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Частота, клініко-імунологічні особливості та прогнозування медикаментозної алергії у осіб, що піддалися анестезії: Автореф. дис… канд. мед. наук / А

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AEAAeAI?ss IAAeE*IEO IAOE OE?A?IE ?INOEOOO OOEC?AO??? ? IOEUeIIIIEIA??
?i.O.A.ssIIANUeEIAI

Aa?a?iie Aiae??e ?aaiiae/

OAeE : 616-009-:615.45

*anoioa, ee?i?ei-?ioiieia?/i? iniaeeaino? oa i?iaiicoaaiiy

iaaeeeaiaioicii? aea?a?? o in?a, ui i?aeaeaeeny aianoac??

14.01.29 – ee?i?/ia ?ioiieia?y

Aaoi?aoa?ao aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

Ee?a – 1999

Aeena?oaoe??th ? ?oeiien

?aaioa aeeiiaia a A?iieoeueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?
?i.I.?.Ie?iaiaa IIC Oe?a?ie

Iaoeiaee ea??aiee: aeieoi? iaaee/ieo iaoe Caeeia Na?a?e A?eoi?iae/,
A?iieoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao ?i. I.?.Ie?iaiaa IIC
Oe?a?ie, eaoaae?a ooec?ao??? c eo?nii ee?i?/ ii? ?ioiieia?? oa
aea?aieia??, aeioeaio.

Io?oe?ei? iiiiaioe: aeieoi? iaaee/ieo iaoe, noa?oee iaoeiaee
ni?a?ia?oiee Aoii?ia Aaeeia Ai?en?aia, Iaoe?iiaeueiee iaaee/iee
oi?aa?neoao ?i.I.I.Aiaiiieueoea, Iaoeiai-aeine?aeiee eaai?aoi?iee
oeaio?, eaai?aoi??y ee?i?/ii? ?ioiieia??, caa?aeoth/a; aeieoi? iaaee/ieo
iaoe, i?ioani? Iaeueieeia Ieaa Oaiaein?eiae/, Ee?anueeee
iaoeiai-aeine?aeiee ?inoeooo ioiea?eiaieia?? ?i.I.N.Eieii?e/aiei IIC
Oe?a?ie, eaai?aoi??y iaoio?c?ieia?? oa ?ioiieia??, caa?aeoaa/.

I?ia?aeia onoaiiaa: Aeiiaoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao IIC
Oe?a?ie, eaoaae?a ee?i?/ii? ?ioiieia?? oa aea?aieia??.

Caoeno a?aeaoaeaoueny “29” aa?aniy 1999 ?. i13 aiaeei? ia can?aeaii?
niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.552.01. i?e ?inoeooo? ooec?ao??? ?
ioeueiiiieia?? ?i.O.A.ssiianueeiai AII Oe?a?ie (252110,i.Ee?a, INI-680,
oca?c I?ioan?a y?,7).

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeooo? ooec?ao???
? ioeueiiiieia?? ?i.O.A.ssiianueeiai AII Oe?a?ie (i.Ee?a,oca?c I?ioan?a
y?,7).

Aaoi?aoa?ao ?ic?neaiee “25” na?iiy 1999 ?.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee AE.A.Aaaioe?aa

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue i?iaeaie. A inoaii? ?iee aea?a?/ii caoai?thaaiiy (AC)
oa?eoee aei /enea iaeaieueo ?iciianthaeaeaiieo [A.I.Iooeee oa ?i.,1998;
TH.E.Oauaiei e ae?.,1999]. Ca ioe?ieaie oao?aoe?a [A.I.Iaiueei,1997;
I.E.Eaneoea,1998] aiie iin?aeathoue o?ao? i?noea o no?oeoo??
caoai?thaaiue i?ney oai?ia na?oeaai-noaeeiii? nenoaie ? iieieia?/ii?
iaoieia??.

A no?oeoo?? AC [N.A. Oaaei?iae/,1991; A.I. Iooeee oa ?i.,1993; I.A.
Aiiaea?/oe,1995] iaaeeeaiaioicia aea?a?y (IA) neeaaea? a?ae 14.4 aei
33.0%. I?e/iio, ca aeaieie A.E. Nieieiaie [1990], A.N.Eiiaoeia [1992] a
oa?aiaaoe/i?e ee?i?oe? /anoioa IA noaiiaeoue 1 – 5%, a na?aae iia?/ii?
ae?? iaaeeeaiaioicieo i?aia?ao?a acaaae? aiia caeia? a?ey 66%
[A.E.Iuoeeee e ae?., 1991; A.N.Eiiaoei,1992].

A no/ani?e iaoeia?e e?oa?aoo?? [Aeae.O.Eaae,1990; H.Mitsuhata et
al.,1992; A.A.Oaaeinaaa e ae?.,1995] ana /ano?oa c’yaeythoueny aeai?
a?aeiinii aaaeeeaino? i?iaeaie IA na?aae oai?eo, yeei aoea i?iaaaeaia
aianoac?y. A?aeiii, ui ii iaeei ie?aii acyoee aianoaoee ia iiaea
aaeaeaaoii caaacia/eoe oni eiiiiiaioe aianoaci? – aiiiioe/iee nii,
iae?ii’yciao aeieaaeo i aiaeueaacith. Oea ciaia’yco? oao?aoe?a
canoiniaoaaoe i?ae /an iia?aoe?? a?ae 5 aei 14 iaaeeeaiaioicieo
i?aia?aoia c ??ciiieaiiaith aei?th. Aaaaeaiiy a i?aaiici oai?iai oaei?
e?eueeino? iaaeeeaiaioicieo niieoe, a oaeiae aaeeea eieueeinoue
iia?aoeaieo ao?o/aiue i?ae ia?eicii (iiiaae 2 iei.o ??e a Oe?a?i? oa 45
000 o A?iieoeueei? iaeano?) noai?ththoue i?iaeaio ?icaeoeo IA i?e
i?iaaaeaii? aianoac?? ua a?eueo aeooaeueiith [Aeae.O.Eaae,1990; J.L.
Theissen et al.,1995; E.A.Neeeia,1998].

A?eueo?noue oao?aoe?a aaaaeathoue, ui IA i?ae /an aianoac?? aeieea?
/ano?oa o aeaeyae? aiao?eaeoe/iiai oieo, a?iioi- aai ea?eiainiacio,
oe??ieo i?iya?a, ae?aaiinoeea yeeo aeineoue neeaaeia ? iio?aao?
i?iaaaeaiiy eiiieaeniiai aea?ai-?ioiieia?/iiai ianoaaeaiiy oai?eo
[A.N.Eiiaoei,1992; E.A.Iao?ia e ae?.,1992; N.A.Caeeia,1996]. Ne?ae
i?aee?aneeoe, ui oey i?iaeaia a aianoac?ieia?? ii?aeio?oueny c? cia/ieie
o?oaeiiuaie c o?aooaaiiyi oiai, ui i?ae /an ia?eico iaoe??io
ciaoiaeeoueny i?ae iaaeeeaiaioiciith naaeaoe??th oa i?i?aeaenaoe??th,
ye? cia/ii oneeaaeiththoue ioe?ieo ee?i?/iiai ia?aa?ao IA i?ae /an
iia?aoeaiiai ao?o/aiiy [Aeae.O.Eaae,1990; O.R.Hung,1994]. Iaiao?aeii
oaeiae aeiaeaoe, ui a e?oa?aoo?? iaeaea a?aenooi? no/ani? aeai? i?i
/anoioo, ao?ieia?/io no?oeoo?o, ee?i?ei-?ioiieia?/i? iniaeeaino?,
iiaeeea?noue i?iaiicoaaiiy ?icaeoeo IA i?ae /an ciaaiethaaiiy. A Oe?a?i?
oae? ?iaioe iaeaea a?aenooi?. Oaeei /eiii, c o?aooaaiiyi anueiai
aeuaiaaaaeaiiai ne?ae aaaaeaoe ieoaiiy IA a aianoaciieiai? aeooaeueiith
iaoeiaith oa i?aeoe/iith i?iaeaiith, yea iio?aao? iiaeaeueoiai aea/aiiy.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. ?iaioa a
o?aaiaioii eiieo?nii? aea?aeathaeaeaoii? oaie eaoaae?e ooec?ao??? c
eo?nii ee?i?/ii? ?ioiieia?? oa aea?aieia?? A?iieoeueeiai aea?aeaaiiai
iaaee/iiai oieaa?neoaoo ?i.I.?.Ie?iaiaa ca caiiaeaiiyi IIC Oe?a?ie:
“Ai?aeai?ieia?/ia aeine?aeaeaiiy aea?a?/ieo caoai?thaaiue
iaaio?iiiaaiiiai oa aio?iiiaaiiiai aaiaco” [N aea?ae?a?no?aoe?? 01.9.10
026085].

Iaoa aeine?aeaeaiiy. Iie?ioeoe ae?aaiinoeeo oa i?iaiicoaaiiy
iaaeeeaiaioicii? aea?a?? o in?a, ui caciaee aianoac??.

Caaaeaiiy aeine?aeaeaiiy. 1) Aecia/eoe /anoioo i no?oeoo?o
iaaeeeaiaioicii? aea?a?? a aianoaciieiai/iie i?aeoeoei ca aeaieie
?ao?iniaeoeaiiai aiae?co iaoa??ae?a ?noi??e oai?ia iaoe??io?a, ui
caciaee aianoac??.2) Aea/eoe ee?i?ei-?ioiieia?/i? iniaeeaino? ia?aa?ao
iaaeeeaiaioicii? aea?a??, ui ?icaeioeany i?ae /an i?iaaaeaiiy ia?eico.3)
Aecia/eoe e?eoa??? i?iaiicoaaiiy ?eceeo aeieeiaiiy iaaeeeaiaioicii?
aea?a??o oai?eo, yeei ia?aaeaa/a?oueny i?iaaaeaiiy ciaaiethaaiiy.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a. Aia?oa ia cia/iiio eeii?/iiio
iaoa?iaei aea/aia /anoioa iaaeeeaiaioicii? aea?a?? o in?a, ui
i?aeaeaeeny ciaaiethaaiith i?ae ??ciiiai?oieie aeaeaie aianoac??.
Aecia/aia ao?ieia?/ia no?oeoo?a iaaeeeaiaioicii? aea?a?? oa
eeii?ei-iioiieiai/ii iniaeeainoi ?? ia?aa?ao o iaoe??io?a, ui caciaee
aianoac??. ?ic?iaeaii e?eoa??? i?iaiicoaaiiy ?eceeo ?icaeoeo
iaaeeeaiaioicii? aea?a?? o in?a i?ae /an i?iaaaeaiiy ia?eico.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a. Io?eiai? aeai? a?aeiinii
/anoioe, ao?ieia?/ii? no?oeoo?e, ee?i?ei – ?ioiieia?/ieo iniaeeainoae
iaaeeeaiaioicii? aea?a?? o oai?eo, ui caciaee iia?aoeaiiai ao?o/aiiy
i?ae aianoac??th, aeicaieythoue nooo?ai iie?ioeoe ye?noue ae?aaiinoeee
iaaeeeaiaioicii? aea?a?? ? aoaeoeai?noue e?eoaaiiy a?aeiia?aeii?
eaoaai??? in?a. ?ic?iaeaia eiii’thoa?eciaaia i?ia?aia i?iaiicoaaiiy
?eceeo aeieeiaiiy iaaeeeaiaioicii? aea?a?? o oeueiai eiioeiaaioo oai?eo,
yea iiaea aooe ?aaeueii ao?eaia o i?aeoeeo caeeaae?a ioi?iie caei?ia’y,
ui aoaea ni?eyoe i?aeaeuaiith aoaeoeaiino? i?io?eaeoeee ?icaeoeo
iaaeeeaiaioicii? aea?a?? o in?a, ui i?aeeyaathoue iia?aoeaiiio
ao?o/aiith i?e aeei?enoaii? ??cieo aeae?a aianoac?ieia?/iiai
caaacia/aiiy.

Iniaenoee aianie caeiaoaa/a. Iniaenoee aianie aaoi?a iieyaa? a
i?iaaaeaii? ee?i?/iiai ianoaaeaiiy oai?eo (100%), eaai?aoi?iiai
aea?aieia?/iiai ianoaaeaiiy iaoe??io?a (60%), eaai?aoi?iiai
?ioiieia?/iiai ianoaaeaiiy (25%), noaoenoe/i?e ia?iaoe? iaoa??ae?a
aeine?aeaeaiiy (100%), ?ic?iaoe? eiii’thoa?ii? i?ia?aie i?iaiicoaaiiy
?eceeo ?icaeoeo iaaeeeaiaioicii? aea?a?? o in?a, ui i?aeeyaathoue
iia?aoeaiiio ao?o/aiith i?ae aianoac??th (90%). An? iaoeia? ?acoeueoaoe
aeine?aeaeaiue, ye? aeiinyoueny ia caoeno, io?eiai? aaoi?ii naiino?eii.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iaoa??aee ? iniiai? iieiaeaiiy
?iaioe aeiiia?aeaeeny ia eiioa?aioe?yo iieiaeeo a/aieo A?iieoeueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo [A?iieoey, 1995,1996], caniaeaiiyo
iaeanieo iaoeiaeo anioe?aoe?e ooec?ao??a, ioeueiiiieia?a, iioiieiaia ?
aea?aieia?a oa aianoaciieiaia-?aai?iaoieia?a [A?iieoey,1998], I
iaoe?iiaeueiiio eiia?an? Oe?a?ie c ?ioiieia??, aea?aieia?? oa
?ioii?aaa?e?oaoe?? [Aeoooa, 1998], II c’?cae? ooec?ao??a ?
ioeueiiiieia?a Oe?a?ie [Ee?a,1998], iaoeia?e eiioa?aioe??, i?enay/ai?e
10-??//th ee?i?/ii? e?ea?i? N8 i.Ee?aa [Ee?a,1998].

Ioae?eaoe??. Iaoa??aee aeena?oaoe?? aeeeaaeai? o 7 ioae?eaoe?yo: noaoae
o iaoeiaeo aeaeaiiyo – 4, oacao iaoa??ae?a c’?cae?a oa eiioa?aioe?e – 2,
ca??ieeao iaoeiaeo i?aoeue – 1.

Ai?iaaaeaeaiiy a i?aeoeeo. Iaoa??aee aeine?aeaeaiiy ai?iaaaeaeai? a
?iaioo ?ioiieia?/iiai oeaio?o A?iieoeueeiai iaeaniiai
i?ioeooaa?eoeueiciiai aeeniaina?o, aea?aieia?/iiai eaa?iaoo A?iieoeueei?
iaeanii? ee?i?/ii? e?ea?i? ?i.I.?.Ie?iaiaa, a?aeae?eaiue ?aai?iaoe?? oa
aianoac?ieia?? A?iieoeueei? iaeanii? ee?i?/ii? e?ea?i? ?i.I.?.Ie?iaiaa
oa A?iieoeueeiai ?aeiiiai oa?eoi??aeueiiai ee?i?/iiai iaaee/iiai
ia’?aeiaiiy. Iaoa??aee aeine?aeaeaiue oaeiae aeei?enoiaothoueny i?e
/eoaii? eaeoe?e e?ea?yi OOE oa nooaeaioai ia eaoaae?? ooec?ao??? c
eo?nii ee?i?/ii? ?ioiieia?? oa aea?aieia?? ? ia eaoaae?? caaaeueii?
o??o?a?? c eo?nii aianoac?ieia?? oa ?ioaineaii? oa?ai?? A?iieoeueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i.I.?.Ie?iaiaa.

Ianya oa no?oeoo?a aeena?oaoe??. ?iaioa aeeeaaeaia ia 135 noi??ieao
iaoeiiieno, ?ethno?iaaia 16 oaaeeoeyie, 15 ?enoieaie, Aeena?oaoe?y
neeaaea?oueny c anooio, iaeyaeo e?oa?aoo?e, iaoa??ae?a oa iaoiae?a
aeine?aeaeaiiy, 3 ?icae?e?a aeanieo aeine?aeaeaiue, caeeth/aiiy,
aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e, aeac?aieea e?oa?aoo?e, yeee
aeeth/a? 227 ?ia?o, o oiio /ene? 78 a?o/eciyieo, 98 e?a?i NIAe, 51
?iicaiieo aaoi??a.

CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy. Aeey ae??oaiiy caaaeaiue ye?
iinoaaeai? a ?iaio? iaie iniaenoi aoei i?iaaaeaii a?aeiia?aeia
aeine?aeaeaiiy 426 in?a, ui ciaoiaeeeeny ia e?eoaaii? o o??o?a?/iiio
a?aeae?eaii? A?iieoeueei? iaeanii? ee?i?/ii? e?ea?i? ia i?ioyc? 1998 ?.
? caciaee iia?aoeaiiai ao?o/aiiy i?ae aiaeio?aoaaeueiei ia?eicii. E??i
iniaenoiai aeine?aeaeaiiy iaoe??io?a, ye? aoee i?iiia?iaai? i?ae
aiaeio?aoaaeueiei ia?eicii, iaie aoa i?iaaaeaiee ?ao?iniaeoeaiee aiae?c
iaoa??ae?a ?noi??e oai?ia 1637 iaoe??io?a, ui ciaoiaeeeeny ia e?eoaaii?
a o??o?a?/iiio a?aeae?eaii? A?iieoeueei? iaeanii? ee?i?/ii? e?ea?i? ia
i?ioyc? 1997-1998 ??..

Aea/aiiy ao?ieia?/ii? no?oeoo?e IA na?aae iaoe??io?a, ui i?aeaeaeeny
aianoac??, i?iaiaeeeiny iaie ca aeiiiiiaith o?aaeeoe?eieo a aea?aieia??
oa ?ioiieia?? iaoiae?a aeine?aeaeaiiy. Noaia ianoaaeaiiy oe??? eaoaai???
oai?eo aeeth/aea cae?aiiy aea?aieia?/iiai aiaiiaco ca?aeii oi?o?eiaai?e
aieao?-iieooaaeueieea [A.I.Iooeee,1992], aea/aiiy iniaeeainoae
ee?i?/iiai ia?aa?ao ia?eico a eiaeiiio ie?aiiio aeiaaeeo, oice/ia
ianoaaeaiiy oai?eo, eaai?aoi?i? aea?aieia?/i? oa ?ioiieia?/i?
aeine?aeaeaiiy. C iaoith aecia/aiiy aiia?/ooeeainoi i?aai?cio
ianoaaeaieo aei iaaeeeaiaioicieo i?aia?ao?a, ye? aoee canoiniaai? i?e
i?iaaaeaii? ia?eico (ao?ii?i, ae?iaae?ie, e?aeiea?i, o?iiaioae, eaoai?i,
ae?oee?i, a?aeoai, oaioai?e), iaie aoee canoiniaai? ?aaeoe?y
aeaa?aioeyoe?? iianenoeo ee?oei ca Oaee?, ?aaeoe?y iiaiaioei? iia?aoei?
eaeeioeeoia [A.O.Oaaeinii, 1982], aecia/aiiy iieacieea iioeiaeaeaiiy
iaeo?io?e?a [A.A.O?aaeeei,1985], iaoiae ?ioiioa?i?noiiao??? c
aiaeiiaiaeieie iaaeeeaiaioicieie i?aia?aoaie [N.A.Caeeia,1995]. Iaie ia
aeiaaeeiai c iaoith aecia/aiiy aiia?/ooeeainoi aei iaaeeeaiaioicieo
i?aia?aoia ia canoiniaoaaeenue oei?ii oanoe, ineieueee ca aeaieie
aieueoinoi oaoiaoeia-aea?aieia?a [A.E.Iuoeeee, 1991; A.I.Iooeee,1992;
A.E.Nieieiaa,1998] aiie iathoue aeineoue iaaenieo iioi?iaoeaiinoue, a
oaeiae iiaeooue aooe iaaacia/ieie aeey aiaeiiaiaeii? eaoaai?i?
ianoaaeaieo, caeaoi? aeeeeeaoe aeiaeaoeiao nainea?e?caoe?th aei e?e?a
oiui. C iaoith ?ioiieia?/iiai ianoaaeaiiy iaie aoa canoiniaaiee eiiieaen
oi?o?eiaaieo oano?a 1 oa 2 ??aiy ca iaoiaeeeaie, ui iaaaaeai?
E.O.*a?iooaiei oa ni?aaao.[1988,1990]. Aecia/aiiy ?ioiieia?/ieo
iaoai?ci?a ?icaeoeo IA o ianoaaeaieo iaie oai?eo i?iaiaeeeiny ?c
aeei?enoaiiyi eeaneo?eaoe?? Aeaeaeea-Eoiana [1975]. Io?eiai? ?acoeueoaoe
aeine?aeaeaiue aoee ia?iaeai? ca aeiiiiiaith iaoiae?a aa??aoe?eii?
noaoenoeee. Aeinoia??i?noue ?ica?aeiinoae aecia/aeany /a?ac e?eoa??e
Nouethaeaioa (t) ? ioe?ithaaeany ca aeiiiiiaith aeia??/i? a??ia?aeiino?
?. ?ica?aeiino? aaaaeaeeny aeinoia??ieie i?e ?0.05 aeey an?o aeiaaee?a).
Na?aae oeeo eaoaai??e in?a i?noeaaa ciaaiethaaiiy aoei cae?eniaii o 312
in?a (19.06%), aioo??oiueiaaiia aianoac?y – o 308 in?a (18.81%),
nieiiiiiceiaa aianoac?y o 157 in?a (9.59%), aiaeio?aoaaeueiee ia?eic – o
860 in?a (52.54%).

I?e aea/aii? iaoa??ae?a i?iaaaeaiiy aianoac?ieia?/iiai caaacia/aiiy ie
a?ae?a?aee aeiaaeee oneeaaeiaiue, ye? iaee i?noea i?ae /an i?iaaaeaiiy
ia?eico. Oaeei /eiii, aiae?c aeaieo ?ao?iniaeoeaiiai aeine?aeaeaiiy,
iieacaa, ui caaaeueia /anoioa oneeaaeiaiue o ianoaaeaieo oai?eo i?ae /an
i?iaaaeaiiy aianoac??, neeaea 10.45% (171 c 1637) iaoe??io?a, ye?
iia?oaaeeny i?ae aoaeue-yeith aianoac??th, aea iaeaea an? oe? aeiaaeee
(169 c 860) noinoaaeeny iaoe??io?a, o yeeo iia?aoeaia ao?o/aiiy
i?iaiaeeeiny i?e aeei?enoaii? aiaeio?aoaaeueiiai ia?eico (19.65%
niinoa?aaeaiue), oiio a iiaeaeueoiio ie i?iaiae?coaaee naia aeiaaeee
oneeaaeiaiue i?e i?iaaaeaii? oeueiai aeaeo aianoac?ieia?/iiai
caaacia/aiiy. I?e aea/aii? iaoa??ae?a ?noi??e oai?ia aeuacacia/aieo
iaoe??io?a ie aeiaeaoeiai i?iaaee a?aea?? oeo aeiaaee?a, a yeeo i?ae /an
i?iaaaeaiiy aianoac?? o oai?eo aeieeaee o? /e ?io? oneeaaeiaiiy, ye?
iiaeii aoei ca’ycaoe c aaeeaaiiyi a?aeiia?aeieo iaaeeeaiaioicieo
cania?a. I?e oeueiio a?aoiaoaaeeny oae? neiioiie ?icaeoeo aea?a?/ieo
?aaeoe?e i?ae /an i?iaaaeaiiy ia?eico [Aeae.O.Eaae,1990; J.Birnbaum,
1994; M.C.Laxenaire, 1996] ye ?aioiaa ii/a?aii?iiy oe??e, iaa?ye iaee//y
oa/aai iiyaa ia o?e? ?ioaineaii caaa?aeaiiai o?o?ea?iiai aeneio, ??cea
cieaeaiiy a?oa??aeueiiai oeneo c ii?ooaiiyi aaiiaeeiai?ee, a?iioi- aai
ea?eiainiaci. Oaeiae c iaoith ?iciaaeoaaiiy oiene/ieo oa aea?a?/ieo
?aaeoe?e ia iaaeeeaiaioici? i?aia?aoe iaie canoiniaai? caaaeueiii?eeiyo?
a aea?aieia?? e?eoa??? [A.I.Iooeee,1989; A.E.Iuoeeee,1991;
N.A.Oaaei?iae/,1994]. Aiae?c ?ao?iniaeoeaieo aeaieo iieacaa, ui eeoa 84
c 169 aeiaaee?a oneeaaeiaiue (49.70% niinoa?aaeaiue) i?ae /an ia?eico
iiaeia aoei a?aeianoe c aeinoaoi?i nooiaiai aeinoia??iino? aei ee?i?/ieo
oi?i IA. Na?aae ieo ia?aaaaeio a?eueo?noue niinoa?aaeaiue (92.86%) ie
a?aeianee aei aiao?eaeoe/iiai oieo, ?io? oi?ie IA (oe??i?, ?ani??aoi?i?)
a?aei?/aeeny cia/ii ??aeoa (1.19% oa 5.95% a?aeiia?aeii, ?0.05), i?ae o
/ieia?e?a (8.33%,14.28% oa 23.81% aiaeiiaiaeii). Oaeei /eiii, na?aae
iaoe??io?a c IA ia?aaaaeaee ae?iee oa /ieia?ee ca a?eii a?ae 46 aei 60
?ie?a oa a?eueoa iaae iniaaie a?eueo iieiaeiai (21-45 ?ie?a) a?eo
(?0.05) iaae
/ieia?eaie. O a?eia?e no?oeoo?? oai?eo oe??? a?oie iniae a?eii 21-45,
46-60, 61 ??e ? a?eueoa cono??/aeeny nooo?ai (?

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