2

15

IAOe?IIAEUeIA AEAAeAI?ss IAOE OE?A?IE

?INOEOOO AENIA?EIAIOAEUeII? IAOIEIA??, IIEIEIA?? I ?AAe?IA?IEIA??
?i.?.?.EAAAOeUeEIAI

I?I?NOA?NOAI IOI?IIE CAeI?IA’ss OE?A?IE

OE?A?INUeEEE IAOEIAI-AeINE?AeIEE ?INOEOOO IIEIEIA?? OA
?AAe?IEIA??

IINEAEAIEI Ieaenaiae? Aaneeueiae/

OAeE 616.33-006.6-089

Ae?AAIINOEEA, I?IO?EAEOEEA OA E?EOAAIIss ?AII?O I?NEssIIA?AOe?EIEO
AIOO??OIUeI*A?AAIEO ONEEAAeIAIUe I?E O??O?A?*IIIO E?EOAAII? ?AEO OEOIEA

(Ee?i?ei-eaai?aoi?ia aeine?aeaeaiiy)

14.01.07 — iieieia?y

AAOI?AOA?AO

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa
iaaee/ieo iaoe.

Ee?a — 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia ia eaoaae?? iieieia?? Oe?a?inueei? iaaee/ii?
noiiaoieia?/ii? aeaaeai??.

Iaoeiaee ea??aiee -aeieoi? iaaee/ieo iaoe, i?ioanip

Oaeaoei Iao?i Aaiaaeeeoiae/,

caa?aeoaa/ eaoaae?e iieieia?? Oe?a?inueei?
iaaee/ii? noiiaoieia?/ii? aeaaeai??

IIC Oe?a?ie

Io?oe?ei? iiiiaioe -aeieoi? iaaee/ieo iaoe, i?ioani?

*i?iee Ay/aneaa Ieaenaiae?iae/,

ea??aiee a?aeae?eo aaaeii?iaeueii? iieieia??

Oe?a?inueeiai iaoeiai-aeine?aeiiai
?inoeoooo iieieia?? ? ?aae?ieia?? IIC Oe?a?ie

— aeieoi? iaaee/ieo iaoe, i?ioani?

Oau??a ?aoiai Eoe??ae/
i?ioani? eaoaae?e iieieia?? Ee?anueei?
iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe
?i.I.E.Ooieea IIC Oe?a?ie

I?ia?aeia onoaiiaa — Iaoe?iiaeueiee iaaee/iee oi?aa?neoao

?i. I. I. Aiaiiieueoey IIC Oe?a?ie, eaoaae?a
iieieia??, i. Ee?a

Caoeno aeena?oaoe?? a?aeaoaeaoueny «9» a?oaeiy 1998 ?. i 14 aiaeei?

ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.155.01 ?inoeoooy
aenia?eiaioaeueii? iaoieia??, iieieia?? ? ?aae?ia?ieia??

?i. ?.?.Eaaaoeueeiai IAI Oe?a?ie (252022, i. Ee?a, aoe.Aaneeuee?anueea,
45).

C aeena?oaoe??th iiaeia iciaeiieoenue a a?ae?ioaoe? ?AII?
?i.?.?.Eaaaoeueeiai IAI Oe?a?ie.

Aaoi?aoa?ao ?ic?neaiee » 4 eenoiiaaea1998.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee, aeieoi? iaaee/ieo iaoe

?.A.Aa?aiaiei.

Aeooaeuei?noue oaie. O??o?a?/iee iaoiae ? i?ia?aeiei o neeaae?
eiia?iiaaiiai oa eiiieaeniiai e?eoaaiiy ?aeo oeoiea [Aiiaea?ue A.A. c
ni?aaao., 1992; *i?iue A.A. c ni?aaao., 1996; *ennia A.?. c ni?aaao.,
1998]. O e?eoaaii? ?aeo oeoiea aeinyaiai? iaai? oni?oe, aea
aaciina?aaei? ?acoeueoaoe iacaaeia?euei?. *anoioa ?aii?o
i?ney-iia?aoe?eieo oneeaaeiaiue aeinyaa? 15,8% i?e aano?iaeoii??, i?e
i?ieneiaeuei?e ?acaeoe??- 17,7%, i?e iia?aoe?yo ia
ea?ae?iacioa-aaaeuei?e cii? oneeaaeiaiiy aeieeathoue o 22% — 29,9%
oai?eo, i?ney eiia?iiaaieo iia?aoe?e c?inoa? aaea?/? [Aoaoia N.A. c
ni?aaao.,1993; Caaa?iee E.A. c ni?aaao., 1993]. Eaoaeuei?noue o noa?-oeo
a?eiaeo a?oiao aeinyaa? 8,1% [Aeaaeaeia I.E. c ni?aaao., 1996], i?e
ea?ae?iacioaaaaeueiiio ?aeo 6,7% -16% [Aieiianueeee A.A. c ni?aaao.,
1996; ?noii?i TH.A., 1996].

Aeiaa? ?iee iaei ci?ith?oueny oaoiieia?y o??o?a?/iiai e?eoaai-iy,
aianoac?ieia?/ii? aeiiiiiae, aacia?a?aii aaeaioo?oueny aaeoa-??aeueia
oei?a aei iiaeo aioeaaeoa??aeueieo i?aia?ao?a. I?e oe?i-eiio aena?oeaii?
a no/ani?e iaoeia?e e?oa?aoo?? i?iaeaie Helico-bacter pylori o oai?eo ia
?ae oeoiea [Schlemper R.J. c ni?aaao., 1995; Hussell T. c ni?aaao.,
1996; Sito E. c ni?aaao., 1996] iaaeinoaoiuei aeeeaaeai? ieoaiiy aieeao
?ioaeoe?? ia e?eoaaiiy, i?oo?eaeoeeo, aeieeiaiiy oa ia?aa?a ?aii?o
caiaeueieo oneeaaeiaiue o??o?a?/iiai e?eoaaiiy ?aeo oeoiea.

Ca inoaii?e /an (10-20 ?ie?a) ciaioaiiy /anoioe oneeaaeiaiue oa
eaoaeueiino?, ye na?ae/aoue iaoeia? aeine?aeaeaiiy, ia iaea?aeaii
[Eoeaaoe I., 1991]. A oea a naith /a?ao iio?aao? aiae?co o?aaeeoe?eieo
i?aeoiae?a, ?o aeioe?eueiino? ? caeo/aiiy iiaeo aeaieo a?ae ?icaeoeo
noi?aeieo iaoe aeey iie?ioaiiy ?acoeueoao?a e?eoaaiiy oa aiae?co
i?e/ei aeieeiaiiy oneeaaeiaiue ? eaoaeueiino? oai?eo. Aeai? e?oa?aoo-?e
iathoue noia?a/iino? uiaei aecia/aiiy aaae oaeoi??a o aeiee-iaii? oa
ia?aa?ao i?neyiia?aoe?eieo caiaeueieo aioo??oiuei/a?aaieo oneeaaeiaiue
[Eden C.G., 1992; Aieiianueeee A.A. c ni?aaao., 1996; Eeeiaieia A.A. c
ni?aaao., 1996]. Aaaaeathoue, ui i?e/eiith eaoaeue-iino? ? aeniea
/anoioa caiaeueieo oneeaaeiaiue, yea aeinyaaa 80% [Aaenoyi A.I. c
ni?aaao., 1996]. A ?yae? aeiaaee?a aaciina?aaeiueith i?e/eiith nia?o?
oai?iai noa? ?ioieneeaoe?eiee neiae?ii [*aeaiei A.A., Eooooaa O.O.,
1990, Caao?nueea I.I., 1998]. Ae?aaiinoeea eiai aaco?oueny ia ee?i?/ieo
oa a?io?i?/ieo oaeoi?ao [Oaeueeia TH.E. c ni?aaao., 1993, Oai?eineee
A.A. c ni?aaao., 1995]. Aeai? i?i aaeaeaao-io ?aiith (aei ?icaeoeo
ee?i?/iiai i?iyaeaiiy) ae?aaiinoeeo oneeaae-iaiue, ui aaco?oueny ia
?a?no?aoe?? oaeaeeeo (10-1 n 10-6 n), oa iaaeoaeaeeeo (10-6 n 10
-12 c) [Oaoia?iiia I.E., 1980] i?i-oean?a o iaoeia?e e?oa?aoo??
i?aeoe/ii a?aenooi?. Aea/aiiy oaeaeeeo ? iaaeoaeaeeeo i?ioean?a ca
iaoiaeeeith oeueo?acaoeiai? niaeo?ineii?? ne?iaaoee e?ia? ia iaaoei
aeinoaoiueiai ?icaeoeo aeey oe?ieiai ee?i?/iiai aeei?enoaiiy.

Oaeei /eiii, ia’?eoeaia aecia/aiiy noaio i?aai?cio oai?iai ca
aeiiiiiaith oeueo?acaoeiai? niaeo?ineii?? ne?iaaoee e?ia?,
?io?-eiaaiino? neeciai? iaieiiee oeoieo Helicobacter pylori, c iaoith
?ic?iaee iioeiaeueieo i?aeoiae?a aei i?io?eaeoeee, ae?aaiinoeee ?
e?eoaaiiy ?aii?o i?neyiia?aoe?eieo oneeaaeiaiue, ? aeooaeueiith
iaoeiaith caaea/ath.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa aeeiiaia
ca?aeii c ieaiii iaoeiai-aeine?aeieo ?ia?o Oe?a?inueei? iaaee/ii?
noiiaoieia?/ii? aeaaeai??. Oeo? oaie 0198V000134.

Iaoa ?iaioe -iie?ioeoe aaciina?aaei? ?acoeueoaoe o??o?a?/iiai e?eoaaiiy
oao?eo ia ?ae oeoiea oeyoii i?io?eaeoe/ieo caoiae?a, ni?yiiaaieo ia
cieaeaiiy /anoioe aeieeiaiiy ?aii?o i?neyiia?a-oe?eieo oneeaaeiaiue oa
?o ae?aaiinoeee aei ee?i?/iiai i?iyao.

Caaaeaiiy aeine?aeaeaiiy:

1. I?iaanoe aiae?c aaciina?aaei?o ?acoeueoao?a o??o?a?/iiai e?eoaaiiy
?aeo oeoiea, c’ynoaaoe no?oeoo?o, i?e/eie aeieeiaiiy, ?acoeueoaoe
e?eoaaiiy ?aii?o i?neyiia?aoe?eieo aioo??oiuei/a?aaieo oneeaaeiaiue ia
iniia? ee?i?/ieo ? eaai?aoi?ieo oano?a.

2. Aea/eoe ca’ycie ?io?eiaaiino? aaeoa???th Ialicobacter pylori
neeciai? iaieiiee oeoiea oai?eo ia ?ae ?c aeieeiaiiyi ? ia?aa?-aii
i?neyiia?aoe?eieo oneeaaeiaiue, oieea e?eoaaiiy ?ioaeoe?? ia aeieeiaiiy
i?neyiia?aoe?eieo oneeaaeiaiue. ?ic?iaeoe iaoiaeeeo i?io?eaeoeee ?aii?o
caiaeueieo oneeaaeiaiue o??o?a?/iiai e?eoaaiiy ?aeo oeoiea
ia?aaeiia?aoe?eiei e?eoaaiiyi ?ioaeoe?? Ialicobacter pylori.

3. Aeine?aeeoe ci?ie a ne?iaaooe? e?ia? oai?iai i?ioyaii anueiai
e?eoaaiiy ca aeiiiiiaith iaoiaeo aeonoe/ii? niaeo?ineii??
(?a?no?a-oe??th oaeaeeino? iioe?aiiy oa eiao?oe??ioa iiaeeiaiiy
oeueo?acaoei-ai? oaee?, eiai aeiaiaeo ci?i) o ae?aiacii? /anoio 10 — 110
IAoe.

4. ?ic?iaeoe niin?a ae?aaiinoeee ?aii?o i?neyiia?aoe?eieo caiaeueieo
oneeaaeiaiue ca aeiiiiiaith ?a?no?aoe?? a ne?iaaooe? e?ia? oai?iai
eiao?oe??ioo iiaeeiaiiy oeueo?acaoeiai? oaee? oa aeiaiai? oaeaeeino?
eiai ci?ie.

5. ?ic?iaeoe ia iniia? i?iaaaeaieo aeine?aeaeaiue i?aeoe/i?
?aeiiaiaeaoe?? uiaei i?io?eaeoeee ? ae?aaiinoeee ?aii?o
i?neyiia?a-oe?eieo oneeaaeiaiue.

Iaoeiaa iiaecia. Oia?oa aena?oeaii ca’ycie ?aii?o caiaeueieo
aioo??oiuei/a?aaieo i?neyiia?aoe?eieo oneeaaeiaiue oa ?io?eiaaiino?
neeciai? iaieiiee oeoiea aaeoa???th Ialicobacter pylori. Io?eiaii
cieaeaiiy /anoioe i?neyiia?aoe?eieo oneeaaeiaiue i?e aeiiia?aoe?eii-io
e?eoaaii? oe??? ?ioaeoe??. Oia?oa a ee?i?/ieo oiiaao aea/aii aeanoeaino?
ne?iaaoee e?ia? oai?eo ia ?ae oeoiea ca aeiiiiiaith oeueo?acaoeiai?
niaeo?ineii??. Aeyaeaii caeaaei?noue aeiaiaeo ci?i eiao?oe??ioa
iiaeeiaiiy oeueo?acaoeo a ne?iaaooe? e?ia? oa noeeue-iino? oai?iai aei
aeieeiaiiy caiaeueieo oneeaaeiaiue.

I?aeoe/ia cia/aiiy ?acoeueoao?a. ?ic?iaeaia aoaeoeaia iaoi-aeeea
i?io?eaeoeee ?aii?o i?neyiia?aoe?eieo caiaeueieo aioo??oiuei-/a?aaieo
oneeaaeiaiue aeiiia?aoe?eiei e?eoaaiiyi ?io?eiaaieo Ieli-cobacter pylori
oai?eo. ?ic?iaeaiee i?eioeeiiai iiaee niin?a ae?aaiinoeee ?aii?o
i?neyiia?aoe?eieo oneeaaeiaiue ca aeiiiiiaith oeueo?acaoeiai?
niaeo?ineii?? aeicaiey? ae?aaiinooaaoe caiaeueia oneeaaeiaiiy ca aea?
aeiae aei ia?oeo ee?i?/ieo neiioii?a oa ?icaeo-eo iie?i?aaiii?
iaaeinoaoiino?. Iiaeeeaa onoiaiiy iniiaiiai iaaei-e?eo ?aeaia?ioii?? —
cai?ciaiiy ii a?aeiioaiith aei /ano aeieeiaiiy oneeaaeiaiiy.

Iniaenoee aianie caeiaoaa/a. Naiino?eii aeine?aeaeai? iniaee-aino?
ee?i?/iiai ia?aa?ao oai?iae oa oneeaaeiaiue e?eoaaiiy 447 oai?eo oa
i?iaaaeaii ii??aiyeueio oa?aeoa?enoeeo, caa?? iaoa??aeo aeey
a?noieia?/ieo, aaeoa??ieia?/ieo, aeonoe/ieo aeine?aeaeaiue. Naii-no?eii
i?iaaaeaia oeueo?acaoeiaa niaeo?ineii?y ne?iaaoee e?ia? oai?eo,
ocaaaeueiaiee aiae?c noeoiiino? ee?i?/ieo aeaieo oa ?acoeue-oao?a
eaai?aoi?ieo oano?a (caaaeueiee a?eie, aeueaoi?i, e?aaoei?i, caeeoeiaee
acio, na/iaeia, a?e??oa?i caaaeueiee, iai?yiee a?e??o-a?i, i?yiee
a?e??oa?i, eae?e, iao??e) ??cieo a?oi oai?eo. Aeai? noaoenoe/ii
ia?iaeai?, i?iaiae?ciaai?, ?ioa?i?aoiaai? iniaenoi aaoi?ii. Naiino?eii
noi?ioeueiaaia oi?ioea aeiaoiaeo.

Ai?iaaoe?y ?iaioe. Iniiai? iieiaeaiiy ?iaioe a?aeia?aaeai? o
ioae?eaoe?yo, iaaiai?thaaeenue ia iaoeiai-i?aeoe/i?e eiioa?aioe??
iieieia?a Oe?a?ie «Oeyoe ai?iaaaeaeaiiy iaea?eueo aoaeoeaieo iaoiae?a
iae?eo oa e?eoaaiiy iieioai?eo» 23-24 aa?aniy 1993 ?ieo i.Aeiiaoeuee; ia
iaoeia?e eiioa?aioe?? «Aeooaeuei? ieoaiiy oai?aoe/-ii? oa ee?i?/ii?
iaaeeoeeie ia no/aniiio ??ai?,» 20 o?aaiy 1996 ?ieo i.Iieoaaa 1996 ?.;
ia can?aeaii? eaoaae? Oe?a?inueei? iaaee/ii? noiiaoieia?/ii? aeaaeai??
3.02.98 ?ieo.

Ioae?eaoe?? ?acoeueoao?a aeine?aeaeaiiy. Ca iaoa??aeaie aeine?ae-aeaiue
iioae?eiaaii 7 iaoeiaeo i?aoeue, c yeeo o?e- ca iaeiiin?aiei aaoi?noaii
a iaoeiaeo aeo?iaeao, o?e — a iaoa??aeao eiioa?aioe?e oa iaeei iaoaio
ia aeiao?ae.

No?oeoo?a oa ianya aeena?oaoe??. Aeena?oaoe?y aeeeaaeaia ia 201
noi??ioe? ae?oeiaaiiai oaenoo, neeaaea?oueny c anooio, iaeyaeo
e?oa?a-oo?e, 5 ?icae?e?a, ye? i?noyoue aeeeaae iaoiae?a ? ?acoeueoao?a
aeine?ae-aeaiiy, aiae?co ? ocaaaeueiaiiy ?acoeueoao?a aeanieo
aeine?aeaeaiue, aeniiae?a, nieneo aeei?enoaii? e?oa?aoo?e (435
ia?oiaeaea?ae, c ieo oe?a?inueeith oa ?in?enueeith iiaaie — 329,
?iicaiieie — 106). ?iaioa ?ethno?iaaia 30 ?enoieaie, 30 oaaeeoeyie.

INIIAIEE CI?NO AeENA?OAOe??

?iaioa a?oioo?oueny ia ?acoeueoaoao ianoaaeaiiy ? e?eoaaiiy 447 oai?eo
ia ?ae oeoiea (T1-4N1-2M0) a o??o?a?/iiio a?aeae?eaii? Iieoaanueeiai
iaeaniiai ee?i?/iiai iieieia?/iiai aeeniaina?o. Aeine?aeeee ia?aa?a
i?neyiia?aoe?eiiai ia??iaeo o 402 oai?eo a caeaae-iino? a?ae noaio
oai?iai aei iia?aoe??, i?aeaioiaee aei ia?, ia’?io i?i-aaaeaiiai
o??o?a?/iiai e?eoaaiiy (ye naiino?eiiai, oae ? a neeaae? eiiieaeniiai),
ee?i?/ieo oaeoi??a (a?e oai?eo, aeao?oeeo iane o?ea, iayai?noue noiooi?o
caoai?thaaiue oa oneeaaeiaiue ?aeo oeoiea, o?eaa-e?noue iia?aoe??,
aaee/eia e?iaiao?aoe, a?aeiiaeaiiy e?iaiao?aoe, eaeeioeeoa?iee ?iaeaen
?ioieneeaoe??). O 45 oai?eo aea/eee ?acoeue-oaoe, aoaeoeai?noue oa
nai?/ani?noue ?aeaia?ioii?? ye iaoiaeo e?eo-aaiiy aioo??oiuei/a?aaieo
caiaeueieo i?neyiia?aoe?eieo oneeaaeiaiue. O 35 oai?eo i?iaaaeaiee
ii??aiyeueiee aiae?c iayaiino? aaeoa??? Ialicobacter pylori ia neecia?e
iaieiioe? oeoiea oa /anoioe aeiee-iaiiy caiaeueieo aioo??oiuei/a?aaieo
oneeaaeiaiue, a oiio /ene? o 26 oai?eo aea/eee aeoeai?noue
aetheice-6-oinoao -aeaa?ae?iaaiace (A-6-OAeA) ca iaoiaeii Iaoeana
[?.E?ee?, 1969]. Nooiiiue aaeoa??aeueii? caa?oaeiaiino? neeciai?
iaieiiee oeoiea Ielicobacter pylori aea/aee i?ae na?oeiaei i?e?ineiiii
Leitz Laborlux S [A?o?i E.E., ?naeia A.A., 1995] ia ia?ao?iiaeo c??cao
oiaueiith 10-12 iei, oa?aiaaieo aaiaoienee?iii oa aic?iii, ca A?ica.
Aeei?enoiaoaaee o?enaoe?th c?acea aethoa?iaei aeueaeaa?aeii oa ini??aith
eeneioith c caeeaeith a Aiii-812 [A.O?ee?, 1975] ? aeaioiaeyee
iai?aoiie? c??ce ia onoaoeoaaii? Iieoaanueeiai iaeaniiai
iaoieiaiaiaoii?/iiai ath?i. Aaeoa??ieia?/iei iaoiaeii a oiiaao
Iieoaanueei? iaeanii? NAN aea/eee iiaeeeaino? ?icaeoeo Ielicobacter
pylori a /a?aai?e ii?iaeiei? o 10 oai?eo i?ney ?aaeeeaeueieo iia?aoe?e
ia oeoieo.

O 35 oai?eo ia?aae iia?aoe??th i?iaaee i?io?eaeoe/ia e?eoaai-iy
oae?eiaaeoa??ico eiiieaenii i?aia?ao?a, yeee aeeth/aa oao?a-oeeee?i 0,5a
ii 4 i?eeiie ia aeiao, iao?ii?aeacie 0.5a ii 4 i?eeiie ia aeiao oa
a?eae?i ii 2 oaaeaoee 4 ?ace ia aeaiue i?ioyaii naie ae?a ia?aae
o??o?a?/iei e?eoaaiiyi.

O 187 c?aceao e?ia? 40 oai?eo aea/aii oaeaee?noue iioe?aiiy
oeueo?acaoeo oa eiao?oe??io iiaeeiaiiy iaoiaeii oeueo?acaoeiai?
niaeo?ineii?? [?oaeaiei I.I., Nia?ea/ A.N.,1992] ia /anoioao
aei?ii?ithaaiiy 10, 30, 50, 70, 90, 110 IAoe oa 5, 15, 25, 35, 45, 55
IAoe i?e iaaaeeeeo aiie?ooaeao, ia aeaio ?iioeuenieo onoaiiaeao c?a?aieo
ia eaoaae?? o?ceee Iieoaanueeiai aea?aeaaiiai iaaeaaia?/-iiai ?inoeoooo.

Iaoa??ae ii?aoeueiaaiee noaoenoe/ii ia IBM — 486 ca noaiaea?o-ieie
i?ia?aiieie i?iaeoeoaie ( Lotus 1.2.3.; Excel).

Iniiai? ?acoeueoaoe aeine?aeaeaiue oa ?oi? iaaiai?aiiy. C 402 oai?eo
/ieia?e?a aoei 238 (59,2%), ae?iie -164 (40,8%). 97% oai?eo ii/aee
e?eoaaiiy i?e iioe?aiino? iooeeie T1-4 N1-2 M0. Na?aaei?e a?e neeaa
59,13 7,3 ?ie?a. Oneeaaeiaiiy o??o?a?/iiai e?eoaaiiy aeieeee o 69
(17.2%) oai?eo, iiia?ei 33 (8.2%) oai?eo. Iio?aaa a ?aeaia?ioii??
aeieeea o 4,98 % oai?eo a?ae caaaeueii? e?eueeino? iia?aoe?e, oa
28,98%- a?ae caaaeueii? e?eueeino? oai?eo, o yeeo aeiee-ee oneeaaeiaiiy.
Eiioeiaaioe oai?eo ca aeaeaie iia?aoe?e iiae?eai? ia aeine?aeio a?oio
(o?, ui iaee oneeaaeiaiiy o??o?a?/iiai e?eoaaiiy) ? eiio?ieueio (oai??
ia iaee oneeaaeiaiiy e?eoaaiiy). Na?aae 255 oai?eo, ui ia?aianee
aeenoaeueio noaoioaeueio ?acaeoe?th oeoiea o 24 (9.4%) oai?eo
?icaeioeinue 35 oneeaaeiaiue. Caiaeuei? caeiyee 77%. Aeao?oeeo iane o?ea
o eiio?ieuei?e a?oi? +11.6 6.4 ea, o aeine?aei?e +9.5 2.2 ea.
Iaaeeeoeiaa iana o?ea noai?th? aeaye? oaoi?/i? ia?a-oeiaee a c?o/iiio
i?iaaaeaii? o??o?a?/iiai ao?o/aiiy. Noiooi? caoai?thaaiiy o?aaeaee 172
(74.46%) oai?eo o eiio?ieuei?e a?oi? oa 19 (79.2%) o aeine?aei?e, ui ia
a?aeiia?aea? aeaiei e?oa?aoo?e, aea iaai-aeyoueny iaio? cia/aiiy
[Aeaauaeia I.?., 1996]. No?oeoo?a noi?ia?ae-ieo caoai?thaaiue
a?aeiia?aea? aeaiei e?oa?aoo?e. A no?oeoo?? ia?aaa-aeaee oai?iae, ui
cia/ii iia??oothoue aaiiaeeiai?eo (?oai?/ia oai-?iaa na?oey 84.3% ?
78.3%), a c iath ? i?noeaao o?io?eo oeaiei i?aa-i?cio. Oai?iae
aano?iaioa?ieia?/iiai i?io?eth i?aeoe/ii ia ae?aaiinooaaeenue /a?ac
iai?oanoi? ee?i?/i? i?iyaeaiiy iioe?aii? iooeeie oeoiea. Oneeaaeiaiiy
?aeo oeoiea o aeine?aei?e a?oi? neeaee 12.6%, o eiio?ieuei?e — 22.9%,
ia?aaaaeii ca ?aooiie aiai?? (a?aeiia?aeii 33% ? 67.9%).
Aaiio?ainooc?yie, i?e a?aenooiino? aeoea-ii? e?oaioa/?, aiai?th
aaeaaaeiny ei?aeooaaoe o?eueee o /anoeie oai?eo. Iiai?noth iieacieee
(e?euee?noue a?eo?ioeeo?a, aaiiaeia?i, aaiaoie?eo) ii?iae?coaaeeny
o?eueee i?ney o??o?a?/iiai e?eoaaiiy. Oneeaaeiaiiy oai?iae ia iaee
aaaiiiai cia/aiiy o aeieeiaii? oneeaaeiaiue e?eoaaiiy. Aiaeia?/i?
niinoa?aaeaiiy ciaoiaeeii a iaoeia?e e?oa?aoo?? [Aiiaea?ue A.A. c
ni?aaao., 1992]. I?ae iaiia a?oiaie oai?eo ??cieoe? a o?eaaeino?
iia?aoe?? ia aoei, aiia neeaaea? 149 6 oaeeei. Aaee/eia e?iaiao?aoe a
eiio?ieuei?e a?oi? neeaaeaea a na?aaeiueiio 456 21 ie, a aeine?aei?e
575 42 ie. Anoaiiaeaii, ui a no?oeoo?? oneeaaeiaiue i?ney aeenoaeueii?
noaoioaeueii? ?acaeoe?? oeoiea ia?aaaaeaee ia?eoii?o (11.4%), aino?ee
i?neyiia?aoe?eiee iaie?aaoeo (11.4%), eeoeiaa iai?io?aei?noue (11.4%),
iiaaiii?y (11.4%). O 9 oai?eo oneeaaeiaiiy iio?aaoaaei ?aeaia?ioii??.
Iiia?ei a?ae oneeaaeiaiue 8 oai?eo (3.1%). I?e ii??aiyeueiiio aiae?c?
iaoiaeee iaeeaaeaiiy oeoieiaieeoeiaeo aianoiiic?a (ca
Aioiaenoa?ii-O?inoa?a?ii, A?oaanueeei), iiaeiaaeaiino? iaoe? eeo-ee,
i?inoi?iaiai ?? ?ici?uaiiy, noaoenoe/ii aeinoia??ieo a?aei?i a ieai?
aaciina?aaei?o ?acoeueoao?a, ia io?eiaii.

Iaiao?aei?noue a eiia?iiaai?e aeenoaeuei?e ?acaeoe?? aeieeea o 30
oai?eo. O 20 e?eoaaiiy i?ieoei aac oneeaaeiaiue (eiio?ieueia a?oia), o
10 (33.3%)- aeine?aeia a?oia- aeieeei 13 oneeaaeiaiue. Na?aae ieo
caiaeaiiy eaaai?a o 3 oai?eo, iaie?aaiae?ic- o 2 oai?eo, ia?eoii?o o 2,
iaaeinoaoi?noue oianoieeoeiaiai aianoiiico o 3, oiene/ia aioeaoaeiiao?y-
o 1, aoii?y eoene oeoiea- o 1, ?cieueiaaia iaaii?iiy ?aie- o 1 oai?iai.
Iiia?ei a?ae oneeaaeiaiue 5 (16.7%) oai?eo. Ca iaaeeeoeiaith ianith,
no?oeoo?ith ca a?eii, oneeaaeiai-iyie oai?iae, a?oie ia a?ae??ciyeenue.
Na?aae i?aai?a, ui aoiaeeee aei eiiieaeno i?aai?a, yeee aeaeaeyany, 40%
caeiaa o?aaiaio oianoi? eeoee,- naeac?iea, aeia/iee i?oo?, o?aaiaio
i?aeoeoieiai? caeice, aioo??oi? ae?ii/? noaoaa? i?aaie aeaeaeyeenue c
iaeeiaeiaith /anoioith (15%). Uiaei iaoiaeeee iaeeaaeaiiy aianoiiic?a oa
aeei?enoaiiy iaoe? oiiei? eeoee, oi aieea ?o ia aaciina?aaei?
?acoeueoaoe aeyaeany ianooo?aei.

Aano?iaeoii?y aeeiiaia 67 oai?ei, na?aae ieo o 9 (13,4%) aeieeei 13
oneeaaeiaiue. Iiia?ei 6 (8.96%) oai?eo. Na?aaei?e a?e oai?eo aac
oneeaaeiaiue noaiiaea 55.91.3 ?ie?a (eiio?ieueia a?oia), c
oneeaaeiaiiyie — 60.66.4 ?ieo. A aeine?aei?e a?oi? noiooi? oai?i-ae
o?aaeaee 56.9% oai?eo, a eiio?ieuei?e-33.3%, ia?aaaaeii ca ?aooiie
?oai?/ii? oai?iae na?oey (87.9% ? 100% a?aeiia?aeii). Oeei aeaiei
a?aeiia?aea? cia/aiiy iaaeeeoeiai? iane o?ea 11.62.3ea ? 14.87
a?aeiia?aeii. Ia’?i e?iaiao?aoe i?ae /an iia?aoe?? i?aeoe/ii ia
a?ae??ciyany (50349 oa 57278 ie). O?eaae?noue iia?aoe?? a eiio?ieue-i?e
a?oi? — 18814, o aeine?aei?e 21419 oaeeei. Nooo?ai? ??cieoe? a
aaciina?aaei?o ?acoeueoaoao a?ae aeei?enoaiiy aianoiiic?a ca
A?ey?iae/ai- Oae?iiaei, ca Aiiaea?ai oa ca iaoiaeeeith ee?i?ee [Oaeaoei
I.A., 1990] anoaiiaeoe ia aaeaeiny, ui a?aei?/aii a iaoeia?e e?oa?aoo??
[Aieiianueeee A.A. c ni?aaao., 1996 ].

Eiia?iiaaia aano?iaeoii?y i?iaaaeaia 30 oai?ei. Iaee i?noea 26
oneeaaeiaiue o 16 (53.3%) oai?eo (aeine?aeia a?oia). Na?aaei?e a?e
oai?eo eiio?ieueii? a?oie noaiiaea 56.25.2 ?ie?a, aeine?aeii?- 62.16.5.
Noiooi? oai?iae a eiio?ieuei?e a?oi? o?aaeaee 64.2% oai?eo, o
aeine?aei?e -100%, ia?aaaaeii ca ?aooiie ?oai?/ii? oai?i-ae na?oey
(a?aeiia?aeii 88.9% ? 87.5%). Oneeaaeiaiiy ?aeo oeoiea aeieeee
a?aeiia?aeii 14.3% ? 43.75%. ??cieoe? a iaaeeeoeia?e ian? a?oi oai?eo ia
aoei. O?eaae?noue iia?aoe?? o oai?eo eiio?ieueii? a?oie neeaea 17132
oaeeeie, aeine?aeii? — 253 67 oaeeei. Aei eiiieaeno i?aai?a, ui
aeaeaeyany, o 47.4%(18 oai?eo) aeiaaee?a aeeth/eee naeac?ieo, ii 13.2%(5
oai?eo)- o?aaiaio oianoi? eeoee oa i?aeoeoi-eiai? caeice, 10.5%(4)
o?aaiaio no?aaioiaeo, o 7.9%(3) oai?eo- aeeiiaia ?icoe?aia
e?ioaaeaiaeoii?y, oa ii 2.6%(1)- o?aaiaio ia/?iee, aeia/iee i?oo?,
y?/ieee. Aeaeaeaiiy o?ueio oa a?eueoa i?aai?a aaaaeaee iaaeioe?eueiei. A
no?oeoo?? oneeaaeiaiue 8% caeiyea iiaaiii?y, 11% aanoean /a?aaii?
ii?iaeieie, 4% eeoeiaa iai?io?ae-i?noue, 26% i?neyiia?aoe?eiee
iaie?aaoeo, 8% ii?eoe? ii?iaeienoeo i?aai?a, 8% iaaii?iiy ?aie, 11%
ia?eoii?o, 4% e?iaioa/a ?c ?aie, 12% na?oeaainoaeeiia iaaeinoaoi?noue,
4% o?iiaiaiaie?y eaaaiaai? a?oa???, 4% o?iiaioeaa?o iiaa?oiaaeo noaeei.
Caiaeuei? oneeaaeiaiiy neeaee 80%.

I?ieneiaeueia ?acaeoe?y oeoiea oa iia?aoe?? ia eoen? oeoiea. I?iaaaeaii
15 i?ieneiaeueieo ?acaeoe?e, o 6 (40%) oai?eo aeieeee oneeaaeiaiiy
e?eoaaiiy. Iiia?ei 2 (13.3%). Acaaae? oeae eiioeiaaio oai?eo
a?ae??ciyany cia/iith iaaeeeoeiaith ianith (+15.36.4 ea), o?eaae?noth
iia?aoe?? (25217 oa), oa e?iaiao?aoith i?ae /an iia?aoe?? (75153 ie).
?aaeeeaeuei? iia?aoe?? ia eoen? oeoiea aeeiiaii 5 oai?ei.

*anoioa oneeaaeiaiue e?eoaaiiy oa eaoaeuei?noue a?aeiia?aeathoue aeaiei
e?oa?aoo?e. A no?oeoo?? oneeaaeiaiue e?eoaaiiy ia?aaaaeathoue
oneeaaeiaiiy caiaeueiiai oa?aeoa?o ( aei 80%). Noeoii?noue oai?eo c
aeine?aeieo oa eiio?ieueieo a?oi a iaaeao aeaeo iia?aoeaiiai ao?o-/aiiy
aeineoue iaeii??aeia ca a?eii, noiooi?ie oai?iaaie, oneeaae-iaiiyie ?aeo
oeoiea, oaoi?eith ? iaoiaeeeith i?iaaaeaiiy iia?aoe??. Cia/iiai aieeao
ia aaciina?aaei? ?acoeueoaoe e?eoaaiiy oe? oaeoi?e ia iaee a iaaeao
iia?aoe?e iaeiiai ia’?io. Cia/aiiy ?o c?inoaei c? ca?eueoaiiyi ia’?io
o??o?a?/iiai ao?o/aiiy, ui aoei iaiao?aeii i?e a?eueo?e iioe?aiino?
iieieia?/iiai i?ioeano. I?e c?inoaii? o?aaia-oe/iino? iia?aoe??, yeo
ia’?eoeaii iiaeia ii??aithaaoe ca o?eaae?n-oth iia?aoe?? oa aaee/eiith
e?iaiao?aoe, c?inoa? /anoioa oneeaaeiaiue ? eaoaeuei?noue. Iathoue
cia/aiiy eiiiainaoi?i? iiaeeeaino? i?aai?c-io oai?iai, ui ia?ai?n
iia?aoe?th ? ia?eic. Cia/aiiy iieaciee?a eaeeioeeoa?ii? ?ioieneeaoe?? a
ae?aaiinoeoe? caiaeueieo oneeaaeiaiue ia iaoiio iaoa??ae? ca?aathoueny c
aeaieie e?oa?aoo?e, aea ia aoei ?ioi?iaoeaia.

C aeeeaaeaiiai aeieea? aeniiaie, ui aaciina?aaei? ?acoeueoaoe e?eoaaiiy
?aeo oeoiea caeaaeaoue a?ae aeo?aeiiai ??aiy ?ioieneeaoe?e-iiai
neiae?iio, yeee ciaoiaeeoueny a o?niiio ni?aa?aeiioaii? c iioe-?ai?noth
iieieia?/iiai i?ioeano, eiiiainaoi?ieie iiaeeeainoyie i?aai?a ? nenoai
i?aai?cio oai?iai oa aaee/eiith yo?iaaiieo aieea?a, ui iiaeooue
ca?eueooaaoe ?ioieneeaoe?th,- ia?aaeiia?aoe?eii? i?aeaioiaee
iia?aoeaiiai ao?o/aiiy oa ia?eico. Aeei?enoai? caaaeue-iii?eeiyo?
ee?i?/i?, a?io?i?/i? oaeoi?e iaaeinoaoiuei ?ioi?iaoeai? a a?aeia?aaeaii?
ci?i ??aiy ?ioieneeaoe??, oiio ui ?ioieneeaoe?eiee neiae?ii
neeaaea?oueny c? cia/ii? e?eueeino? eaiie.

Aeine?aeaeaii oieea oae?eiaaeoa??ico ia aeieeiaiiy ? ia?aa?a
aioo??oiuei/a?aaieo caiaeueieo oneeaaeiaiue o??o?a?/iiai e?eoaaiiy, ye
neeaaeiai? /anoeie ?ioieneeaoe?eiiai neiae?iio. 35 oai?ei ia ?ae oeoiea
(?aiaeii?ciaaia aea??ea), o ieai? ia?aaeiia?aoe?eii? i?aeaioiaee,
i?iaaaeaii naieaeiaiaee eo?n e?eoaaiiy Helicobacter pilori eiiieaenii
i?aia?ao?a- aeine?aeia a?oia. Ca eiio?ieueio a?oio i?eeiyee 138 oai?eo,
ui e?eoaaeenue o o??o?a?/iiio a?aeae?eaii? ca oie aea i?ii?aeie /ano aac
ia?aaeiia?aoe?eiiai e?eoaaiiy oae?eiaae-oa??ico. Eo?n e?eoaaiiy
oae?eiaaeoa??ico ia iiaeiaaeea o?eaae?noue ia?aaeiia?aoe?eiiai ia??iaeo.

Na?aaei?e a?e oai?eo aeine?aeii? a?oie neeaaeaa 57,9 10,8 ?ie?a i?e
58.9 9.5- o eiio?ieuei?e a?oi?. Iaaeeeoie iane o?ea oai?eo a?aeiia?aeii
+3,1 2,3 ea oa +8.2 1.9 ea. Noiooi? caoai?thaaiiy iaee i?noea o 26
(74.3 %) oai?eo aeine?aeii? a?oie. A eiio?ieuei?e a?oi? iieaciee neeaa
82.6%. Nooo?ai? ??cieoe? i?ae a?oiaie ii no?oeoo?? oa e?eueeino?
noiooi?o caoai?thaaiue anoaiiaeoe ia aaeaei-ny. Aei iiiaioo iia?aoe??
ca noiooi?ie caoai?thaaiiyie oai?? aoee a noai? eiiiainaoe??.
Oneeaaeiaiiy oai?iae a aeine?aei?e a?oi? aoei o 6(17.1%) oai?eo, a
eiio?ieuei?e- o 18 (13.0%) oai?eo. A no?oeoo?? oneeaaeiaiue ia?aaaaeaea
aiai?y. O an?o oai?eo iaa i?noea ??ciiai nooiaith ?ioaineaiino?
aeeniaioe/iee oa aieueiaee neiae?iie, iia’ycai? c iniiaiei
caoai?thaaiiyi.

14 (40.0%) oai?eo i?ney e?eoaaiiy oae?eiaaeoa??ico a?ae/oee cieaeaiiy
?ioaineaiino? aieueiaiai oa aeeniaioe/iiai neiae?ii?a. O?eaae?noue
o??o?a?/iiai ao?o/aiiy o eiio?ieuei?e a?oi? neeaea 144 28 oa., o
aeine?aei?e -169 7 oaeeei aac nooo?aeo a?aei?iiinoae a ia’?i?
ao?o/aiiy. E?iaiao?aoa neeaea a?aeiia?aeii 493 ± 207ie ? 552 ± 62. A
eiio?ieuei?e a?oi? ae?aaiinoiaaii oneeaaeiaiiy e?eoaaiiy caiaeueiiai
oa?aeoa?o a /a?aai?e ii?iaeiei? o 23 (16.7%) oai?eo. A aeine?aei?e
a?oi? oneeaaeiaiiy e?eoaaiiy ae?aaiinoiaaii o?eueee o 2 (5.7%) oai?eo —
iaie?aaoeo ? a?aecia/aeinue aeineoue eaaeei ia?aa?aii. ?acoeueoao ii
/anoio? aeieeiaiiy oneeaaeiaiue aaea?/? iaioee, i?ae a eiio?ieuei?e
a?oi?.

Aea/eee iayai?noue oa e?euee?noue aaeoa??e ia neecia?e iaieiioe?
oeoie?a, aeaeaeaieo i?ae /an ?aaeeeaeueieo iia?aoe?e. A?eueo?noue
aaeoa-??e iaee oeiiao aeey oae?eiaaeoa?a S-iiae?aio oi?io. I?e
ia?ai?-uaii? i?e?iaaeioii o oiauei? c??co oeaieie i?inoaaeoaaee
oaiaai-oe?eii i???ioiaai? aaeoa??? oa i?ae?aooaaee ?o e?euee?noue.
Ia?aaaaeia a?eueo?noue aaeoa??e ?icoaoiaai? a oa?? neeco, aea aoee ?
eiioaeooth-/? c ee?oeiaie ai?oae?th. Iniaeeai ae?acii aeyaey?oueny oea
a?ey ee?oei c iciaeaie aeano?oeoe??. Aeey ?aeaioeo?eaoe?? aaeoa??? a
c??cao oeaiei aeei?enoiaoaaee a?noio?i?/i? ?aaeoe?? ia ieneaeace a
e??i-noaoieo c??cao. ?aaeoe?y ia aetheico — 6 — aeaa?ae?iaaiaco aeineoue
niaoeeo?/ia aeey Helicobacter pylor?. Oaaeeoey 1.

?io?eiaai?noue aaeoa???th Helicobacter pilori neeciai? iaieiiee oeoieo o
oai?eo ia ?ae oeoiea.

Oai??, ui iaee caiaeuei? oneeaaeiaiiy (n=20)Oai??, ui caiaeueieo
oneeaaeiaiue e?eoaaiiy ia iaee (n=15)?E?euee?noue i?e?iaieo o?e a
iie? ci?o56 1112 7 0.05 Oai?? (n=20) c caiaeueieie
aioo??oiuei/a?aaieie i?neyiia?a-oe?eieie oneeaaeiaiiyie iaee na?aaei?e
(20-50 i?e?iaieo o?e o iie? ci?o) oa aenieee (50 ? a?eueoa) ??aaiue
caa?oaeiaiino? oae?eiaaeoa?ii. Oai??, i?neyiia?aoe?eiee ia??iae o yeeo
ia?aa?aaa aac oneeaaeiaiue (n=15), a?ae??ciyeenue iecueeei ( aei 20
aaeoa??e o iie? ci?o) ??aiai ?io?eiaaiino? neeciai? iaieiiee oeoieo.

?ioeineai?noue caa?oaeiaiino? neeciai? iaieiiee Helicobacter pilori
ca?aa?oueny c ae?aaeai?noth caiaeueieo ci?i neeciai? iaieiiee, ye
iieacaii ?ai?oa a e?oa?aoo?? [A?o?i E.E., ?naeia A.A., 1995].

Iayai?noue oa aeeoo?ae?yeuei?noue ia neecia?e iaieiioe? oeoiea
oae?eiaaeoa?a iiaea noaiiaeoe iaeio c neeaaeiaeo /anoei oieneeico o
oai?iai ia ?ae oeoiea, ui a?ae?a?a? cia/io ?ieue o caa?aaeaii? /e ao?ao?
??aiiaaae i?ae eiiiainaoi?ieie iiaeeeainoyie i?aai?cio ? eiiieaenii
aeueoa?oth/eo oaeoi??a -ii/aoeiaee ??aaiue aiaeioiene-eico oa iia’ycaiee
c iia?aoe??th ? ia?eicii. Iiaeeeai, ui ?icaeoie oae?eiaaeoa?o ia
neecia?e iaieiioe? oeoiea a?aeiia?aea? noaiia? ?ioi?oaoo i?aai?cio.
I?aeoaa?aeaeaiiy aaciina?aaeiuei? o/ano? aaeoa??? a ?icaeoeo caiaeueiiai
i?ioeano a /a?aai?e ii?iaeiei? io?eiaoe ia aaeaeiny.

Ii??aiyeueia ioe?iea oai?eo, ui iaee caiaeueia oneeaaeiaiiy
o??o?a?/iiai e?eoaaiiy ?aeo oeoiea a /a?aai?e ii?iaeiei? iieaca-ei, ui
nooo?ai? ??cieoe? o no?oeoo?? ca a?eii, noaooth, iaaeeeoeii iane o?ea,
oneeaaeiaiyie ?aeo oeoiea iaia? a ?aieao iaeiiai aeaeo iia?aoe?e. Cia/io
aaao ia? o?aaiaoe/i?noue ia?oi? iia?aoe??, ui i?iyaey?oueny o?eaae?noth
iia?aoe?? oa e?iaiao?aoith. Oae, o a?oi? oai?eo i?ney ?aeaia?ioii??, ui
cae?i/eeanue aeaeoaeaiiyi (n=13), o?eaae?noue ia?aeiii? iia?aoe??
noaiiaeea 15938 oaeeei, a a?oi?, aea ?aeaia?ioii?y cae?i/eeanue
iaaaea/ath (n=32), 22337 oaeeeie. Aiaeia?/ii e?iaiao?aoa neeaea 45578 ?
775179ie.

?aeaia?ioii?y i?e caiaeueieo aioo??oiuei/a?aaieo oneeaaeiai-iyo ?
o??o?a?/iei iaoiaeii ai?ioueae c ?ioieneeaoe??th. Oae, na?aae i?e/ei, ui
iio?aaoaaee iiaoi?iiai ao?o/aiiy o 32%- aeiaaee?a aoea eeoeiaa
iai?io?aei?noue, o 13%- iaaeinoaoi?noue aianoiiico, o 16% — aanoean
/a?aaii? ii?iaeieie, 13%- aino?ee iaie?aaoeo, 2%- aaaioa?aoe?y, 22%-
ia?eoii?o, 2%- aino?ee oieaoeeno?o. Na?aae iia?aoeaieo i?eeii?a i?e 45
?aeaia?ioii?yo o 15,1% oai?eo aoei onoiaiiy eeoeiai? iai?io?aeiino?, o
1,2%- ?acaeoe?y iaaeeoo?caeaoii? eeoee, o 27,9%- aeiaeaoeiaa
ae?aioaaiiy, o 1,2%- ?acaeoe?y i?aeoeoieiai? caeice, o 2,3%- ?icoei
ii?iaeieie aanoeano, o 1,2% -coieiea e?iaioa/?, o 12,1%- ooeaaiiy
ia?oi?aoe?? eeoee /e aianoiiico, o 1,2%- iaeeaaeaiiy iao?aeiiai
aianoiiico, o 25%- naiaoe?y /a?aaii? ii?iaeieie, o 1,2%- ?a?acaeoe?y
iaaeeoo?caeaoii? eoene, o 8,1%- ooaaae oiiei? eeoee, o 2,3%- iaeeaaeaiiy
eeoeiai? noiie, o 1,2%- ooeaaiiy aaaioa?aoe??. Aoaeoeai?noue iaoiaeo
iia??-oo?oueny o oai?eo c a?eueoei aeo?aeiei ??aiai ?ioieneeaoe?eiiai
neiae?iio (ii iioe?aiino? iooeeie oa o?aaiaoe/iino? ao?o/aiiy). Oae,
na?aae oai?eo c iiaoi?iei ao?o/aiyi i?ney aeenoaeueii? noaoi-oaeueii?
?acaeoe?? iiia?ei 11 (55%), i?ney eiia?iiaaii? aeenoaeueii? ?acaeoe?? 5
(100%), aano?iaeoii??- 5 (62.5%), eiia?iiaaii? aano?i-aeoii??- 4 (100%),
i?ieneiaeueii? ?acaeoe??- 2 (66.7%), ?aaeeeaeueii? iia?aoe?? ia eoen?
oeoieo- 5 (100%). Caaaeueia eaoaeueinoue i?ney ?aeaia?ioii?? neeaea
71.1%.

I?e ?ao?iniaeoeaiiio aiae?c? aeyaeaii, ui a?ae ii/aoeo neii-oii?a
iaaeaaiiieo//y aeo i?eeiyooy ??oaiiy i?i ?aeaia?ioii?th i?ieoei 3.8 2.8
aiaeeie o oai?eo, ui aeaeoaeaee, oa 50.1 28.6 aiaeeie o oai?eo, ui
iiia?ee. Cia/iee /an ia?aae ?aeaia?ioii??th iiynith?oueny neeaaeiinoyie
ae?aaiinoeee oneeaaeiaiiy ? aeei?enoi-aoaaany aeey aeiianoaaeaiiy,
eiina?aaoeaiiai e?eoaaiiy, i?eeiyooy ??oaiiy i?i ?aeaia?ioii?th. Oai??,
ui e?eoaaeenue eiina?aaoeaii c caaeia?eueiei ?acoeueoaoii, ia iaee
nooo?aeo oa?aeoa?ieo ?aii?o iciae oneeaaeiaiiy. Ee?i?/i? (nea?ae ia aie?
a /a?aai?e ii?iaeiei?, iciaee iiae?aciaiiy /a?aaeie, i?aeaeuaiiy
oaiia?aoo?e o?ea aei 38-390 N, cieaeaiiy a?oa??aeueiiai oeneo i?e
iayaiino? oao?ea?ae?? — a?ae 100 oaea??a ca oaeeeio, ?icaeoie eieaina,
iayai?noue aiith a ae?aia-aeao) oa eaai?aoi?i? (a?io?i?/i? iieacieee,
noai ia?eoa??eii? e?ia?, eaeeioeeoa?i? ?iaeaene ?ioieneeaoe??) oaeoi?e
?aaaoaaee o?eueee ia iayai?noue iioe?aiiai caiaeueiiai oneeaaeiaiiy,- ia
aoai? iaa?i-iaaeaeaiiy i?iaeoeo?a ia?aeiiiai aoaeoo oa aeaeiiiainaoe??
?aaoey-oi?ieo nenoai oa aooiaa?an??. Noaae?y i?eoiaaiiai aiaeioieneeico
[*aeaiei A.A., Eooooaa O.O., 1990] ieie i?aeoe/ii ia ae?aaiinoo-aaeanue.
Iaee ni?aao c iie?i?aaiiith iaaeinoaoi?noth, oiio iiaoi?ia iia?aoe?y
aoea iaaecae/aeii aaaeeith aeey i?aai?cio oai?iai aenia-aeaiiai iniiaiei
i?ioeanii, ia?aianaiith iia?aoe??th oa cia/iei ??aiai aiaeioieneeico.

Aea/aiiy ieeao eiioi?iaoe?eieo ci?i iieaeoe i?aai?cio ia noai oai?iai,
?acoeueoaoe e?eoaaiiy (ye iaaeeeaiaioiciiai, oae ? o??o?a?/iiai),
ia?aa?a oai?iae i?iaiaeeee ca aeiiiiiaith iaoiaeo oeueo?acaoeiai?
niaeo?ineii?? oeyoii aei??thaaiiy eiao?oe??ioa iiaeeiaiiy, oaeaeeino?
iioe?aiiy caoeiai? oaee? a ne?iaaooe? e?ia? iieieia?/ieo oai?eo a
oe?ieiio ae?aiacii? /anoio. Aeei?enoaiiy ?iioeueniiai oeueo?acaoeiaiai
iaoiaeo ci?iii? a?aenoai? c aaeaeaaoiei iaoaiaoe/iei caaacia/aiiyi
aeicaiey? ae??oeoe oeth i?iaeaio.

Iaoiaeeea canoiniaaia na?aae a?oie c 40 oai?eo, c yeeo iaeoaeaee aac
oneeaaeiaiue 23 oai?eo oa 17 — c oneeaaeiaiiyie, o oiio /ene? iiia?ee
a?ae oneeaaeiaiue 3 oai?eo.

Oaeaee?noue iioe?aiiy oeueo?acaoeo, aaaeeeaee ia?aiao?
a?ae?i-aeeiai?/ii? oai??? ??aeei, aeyaeany, ye iieacaee iao?
aeine?aeaeaiiy iaei /ooeeaei aei ci?i noaio i?aai?cio ii??aiyii c
eiao?oe??ioii iiaeeiaiiy ? ci?ithaaanue o iaaeao a?ae 1532.0 aei 1572.0
i/n, ui a?aeiia?aea? aeaiei e?oa?aoo?e [Ia?neaieiia E.N., Aeaieaeia
A.I., 1982].

Aei??thaaiiy eiao?oe??ioa iiaeeiaiiy oeueo?acaoeo ne?iaaoee e?ia? ia
??cieo /anoioao aeicaieeei aeyaeoe cia/io /ooeea?noue oeueiai ia?aiao?a
aei ci?i noaio i?aai?cio. Caeaaei?noue eiao?oe??ioa iiaeeiaiiy
oeueo?acaoeo ia aeine?aeaeoaaieo /anoioao a?ae a?io?i?/ieo iieaciee?a
(caaaeueiee a?eie, aeueaoi?i, e?aaoei?i, caeeoeiaee acio, na/iaeia,
a?e??oa?i caaaeueiee, iai?yiee a?e??oa?i, i?yiee a?e??o-a?i, eae?e,
iao??e), a oaeiae a?ae noaoaai?, a?oiiai? i?eiaeaaeiino? oa
?acon-oaeoi?a oai?eo anoaiiaeoe ia aaeaeinue. Eiao?oe??io ei?a-eyoe??
iaaeeaea?oueny aei 0. I?e ci?i? oaiia?aoo?e noano?aoo, ui
aei-ne?aeaeoaaany eiao?oe??io iiaeeiaiiy cia/ii ci?ithaaany. Ei?aeyoe?y
oaiia?aoo?ieo ci?i eiao?oe??ioa iiaeeiaiiy oeueo?acaoeo neeaea
+0.990.01, oiio aeine?aeaeaiiy i?iaiaeeee i?e noae?e oaiia?aoo?? 370N.

Oaaeeoey 2. Eiao?oe??io iiaeeiaiiy oeueo?acaoea a ne?iaaooe?
e?ia? ia /anoioao 15, 25, 30, 50 IAoe a ia?aaeiia?aoe?eiee ia??iae.

A?oie*anoioa aei?ii?ithaaiiyoai?eo15 IAoe25 IAoe30 IAoe50 IAoeOai??, ui
ia iaee oneeaaeiaiue e?eoaaiiy 9624911684127815Oai??, e?eoaaiiy yeeo
oneeaaeieeinue 9118931183148013 I?e P0,05.

Aiae?ciaaii ia?aa?a i?neyiia?aoe?eiiai ia??iaeo o oai?eo ca aeaieie
ee?i?/ieo niinoa?aaeaiue, ye? ca?a?no?iaai? a ?noi??? oai?i-ae, oa ca
aeiaeaoeiaeie iaoiaeaie ianoaaeaiiy, iieacieeii eaeeioee-oa?ii?
?ioieneeaoe?? (a o./. ca Eaeueo-Eae?oii) oa eiao?oe??ioii iiaeeiaiiy
oeueo?acaoeiai? oaee? ia /anoioao 10, 30,50, 70,90 IAoe oa 5, 15, 25,
35, 45, 55 IAoe. I?e aiae?c? a?aeeny aei oaaae o?eueee aeai?, io?eiai?
ia /anoioao 30,50 IAoe ? 15,25 IAoe.

Nooo?ai? ??cieoe? i?ae cia/aiiyie eiao?oe??ioa iiaeeiaiiy o a?oi oai?eo
a ia?aaeiia?aoe?eiiio ia??iae? anoaiiaeoe ia aaeaeinue.

I?ney ia?aianaii? iia?aoe?? oa ia?eico ianoa? cia/ia cieaeai-iy
eiao?oe??ioa iiaeeiaiiy oeueo?acaoeo, ? o?eueee c 3-4 aeiae cia/ai-iy
iieacieea i?aeaeuo?oueny. Iiaeeeaee aa??aio c i?aeaeuaiiyi eia-o?oe??ioa
iiaeeiaiiy a?ae?aco i?ney iia?aoe??, aea cieaeaiiy cono??-/a?oueny
/ano?oa a iaio a?oiao.

A a?oi? oai?eo, ui ia?aianee e?eoaaiiy aac oneeaaeiaiue, iaea i?noea
neeueia iaaaoeaia i?yia ei?aeyoe?y cia/aiue eiao?oe??ioa iiaee-iaiiy
oeueo?acaoeo a ne?iaaooe? e?ia? aei iia?aoe?? oa ia 3 aeiao i?ney
iia?aoe??, aeniea iiceoeaia i?yia ei?aeyoe?y cia/aiue eiao?oe??ioa
iiaeeiaiiy ia 3 aeiao i?neyiia?aoe?eiiai ia??iaeo oa i?e aeienoe? ?c
noaoe?iia?o. A a?oi? oai?eo c oneeaaeiaiiyie e?eoaaiiy caiaeueiiai
oa?aeoa?o i?ae eiao?oe??ioii iiaeeiaiiy oeueo?acaoeo aei iia?aoe?? ? a
ia?o? o?e aeiae i?ney ao?o/aiiy -neaaeee iiceoeaiee ei?aeyoe?e-iee
ca’ycie. A o?e aea a?oi? i?ae iiaeeiaiiyi oeueo?acaoeo a ia?o? o?e aeiae
? i?e cae?i/aii? niinoa?aaeaiiy iaea i?noea neeueia i?yia iaaaoeaia
ei?aeyoe?y.

Oaaeeoey 3.

Neea oa iai?aaeai?noue ei?aeyoe?eiiai ca’yceo cia/aiue eio?oe??ioa
iiaeeiaiiy oeueo?acaoeo ia i?ioyc? e?eoaaiiy oai?eo ia ?ae oeoiea.

A?oie oai?eoEiao?oe??io ei?aey-oe?? cia/aiue eiao?-oe??ioa iiaeeiaiiy
oeueo?acaoeo aei iia?aoe?? oa ia?o? 3 aeiae i?ney iia?aoe??Eiao?oe??io
ei?aeyoe?? cia/aiue eiao?oe??ioa iiaeeiaiiy oeueo?acaoeo a ia?o? 3 aeiae
i?ney iia?aoe?? oa i?e cae?i/aii? niinoa?aaeaiiyOai??, ui ia iaee
oneeaaeiaiue e?eoaaiiy M=-0.710.2

t=3.55

p 95%M=+0.780.156

t=5.0

p 95%Oai??, e?eoaaiiy yeeo oneeaaeieeinueM=0.093M=-0.9990.199

t=5.0

p 99%

I?e a?aenooiino? oneeaaeiaiue e?eoaaiiy o oai?eo caa??aa?oueny no?eea
oaiaeaioe?y aei i?aeaeuaiiy eiao?oe??ioa iiaeeiaiiy oeueo?acao-eo a
ne?iaaooe? e?ia? i?ney iia?aoe??. Iaoiae ?aaao? ia noai oai?iai, eiee
ee?i?/ii ? a?io?i?/ii ci?ie ua ia i?iyaeeenue.

Iaoiae oeueo?acaoeiai? niaeo?ineii?? ne?iaaoee e?ia? oai?eo ia ?ae
oeoiea ia /anoioao 10, 30, 50, 70, 90, 110 IAoe oa 5, 15, 25, 35, 45,
55 IAoe aeicaiey? ?a?no?oaaoe ci?ie a noai? oai?iai a?aeii-a?aeii ??aith
?ioieneeaoe??. Ci?ie eiao?oe??ioa iiaeeiaiiy oeueo?acao-eiai? oaee?,
ye? aeeeeeathoueny caiaeueieie oneeaaeiaiiyie (ia?eoi-i?o, iaie?aaoeo,
caiaeaiiy eaaai?a), i?ioiaeyoue iaeiioeiii, ui iiae-ia iiynieoe
oi?aa?naeueieie ci?iaie eiioi?iaoe?eiiai oa?aeoa?o neeaaeiaeo /anoei
ne?iaaoee e?ia? i?e aiaeioieneeic? ??ciiai aaia-co. Iia?aoe?y oa ia?eic
i?ecaiaeyoue aei ciaioaiiy eiao?oe??ioa iiaeeiaiiy oeueo?acaoeo (ia
/anoioao 30, 70 IAoe 5-20 iaeeieoeue), i?e caaeia?eueiiio ia?aa?ao
i?neyiia?aoe?eiiai ia??iaeo cia/aiiy eiai iiai?noth a?aeiiaeththoueny.
Iiaeeeaee aa??aio c iia?eueiei cieaeaiiyi (oaeaee?noue 2 iaeeieoeue ia
aeiao), ui oaeiae i?ioiaeeoue aeey oai?iai aac oneeaaeiaiue. I?e cia/i?e
oaeaeeino? cieaeaiiy (oaeaee?noue 6 iaeeieoeue ia aeiao) o oai?iai
aeieea? aaaeea caiaeueia oneeaaeiaiiy, ui i?eaiaeeoue aei nia?o? i?e
iieacieeao eiao?oe??ioa iiaeeiaiiy ia /anoio? 30 IAoe 48-45, ia 50
IAoe 40-35.

Ci?ie, ye? aaeaeiny anoaiiaeoe iaoiaeii oeueo?acaoeiai? niaeo?ineii??,
?a?no?othoueny ia 1-2 aeiae ?ai?oa cae/aeieo ee?i?/-ieo, a oea
a?aee?eaa? iia? iiaeeeaino? uiaei niinoe?aaeaiiy oa e?eoaaiiy oai?eo.
Iieacieee oeueo?acaoeiai? niaeo?ineii?? aeicaieythoue i?iaiicoaaoe
ia?aa?a i?neyiia?aoe?eiiai ia??iaeo oa eiai caiaeueieo oneeaaeiaiue.

Ia i?aenoaa? niinoa?aaeaiue noi?ioeueiaaii oi?ioeo aeiaoiaeo, ia yeee
Iaoeiai-aeine?aeiee oeaio? iaoaioii? aenia?oece Aea?ae-iaoaioo Oe?a?ie
aeaeaa iaoaio [14976 A A61A 8/00 Cayaeaii 05.12.96; Iioae. 04.03.97].

AENIIAEE

1. Aaciina?aaei? ?acoeueoaoe e?eoaaiiy ?aeo oeoiea caeaaeaoue a?ae
aeo?aeiiai ??aiy ?ioieneeaoe??, yeee ciaoiaeeoueny a o?niiio
ni?a-a?aeiioaii? c iioe?ai?noth iieieia?/iiai i?ioeano, eiiiainaoi?-ieie
iiaeeeainoyie i?aai?a ? nenoai i?aai?cio oai?iai oa aaee/e-iith
yo?iaaiieo aieea?a (ia?aaeiia?aoe?eii? i?aeaioiaee, iia?aoea-iiai
ao?o/aiiy- ia’?io oa o?aaiaoe/iino?, a oaeiae ia?eico), ui iiaeooue
ca?eueooaaoe ?ioieneeaoe?th.

2. O aeieeiaii? aiaeioieneeico a i?aai?ci? oai?iai aa?a o/anoue
eiiieaen oaeoi??a, cie?aia aeeoo?ae?yeuei?noue Helycobacter pilori. On?
aeine?aeaeai? oai?? iaee o?aaeaiiy neeciai? iaieiiee oeoieo
Helycobacter pilori. Caa?oaeiai?noue aaeoa???th neeciai? iaieiiee oeoiea
o oai?eo, ui iaee aioo??oiuei/a?aai? oneeaaeiaiiy o??o?a?/iiai e?eoaaiiy
caiaeueiiai oa?aeoa?o aeua, ? neeaea 56 11 i?e?iaieo o?e a iie? ci?o, o
oai?eo, ye? oneeaaeiaiue ia iaee, e?eue-e?noue i?e?ia?a neeaea 127.

3. ?ic?iaeaiee iaoiae e?eoaaiiy oae?eiaaeoa??ico eiiieaenii i?aia?ao?a
c i?io?eaeoe/iith iaoith cieaeo? a?eueo i?ae iaiieiaeio /anoioo
caiaeueieo aioo??oiuei/a?aaieo oneeaaeiaiue o??o?a?/iiai e?eoaaiiy ?aeo
oeoiea.

4. ?aii? aeae?eaiiy a?oie ?eceeo (c o?aooaaiiyi o?aaiaoe/-iino?
iia?aoe??, ae?? ia?eico, ?i?o?eiaaiino? neeciai? iaieiiee oeoi-ea, o./.
?ioieneeaoe?? ??ciiai aaiaco — oaeoi??a, ye? iaoiiaeththoue
iaaeaaii?e?iiee ia?aa?a i?neyiia?aoe?eiiai ia??iaeo) ? ?o ei?aeoe?y
aeicaiey? ciaioeoe e?euee?noue i?neyiia?aoe?eieo ai?eii-caiaeueieo
oneeaaeiaiue ? aecia/eoe no?iee ?aeaia?ioii??, a oaeiae ?acoeueoao
e?eoaaiiy.

5. Aoaeoeai?noue e?eoaaiiy caiaeueiiai oneeaaeiaiiy ye aeaea?aea
?ioieneeaoe?? a /a?aai?e ii?iaeiei? iaoiaeii ?aeaia?ioii?? caeaaeeoue
a?ae /ano ae?? oneeaaeiaiiy- a?ae aeieeiaiiy aei ae?aaiinoeee eiai
ee?i?/ieie ? a?io?i?/ieie iaoiaeaie.

6. Noai neiae?iio aiaeiaaiii? ?ioieneeaoe?? iiaea ?a?no?oaaoenue ca
aeaieie oeueo?acaoeiai? niaeo?ineii??- eiao?oe??ioa iiaeeiaiiy
oeueo?acaoeiai? oaee? a ne?iaaooe? e?ia? oai?iai. *ooeea?noue
iieac-iee?a oeueo?acaoeiai? niaeo?ineii?? cia/ii aeua a?ae a?io?i?/ieo ?
ee?i?/ieo iaoiaeee. Eiao?oe??io iiaeeiaiiy oa aeiaiaa oaeaee?noue eiai
ci?i ?aaao? ia ci?io noaio i?aai?cio ca 1-2 aeiae aei ia?oeo ee?i?/ieo
i?iyaeaiue ? aea? iiaeeea?noue ?aiiuei? ae?aaiinoeee.

7. ?ic?iaeaiee niin?a ae?aaiinoeee i?neyiia?aoe?eieo caiaeueieo
oneeaaeiaiue, iniiaaiee ia aeeiai?/iiio niinoa?aaeaii? ca eiao?oe??ioii
iiaeeiaiiy oeueo?acaoea oa oaeaeeinoth eiai aeiaiaeo ci?i, aeicaiey?
ae?aaiinooaaoe aeieeiaiiy oneeaaeiaiiy ca 2 aeiae aei ia?oeo ee?i?/ieo
i?iya?a.

8. Ci?ie iieaciee?a oeueo?acaoeiai? niaeo?ineii?? i?ioiaeyoue
iaeiioeiii i?e ??cieo aeaeao caiaeueieo oneeaaeiaiue —
i?neyiia?aoe?e-i?e iiaaiii??, iaie?aaoeo?, ia?eoii?o?, ui aeaco? ia
oi?aa?naeuei? iaoai?cie ?icaeoeo oieneeico ??ciiai aaiaco.

I?AEOE*I? ?AEIIAIAeAOe??

?. Oai?ei ia ?ae oeoiea a noaae?? O1-4N1-2M0 iieacaii i?iaa-aeaiiy a
ia?aaeiia?aoe?eiiio ia??iae? eo?no oa?ai?? eiiieaenii i?a-ia?ao?a
(a?eae?i, oao?aoeeee?i, iao?ii?aeacie). Ei?ioea o?eaae?noue eo?no (7
ae?a) aeinoaoiy aeey cieaeaiiy /anoioe caiaeueieo aioo??o-iuei/a?aaieo
oneeaaeiaiue o??o?a?/iiai e?eoaaiiy ?aeo oeoiea. O??o?a?/ia ao?o/aiiy
iioeiaeueii i?iaiaeeoe a ia?o? 7 aei?a i?ney cae?i/aiiy i?io?eaeoe/iiai
e?eoaaiiy oae?eiaaeoa??ico.

??. Aeey ia’?eoeaii? ioe?iee noaio oai?iai aeioe?eueii aeei?enoi-aoaaoe
oeueo?acaoeiao niaeo?ineii?th ne?iaaoee e?ia?, aei??thaaoe eiao?oe??io
iiaeeiaiiy oeueo?acaoeo ? oaeaee?noue ci?ie eiai aaee/e-ie. Cieaeaiiy
eiao?oe??ioa iiaeeiaiiy oeueo?acaoea ia 2-4 iaeeieoe? ia aeiao
na?ae/eoue i?i aeieeiaiiy caiaeueiiai oneeaaeiaiiy, yea ia i?yoyc? 1-2
ae?a iiaeia ae?aaiinooaaoe ee?i?/ieie ? a?io?i?/ieie iaoiaeaie.
Iaoiaeeea aeicaiey? ao?ooeoenue o i?ioean aeieeiaiiy oneeaaeiaiiy aei
?icaeoeo ee?i?/ieo i?iya?a iie?i?aaiii? iaaei-noaoiino?.

Nienie ?ia?o, iioae?eiaaieo ca oaiith aeena?oaoe??

1. Iineaeaiei I.A. Caiaeuei? oneeaaeiaiiy o??o?a?/iiai e?eoaaiiy ?aeo
oeoiea oa aeiaeaoeia? iiaeeeaino? a ?o ae?aaiinoeoe? //Aanoi. i?iaeai
aeieiaee e iaaeeoeeiu.-1998.-?4.-N.116-124.

2. Iineaeaiei I.A. E?eoaaiiy oae?eiaaeoa??ico a i?io?eaeoeoe?
i?neyiia?aoe?eieo caiaeueieo aioo??oiueii/a?aaeiieo oneeaaeiaiue o
oai?eo ia ?ae oeoiea //E?ea?nueea ni?aaa.-1998.- ?2.- N.132- 134.

3. Iineaeaiei I.A. Iiaeeeaino? oeueo?acaoeiai? niaeo?ineii?? ne?iaaoee
e?ia? a ae?aaiinoeoe? ?aii?o i?neyiia?aoe?eieo caiaeueieo oneeaaeiaiue o
oai?eo ia ?ae oeoiea //Ee?i?/.o??o?a?y.-1998.-? 3.-N. 38-39.

4. Iineaeaiei I.A. Nai?/ani?noue ?aeaia?ioii?? i?e oneeaaeiaiiyo
o??o?a?/iiai e?eoaaiiy ?aeo oeoiea // Iaoa??aee eiio.»Aeooaeuei?
ieoaiiy oai?aoe/ii? oa ee?i?/ii? iaaeeoeeie ia no/aniiio ??ai?».-
Iieoaaa.- 1996.- N.272.

5. Iineaeaiei I.A., Caeea/ee I.I., ?oaeaiei I.I., Nia?ea/ A.N. Niin?a
ae?aaiinoeee caiaeueieo oneeaaeiaiue i?ney o??o?a?/iiai e?eoaaiiy ?aeo
oeoiea /14976 A A61A 8/00 Cayaeaii 05.12.96; Iioae.04.03.97.

6. Oaeaoei I.A., A?otho A.O., Iineaeaiei A.A. E aii?ino i
iineaiia?aoeeiiiuo iaie?aaoeoao i?e oe?o?ae/aneii ea/aiee ?aea aeaeoaeea
// Iaoa??aee iaoeiai-i?aeoe/ii? eiioa?aioe?? iieieia?a Oe?a?ie »Oeyoe
ai?iaaaeaeaiiy iaea?eueo aoaeoeaieo iaoiae?a iae?eo oa e?eoaaiiy
iieioai?eo» Aeiiaoeuee.- 1993.-N.225.

7. Oaeaoei I.A., Iineaeaiei I.A. Aeiey oai?eo i?ney ia?aianaiiy
i?neyiia?aoe?eieo oneeaaeiaiue o??o?a?/iiai e?eoaaiiy ?aeo oeoiea//
Iaoa??aee eiio.»Aeooaeuei? ieoaiiy oai?aoe/ii? oa ee?i?/ii? iaaeeoeeie
ia no/aniiio ??ai?».-Iieoaaa.-1996.-N.454.

Aiioaoe?y

Iineaeaiei I.A. ‘’Ae?aaiinoeea, i?io?eaeoeea ? e?eoaaiiy ?aii?o
i?neyiia?aoe?eieo aioo??oiuei/a?aaieo oneeaaeiaiue i?e o??o?a?/iiio
e?eoaaii? ?aeo oeoiea (ee?i?ei-eaai?aoi?ia aeine?aeaeaiiy)’’.- ?oeiien.

Aeena?oaoe?y ia caeiaoooy a/aiiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca
niaoe?aeuei?noth 14.01.07- iieieia?y.- ?inoeooo aenia?eiai-oaeueii?
iaoieia??, iieieia?? ? ?aae?ia?ieia?? ?i.?.A.Eaaaoeueeiai IAI Oe?a?ie,
Oe?a?inueeee iaoeiai-aeine?aeiee ?inoeooo iieieia?? oa ?aae?ieia?? IIC
Oe?a?ie, Ee?a, 1998.

Aeena?oaoe?th i?enay/aii ae?aaiinoeoe?, i?io?eaeoeoe? ? e?eoaaiith
?aii?o i?neyiia?aoe?eieo oneeaaeiaiue i?e ?aaeeeaeueiiio e?eoaaii? ?aeo
oeoiea. ?ic?iaeaia iaoiaeeea i?io?eaeoeee ?aii?o caiaeueieo oneeaaeiaiue
ia?aaeiia?aoe?eiei e?eoaaiiyi oae?eiaaeoa??ico eii-ieaenii i?aia?ao?a,
ui cieaeo? /anoioo caiaeueieo, aioo??oiuei/a-?aaieo oneeaaeiaiue
iaiieiaeio. Aea/aiee ca iaoiaeeeith oeueo?a-caoeiai? niaeo?ineii??
ne?iaaoee e?ia? eiao?oe??io iiaeeiaiiy oeueo?acaoeo ? oaeaee?noue ci?ie
iiaeeiaiiy, ui aeicaieeei ?ic?iaeoe niin?a ae?aaiinoeee
i?neyiia?aoe?eieo oneeaaeiaiue ?aaeeeaeueiiai o?-?o?a?/iiai e?eoaaiiy
?aeo oeoiea. Niin?a aeniei/ooeeaee, aeicai-ey? ae?aaiinooaaoe
iayai?noue oneeaaeiaiue ca aea? aeiae aei ia?oeo ee?i?/ieo i?iya?a.

Eeth/ia? neiaa: ?ae oeoiea, oneeaaeiaiiy o??o?a?/iiai e?eoaai-iy,
oae?eiaaeoa??ic, oeueo?acaoeiaa niaeo?ineii?y, ne?iaaoea e?ia?.

Aiiioaoeey

Iineaeaiei A.A. ’’Aeeaaiinoeea, i?ioeeaeoeea e ea/aiea ?aiieo
iineaiia?aoeeiiiuo ineiaeiaiee i?e oe?o?ae/aneii ea/aiee ?aea aeaeoaeea
(eeeieei-eaai?aoi?iia enneaaeiaaiea)’’.- ?oeiienue.

Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo
iaoe ii niaoeeaeueiinoe 14.01.07-iieieiaey.- Einoeooo yenia?eiaioaeueiie
iaoieiaee, iieieiaee e ?aaeeiaeieiaee ei.?.A.Eaaaoeeiai IAI Oe?aeiu,
Oe?aeineee IEE iieieiaee e ?aaeeieiaee IIC Oe?aeiu, Eeaa, 1998.

Aeenna?oaoeey iinayuaia aeeaaiinoeea, i?ioeeaeoeea e ea/aieth ?aiieo
iineaiia?aoeeiiiuo ineiaeiaiee i?e ?aaeeeaeueiii ea/aiee ?aea aeaeoaeea.
?ac?aaioaia iaoiaeeea i?ioeeaeoeee ?aiieo ainia-eeoaeueiuo ineiaeiaiee
i?aaeiia?aoeeiiiui ea/aieai oaeeeiaaeoa-?eica eiiieaenii i?aia?aoia,
nieaeathuay /anoioo ineiaeiaiee iaiieiaeio. Eco/ai ii iaoiaeeea
oeueo?acaoeiaie niaeo?ineiiee nuai?ioee e?iae eiyoeoeeaio iiaeiuaiey
oeueo?acaoea e nei?inoue eciaiaiey iiaeiuaiey, /oi iicaieeei
?ac?aaioaoue niinia aeeaaiin-oeee ?aiieo iineaiia?aoeeiiiuo
ainiaeeoaeueiuo ineiaeiaiee ?aaeeeaeueiiai oe?o?ae/aneiai ea/aiey ?aea
aeaeoaeea. Niinia auni-ei/oanoaeoaeai, iicaieyao aeeaaiinoe?iaaoue
iaee/ea ineiaeiaiee ca aeaia nooie aei ia?auo eeeie/aneeo i?iyaeaiee.

Eeth/aaua neiaa: ?ae aeaeoaeea, ineiaeiaiey oe?o?ae/aneiai ea/aiey,
oaeeeiaaeoa?eic, oeueo?acaoeiaay niaeo?ineiiey, nuai?ioea e?iae.

Abstract

Moskalenko O.V. Diagnostics, prevention and treatment of early
afteroperational complications upon surgical treatment of stomach cancer
(clinical and laboratory research).- Manuscript.

Thesis for the scientific degree of Candidate of Medical Sciences on
a specialiti 14.01.07 — oncology.- R.E.Kavetsky Institute of
Experimental Pathology, Oncology and Radiobiology of National Academy of
Sciences of Ukraine, Institute of Oncology and Radiology of Health Care
of Ukraine, Kyiv, 1998.

The thesis is dedicated to diagnostics, prevention and treatment of
early inflammatory complications upon radical operative treatment of
stomack cancer. This method of preoperative treatment of
helicobacteriosis by complex of drugs has been elaborated. It reduces
preparations of complications by 1/2. By means of method of ultrasonic
spectroscopy of blood serum we have studied the ratio of absorption of
ultrasonic waves and the alteration rate of absorption. This research
has allowed to develop the way of diagnostics of early afteroperational
inflammatory complications that may occur upon surgical treatment of
stomach cancer. Our technique is highly sensitive and allows to diagnose
the presence of complications two days prior to the first clinical
manifestation.

Key words: stomach cancer, complications of surgical treatment,
heliobacteriosis, ultrasonic spectroscopy, blood serum.

I?aeienaii aei ae?oeo 2.11.98 ?. Oi?iao 60o90/16

Oi. ae?oe. a?e. 1,0. Iae. aeae. a?e. 1,0.

Iaeeaae 100. Cai. 214

______________________________________

314000, i. Iieoaaa, aoe. *aia?aa, 3.

Iaeioe?aaeia iia?aoeaia iie?a?ao?y.

OAe NOAI?NEAA.

7-18-36

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