia oa?aeoa? a?ioeaiico oianoi? eeoee, ui i?aeoaa?aeaeo?oueny ?acoeueoaoaie niinoa?aaeaiue a aeeiai?oe?. 8. ?aoeeaeea aae?eiaaeoa?ii? ?ioaeoe?? noi?iaiaeaeo?oueny iia??oaiiyi iieaciee?a a?ioeaiico eeoa/ieea, ui iaiao?aeii a?aoiaoaaoe i?e i?iaaaeaii? a?aaeeeaoe?eii? oa?ai??. I?AEOE*I? ?AEIIAIAeAOe?? 1. Aiaeineii?/ia ae?aaiinoeea aano?iaeoiaeaiaeueieo caoai?thaaiue o ae?oae iiaeiia ii?aeioaaoeny c aecia/aiiyi aae?eiaaeoa?ii? ?ioaeoe??. I?e oeueiio o?aaciee oano iiaea aooe aeei?enoaii eeoa ye i???ioiaiee (iiia?aaei?e). Ia?aaaao aa?oi a?aeaeaaaoe aaeoa??ieia?/iiio iaoiaeo ae?aaiinoeee I?-?ioaeoe??. ?ioi?iaoeai?noue ae?aaiinoeee c?inoa? i?e iaeii/aniiio aeei?enoaii? o?ueio iaoiae?a, i?ioa a i?aeoe/i?e ?iaio? oe?eeii aeinoaoiuei aeei?enoiaoaaoe iaeei ?c iaoiae?a, aea?? yeiai aecia/a?oueny nooiaiai ?iaaceaiino? oa iiaeeeainoyie e?eoaaeueiiai caeeaaeo. 2. sse aeiaeaoeia? ae?aaiinoe/i? ? i?iaiinoe/i? e?eoa??? OAAeI, anioe?eiaaii? c I?, o ae?oae iaiao?aeii aeei?enoiaoaaoe iieacieee a?ioeaiico oianoi? eeoee. 3. Aoaeoeaia e?eoaaiiy aano?iaioa?ieia?/ii? iaoieia??, anioe?eiaaii? c aae?eiaaeoa?iith ?ioaeoe??th, yea noi?iaiaeaeo?oueny aeenaaeoa??icii oianoi? eeoee, caaacia/o?oueny ni?eueiei canoinoaaiiyi aioeaaeoa??aeueii? oa i?ia?ioe/ii? oa?ai??. 4.An?i oai?ei ia i?ei?e/iee aae?eiaaeoa??ic ? c aoaeoeaiith a?aaeeeaoe??th /a?ac i?nyoeue i?ney cae?i/aiiy aioeaaeoa??aeueii? oa?ai??, iieacaii i?iaaaeaiiy a eaoaiiac? /a?ac 6-12 i?nyoe?a aiaeineii?/ii? oa ao?ieia?/ii? ae?aaiinoeee aae?eiaaeoa?ii? ?ioaeoe??, aeine?aeaeaiiy a?ioeaiico oianoi? eeoee, i?iaaaeaiiy i?e iaiao?aeiino? a?aaeeeaoe?eieo caoiae?a, ei?aeoe?? aeyaeaieo ii?ooaiue. NIENIE I?AOeUe, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1.Aia?iaa A.?. Ao?io?iiia oa?ai?y Helicobacter pylori oa a?ioeaiic eeoa/ieea. // Ee?i?/ia oa?iaoe?y.- 1998.-o.2, ?3.-N. 39-40. 2. Aia?iaa A.E., Aaeioniaa I.TH. Yoeio?iiiay oa?aiey o?iie/aneeo oaeeeiaaeoa?-annioeee?iaaiiuo caaieaaaiee i?aaiia aano?iaeoiaeaiaeueiie ciiu. // E?ee Oe?a?ie.- 1999.-?3.-N. 66. 3. Aia?iaa A.?., A?eioniaa I.TH. Oae?eioeei o eiiieaeni?e oa?ai?? i?ei?e/iiai oae?eiaaeoa??ico o ae?oae. // Ee?i?/ia oa?iaoe?y.- 1999.-o.3, ?1.- N.54-56. 4. Aia?iaa A.E. Ninoiyiea aeioeaiica eeoa/ieea i?e aaeeeiaaeoa? iiceoeaiie aano?iaeoiaeaiaeueiie iaoieiaee o aeaoae. // A?niee i?iaeai a?ieia?? ? iaaeeoeeie.- 1999.-?5.-N.-21-23. 5.Aia?iaa A.?. Ee?i?/ia cia/ou?noue aea/aiiy eeoeiaiai a?ioeaiico i?e o?ii?/ieo aano?iaeoiaeai?oao o ae?oae. // Iaae?ao??y, aeooa?noai oa a?iaeieia?y.- 1999.-?3.-N.18-19. 6. Aia?iaa A.E. Ninoiyiea iee?iaeioeaiica eeoa/ieea i?e o?iie/aneeo caaieaaaieyo aano?iaeoiaeaiaeueiie ciiu o aeaoae. // Oace aeii. iaoeiai-i?aeoe/ii? eiioa?aioe?? ii aeooaeueiei ieoaiiyi iaaeeoeeie. - Oa?e?a, 1998.-N.15-16. 7. Aia?iaa A.E. Ninoiyiea aeioeaiica eeoa/ieea i?e ieei?e/aneii oaeeeiaaeoa?eica o aeaoae. // Aeinyaiaiiy oa iaae??oaii? ieoaiiy aano?iaioa?ieia??: Ca. iaoe. i?. / ?inoeooo oa?ai?? AII Oe?a?ie. – Oa?e?a, 1998.- N.24. 8. Nieiaeiaie/aiei E.A., Aia?iaa A.E. Ioeaiea yooaeoeaiinoe aaeeeioeeia a eiiieaeniie oa?aiee ieei?e/aneiai aaeeeiaaeoa?eica o aeaoae. // Oac. aeieeaaeia IV ?inneeneie aano?iyioa?ieiae/aneie iaaeaee. - Iineaa, 1998.-N.58. 9.Aia?iaa A.E. Ioaeae?iiua ?acoeueoaou oa?aiee ieei?e/aneiai aaeeeiaaeoa?eica, nii?iaiaeaeathuaainy aeenaaeoa?eicii eeoa/ieea. // Aeooaeueiua i?iaeaiu aaaeiieiaeueiie iaoieiaee o aeaoae: Na. iao/. o?./ ?inneeneee ainoaea?noaaiiue oieaa?neoao. - Iineaa, 1999.-N.67-68. 10.Naaai A.I., Iaaeaiei I.A., Nieiaeiaie/aiei E.A., Aaicee A.A., Aia?iaa A.E. Yiaeineiie/aneay oa?aeoa?enoeea e y?aaeeeaoeeiiiay oa?aiey o?iie/aneie I?-annioeee?iaaiiuo caaieaaaiee aano?iaeoiaeaiaeueiie ciiu o aeaoae. // Aeooaeueiua i?iaeaiu aaaeiieiaeueiie iaoieiaee o aeaoae: Na. iao/. o?. / ?inneeneee ainoaea?noaaiiue oieaa?neoao. - Iineaa, 1999.-N.68-69. 11. Aia?iaa A.E. Yoeieiae/aneay aeeaaiinoeea ieei?e/aneiai oaeeeiaaeoa?eica o aeaoae. // Oace aeii. aano?iaioa?ieia?/iiai oeaeiy e?ea??a a?enueeiai-iia?o?yieo nee Oe?a?ie. – A?iieoey, 1998.-N.10. 12. Aia?iaa A.E. N?aaieoaeueiay yooaeoeaiinoue iaoiaeia aeeaaiinoeee oaeeeiaaeoa?iie eioaeoeee o aeaoae. // Oace aeii. III iaoeiai-i?aeoe/ii? eiioa?aioe?? aeeoy/eo aano?iaioa?ieia?a Oe?a?ie. – Iaeana, 1999.-N.67-68. o?ii?/iee aano?iaeoiaeai?o, aae?eiaaeoa?ia ?ioaeoe?y, a?ioeaiic oianoi? eeoee, aeenaaeoa??ic eeoa/ieeo, ae?aaiinoeea aae?eiaaeoa?ii? ?ioaeoe??, eiiieaenia oa?ai?y, i?ia?ioeee o?iie/aneee aano?iaeoiaeaieo, aaeeeiaaeoa?iay eioaeoeey, aeioeaiic oienoie eeoee, aeenaaeoa?eic eeoa/ieea, aeeaaiinoeea aaeeeiaaeoa?iie eioaeoeee, eiiieaenia oa?aiey, i?iaeioeee. nhronic gastroduodenites, helicobacter infection, intestinal biocenosis, intestinal disbacteriosis, diagnostica helicobacter infection, combined therapy, probiotices Aia?iaa A.?. Ee?ie/ia cia/ou?noue aea/aiiy a?ioeaiico oianoi? eeoee i?e o?ii?/ieo aae?eiaaeoa?-anioe?eiaaieo caoai?thaaiiyo i?aai?a aano?iaeoiaeaiaeueii? ciie o ae?oae. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca oaoii 14.01.10 - iaae?ao??y. Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Oa?e?a,1999. Ia i?aenoaa? io?eiaieo ?acoeueoao?a aeine?aeaeaiiy anoaiiaeee, ui /anoioa ?io?eiaaiino? I? i?e OAAeI o ae?oae neeaaea? 82,1%; aenieee nooi?iue ?io?eiaaiino? /ano?oa a?aecia/aany ia oii? aeano?oeoeaieo ci?i NIO oa AeIE, ia?inoaa i?iii?oe?eii o?eaaeino? aano?iaioa?ieia?/iiai aiaiiaco, a?eo aeeoeie. Ae?aaiinoeeo I? – ?ioaeoe?? i?iaiaeeee ca aeiiiiiaith o?aaciiai oanoo, aaeoa??ieia?/iiai aeine?aeaeaiiy oa ?A. O iaae?ao?e/i?e i?aeoeoe? oe?eeii aeinoaoiuei aeei?enoiaoaaoe iaeei c iaoiae?a, aea?? yeiai caeaaeeoue a?ae nooiaiy ?iaaceaiino? ? ni?iiiaeiino? e?eoaaeueiiai caeeaaeo. OAAeI o ae?oae o 100% aeiaaee?a noi?iaiaeaeoaaeany aeena?ioe/ieie ii?ooaiiyie oianoi? eeoee, ye? oa?aeoa?ecoaaeeny aeao?oeeoii aiaa?iaieo ? ye?nieie ci?iaie aa?iaieo i?e?ii?aai?ci?a. I?e OAAeI, anioe?eiaaii? c I?, o 62,3% ae?oae ae?aaiinoiaaii aeenaaeoa??ic oianoi? eeoee, yeee i?io?eaa a noaeiiiainiaai?e oi?i? ? noi?iaiaeaeoaaany ae?aaeaieie ee?i?/ieie i?iyaaie. Nooi?iue oyaeeino? aeena?ioe/ieo ii?ooaiue caeaaeaea a?ae iayaiino? aae?eiaaeoa?ii? ?ioaeoe??, oa?aeoa?o aiaeineii?/ieo ci?i neeciai? iaieiiee aano?iaeoiaeaiaeueii? ciie OAAeI, anioe?eiaaia c I?, o 80,4% aeiaaee?a noi?iaiaeaeoaaeany caiaeaiiyi neeciai? iaieiiee oianoi? eeoee. *anoioa ? ae?aci?noue aeena?ioe/ieo ii?ooaiue oianoi? eeoee i?e OAAeI, anioe?eiaaii? c I?, o ae?oae aecia/aea iaiao?aei?noue ii?aeiaii? oa?ai?? aae?eiaaeoa??ico ? aeenaaeoa??ico. Eiiieaenia oa?ai?y aae?eiaaeoa??ico c aeei?enoaiiyi aioeaaeoa??aeueieo i?aia?ao?a ? i?ia?ioe/ii? oa?ai?? ia o?eueee i?ecaiaeeea aei naiaoe?? NIO a?ae I?, aea ? aeaaioai?ii aieeaaea ia oa?aeoa? a?ioeaiico oianoi? eeoee, ui i?aeoaa?aeaeoaaeiny ?acoeueoaoaie niinoa?aaeaiue a aeeiai?oe?. ?aoeeaeea OAAeI ? aae?eiaaeoa?ii? ?ioaeoe?? noi?iaiaeaeoaaany iia??oaiiyi iieaciee?a a?ioeaiico eeoa/ieea, ui iaiao?aeii a?aoiaoaaoe i?e i?iaaaeaii? a?aaeeeaoe?eii? oa?ai??. EETH*IA? NEIAA: o?ii?/iee aano?iaeoiaeai?o, aae?eiaaeoa?ia ?ioaeoe?y, a?ioeaiic oianoi? eeoee, aeenaaeoa??ic eeoa/ieeo, ae?aaiinoeea aae?eiaaeoa?ii? ?ioaeoe??, eiiieaenia oa?ai?y, i?ia?ioeee.. Aia?iaa A.E. Eeeie/aneay cia/eiinoue eco/aiey aeioeaiica oienoie eeoee i?e o?iie/aneeo aaeeeiaaeoa? - annioeee?iaaiiuo caaieaaaieyo i?aaiia aano?iaeoiaeaiaeueiie ciiu o aeaoae.- ?oeiienue. Aeenna?oaoeey ia nieneaiea o/?iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.10 - iaaeeao?ey. Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, Oa?ueeia, 1999. Aeena?oaoeeiiiay ?aaioa iinayuaia eco/aieth aeeyiey aioeaaeoa?eaeueiie oa?aiee ieei?e/aneiai aaeeeiaaeoa?eica ia ninoiyiea aeioeaiica oienoie eeoee i?e OAAeI o aeaoae. ?ac?aaioaiu aeeooa?aioee?iaaiiua ?aeiiaiaeaoeee ii ea/aieth ni/aoaiiie iaoieiaee (aaeeeiaaeoa?eic e aeenaaeoa?eic). ?aaioa iniiaaia ia n?aaieoaeueiii aiaeeca ?acoeueoaoia eeeieei-eaai?aoi?ii-eino?oiaioaeueiuo enneaaeiaaiee aeaoae n OAAeI, annioeee?iaaiiie e iaannioeee?iaaiiie n I?. I?iaaaeaii iaeiia?aiaiiia enneaaeiaaiea aaeoa?eaeueiie oei?u aio?aeueiiai ioaeaea aeaeoaeea e eeoa/iie iee?ioei?u, /oi iicaieeei ?anoe?eoue i?aaenoaaeaiea i iaoiaaiaoe/aneeo iaoaieciao eioeoee?iaaiey, iiauneoue ea/anoai aeeaaiinoeee e ea/aiey OAAeI. Onoaiiaeaia /anoioa eioeoee?iaaiey I? i?e OAAeI o aeaoae – 82,1% neo/aaa; aunieay noaiaiue eioeoee?iaaiey /aua ioia/aia ia oiia aeano?oeoeaiuo eciaiaiee NIAE e AeIE n ia?inoaieai i?iii?oeeiiaeueii aic?anoo aeaoae e aeeeoaeueiinoe aano?iyioa?ieiae/aneiai aiaiiaca. Aeeaaiinoeeo I?- eioaeoeee inouanoaeyee n iiiiuueth o?aaciiai oanoa, aaeoa?eieiae/aneiai enneaaeiaaiey e ?A. O?aaciue oano ?anniao?eaaeny eeoue a ea/anoaa i?aaeaa?eoaeueiiai iaoiaea enneaaeiaaiey. Eioi?iaoeaiinoue aeeaaiinoeee I?-eioaeoeee aic?inoaea i?e iaeiia?aiaiiii eniieueciaaiee o??o iaoiaeia, iaeiaei a iaaeeao?e/aneie i?aeoeea aiieia aeinoaoi/ii eniieueciaaiea iaeiiai ec iaoiaeia, auai? eioi?iai ii?aaeaeyaony noaiaiueth eiaaceaiinoe e aiciiaeiinoyie ea/aaiiai o/?aaeaeaiey. Eco/aiu iniaaiiinoe eeeie/aneeo i?iyaeaiee, oa/aiea e oyaeanoue OAAeI, annioeee?iaaiiie n I?, o aeaoae a caaeneiinoe io ninoiyiey aeioeaiica oienoie eeoee. OAAeI o aeaoae a 100% neo/aaa nii?iaiaeaeaeanue aeenaeioe/aneeie ia?ooaieyie oienoie eeoee, eioi?ua oa?aeoa?eciaaeenue aeaoeoeeoii aiay?iaiiai eiiiiiaioa e ea/anoaaiiuie eciaiaieyie ay?iaiiai. Noaiaiue oyaeanoe aeenaeioe/aneeo ia?ooaiee iaoiaeeeanue a caaeneiinoe io iaee/ey aaeeeiaaeoa?iie eioaeoeee, oa?aeoa?a yiaeineiie/aneeo eciaiaiee NIAE e AeIE. Cia/eoaeueiua (III noaiaiue oyaeanoe) aeenaeioe/aneea ia?ooaiee oienoie eeoee i?e OAAeI, annioeee?iaaiiie n I?, yaeeenue einaaiiui iiaeoaa?aeaeaieai aeeeoaeueiie ia?nenoaioeee I?, ii?aaeaeyee ino?ioo iaoieiae/aneiai i?ioeanna, a oaeaea aeoaeio ii?aaeaiey NIAE e AeIE. O 62,3% aeaoae n OAAeI, annioeee?iaaiiie n I?, aeeaaiinoe?iaaee aeenaaeoa?eic oienoie eeoee, eioi?ue i?ioaeae a noaeiiiaine?iaaiiie oi?ia e oa?aeoa?eciaaeny au?aaeaiiuie eeeie/aneeie i?iyaeaieyie. O 80,4% aeaoae n eeeie/aneeie i?iyaeaieyie aeenaaeoa?eica oienoie eeoee (ii aeaiui ?aeoi?iiaiineiiee e e??eaia?aoee) ?aaeno?e?iaaee ainiaeeoaeueiua eciaiaiey neecenoie iaiei/ee oienoie eeoee, /oi ioyaiuaei oa/aiea OAAeI e o?aaiaaei ei??aeoeee auyaeaiiuo ia?ooaiee. Ia iniiaaiee eniieueciaaiey iieacaoaeae aeioeaiica oienoie eeoee ?ac?aaioaiu e?eoa?ee i?iaiice?iaaiey aeaeueiaeoaai oa/aiey aaeeeiaaeoa?-annioeee?iaaiiuo caaieaaaiee o aeaoae e eiaeeaeaeoaeecaoeee ea/aaii-i?ioeeaeoe/aneeo ia?ii?eyoee. Auyaeaiiua ia?ooaiey ninoaaa iee?ioei?u aeaeoaeea, oienoie eeoee, y?iceaii-ycaaiiua eciaiaiey NIAE e AeIE yaeeenue iieacaieai e iacia/aieth ni/aoaiiie aioeaaeoa?eaeueiie e i?iaeioe/aneie oa?aiee aaeeeiaaeoa? annioeee?iaaiiuo caaieaaaiee o aeaoae. I?eiaiaiea a eiiieaeniie oa?aiee aaeeeiaaeoa?eica aioeaaeoa?eaeueiuo i?aia?aoia yaeeinue aaconeiaiui iieacaieai e ?aiiaio iacia/aieth i?iaeioeeia. Eiiieaeniay oa?aiey aaeeeiaaeoa?eica n eniieueciaaieai aioeaaeoa?eaeueiuo n?aaenoa e i?iaeioe/aneie oa?aiee ia oieueei i?eaiaeeea e naiaoeee NIAE io I?, ii e aeaaioai?ii aeeyea ia oa?aeoa? aeioeaiica oienoie eeoee, /oi iiaeoaa?aeaeaeinue ?acoeueoaoaie iaaethaeaiee a aeeiaieea. ?aoeeaeea OAAeI e aaeeeiaaeoa?iie eioaeoeee nii?iaiaeaeaeny oooaeoaieai iieacaoaeae aeioeaiica eeoa/ieea, /oi iaiaoiaeeii o/eouaaoue i?e i?iaaaeaiee y?aaeeeaoeeiiiie oa?aiee. Eeth/aaua neiaa: o?iie/aneee aano?iaeoiaeaieo, aaeeeiaaeoa?iay eioaeoeey, aeioeaiic oienoie eeoee, aeenaaeoa?eic eeoa/ieea, aeeaaiinoeea aaeeeiaaeoa?iie eioaeoeee, eiiieaenia oa?aiey, i?iaeioeee. Aobrova V.I. Clinical significance of study of intestines biocenosis in children with chronic diseases of gastroduodenal area assococited with helicobacter infection.- Manuscript. Thesis for the degree of candidate of medical science in speciality of 14.01.10 - pediatrics. Kharkiv State Medical University, Kharkiv, 2000. Obtained results have shown that chronic gastroduodenal pathology in children is associated with Helicobacter pylori infection in 82.1% of cases. High level of Hp infection more often is present in patients with superficial lesions of gastric and duodenal mucosa and correlate with the duration of the disease. Helicobacter infection diagnostica was made with the help of ureatic test bacteriologic study and reaction of an agglutination. One method is completely sufficient for etiologic diagnosis in pediatric practice. Chronic gastroduodenal pathology in children is accompanied with large bowel intestinal disbacteriosis in 100% of cases. It is characterized by the deficiency of anaerobe component and qualitative changes of aerobe microorganisms. Its severity depends on the presence of Hp infection and character of endoscopic lesions of gastroduodenal mucosa. Its course lasts in subcompensated form and is accompanied with large bowel inflammation in 80.4% of cases. The rate and severity of large bowel intestinal disbacteriosis in children with Hp associated gastroduodenitis define the necessity of combined therapy of Hp infection and disbacteriosis. Combined therapy of Hp infection with the prescription of both antibiotic agents and probiotic remedies not only eliminates Hp but favourable influence on the character of the intestinal biocenosis. This fact was confirmed during follow-up of children. Recurrence of Hp infection is accompanied by disturbances of intestinal biocenosis. It is necessary to take into consideration this fact during Hp elimination and therefore prescribe probiotic agents as well. Key words: Chronic gastroduodenites, helicobacter infection, intestinal biocenosis, intestinal disbacteriosis, diagnostica helicobacter infection, combined therapy, probiotices.

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