3

I?i?noa?noai ioi?iie caei?ia’y Oe?a?ie A?iieoeueeee iaaee/iee
oi?aa?neoao

?i. I.?. Ie?iaia

IAAAE*OE AANEEUe ?AAIIAE*

OAeE 616-001.17-089

A?IAAEUeAAI?CAOe?ss

A AINO?IIO IA??IAe? II?EIAI? OAI?IAE

14.01.03 — o??o?a?y

Aaoi?aoa?ao aeena?oaoe??

ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

A?iieoey — 1998

Aeena?oaoe??th ? ?oeiien

?iaioa aeeiiaia a Ee?anueeiio iaoeiai-aeine?aeiiio ?inoeooo? aaiaoieia??
oa ia?aeeaaiiy e?ia? ? Oe?a?inueeiio ii?eiaiio oeaio?? IIC Oe?a?ie.

IAOEIAEE EA??AIEE:

Eao?aao aea?aeaaii? i?ai?? Oe?a?ie, aeieoi? iaaee/ieo iaoe, i?ioani?,
ea??aiee a?aeae?eaiiy ii?e?a — Oe?a?inueeee ii?eiaee oeaio? —
Ee?anueeiai iaoeiai-aeine?aeiiai ?inoeoooo aaiaoieia?? oa ia?aeeaaiiy
e?ia? IIC Oe?a?ie, Iianoyiee Ieeiea THoeiiae/

IO?Oe?EI? IIIIAIOE:

Aeieoi? iaaee/ieo iaoe, i?ioani?, eaoaae?e o??o?a?? ? ii?eiai? oai?iae
Ee?anueei? iaaee/ii? aeaaeai?? i?neyaeeieiiii? ina?oe ?i. I.E. Ooieea
IIC Oe?a?ie, Eiceiaoeue Aai?a?e Iaaeiae/

Eaiaeeaeao iaaee/ieo iaoe, aeioeaio, caa?aeoaa/ eaoaae?e caaaeueii?
o??o?a?? A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?noaoo ?i. I.?.
Ie?iaiaa, AEae?aa Ieeiea Aeieo?iae/.

I?ia?aeia onoaiiaa: Oa?e?anueeee IAe? caaaeueii? ? iaa?aeeeaaeii?
o??o?a?? IIC Oe?a?ie, a?aeae?eaiiy oieo aianoac?ieia?? ? ?aai?iaoe??

Caoeno a?aeaoaeaoueny “24_” eenoiiaaea 1998 ?ieo. i 1200 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? A/aii? ?aaee E 05.600.01 i?e A?iieoeueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? ?i. I.?.Ie?iaiaa ca aae?anith:
286018, i.A?iieoey, aoe. Ie?iaiaa, 56.

C aeena?oaoe??th iiaeia iciaeiieoeny o a?ae?ioaoe? A?iieoeueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo ?i. I.?. Ie?iaiaa (i. A?iieoey,
aoe. Ie?iaiaa,56)

Aaoi?aoa?ao ?ic?neaiee “19_”aeiaoiy 1998 ?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? A/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio Iieeaeueei I.?.

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeuei?noue oaie. Iia?aoeaia a?aeiiaeaiiy ao?a/aieo oe??ieo iie?ea?a
? iniiaiiieiaeiei iaoiaeii ii?yooieo aeeooy iioa?i?eeo (I.E. Eocei ?
ni?aaao.,1982; D.I. Devies, 1983; A.N. Aeo?eaa, A.E. Ao?ieno?ia,1986; W.
Aiako, J. Iigariva, 1990; A.I. Eiceiaoe, 1992). Iaeiae aaeaeaaoia
eiiiainaoe?y ii?ooaiue aiiainoaco ia? ae??oaeueiee aieea ia ia?aa?a ?
iane?aeee ii?eiai? oai?iae (?.?. Io?acyi, I.?. Iai/aieia, 1983; A.E.
Nieiaoa ? ni?aaao., 1986; E.E. Aa?aneiiaa,1988).

Ieoaiiy iaoiaaiaco ? aoaeoeaieo iaoiae?a e?eoaaiiy ii?eiaiai oieo ?
aino?i? ii?eiai? oienai?? ua aeaeae? aei iiaiiai ae??oaiiy (?.E.
Eeaoeoe, 1986; A.O. Caeoeaa ? ni?aaao., 1986, 1988; E.E. Aa?aneiiaa,
1988; A.I. Eiceiaoe, 1992, N.A. Neana?aiei, 1996). Aaaee? ii?ee
i?eaiaeyoue aei aeeaieeo ii?ooaiue aioo??oiueiai na?aaeiaeua i?aai?cio ?
ooieoe?e aeeoo?ai aaaeeeaeo i?aai?a. I?ia?anoth/e oe? ii?ooaiiy noathoue
iaaacia/ieie aeey aeeooy, aeceaath/e caaeaaeue oai?eo a?ae ?ioieneeaoe??
? ?ioaeoe?eieo oneeaaeiaiue. Eaoaeuei?noue i?e aaaeeeo ? ae?ae aaaeeeo
ii?eao caeeoa?oueny aenieith ? eieeaa?oueny a?ae 44 aei 95% (A.O.
?oaeianeie ? ni?aaao?., 1980; Anderson of al., 1988, A.E. Aonae oa ?i.,
1992; A.I. Eiceiaoe, 1992; N.A. Neana?aiei, 1996). ?c ieo aei 60% oai?eo
aeia a noaae?? oieo ? aino?i? ii?eiai? oienai?? (A.N. Aeo?eaa, A.I.
Ao?ieno?ia, 1986; I.?. Iai/aieia, 1986).

Eiiieaenia oa?ai?y ii?eiai? oai?iae, yea aeeth/a? ?iooc?eii-o?ainooc?eio
oa?ai?th, aioea?ioeeioa?ai?th, ?ia?a?oi?e i?ioaie?co, aioeeiaaoeyioe ?
aioeaa?aaaioe, aioa?ini?aoe?th, ?ioii?, aioea?noai?ii? oa ?io?
i?aia?aoe, oe?iea canoinoaaiiy o?ce/ieo iaoiae?a e?eoaaiiy iiceoeaii
aieeaathoue ia ia?aa?a ? iane?aeee ii?eiai? oai?iae (E.I.Lowbyry, 1975;
A.G. Ian. Iillan, 1975; ?.E. Io?acyi, I.?. Iai/aieia, 1983; I.I.
Oaaei?ianueea oa ?io?, 1986; A.I. Eiceiaoeue oa ?io?, 1989; I.A. Ee?ee
oa ?io?, 1993; ?.E. Eaai oa ?io?, 1994; I.I. O?e?iiiia oa ?io?, 1994).
Aea ana ua i?iaeiaaeo? caeeoaoenue aenieith /anoioa oneeaaeiaiue
ii?eiai? oai?iae, aea o?eueee a?ae naineno iiie?a? 45-50% oai?eo (A.E.
Aonae oa ?io?, 1992; A.A. Aeaenaaa, 1993).

Nueiaiaei? a o?c?i- ? ?aoeaenioa?ai?? noi?ioaaany iiaee iai?yiie —
”a?iaaeueaai?caoe?y” (AA), yea aeicaiey? aecia/aoe, ei?aeooaaoe ?
ni?eyoe ii?iae?caoe?? ii?ooaii? ooieoe?iiaeueii-aia?aaoe/ii? ??aiiaaae
i?aai?cio, caaacia/oth/e i?e oeueiio a?iaia?aaoe/iee aiiainoac (A.A.
Iaeaoe ? ni?aaao., 1988; A.E. Ia/a?ao ? ni?aaao., 1988, A.A. Iaeaoe,
1991). Ia nueiaiaei? i?e e?eoaaii? iaia/aieo ia a?aoiao?oueny
?ioaa?aeueia ?ieue oe??iiai iie?eao, ye niaoeeo?/iiai i?aaio,
i?aaenoaaeyth/iai ia?eoa?e/io ia?aiao nenoaio, aieiae?th/iai cia/iei
?aoeaioi?iei aia?aoii, caaacia/oth/ei no?ee? eooaiii-a?noea?aeuei?
aca?iica’ycee ? aieeaath/ei ia ooieoe?? neiiaoi-aae?aiaeiai? nenoaie
(Ae.I. *a?iooa, A.I. O?ieiaa, 1982).

A e?oa?aoo?? a?aenooi? aeine?aeaeaiiy, ye? aeicaieythoue ?ice?eoe aieea
AA ia aiiainoac, ?aia?aoeai? i?ioeane, i?e?iaeith ?acenoaioi?noue,
?ioiieia?/io ?aaeoeai?noue, aoii?aeueiee ? ee?oeiiee ?ioi?oao o
iaia/aieo. Ia?niaeoeai?noue oaeiai aea/aiiy ii?eiai? iaoieia?? c
iiceoe?? oe?e?niiai i?aai?cio aaeeea.

A na?oe? aeeeaaeaiiai aeua ?ic?iaea iiaeo aaciaaeeeaiaioicieo ?
aacia/ieo iaoiae?a aieeao, ni?iiiaeieo caaacia/eoe aenieo i?io?eaeoe/io
? e?eoaaeueio aoaeoeai?noue e?eoaaiiy iaia/aieo ? aaaeeeaith iaoeiaith
i?iaeaiith, iaoiiaeth? aeooaeuei?noue aeaiiai aeine?aeaeaiiy oa eiai
iaoo.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Oaia
aeena?oaoe?? iia’ycaia c ieaiiaith iaoeiaith ?iaioith Ee?anueeiai IAe?
aaiaoieia?? oa ia?aeeaaiiy e?ia? ? ? ?acoeueoaoii IAe? “?ic?iaeoe
nenoaio e?eoaaeueieo caoiae?a, ni?yiiaaieo ia cieaeaiiy nia?oiino? oa
?iaae?aeiino? iaia/aieo ae?oae” (oeo? OeO. 527, iiia? aea?ae?a?no?aoe??
0194U017323).

Iaoa ? caaaeaiiy aeine?aeaeaiiy. Iaoa aeine?aeaeaiiy — iie?aueoe
aoaeoeai?noue e?eoaaiiy oai?eo c ii?eaie ? ii?eiaith oai?iaith ??cii?
noaiai? aaaeeino? oeyoii aeei?enoaiiy a eiiieaeni?e oa?ai?? iaia/aieo
iaoiae?a a?iaaeueaai?caoe??.

Iniiai? caaaeaiiy aeine?aeaeaiiy:

1. Aea/eoe aieea AA ia iieacieee aiiainoaco (i?e?ioee?eoeyoe?th,
niaeo?ioioiiao?e/i? oa?aeoa?enoeee e?ia? ? oe??e, aeaeo?ie?iaoe/iee
iioaioe?ae a?eo?ioeeo?a, ooieoe?? eae?e-iao???aeo ianin?a
a?eo?ioeeoa?ieo iaia?ai, eeneioii-eoaeiee neeaae).

2. Aecia/eoe aieea AA ia ??ai? aaeaioaoe?eieo ?aaeoe?e, i?e?iaeith
?acenoaioi?noue, ?ioiieia?/io ?aaeoeai?noue o iaia/aieo.

3. Anoaiiaeoe aieea AA ia ??ai? oiene/iino? ne?iaaoee e?ia?, i?e?ioei?o
? ?? ?acenoaioi?noue aei aioeaaeoa??aeueieo i?aia?ao?a;

4. ?ic?iaeoe iaoiaee a?iaia?aiae?aaiinoeee ? a?iaaeueaai?caoe?? o oai?eo
c ii?eaie;

5. Aea/eoe ee?i?/io aoaeoeai?noue a?iaaeueaai?caoe?? ? ?ic?iaeoe
?aeiiaiaeaoe?? ii ?? canoinoaaiith a eiiieaeniiio e?eoaaii? oai?eo c
ii?eaie.

Iaoeiaa iiaecia io?eiaieo ?acoeueoao?a iieyaa? a oiio, ui aia?oa a
eiiaono?ieia??:

— ?ice?eo? iaoai?cie aieeao AA ye ia ie?ai? noi?iie ii?ooaiue
aiiainoaco, oae ? ia i?aai?ci iaia/aieo a oe?eiio;

— iaa?oioiaaii canoinoaaiiy AA a aino?iio ia??iae? ii?eiai? oai?iae ?
aecia/ai? iaea?eueo aoaeoeai? iaoiaee ?? aeei?enoaiiy;

— ?ic?iaeai? iia? iaoiaee a?ioi?aco e?ea?nueeeo ?a/iaei;

— ?ic?iaeai? iaoiaee a?iaia?aiae?aaiinoeee ? ei?aeoe??
ooieoe?iiaeueii-aia?aaoe/ii? ??aiiaaae i?aai?cio ? no?eeino? eiai
aaaaoaoeaii? ia?aiai? nenoaie, ye? aeicaieythoue i?iaiaeeoe
ooieoe?iiaeueiee eiio?ieue ca a?iaeaeo?e/iith aeoeai?noth aioo??oi?o
i?aai?a iaia/aieo;

— ?ic?iaeai? iaoiaee iai?iii? a?i?aciiainii? oa?ai?? i?ae aeaiia
a?ieia?/ieie ia’?eoaie i?e ia?acao eeoa/ieea o ae?oae;

— aeiaaaeaia iiaeeea?noue ei?aeoe?? aaeaioaoe?eieo ?aaeoe?e, i?aeaeuaiiy
?ioiieia?/ii? ?aaeoeaiino? ? i?e?iaeiuei? ?acenoaioiino?;

— anoaiiaeaiee iiceoeaiee aieea AA ia niaeo?ioioiiao?e/i? oa?aeoa?enoeee
e?ia?, i?e?iaaiioee?eoeyoe?th, eeneioii-eoaeiee noai e?ia?;

— a?aee?eoee iaeei c iniiaieo iaoai?ci?a ae?? AA, yeee caeeth/a?oueny a
iiaeoethth/?e ae?? ia aeaeo?ie?iaoe/iee iioaioe?ae ? aeoeai?noue
iao???aeo ianin?a a?eo?ioeeo?a;

— aeiaaaeaia ?ioiiiiaeoethth/a ae?y AA ia aoii?aeueiee ? ee?oeiiee
?ioi?oao.

I?aeoe/ia cia/aiiy io?eiaieo ?acoeueoao?a.

1. ?ic?iaeai? iaoiaaiaoe/ii iaa?oioiaai? iaoiaee AA a eiiieaeni?e
oa?ai?? ii?eiai? oai?iae, ye? aeicaieythoue cieceoe /anoioo oneeaaeiaiue
a 1,7 ?ace, eaoaeuei?noue oai?eo c aaaeeeie ii?eaie a 2,6 ?ace, ? c
ae?ae aaaeeeie ii?eaie a 1,9 ?ac.

2. ?ic?iaeai? iaoiaee ei?aeoe?? ia?aa?ao ?aiiaiai i?ioeano oeyoii
niieo/aiiy iiaeoethth/i? ae?? AA c aie?eaoe?eiith ni?aoe??th, ye?
aeicaieythoue nei?ioeoe no?iee caaeeaeaiiy iiaa?oiaaeo ii?e?a IIIA
noaiai? ia 5 aei?a, i?iaiaeeoe ia?o? aooiaea?iiieanoeee ia 7-10 aei?a
?ai?oa, caaacia/eoe iaeoaeaiiy oai?eo i?e ii?eao IIIA-IV noaiai? ia
12,1-12,9 aei?a oaeaeoa.

3. ?ic?iaeaiee niin?a a?ioi?aco e?ea?nueeeo ?a/iaei aeicaiey? nei?ioeoe
ia 8 aei?a ia??iae e?eoaaiiy caiaeaiiy eaaaiue o iaia/aieo ae?oae, a AA
i?e ia?acao eeoa/ieea o ae?oae a?aeiiaeth? eiai ia?enoaeueoeeo.

4. ?ic?iaeaia nenoaia ooieoe?iiaeueiiai eiio?ieth ca nenoaiiei
aiiainoacii ? aoaeoeai?noth eiiieaenii? oa?ai??.

5. ?acoeueoaoe aeine?aeaeaiiy ai?iaaaeaeai? a e?eoaaeueio i?aeoeeo
Oe?a?inueeiai ii?eiaiai oeaio?o (i. Ee?a), A?iieoeueeiai,
Oa?iii?euenueeiai iaeanieo, Euea?anueeiai aeeoy/iai iaeaniiai ii?eiaeo
a?aeae?eaiue.

Iniaenoee aianie caeiaoaa/a. Aaoi?ii ?ic?iaeai? i?ia?aia ? iaoiaee AA o
iaia/aieo ??ciiai a?eo ? ??cii? aaaeeino? oa?i?/ieo o?aaeaiue. Aecia/aia
aoaeoeai?noue AA, ?? aieea ia aiiainoac, ianiaoeeo?/io ?acenoaioi?noue,
aoii?aeueiee ? ee?oeiiee ?ioi?oao. Aaoi?ii i?ie?eiaaii 90% ianoaaeaieo
oai?eo, aeeiiaii a?eueoa 90% iia?aoeaieo ao?o/aiue. Aeeaae a
aenia?eiaioaeuei? aeine?aeaeaiiy neeaaea? a?ey 60%. A noi?nii
iioae?eiaaieo ?iaioao c ae.i.i. A.A. Iaeaoeii aaoi?o iaeaaeeoue 70%
?aeae ? ?ic?iaie.

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??. Iniiai? iieiaeaiiy aeena?oaoe??
aeeeaaeai? oa iaaiai?ai? ia VI ?anioae?eainuee?e eiioa?aioe?? ii
i?iaeai? “Ii?ee” (Oa?e?a, 1988), ia’?aeiaiiio can?aeaii? i?iaeaiieo
eii?n?e IIC Oe?a?ie (Ee?a, 1993), I(XVI)c’?cae? o??o?a?a Oe?a?ie
(Euea?a, 1994), ?anioae?eainuee?e eiioa?aioe?? “Aeooaeuei? i?iaeaie
iaaeeoeeie” (A?iieoey, 1996), iaoeiai-i?aeoe/i?e eiioa?aioe??
“Aeooaeuei? ieoaiiy o??o?a??” (Ee?a-Oiaeueieoeueeee-A?iieoey, 1997),
?anioae?eainueeeo nai?ia?ao caa?aeoth/eo ii?eiaeie a?aeae?eaiiyie
Oe?a?ie (??aia, 1990; Iaie??a, 1996; AEeoiie?, 1997), iaoeiaiio
oiaa?enoa? o??o?a?a (A?iieoey, 1991, 1997).

Ioae?eaoe??. Ii oai? aeena?oaoe?? iioae?eiaaii 20 iaoeiaeo ?ia?o, ?c ieo
iaeia iiiia?ao?y, iaeei ?icae?e a iiiia?ao??, ?io? ?iaioe iioae?eiaai? a
iaoa??aeao c’?cae?a, eiioa?aioe?e, neiiic?oi?a. Io?eiaia aaoi?nueea
na?aeioeoai ia aeiao?ae, aeaeaii aea? iaoiaee/i? ?aeiiaiaeaoe??,
io?eiaiee aeeieii II nooi?ith ? n??aia iaaeaeue AAeIA ONN? ii
?ic?iaethaai?e oaiaoeoe?.

No?oeoo?a aeena?oaoe??. ?iaioa neeaaea?oueny c anooio, i’yoe ?icae?e?a,
aeniiae?a, nieneo aeei?enoaii? e?oa?aoo?e, aeiaeaoe?a. Aeena?oaoe?y
aeeeaaeaia ia 184 noi??ieao iaoeiiieno, (147 noi??iie oaenoo).
?ethno?iaaia 28 oaaeeoeyie ? 20 iaethieaie,(37 noi??iie). Aeac?aiee
e?oa?aoo?e aeeth/a? 396 aeaea?ae.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee oa iaoiaee

?iaioa aaco?oueny ia niinoa?aaeai? iaae 360 iaia/aieie a?eii a?ae oanoe
i?nyoe?a aei 86 ?ie?a, ui ciaoiaeeeenue ia e?eoaaii? a A?iieoeueeiio
iaeaniiio ii?eiaiio a?aeae?eaii? c 1989 ii 1996 ??e, na?aae yeeo 186
oai?eo — (51,66%) neeaee iniiaio a?oio, i?e e?eoaaii? yeeo i?iaiaeeee
a?iaaeueaai?caoe?th ii ?ic?iaeaieo iaie iaoiaeeeao; 174 oai?eo (48,34%),
yeei i?iaiaeeee caaaeueiii?eeiyoa e?eoaaiiy, neeaee eiio?ieueio a?oio.
Ae?oao eiio?ieueio a?oio neeaee 96 i?aeoe/ii caei?iaeo in?a a?eii a?ae
18 aei 50 ?ie?a, o yeeo aeine?aeaeaiee ?yae iieaciee?a, aeei?enoaieo
aeey aecia/aiiy aieeao a?iaaeueaai?caoe?? ia aiiainoac i?e ii?iaeuei?e
?aaeoe?? i?aai?cio.

Na?aae oai?eo, yeeo niinoa??aaee — /ieia?e?a aoei 189 (52,5%) ? ae?iie
171 (47,5%). I?e oeueiio a iniiai?e a?oi? /ieia?e?a ? ae?iie aoei
ii??aio (ii 93 oai?eo), a eiio?ieuei?e a?oi? /ieia?e?a aoei 96 (55,17%)
? 78 ae?iie (44,83%). Ae?oae a?eii aei 14 ?ie?a aoei 158 (43,89%),
aei?ineeo a?eii a?ae 21 aei 60 ?ie?a — 143 (39,72%). ?acii c oei na?aae
oai?eo aoei 30 in?a iioeeiai ? noa?a/iai a?eo (8,83%). *eiieeaie
oa?i?/ieo o?aaeaiue a 185 aeiaaeeao (51,38%) aoea aa?y/a ??aeeia ? ia?,
a 117 (32,5%) — iieoi’y, a 37 (10,28%) — aa?y/? i?aaeiaoe ? ?icieaaeaiee
iaoae, a 16 (4,44%) — aeaeo?io?aaia, a 5 (1,38%) — eeneioe ? eoae.
O?aaeaiiy aeeoaeueieo oeyo?a niinoa??aaeinue a 45 aeiaaeeao (12,5%).

Caaaeueia ieiua oa?i?/ieo o?aaeaiue ianoaaeaieo oai?eo aoea a?ae 6-8%
aei 75% iiaa?oi? o?ea. 168 oai?eo (46,64%) iaee ii?ee ia ieiu? a?eueoa
30% iiaa?oi? o?ea, a oiio /ene? o 90 oai?eo (26,0%) aiie aoee ia ieiu?
aeua 50% iiaa?oi? o?ea. Oai?? iaee ye iiaa?oiaa? oae ? aeeaie? oa?i?/i?
o?aaeaiiy. C ieo 140 (38,89%) iaee eaaeo noai?iue o?aaeaiiy ? 95
(26,39%) na?aaeith. A oie aea /an 125 iaia/aieo (34,72%) iaee aaaeeo ?
ae?ae aaaeeo noai?iue oa?i?/ieo o?aaeaiue.

An?i oai?ei iaio a?oi i?iaiaeeeanue ?aeaioe/ia caaaeueia ? i?noeaaa
oa?ai?y, yea aeeth/aea aacenio ?iooc?eii-o?ainooc?eio oa?ai?th,
aioea?ioeee, aetheiei?oeei?aee, ?ia?a?oi?e i?ioaie?co, noa?i?aei? ?
ianoa?i?aei? i?ioecaiaeuei? i?aia?aoe, aioeaa?aaaioe, aioeeiaaoeyioe,
ianeaio ?ioiioa?ai?th ? ?io? caaaeueiii?eeiyo? i?aia?aoe (A.I.
Eiceiaoeue, 1992, N.A. Neana?aiei, 1996).

I?noeaaa e?eoaaiiy ii?e?a i?iaiaeeeinue cae?eoei iaoiaeii c
aeei?enoaiiyi ni?aaioo AOAI — “Aei?i?i”, yeee o oai?eo iniiaii? a?oie a
ia?oo iieiaeio aeiae aeeiioaaa ?ieue aeaeo?iaeo-aeiii?o aeaeo?ii?a aeey
i?iaaaeaiiy AA, a ae?oao iieiaeio aeiae aeeiioaaa ?ieue aie?eaoe?eiiai
ni?aaioo. A eiio?ieuei?e a?oi? oeth iia’yceo iaeeaaeaee ia ?aie o?eueee
c oe?eeth aie?eaoe?eii? ni?aoe??.

I?e i?aeaioiaoe? aeeaieeo ii?e?a aei aooiieanoeee i?iaiaeeee ?aii?
iae?aeoii?? (ia 5-6 aeiao), aai c 9-10 aeiae aeeiioaaee iiaoaii?
aace?iai? iae?aeoii??. A?aioethth/? ?aie cae?eaaee
aooiaea?iio?ainieaioaoaie ii eiioo?o, aeei?enoiaoth/e i?e aeao?oeeo?
oe??ieo ?ano?n?a n?o/ao? o?ainieaioaoe c eiao?oe??ioii ca?eueoaiiy 1:2
aai 1:4.

Anueiai aoei iia?iaaii 250 oai?eo (69,44%), yeei aoea i?iaaaeaia 721
iia?aoe?y, iniiaieie c yeeo aoee aooiaea?iiieanoeee (678-94,0%).
Na?aaeiy ieiua a?aeiiaeaiiai oe??iiai iie?eao neeaaeaea 10-12% iiaa?oi?
o?ea. O eiaeiiai oai?iai a na?aaeiueiio aeeiiaii 2,7 aooiaea?iiieanoeee.

A ?iaio? aeei?enoai? ee?i?/i?, aaiaoieia?/i?, a?io?i?/i?, a?io?ce/i?,
i?e?ia?ieia?/i?, ?ioiieia?/i? ? ii?oieia?/i? iaoiaee aeine?aeaeaiiy.

Aieea o?eaaei? a?iaaeueaai?caoe?? ia noai i?aeeaaeeo i?ae aeaeo?iaeaie
oeaiei aea/aeinue ia 25-oe ieoao e?i?? N57AI/6 ianith 20-26 a. ? 36
a?eeo iae?i?eieo uo??a ianith 210-270 a. ii ?ic?iaeai?e iaie iaoiaeeoe?
(A.A. Iaeaoe ? ni?aaao., 1990). Na??ei? c??ce i?aia?ao?a oa?aoaaee
aaiaoienee?i-aiceiii (I.Aieeia, TH.E. Aeaoeueeee, 1932). Aeine?aeaeaiiy
aeeiiaii ia aac? ?inoeoooo i?iaeai iieieia?? ?i. ?.A.Eaaaoeueeiai AI
ONN? ?acii c no.i.n., eaiae. a?ie. iaoe A.A. Ne?iiyoieeiaei.

Aeaeo?ioi?aoe/io ?ooeea?noue a?eo?ioeeo?a (AO?A) — oaeaee?noue ?o
ia?ai?uaiiy a aeaeo?iiaai?oiiio iie? aecia/aee ia eiiieaeniiio
onoaoeoaaii? “Ia?iieaaio-2” o??ie “Ea?e-Oeaenn-Eaia” (I?ia//eia) ii
iaoiaeo A.A. Aa?iiaiei (1987). Aeine?aeaeaiiy aeeiiaii ia aac?
Aaoee?nueeiai aea?aeaaiiai oi?aa?neoaoo ?acii c aeieo. a?ieia. iaoe A.A.
Aa?iiaiei.

Noai i?e?ioee?eoeyoe?? aea/aee ii a?ii?e?ineii?? eii’thieoeae iea c
canoinoaaiiyi oioiu?eueiai? eaiie o??ie “Oeaen” ii a?aeiiei e?eoa??yi
(E.O. Iaeay ? ni?aaao., 1977).

Aaeoa??ioeeaeio ? aaeoa??inoaoe/io ae?th aea/aee ia eoeueoo?ao
noao?eieieo, iii?uaieo ia iiaeeai? na?aaeiaeua a oiiaao oa?iinoaoo, i?e
oaiia?aoo?? 360 (I.I. Ae?aa?, 1982). Aeine?aeaeaiiy aeeiiaii ia aac?
A?iieoeueeiai iaaee/iiai oi?aa?neoaoo ?i. I.?. Ie?iaiaa ?acii c eaiae.
a?ie. iaoe A.O. Iaeaoe. ?ioaa?aeueio ioe?ieo eaeeia?aie i?iaiaeeee ii
E.X. Aa?eaa? ? ni?aaao., (1979), ? ii iayaiino? ??cieo oei?a eaeeioeeo?a
oa ?o ni?aa?aeiioaiith iii?ae niaith aecia/aee
aaeaioaoe?eii-i?enoinoaaeuei? ?aaeoe??. I?e oeueiio ?aaeoe?? o?aioaaiiy
? aeoeaaoe?? a?aeiineee aei o?c?ieia?/ieo, a ?aaeoe?th aino?iai no?ano
aei iaoieia?/ieo.

Niaeo?ioioiiao?e/i? oa?aeoa?enoeee e?ia? ? a?ieia?/ieo oeaiei aea/aeenue
ia aaaaoiooieoe?iiaeueiiio niaeo?ioioiiao?? NO-16 ? NO-46 ii iaoiaeeoe?
A.N. Niie?inueeiai ? ni?aaao. (1991). Aeine?aeaeaiiy aeeiiaii ?acii c
aeieo. iaae. iaoe A.A. Iaeaoeii.

Aeine?aeaeaiiy ?ioi?oaoo o oai?eo, ui niinoa??aaeenue, i?iaiaeeee ii
eaieao. Aeey ioe?iee ee?oeiii? eaiee ?ioi?oaoo aea/aeenue ia?aiao?e
e?eueeino? e?ioioeeo?a (A.A. Eino, 1975), A-?IE, aeoeai? A-?IE ? AAN-?IE
e?ioioeeo?a, e?euee?noue O-oaeia??a ? O-noi?ani??a, a oaeiae
ni?aa?aeiioaiiy O-oaeia??a aei O-noi?ani??a (A.A. Iaiueoeeia ? ni?aaao.,
1987; A.O. *a?iooaiei, E.N. Eiainiaa, 1981).

Aeey aea/aiiy noaio aoii?aeueii? eaiee ?ioi?oaoo aecia/aee e?euee?noue
?ioiiaeiaoe?i?a eeano A,I,G, a ne?iaaooe? e?ia? iioa?i?eeo ii Iancini at
al. (1969) c iiiiniaoeeo?/ieie aioene?iaaoeaie i?ioe ?ioiiaeiaoe?i?a
ethaeeie, aeaioiaeaieo a Ai?e?anueeiio IAe? ai?aeai?ieia?? ?
i?e?ia?ieia?? (?in?y). Aeei?enoiaoaaee aaeoi-aaa? o??ie “Difco” (NOA).
?ioiieia?/ia ?aaeoeai?noue i?aai?cio aecia/aeanue ii iaoiaeo A.E. Iae?y
? ni?aaao., aao. na?ae. ?1082399 (1982). Aeine?aeaeaiiy aeeiiaii ia aac?
A?iieoeueeiai iaaee/iiai oi?aa?neoaoo ?i. I.?. Ie?iaiaa ?acii c eaiae.
a?ie. iaoe A.O. Iaeaoe.

Aeey ioe?iee i?e?iaeiuei? ?acenoaioiino? i?aai?cio iaia/aieo aea/aeenue
?yae iieaciee?a — aaeoa?eoeeaeia aeoeai?noue ne?iaaoee e?ia? ii A.O.
*a?iooaiei, E.N. Eiainiaie (1978), oeo? eiiie?iaioo ii iaoiaeo Eaaioa,
1968 (A.I. Oeyoia ? ni?aaao., 1985), oaaioeeoa?ia aeoeai?noue
eaeeioeeo?a ii A.A. Iaiueoeeiao, 1987.

Eiioeaio?aoe?th iieaeoe na?aaeiuei? iieaeoey?ii? iane a ne?iaaooe? e?ia?
aecia/aee ii I.E. Aaa?e?eyio ? ni?aaao. (1985).

Eeneioii-eoaeiee noai e?ia? aecia/aee ia aiae?caoi?? ?II IE-2 (Aeai?y)
ii iaoiaeo “Ano?oia” (A.A. Aaiaeoeueeee, 1988; E.I. *aieee ? ni?aaao.,
1988).

?acoeueoaoe aeine?aeaeaiiy ia?iaeyeenue iaoiaeeeaie aa??aoe?eii?
noaoenoeee c aecia/aiiyi aeinoia??iino? io?eiaieo ?acoeueoao?a
(I.E.Aaeaiueeee, 1959, I.?. Iinoiaie, 1954; I.I. Naiieeia, 1970). I?e
cia/i?e ?iaeea?aeoaeuei?e ??cieoe? aeei?enoiaoaaee iaoiaee
iaia?aiao?e/ii? noaoenoeee (A.A. Aea?aa’yiei ? ni?aaao., 1976).

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy

Ca aeaieie aenia?eiaioaeueieo aeine?aeaeaiue ia oaa?eiao iaie
anoaiiaeaii, ui o?eaaea AA ia i?ioyc? 21 aeiy ii 6 aiaeei uiaeaiii ia
aeceaa? aoaeue-yeeo iaoieia?/ieo ci?i a oeaieiao, ye? aeiaaee /an
ia?aaoaaee i?ae aeaeo?iaeii-aeiii?ii ? aeoeaioi?ii aeaeo?ii?a.

Iaie aia?oa iieacaiee iiceoeaiee aieea AA ia ?yae iieaciee?a aiiainoaco
(niaeo?ioioiiao?e/i? oa?aeoa?enoeee e?ia?, aeaeo?ioi?aoe/io ?ooeea?noue
a?eo?ioeeo?a, i?e?ioee?eoeyoe?th, eeneioii-eoaeiee noai, ??aaiue
na?aaei?o iieaeoe, ?ioiieiiiaoaioi? ee?oeie e?ia?, ??ai? aaeaioaoe?eieo
?aaeoe?e, ianiaoeeo?/io ?acenoaioi?noue, aoii?aeueiee ? ee?oeiiee
?ioi?oao).

Anoaiiaeaii, ui o iaia/aieo a noaae?? aino?i? ii?eiai? oienai?? ia?
i?noea ??cea cieaeaiiy AO? a?eo?ioeeo?a ia?eoa?e/ii? e?ia? (aei
0,74-0,76 o 10-8 i2/n.o. i?e ii?i? 1,10-1.24 o 10-8 i2/n.o., ?<0,001). I?ney i?iaaaeaiiy AA ii caaaeueiinoeioethth/?e iaoiaeeoe? ia i?ioyc? 40 oa. o 18 oai?eo c ii?eaie a?ae 20 aei 90% iiaa?oi? o?ea e?eaa ?iciiae?eo a?eo?ioeeo?a ii ?o AO? ci?uaeanue ai?aai a?eueo, ye ia aea? n?aie a?ae aeo?aeiiai ??aiy iniiaii? iane ia?eoa?e/ii? e?ia? ? neeaea 0,85 o 10-8 i2 ± 0,06 i2/n.o. (?<0,001), ui aoei aeua ia 13% a?ae aeo?aeiiai ??aith. A oie aea /an o oai?eo eiio?ieueii? a?oie AO? a?eo?ioeeo?a cieaeoaaeanue ia 2,6%, neeaaeath/e 0,74 o 10-8 ± 0,01 i2/n.o. (?<0,01). Iiae?aia ae?y AA na?ae/eoue i?i aeoeaaoe?th iao??e-eae??aeo ianin?a a?eo?ioeeoa?ieo iaia?ai. I?aeoaa?aeaeaiiyi oeueiai ? oie oaeo, ui i?ney aaaaeaiiy no?ioaioeio (10-5 I), yeee ? ?ia?a?oi?ii iao??e-eae??ai? AOO-ace, a i?iao e?ia? in vitro, yeo iiia?aaeiuei i?aeaeaee AA, i?ioiaeeei cieaeaiiy AO? a?eo?ioeeo?a c 0,85 o 10-8 ± 0,06 i2/ n.o. aei 0,81 o 10-8 ± 0,01 i2/n.o. (?<0,01). Iaeii?aciaa caaaeueiinoeioethth/a AA ia i?ioyc? iaei??? aiaeeie ia? ae?aaeaiee iiceoeaiee aieea ia i?e?iaaiioee?eoeyoe?th eii’thieoeae i/ae. Oae o 25 oai?eo iniiaii? a?oie c ii?eaie II-III AA no. ia ieiu? a?ae 20 aei 60% iiaa?oi? o?ea iieacieee eii’thieoeaaeueii? i?e?iaaiioee?eoeyoe??, ii aeaieo a?ii?e?ineii??, aeinoia??ii iie?auoaaeenue ia 51,7% a?ae aeo?aeiiai ??aiy (c 22,4±0,6 aei 10,5±0,5 aae?a ii E. Iae?e - ?<0,001). A oie aea /an ye a eiio?ieuei?e a?oi? oai?eo (14 /ieia?e) aiie i?aeoe/ii caeeoaeenue ia iaeiiio ??ai? (21,8±0,6 aae?a). I?ae aieeaii AA ci?iththoueny ? niaeo?ioioiiao?e/i? oa?aeoa?enoeee e?ia?, aea/ai? iaie o 65 oai?eo c ii?eaie II-III AA no. ia ieiu? a?ae 5% aei 35% iiaa?oi? o?ea. Iniaeeai ?ioi?iaoeaieie, ii iaoei aeaiei, ? ae?aiacii oaeeue a?ae 500 aei 600 ii, a yeiio iaea?eueo aeoeaii iiaeeiathoueny ieeneai?, aeenioe?eiaai? aai c?oeiiaai? oi?ie aaiiaeia?io (ien?-ea?aien?-aaiiaeia?io). Aiae?c aaee/ei aeaieo niaeo??a iiaeeiaiiy ieacie 96 aei?ineeo i?aeoe/ii caei?iaeo ethaeae-aeiii??a e?ia? ??cieo a?oi c ?acon-iiceoeaiei ? ?acon-iaaaoeaiei oaeoi?ii iieacaa, ui i?e a?aenooiino? oi?iaiieo aeaiaio?a ieacia e?ia? aieiae?? cia/iith iiaeeiaeueiith cae?ai?noth a iaeanoyo 300-500 ii ? 900-1200 ii, i?i?iaeueia ae iiaeeiaeueia cae?ai?noue a?aecia/a?oueny ia aeiaaeei? oaeeue a?ae 600 aei 900 ii. Aeiaaaeaii, ui niaeo?ioioiiao?e/i? oa?aeoa?enoeee ne?iaaoee e?ia? ci?iththoueny a caeaaeiino? a?ae oa?aeoa?o AA. I?iaaaeaiiy iicaeiaaeiuei? AA o 23 iaia/aieo aeceaaei ci?ie a ae?eyioe? niaeo?o iiaeeiaiiy 500-600 ii. A?aecia/a?oueny ??ceee ??no aeaio i?e?a: 540 ii (Ia,Ia) ? 570 ii (I8I3IaI2, Ia/NI4), ui na?ae/eei i?i iane/aiiy oeaiei eeniai, ?inoii iecueeinieiiaeo noai?a aaiiaeia?io, aecaaieo ca’ycoaaiiyi eeniaaiai e?aaiaeo. A a?oi? oai?eo (20 /ieia?e), eiee a ciio AA aoea aeeth/aia ia/?iea, oa?aeoa?iei aeyaeeenue ae?eyiee iiaeeiaiiy 300-400 ii ? 500-600 ii. Ia?oa ?c ieo na?ae/eea i?i iayai?noue ae?eiceae?a, ae?oaa - i?i eiioeaio?aoe?ei? eieeaaiiy aaiiaeia?io. A oie aea /an i?iaaaeaiiy AA i?ae /an iia?aoe?e (22 iaia/aieo) ? ia?aa’ycie c canoinoaaiiyi ia?eico i?eaiaeeoue aei ciaioaiiy i?e?a a niaeo?? iiaeeiaiiy 500-600 ii. Oea eiia??ii a?aeia?aaea? oie oaeo, ui a ia??iae i?iaaaeaiiy ia?eico c aeei?enoaiiyi ia?eioe/ieo ?a/iaei ? a iaeaeeae/ee i?neyiia?aoe?eiee ia??iae (30-40 oa). ?icaeaa?oueny a?iien?y, yea ca’ycaia ye ? c ci?iith noaio aaiaoiaeueaaiey?iiai aa?’??o, oae ? ooieoe?yie na?oeaai-noaeeiii? nenoaie. AA ae?eyiee aeei/eiai? caeice, iaaiaee ca?eueoo? iiaeeiaeueio aeoeai?noue o aeacaiiio ?ioa?aae? aeiaaeeie oaeeue aei cia/aiue 0,7-1,0 I ni-1. Iiae?ai? ci?ie iiaeia iiynieoe iane/aiiyi oeaiei eeniai, noaa?e?caoe??th ?aaoeyoi?ieo i?ioean?a a oeaieiao, a oaeiae noeioeyoe??th ooieoe?e e?iaiiinii? nenoaie. I?iaaaeai? niaeo?ioioiiao?e/i? aeine?aeaeaiiy iieacothoue, ui iaeiei c iaoai?ci?a ae?? AA ? iie?auaiiy “oeaieiiiai aeeoaiiy”, iane/aiiy oeaiei eeniai, ??no iecueeinieiiaeo noai?a aaiiaeia?io, aecaaieo ca’ycoaaiiyi eeniaaiai e?aaiaeo. Ii?yae c iie?auaiiyi i?e?ioee?eoeyoe??, AO? a?eo?ioeeo?a i?ney AA o iaia/aieo a?aei?/aeenue iaai? c?ooaiiy iieaciee?a eeneioii-a?aeiiaiiai noaio, aea/ai? iaie o 15 iioa?i?eeo c ii?eaie II-IIIA-IIIA no. a?ae 20 aei 70% iiaa?oi? o?ea. O iioa?i?eeo a aino?iio ia??iae? ii?eiai? oai?iae a?aei?/a?oueny noaeiiiainiaaia aai aeaeiiiainiaaia oi?ia iaoaaie?/iiai aeeaeico (?I aei??aith? 7,54±0,1) ? cia/ia oeaieiia a?iien?y, ca’ycaia c iecueeei ??aiai ?I2 e?ia? (55,52±2,23). Iaeii?aciaa aioo??oiueiaaiia AA ia i?ioyc? aiaeeie i?eaiaeeea aei ciaioaiiy aeeaeico (?I noaaaei 7,51±0,008 - ?<0,05) ? i?aeaeuaiiy ia?oe?aeueiiai oeneo eenith a e?ia? (57,79±2,46 - ?<0,01). ?io? iieacieee eeneioii-eoaeiiai noaio nooo?ai ia ci?ithaaeenue. Aeineoue iieacieie aoee c?ooaiiy a a?aeiioaii? ??aiy na?aaei?o iieaeoe a ne?iaaooe? e?ia? i?ney i?iaaaeaiiy aioo??oiueiaaiii? AA, aea/ai? iaie o 15 iaia/aieo c ii?eaie a?ae 20 aei 45% iiaa?oi? o?ea II-IIIA-IIIA noaiai?. Aei i?iaaaeaiiy AA ??aaiue na?aaei?o iieaeoe aoa 0,380±0,06 iae.ii.u., ui na?ae/eei i?i ae?aaeaio ?ioieneeaoe?th. I?ney i?iaaaeaiiy naaino AA ?o ??aaiue aeinoia??ii cieaeoaaany aei 0,290±0,02 iae.ii.u (?<0,001), ui na?ae/eei i?i aeac?ioieneeaoe?eio ae?th AA i?e aaaeeeo oa?i?/ieo o?aaeaiiyo. Cieaeaiiy ??aith ?ioieneeaoe?? i?ae aieeaii AA iaaoaeue iiaeia iiynieoe iie?auaiiyi i?e?ioee?eoeyoe??. Iaeiae ia iiaeia ia a?aoiaoaaoe ? oie oaeo, ui canoinoaaiiy AA i?eaiaeeoue aei i?aeaeuaiiy /ooeeaino? aini?oaeueieo ? noaiaea?oieo ooai?a noao?eieie?a aei aioea?ioee?a ? iaio ae?aaeaiiio ?o ?inoo, oei naiei aei cieaeaiiy ??aiy i?e?iaii? ?ioieneeaoe??. I?iaaaeai? iaie aeine?aeaeaiiy in vitro c aini?oaeueieie ooaiaie noao?eieie?a na?ae/aoue, ui i?e ae?? neaaeeo aaeueaai?/ieo no?oi?a (aei 40 ieA) ia i?ioyc? 6 aiaeei ia eiio?ieueieo iiaeeaieo na?aaeiaeuao c?inoaei a?ae 12 aei 18 oeny/ eieii?e noao?eieie?a, ia aeine?aeieo - a?ae 1,5 aei 4 oeny/. *a?ac 12 aiaeei e?euee?noue eieii?e i?e?ia?a a iniiai?e a?oi? aoei iaioei, i?ae a eiio?ieuei?e na??? aeine?aeaeaiue a?ae 8 aei 37 ?ac. *a?ac 24 aiaeeie ??cieoey a e?eueeino? i?e?ii?aai?ci?a a iniiaieo ? eiio?ieueieo aeine?aeaeaiiyo neeaea a?ae 3,5 aei 8,8 ?ac. ?aeaioe/i? aeai? aoee io?eiai? ? i?e aeine?aeaeaiiyo aieeao AA ia noaiaea?oi? ooaie noao?eieie?a ? 1,3,5,6,13 ? 209. Aaaeeeai, ui i?ney ae?? neaaeeie aaeueaai?/ieie no?oiaie ia i?e?ioei?o /ooeea?noue inoaiiuei? aei aioea?ioee?a ? aioenaioee?a cia/ii c?inoaea. Oae, /a?ac 24 aiaeeie aiia a aeine?aei?e na??? c?inoaea, ye i?i?ioi a aeaa ?ace ii a?aeiioaiith aei aini?oaeueieo ooai?a noao?eieiea i?e ae?? aeaeaiaoieneio: 0,9-31,2 iae/ie aei AA ? 0,45 iae/ie i?ney 24 aiaeei AA. Aiaeia?/ia ea?oeia a?aei?/aeanue i?ney ae?? neaaeeo aaeueaai?/ieo no?oi?a ? ia eaai?aoi?i? ooaie noao?eieie?a ? 1,3,5,9,209, ye? aeioee i?e eiioeaio?aoe?? aeaeaiaoieneio 0,45 iae/ie. Oi/a ieoaiiy i?i iaoai?cie aaeoa?eoeeaeii? ? aaeoa??inoaoe/ii? ae?? neaaeeo aaeueaai?/ieo no?oi?a ia ooaie noao?eieie?a caeeoathoueny a?aee?eoeie, ?acii c oei aeyaeaiee oaeo i?aeaeuaiiy /ooeeaino? i?e?ioei?e aei aioea?ioee?a ? o?i?ioa?aiaaoe/ieo i?aia?ao?a i?ae aieeaii AA, ye iaoiae, iiaea aooe ?aeiiaiaeiaaiee aeey aeeth/aiiy a eiiieaenio oa?ai?th ai?eii-caiaeueieo caoai?thaaiue ? i?io?eaeoeee oneeaaeiaiue ye a eiiaono?ieia??, oae ? a o??o?a?? acaaae?. Ii?yae c iacaaiei aeua iiceoeaiei aieeaii AA ia ieceo oaeoi??a aiiainoaco, iaie aoei anoaiiaeaii, ui i?iaaaeaiiy ?? nooo?ai a?aeia?aaeo?oueny ia ??aiyo ? oa?aeoa?? aaeaioaoe?eieo ?aaeoe?e, ye? ? ianiaoeeo?/iith iniiaith iaoieia?/iiai i?ioeano, a?aeia?aaeothoue aioeno?ania? iaoai?cie, iia’ycai? c ii?iae?caoe??th ooieoe?iiaeueii-aia?aaoe/ii? ??aiiaaae i?aai?cio, no?eeino? eiai aaaaoaoeaii? ia?aiai? nenoaie. I?e aea/aii? oa?aeoa?o aaeaioaoe?eieo ?aaeoe?e o 149 iaia/aieo (99 iniiaii? a?oie oa 50 eiio?ieueii? a?oie) iaie aoei anoaiiaeaii, ui o an?o a?oiao oai?eo a?aei?/a?oueny ?aeaioe/iee iai?yiie aaeaioaoe?eieo ?aaeoe?e i?e i?iaaaeaii? AA ia i?ioyc? 3-o oeaei?a. I?e oeueiio ??cei ciaioo?oueny e?euee?noue oai?eo c ?aaeoe??th aino?iai no?ano (c 30,3% o eaaei iaia/aieo, c 63,7% o iaia/aieo na?aaeiuei? noai?i? aaaeeino? ? c 78,0% o oai?eo c aaaeeeie ii?eaie aei 9,3-9,6% o oai?eo oeeo a?oi) ? c?inoa? e?euee?noue oai?eo c ?aaeoe?yie o?aioaaiiy ? aeoeaaoe?? (ianiaoeeo?/ii? iniiae ii?ie) - aei 90%. Iaeiae ?aaeoe?y aino?iai no?ano o oai?eo c eaaeeie ii?eaie a eiio?ieuei?e a?oi? aoea a o?e ?ace /ano?oith (9,3% a iniiai?e ? 27,8% a eiio?ieuei?e a?oi?), o oai?eo c ii?eaie na?aaeiuei? aaaeeino? ? aaaeeeie ii?eaie a?aei?/aeinue a?aeiia?aeii a 5,5 ? 6,5 ?ac?a /ano?oa (50,1% ? 60,6% oai?eo a?aeiia?aeii i?ioe 9,6% a iniiaieo a?oiao) ii??aiyii c iniiaiith a?oiith. Ia iiaeia ia a?aecia/eoe oaeiae, ui i?e ae?ae aaaeeeo ii?eao a aeiaeiiai ?c iaia/aieo aac i?iaaaeaiiy AA ia a?aei?/aeinue ci?ie aaeaioaoe?eieo ?aaeoe?e, ye? o an?o oai?eo eiio?ieueii? a?oie aanue ia??iae aeine?aeaeaiue oa?aeoa?ecoaaeenue ye ?aaeoe?? aino?iai no?ano. I?ae aieeaii AA c?inoaa ? ??aaiue aaeaioaoe?eieo ?aaeoe?e o an?o a?oiao oai?eo. Cie?aia o oai?eo c eaaeeie ii?eaie ??ai? ?aaeoe?e o?aioaaiiy ? aaeaioaoe?? c?inoaee c 30,37±0,01 ? 0,80±0,06 a?aeiia?aeii (3-y aeiaa) aei 0,40±0,009 ? 0,90±0,02 ia 21 aeiao (?<0,05). O oai?eo c ii?eaie na?aaeiuei? noai?i? aaaeeino? ? aaaeeeie ii?eaie ??ai? ?aaeoe?? o?aioaaiiy i?aeaeuoaaeenue a?aeiia?aeii c 0,36±0,01 ? 0,40±0,05 (ia 3-th aeiao) aei 0,40±0,01 ? 0,46±0,01 (ia 21-o aeiao). ?aaeoe?? aeoeaaoe?? ca oeae ia??iae a?aeiia?aeii aeinoia??ii c?inoaee c 0,50±0,08 ? 0,40±0,02 aei 0,80±0,07 ? 0,80±0,1. Oa?aeoa?ii, ui o ia?oeo o?ueio a?oi oai?eo a?aei?/aeinue oaeiae i?aeaeuaiiy ??ai?a ?aaeoe?e o?aioaaiiy ? aaeaioaoe?eieo ?aaeoe?e, aea aoei aanue ia??iae niinoa?aaeaiue aeinoia??ii ieae/ei, i?ae o oai?eo iniiaii? a?oie. Ui noino?oueny oai?eo c ae?ae aaaeeeie ii?eaie, oi o iioa?i?eeo eiio?ieueii? a?oie ia o?eueee ia a?aei?/aeinue ?aaeoe?e o?aioaaiiy ? aeoeaaoe?? aea ? cieaeoaaany ??aaiue ?aaeoe?? aino?iai no?ano. I?e i?iaaaeaii? AA o oe??? a?oie iioa?i?eeo aaea c 3-? aeiae niinoa??aaeanue ?aaeoe?y aeoeaaoe?? ? ?aaeoe?y o?aioaaiiy c aeinyaiaiiyi ??aiy aeecueeiai ??aiyi o oai?eo ia?oeo o?ueio a?oi (0,30±0,01 ?aaeoe?y o?aioaaiiy ? 0,7±0,04 - ?aaeoe?y aeoeaaoe??). Ia iiaeia ia aa/eoe oaeiae, ui o an?o a?oiao iioa?i?eeo eiio?ieueii? a?oie aoea a?aenooiy ?aaeoe?y aeoeaaoe??, ui na?ae/eei i?i iaaeinoaoith eiiiainaoe?th ii?ooaiue aiiainoaco ? ae?aaeaiiio i?eai?/aii? ianiaoeeo?/ii? ?acenoaioiino? ? i?icaiaeueii? ?aaeoe?? i?aai?cio iaia/aieo. I?aeoaa?aeaeaiiyi neacaiiai aeua ? ? oa?aeoa? ci?i ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio ii A.E. Iae?th, aea/aiee iaie o 25 oai?eo iniiaii? a?oie ? 15 iioa?i?eeo eiio?ieueii? a?oie. Anoaiiaeaii, ui o an?o iioa?i?eeo ia?aeiii a?aei?/a?oueny cieaeaiiy ?ioiieia?/ii? ?aaeoeaiino? ia 14-15%. I?iaaaeaiiy aioo??oiueiaaiii? AA i?eaiaeeoue aei iinooiiaiai i?aeaeuaiiy ?? ia 12 aeiao i?aeoe/ii aei ii?iaeueiiai ??aiy, a aei 21 aeiae aiia ia?aaeuo? ii?io ia 7-8%, aeinyaath/e 76,3±3,9% i?e ii?i? 69-72%. A oie aea /an o oai?eo eiio?ieueii? a?oie aiia caeeoa?oueny aanue ia??iae aeine?aeaeaiue i?aeoe/ii ia iaeiiio ??ai? (62,6±3,9% ia 3-th aeiao; 58,4±3,3% ia 12 aeiao ? 60,2±3,1% ia 21 aeiao). ?acoeueoaoe i?iaaaeaieo aeine?aeaeaiue na?ae/aoue, ui canoinoaaiiy AA a eiiieaeni?e oa?ai?? a niieo/aii? c aeoeaiei o??o?a?/iei e?eoaaiiyi ii?eiaeo ?ai ? i?iaaaeaiiyi aie?eaoe?eii? ni?aoe?? ni?ey? i?aeaeuaiith ianiaoeeo?/ii? i?ioe?ioaeoe?eii? ?acenoaioiino? iaia/aieo a aino?ee ia??iae ii?eiai? oai?iae ? ia??iae i?aeaioiaee aei iia?aoeaiiai a?aeiiaeaiiy ao?a/aiiai oe??iiai iie?eao. Anoaiiaeaii, ui a?aenioie oaaioeeooth/eo eaeeioeeo?a ia 3-th aeiao ye o oai?eo iniiaii?, oae ? eiio?ieueieo a?oi aoa aenieei (97±3,6% ? 98±1,4% i?e ii?i? 50-70%). Oaaioeeoa?ia /enei neeaaeaei a?aeiia?aeii 14,1±1,5 ? 16,4±1,9. A oie aea /an a?aei?/aeanue iecueea ia?ao?aaethth/a caeaoi?noue i?e?iaieo ee?oei, neeaaeath/a 64±1,2 o oai?eo iniiaii? a?oie ? 52±1,4 - eiio?ieueii? a?oie. Aei 21-? aeiae oaaioeeoa?ia aeoeai?noue eaeeioeeo?a o oai?eo iniiaii? a?oie aeinoia??ii cieceeanue aei 76,5±1,4%, oaaioeeoa?ia /enei aeinoia??ii ciaioeeinue aei 9,4±1,1, i?ioeaio ia?aaa?aieo i?e?iaieo ee?oie aeinoia??ii c?inoaa aei 88±1,0%. ?ioa ea?oeia niinoa??aaeanue o iaia/aieo eiio?ieueii? a?oie, o yeeo aei oeeo no?ie?a aeinoia??ii aeueie caeeoaeanue oaaioeeoa?ia aeoeai?noue eaeeioeeo?a (89±0,9%), aeinoia??ii caeeoaeinue aenieei oaaioeeoa?ia /enei (14,8±1,8), caaa?oaii?noue oaaioeeoico oi/a aeinoia??ii ? c?inoaea (aei 67±2,8%), aea aoea ia 21% ieae/ith, i?ae o oai?eo iniiaii? a?oie. Oea na?ae/eei i?i cia/iee “ooieoe?iiaeueiee ia?ae?/” eaeeioeeo?a o oai?eo aac i?iaaaeaiiy AA. Aiaeia?/i? aeai? iaie aoee io?eiai? ? i?e aea/aii? aaeoa?eoeeaeii? aeoeaiino? ne?iaaoee e?ia?. O oai?eo iniiaii? ? eiio?ieueii? a?oi ia 3-th aeiao i?ney o?aaie aiia aoea aeinoia??ii ieae/ith ia 47,5% ? 50,0% a?aeiia?aeii, neeaaeath/e 42,0±1,6% ? 40,0±1,9%). I?e i?iaaaeaii? AA aaeoa?eoeeaeia aeoeai?noue ne?iaaoee o iioa?i?eeo iniiaii? a?oie iinooiiai c?inoaea ? aei 21 aeiae aeinyaaea aa?oiuei? iaae? ii?ie (82,0±2,9%). O oai?eo eiio?ieueii? a?oie aiia oaeiae ca?eueooaaeanue, aea aei oeeo no?ie?a neeaaeaea eeoa 68,0±3,0% ? aoea aeinoia??ii ieae/ith ia 17,1% (?< 0,01). Aecia/aii, ui o iaia/aieo aaea ia 3-th aeiao i?ney o?aaie ?icaeaa?oueny aoi?eiiee ?ioiiaeao?oeeoiee noai ye ii oeio ee?oeiii?, oae ? aoii?aeueii? eaiee ?ioi?oaoo, ae?aaeaii?noue yeiai ciaoiaeeoueny a i?yi?e caeaaeiino? a?ae iaoiae?a e?eoaaiiy ii?eiai? oai?iae. Aeyaeaii cieaeaiiy a ia?eoa?e/i?e e?ia? a?aeiiniiai neeaaeo (ia 39%) A-?IEo (ia 28,1%), A-?IEa (ia 11,9%), noaiiioeyoe?e O-e?ioioeeo?a (OO? ia 29,7, OO* ia 25,4%) ? ?o ni?aa?aeiioaiiy, ?ioiiaeiaoe?i?a eeano I, ??ciiiai?aaeai? ci?ie ?ioiiaeiaoe?i?a iniiaieo eean?a. Iieacaii, ui canoinoaaiiy ia i?ioyc? 3-o oeaei?a AA i?eaiaeeoue aei iaeiiiai?aaeaiiai ca?eueoaiiy neeaaeo ?ioiiaeiaoe?i?a an?o eean?a, iniaeeai eeano Ig I i Ig G (ia 12,5% ? 24,3% a?aeiia?aeii), cieaeaiiy aeen?ioiiaeiaoe?iai??. I?e oeueiio, ??ai? ?ioiiaeiaoe?i?a an?o eean?a noaaaee a?eueo aenieeie, i?ae o caei?iaeo ethaeae. Ca?eueoaiiy e?eueeino? Ig G a ne?iaaooe? ia?eoa?e/ii? e?ia? a oeae ia??iae o oai?eo iniiaii? a?oie aei 12,8±0,67 a/e, i?e ciaioaii? aeen?ioiiaeiaoe?iai??, na?ae/eei i?i ia?aeeth/aiiy A-e?ioioeeo?a ia neioac Ig G - aioeo?e c a?eueo aenieei ao?i?oaoii aei ??cieo aioeo?e, ye? aeiaaathoue o/ano? O-e?ioioeeo?a (?.A. Oien, 1987). Ee?i?/ia aoaeoeai?noue AA. Iaie aia?oa anoaiiaeaii, ui iaea?eueo aoaeoeaiith ? iaoaia?ii-naaiaioa?ia AA, yeo ie canoinoaaee o 17,75% oai?eo. E?aoiee a?aenioie ?? aoaeoeaiino? neeaa 4,60. Aeinoaoiuei aeniea aoaeoeai?noue a?aei?/aeanue i?e ciiaeuei?e, eaiaeuei?e ? aioo??oiueiaaii?e AA, ye? i?iaiaeeeenue a?aeiia?aeii o 11,83%, 13,97% ? 12,36% oai?eo. E?aoiee a?aenioie ?o aoaeoeaiino? aoa a?ae 2,71 aei 2,30. Iaio aoaeoeaieie aoea ?aciiainia, i?io?eaeoe/ia AA ? a?iaia?aiianaae, e?aoiee a?aenioie aoaeoeaiino? yeeo neeaa a?ae 1,14 aei 0,88. I?e oeueiio, ine?eueee i?e i?iaaaeaii? AA aeaeo?iaeii-aeiii?ii aoea ni?aoe?eia iia’ycea AOAI ? aiia caieiaeoaaeanue aai ?ic/eiii oo?aoeee?io c aioea?ioeeaie, aai 3-5% ?ic/eiii ae?iaeneaeo, oi i?aeoe/ii o an?o iaoe??io?a iniiaii? a?oie ii?yae c AA, iaeii/anii i?iaiaeeany a?ioi?ac aioeaaeoa??aeueieo i?aia?ao?a a iaeano? an?o ii?eiaeo ?ai aai cia/i?e ?o /anoei?. Iaie iieacaii, ui i?iaaaeaiiy AA i?eaiaeeoue aei iie?auaiiy ?aia?aoeaieo i?ioean?a. Oea i?iyaey?oueny naiino?eiei a?aeoiaeaeaiiyi iae?ico ia 8-14 aeiao o oai?eo iniiaii? a?oie, i?ioe 11-16 ae?a o oai?eo eiio?ieueii? a?oie, ai?oae?caoe??th ia 4-5 aei?a ?ai?oa iiaa?oiaaeo ii?e?a IIIA noai?i? (19,5±0,19 aeiy i?ioe 24,2±1,2 aeiy a eiio?ieuei?e a?oi? - ?<0,05), a?eueo oaeaeeei ?icaeoeii a?aioeyoe?e ? i?iaaaeaiiyi ia 7-10 aei?a ?ai?oa ia?oeo aooiaea?iiieanoee (ia 14-17 aeaiue i?ioe 21-27 aei?a a eiio?ieuei?e a?oi? - ?<0,01) c i?eaeeaeaiiyi a?eueoa 95% ia?anaaeaeaieo oe??ieo eeaio?a, cieaeaiiyi e?eueeino? aooiaea?iiieanoee ia iaeiiai oai?iai ia 20% (2,4 a iniiai?e ? 3,0 a eiio?ieuei?e a?oiao). Nooo?ai nei?ioeeenue ? no?iee e?eoaaiiy oai?eo c ii?eaie IIIA-IV noai?i? (ia 12,1 ? 12,9 aei?a) 45,7±1,4 ? 63,4±2,4 i?ioe 57,8±3,9 ? 76,3±2,8 aei?a a eiio?ieuei?e a?oi? a?aeiia?aeii (?<0,05 ? ?<0,01). Ii?yae c iie?auaiiyi ia?aa?ao ii?eiaeo ?ai, canoinoaaiiy AA i?eaiaeeei aei aeinoia??iiai cieaeaiiy a 1,7 ?aca /anoioe ??cieo oneeaaeiaiue ii?eiai? oai?iae (40,9% a iniiai?e ? 72,4% a eiio?ieuei?e a?oiao), a oiio /ene? cieaeaiiy naineno a 1,7 ?ac (17,2% a iniiai?e ? 29,8% a eiio?ieuei?e a?oiao), cieaeaiiy /anoioe oneeaaeiaiue c aieo i?aai?a aeeoaiiy a 1,8 ?ac (11,3% a iniiai?e ? 20,7% a eiio?ieuei?e a?oiao), c aieo i?aai?a oeoieiai-eeoeiaiai o?aeoo a 1,9 ?ac (5,4 a iniiai?e ? 10,3 a eiio?ieuei?e a?oiao), c aieo ie?ie a 1,5 ?ac (4,3 a iniiai?e ? 6,8 a eiio?ieuei?e a?oiao), c aieo na?oeaai-noaeeiii? nenoaie a 1,7 (2,7 a iniiai?e ? 4,6 a eiio?ieuei?e a?oiao). Aia?oa iaie ?ic?iaeai? iaoiaee AA i?e aaaeeeo ia?acao eeoa/ieea (18 ae?oae) ? a?ioi?aco e?ea?nueeeo ?a/iaei i?e iiaaiii?yo (22 ae?oae) iieacaee ?o aenieo aoaeoeai?noue, ni?eyee oaeaeeiio a?aeiiaeaiith ia?enoaeueoeee eeoa/ieea, nei?i/aiith no?ie?a e?eoaaiiy iiaaiii?e (9,0±0,7 aei?a a iniiai?e ? 17,0±1,5 aei?a a eiio?ieuei?e a?oiao - ?<0,001). Iie?auaiiy ia?aa?ao ii?eiaeo ?ai, cieaeaiiy /anoioe oneeaaeiaiue ii?eiai? oai?iae i?e canoinoaaii? AA i?eaiaeeei aei cieaeaiiy eaoaeueiino? iaia/aieo. I?e oeueiio caaacia/o?oueny iaeoaeaiiy an?o iioa?i?eeo iniiaii? a?oie c o?aaeaiiyie eaaei? noai?i? (I-a a?oia) i?e eaoaeueiino? 3,6% a eiio?ieuei?e a?oi?, cieaeaiiy eaoaeueiino? o oai?eo c ii?eaie na?aaeiuei? noai?i? aaaeeino? (II-a a?oia) a 5,6 ?ac (2,5% a iniiai?e ? 13,9 a eiio?ieuei?e a?oiao), a 2,6 ?ace o iioa?i?eeo c aaaeeeie ii?eaie (10,6% a iniiai?e ? 27,5% a eiio?ieuei?e a?oiao) ? a 1,9 ?ace o oai?eo c ae?ae aaaeeeie ii?eaie (45,8% a iniiai?e ? 85,3% a eiio?ieuei?e a?oiao). I?eaaaeai? iaie ?acoeueoaoe e?eoaaiiy aino?iai ia??iaeo ii?eiai? oai?iae c canoinoaaiiyi a eiiieaeni?e oa?ai?? AA na?ae/aoue i?i nooo?aa i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy iioa?i?eeo c oe??th aaaeeith iaoieia??th. ?acoeueoaoe i?iaaaeaiiai aeine?aeaeaiiy iaa?oioiaothoue aeioe?euei?noue ? aeiaiaeyoue iaiao?aei?noue aeeth/aiiy AA a nenoaio e?eoaaiiy iaia/aieo, ui aeicaieeoue nei?ioeoe no?iee e?eoaaiiy, ciaioeoe eaoaeuei?noue iioa?i?eeo. Oei naiei aeeiiaia iinoaaeaia oe?eue aeine?aeaeaiiy, ui aeicaiey? iai c?iaeoe ianooii? aeniiaee. Aeniiaee 1. I?eeiyoa nenoaia e?eoaaiiy oai?eo c ii?eiaith oai?iaith, caniiaaia ia canoinoaaii? o?ainooc?eii? oa?ai??, ?ici?uaii? oai?iai a ea?iaaiiio aaaeoa??aeueiiio na?aaeiaeu?, ia aeei?enoiao? a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a ? noi?iaiaeaeo?oueny o?eaaeeie no?ieaie iaeoaeaiiy (57,8-76,3 e/aei?a), aenieith /anoioith ?icaeoeo ?ioaeoe?eieo oneeaaeiaiue (39,8-72,4%), ? eaoaeueiino? oai?eo (27,5-85,3%) c aaaeeeie ? e?eoe/ieie ii?eaie. 2. Aino?ee ia??iae ii?eiai? oai?iae, yeee oa?aeoa?eco?oueny ae?aaeaiei neiae?iiii aiaeiaaiii? ?ioieneeaoe??, cia/ieie ii?ooaiiyie eooaiii-a?noea?aeueieo aca?iica’yce?a, noi?iaiaeaeo?oueny ??ceeie ci?iaie ooieoe?iiaeueii-aia?aaoe/ii? ??aiiaaae i?aai?cio iaia/aieo, no?eeino? eiai aaaaoaoeaii? ia?aiai? nenoaie, ye? noi?iaiaeaeothoueny ii?ooaiiyie aiiainoaco, i?e?iaeiuei? ?acenoaioiino? ? ia? ae?aaeaiee aieea ia ia?aa?a ? iane?aeee ii?eiai? oai?iae. 3. Iaoeiai iaa?oioiaaia ? aia?oa ?ic?iaeaia i?ia?aia, yea iai?aaeaia ia ii?iae?caoe?th eooaiii-a?noea?aeueieo aca?iica’yce?a oeyoii canoinoaaiiy a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a a aino?iio ia??iae? ii?eiai? oai?iae caaacia/o? ei?aeoe?th aiiainoaco, i?aeaeuaiiy i?e?iaeiuei? ?acenoaioiino? ? ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio iaia/aieo, ui iiceoeaii aieeaa? ia ia?aa?a ? iane?aeee ii?eiai? oai?iae. 4. Iaoiae a?iaia?aiae?aaiinoeee, a ooiaeaiaio yei? iieeaaeaia a?iaaeueaai?caoe?y, aeicaiey? ioe?ieoe i?e ??ci?e eieae?caoe?? ? iioe?aiino? ii?e?a ooieoe?iiaeueii-aia?aaoe/io ??aiiaaao i?aai?cio iaia/aieo, no?ee?noue eiai aaaaoaoeaii? ia?aiai? nenoaie ? i?iaiaeeoe oe?eani?yiiaaio ?o ei?aeoe?th, ui i?aeoaa?aeaeo?oueny ii?iae?caoe??th aaeaioaoe?eieo ?aaeoe?e o aaaeeiiaia/aieo aei e?ioey o?aoueiai - ii/aoeo /aoaa?oiai oeaeiy. 5. Iiceoeaiee aoaeo canoinoaaiiy a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a a eiiieaeniiio e?eoaaii? oai?eo a aino?iio ia??iae? ii?eiai? oai?iae aenia?eiaioaeueii i?aeoaa?aeaeaiee aaeoa??inoaoe/iith ? aaeoa?eoeeaeiith ae??th, i?aeaeuaiiyi aeaeo?ie?iaoe/iiai iioaioe?aeo ? aeoeaiino? iao???aeo ianin?a a?eo?ioeeo?a e?ia?, a?aeiiaeaiiyi i?e?ioee?eoeyoe??, iane/aiiyi oeaiei eeniai, c?inoaiiyi iecueeinieiiaeo noai?a aaiiaeia?io, ii?iae?caoe??th ?I e?ia?, cieaeaiiyi oiene/ieo aeanoeainoae e?ia?, noeioeyoe??th ?ioiii? nenoaie c iine?aeoth/ith ii?iae?caoe??th ooieoe?iiaeueii-aia?aaoe/ii? ??aiiaaae i?aai?cio ? no?eeino? aaaaoaoeaii? ia?aiai? nenoaie. 6. I?aeaeuaiiy ?ioiieia?/ii? ?aaeoeaiino? i?aai?cio i?e canoinoaaii? a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a ?aae?co?oueny ca ?aooiie noeioeyoe?? aoii?aeueiiai ? ee?oeiiiai ?ioi?oaoo, ui i?aeoaa?aeaeo?oueny ca?eueoaiiyi e?eueeino? ?ioiiaeiaoe?i?a A ia 20%, I ia 40%, G ia 18,8%, e?ioioeeo?a ia 32,7%, A-e?ioioeeo?a ia 26,4%, O-e?ioioeeo?a ia 20,9%, Oo - ia 30,6% i?e cieaeaii? On ia 17%. 7. Canoinoaaiiy iaoiae?a a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a a eiiieaeni?e oa?ai?? aino?iai ia??iaeo ii?eiai? oai?iae caiia?aa? iiaeeaeaiith ii?eiaeo ?ai, ciaioo? ieiuo aeeaieeo ii?e?a, cieaeo? e?euee?noue ?ioaeoe?eieo oneeaaeiaiue ia 43,5%. I?e oeueiio caaacia/o?oueny iaeoaeaiiy an?o iioa?i?eeo c ?iaeaenii aaaeeino? o?aaeaiiy I no. (?AO) ? cieaeaiiy eaoaeueiino? oai?eo c ?AO II no. a 5,6 ?ac, III no. a 2,6 ?ac ? IV no. a 1,9 ?ac i?e nei?i/aii? no?ie?a e?eoaaiiy c ii?eaie na?aaeiuei? noai?i? ia 24,8%, aaaeei? noai?i? ia 20,9% ? ae?ae aaaeei? ia 16,9%. NIENIE IIOAE?EIAAIEO I?AOeUe CA OAIITH AeENA?OAOe?? 1. Aeiaaeueaaiecaoeey a eiiaonoeieiaee. Iiiia?aoey. - Aeiieoea: ?aeoeiia?ao?y, Canoaaia, 1993.- 330 n. /Ni?aaao. A.A. Iaeaoe, I.A. Iianoyiie/ 2. A?iaaeueaai?caoe?y ye i?io?eaeoe/iee ? e?eoaaeueiee iaoiae ia?ae?oe/ii? iai?io?aeiino? o ae?oae // A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1998.- 2.1.98.- 180-181. 3. A?iaaeueaai?caoe?y - iiaee o?c?ioa?aiaaoe/iee iaoiae e?eoaaiiy ii?e?a ? aeaeo?io?aaeaiue eeoeoe? oa i?iiaiaaicaiynoiiai noaeiao //A?niee A?iieoeueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.- 1998.-2.1.98. n.182-183. 4. Aieea a?iaaeueaai?caoe?? ia e?euee?noue e?ioioeeo?a a aino?iio ia??iae? ii?eiai? oai?iae a caeaaeiino? a?ae ?iaeaeno aaaeeino? o?aaeaiiy. I?ioa?ai?y. //Aeaaeai?y i?iaeai a?iien??, iaoe?iiaeueia aeaaeai?y iaoe Oe?a?ie, ?inoeooo o?c?ieia?? ?i. I.I. Aiaiiieueoea.- Ee?a.- 1998.- N. 115-116. 5. Oecei- oa ?aoeaenioa?aiaaoe/aneia i?eiaiaiea iai?aaeaiiiai ia?aiina naiaiaeiuo ca?yaeiiineoaeae a aeoioieoo?iuo ooieoeeiiaeueiuo eaiaeao e ?acee/iuo no?oeoo?ao aeieiae/aneeo nenoai (Ni?aao. A.A. Iaeaoe, I.A. Iianoyiie, ?.A. Iaeaoe, A.I. Eieyaeaiei, I.I. Aoiueei, TH.I. Eaaeoaa). Aao. na. i?i iaoeiao ?ic?iaeo ?3 a?ae 19.03.1988 ?. Aiioaoe?y Iaaae/oe A.?. A?iaaeueaai?caoe?y a aino?iio ia??iae? ii?eiai? oai?iae. - ?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy, eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?aeuei?noth 14.01.03. - o??o?a?y. - A?iieoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao ?i. I.?. Ie?iaiaa, A?iieoey, 1998. Aeena?oaoe?y i?enay/aia ieoaiiyi oa?ai?? ii?e?a, i?e aeei?enoaii? a eiiieaeniiio e?eoaaii? iaoiae?a a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo i?aia?ao?a. Iaaaaeai? ?acoeueoaoe e?eoaaiiy 360 oai?eo ??cii? noai?i? aaaeeino?. Iaa?oioiaaii aeioe?euei?noue canoinoaaiiy a?iaaeueaai?caoe?? ? a?ioi?aco e?ea?nueeeo ?a/iaei oa ?ic?iaeai? iaoiaee ? noaie ?o aeei?enoaiiy a eiiieaeniiio e?eoaaii? ii?e?a ??cii? noai?i? aaaeeino?. Ciaioaia e?euee?noue ?ioaeoe?eieo oneeaaeiaiue ia 43,5%. Ciaioaia eaoaeuei?noue oai?eo c ?iaeaenii aaaeeino? o?aaeaiiy II no. a 5,6 ?ac, III no. a 2,6 ?ac i IV no. a 1,9 ?ac. Nei?i/ai? no?iee e?eoaaiiy iioa?i?eeo c ii?eaie na?aaeiuei? noai?i? aaaeeino? ia 24,8%, aaaeei? noai?i? ia 20,9% ? ae?ae aaaeei? ia 16,9%. Eeth/ia? neiaa: ii?ee, ii?eiaa oai?iaa, aino?ee ia??iae ii?eiai? oai?iae, a?iaaeueaai?caoe?y, a?ioi?ac, a?iaia?aiae?aaiinoeea, a?iaia?aiei?aeoe?y, aiiainoac. AiIioaoeey Iaaae/oe A.E. Aeiaaeueaaiecaoeey a ino?ii ia?eiaea iaeiaiaie aieacie. - ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.01.03 - oe?o?aey. - Aeiieoeeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao ei. I.E. Ie?iaiaa, 1998. Aeenna?oaoeey iinayuaia aii?inai oa?aiee iaeiaia i?e eniieueciaaiee a eiiieaeniii ea/aiee iaoiaeia aeiaaeueaaiecaoeee e aeioi?aca eaea?noaaiiuo i?aia?aoia. Inaauathony ?acoeueoaou ea/aiey 360 aieueiuo ?acee/iie noaiaie oyaeanoe. Iainiiaaii oeaeaniia?aciinoue e iaoiaaiaoe/iinoue eniieueciaaiey aeiaaeueaaiecaoeee e aeioi?aca eaea?noaaiiuo aauanoa, ?ac?aaioaiu iaoiaeu e noaiu eo eniieueciaaiey a eiiieaeniii ea/aiee iaeiaia ?acee/iie noaiaie oyaeanoe. Oiaiueoaii eiee/anoai eioaeoeeiiiuo ineiaeiaiee ia 43,5%. Nieaeaia eaoaeueiinoue aieueiuo n eiaeaenii oyaeanoe ii?aaeaiey II no. a 5,6 ?ac, III no. a 2,6 ?ac e IV no. a 1,9 ?ac. Nie?auaiu n?iee ea/aiey iino?aaeaaoeo n iaeiaaie n?aaeiae noaiaie ia 24,8%, oyaeaeie noaiaie ia 20,9% e e?aeia oyaeaeie ia 16,9%. Eeth/aaua neiaa: iaeiae, iaeiaiaay aieaciue, ino?ue ia?eiae iaeiaiaie aieacie, aeiaaeueaaiecaoeey, aeioi?ac, aeiyia?aiaeeaaiinoeea, aeiyia?aiei??aeoeey, aiiainoac. Annotation Nagauchuk V.I. Biogalvanization in acute phase of the disease due to burns - Manuscript. Thesis for a degree of medical science candidate, speciality 14.01.03. - surgery. The Pirogov Vinnitsa State Medical University. Vinnitsa, 1998. The thesis touches burn therapy problem by using biogalvanization methods and biophoresis of medicinal preparations. The results of 360 patients treated for different burn severity degree are given. Expedience of using biogalvanization and biophoresis of medicinal preparations has been proved, methods and schemes of employement have been claborated in complete treatment different severity burns. The incidence of infections complications decreased by 43,5%. Death rate due to II degree burns reduced 5,6 times, III degree burns 2,6 times and IV degree burns 1,9 times. The term of treatment moderate degree burns is shortened by 24,8%, severe burns by 16,9%. Key words: burns, acute phase of disease due to burns, biogalvanization, biophoresis, bioenergethic diagnosis, bioenergetic correction, homeostasis. I?aeienaii aei ae?oeo 5.10.98 ?. Caiiae. ? 135. Oi?iao 60o90 1/16 Oi. ae?oe. a?e. 1,0 Ae?oe ionaoiee. Oe?aae 100 i?ei??iee?a. A?iieoey. Ae?oea?iy AAeIO ?i. I.?.Ie?iaiaa, Ie?iaiaa, 56.

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