I?i?noa?noai ioi?iie caei?ia’y Oe?a?ie

?aaii-O?aie?anueea aea?aeaaia iaaee/ia aeaaeai?y

OAeE 616. 36-002. 2:576. 8. 097. 29

OOOE?IA Ienaia Nayoineaa?aia

AIAeIAAIIA ?IOIENEEAOe?ss, NOAI I?E?IA?IOeAIICO OA AeAssEEO OAEOI??A
?IOI?OAOO O OAI?EO IA O?II?*I? AeEOOCI? CAOAI?THAAIIss IA*?IEE

14.01.02. — aioo??oi? oai?iae

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

?aaii-O?aie?anuee — 1999

Aeena?oaoei?th ? ?oeiien

Aeena?oaoe?y aeeiiaia a Aoeiaeinuee?e aea?aeaai?e iaaee/i?e aeaaeai?? oa
IAe? iaaeeei-aeieia?/ieo i?iaeai (i.*a?i?aoe?), IIC Oe?a?ie

Iaoeiaee ea??aiee:

aeieoi? iaaee/ieo iaoe, i?ioani? Eieiii?oeue Ieoaeei TH?ieiae/,

Aoeiaeinueea aea?aeaaia iaaee/ia aeaaeaiiy, caa?aeoaa/ eaoaae?e
aini?oaeueii? oa?ai?? oa ee?i?/ii? oa?iaeieia??

Io?oe?ei? iiiiaioe:

aeieoi? iaaee/ieo iaoe, i?ioani? Iaeei Aaneeue ?aaaiiae/,
Iaaii-O?aieianueea aea?aeaaia iaaee/ia aeaaeaiiy, caaiaeoaa/ eaoaae?e
i?iiaaeaaoeee aioo?ioiio oai?ia

aeieoi? iaaee/ieo iaoe, i?ioani? Aiioiia Aaeeia Aiaoiei?aia,

Ee?anueea iaaee/ia aeaaeaiiy iineyaeeieiiii? inaioe, i?ioani? eaoaae?e
aano?iaioa?ieiai? oa ae??oioa?ai??

I?iaiaeia onoaiiaa — Iinoeooo oa?aii? AII Oe?a?ie (i. Oa?eia) IIC
Oe?a?ie, a?aeae?e aano?iaioa?ieia??

Caoeno aeena?oaoe?? a?aeaoaeaoueny «__18_» aa?aciy 1999 ?ieo i __12___
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 20.601.01
?aaii-O?aie?anueei? aea?-aeaaii? iaaee/ii? aeaaeai?? (284000,
i.?aaii-O?aie?anuee, aoe.Aaeeoeueea, 2).

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? ?aaii-O?aie?anueei?
aea?aeaaii? iaaee/ii? aeaaeai?? ca aae?anith: i.?aaii-O?aie?anuee,
aoe.Aaeeoeueea, 7.

Aaoi?aoa?ao ?ic?neaiee «__17__» ethoiai 1999 ?ieo.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee,

aeieoi? iaaee/ieo iaoe, i?ioani? I.A. I?ei/ae

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOECAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie

O?ii?/i? aeeooci? caoai?thaaiiy ia/?iee (OAeCI) ? iaeieie c iaea?eueo
?iciianthaeaeaieo caoai?thaaiue aaiaoia?e?a?ii? nenoaie
(C.A.Ai?in?ia,1996; A.N. Eia?iia, 1998; N.Ae.Iiaeeiiaa,1998).
Oaiaeaioe?y aei ca?eueoaiiy caoai?thaaiino? ia OAeCI na?aae in?a
i?aoeacaeaoiiai a?eo, ia?aaaaeii i?ia?anoth/ee ia?aa?a, /ano?
oneeaaeiaiiy, cia/ia ?iaae?aeecaoe?y oa nia?oi?noue iaoiiaeththoue
aaeeea nioe?aeueii-aeiiii?/ia cia/aiiy oe??? i?iaeaie (C.A.Ai?in?ia,
1996; I.ss.Aaaae,1998; A.O.?aaoe?i, 1997; A.A.N??ia,1997).

Nai?/ania ae?aaiinoeea OAeCI, i?iaiicoaaiiy ?o ia?aa?ao oa aea??
?aoe?iiaeueii? oaeoeee e?eoaaiiy caeeoathoueny neeaaeieie caaaeaiiyie ?
iio?aaothoue iiaeaeueoiai oaeineiiaeaiiy (A.A.Aiio?ia ?c ni?aaao.,1998;
I.ss.Aaaae, 1998; S.Sher-lok, 1996). Ca aeaieie e?oa?aoo?e, o 40-60%
iaoe??io?a o?ii?/ia iaoieia?y ia/?iee iia’ycaia ?c ia?aianaiei aino?ei
a??oniei aaiaoeoii A oa N, o 20-30% — ?c ceiaaeeaaiiyi aeeiaieai, o
30-40% ia? i?noea ci?oaiee aaiac (I.Neaeeaa, A.I.Iao?oiy, 1998).

O iaoiaaiac? OAeCI nooo?aa cia/aiiy iathoue ?ioii? ii?ooaiiy
(C.A.Ai?in?ia, A.A.N??ia, 1998; N.Ae.Iiaeeiiaa ?c ni?aaao., 1998;
I.ss.Naiaiaey?aa, 1997), aeoeaa-oe?y i?ioean?a a?eueii?aaeeeaeueiiai
ieeniaiiy e?i?ae?a oa a?iiie?ia??a (A?IEA) ia oii? cieaeaiiy aeoeaiino?
nenoai aioe?aaeeeaeueiiai caoenoo (A?C) (A.N.Eia?iia, A.I.Iaothoei,
1997; I.Ae.Iiae?eue/ae, 1996; E.E.Na?aaoeueeee ?c ni?aaao., 1998;
I.I.Neaeoi, 1997).

Anoaiiaeaia ?ieue aeenaaeoa??ico oianoi? eeoee a i?ia?anoaaii? oa
?icaeoeo oneeaaeiaiue OAeCI (A.A.Aiio?ia ?c ni?aaao., 1998;
I.A.Oiaeinaae/, 1997; ?.I.*a?aae, 1998).

Iniaeeaa i?noea na?aae ee?i?/ieo i?iya?a OAeCI caeia? neiae?ii
aiaeiaaiii? ?ioieneeaoe??, yeee coiiaeaiee, ia?o ca ana, ii?ooaiiyi
aeaoieneeoth/i? ooieoe?? ia/?iee (N.Ae.Iiaeeiiaa, 1997; I.TH.sseiae?a,
1993). I?iaeai? aiaeioieneeico i?e OAeCI i?enay/ai? iiiaeeiie? ?iaioe,
ye? aena?oeththoue ieoaiiy ae?aaiinoeee oa e?eoaaiiy oeueiai neiae?iio
eeoa i?e ia/?ieia?e ii?oinenoaii?e aioeaoaeiiao?? (?.I.Iaeei, 1997;
C.I.Ieoiee, 1998; A.I.Aiaiiieia ?c ni?aaao., 1997; I.I.sseoaianeee,
1997; H.O.Corn, 1993; P.Ferenci et al., 1996). Iaeiae iniaeeaino?
aeiee?i?/ieo oi?i aiaeioieneeico o oai?eo ia OAeCI a caeaaeiino? a?ae
aa??aioo ee?i?/iiai ia?aa?ao caoai?thaaiiy caeeoathoueny iaaeinoaoiuei
aea/aieie. Oea coiiaeth? aeioe?euei?noue iiaeaeueoiai iiooeo /?oeeo
ae?aaiinoe/ieo ia?ea??a neiae?iio aiaeiaaiii? ?ioieneeaoe?? i?e OAeCI,
?ic?iaee eeaneo?eaoe?? aiaeioieneeico ca nooiaiyie aaaeeino?,
aeine?aeaeaiiy ?ioaineaiino? i?ioean?a A?IEA, noaio i?ioe?aaeeeaeueieo
nenoai, ci?i ?ioii?aaeoeaiino? oa ai?noo i?e?iaeaiaio?a i?e OAeCI a
caeaaeiino? a?ae nooiaiy aaaeeino? aiaeioieneeico, ui ni?eyoeia
nenoaiaoecaoe?? ie?aieo iaoiaaiaoe/ieo eaiie a oe?e?nio nenoaio,
?ic?iaoe? iiaeo i?aeoiae?a aei aeeoa?aioe?eiaaiiai, iaoiaaiaoe/ii
iaa?oiooaaiiai e?eoaaiiy.

Anoaiiaeaii aca?iica’ycie ci?i aooioei?e oe??e c? noaiii caaaeueii?
?aaeoea-iino? i?aai?cio (I.A.?aaiia, 1989; I.I.Eeaiia?nueea,
A.A.Oaeueiiaa, 1966; A.A.Oaiaea?ia, 1998). I?ioa iaoeiaeo aeaieo i?i
ae?aaiinoe/ia oa i?iaiinoe/ia cia/aiiy noaio aooiooiiii? oa aeeiooiiii?
i?e?ioei?e oe??e i?e OAeCI iaia?.

A Oe?a?i? neioaciaaiee iiaee i?aia?ao o?io?eacie?i ?c aioeieneaeaioieie,
oeeoii?ioaeoi?ieie aeanoeainoyie (A.I. Aeaianueeee ?c ni?aaao., 1994;
A.Ae.A?c??, 1994; N.I.Ae?iaiaic ?c ni?aaao, 1995). ? iia?aeiieaiiy i?i
eiai aoaeoeai?noue i?e OAeCI ??ciiai aaiaco (I.N.Ieaieoeueea, 1996;
A.A.Neeoeia ?c ni?aaao., 1994; ?.I.Oaa/oe, 1998). Iaeiae aieea oeueiai
i?aia?aoo ia ?ioaineai?noue i?iya?a neiae?iio aiaeiaaiii? ?ioieneeaoe??,
iieacieee ee??aino aiaeiaaiieo oienei?a, noai caaaeueii?
?ioii?aaeoeaiino? oa i?e?iaeieia?? oe??e o oai?eo ia OAeCI ia
aeine?aeaeoaaany. A?aenooi? oaeiae a?aeiiino? i?i iniaeeaino?
i?ecia/aiiy o?io?eacie?io o oai?eo ia OAeCI a caeaaeiino? a?ae nooiaiy
aaaeeino? aiaeioieneeico.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie

Aeena?oaoe?eia ?iaioa aeeiiaia o a?aeiia?aeiino? c ieaiii
iaoeiai-aeine?aeieo ?ia?o Aoeiaeinueei? aea?aeaaii? iaaee/ii? aeaaeai??,
caoaa?aeaeaiei IIC Oe?a?ie, ? ? o?aaiaioii ieaiiai? iaoeiai? ?iaioe
eaoaae?e aini?oaeueii? oa?ai?? ? ee?i?/ii? oa?iaeieia?? ia oaio:
«A?eueii?aaeeeaeueia ieeniaiiy, iaoaaie?/i? ci?ie oa iniaee-aino?
iaoai?ci?a eiiiainaoe?? oa aeaeiiiainaoe?? i?e aeayeeo caoai?thaaiiyo
nenoaie o?aaeaiiy, oeeoiiai?/ieo noaiao ia Aoeiaei? oa iaa?oiooaaiiy
aeeoa?aioe?eiaaiiai e?eoaaiiy, ?aaa?e?oaoe??, i?io?eaeoeee» (iiia?
aea?aeaaii? ?a?no?aoe?? 0196V006738).

Iaoa aeineiaeaeaiiy: anoaiiaeoe ?ieue aiaeioieneeico a iaoiaaiac?
i?ia?ano-aaiiy o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee oa eiai
ni?aa?aeiioaiiy c ?ioai-neai?noth i?ioean?a ia?ieneaeiiai ieeniaiiy
e?i?ae?a, noaiii nenoai i?ioe-?aaeeeaeueiiai caoenoo, ?ioiiei noaoonii
i?aai?cio, aeaeiaei oa e?euee?niei neeaaeii aooioei?e oe??e,
i?e?iaeaiaioiei caaacia/aiiyi i?aai?cio, iaa?oiooaaoe niiniae ei?aeoe??
aeyaeaieo ii?ooaiue, oaeineiiaeeoe iaoiaeeeo aeeoa?aioe?eiaaiiai
e?eoaaiiy.

Iniiai? caaaeaiiy aeine?aeaeaiiy:

1.Aea/eoe ?ioaineai?noue aiaeioieneeico i?e o?ii?/ieo aeeoocieo
caoai?th-aaiiyo ia/?iee a caeaaeiino? a?ae aa??aioo ee?i?/iiai ia?aa?ao
caoai?thaaiiy.

2.Aea/eoe ?ioaineai?noue i?ioean?a a?eueii?aaeeeaeueiiai ieeniaiiy
e?i?ae?a oa noai caoenieo i?ioe?aaeeeaeueieo nenoai i?e o?ii?/ieo
aeeoocieo caoai?thaaiiyo ia/?iee a caeaaeiino? a?ae aa??aioo ee?i?/iiai
ia?aa?ao caoai?thaaiiy oa nooiaiy aaaeeino? aiaeioieneeico.

3.Aea/eoe noai aeayeeo iieaciee?a nenoaie ?ioi?oaoo oa ianiaoeeo?/ii?
?acenoaioiino? i?aai?cio i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee
a caeaaeiino? a?ae ia?aa?ao caoai?thaaiiy oa ?ioaineaiino? i?iya?a
neiae?iio aiaeiaaiii? ?ioieneeaoe??.

4.Aeine?aeeoe i?e?ia?ioeaiic iiaa?oiaaeo oa aeeaieeo oa??a oe??e o
oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee a ??ci? ia??iaee
caoai?thaaiiy, anoaii-aeoe aca?iica’ycie i?ae noaiii aooioei?e oe??e ?
noaiii ?ioii?aaeoeaiino? i?aai?cio.

5.Aeine?aeeoe ai?no i?e?iaeaiaio?a: eiaaeueoo, oeeieo, ia?aaioeth,
i?ae?, naeioeth, i?eaeth, cae?ca oa eaaei?th — o e?ia? oai?eo ia
o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee a caeaaeiino? a?ae nooiaiy
aaaeeino? aiaeioieneeico oa iieaciee?a ?ioiiiai noaoono.

6.Aea/eoe aieea o?io?eacie?io ia i?iyae neiae?iio aiaeiaaiii?
?ioieneeaoe??, ee?i?/i?, ?ioii? oa iaoaaie?/i? iieacieee o oai?eo ia
o?ii?/i? aeeooci? caoai?th-aaiiy ia/?iee.

7.Aecia/eoe ee?i?ei-eaai?aoi?i? e?eoa??? aei aeeoa?aioe?eiaaiiai
i?ecia/aiiy o?io?eacie?io a caeaaeiino? a?ae nooiaiy aiaeioieneeico a
eiiieaeni?e oa?ai?? oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a

1.Aia?oa ia iniia? eiiieaeniiai aeine?aeaeaiiy ia?ea??a aiaeioieneeico
anoaiiaeaii iniaeeaino? aiaeiaaiii? ?ioieneeaoe?? i?e ??cieo oi?iao
o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee.

2.Aia?oa iaaaaeaii ee?i?ei-iaoiaaiaoe/i? ia?aeae? i?ae ?ioaineai?noth
i?ioean?a ia?ieneaeiiai ieeniaiiy e?i?ae?a, nooiaiai ii?ooaiue nenoaie
i?ioe-?aaeeeaeueiiai caoenoo, ae?aaeai?noth aoi?eiii? ?ioiii?
iaaeinoaoiino? oa ?ioaineai?noth ?ioieneeaoe?eiiai neiae?iio i?e
o?ii?/ieo aeeoocieo caoai?th-aaiiyo ia/?iee a caeaaeiino? a?ae aa??aioo
ee?i?/iiai ia?aa?ao caoai?thaaiiy.

3. Cai?iiiiiaaia eeaneo?eaoe?y aiaeioieneeico ca ?ioaa?aeueieie
e?eoa??yie: oiene/i?noue ieacie e?ia?, ai?no na?aaeiueiiieaeoey?ieo
iaioeae?a oa iaeiiiaiai ae?aeueaeaa?aeo a e?ia?.

4.Anoaiiaeaii u?eueiee aca?iica’ycie i?ae nooiaiai aeenaaeoa??ico oe??e
oa nooiaiai iaaeinoaoiino? O-ee?oeiii? oa oaaioeeoa?ii? eaiie
?ioii?aaeoeaiino?.

5.Aeiaaaeaii ae?aaiinoe/ia oa i?iaiinoe/ia cia/aiiy ?aa?iia?iiai
aeenaaeoa??ico oe??e i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee.

6.Anoaiiaeaii ei?aeyoe?eio aca?iicaeaaei?noue i?ae nooiaiai
i?e?iaeaiaio-iiai aeenaaeaino, ?ioaineai?noth aiaeioieneeico oa nooiaiai
?ioiieo ii?ooaiue i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee.

7.Aeiaaaeaiee iiceoeaiee aieea o?io?eacie?io ia onoiaiiy i?iya?a
neiae?iio aiaeiaaiii? ?ioieneeaoe??, i?aeneeaiiy iiooaeiino?
i?ioe?aaeeeaeueieo nenoai caoenoo, cae?eniaiiy ?ioiiiiaeoethth/eo
aoaeo?a o iai?yieo i?aeneeaiiy i?ioeaaeoa??aeueiiai ?ioi?oaoo.

8.Iaa?oioiaaia aeioe?euei?noue aeeoa?aioe?eiaaiiai i?ecia/aiiy
o?io?eacie?io a caeaaeiino? a?ae nooiaiy aiaeioieneeico i?e o?ii?/ieo
aeeoocieo caoai?thaaiiyo ia/?iee aeey ei?aeoe?? aeuaaeacaieo ii?ooaiue.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a

1.Cai?iiiiiaaiee eiiieaen a?io?i?/ieo, o?i?eiaiae?oe/ieo,
i?e?ia?i-eia?/ieo, ?ioiieia?/ieo oa ?ino?oiaioaeueieo iaoiae?a
aeine?aeaeaiiy aeicaiey? ioe?ieoe nooi?iue ii?ooaiue iniiaieo eaiie
iaoiaaiaco i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee ? iiaea
aeei?enoiaoaaoenue ye a iaoeia?e ?iaio?, oae ? a i?aeoe/i?e iaaeeoeei?.

2.Ai?iaaaeaeaiiy ?acoeueoao?a eiiieaeniiai aeine?aeaeaiiy ia?ea??a
aiaei-oieneeico, ?ioaineaiino? i?ioean?a a?eueii?aaeeeaeueiiai ieeniaiiy
e?i?ae?a, noaio nenoai i?ioe?aaeeeaeueiiai caoenoo, ?ioiiiai noaoono,
iieaciee?a ianiaoeeo?/ii? ?acenoaioiino? i?aai?cio, i?e?ia?ioeaiico
iiaa?oiaaeo oa aeeaieeo oa??a oe??e, ai?noo aeayeeo i?e?iaeaiaio?a a
e?ia? oai?eo a i?aeoeeo ?icoe?eei iiaeeeaino? ae?aaiinoeee oa
i?iaiicoaaiiy ia?aa?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee,
?aiiueiai aeyaeaiiy ?ioiiaeao?oeeoieo noai?a.

3.Aeyaeaiiy iiooaeieo aeac?ioieneeaoe?eieo oa ?ioiiiiaeoethth/eo
aeanoe-ainoae o?io?eacie?io, ii?yae ?c aioeieneaeaioieie oa
oeeoii?ioaeoi?ieie, aeaei iiaeeea?noue aeeth/eoe eiai aei eiiieaenii?
oa?ai?? o?ii?/ieo aeeoocieo caoai?th-aaiue ia/?iee, iaeii/anii ciaioeaoe
e?euee?noue i?ecia/aieo i?aia?ao?a aacenii? oa?ai??.

4.?ic?iaeai? ee?i?ei-eaai?aoi?i? iieacieee ? i?ia?aia
aeeoa?aioe?eiaaiiai i?ecia/aiiy o?io?eacie?io a caeaaeiino? a?ae nooiaiy
aaaeeino? aiaeioieneeico aeaee iiaeeea?noue i?aeaeueoe aoaeoeai?noue
aaceniiai e?eoaaiiy oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee,
ciaioeoe o?eaae?noue ia?aaoaaiiy oai?eo a noaoe?iia??, nei?ioeoe /enei
oneeaaeiaiue.

Ai?iaaaeaeaiiy ?acoeueoao?a aeine?aeaeaiiy a i?aeoeeo

?acoeueoaoe ?iaioe ai?iaaaeaeai? a e?eoaaeueio i?aeoeeo oa?aiaaoe/ieo,
aano?iaioa?ieia?/ieo a?aeae?eaiue i?nueeeo oa iaeanieo e?ea?aiue
i.*a?i?aoe?a, Ee?aa, Iaeane, Eueaiaa, Oa?eiaa, Oa?iiiiey, Oa?niia,
Caii??aeaey, A?iieoe?, Oaeai?iaea, Eoaainueea, Aeiiaoeueea.

Iaoa??aee aeena?oaoe?? aeei?enoiaothoueny o eaeoe?eiiio eo?n? aeey
nooaeaio?a, e?ea??a-?ioa?i?a, i?aeoe/ieo e?ea??a oa i?e i?iaaaeaii?
i?aeoe/ieo caiyoue ia eaoaae?ao oa?ai?? Aoeiaeinueei? aea?aeaaii?
iaaee/ii? aeaaeai??, Iaeanueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo,
Caii??cueeiai aea?aeaaiiai ?inoeoooo oaeineiiaeaiiy e?ea??a,
Eoaainueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, Aeiiaoeueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo, Oa?eianueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo, A?iieoeueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo ?iai? I.?.I??iaiaa, Oa?iii?euenueei? aea?aeaaii? iaaee/ii?
aeaaeai??, ?aaii-O?aie?anueei? aea?aeaaii? iaaee/ii? aeaaeai??,
Oaeai?iaenueeiai aea?aeaaiiai oi?aa?neoaoo, Iaoe?iiaeueiiai iaaee/iiai
oi?aa?neoaoo ?i. I.I.Aiaiiieueoey, Euea?anueeiai aea?aeaaiiai iaaee/iiai
oi?aa?neoaoo, Oa?e?anueeiai ?inoeoooo oaeineiiaeaiiy e?ea??a,
iaaee/iiai ?inoeoooo Oe?a?inueei? anioe?aoe?? ia?iaeii? iaaeeoeeie.

Iniaenoee aianie caeiaoaa/a

Aianie aaoi?a a io?eiaiiy ?acoeueoao?a ? iniiaiei ? iieyaa? o aeai??
oaie, ia’?io oa iaoiae?a aeine?aeaeaiiy, o iinoaiiaoe? iaoe oa
oi?ioethaaii? caaaeaiue aeine?aeaeaiiy. Naiino?eii i?iaaaeaii iniiaiee
ia’?i ee?i?/ieo, ?ino?oiaioaeueieo oa eaai?aoi?ieo aeine?aeaeaiue,
aiae?c oa ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiiy, iaa?oiooaaiiy
iaoiae?a e?eoaaiiy, i?aeaioiaea iaoeiaeo iaoa??ae?a aei ioae?eaoe??.
Iniaenoi noi?ioeueiaai? aeniiaee ?iaioe, ?ic?iaeai? i?aeoe/i?
?aeiiaiaeaoe?? ? caaacia/aii ?o ai?iaaaeaeaiiy a iaaee/io i?aeoeeo oa
a?aeia?aaeaiiy a iioae?eiaaieo i?aoeyo.

Ai?iaaoe?y ?iaioe

Iniiaii iieiaeaiiy aeena?oaoeieiii ?iaioe aeiiia?aeaeenue ia
i?aenoieiaeo iaoeiaeo eiioa?aioe?yo ni?a?ia?oiee?a Aoeiaeinueei?
aea?aeaaii? iaaee/ii? aeaaeai?? (1995-1998 ?.?.), ia Ia?oiio
Iaoe?iiaeueiiio eiia?an? aano?iaioa?ieia?a Oe?a?ie (i.
Aei?i?iiao?ianuee, 19-21 aa?aniy 1995 ?ieo), ia Ia?oiio neiiiceoi? c
i?aeia?iaeiith o/anoth «O??o?a?/i? i?iaeaie oa aeieia?y» (i.*a?i?aoe?,
5-6 aeiaoiy 1995 ?ieo), ia Oaeuee-neiiiceoi? ?92 «Iiaua iai?aaeaiey a
aaiaoieiaee» (Naieo-Iaoa?ao?a, 21-22 /a?aiy 1996 ?.), ia neiiiceoi?
«Aeooaeuei? ieoaiiy ?aaa?e?oaoe?? aano?iaioa?ieia?/ieo oai?eo»
(i.*a?i?aoe?, 17-18 ea?oiy 1996 ?ieo), Ieaioi? I?aae?iiy Oe?a?inueeiai
oiaa?enoaa aa?iioieia?a oa aa??ao??a «O?c?ieia?y ? iaoieia?y i?aai?a
o?aaeaiiy o in?a iioeeiai ? noa?a/iai a?eo» (18-20 aa?aniy 1996 ?ieo),
ia Ae?oaiio ?in?enueeiio Aano?iaioa?ieia?/iiio oeaei? (i.Iineaa, 7-13
a?oaeiy 1996 ?ieo), ia Ae?oaiio Oe?a?inueeiio oeaei? aano?iaioa?ieia?a
(i. Aei?i?iiao?ianuee, 23-25 aa?aniy 1997 ?ieo), ia O?aoueiio
?in?enueeiio Aano?iaioa?ieia?/iiio oeaei? (i.Iineaa, 15-21 eenoiiaaea
1997 ?ieo), Ia?o?e iaoeiai-i?aeoe/i?e eiioa?aioe?? ii/aoeoth/eo
iaoeiaoe?a oa iieiaeeo a/aieo Aoeiaeie «A?ieia?y, iaaeeoeeia, aeieia?y»
(i.*a?i?aoe?, 23-24 ethoiai, 18-19 aa?aciy 1996 ?ieo), iaoeiai —
i?aeoe/i?e eiioa?aioe?? «Aeooaeuei? i?iaeaie iaaee/iiai ianeoaiaoaaiiy
i?aoethth/eo ia cae?cie/iiio o?ainii?o?. Aeieia?y oa noai caei?ia’y
ianaeaiiy a no/anieo oiiaao. Eaco?noeea, aia?aoi? oa ?ino?oiaioaeuei?
iaoiaee aeine?aeaeaiiy, ae?aaiinoeea oa e?eoaaiiy caoai?thaaiue
ethaeeie» (i.Oaeai?iae, 12-14 /a?aiy 1996 ?ieo), I?aeia?iaeiiio
Oe?a?ii-Oaaaenueeiio neiiiceoi? «Aeooaeuei? ieoaiiy iaaee/ii? aeiiiiiae
ianaeaiith» (i.*a?i?aoe? — Engelholm, 17-18 aa?aniy 1996 ?ieo),
I?aeia?iaei?e eiioa?aioe?? «Yeieiae/aneea aniaeou caa?yciaiey
ie?oaeathuae n?aaeu» (i.Ee?a, 21-25 ea?oiy 1996 ?ieo), XIV c’?cae?
oa?aiaao?a Oe?a?ie (i.Ee?a, 21-25 aeiaoiy 1998 ?ieo), *aoaa?oiio
?in?enueeiio Aano?i-aioa?ieia?/iiio oeaei? (i.Iineaa, 16-20 eenoiiaaea
1998 ?ieo).

Ai?iaaoe?y aeena?oaoe?? aoea i?iaaaeaia ia ni?eueiiio can?aeaii?
oa?aiaaoe/ieo eaoaae?, iaoeiai? eii?n?? Aoeiaeinueei? aea?aeaaii?
iaaee/ii? aeaaeai??, *a?i?aaoeueei? iaeanii? i?aai?caoe?? «Anioe?aoe?y
oa?aiaao?a ?i. aeaae. A.O. Aaneeaiea» 9 a?oaeiy 1998 ?ieo.

Ioaeieaoei?

Ca oaiith aeena?oaoei? iioaeieiaaii 15 iaoeiaeo i?aoeue (a o. /. 6
noaoae), io?e-iaii iina?ae/aiiy ia ?aoeiiiaeicaoi?nueeo i?iiiceoeith
(?35/97 a?ae 10.12.1997 ?. AAeIA «Iaoiaeeea aecia/aiiy nooiaiy
?ioiiaeao?oeeoo»), aeaeaii iaoiaee/i? ?aeiiaiaeaoei?.

No?oeoo?a oa ianya aeena?oaoe??

Aeena?oaoe?y neeaaea?oueny c? anooio, iaeyaeo e?oa?aoo?e, iieno iaoiae?a
aeine?aeaeaiiy, ee?i?/ii? oa?aeoa?enoeee oai?eo, ?acoeueoao?a aeanieo
aeine?aeaeaiue, aeeeaaeaieo o i’yoe ?icae?eao, iaaiai?aiiy ?acoeueoao?a,
aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e, nieneo aeei?enoaieo aeaea?ae.

Aeena?oaoe?y aeeeaaeaia ia 210 noi??ieao iaoeiiieno, ?ethno?iaaia 35
oaaeeoeyie oa 23 ?enoieaie. Iieaae/ee e?oa?aoo?e i?noeoue 440 aeaea?ae a
o./. 151 eaoeieoeath.

INIIAIEE CI?NO ?IAIOEINIIAIEE CI?NO ?IAIOE

Iaoa??ae oa iaoiaee aeineiaeaeaiiy

C 1995 ii 1998 ?iee i?iaaaeai? aeine?aeaeaiiy o 140 oai?eo ia o?ii?/i?
aeeooc-i? caoai?thaaiiy ia/?iee (/ieia?e?a — 92, ae?iie — 48) oa 30
i?aeoe/ii caei?iaeo in?a (/ieia?e — 17, ae?iie — 13), a?eii a?ae 22 aei
60 ?ie?a. 42 (30,0%) oai?eo no?aaeaea-ee ia o?ii?/iee aaiaoeo ?c
iecueeith aeoeai?noth (OAIA), 55 (39,3%) oai?eo — ia o?ii?/iee aaiaoeo c
iii??iith aeoeai?noth (OAIA), 43 (30,7%) oai?eo — ia oee?ic ia/?iee
(OeI). Ia?aaaaeath/eie ao?ieia?/ieie oaeoi?aie o ianoaaeaieo oai?eo aoee
a??one aaiaoeoo A o oac? ?ioaa?aoe?? ? N, ii?yae ?c oiene/ieie, a oiio
/ene? aeeiaieueieie, aieeaaie. O?eaae?noue caoai?thaaiiy noaiiaeea a?ae
1 aei 16 ?ie?a. O?ii?/iee aaiaoeo oa oee?ic ia/?iee ae?aaiinooaaeeny ca
caaaeueiii?eeiyoeie ee?i?/ieie, eaai?aoi?ieie e?eoa??yie, a oaeiae
?acoeueoaoaie ?ino?oiaioaeueieo oa ii?oieia?/ieo aeine?aeaeaiue o
a?aeiia?aeiino? c eeaneo?eaoe??th I?aeia?iaeii? ?iai/i? a?oie
Anana?oiueiai eiia?ano aano?iaioa?ieia?a (Ein-Aiaeaeaean, 1994),
caoaa?aeaeaii? XIV c’?caeii oa?aiaao?a Oe?a?ie.

Ianoaaeaiiy, e?eoaaiiy ? aeeiai?/ia niinoa?aaeaiiy ca oai?eie
cae?enithaaeinue a oiiaao I, II oa?aiaaoe/ieo oa aano?iaioa?ieia?/iiai
a?aeae?eaiue i?nueei? ee?i?/ii? e?ea?i? ? 1 i?noa *a?i?aoe?a.

Oai?ei ia o?ii?/iee aaiaoeo oa oee?ic ia/?iee i?iaiaeeee
caaaeueiiee?i?/i? ianoaaeaiiy: iieooaaiiy, o?ce/ia ianoaaeaiiy, eiiieaen
ee?i?/ieo, a?io?i?/ieo, ?ino?oiaioaeueieo, i?e?ia?ieia?/ieo,
?iyiieia?/ieo, ?aioaaiieia?/ieo, iaoi-ii?oieia?/ieo iaoiae?a
aeine?aeaeaiiy. Oeueo?acaoeiaa aeine?aeaeaiiy i?aai?a /a?aaii?
ii?iaeieie i?iaiaeeeeny ca aeiiiiiaith aia?ao?a o??i «Aloka» oa
«Siemens». Aiaeineii?y no?aaioiaeo, oeoiea, aeaaiaaeoeyoeiaei? eeoee
i?iaiaeeeanue ca aeiiiiiaith o?a?iaano?ineiia o??ie «Olimpus» (ssiii?y).
E?ia o oai?eo a?aee c e?eoueiai? aaie a?aioe? iaoua, i?ney 12-15
aiaeeiiiai aieiaeoaaiiy.

Aecia/aiiy ia?ea??a a??on?a aaiaoeoo oa oace ?o ?ai?iaeoeoeaii?
aeoeaiino? a ne?iaaooe? e?ia? i?iaiaeeee ca aeiiiiiaith ?aaeoe?e
?ioiioa?iaioiiai aiae?co, aeei?enoiaoth/e oano-nenoaie o??ie «?cioii»
(Oe?a?ia).

?ioeec?eio i?eoe?eueio a?iin?th ia/?iee aeeiioaaee ca aeiiiiiaith aieee
Silver liver bioply neadle i?ae /an eaia?ineii?? /e /a?acoe??ii.
Iaoa??ae o 10% ?ic/ei? oi?iaeueaeaa?aeo iaaeoiaeea aei iaoia?noieia?/ii?
eaai?aoi???, aea i?iaiaeeeinue ii?oieia?/ia aeine?aeaeaiiy ca
caaaeueiii?eeiyoith iaoiaeeeith i?ney oa?aoaaiiy aaiaoienee?iii ?
aiceiii.

Ai?no a e?ia? a?aeiiaeaiiai aeooao?iio (AA) aecia/aee oeo?aoe?eiei
iaoiaeii I.A. O?aa?ii? (1955) o iiaeeo?eaoe?? ?.O. Iaueoaia, ?.A.
Iao?iai? (1983), iaeiiiaiai ae?aeueaeaa?aeo (IAeA), aac ?i?oe?aoe??, c
?i?oe?aoe??th anei?aaoii, IAAeOI2 — ca TH.A. Aeaae?i??iaei, I.?.
A?/aeiaei (1972), iieaeoey?ieo i?iaeoeo?a ia?ieneaeiiai ieeniaiiy
e?i?ae?a (?cieueiaaieo iiaea?eieo ca`yce?a (?IC), ae??iiaeo eii’thaao?a
(AeE), eaoiae??i?a oa ni?yaeaieo o???i?a (ENO) — ca ?.A. Aie/aai?nueeei
?c ni?aaao. (1989). Aeoeai?noue oa?iaio?a aea/aee: aeooao?iiia?ieneaeace
(AI) oa aeooao?ii?aaeoeoace (A?) — ca ?.O. Iaueoaiei (1982), aeooao?ii —
S — o?ainoa-?a-ce (AO) — ca ?.O. Iaueoaiei (1987),
aetheici-6-oinoaoaeaa?ae?iaaiace (A-6-OAeA) ca A. Kornberg. B.L.
Horecker (1955) a iiaeeo?eaoe?? TH.E. Caoa?’?ia (1967), i?aeue,
oeeie-noia?ieneaeaeeniooace (NIAe) — ca R. Fried (1975). Aeoeai?noue
oa?iaio?a ?ic?aoiaoaaee ia 1a aaiiaeia?io (Ib), ai?no yeiai aea/aee
oeeai?aeiei iaoiaeii.

Caaaeueio e?euee?noue O-e?ioioeeo?a o ia?eoa?e/i?e e?ia? aecia/aee
iaoiaeii niiioaiiiai A-?icaoeiooai?aiiy (A-?OE) ca Jondal e.a. (1972) o
iiaeeo?eaoe?? A.?.*a?aae??aa (1989), e?euee?noue oaio?e?icaeaaeieo
?icaoeiooai?thth/eo ee?oei (oaio?e?i/ooeeaeo (OO*) ?
oaio?e?i?acenoaioieo (OO?)) aecia/aee ca iaoiaeii Limatibul S. e.a.
(1978) c ia/eneaiiyi eiao?oe??ioo OO?/OO* (???). OO?-?OE o?aeooaaeenue
ye noaiiioeyoe?y c ia?aaaaeii O-oaeia?iith aeoeai?noth, OO*-?OE, ye
noaiiioeyoe?y, caaaa/aia O-noi?ani?aie. Ai?no A-e?ioioeeo?a a
ia?eoa?e/i?e e?ia? aecia/aee iaoiaeii eiiieaiaioa?iiai ?icaoeiooai?aiiy
(AAN-?OE) ca A.?.*a?aae??aei (1976), e?euee?noue «aeoeaieo»
?icaoeiooai?thth/eo ee?oei (A-A-?OE) — ca iaoiaeii Smith e.a. (1975).
Oaaioeeoa?io aeoeai?noue (OA) iaeo?io?e?a ? oaaioeeoa?ia /enei (O*)
aecia/aee ca iiaeeiaiiyi iaeo?io?eueieie eaeeioeeoaie noao?eieieo ?209
ca E.O. *a?iooaiei, E.N. Eiainiaith (1978). ??aaiue ?ioaeiaoe?i?a
iniiaieo eean?a M,G,A a ne?iaaooe? e?ia? aecia/aee iaoiaeii ?aae?aeueii?
?ioiiaeeooc?? ca G. Mancini e.a.(1965), eiioeaio?aoe?th oee?eoethth/eo
?ioiieo eiiieaen?a (Oe?E) iaoiaeii i?aoeei?oaoe?? o 5% ?ic/ei?
iie?aoeeaiae?eieth ca Digeon, Laver (1977).

Noai aooioei?e oe??e aea/aee iaoiaeii aaeoa??aeueieo a?aeoene?a ca
I.I.Eeaiia?nueeith (1966). Aeey aeae?eaiiy aaeoa??e aeei?enoiaoaaee
naeaeoeai? na?aaeiaeua ? iaoiaee, iienai? a ea??aieoeoa? B. Mirelis
(1972).

??aaiue oiene/iino? ieacie e?ia? (OI), ??aaiue oiene/iino? na/? (ON ) oa
ee?-?ain aiaeiaaiieo oienei?a (No) aecia/aee ca aeiiiiiaith
ia?aiaoe?eiiai oanoo ca A.N. Aaianii (1958) o iiaeeo?eaoe?? A.I.
Eiiia/oea (1992). Ai?no a ne?iaaooe? e?ia? na?aaeiueiiieaeoey?ieo
iaioeae?a (NII) aecia/aee iaoiaeii I.?. Aaa??aeyia (1983). Ai?no a e?ia?
i?e?iaeaiaio?a: cae?ca, i?ae?, oeeieo, ia?aaioeth, i?eaeth, eiaaeueoo,
naeioeth, eaaei?th — aecia/aee ca aeiiiiiaith aoiiii-aaeni?aoe?eiiai
aiae?co.

On? oai?? ca aeiaaeeiaith iciaeith aoee ?iciiae?eai? a caeaaeiino? a?ae
i?iaaaeaii? oa?ai?? ia aea? a?oie: 1) oai?? ia?oi? a?oie (n = 54)
io?eioaaee o?aaeeoe?eio aacenio oa?ai?th c anaioe?aea-oi?oa a yeino?
aaiaoii?ioaeoi?a ? neoaeeee eiio?ieai aoaeoeaiino? e?eoaaiiy; 2) oai??
ae?oai? a?oie (n = 86) a eiiieaen? e?eoaaeueieo cania?a iaea?aeoaaee
2,5% ?ic/ei o?io?eacie?io ii 2 ie c ??ciei ?aaeeiii oa oeyoii aaaaeaiiy
i?ioyaii 10 aei?a ?c iaeii/aniei aeeo/aiiyi i?aia?ao?a
aaiaoii?ioaeoi?ii? oa aioeieneaeaioii? ae??.

Noaoenoe/io ia?iaeo ?acoeueoao?a aeine?aeaeaiiy cae?enithaaee ca
niaoe?aeueieie i?ia?aiaie ca aeiiiiiaith e?eoa??th a??ia?aeiino?
??cieoe? No’thaeaioa, iaia?aiao?e/ieo iaoiae?a ia/eneaiiy: ca e?eoa???i
Eieiiai?iaa-Ni??iiaa, eiao?oe??ioa ei?aeyoe?? ?aia?a Ni??iaia.
Aeei?enoiaoaaee oaeiae ei?aeyoe?eiee aiae?c ?c ?ic?aooieii eiao?oe??ioa
ei?aeyoe?? oa eiai a??ia?aeiino? ca iaoiaeii «Z» O?oa?a. I?e oeueiio
aeei?enoiaoaaee PC IBM 586DX4-100, ca aeiiiiiaith i?ia?ai «Microsoft
Excel-97» ? «Statgraphics».

INIIAI? ?ACOEUeOAOE AeINE?AeAEAIIssINIIAI? ?ACOEUeOAOE AeINE?AeAEAIIss

Anoaiiaeaii, ui caaino?aiiy o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee
noi?iaiaeaeo?oueny i?aeneeaiiyi ?ioaineaiino? aiaeioieneeico, yeee
aeinyaa? iaeaeuiai nooiaiy aaaeeino? i?e OeI. Aeieacii oeueiai ?
aeinoia??ia i?aeaeuaiiy OI oa ON, ye? ? ?ioaa?aeueieie iieacieeaie
noeoiiiai oiene/iiai aoaeoo o oai?eo ia OAeCI an?o ee?i?/ieo a?oi
niinoa?aaeaiiy o ii??aiyii? c a?oiith i?aeoe/ii caei?iaeo in?a (ICI)
(p<0,05) ?c iaeneiaeueieie cia/aiiyie iieaciee?a a a?oi? oai?eo ia OeI. Cia/ia ca?eueoaiiy OI oa ON i?e OeI iaoiiaeaii ca?eueoaiiyi ieoiii? aaae neiae?iio ii?oieaaaeueiiai ooiooaaiiy ?c ?icaeoeii nenoaiii? aiaeioienai??, ia?inoath/ith ia/?ieiaiee?oeiiith iaaeinoaoi?noth, a oaeiae aeinoia??iei cieaeaiiyi ee??aino aiaeiaaiieo oienei?a o oe??? a?oi? oai?eo (p<0,05). Nooi?iue aaaeeino? aiaeioieneeico o oai?eo ia OAeCI c?inoa? o i?yi?e aca?ii-caeaaeiino? ?c ??aiai caaaeueii? a?e??oa?iai?? (r = 0,641; p<0,001); aeoeai?noth oa?iaio?a: aeai?iai?iio?ainoa?ace (r = 0,421; p<0,05); eoaeii? oinoaoace (r = 0,472; p<0,02); iieacieeii oeiieiai? i?iae (r = 0,562; p<0,01); ai?noii g- aeiaoe?i?a a e?ia? (r = 0,634; p<0,001) oa o cai?ioi?e aca?iicaeaaeiino? ?c ai?noii aeueaoi?i?a a e?ia? (r = -0,752, ?<0,001). Eieeaaiiy nooiaiy u?eueiino? ei?aeyoe?eiiai ca'yceo i?ae neaaeei ? na?aaeiuei? neee ia aeathoue iiaeeeaino? aeei?enoaoe iieacieee oeeoie?oe/iiai, oieanoaoe/iiai oa ?ioiicaiaeueiiai neiae?ii?a o yeino? ia?ea??a aiaeioieneeico. Iaeiie/aiiy a e?ia? i?iaeoeo?a eaoaaie?cio aiaeiaaiieo a?ee?a, aiaeioienei?a, aeia/ieo eeneio oa ?ioeo oiene/ieo iaoaaie?o?a, ye? iaeaaeaoue aei iieaeoe na?aaeiuei? iane ? aieiae?thoue nenoaiiith oiene/iith ae??th ia i?aai?ci, ni?ey? i?ia?anoaaiith neiae?iio aiaeiaaiii? ?ioieneeaoe?? o oai?eo ia OAeCI. Anoaiiaeaiee i?yiee ei?aeyoe?eiee ca'ycie aeniei? u?eueiino? i?ae OI oa ai?noii NII o ne?iaaooe? e?ia? (r = 0,843; p<0,001) aeicaieea aeei?enoaoe oe? ?ioaa?aeuei? iieacieee o oi?ioaaii? eeaneo?eaoe?? aiaeioieneeico ca nooiaiyie aaaeeino?: ? nooi?iue (eaaeee) ia?aaeaa/a?: OI - 110 - 149 o.i./ie, NII - 0,288 - 0,315 o.i.; ?? nooi?iue (na?aaeiuei? aaaeeino?): OI - 150 - 174 o.i./ie, NII - 0,316 - 0,368 o.i.; ??? nooi?iue (aaaeeee): OI - 175 - 200 o.i./ie, NII - 0,369 - 0,412 o.i.; IV nooi?iue (ae?ae aaaeeee): OI - a?eueoa 200 o.i./ie, NII - a?eueoa 0,412 o.i. C o?aooaaiiyi cai?iiiiiaaii? eeaneo?eaoe?? a a?oi? oai?eo ia OAIA anoaiiaeaii iaeaeuee a?aenioie iaoe??io?a c eaaeei nooiaiai aaaeeino? aiaeioieneeico (54, 1%), iaeieae/ee a?aenioie ?c aaaeeei nooiaiai (13,5%) oa ia aeyaeaii iaoe??io?a ?c ae?ae aaaeeei nooiaiai aiaeiaaiii? ?ioieneeaoe??. A a?oi? oai?eo ia OAIA ia?aaaaeath/ee a?aenioie neeaaeathoue iaoe??ioe ?c na?aaei?i oa aaaeeei nooiaiyie aaaeeino? aiaeioieneeico (34,0% oa 30,0% a?aeiia?aeii). Na?aae oai?eo ia OeI ca?a?no?iaaii 57,2% iaoe??io?a ?c ae?ae aaaeeei nooiaiai aiaeioieneeico, a oie /an ye oai?? ?c aaaeeei nooiaiai neeaaeathoue 48%. Naia eiioeiaaio iaoe??io?a ?c ca?a?no?iaaiei IV nooiaiai aiaeiaaiii? ?ioieneeaoe?? ca ee?i?/ieie iciaeaie, eaai?aoi?ieie oa ?ino?oiaioaeueieie iieacieeaie iaeaaeeoue aei eaoaai??? oai?eo ia OAeCI, oneeaaeiaieo ii?oinenoaiiith ia/?ieiaith aioeaoaeiiao??th. Iiooaeiei aeaea?aeii aiaeioieneeico i?e OAeCI ? aeoeaaoe?y i?ioean?a A?IE, a?eueo cia/ia a a?oiao oai?eo ?c anoaiiaeaiei aaaeeei oa ae?ae aaaeeei nooiaiai aiaeioieneeico. Oae, ??aaiue i?ii?aeieo (?IC, AeE, ENO) oa e?ioeaaeo (IAeA) i?iaeoeo?a A?IE o yeeo anoaiiaeaii aenieee ??aaiue nenoaiieo oiene/ieo aoaeo?a c?inoa? o i?yi?e caeaaeiino? ?c OI e?ia? (p<0,05). Iayai?noue i?yiiai ei?aeyoe?eiiai ca'yceo aeniei? u?eueiino? i?ae iieacieeii OI e?ia? oa ai?noii IAeA a e?ia? (r=0,881, p<0,001) aeicaieeea aaanoe o?ao?e ae?aaiinoe/iee e?eoa??e a eeaneo?eaoe?th aiaeioieneeico: ? nooi?iue aaaeeino? ia?aaeaa/a? ai?no IAeA a e?ia? a ae?aiacii? 4,0-5,7 iiieue/e, ?? nooi?iue - 5,8-7,3 iiieue/e, ??? nooi?iue - 7,4-8,5 iiieue/e, IV nooi?iue - a?eueoa 8,5 iiieue/e. Ia oii? cia/ii? aeoeaaoe?? i?ioean?a A?IE, c?inoaiiy nooiaiy aaaeeino? aiaeiaaiii? ?ioieneeaoe?? o oai?eo ia OAeCI aeyaeaii ?icaaeainiaai?noue o ooieoe?iioaaii? oaeoi??a i?ioe?aaeeeaeueiiai caoenoo. I?ia?anoth/a aeinoia??ia ciaioaiiy ai?noo AA a e?ia? oai?eo ia OAeCI ii i??? ia?inoaiiy aaaeeino? aiaeioieneeico iaoiiaeaii eiai aaaeeeaith ?ieeth o ooieoe?iioaaii? nenoaie i?ioe?aaeeeaeueiiai caoenoo oa i?e?iaeiuei? nenoaie aeaoieneeaoe??. Iaea?eueo cia/iei aoei ciaioaiiy ai?noo a e?ia? AA o oai?eo ?c ae?ae aaaeeei nooiaiai aiaeioieneeico (0,43 ±0,24 iiieue/e), ui iia'ycaii ?c c?inoaiiyi iio?aae a iueiio aeey eii'thaaoe?? ?c enaiia?ioeeaie oa aiaeiaaiieie iaoaaie?oaie o ae?oa?e oac? aeaoieneeaoe??. Aeieacii oeueiai ? eiiiainaoi?ia i?aeaeuaiiy aeoeaiino? AO ii i??? c?inoaiiy aaaeeino? aiaeioieneeico. Ca oiia i?aeneeaiiy i?ioean?a e?iiia?ieneaeaoe?? o oai?eo ia OAeCI c?inoa? niiaeeaaiiy AA aeey iaeo?ae?caoe?? ia?ieneaeo aiaeith, e?iiia?ieneaeieo ?aaeeeae?a. I?i oea na?ae/eoue c?inoaiiy aeoeaiino? AI ii i??? i?aeaeuaiiy OI e?ia? (p<0,05). ?ioith i?e/eiith ciaioaiiy ai?noo AA iiaea aooe aeao?oeeo oiiaeo a?aeiiaeaieo aea?aaeaio?a i??eaeeiaeeioeeaioeae?a. Iai?yiei na?ae/aiiyi oeueiai ? c?inoaiiy ai?noo IAeA c ?i?oe?aoe??th IAAeOI2 ii i??? ca?eueoaiiy OI e?ia? (p<0,05) oa aeinoia??ia cieaeaiiy aeoeaiino? A-6-OAeA ?c i?i?iaeueieie cia/aiiyie a a?oi? oai?eo ?c IV nooiaiai aiaeioieneeico (2,28 ± 0,032 iiieue IAAeOI2 ca 1 oa. ia 1a Hb; o caei?iaeo - 3,0 ± 0,081 iiieue IAAeOI2 ca 1 oa. ia 1a Hb). Ciaioaiiy ai?noo AA iiaea aooe ni?e/eiaia aaeueioaaiiyi eiai a?ineioaco a aaia-aeooai?eueiiio oeeee? Iaeno?a aiane?aeie cieaeaiiy aeoeaiino? a?aeiia?aeieo neioaoac, aeao?oeeoo AOO, iecueeiai ai?noo oeenoa?io a aaiaoioeeoao, iineeaiiai ieeniaiiy inoaiiueiai aei aeenoeueo?aeii? oi?ie (A.Meister, 1983). C?inoaiiy aeoeaiino? A? ii i??? ia?inoaiiy nooiaiy aaaeeino? aiaeioieneeico (p<0,05) ?, aacoiiaii, eiiiainaoi?ii-i?enoinoaaeueiei iaoai?ciii. I?ioa aiii ? iaei aoaeoeaiei /a?ac a?aenooi?noue iaiao?aeii? e?eueeino? a?aeiiaeaieo aea?aaeaio?a. I?eai?/aiiy aeoeaiino? NIAe o oai?eo ia OAeCI ii i??? ia?inoaiiy ?ioai-neaiino? aiaeioieneeico iaoiiaeaii noiooi?i aeao?oeeoii oeeieo, iacai?ioi?i a?aeiiaeaiiyi i?ae? o aeoeaiiio oeaio?? oa?iaioa oa ieeniaiiyi ooieoe?iiaeueieo o?ieiaeo a?oi. Oaeiae, aeineoue eiia??ii, ui oiene/i? i?iaeoeoe i?ioaie?co aeeeeeathoue eiioi?iaoe?ei? ci?ie iieaeoe oa?iaio?a, ui i?ecaiaeeoue aei ao?aoe ieie nai?o ooieoe?iiaeueieo aeanoeainoae. Aeieacii oeueiai i?eiouaiiy ? iaeneiaeueia i?eai?/aiiy aeoeaiino? NIAe a a?oi? oai?eo ia OAeCI ?c ae?ae aaaeeei nooiaiai aaaeeino? aiaeioieneeico (2,24 ± 0,034 ieiieue IAAeOI2 ca 1 oa ia 1a Hb; o caei?iaeo - 3,5 ± 0,102 ieiieue IAAeOI2 ca 1 oa ia 1 a Hb). Oea iiaea aooe ni?e/eiaia oaeiae cieaeaiith aeoeai?noth A-6-OAeA, a?eueo cia/iith ?ioaineai?noth i?ioean?a A?IE a oe?e a?oi? oai?eo oa ?ai?aai?caoe??th ee?oeiieo iaia?ai, ine?eueee oea iiooaeiee iaia?aiaca'ycaiee oa?iaio. Oe?eaaei c oi/ee ci?o ioe?iee nooiaiy aaaeeino? aiaeiaaiii? ?ioieneeaoe?? aey-aeeiny ni?aa?aeiioaiiy i?iieneaeaioii? oa aioeieneaeaioii? aeoeaiino?. A eiio-?ieuei?e a?oi? a?aeiioaiiy ai?noo IAeA aei aeoeaiino? NIAe neeaaeaei 1,1. A oie /an, ye a a?oi? oai?eo c ? nooiaiai aiaeioieneeico oeae iieacieo c?inoaa aei 2,0; ?? nooiaiai - 2,8; ??? - 3,2; IV - 3,8. I?ia?an?y iieacieea na?ae/eoue i?i cia/ia i?eai?/aiiy nenoaie i?ioe?aaeeeaeueiiai caoenoo ?c nooiaiai ia?inoaiiy aiaeioieneeico. Nenoaie i?e?iaeii? aeaoieneeaoe?? oa aioeieneaeaioiiai caoenoo yaeythoue niaith ?aeeio aia?aicaeaaeio, neio?iiii ooieoe?iioth/o nenoaio ca'yceo ?c a?io?i?/ieie no?oeoo?aie, aaia?oth/eie a?aeiiaeai? aea?aaeaioe IAAeOI2 oa IAAeI2, ye?, a naith /a?ao, ? aeaea?aeii aaaio?a eii'thaaoe??, aiaeiaaiieo aioeieneaeaio?a. Iaae?ei?noue nenoaie aecia/a?oueny aeoaethaaiiyi iaoai?ci?a oa?iaioaoeaii? a?io?ainoi?iaoe?? oa ?aaeoe?e eii'thaaoe??, ye?, a iniiaiiio, caaacia/othoueny aieiaiei i?aaiii aeaoieneeaoe?? - ia/?ieith. Ii?ooaiiy aeeiai?/ii? ??aiiaaae a a?e i?aeneeaiiy e?iiia?ieneaeieo i?ioean?a ia oii? iaaeinoaoiino? nenoai i?ioe?aaeeeaeueiiai caoenoo, c?inoath/a ?ioai-neai?noue aiaeioieneeico eiia??ii aieeaathoue ia ooieoe?iiaeueiee noai oaeoi??a nenoaiiiai ?ioi?oaoo. Iaeaaaeeea?o? aeanoeaino? e?ioioeeo?a, oae?, ye ?aoeaioe?y ? o?aini?n?y aioeaaiieo neaiae?a, ni?yiiaai?noue, aeeoa?aioe?aoe?y ?ioiiiai iaaeyaeo oa ?io? ooieoe?? ?ioiiiai iaaeyaeo ca aaiaoe/iith noae?noth aioo??oiueiai na?aaeiaeua i?aai?cio, ciaoiaeyoueny o o?niiio ca'yceo ?c noaiii e?i?aeiiai a?oa?o ?o oeeoiieaciaoe/ii? iaia?aie. O oai?eo ia OAeCI ia oii? aeinoia??iiai i?aeae-uaiiy OI e?ia? oa i?aeneeaiiy ?ioaineaiino? i?ioean?a IIE, ca?a?no?iaaii cia/iee ?ioiiee aeenaaeain. Caaaeueia aaniethoia e?ioiiai?y o oai?eo ia OAeCI an?o ee?i?/ieo a?oi niinoa?aaeaiiy aeieeea ca ?aooiie ciaioaiiy iiioeyoe?? O-e?ioioeeo?a. I?e/iio ?ioaineai?noue O-e?ioiiai?? c?inoaea o i?yi?e aca?ii-caeaaeiino? ?c ae?aaeai?noth oeeoie?oe/iiai i?ioeano a ia/?ioe? oa nooiaiai aaaeeino? aiaeioieneeico (p<0,05), ui iaoiiaeaii ciaioaiiyi ioeo oee?eoethth/eo O-e?ioioeeo?a aiane?aeie ?ioiicaiaeueii? ?io?eueo?aoe?? ia/?ieiai? ia?aio?ie, iaeiie/aiiyi a e?ia? aiaeioienei?a, a?e??oa?io, aeia/ieo eeneio, oiene/ieo i?iaeoeo?a IIE, eiia??ii? iicaia/?ieiai? ?ai?iaeoeoe?? a??ona a e?ioioeeoao, a?ia?i?iaeoeoe?? e?ioioeeo?ia?aoth/eo oaeoi??a, ye?, aieeaath/e ia iaia?aie O-e?ioioeeo?a, cieaeothoue ?o ooieoe?iiaeueio aeoeai?noue oa ciaioothoue o?eaae?noue ?o aeeooy. Cia/ia i?ia?anoth/a cieaeaiiy a?aeiiniiai ai?noo O- noi?ani??a, ii?yae ?c iii??iei ciaioaiiyi O-oaeia??a o oai?eo ia OAeCI a?aeaoaa?oueny o cai?ioi?e i?iii?oe?ei?e caeaaeiino? ?c OI e?ia? oa aeoeai?noth ia?ea??a oeeoie?co aaiaoioeeo?a. Ca?eueoaiiy ??? ii i??? ia?inoaiiy nooiaiy aaaeeino? aiaeioieneeico na?ae/eoue i?i iani?iiiaei?noue noi?ani?ii? eaiee O-ee?oeiiiai ?ioi?oaoo cae?enithaaoe iaaeyae ca aeoeai?noth A-ee?oeiii? iiioeyoe??, ui i?e iayaiino? iiooaeiiai aeaea?aea nainea?e?caoe??, ni?ey? ?icaeoeo aooi?ioiiiai eiiiiiaioo caiaeaiiy. O oai?eo ia OAeCI anoaiiaeaii a??ia?aeia ca?eueoaiiy a?aeiinii? e?eueeino? A-e?ioioeeo?a, i?aeaeuaiiy ?o ooieoe?iiaeueii? aeoeaiino?, i?i ui na?ae/eoue a?ia??ioii-aeiaoe?iai?y M, G, A oa cia/ia ca?eueoaiiy ai?noo Oe?E o ne?iaaooe? e?ia? oai?eo. I?e o?ii?/iiio aaiaoeo? anoaiiaeaii iayai?noue i?yiiai ei?aeyoe?eiiai ca'yceo i?ae a?aeiiniith e?euee?noth A-e?ioioeeo?a a ia?eoa?e/i?e e?ia? oa ?ioaineai?noth i?iya?a oeeoie?oe/iiai neiae?iio, oae ye naia ?ioii? iaoai?cie ? i?ia?aeieie i?e aeai?e iaoieia??. Aiaeii/an, iaie ia i?ine?aeeiao?oueny noaoenoe/ii aeinoia??iee ei?aeyoe?eiee ca'ycie i?ae iieacieeaie ?ioaineaiino? oeeoie?co, oieanoaco, IIE c ia?aiao?aie aoii?aeueiiai ?ioi?oaoo a a?oi? oai?eo ia OeI. Oea iaoiiaeaii oei, ui o ?icaeoeo oee?ioe/ieo ci?i a ia/?ioe? ?ieue ?ioiieo ?aaeoe?e ia?aioiiaoiciiai caiaeaiiy a?aenooia? ia ae?oaee ieai, iaaeath/e i?noea ii?oaeuei?e a?ia?oaic??, ii?oieaaaeueiiio ooiooaaiith, nenoaii?e aiaeioienai?? oa ia/?ieia?e iaaeinoaoiino?. Ia niinoa?iaaeinue oaeiae aeinoia??ii? ??cieoe? i?ae ?ioiieie iieacieeaie o oai?eo ia OAeCI ??cii? ao?ieia??. I/aaeaeii, ui aeaiee oaeo aeaco? ia iayai?noue oi?o?eiaaieo iaoiaaiaoe/ieo iaoai?ci?a ?icaeoeo OAeCI. Ai?no Oe?E a e?ia? oai?eo ia OAeCI c?inoa? i?yii i?iii?oe?eii nooiaith aeoeaiino? oeeoie?oe/iiai i?ioeano a ia/?ioe?, nooiaith aaaeeino? aiaeioieneeico, ui ? ia?ea?ii iayaiino? aooi?ioiiiai eiiiiiaioo oa nooiaiy ooieoe?iiaeueii? iaaeinoaoiino? iae?ioaaaeueii-oaaioeeoa?ii? nenoaie. Cieaeaiiy oaaioeeoa?ii? aeoeaiino? iaeo?io?e?a ii i??? ia?inoaiiy aiaei-oienai?? aeaco? ia o?niee ca'ycie ooieoe?iiaeueieo ?aca?a?a nenoaie IssE ?c aaaee?noth ia/?ieiai-ee?oeiii? iaaeinoaoiino? oa nooiaiai aaaeeino? aiaeioieneeico. ?iaa?n?y a?aeiia?ae? nenoaie IssE ia noeioeyoe?th aaeoa??aeueiei aiaeioieneiii noao?eieiea o oai?eo ia OAeCI coiiaeth? iacaoeuai?noue i?aai?cio ia?aae ?ioaeoe??th oa c?inoaiiy ?eceeo ?icaeoeo ?ioaeoe?eieo oneeaaeiaiue. Naia ?c aeuacacia/aieie ianoaaeiaie ie iia'yco?ii ca?a?no?iaai? ci?ie e?euee?niiai oa aeaeiaiai neeaaeo aooioei?e oe??e o oai?eo ia OAeCI. Anoaiiaeai? oaiiiaie aeinoia??iiai ca?eueoaiiy a?aenioeo aaiie?oe/ii? i?e?ioei?e, caaaeueii? e?eueeino? eieiai? i?e?ioei?e, a?aenioeo iaii?o- oa?iaiooth/i? i?e?ioei?e, a oaeiae iiyaa ?inoo eieii?e aioa?iaaeoa??e ia ieanoeieao - a?aeoeneao aeeaiei? aooioei?e oe??e ia na?aaeiaeui Aiaei, ii?yae ?c ci?iaie aeaeiaiai neeaaeo aooioei?e oe??e a a?e ia?aaaaeaiiy i?aaenoaaiee?a iaoiaaiii? oa oiiaiiiaoiaaiii? oei?e (cieioenoee noao?eieie, neiueiai?eia iaee/ea, aaiie?oe/ia nii?iiinia iaee/ea, i?ioae, i?iaaiiee no?aioieie, aioa?ieiee, aoa??o??, eeaan??ea, ae??aeaeaeiiiae?ai? a?eae ?iaeo Candida, oiui) o oai?eo ia OAeCI ei?aeththoue o cai?ioi?e aca?iicaeaaeiino? ?c nooiaiai i?eai?/aiiy ee?oeiii? ?ioiii? a?aeiia?ae? oa oaaioeeoico (?<0,05). Aeaiee oaeo aeaa iiaeeea?noue noi?ioethaaoe iiiyooy aeenaaeoa??ico oe??e, ?ic?iaeoe niin?a ae?aaiinoeee ?ioiiaeao?oeeoieo noai?a ca e?euee?nieie iieacieeaie neeaaeo aooioei?e aeeaieeo oa??a "iaeo?aeueieo" ae?eyiie oe??e. Anoaiiaeai? iaie ?aa?iia?i? ci?ie i?e?ia?ioeeiico oe??e o oai?eo ia OAeCI ia ae?eyieao, ui a?aeia?aaeathoue ?aoeaeniaaii? iae?io?io?/i? aaiaoi-eooaii? aieeae ca Caoa?'?iei - Aaaeii, aeinoia??ii a?ae??ciythoueny a?ae ci?i ia "iaeo?aeueieo" ae?eyieao, a na?aaeiueiio, ia iaeei ii?yaeie ca nooiaiai AeA oe??e. Aeniea u?euei?noue i?yiiai ei?aeyoe?eiiai ca'yceo i?ae ??aiai OI e?ia?, ?ioaineai?noth oeeoie?oe/iiai neiae?iio oa e?euee?nieie iieacieeaie i?e?ioei?e ia "aaiaoiniaoeeo?/ieo" ?aoeaeniaaiieo ae?eyieao Caoa?'?ia-Aaaea, na?ae/eoue i?i oa, ui nooi?iue aeenaaeoa??ico ia icia/aieo ae?eyieao o oai?eo ia OAeCI iiaea a?aeia?aaeaoe nooi?iue aiaeioieneeico oa nooi?iue aeoeaiino? iaoieia?/iiai i?ioeano o ia/?ioe?. Aeuacacia/ai? ianoaaeie a?aeiinyoue aeine?aeaeaiiy aooioei?e oe??e aei a??ia?aeieo ae?aaiinoe/ieo e?eoa???a OAeCI. Ca?aeii c io?eiaieie aeaieie, nooi?iue aaaeeino? iaoieia?/iiai i?ioeano a ia/?ioe?, ?ioaineai?noue aiaeioieneeico oa ?ioiiee noaoon oai?eo ia OAeCI aca?iiiia'ycai? ?c nooiaiai i?e?iaeaiaioiiai aeenaaeaino. I?e OAeCI o oai?eo an?o ee?i?/ieo a?oi anoaiiaeaii aeinoia??ia ca?eueoaiiy ai?noo cae?ca, i?ae?, ia?aaioeth, i?eaeth, naeioeth, eaaei?th oa ciaioaiiy ai?noo oeeieo oa eiaaeueoo. Cacia/aiee i?e?iaeaiaioiee aeenaaeain iiaeeaeth?oueny ii i??? c?inoaiiy ?ioaineaiino? oeeoie?oe/iiai neiae?iio, neiae?iio aiaeiaaiii? ?ioieneeaoe??, ?ioiii? iaaeinoaoiino? oai?eo ia OAeCI. Ii i??? i?ia?anoaaiiy iaoieia?/iiai i?ioeano a ia/?ioe? ca?eueoo?oueny cia/aiiy eiao?oe??io?a i?aeue/oeeie, i?eaeue/eiaaeueo, naeiaoeue/eiaaeueo, eaaei?e/eiaaeueo ? ciaioothoueny eiao?oe??ioe: cae?ci/i?aeue o 100, oeeie o 100/cae?ci. Iaeiie/aiiy a e?ia? i?eaeth, naeioeth, eaaei?th i?e iaaeinoaoi?e e?eueeino? eiaaeueoo, a oaeiae ia?aaaaeath/ee ai?no i?ae? o ii??aiyii? ?c ai?noii cae?ca ia oii? ??ceiai aeao?oeeoo oeeieo ? aeinoia??ieie oaeoi?aie i?ia?anoaaiiy iaoieia?/iiai i?ioeano a ia/?ioe?. A?aoiaoth/e c?inoaiiy e?iiia?ieneaeaoe??, i?eai?/aiiy oaeoi??a AIC, cia/iee ?ioiiee aeenaaeain ?c ia?aaaaeiei i?eai?/aiiyi ooieoe?iiaeueiiai noaio ee?oeiiiai ?ioi?oaoo oa oaaioeeoa?ii? aeoeaiino?, ianooiiei cieaeaiiyi i?ioe-aaeoa??eueiiai ?ioi?oaoo ? ?icaeoeii aeenaaeoa??ico oe??e, ia oii? c?inoaiiy ?ioaineaiino? neiae?iio aiaeiaaiii? ?ioieneeaoe??, i?ae yeeie anoaiiaeaiee aeinoia??iee ei?aeyoe?eiee ca'ycie, aeioe?eueiith, ? iaaeeeaiaioicia ei?aeoe?y aeyaeaieo ii?ooaiue ca aeiiiiiaith i?aia?ao?a aioeieneaeaioii? ae??. I?aia?aoii, ui a?aeiia?aea? oeei iio?aaai, ? aioeieneaeaio o?io?eacie?i, yeee ie canoinoaaee o eiiieaeni?e oa?ai?? oai?eo ia OAeCI o aeiaia?e aeic? 50 ia i?ioyaii 10 aei?a. I?ney eo?niaiai e?eoaaiiy o?io?eacie?iii niinoa?iaaeinue a??ia?aeia iie?a-uaiiy naiiii/oooy, ciaioaiiy iciae anoai?caoe??, aeeniaioe/ieo oa aieueiaeo i?iya?a, aeiaoyieoe?, ?ioaineaiino? oeeoie?oe/iiai oa iacaio?iaeueii-caiaeueiiai neiae?ii?a o oai?eo ia OAeCI ca cia/ii ei?iooee oa?i?i (?<0,05) o ii??aiyii? ?c a?oiith oai?eo, ye? io?eioaaee a yeino? aaiaoii?ioaeoi?a anaioe?aea-oi?oa. Ii?yae ?c aeinoia??iei ciaioaiiyi iieaciee?a ai?noo i?ii?aeieo oa e?ioeaaeo i?iaeoeo?a IIE (IAeA, AeE, ENO, ?IC) (p<0,05), c?inoaiiyi ai?noo AA a ne?iaaooe? e?ia? (p<0,05), aeoeaiino? oa?iaio?a NIAe oa A6OAeA (p<0,05), a oaeiae a?eueo cia/iiai aeinoia??iiai ciaioaiiy ni?aa?aeiioaiiy IAeA/NIAe (p<0,05) o oai?eo iniiaii? a?oie o ii??aiyii? c aeeiai?/ieie iieacieeaie a eiio?ieuei?e a?oi?, o?io?eacie?i ni?ey? ciaioaiith ?ioaineaiino? aiaeioieneeico. Aeieacii iiooaeii? aeaoieneeoth/i? ae?? o?io?eacie?io ? ciaioaiiy OI a?aeiia?aeii ia 23,5% (p<0,001) i?e OAIA, ia 30,2% (p<0,001) o oai?eo ia OAIA oa ia 36,1% (p<0,001) o oai?eo ia OeI, i?ioe 18,3% (p<0,001), 24,9% (p<0,001), 28,5% (p<0,001) a?aeiia?aeii o oai?eo ia OAIA, OAIA, OeI eiio?ieueii? a?oie. Iiooaei? aeac?ioieneeaoe?ei? aeanoeaino? o?io?eacie?io i?aeoaa?aeaeothoueny aeinoia??iei ca?eueoaiiyi ee??aino aiaeiaaiieo oienei?a o ii??aiyii? c iieacieeii aei e?eoaaiiy a?aeiia?aeii ia 65,2% (p<0,001) i?ioe iieacieea o oai?eo ia OAIA o eiio?ie? 13,0% (p<0,05). Aeeiai?/i? iieacieee No o a?oiao oai?eo ia OAIA oa OeI iniiaii? a?oie c?inoaee a?eueo ?ioaineaii ? neeaee a?aeiia?aeii 183,3% (p<0,001) oa 317,6% (p<0,001) i?ioe 45,8% (p<0,001) oa 111,8% (p<0,001) o eiio?ieueieo a?oiao. Ioaea, naia iiooaeieie aeac?ioieneeaoe?eieie oa aioeieneaeaioieie aeanoe-ainoyie iiaeia iiynieoe ae?aaeaiee ?ioiiiiaeoethth/ee aoaeo o?io?eacie?io. I?aeoaa?aeaeaiyi oeueiai oaeoo ? ca?eueoaiiy aaniethoiiai oa a?aeiiniiai ai?noo e?ioioeeo?a a ia?eoa?e/i?e e?ia? (?<0,05), aeinoia??ia ca?eueoaiiy a?aeiinii? e?eueeino? O-e?ioioeeo?a (?<0,05), aeoeaieo O-e?ioioeeo?a (?<0,05), O-oaeia??a (?<0,05), O-noi?ani??a (?<0,05), ciaioaiiy cia/aiiy ??? (?<0,05) ii i??? ciaioai-iy nooiaiy aiaeioieneeico o ii??aiyii? ?c iieacieeii aei e?eoaaiiy o oai?eo iniiaii? a?oie, /iai ie ia niinoa?iaaee o oai?eo eiio?ieueii? a?oie. Anoaiiaea-iee a?eueo ae?aaeaiee aoaeo o?io?eacie?io ia a?aeiiaeaiiy i?eaii/aii? oaaioee-oa?ii? aeoeaiino? iaeo?io?e?a o ii??aiyii? ?c o?aaeeoe?eiith oa?ai??th (p<0,05). I?aeaeuaiiy ooieoe?iiaeueii? aeoeaiino? oaaioeeoa?ii? eaiee ?ioi?oaoo, a oaeiae a?aeiinia aaeueioaaiiy i?aeaeuaii? ?ioiiaeiaoe?ineioaoe/ii? aeoeaiino? A-e?ioioeeo?a i?ae aieeaii oa?ai?? ?c caeo/aiiyi o?io?eacie?io i?ecaaea aei a?eueo cia/iiai cieaeaiiy ai?noo Oe?E o oai?eo ia OAIA oa OeI iniiaii? a?oie o ii??aiyii? c eiio?ieai (p<0,05). I?ae aieeaii o?io?eacie?io a?eueo cia/ii ciaioo?oueny nooi?iue AeA oe??e, a na?aaeiueiio, ia iaeei ii?yaeie, o ii??aiyii? ?c aeeiai?/ieie iieacieeaie o eiio?ie?, aea a?aenioie ae?i?iaoe?? o?aiceoii? i?e?ioei?e a??ia?aeiee ieae/ee. Iaeaea, canoinoaaiiy o?io?eacie?io o eiiieaeni?e oa?ai?? oai?eo ia OAeCI ? iaoiaaiaoe/ii iaa?oioiaaiei ? aeioe?eueiei c iaoith onoiaiiy neiae?iio aiaeiaaiii? ?ioieneeaoe??, i?aeneeaiiy ooieoe?iiaeueii? aeoeaiino? nenoaie i?ioe?aaeeeaeueiiai caoenoo, ?ioiiei?aeoe??. AENIIAEEAENIIAEE 1.I?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee i?aeaeuo?oueny ?ioainea-i?noue aiaeioieneeico o i?yi?e aca?iicaeaaeiino? ?c i?iyaaie oeeoie?oe/iiai, oieanoaoe/iiai, iacaio?iaeueii-caiaeueiiai neiae?ii?a, ia/?ieiai-ee?oeiii? iaaeinoaoiino?, ui ? oaeoi?ii i?ia?anoaaiiy iaoieia?/iiai i?ioeano a ia/?ioe?. 2.Caaino?aiiy o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee noi?iaiaeaeo?oueny i?aeaeuaiiyi ?ioaineaiino? i?ioean?a a?eueii?aaeeeaeueiiai ieeniaiiy e?i?ae?a, yea i?ia?ano? o i?yi?e caeaaeiino? a?ae ae?aaeaiino? iciae oeeoie?co aaiaoioeeo?a oa nooiaiy aaaeeino? aiaeiaaiii? ?ioieneeaoe??. Iaeiie/aiiy o e?ia? i?ii?aeieo oa e?ioeaaeo i?iaeoeo?a A?IE ? iaeiei ?c aeaea?ae aiaeioieneeico. 3.I?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee a?aeaoaa?oueny aeaeiiiainaoe?y ooieoe?iioaaiiy nenoai i?ioe?aaeeeaeueiiai caoenoo: cieaeaiiy o e?ia? ai?noo a?aeiiaeaiiai aeooao?iio, i?eai?/aiiy aeoeaiino? noia?ieneaeaeen-iooace oa aetheici-6-oinoaoaeaa?ae?iaaiace, ye? aiaeii/an, ? eeth/iaeie eaieaie i?e?iaeiuei? nenoaie aeaoieneeaoe??. Iaoai?ciii eiiiainaoe?? i?aeaeuaii? aeoeaiino? i?ioean?a A?IE oa i?ia?anoth/iai aiaeioieneeico ? c?inoaiiy aeoeaiino? aeooao?ii-ia?ieneaeace, aeooao?ii?aaeoeoace oa aeooao?ii-S-o?ainoa?ace. 4.Iaeiio?ieueiaaia ?ioaineo?eaoe?y i?ioean?a A?IE, i?ia?anoth/ee nenoaiiee aiaeioieneeic, oeeoie?c aaiaoioeeo?a, oieanoac, ia?inoath/a ia/?ieiai-ee?oeiia iaaeinoaoi?noue i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee ni?eythoue ?icaeoeo aoi?eiii? ?ioiii? iaaeinoaoiino?, i?eai?/aiith ?ioii?aaeoeaiino? i?aai?cio oa i?ioeaaeoa??aeueiiai ?ioi?oaoo, ?icaeoeo ?ioaeoe?eieo oneeaaeiaiue, aeenaaeoa??ico oe??e. 5.E?euee?niee oa aeaeiaee neeaae aooioei?e oe??e ? ?iaeeeaoi?ii ?ioii?aaeoea-iino? i?aai?cio, ca yeei iiaeia anoaiiaeoe nooi?iue ?ioiii? iaaeinoaoiino?. ?aa?i-ia?iee aeenaaeoa??ic oe??e, anoaiiaeaiee ia ?aoeaeniaaiieo aaiaoiniaoeeo?/ieo ae?eyieao Caoa?'?ia-Aaaea ? iaeiei ?c e?eoa???a ae?aaiinoeee oa i?iaiicoaaiiy ia?a-a?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee. Nooi?iue ?aa?iia?iiai aeenaaeoa-??ico ciaoiaeeoueny o i?yi?e aca?iicaeaaeiino? a?ae nooiaiy aaaeeino? aiaeioieneeico. 6.I?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee i?aeaeuo?oueny ai?no o e?ia? cae?ca, i?ae?, ia?aaioeth, i?eaeth, naeioeth, eaaei?th oa cieaeo?oueny ai?no oeeieo oa eiaaeueoo. Nooi?iue i?e?iaeaiaioiiai aeenaaeaino iiaeeaeth?oueny ?c ae?aaeai?noth oeeoie?oe/iiai neiae?iio, neiae?iio ia/?ieiai-ee?oeiii? iaaeinoaoiino? oa aiaeioieneeico, ? oaeoi?ii i?ia?anoaaiiy iaoieia?/iiai i?ioeano a ia/?ioe?; ni?ey? i?eai?/aiith ooieoe?iiaeueii? caeaoiino? O-e?ioioeeo?a oa oaaioeeoa?ii? aeoeaiino? nenoaie iie?ii?oii-yaea?ieo eaeeioeeo?a. 7.O?io?eacie?i o eiiieaeni?e oa?ai?? oai?eo ia o?ii?/i? aeeooci? caoai?thaai-iy ia/?iee i?iyaey? iiooaeiee aeac?ioieneeaoe?eiee oa ?ioiiiiaeoethth/ee aoaeoe, ni?ey? i?aeneeaiith i?ioeaaeoa??aeueiiai ?ioi?oaoo oa ciaioaiith nooiaiy aeenaaeoa??ico oe??e. Aeeth/aiiy o?io?eacie?io a eiiieaenia e?eoaaiiy o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee ni?ey? aeinyaiaiith no?eei? ee?i?ei-a?io?i?/ii? ?ai?n?? iniiaiiai oa noiooi?o caoai?thaaiue, nei?i/aiith oa?i?i?a e?eoaaiiy. I?AEOE*I? ?AEIIAIAeAOe??I?AEOE*I? ?AEIIAIAeAOe?? 1.O oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee aeioe?eueiei ? aecia/aiiy aeo?aeiiai nooiaiy aiaeioieneeico ca iieacieeaie: oiene/iino? ieacie e?ia?, oiene/iino? na/?, ee??aino aiaeiaaiieo oienei?a, ai?noo o e?ia? na?aaeiueiiieaeoey?ieo iaioeae?a oa iaeiiiaiai ae?aeueaeaa?aeo; aeine?aeaeaiiy aeaiaio?a nenoaie i?ioe?aaeeeaeueiiai caoenoo: nenoaie aeooao?iio, aeoeaiino? NIAe, A-6-OAeA, a oaeiae ni?aa?aeiioaiiy IAeA/NIAe. Aeeiai?ea oeeo iieaciee?a ? e?eoa???i aeai?o ?aoe?iiaeueii? e?eoaaeueii? oaeoeee oa aoaeoeaiino? aeac?ioieneeaoe?eii? oa?ai??, ine?eueee ia?ea?e neiae?ii?a oeeoie?co, oieanoaco, iacaio?iaeueiiai caiaeaiiy ia caaaeaee aeacothoue ia ?ioaineai?noue aiaeioieneeico. 2.I?e ioe?ioe? ?ioaineaiino? neiae?iio aiaeiaaiii? ?ioieneeaoe?? aeioe?eueii aeei?enoiaoaaoe eeaneo?eaoe?th aiaeioieneeico ca ?ioaa?aeueieie e?eoa??yie: oiene/i?noue ieacie e?ia? (OI), ai?no na?aaeiueiiieaeoey?ieo iaioeae?a (NII) oa iaeiiiaiai ae?aeueaeaa?aeo (IAeA) a e?ia?: ? nooi?iue (eaaeee): OI - 110-149 o.i./ie, IAeA - 4,0-5,7 ieiieue/e, NII - 0,288-0,315 o.i.; ?? nooi?iue (na?aaeiuei? aaaeeino?): OI - 150-174 o.i./ie, IAeA - 5,8-7,3 ieiieue/e, NII - 0,316-0,368 o.i.; ??? nooi?iue (aaaeeee): OI - 175-200 o.i./ie, IAeA - 7,4-8,5 ieiieue/e, NII - 0,369-0,412 o.i.; ?V nooi?iue (ae?ae aaaeeee): OI - a?eueoa 200 o.i./ie, IAeA - a?eueoa 8,5 ieiieue/e, NII - a?eueoa 0,412 o.i. 3.I?e?ia?ieia?/ia aeine?aeaeaiiy noaio aooioei?e iaeo?aeueieo ae?eyiie oe??e ? ?ioi?iaoeaiei aeey anoaiiaeaiiy nooiaiy ?ioiii? iaaeinoaoiino?, ca?aeii ?c cai?iiiiiaaiith eeaneo?eaoe??th aeenaaeoa??ico oe??e, oa i?iaiicoaaiiy ?icaeoeo ?ioaeoe?eieo oneeaaeiaiue. 4.Aecia/aiiy aeaeiaiai oa e?euee?niiai neeaaeo i?e?ioei?e aeeaieeo oa??a oe??e ia "?aoeaeniaaiieo" aaiaoiniaoeeo?/ieo ae?eyieao Caoa?'?ia-Aaaea ? ae?aaiinoe/iei oa i?iaiinoe/iei e?eoa??yie ia?aa?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee, a oaeiae e?eoa???i aoaeoeaiino? e?eoaaiiy. 5.Eiiieaenia aeine?aeaeaiiy i?e?iaeaiaio?a: cae?ca, i?ae?, oeeieo, ia?aaioeth, i?eaeth, eiaaeueoo, naeioeth oa eaaei?th - o e?ia? oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee ? aaaeeeaei aeey a?aooaaiiy iaoiaaiaoe/ii? ?ie? oiene/ieo aieea?a aaaeeeo iaoae?a ia ia?aa?a aeaii? iaoieia??, a oaeiae aeey ?ic?iaee aaeaeaaoieo oa?aiaaoe/ieo caoiae?a (ae?i?iaoe?? iaaeeeoeiaeo oa iiiiaiaiiy aeao?oeeoieo) i?e aeeni?e?iaeaiaioic?. 6.C aeac?ioieneeaoe?eiith, i?ioeieneaeaioiith, iaia?aiinoaa?e?coth/ith, ?ioiiiiaeoethth/ith iaoith a eiiieaeni?e oa?ai?? neiae?iio aiaeiaaiii? ?ioieneeaoe?? i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee aeioe?eueii canoiniaoaaoe o?io?eacie?i ca noaiith: o oai?eo ?c ?-i nooiaiai aaaeeino? aiaeioieneeico - ii 2 ie 2,5% ?ic/eio aioo??oiueii'ycaai 1 ?ac ia aeiao i?ioyaii 10 aei?a; o oai?eo ?c ??-i nooiaiai aiaeioieneeico - ii 2 ie 2,5% ?ic/eio aioo??oiueiaaiii no?oieiii (iia?eueii) 1 ?ac ia aeiao i?ioyaii 10 aei?a; o oai?eo ?c ???-i nooiaiai - ii 2 ie 2,5% ?ic/eio aioo??oiueiaaiii no?oieiii (iia?eueii) 2 ?ace ia aeiao i?ioyaii 10 aei?a; o oai?eo ?c ?V-i nooiaiai - ii 2 ie 2,5% ?ic/eio aioo??oiueiaaiii no?oieiii (iia?eueii) 3 ?ace ia aeiao aai ii 3 ie 2 ?ace ia aeiao i?ioyaii 10 aei?a. I?e ciaioaii? iieaciee?a aiaeiaaiii? ?ioieneeaoe?? aei cia/aiue OI - 110 o.i./ie, IAeA - 4,0 ieiieue/e, oa NII - 0,288 o.i. o?io?eacie?i ne?ae i?ecia/aoe ii 1 ie 1% ?ic/eio aioo??oiueii'ycaai 1 ?ac ia aeiao aai ii 0,1 a 3 ?ace ia aeaiue a oaaeaoiaai?e oi?i?. Eo?n e?eoaaiiy - 2-3 i?nyoe?. Ae?oeiaaii ?iaioe ca oaiith aeena?oaoei?Ae?oeiaaii ?iaioe ca oaiith aeena?oaoei? 1. Oooe?ia I.N. Aiaeioieneeic a iaoiaaiac? o?ii?/ieo aaiaoeo?a oa eiai ei?aeoe?y o?io?eacie?iii // Aoeiaeinueeee iaaee/iee a?niee.- 1998.- O.2, ?2.- N. 99-105. 2. Oooe?ia I.N. Iaoiaaiaoe/ia iaa?oiooaaiiy aeac?ioieneeaoe?eii? oa i?ioeieneaeaioii? oa?ai?? a eiiieaeniiio e?eoaaii? o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee // E?ea?nueea ni?aaa. A?a/aaiia aeaei.- 1998.- ? 6.-N. 51-56. (niiaaao.: Eieiii?oeue I.TH.) 3. Oooe?ia I.N. Ioe?iea noaio ?ioii?aaeoeaiino? a ae?aaiinoeoe? oa i?iaiicoaaii? ia?aa?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee // Aaeeoeueeee e?ea?nueeee a?niee.- 1998.- O.5, ? 1.- N. 83-87. 4. Oooe?ia I.N. Aiaeioieneeic o oai?eo ia o?ii?/i? aaiaoeoe oa aeaye? niiniae eiai ei?aeoe?? // Iaoa??aee XIV c'?caeo oa?aiaao?a Oe?a?ie.- Ee?a.- 1998.- N. 465-467. (niiaaao.: Eiiia/oe A.I., O?iyi I.O., O?iyi A.I., Ao?aiaiei I.A.) 5. Oooe?ia I.N. Iaoiaaiaoe/i? iniaeeaino? ?icaeoeo ?ioiiaeao?oeeoieo noai?a o oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee oa aeaye? niiniae ?ioiiei?aeoe?? // Iaoa??aee XIV c'?caeo oa?aiaao?a Oe?a?ie.- Ee?a.- 1998.- N. 464-465. 6. Oooeeia I.N. Aeeyiea yiaeiaaiiie eioieneeaoeee ia eiioiiue noaoon aieue-iuo o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie // ?inneeneee aeo?iae aano?iyioa?ieiaee, aaiaoieiaee, eieii?ieoieiaee. I?eeiaeaiea ? 4.- Iineaa.- 1997.- O. 7, ? 5.- N. 164-165. (niaao.: Oeiioaaa A.A., Aioioee/oe I.I., Iiaeoeeee N.A.) 7. Oooe?ia I.N. Iniaeeaino? ?ioiiiai noaoono oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee c o?aooaaiiyi ?ioaineaiino? aiaeioieneeico // Oace aeiiia?aeae Ae?oaiai Oe?a?inueeiai aano?iaioa?ieia?/iiai oeaeiy. -Aei?i?iiao?ianuee.- 1997.- N. 140-141. 8. Oooeeia I.N. Eioi?iaoeaiinoue enneaaeiaaiey ?aaeiia?iiai iee?iaei-oeaiica eiaee a aeeaaiinoeea e i?iaiice?iaaiee oa/aiey o?iie/aneeo aeeooociuo caaieaaaiee ia/aie // ?inneeneee aeo?iae aano?iyioa?ieiaee, aaiaoieiaee, eieii?ieoieiaee. I?eeiaeaiea ?3.- Iineaa.- 1996.- O. 6, ? 4.- N. 200. 9. Oooe?ia I.N. Ioe?iea oa i?iaiicoaaiiy ia?aa?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee c o?aooaaiiyi ae?? oaeoi??a aeieia?/ii? aa?an?? // Iaoa??aee i?aeia?iaeiiai neiiic?oio "Aeooaeuei? ieoaiiy iaaee/ii? aeiiiiiae ianaeaiith".- *a?i?aoe?-Engelholm.- 1996.- N. 143-144. (niiaaao. Eiiia/oe A.I.). 10. Oooe?ia I.N. Noai i?e?ia?ioeaiico oa aeayeeo oaeoi??a ?ioi?oaoo a aeeiai?oe? e?eoaaiiy o oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee // Iaoa??aee iaoeiai-i?aeoe/ii? eiioa?aioe?? "Aeooaeuei? i?iaeaie iaaee/iiai ianeoaiaoaaiiy i?aoethth/eo ia cae?cie/iiio o?ainii?o?. Aeieia?y oa noai caei?ia'y ianaeaiiy a no/anieo oiiaao. Eaco?noeea, aia?aoi? oa ?ino?oiaioaeuei? iaoiaee ae?aaiinoeee oa e?eoaaiiy caoai?thaaiue ethaeeie".- Oaeai?iae.- 1996.- N. 159-160. 11. Oooe?ia I.N. Ee?i?/ia oa i?iaiinoe/ia cia/aiiy canoinoaaiiy iaoiaeo aaeoa??aeueieo a?aeoene?a o oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee // Iaoa??aee ? iaoeiai-i?aeoe/ii? eiioa?aioe?? ii/aoeoth/eo iaoeiaoe?a oa iieiaeeo a/aieo Aoeiaeie "A?ieia?y, iaaeeoeeia, aeieia?y".- *a?i?aoe?.- 1996.- N. 79-80. 12. Oooe?ia I.N. Ae?aaiinoe/ia oa i?iaiinoe/ia cia/aiiy aeine?aeaeaiiy aooioei?e oe??e i?e o?ii?/ieo aeeoocieo caoai?thaaiiyo ia/?iee o oai?eo c??eiai, iioeeiai oa noa?a/iai a?eo // Iaoa??aee Ieaioio i?aae?iiy Oe?a?inueeiai iaoeiaiai oiaa?enoaa aa?iioieia?a ? aa??ao??a "O?c?ieia?y ? iaoieia?y i?aai?a o?aaeaiiy o in?a iioeeiai oa noa?a/iai a?eo".- *a?i?aoe?.- 1996.- N. 130-131. 13. Oooeeia I.N. Aeeaaiinoe/aneia e i?iaiinoe/aneia cia/aiea enneaaeiaaiey aooioei?u eiaee o aieueiuo n o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie // Iaoa?eaeu Oaeuee-neiiiceoia ? 92 "Iiaua iai?aaeaiey a aaiaoieiaee".- Naieo-Iaoa?ao?a.- 1996.- N. 408. (niaao. Eiiia/oe A.I.) 14. Oooe?ia I.N. Ioe?iea noaio ?ioii?aaeoeaiino? oa canoinoaaiiy iaoiaeo aaeoa??aeueieo a?aeoene?a ye aeiaeaoeiaiai ae?aaiinoe/iiai oanoo o oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee // Iaoa??aee neiiic?oio "Aeooaeuei? ieoaiiy ?aaa?e?oaoe?? aano?iaioa?ieia?/ieo oai?eo".- *a?i?aoe?.- 1996.- N. 385-388. 15. Oooe?ia I.N. Cia/aiiy aea/aiiy aooioei?e oe??e, ye ?iaeeeaoi?a ?ioii?aaeoeaiino? i?aai?cio i?e o?ii?/ieo caoai?thaaiiyo ia/?iee // Iaoa??aee Ia?oiai Oe?a?inueeiai eiia?ano aano?iaioa?ieia?a.-Aei?i?iiao?ianuee.- 1995.- N. 71-72. (niiaaao. Eiiia/oe A.I.) ?aoe?iiae?caoi?nuee? i?iiiceoe?? 1. Oooe?ia I.N. Iaoiaeeea aecia/aiiy nooiaiy ?ioiiaeao?oeeoo. ? 35/97 a?ae 10.12.97 Aoeiaeinueei? aea?aeaaii? iaaee/ii? aeaaeai??. Iaoiaee/i? ?aeiiaiaeaoe?? 1. Oooe?ia I.N. I?iaiicoaaiiy ia?aa?ao o?ii?/ieo caoai?thaaiue ia/?iee ? aeia/iiai i?oo?a oa ei?aeoe?y ii?ooaiue i?ioe?aaeeeaeueiiai caoenoo ? i?e?ioee?eoeyoe?? o oai?eo ??ciiai a?eo // IIC Oe?a?ie.- *a?i?aoe?.- 1997.- 31 n. (ni?aaaoi?e: Eieiii?oeue I.TH., Oaae?a I.?., Aie/oe ?.?., Aioio?e/oe I.I., Ai?a?aeea I.N., Oeiio??a A.A., Oiaei??ei E.Ae., Oi??eia ?.?.). AIIOAOe?ssAIIOAOe?ss Oooe?ia I.N. Aiaeiaaiia ?ioieneeaoe?y, noai i?e?ia?ioeaiico oa aeayeeo oaeoi??a ?ioi?oaoo o oai?eo ia o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee. ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.02. - aioo??oi? oai?iae. - ?aaii - O?aie?anueea aea?aeaaia iaaee/ia aeaaeai?y, ?aaii - O?aie?anuee, 1999. Iniiai? iieiaeaiiy aeena?oaoe?? i?noyoue ii??aiyeueiee aiae?c ee?i?/ieo, a?io?i?/ieo, ?ioiieia?/ieo, i?e?ia?ieia?/ieo, oieneeieia?/ieo iieaciee?a i?e ??cieo aa??aioao ia?aa?ao o?ii?/ieo aeeoocieo caoai?thaaiue ia/?iee oa ?o ni?aa?aeiioaiiy a caeaaeiino? a?ae nooiaiy aaaeeino? neiae?iio aiaeiaaiii? ?ioieneeaoe??. Aeena?oaoe?y i?enay/aia aea/aiith iniaeeainoae aeiee?i?/ieo oa iai?oanoieo oi?i aiaeioieneeico o 140 oai?eo ia OAeCI a caeaaeiino? a?ae ?ioaineaiino? i?ioean?a ia?ieneaeiiai ieeniaiiy e?i?ae?a, noaio nenoaie i?ioe?aaeeeaeueiiai caoenoo, oaeoi??a nenoaiiiai ?ioi?oaoo oa ianiaoeeo?/ii? ?acenoaioiino?, e?euee?niiai oa aeaeiaiai neeaaeo aooioei?e oe??e, ai?noo a e?ia? aeayeeo i?e?iaeaiaio?a. Anoaiiaeaii oa iaa?oioiaaii iiaeeea?noue oa?iaeieia?/ii? ei?aeoe?? aiaeioieneeico, a?ia?e?iiia?ieneaeaoe?? oa aoi?eiii? ?ioiii? iaaeinoaoiino? ca aeiiiiiaith aioeieneaeaioo o?io?eacie?io. Eeth/ia? neiaa: o?ii?/i? aeeooci? caoai?thaaiiy ia/?iee, aiaeioieneeic, a?eueii?aaeeeaeueia ieeniaiiy e?i?ae?a, i?ioe?aaeeeaeuei? nenoaie, ?ioi?oao, aooi-oei?a oe??e, i?e?iaeaiaioe, o?io?eacie?i. AIIIOAOeEssAIIIOAOeEss Oooeeia I.N. Yiaeiaaiiay eioieneeaoeey, ninoiyiea iee?iaeioeaiica e iaeioi?uo oaeoi?ia eiioieoaoa o aieueiuo o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie.- ?oeiienue. Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.02.- aioo?aiiea aieacie.- Eaaii-O?aieianeay ainoaea?noaaiiay iaaeeoeeineay aeaaeaiey, Eaaii - O?aieiane, 1999. A ?aaioa i?eaaaeaiu ?acoeueoaou eeeieei-eaai?aoi?iiai enneaaeiaaiey 140 aieueiuo o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie ae?oniie e niaoaiiie (ae?onii-oiene/aneie) yoeieiaee a oaca eioaa?aoeee ae?ona A, n?aaee eioi?uo 42 aieueiuo no?aaeaee o?iie/aneei aaiaoeoii n ieieiaeueiie aeoeaiinoueth, 55 aieueiuo o?iie/aneei aaiaoeoii n oia?aiiie aeoeaiinoueth e 43 aieueiuo aeoeaiui oee??icii ia/aie. Aeenna?oaoeey iinayuaia eco/aieth iniaaiiinoae aeieeeie/aneeo e iaieoanoiuo oi?i yiaeioieneeica o aieueiuo o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie a caaeneiinoe io eioaineaiinoe i?ioeannia ia?aeeniiai ieeneaiey eeieaeia, ninoiyiey iaeioi?uo oaeoi?ia aioe?aaeeeaeueiie caueou, nenoaiiiai eiioieoaoa e ianiaoeeoe/aneie ?acenoaioiinoe, ninoaaa eiaeiie iee?ioei?u, niaea?aeaiey a e?iae iaeioi?uo iee?iyeaiaioia. Onoaiiaeaii, /oi iaino?aiea o?iie/aneeo aeeooociuo caaieaaaiee ia/aie nii?iaiaeaeaaony oneeaieai eioaineaiinoe yiaeioieneeica a i?yiie caaeneiinoe io au?aaeaiiinoe oeeoieeoe/aneiai, oieanoaoe/aneiai, iacaioeiaeueiiainiaee-oaeueiiai neiae?iia, ia/?ii/iieeaoi/iie iaaeinoaoi/iinoe, /oi yaeyaony oaeoi?ii i?ia?anne?iaaiey iaoieiae/aneiai i?ioeanna a ia/aie. I?e o?iie/aneeo aeeooociuo caaieaaaieyo ia/aie iaaethaeaaony oneeaiea eioaineaiinoe i?ioeannia naiaiaeii?aaeeeaeueiiai ieeneaiey eeieaeia, eioi?ay i?ia?anne?oao a i?yiie caaeneiinoe n au?aaeaiiinoueth oeeoieeca aaiaoioeeoia e ni noaiaiueth oyaeanoe eioieneeaoeeiiiiai neiae?iia. Iaeiieaiea a e?iae i?iia-aeooi/iuo (eciee?iaaiiua aeaieiua nayce, aeeaiiaua eiiuthaaou, eaoiaeeaiu e nii?yae?iiua o?eaiu) e eiia/iuo (iaeiiiaue aeeaeueaeaaeae) i?iaeoeoia ia?a-eeniiai ieeneaiey eeieaeia yaeyaony iaeiei ec enoi/ieeia yiaeioieneeica. Aeaaiaea?y iaee/eth i?yiie ei??aeyoeeiiiie nayce aunieie neeu iaaeaeo oie-ne/iinoueth ieaciu e?iae, niaea?aeaieai a e?iae n?aaeiaiieaeoey?iuo iaioeaeia e iaeiiiaiai aeeaeueaeaaeaea onoaiiaeaiiie o aieueiuo o?iie/aneeie aeeooociuie caaieaaaieyie ia/aie auea ?ac?aaioaia eeanneoeeaoeey yiaeioieneeica ii noaiaie oyaeanoe n eniieueciaaieai iniiaiuo eioaa?aeueiuo e?eoa?eaa eioieneeaoeee. Ii ia?a ia?inoaiey yiaeioieneeica o ianeaaeiaaiuo aieueiuo iaaethaeaaony aeaeiiiainaoeey ooieoeeiie?iaaiey nenoai aioe?aaeeeaeueiie caueou: nieaeaiea niaea?aeaiey a e?iae ainnoaiiaeaiiiai aeooaoeiia, oaiaoaiea aeoeaiinoe noia?-ieneaeaeeniooacu e aetheici-6-oinoaoaeaaeae?iaaiacu, eioi?ua iaeiia?aiaiii yaeythony eeth/aauie caaiueyie i?e?iaeiie nenoaiu aeaoieneeaoeee. Eiiiainaoeey iiauoaiiie aeoeaiinoe i?ioeannia naiaiaeii?aaeeeaeueiiai ieeneaiey eeieaeia e i?ia?ane?othuaai yiaeioieneeica iaania/eaaaony ca n/ao aic?inoaiey aeoea-iinoe aeooaoeiiia?ieneaeacu, aeooaoeii?aaeoeoacu e aeooaoeii-S-o?ainoa?acu. Iaeiio?iee?iaaiiay eioaineoeeaoeey i?ioeannia naiaiaeii?aaeeeaeueiiai ieeneaiey eeieaeia, i?aiaeaaeaiea eaoaaiee/aneeo i?ioeannia, oieanoac, ia?inoathuay ia/?ii/iieeaoi/iay iaaeinoaoi/iinoue, i?ia?ane?othuee nenoaiiue yiaeioieneeic i?e o?iie/aneeo aeeooociuo caaieaaaieyo ia/aie niinianoaotho ?acaeoeth aoi?e/iie eiioiiie iaaeinoaoi/iinoe, oaiaoaieth eiioii?aae-oeaiinoe i?aaiecia e i?ioeaiaaeoa?eaeueiiai eiioieoaoa, ?acaeoeth eioae-oeeiiiuo ineiaeiaiee, aeenaaeoa?eica eiaee. Eiee/anoaaiiue e aeaeiaie ninoaa eiaeiie aooioei?u yaeyaony eiaeeeaoi?ii eiioii?aaeoeaiinoe i?aaiecia, n iiiiuueth eioi?iai iiaeii onoaiiaeoue noaiaiue eiioiiie iaaeinoaoi/iinoe. ?aaei-ia?iue aeenaaeoa?eic eiaee, onoaiiaeaiiue ia ?aoeaeniaaiiuo aaiaoi-niaoee-oe/aneeo o/anoeao Caoa?ueeia-Aaaea yaeyaony iaeiei ec aeeaaiinoe/aneeo e i?iaiinoe/aneeo e?eoa?eaa i?e o?iie/aneeo aeeooociuo caaieaaaieyo ia/aie. Noaiaiue ?aaeiia?iiai aeenaaeoa?eica iaoiaeeony a i?yiie acaeiicaaeneiinoe io noaiaie oyaeanoe yiaeioieneeica. I?e o?iie/aneeo aeeooociuo caaieaaaieyo ia/aie aeinoiaa?ii iiauoaaony niaea?aeaiea a e?iae aeaeaca, iaaee, ia?aaioea, ieeaey, naeioea, eaaeiey e nieaeaaony niaea?aeaiea oeeiea e eiaaeueoa. Noaiaiue iee?iyeaiaioiiai aeenaaeeaina oaeoaeyaony a i?yiie caaeneiinoe io noaiaie oyaeanoe yiaeioieneeica, eioai-neaiinoe oeeoieeoe/aneiai neiae?iia, ia/?ii/iieeaoi/iie iaaeinoaoi/iinoe e yaeyaony oaeoi?ii i?ia?anne?iaaiey iaoieiae/aneiai i?ioeanna a ia/aie, a oaeaea niinianoaoao oaiaoaieth ooieoeeiiaeueiie niiniaiinoe O-eeioioeeoia e oaaioeeoa?iie aeoeaiinoe nenoaiu iieeii?oiiyaea?iuo eaeeioeeoia. Onoaiiaeaii e iainiiaaii aiciiaeiinoue oa?iaeieiae/aneie ei??aeoeee yiaei-oieneeica, aeia?eeiiia?ieneaeaoeee e aoi?e/iie eiioiiie iaaeinoaoi/iinoe n iiiiuueth aioeieneaeaioa oeio?eacieeia. Eeth/aaua neiaa: o?iie/aneea aeeooociua caaieaaaiey ia/aie, yiaeioieneeic, naiaiaeii?aaeeeaeueiia ieeneaiea eeieaeia, aioe?aaeeeaeueiua nenoaiu, eiioieoao, aooioei?a eiaee, iee?iyeaiaio, oeio?eacieei. SUMMARYSUMMARY Khukhlina O. S. Endogenous intoxication microbiocenosis and some immune factors status in chronic diffuse liver diseases patients. Manuscript. Dissertation on competition of a scientific degree of the Candidate of Medical Sciences on a speciality - 14.01.02.- internal diseases.- Ivano-Frankivsk State Medical Academy, Ivano-Frankivsk,1999. The main thesis of dissertation contain the comperative analysis of clinical, biochemical, immunological, toxicological data in 140 patients with different clinical variants of chronic diffuse liver diseases depending on the degree of endotoxicosis. Dissertation is devoted to learning of endotoxicose especialities in chronic liver diseases patients in depending on intencity of lipoperoxidation process, functional status of antiradical protectors, some factors of immune system and nonspecific resistence, skin microbiocenosis and blood conclusion of some microelements. The possibility of pharmacological correction of endotoxicose, hyperlipo-peroxidation and second immune insufficiency with the help of antiradical protector - thiotriazoline is reasonable and proved. Key words: chronic diffuse liver diseases, endotoxicosis, free radical lipid peroxidation, antiradical protective system, immunity, skin microbiocenosis, microelement, thiotriazoline.

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