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Гомеостаз магнію при есенціальній гіпертензії (клініко-фізіологічна характеристика, патофізіологія, гормональна регуляція, корекція порушень, обгрунту

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Aeaaeai?y iaaee/ieo iaoe Oe?a?ie

?inoeooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea

Aia?iaa Ieaia Aieiaeeie??aia

OAeE: 616.12-008.331.1:612

AIIAINOAC IAAIITH I?E ANAIOeIAEUeIIE A?IA?OAICI?

(ee?i?ei-o?c?ieia?/ia oa?aeoa?enoeea, iaoio?c?ieia?y, ai?iiiaeueia
?aaoeyoe?y, ei?aeoe?y ii?ooaiue, iaa?oiooaaiiy aeai?o

aioea?ia?oaiceaii? oa?ai??)

14.01.11 – ea?ae?ieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

aeieoi?a iaaee/ieo iaoe

Ee?a – 1999

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a ?inoeooo? ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea AII
Oe?a?ie ? Aeiiaoeueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? ?i.
I.Ai?ueeiai IIC Oe?a?ie.

Iaoeiaee eiinoeueoaio:

aeieoi? iaaee/ieo iaoe EIEII??OeUe A?eoi??y Aieiaeeie??aia,
Aeiiaoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao ?i. I.Ai?ueeiai IIC
Oe?a?ie, i?ioani? eaoaae?e aioo??oi?o oai?ia ?2).

Io?oe?ei? iiiiaioe:

– Aeieoi? iaaee/ieo iaoe, Aeaaeai?e AII Oe?a?ie, i?ioani? AeCssE Aai?a?e
A?eoi?iae/, Aei?i?iiao?ianueea iaaee/ia aeaaeai?y IIC Oe?a?ie,
caa?aeoaa/ eaoaae?e aini?oaeueii? oa?ai?? ?2.

– Aeieoi? iaaee/ieo iaoe, Aeaaeai?e AII Oe?a?ie, *eai-ei?. IAI Oe?a?ie ?
AII ?in??, i?ioani? EI?EOOEI Ieaa Aaneeueiae/, ?inoeooo aa?iioieia?? AII
Oe?a?ie, ea??aiee a?aeae?eo ee?i?/ii? o?c?ieia?? oa iaoieia?? aioo??oi?o
i?aai?a.

– Aeieoi? iaaee/ieo iaoe, i?ioani? OIEA? Aiaoie?e Aieiaeeie?iae/,
Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe ?i.I.E.Ooieea IIC
Oe?a?ie, caa?aeoaa/ eaoaae?e aa?iioieia?? ? aa??ao???.

I?ia?aeia onoaiiaa: Iaoe?iiaeueiee iaaee/iee oi?aa?neoao
?i.I.I.Aiaiiieueoey IIC Oe?a?ie, eaoaae?a oa?ai?? noiiaoieia?/iiai
oaeoeueoaoo (i.Ee?a).

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 14 ” aa?aniy 1999 ?. i “ 12 ”
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.616.01
?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea AII Oe?a?ie (252151,
Ee?a, aoe. Ia?iaeiiai Iiie/aiiy, 5)

C aeena?oaoe??th iiaeia iciaeiieoeny a a?ae?ioaoe? ?inoeoooo
ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea AII Oe?a?ie ca aae?anith (252151
Ee?a, aoe. Ia?iaeiiai Iiie/aiiy, 5).

Aaoi?aoa?ao ?ic?neaiee “12” na?iiy 1999 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee Aeaye N.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. A?oa??aeueia a?ia?oaic?y (AA) ? iaeiei c naieo
?iciianthaeaeaieo o na?o? caoai?thaaiue: 15-30 % aei?ineiai ianaeaiiy
iathoue i?aeaeuaiee a?oa??aeueiee oene (AO) [?.I. Naeuaiei 1997; ?.I.
Nie?iiaa ? ni?aaao., 1997, 1998; A.A. Aecye, O.A. Eieaniee, 1998].
Iaoiaaii?noue AA caiaaeoi aeniea – AA ? i?ia?aeiei oaeoi?ii ?eceeo
?oai?/ii? oai?iae na?oey, iiceiaiai ?inoeueoo, na?oeaai? iaaeinoaoiino?,
oiaoi iniiaieo i?e/ei ?iaae?aeiino? ? nia?oiino? [O.TH. Iaea?aae/, 1997;
?.A. Na?a??i?, 1997; A.A. Aecye, O.A. Eieaniee, 1998; ?.I. Nie?iiaa ?
ni?aaao., 1998]. A Oe?a?i? aeniea ?iciianthaeaeai?noue AA na?aae
ianaeaiiy ca inoaii? 5 ?ie?a noi?iaiaeaeo?oueny c?inoaiiyi ia?aeiii?
?iaae?aeiino? aiane?aeie AA iaa?oue o 3 ?ace ? nia?oiino?, iia’ycaiii? c
AA, o 1,7 ?ace. O ca’yceo c oeei i?iaeaia AA ia? nioe?aeueia cia/aiiy ?
? iaoe?iiaeueiith [?.I. Naeuaiei, 1997; ?.I. Nie?iiaa ? ni?aaao., 1997,
1998; A.A. Oiea? ? ni?aaao., 1998]. Ia aeaeue, ia aeeaey/enue ia
iayai?noue aaeeeiai a?naiaeo aioea?ia?oaiceaieo i?aia?ao?a, ?o aea??
caeeoa?oueny a iniiaiiio aii??e/iei, a aoaeoeai?noue aioea?ia?oaiceaii?
oa?iaeioa?ai?? iaaeinoaoiueith, ui iio?aao? ooi/iaiiy ? iaoiaaiaoe/iiai
iaa?oiooaaiiy iieacaiue aeey ?? i?iaaaeaiiy [A.I. Aia?ia, I.E, AEa??iia
1998; A.A. Eieii??oeue ? ni?aaao., 1998].

A?aeiii, ui a a?eueoino? aeiaaee?a a iniia? anaioe?aeueii? a?ia?oaic??
(AA) eaaeeoue i?aeaeuaiiy oiiono aeaaeeeo i’yc?a noaeei. Noaeeiiee oiion
aecia/a?oueny aaeainii i?ae oaeoi?aie ?aeaenaoe?? ? eiino?eeoe??.
Ana?aaeei? aeaaeeii’yciai? ee?oeie noaeeie oa o ea?ae?ii?ioeeo? ?iie
iaai?th aa?ooue o/anoue o ii?aeiaii? i?ioean?a caoaeaeaiiy – nei?i/aiiy
– ?icneaaeaiiy. Aeao?oeeo aioo??oiueiee?oeiiiai iaai?th, ui ? i?e?iaeiei
aioaaii?noii eaeueoe?th, i?eaiaeeoue aei aacieiino?eeoe??, ca yeo ?
a?aeiia?aeaeueiee eaeueoe?e, ? i?aeaeuo? /ooeea?noue a?oa??e aei
aacii?ani??a. [E.N. Nayoia, A.I. Oeeia, 1996; A.L. Tranquilli et al.,
1992; M.J. Picado et al., 1993; ?. Laurant, A. Berthelot, 1994]. O
aeine?aeaeaiiyo B.M. Altura, B.T. Altura et al. (1995), M. Kawai et al.
(1996); Wester ?. (1995) aoei aeiaaaeaii, ui a iaoe??io?a ?c AA
niinoa??aa?oueny cieaeaiiy eiioeaio?aoe?? iaai?th a oeeoiieaci? ee?oei,
ui, o naith /a?ao, aaaea aei i?aeaeuaiiy oiiono noaeei ? i?aeaeuaiiy
??aiy AO. Iaeiae ia ?nio? iaeiicia/ii? aeoiee i?i aieea iaai?th ia
??aaiue AO. Iacaaaeath/e ia yaiee aieea aino?eo ii?ooaiue iaai??i?? ia
??aaiue AO, ca’ycie i?ae ieaciaiiith ? aioo??oiueiee?oeiiith
eiioeaio?aoe??th iaai?th, eiai ae??oe/iei niiaeeaaiiyi ? ie?eiaith
aene?aoe??th c iaei??? noi?iie ? ??aiai AO, c ?ioi? iaaaaaoi iaioa
ae?aciee ? i?inoaaeo?oueny ia caaaeaee. Ia?i?aeueiee i?eeii iaai?th a
aeic? 15 ? 20 iiieue/24 aiaeeie ia aeyaeya aeiaeaoeiaiai a?iioaiceaiiai
aoaeoo [E. Miyagawa et al.,1992]. Aeyaeai? i?e AA ??ci? ci?ie iieaciee?a
iaoaaie?cio iaai?th iaea?aeothoue ??cia o?aeooaaiiy ? ia ae?iaeaii
?aeeiiai oyaeaiiy i?i oa, /e iathoue aiie iaoio?c?ieia?/ia cia/aiiy a
?icaeoeo AA ?, ioaea, ?oiy ei?aeoe?y iiaea ni?eyoe ia?aeii?e ? aoi?eii?e
i?io?eaeoeoe? aai aiie i?inoi noi?iaiaeaeothoue i?aeaeuaiiy AO ? ia
aeiaaathoue ei?aeoe??. Ii?ooaiiyi iaoaaie?cio iaai?th a iaoiaaiac? AA
i?eae?ey?oueny iacaneoaeaii iaea ?ieue, ui caiaeeoueny, a iniiaiiio,
o?eueee aei o/ano? ?ii?a iaai?th o aioo??oiueiee?oeiieo i?ioeanao
nei?i/aiiy aeaaeeeo i’yc?a noaeei. Iaaiee ai?no iaai?th ona?aaeei?
ee?oei caaacia/o?oueny ceaaiaeaeaiei ooieoe?eiioaaiiyi on?o eaiie
iaoaaie?cio iaai?th (eeoeiaa aani?aoe?y, ie?eiaa aene?aoe?y, o?ainii?o
iaai?th iii?ae iicaee?oeiiith ??aeeiith, e?noeaie ? ee?oeiaie). Noai
iaoaaie?cio iaai?th a i?aai?ci?, eiai ?aaoeyoe?y, ui iaoiiaeththoue
c?ooaiiy aioo??oiueiee?oeiiiai ai?noo ?ii?a iaai?th ?, a?aeiia?aeii,
?oiueiai ooieoe?iiaeueiiai cia/aiiy, aieea ia iueiai aioea?ia?oaiceaii?
oa?iaeioa?ai?? aea/aiee iaiiaii, a ?acoeueoaoe noia?a/eea?, oi/a naia
aieea ia ciai?oi?e aaeain iaai?th iiaea i?eaanoe aei ei?aeoe?? ii?ooaiue
eiai iaoaaie?cio, i?aeo?eiaiiy aiiainoaco ? i?aeaeuaiiy aoaeoeaiino?
e?eoaaiiy AA.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa
aeeiioaaeany a?aeiia?aeii aei iniiaieo ieai?a IAe? ?inoeoooo
ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea, aoaeo/e o?aaiaioii oaie
“?ic?iaeoe ? ai?iaaaeeoe a i?aeoeeo ioi?iie caei?ia’y oaoiieia??
i?io?eaeoeee ? e?eoaaiiy a?oa??aeueii? a?ia?oaic?? ca aeiiiiiaith
iia?oi?o aioea?ia?oaiceaieo cania?a ? iaiaaeeeaiaioicieo iaoiae?a
e?eoaaiiy (? Aea?ae?a?no?aoe?? 0198O004009)” ? Aeiiaoeueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, aoaeo/e o?aaiaioii oaie “?ic?iaea
iaoiae?a ?aiiuei? ae?aaiinoeee ? oa?iaeieia?/ii? ei?aeoe?? ii?ooaiue
iaoai?ci?a ?aaoeyoe?? ?ci?ii??, ?ciaieai?? ? ?cioii?? i?e a?oa??aeuei?e
a?ia?oaic?? ? o?ii?/i?e na?oeaa?e iaaeinoaoiino?” (? Aea?ae?a?no?aoe??
0197V018403).

Iaoa ? caaea/? aeine?aeaeaiiy. Iniiaiith iaoith aeine?aeaeaiiy aoei
aea/aiiy noaio aiiainoaco iaai?th i?e AA aeey ?icoi?iiy iaoai?ci?a
?icaeoeo AA, ?ic?iaee iioeiaeueieo iaoiae?a ei?aeoe?? ii?ooaiue
iaoaaie?cio iaai?th, iaa?oiooaaiiy e?eoa???a aeai?o oa i?aeaeuaiiy
aoaeoeaiino? aioea?ia?oaiceaii? oa?ai?? (AAO) aeey iioei?caoe??
i?iaaaeaiiy i?io?eaeoeee AA. A?aeiia?aeii aei oeueiai aoee
noi?ioeueiaai? ianooii? caaea/?:

1. Ioe?ieoe noai iaoaaie?cio iaai?th i?e ??cieo noaae?yo AA ? aecia/eoe
iaoie?iaoe/io ?ieue ii?ooaiue iaoaaie?cio iaai?th aeey ?icoi?iiy
iaoai?ci?a noaiiaeaiiy ? noaa?e?caoe?? AA.

2. Aeine?aeeoe noai ai?iiiaeueii? ?aaoeyoe?? iaoaaie?cio iaai?th ca
aeiiiiiaith niaoeeo?/ieo ai?iii?a – ia?aoai?iiia (IOA), eaeueoeeoii?ia
(EO), ai?iiiaeueii-aeoeaiiai iaoaaie?oo (a?oai?ia Ae3) a oiiaao
iaaaioaaeoaaeueieo oano?a ?c nieyie iaai?th, ae?o?aoeeaie ? c
?aaoethth/eie ai?iiiaie.

3. Aea/eoe noai an?o naeoi??a iaoaaie?cio iaai?th o oai?eo ia AA oeyoii
aecia/aiiy ciai?oiueiee?oeiiiai, aioo??oiueiee?oeiiiai ai?noo, eeoeiai?
aani?aoe?? oa iaai?eo?aoe/ii? ooieoe?? ie?ie a oiiaao iaai??aeo
iaaaioaaeaiue.

4. Aeine?aeeoe o oai?eo ia AA ?ioaineai?noue o?ainii?oo iaai?th i?ae
ie?eiaei oa e?noeiaei naeoi?aie.

5. ?ic?iaeoe aaeaeaaoi? iaoiaee ioe?iee noaio iaoaaie?cio iaai?th aeey
ee?i?/ii? i?aeoeee (oaeaee?noue ae?i?iaoe?? iaaaioaaeoaaeueii? iaai??i??
(OAIMg++), eeoeiai? aani?aoe?? iaai?th).

6. Iaa?oiooaaoe e?eoa??? aeai?o aioea?ia?oaiceaieo i?aia?ao?a a
caeaaeiino? a?ae noaio iaoaaie?cio iaai?th o oai?eo ia AA.

7. Cai?iiiioaaoe iioeiaeuei? iaoiaee ei?aeoe?? ii?ooaiue iaoaaie?cio
iaai?th o oai?eo ia AA.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa ia i?aenoaa?
i?iaaaeaiiai eiiieaeniiai iaii?aiiiai aeine?aeaeaiiy noaio iaoaaie?cio
iaai?th i?e AA: aecia/aia iaoie?iaoe/ia ?ieue eiai ii?ooaiue aeey
oi?ioaaiiy ? ?icaeoeo AA; aecia/aiee noai ai?iiiaeueii? ?aaoeyoe??
iaoaaie?cio iaai?th o oai?eo ia AA ca aeiiiiiaith IOA, EO ?
ai?iiiaeueiiaeoeaiiai iaoaaie?oo a?oai?ia Ae3 a oiiaao
iaaaioaaeoaaeueieo oano?a ?c nieyie iaai?th ? ?aaoethth/eie ai?iiiaie;
aea/aii noai ? ?ieue ii?ooaiue eeoeiai? aani?aoe?? iaai?th o oai?eo ia
AA ca aeiiiiiaith ?ic?iaeaiiai iaie ia?i?aeueiiai ? aioo??oiueiaaiiiai
iaaaioaaeoaaeueiiai oanoo; ioe?iaii noai iaai?eo?aoe/ii? ooieoe?? ie?ie
? ?ieue ?? ?iceaae?a o ?icaeoeo AA; c’yniaaii o oai?eo ia AA
ni?yiiaai?noue ie?eiaiai o?ainii?oo ia oo?eiaiiy eaeueoe?th oeyoii
ia?aaaaeiiai aeaaaeaiiy iaai?th; ?ic?iaeai? aaeaeaaoi? iaoiaee ioe?iee
noaio iaoaaie?cio iaai?th aeey ee?i?/ii? i?aeoeee (oaeaee?noue
ae?i?iaoe?? iaaaioaaeoaaeueii? iaai??i??, eeoeiaa aani?aoe?y iaai?th); a
caeaaeiino? a?ae noaio iaoaaie?cio iaai?th o oai?eo ia AA iaa?oioiaai?
e?eoa??? aeai?o AAO; aecia/ai? iaoiaee ei?aeoe?? ii?ooaiue iaoaaie?cio
iaai?th o oai?eo ia AA.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. ?ic?iaeaii iaoiae
aecia/aiiy eeoeiai? aani?aoe?? iaai?th a ee?i?oe?. Aecia/aii oa?aeoa?
ni?aa?aeiioaiiy ie?eiaiai o?ainii?oo iaai?th ? eaeueoe?th ? aecia/aia
?ioaineai?noue o?ainii?oo iaai?th i?ae iicaee?oeiiei ? e?noeiaei
naeoi?ii o oai?eo ia AA. ?ic?iaeai? aaeaeaaoi? iaoiaee ioe?iee noaio
iaoaaie?cio iaai?th a ee?i?/i?e i?aeoeoe? ? cai?iiiiiaai? iioeiaeuei?
iaoiaee ei?aeoe?? ii?ooaiue iaoaaie?cio iaai?th o oai?eo ia AA.
Aecia/aia caeaaei?noue oa?ai?? ?ia?a?oi?aie aia?ioaicei-ia?aoai?thth/iai
oa?iaioo (AIO), aioaaii?noaie eaeueoe?th, aaoa-aae?aiiaeieaoi?aie oa
ae?o?aoeeaie a?ae noaio iaoaaie?cio iaai?th o oai?eo ia AA oa
iaa?oioiaai? e?eoa??? aeai?o AAO.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy a i?aeoeeo. Iaoa??aee
aeena?oaoe?eii? ?iaioe a?aeia?aaeai? a iaoiaee/ieo ?aeiiaiaeaoe?yo
“No/ani? i?eioeeie e?eoaaiiy a?oa??aeueii? a?ia?oaic?? (Ee?a, 1997), o
Iaoaio? ? 2079129 ia aeiao?ae: “Niin?a ae?aaiinoeee eaoaioii? oi?ie
o?ii?/iiai i??eiiao?eoo o oai?eo ?c a?ia?oaiceaiei neiae?iiii aac
noiooi?o o?ieia?/ieo caoai?thaaiue” (iaoaioiaeaniee Oe?IAe? ea?ae?ieia??
?i. aeaae. I.Ae.No?aaeanea) o ni?aaaoi?noa?, aeaeaiee Eii?oaoii
?in?enueei? Oaaea?aoe?? ii iaoaioao ? oiaa?ieo ciaeao (?iniaoaio)
10.05.97 ? i’youeio ?aoe?iiae?caoi?nueeeo i?iiiceoe?yo o ni?aaaoi?noa?,
caoaa?aeaeaieo Aeiiaoeueeei iaaee/iei oi?aa?neoaoii: ?aoei?iiiceoe?y
?5742 “Niin?a i?aeaeuaiiy aioea?ia?oaiceaii? aoaeoeaiino? ?ia?a?oi??a
aia?ioaicei-ia?aoai?thth/iai oa?iaioo a in?a ?c aenieei ??aiai
aeoeaiino? ?ai?io ieacie” (1996); ?aoei?iiiceoe?y ?5743 “Niin?a
i?aeaeuaiiy aioea?ia?oaiceaii? aoaeoeaiino? ?ia?a?oi??a
aia?ioaicei-ia?aoai?thth/iai oa?iaioo a in?a ?c iecueeei ? ii?iaeueiei
??aiai aeoeaiino? ?ai?io ieacie” (1996); ?aoei?iiiceoe?y ?5744 “Niin?a
i?aeaeuaiiy aioea?ia?oaiceaii? aoaeoeaiino? aioaaii?no?a eaeueoe?th a
in?a ?c aenieei ??aiai aeoeaiino? ?ai?io ieacie” (1996); ?aoei?iiiceoe?y
?5745 “Niin?a i?aeaeuaiiy aioea?ia?oaiceaii? aoaeoeaiino? aioaaii?no?a
eaeueoe?th a in?a ?c iecueeei ? ii?iaeueiei ??aiai aeoeaiino? ?ai?io
ieacie” (1996); ?aoei?iiiceoe?y ?5754 “Niin?a iioei?caoe?? ae??oe ?10
aeey oai?eo a?ia?oii?/iith oai?iaith oeyoii ei?aeoe?? niiaeeaaiiy
iaai?th a ae??o?” (1996).

?acoeueoaoe aeine?aeaeaiue ? iaoiaee/i? ?aeiiaiaeaoe?? ai?iaaaeaeai? ?
aeei?enoiaothoueny c iiceoeaiei nioe?aeueii-aeiiii?/iei ?
e?eoaaeueii-i?io?eaeoe/iei aoaeoii o ea?ae?ieia?/ieo ? oa?aiaaoe/ieo
a?aeae?eaiiyo iaeanieo ? i?nueeeo e?ea?aiue Caii??aeaey, Oa?eiaa,
Aei?i?iiao?ianueea, Aeiiaoeueea, Eoaainueea, A?iieoe?, Iaeane, Eueaiaa,
Oa?iiiiey, ?aaii-O?aie?anueea. ?acoeueoaoe aeena?oaoe?eii? ?iaioe
ai?iaaaeaeai? a iaa/aeueiee i?ioean eaoaae? oa?ai?? ? ea?ae?ieia??
Ee?anueei? iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E.Ooieea,
Iaoe?iiaeueiiai iaaee/iiai oi?aa?neoaoo ?i. I.I.Aiaiiieueoea (Ee?a),
Aei?i?iiao?ianueei? iaaee/ii? aeaaeai??, Aeiiaoeueeiai iaaee/iiai
oi?aa?neoaoo ?i.I.Ai?ueeiai, Eoaainueeiai iaaee/iiai oi?aa?neoaoo,
Caii??cueeiai ?inoeoooo oaeineiiaeaiiy e?ea??a, Euea?anueeiai iaaee/iiai
oi?aa?neoaoo, ?aaii-O?aie?anueei? iaaee/ii? aeaaeai??, Oa?iii?euenueeiai
iaaee/iiai oi?aa?neoaoo ?i.?.ss.Ai?aa/aanueeiai, ui i?aeoaa?aeaeo?oueny
aeoaie ai?iaaaeaeaiiy.

Iniaenoee aianie caeiaoaa/a. Aeena?oaoe?eia ?iaioa ? naiino?eiei
iaoeiaei aeine?aeaeaiiyi. Aaoi?o iaeaaeeoue ?aeay nenoaiiiai aea/aiiy
noaio iaoaaie?cio iaai?th i?e AA (o?aeoe?eiee neeaae iaai?th a e?ia?,
iaai?eo?aoe/ia ooieoe?y ie?ie, eeoeiaa aani?aoe?y iaai?th, ae??oe/ia
niiaeeaaiiy, eiioeaio?aoe?y iaai?th a a?eo?ioeeoao, o?ainii?o iaai?th
i?ae iicaee?oeiiith ??aeeiith ? e?noeaie, ai?iiiaeueia ?aaoeyoe?y
iaoaaie?cio iaai?th a oiiaao iaaaioaaeoaaeuei?o oano?a c nieyie iaai?th,
c ?aaoethth/eie ai?iiiaie (IOA, a?oai?i Ae3), c ae?o?aoeeaie. Aaoi?ii
i?iaaaeaiee aiae?c ?acoeueoao?a aeine?aeaeaiiy o oai?eo ia AA, a oaeiae
aeeiiaiee aiae?c ni?aa?aeiioaiiy ie?eiaiai o?ainii?oo eaeueoe?th ?
iaai?th i?e AA. Caeiaoaa/ naiino?eii ?ic?iaeea i?ia?aio aeine?aeaeaiiy,
aeeiiaea a?aea?? oaiaoe/ieo oai?eo, ?ic?iaeea aaeaeaaoi? iaoiaee ioe?iee
noaio iaoaaie?cio iaai?th, aeinooii? a ee?i?/i?e i?aeoeoe? (OAIMg++,
eeoeiaa aani?aoe?y iaai?th) oa aecia/eea e?eoa??? aeai?o AAO a
caeaaeiino? a?ae noaio iaoaaie?cio iaai?th. Aiae?c oa ocaaaeueiaiiy
?acoeueoao?a, noaoenoe/ia ii?aoethaaiiy iaoa??aeo, i?aeaioiaea
iiiia?ao??, iaeyaeiaeo oa i?ea?iaeueieo noaoae, ioi?ieaiiy
aeena?oaoe?eii? ?iaioe oa aaoi?aoa?aoo cae?eniai? caeiaoaa/ai
naiino?eii.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aena?oeai? ? iaaiai?thaaeenue ia 1-io Iaoe?iiaeueiiio c’?cae?
oa?iaeieia?a Oe?a?ie (Iieoaaa, 1995), 2-e I?aeia?iaei?e eiioa?aioe??
caei?iaiai na?oey (Aa?naeiia, ?niai?y, 1995), 7-e ?a?iiaenuee?e
eiioa?aioe?? ii oa?/oaaiith (A?aeaiue, Aano??y, 1995), 23-io eiia?an?
I?aeia?iaeiiai oiaa?enoaa ii aioo??oi?e iaaeeoeei? (Iai?ea, O?e?i?ie,
1996), c’?cae? ea?ae?ieia?a Iieaeiae (Eeoei?a, Iieaeiaa, 1996), 1-io
Eiia?an? anioe?aoe?? ea?ae?ieia?a e?a?i NIAe (Iineaa, 1997), 3-io
eiia?an? anioe?aoe?? ea?ae?ieia?a e?a?i Na?aaeiuei? Ac?? (Oaoeaio,
Ocaaeenoai, 1997), 5-io eiia?an? ea?ae?ieia?a Oe?a?ie (Ee?a, 1997), 7-io
I?aeia?iaeiiio neiiic?oi? ii na?oeaai-noaeeii?e oa?iaeioa?ai??
(???onae?i, ?c?a?eue, 1997), 16-io I?ai?/iiio eiia?an? ea?ae?ieia?a
(Oaiia?a, O?ieyiae?y, 1997), 8-e ?a?iiaenuee?e eiioa?aioe?? ii
a?ia?oaic?? (I?eai, ?oae?y, 1997), 4-e i?aeia?iaei?e eiioa?aioe?? ii
i?aaaioeai?e ea?ae?ieia?? (Iii?aaeue, Eaiaaea, 1997), 1-io
I?aeia?iaeiiio eiia?an? Iieuenueeiai ea?ae?ieia?/iiai oiaa?enoaa
(Aa?oaaa, Iieueua, 1997), 2-e eiioa?aioe?? e?a?i
I?aaeaiii-Oeoiieaainueeiai ?aa?iio ii a?ia?oaic?? (Iai?ea, O?e?i?ie,
1997), 5-e I?aeia?iaei?e eiioa?aioe?? ii ea?ae?ieia?? (A?aoe, Aano??y,
1997), 1-io eiia?an? ii aioo??oi?e iaaeeoeei? (Iaano??oo, I?aea?eaiaee,
1997), 13-e Anana?oi?e eiioa?aioe?? Oaaea?aoe?? ? oiaa?enoaa
ea?ae?ieia?a (??i aea AEaiae?i, A?acee?y, 1998), 13-io Iaoeiaiio
neiiic?oi? Aia?eeainueeiai oiaa?enoaa ii a?ia?oaic?? (Iueth Ei?e, NOA,
1998), 17-io Iaoeiaiio neiiic?oi? i?aeia?iaeiiai oiaa?enoaa ii
a?ia?oaic?? (Ainoa?aeai, I?aea?eaiaee, 1998), 14-io c’?cae? oa?aiaao?a
Oe?a?ie (Ee?a, 1998), ?anioae?eainuee?e iaoeiai-i?aeoe/i?e eiioa?aioe??
“A?oa??aeueia a?ia?oaic?y oa a?e” (Ee?a, 1998), 1-io
?ioa?iaoe?iiaeueiiio eiia?an? ii na?oeaaeo oai?iaao (Aaoeiaoii, NOA,
1999), 9-e ?a?iiaenuee?e eiioa?aioe?? ii a?ia?oaic?? (I?eai, ?oae?y,
1999).

Aeena?oaoe?eio ?iaioo ?icaeyiooi ? ?aeiiaiaeiaaii aei caoenoo ia
iaoeia?e eiioa?aioe?? ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea
(1999) oa ia iaoeia?e eiioa?aioe?? ni?eueii c can?aeaiiyi Ai?iaaoe?eii?
?aaee ?inoeoooo ea?ae?ieia?? ?i. aeaae. I.Ae.No?aaeanea AII Oe?a?ie
(1999 ?.).

Ioae?eaoe??. Iaoa??aee aeena?oaoe?eii? ?iaioe aena?oeai? a iiiia?ao??
“Anaioe?aeueia a?ia?oaic?y ? aiiainoac eaeueoe?th” (E., *aoaa?oa oaeey,
1998.-195 n.- ae. 5, 6, 7, 8) oa 70 iioae?eiaaieo ?iaioao, o oiio /ene?
naiino?eieo – 16. Na?aae ieo noaoo? a iaoeiaeo aeo?iaeao – 14 (c ieo 5
naiino?eieo), iaoaio -1 (o ni?aaaoi?noa?), aeiiia?ae? ia c’?caeao – 23,
8 noaoae o ca??ieeao iaoeiaeo i?aoeue, 21 oac aeiiia?aeae ia iaoeiaeo ?
iaoeiai-i?aeoe/ieo eiioa?aioe?yo. Ca ei?aeiiii iioae?eiaaii 38 iaoeiaeo
i?aoeue.

Ia’?i ? no?oeoo?a ?iaioe. ?iaioa iaienaia ia 344 noi??ieao
iaoeiiieniiai oaenoo, neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, 6
?icae?e?a aeanieo aeine?aeaeaiue, caeeth/aiiy, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e. ?ethno?iaaia 49 oaaeeoeyie ? 28 iaethieaie. Nienie
aeei?enoaii? e?oa?aoo?e aeeth/a? 591 aeaea?ae, na?aae yeeo 90
a?o/eciyieo ? 501 ?iicaiieo aaoi??a.

INIIAIEE CI?NO ?IAIOE

Iaoa??ae ? iaoiaee aeine?aeaeaiiy. Ianoaaeaii 348 oai?eo, ?c eio?eo 267
oai?eo ia AA o a?oe? a?ae 30 aei 55 ?ie?a (159 /ieia?e?a ? 108 ae?iie).
O 32 oai?eo aeyaeaia AA I noaae??, o 207 – II noaae?? oa o 28 – III
noaae?? (ii eeaneo?eaoe?? AIIC). Na?aaei?e a?e neeaa 46.8±1.3 ?ieo.
O?eaae?noue ae?aaiinoiaaiiai caoai?thaaiiy eieeaaeany a?ae 2-o aei 18
?ie?a. ??aaiue nenoie?/iiai AO eieeaaany a?ae 140 aei 226 ii ?o. no.,
neeaaeath/e a na?aaeiueiio 182,8±5,3 ii ?o. no. ??aaiue ae?anoie?/iiai
AO eieeaaany a?ae 96 aei 126 ii ?o. no., neeaaeath/e a na?aaeiueiio
108,2±3,2 ii ?o.no. O /anoeie oai?eo ia AA i?iaaaeaia aeiaiaa
iii?oi?oaaiiy AO ca ?aeiiaiaeaoe??th oao?aoe?a ?in?enueeiai
iaoeiai-ae?iaie/iai eiiieaeno IIC ?O (A.A. A?aa?aeca, I.TH. Aoueeia,
1997). Ianoaaeaiiy, e??i caaaeueiiee?i?/iiai, o?ceeaeueiiai,
eaai?aoi?iiai oa ?ino?oiaioaeueiiai, aeeth/aei ?yae oano?a aeey
aeeeth/aiiy neiioiiaoe/ieo a?ia?oaic?e. Aeey aeeoa?aioe?aeueii?
ae?aaiinoeee i?ae neiioiiaoe/iith oa anaioe?aeueiith a?ia?oaic??th ie
ei?enooaaeenue niaoe?aeueiith i?ia?aiith ianoaaeaiiy oai?eo ia AA,
cai?iiiiiaaio a ?inoeooo? ea?ae?ieia?? ?i. I.E. Iynieeiaa AIEOe.
Ianoaaeaii 70 caei?iaeo in?a (eiio?ieueia a?oia c ii?iaeueiei ??aiai AO)
aac iciae caoai?thaaiue na?oeaai-noaeeiii? nenoaie, ie?ie,
oeoieiai-eeoeiaiai o?aeoo ? e?noeiai? nenoaie i?ae /an ianoaaeaiiy aai a
ieioeiio. A?e ianoaaeaieo eiio?ieueii? a?oie neeaaeaa 25-56 ?ie?a,
na?aaei?e a?e 44.0±1.4 ?iee. Aaeeea /anoeia caei?iaeo ? oai?eo ia AA
in?a aoea ianoaaeaia iaiaeii?aciai a i?ioean? oa?iaeioa?ai?? AA ?
iaaaioaaeoaaeueieo oano?a. E??i oiai, ianoaaeaii 11 oai?eo ?c
neiioiiaoe/iith ie?eiaith a?ia?oaic??th o a?oe? a?ae 28 aei 52 ?ie?a,
na?aaei?e a?e 41.1±1.5 ?iee. ?iciiae?e ianoaaeaieo ca iicieia?/ieie
oi?iaie, a?eii, noaooth i?aaenoaaeaiee o oaae. 1.

E?eoaaiiy oai?eo i?iaiaeeee ?ia?a?oi?aie AIO, aioaaii?noaie eaeueoe?th,
aaoa-aae?aiiaeieaoi?aie, ae?o?aoeeaie. Aoaeoeai?noue e?eoaaiiy aaaaeaee
aenieith, yeui aiia aeinyaaeany iiiioa?ai??th i?aia?aoii o na?aaei?e
aeic?, na?aaeiuei? – o aenie?e aeic?, ieceith – o aenie?e aeic? oa o
eiia?iaoe?? c ?ioeie aioea?ia?oaiceaieie i?aia?aoaie.

An? ianoaaeaiiy i?iaiaeeee i?ney 5-7 aeaiii? ia?a?ae a i?eeii?
aioea?ia?oaiceaieo i?aia?ao?a. Oai?? a ia??iae ianoaaeaiiy iaea?aeoaaee
noaiaea?oio ae??oo N 10 ii Iaacia?o, ca yeith a i?aai?ci iaaeoiaeeoue ca
aeiao a?ey 14 iiieue iaai?th, 16,5 iiieue eaeueoe?th, 90 iiieue iao??th,
70 iiieue eae?th, 80 a a?eea, 70 a aee?o, 400 a aoaeaaiae?a.
Iaaaioaaeoaaeuei? oanoe i?iaiaeeee iaoua ?aieii /a?ac 16 aiaeei i?ney
inoaiiueiai i?eeiio ?ae?. O?eaae?noue oa?iaeioa?ai?? neeaaeaea a?ae 3
aei 6 i?nyoe?a.

Ianoaaeaiiy oai?eo aeeth/aei aea/aiiy noaio iaoaaie?cio iaai?th c
oa?aeoa?enoeeith eiaeiiai eiai naeoi?a, ye? cae?eniththoue ye eiai
ciai?oi?e aaeain (ae??oe/ia niiaeeaaiiy, eeoeiao aani?aoe?th, ie?eiao
aene?aoe?th), oae ? caaacia/othoue aioo??oith ??aiiaaao (iaai??i?th,
aioo??oiueiee?oeiiee ai?no iaai?th a a?eo?ioeeoao, o?ainii?o i?ae on?ia
naeoi?aie, aeeth/ath/e iai?i i?ae iicaee?oeiiith ??aeeiith, e?noeaie ?
ie?eaie, aioo??oiueiie?eiaee o?ainii?o), a oaeiae ai?iiiaeueio
?aaoeyoe?th iaoaaie?cio iaai?th niaoeeo?/ieie ai?iiiaie – IOA, EO,
ai?iiiaeueii-aeoeaiei iaoaaie?oii a?oai?io Ae3 –
1,25-ae?a?ae?ien?oieaeaeueoeeoa?ieii (1,25(OH)2Ae3).

Oaaeeoey 1

?iciiae?e ianoaaeaieo oai?eo a?oa??aeueiith a?ia?oaic??th

ca iicieia?/ieie oi?iaie, a?eii ? noaooth

Iicieia?/ia oi?iaA?e (?iee) ? noaoueAnueiaina?aaei?e

a?eaei 30 30-3940-4950-60/ae/ae/ae/aeAA I noaae??73144-4–3246.81.3AA II
noaae??4228169014712820746.81.3AA III noaae??–11139-42846.81.3Oai??
neiioiiaoe/iith ie?eiaith
a?ia?oaic??th–2333–1142.11.5Caei?ia?72131417152-7044.01.4Anueiai187584
811378141234844.31.4

Aeey oa?aeoa?enoeee iaai??i?? aecia/aee caaaeueio eiioeaio?aoe?th
iaai?th a ne?iaaooe? e?ia? iaoiaeii aoiiii-aani?aoe?eii?
niaeo?ioioiiao??? ia niaeo?ioioiiao?? “Naoo?i-3” ? eiioeaio?aoe?th
?ii?ciaaii? o?aeoe?? iaai?th iaoiaeii i?yii? iioaioe?iiao??? c
aeei?enoaiiyi ?iiinaeaeoeaiiai eaeueoe?e-iaai??aiai aeaeo?iaea,
aeaioiaeaiiai a Naieo-Iaoa?ao?cueeiio oi?aa?neoao?.

Ie?eiaee o?ainii?o iaai?th ioe?ithaaee oeyoii aea/aiiy aene?aoe??
iaai?th, eiai ee??aino, o?eueo?aoe?eiiai ca?yaeo (OC) ? aene?aoiaaii?
o?aeoe?? (AO), aecia/aee ae?o?ac ? oaeaee?noue eeoai/eiai? o?eueo?aoe??
(OEO). Iaai?eo?aoe/io ooieoe?th ie?ie ioe?ithaaee a cae/aeieo oiiaao
(aeiaiaa aene?aoe?y iaai?th; ee??ain-aeine?aeaeaiiy i?e iii??iiio
aioeae?o?ac?) ? a oiiaao iaaaioaaeaiue (aioo??oiueiaaiiee, ia?i?aeueiee
? iiaea?eiee iaai?eoiea?aioiee oano (IOO); aeciaaiia aaaaeaiiy IOA,
ia?i?aeueiee i?eeii ieneaeaa?oa (aiaeiaa a?oai?io Ae, ui ia? oi?ioeo
1-a-IIAe3 ? iaoaaie?co?oueny a ia/?ioe? a 1,25(OH)2Ae3). Ioe?ithaaee
oaeiae eaeueoe?eo?aoe/io ? iao??eo?aoe/io ooieoe?th ie?ie.
Eiioeaio?aoe?th iaai?th ? eaeueoe?th a na/? aecia/aee ca aeiiiiiaith
aoiiii-aani?aoe?eii? niaeo?ioioiiao???. Eiioeaio?aoe?th iao??th a e?ia?
? na/? aecia/aee ia iieoi’yiiio oioiiao?? “Oeaenn-3”.

Aioo??oiueiee?oeiio eiioeaio?aoe?th iaai?th aei??thaaee a a?eo?ioeeoao
ca aeiiiiiaith aoiiii-aani?aoe?eii? niaeo?ioioiiao??? i?ney a?aeae?eaiiy
? iaoai?/ii? ?oeiaoe?? a?eo?ioeeoa?ii? iane.

Eeoeiao aani?aoe?th iaai?th oa?aeoa?ecoaaee ca aeiiiiiaith
ia?i?aeueiiai ? aioo??oiueiaaiiiai iaaaioaaeaiiy nieyie iaai?th,
ioe?ithth/e aeeiai?eo iaai??i?? /a?ac 120 oa.i?ney ia?i?aeueiiai ?
aioo??oiueiaaiiiai iaaaioaaeaiiy n?eeth iaai?th a aeic? 0,1 iiieue ia 1
ea iane o?ea.

C iaoith ioe?iee aeiaiaiai niiaeeaaiiy iaai?th aeei?enoiaoaaee: 1)
noaiaea?oio aieaoo i?i niiaeeaaiiy i?iaeoeo?a oa?/oaaiiy ca 24 aiaeeie
ca aeiiiiiaith ioeyae?a aioiaeo i?iaeoeo?a ? aethae ?c ianooiiei
?ic?aooieii ai?noo a ae??o? iaai?th; 2) aecia/aiiy ie?eiai? aene?aoe??
iaai?th, eaeueoe?th ? iao??th a aeiaia?e na/?.

Noai o?ainii?oo iaai?th i?ae iicaee?oeiiith ??aeeiith ? e?noeaie
oa?aeoa?ecoaaee, aecia/ath/e iaaeoiaeaeaiiy iaai?th c e?noee a ieacio
e?ia? ca iaoiaeii ?.I.??iaeiai? (1987).

Eiioeaio?aoe?th ai?iii?a o ne?iaaooe? e?ia? aei??thaaee ?aae?i?ioiiei
iaoiaeii ca aeiiiiiaith iaai??a “Malinkrodt diagnostica” (IOA), “Ria-mat
calcitonin-II” (EO), “Bullmann” (1,25(OH)2Ae3).

Aeey aaeaeaaoii? oa?aeoa?enoeee noaio iaoaaie?cio iaai?th
aeei?enoiaoaaee IOO, ui aeicaiey? iaea?aeaoe eiai ocaaaeueiaio
e?euee?nio oa?aeoa?enoeeo ia ??ai? i?aai?cio, aeniei aeioeoeueiee ?
/ooeeaee aei ii??aiyii iaaaeeeeo c?ooaiue. Aioo??oiueiaaiiee IOO
i?iaiaeeee oeyoii aioo??oiueiaaiiiai aaaaeaiiy 0,1 iiieue iaai?th
noeueoaoo ia 1 ea iane o?ea. E?ia ?c aaie a?aee aei aaaaeaiiy noeueoaoo
iaai?th, /a?ac 20 ? 150 oaeeei i?ney eiai aaaaeaiiy. I?e i?iaaaeaii?
ia?i?aeueiiai IOO i?ney acyooy e?ia? c e?eoueiai? aaie ethaeeia, yea
ianoaaeo?oueny, i?eeiaea ia?i?aeueii ania?eai ?c ?ic?aooieo 0,1 iiieue
iaai?th ia ea iane o?ea, caieaath/e eiai 100 ie aeenoeeueiaaii? aiaee.
??aaiue iaai??i?? aecia/aee /a?ac 120 ? 240 oaeeei.

E??i iieaciee?a aacaeueiiai noaio iaoaaie?cio iaai?th, aea/aee aieea ia
ieo aino?eo ? o?ii?/ieo iaaaioaaeaiue (aioo??oiueiaaiiiai ?
ia?i?aeueiiai IOO, o oiio /ene? iiaea?eieo, ?c i?ieiiaiaaiei
iaaaioaaeaiiyi nieyie iaai?th, ai?iiiaie – IOA (aioo??i’ycaaa aaaaeaiiy
0,5 IAe ia?aoe?ai?aeeio ia 1 ea iane o?ea) ? 1,25(OH)2Ae3 (ia?i?aeueiee
o?eaeaiiee i?eeii ieneaeaa?oo iaeei ?ac ia aeiao a aeic? 1 iea),
aioea?ia?oaiceaieie oa?iaeieia?/ieie i?aia?aoaie.

Noai oeaio?aeueii? aaiiaeeiai?ee ? ia?eoa?e/iiai e?iaioieo ioe?ithaaee
ca aeiiiiiaith AoiEA ? ieethc?eii? ieaoeciia?ao?? a ia??iae niieith,
i?ney i?eeiio aioea?ia?oaiceaieo oa?iaeii?aia?ao?a, nieae iaai?th ? a
oiiaao o?ce/iiai iaaaioaaeaiiy ia aaeia?aiiao??.

Ee?i?/ia aeine?aeaeaiiy c ei?aeoe??th ii?ooaiue iaoaaie?cio iaai?th
i?iaaaeaii o oai?eo “i’yeith” ? “iii??iith?” a?ia?oaic??th
(ae?anoie?/iee AO a iaaeao 95-114 ii ?o. no.) c ioe?ieith ae??oe/iiai
aeiaiaiai niiaeeaaiiy iaai?th aaciina?aaeiuei ia?aae ? i?ney 3-
i?ny/iiai uiaeaiiiai i?eeiio ania?eaia a aeiaia?e aeic? 0,10 iiieue/ea
iane o?ea.

?acoeueoaoe aeine?aeaeaiiy.

Aiiainoac iaai?th i?e anaioe?aeuei?e a?ia?oaic?? (iaoio?c?ieia?y
iaoaaie?cio iaai?th). O oai?eo ia AA i? eiioeaio?aoe?y ?ii?ciaaiiai
iaai?th, i? eiai caaaeueia eiioeaio?aoe?y ?noioii ia a?ae??ciythoueny
a?ae iieaciee?a o caei?iaeo ianoaaeaieo eiio?ieueii? a?oie (oaae. 2). O
oai?eo ia AA ?c ??ciei ??aiai AO ae?aaeai? ?icoiaeaeaiiy a ??ai?
?ii?ciaaii? eiioeaio?aoe?? iaai?th a?aenooi?. Iaeiae o oai?eo ?c aenieei
noaa?eueiei ??aiai ae?anoie?/iiai AO, ui ia?aaeuo? 115 ii ?o. no.,
eiioeaio?aoe?y ?ii?ciaaiiai iaai?th a 86% aeiaaee?a ia ia?aaeuo? ??aaiue
ieaeiuei? eaa?oee? (0,50 iiieue/e) ? a aeiaeiiai oai?iai c aenieith AA
eiioeaio?aoe?y ?ii?ciaaiiai iaai?th ia aeinyaa? ??aiy aa?oiuei?
eaa?oee?.

Iaie ia aeyaeaii aeinoia??ii? caeaaeiino? ??aiy iaai??i?? a?ae a?eo. O
oai?eo ?c III no. caoai?thaaiiy eiioeaio?aoe?y ?ii?ciaaiiai iaai?th ia?
oaiaeaioe?th aei cieaeaiiy. Oaeei /eiii, eiioeaio?aoe?y iaai?th a
ne?iaaooe? e?ia? oai?eo ia AA i?aeo?eio?oueny i?aeoe/ii a ii?iaeueieo
iaaeao. Oea oe?eeii c?icoi?ei, yeui a?aooaaoe, ui cia/i? a?aeoeeaiiy
eiioeaio?aoe?? iicaee?oeiiiai iaai?th na?ae/aoue i?i aeeaie?
ooeiaeaeaiiy a nenoai? ?aaoeyoe?? aiiainoaco iaai?th, ui, i/aaeaeii, ia
ia? i?noey i?e AA.

O caei?iaeo ianoaaeaieo eiioeaio?aoe?y iaai?th a a?eo?ioeeoao neeaea
1,37-1,69, o na?aaeiueiio 1,52±0,02 iiieue/e, o oai?eo ia AA – 0,96-1,81
iiieue/e, o na?aaeiueiio 1,38±0,02 iiieue/e, oiaoi noaoenoe/ii
aeinoia??ii iaioa, i?ae o caei?iaeo ianoaaeaieo (p

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