.

Біоенергетичні зміни при хронічних порушеннях мозкового кровообігу: Автореф. дис… д-ра мед. наук / О.Г. Морозова, Харк. ін-т удоскон. лікарів. — Х.,

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OA?E?ANUeEEE ?INOEOOO OAeINEIIAEAIIss E?EA??A

II?ICIAA Ieueaa A?eai??aia

OAeE: 616.831-005-036.12-008.9

A?IAIA?AAOE*I? CI?IEI?E O?II?*IEO II?OOAIIssOIICEIAIAI E?IAIIA?AO

14.01.15 – Ia?aia? oai?iae

Aaoi?aoa?aoaeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiyaeieoi?a iaaee/ieo
iaoe

Oa?e?a – 1998

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia a Oa?e?anueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao?

Iaoeiaee eiinoeueoaio – Caneoaeaiee ae?y/ iaoee Oe?a?ie,Eao?aao
Aea?aeaaii? i?ai?? Oe?a?ie,aeieoi? iaaee/ieo iaoe, i?ioani?Aeoaaiei
?aaai A?eai?iae/,Oa?e?anueeee aea?aeaiee iaaee/iee oi?aa?neoao,caa.
eaoaae?ith ia?aiaeo oai?ia

Io?oe?ei? iiiiaioe: – Caneoaeaiee ae?y/ iaoee ? oaoi?ee
Oe?a?ie,aeieoi? iaaee/ieo iaoe, i?ioani?Aecye Ethaeieea
Aioii?aia,Aei?i?iiao?ianueea iaaee/ia aeaaeai?y,caa. eaoaae?ith
iaa?ieia?? oa iae?io??o?a??

– aeieoi? iaae/ieo iaoe, i?ioani??uaiei Ieoaeei
Ieoaeeiae/,Oa?iii?euenueea iaaee/ia aeaaeai?y,i?ioani? eaoaae?e
iaa?ieia??

– aeieoi? iaae/ieo iaoe, i?ioani?Iaca?aiei Aaaeei
A?eai?iae/,Aeiiaoeueeee iaaee/iee oi?aa?neoao,caa. eaoaae?ith iaa?ieia??

I?ia?aeia onoaiiaa – IAe? aa?iioieia?? AII Oe?a?ie,
a?aeae?eaeno?ai??ai?aeii? iaoieia??, i.Ee?a

Caoeno aeena?oaoe?? a?aeaoaeaoueny “ 9 ” a?oaeiy 1998 ?. i 10 aiaeei? ia
can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 64.609.01 i?e Oa?e?anueeiio
?inoeooo? oaeineiiaeaiiy e?ea??a I?i?noa?noaa ioi?iie caei?ia’y Oe?a?ie
ca aae?anith: 310176, i.Oa?e?a, aoe Ei?/aa?ioe?a, 58.

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Oa?e?anueeiai
?inoeoooo oaeineiiaeaiiy e?ea??a (i.Oa?e?a, aoe. Ei?/aa?ioe?a, 58).

Aaoi?aoa?ao ?ic?neaiee 9 eenoiiaaea 1998 ?.

A/aiee nae?aoa? niaoe?ae?ciaaii? a/aii? ?aaee,

aeieoi? iaaee/ieo iaoe
?.A.A?eai?iaa33

CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE

Aeooaeueiinoue i?iaeaie. Noaeeiii caoai?thaaiiy aieiaiiai iiceo
caaaeyee cia/iiio ?iciianthaeaeaiith oa oyaeeei ianeiaeeai noaee
iaeaaaeeeaioith iaaee/iith oa nioeiaeueiith i?iaeaiith ye a iaoie
aea?aeaai, oae i a aieueoinoi aeiiiii/ii ?icaeiooeo e?a?i naioo.

O?iii/ii oi?ie noaeeiii? iaoieiai? aieiaiiai iiceo, yei o aio/eciyiie
eioa?aoo?i aeinoaee iacao aeenoee?eoeyoi?ieo aioeaoaeiiaoie (AeA),
cono?i/athoueny o 20 – 30% ethaeae i?aoeacaeaoiiai aieo (I.A.Aieioei,
1991-1997; E.A.Aecye ci niiaaao., 1996, 1997; A.TH.?oaeaiei, 1997;
I.A.Aa?auaaii, 1997; I.A.Iaiueeianueeee ci niiaao., 1996; I.I.Ea?aaaiue,
1997; ?.A.Oiiaeo, 1985).

I?ia?anoaaiiy o?iii/ii? iiceiai? aeenoee?eoeyoei? i?eaiaeeoue aei
iiaeeaeaiiy iaa?ieiai/iiai aeaoioeeoo, ?icaeoeo noaeeiieo aeaiaioeie,
iiai?oaiiy yeinoi aeeooy oa iiaaeiaeecaoei? oai?eo.

Ca inoaiii aeanyoe?i//y iaeiie/aii /eneaiii aeaii i?i iaoaiicie
oi?ioaaiiy o?iii/ieo ii?ooaiue iiceiaiai e?iaiiaiao (OIIE), ?o eeiii/ii
i?iyae, iniaeeainoi ia?aaiao i?e ?iciie aoeieiai?, oaeoi?e ?eceeo, oeyoe
i?ioieaeoeee i oa?aii? (I.A.Aieioei, A.E.Oaeoee?i, 1991; I.I.Iuaiei ci
niiaaao., 1985-1997; N.I.Aiie/oe, 1996-1997; ?.A.Aeoaaiei, 1989-1997;
A.A.Iaca?aiei, 1995-1997; A.I.Ie?oianueea, 1994-1996; I.A.Aeoaianueea,
1990-1992; I.A.Nei/ie, 1995-1997; I.I.A?eoeae, 1995-1997; I.A.Aeao?ia,
1990-1997; A.Ae.Aeaiaiei, 1996-1997; A.I.Oeieueiee, 1994-1997).

Iacaaaeath/e ia aaeeeo e?euee?noue ?ia?o a?aeiinii OIIE, aeaye? aniaeoe
iaoiaaiaco, ae?aaiinoeee, ia?aa?ao oa e?eoaaiiy o?ii?/ii? iiceiai?
aeenoee?eoeyoe?? iio?aaothoue iiaeaeueoiai aeine?aeaeaiiy. Ianaiia?aae
oea noino?oueny a?iaia?aaoeee, aea/aiiy yei? noaei iaeiith c
iaeaeooaeuei?oeo i?iaeai no/anii? aia?iiaa?ieia??.

Oae, inoaii?i /anii oaaaa ee?i?oeeno?a oa aenia?eiaioaoi??a i?eaa?iooa
aei aeine?aeaeaiiy i?ioean?a iaoaaie?cio a ?oai?ciaai?e ia?aia?e oeaiei?
i?e aino?iio iiceiaiio ?inoeueo? (N.I.A?ie/oe, 1996; I.N.Cicoey ci
niiaaao., 1992; A.I.Canooa, 1996; ?.?.Aon?a c? ni?aaao., 1997;
H.Mochizuki et al., 1990; T.P.Obrenovitch, 1995). Iiyaa no/anieo
iaoiae?a aea/aiiy ii?oiooieoe?iiaeueieo iniaeeainoae aieiaiiai iiceo
c?iaeea iiaeeeaei i?eaeeoo?aa aeine?aeaeaiiy eiai iaoaaie?cio. Ca
aeiiiiiaith iiceo?iiii-ai?n?eii? oiiia?ao?? (I.Garcia et al., 1996) oa
iaai?oii-?aciiainii? niaeo?ineii?? c ?aae?iioee?aeii oinoi?a ?31
(M.Brant-Zawadzki et al., 1997) o oai?eo ia aino?o ?oai?th iiceo a cii?
“iaioia?e” ca?a?no?iaaii cieaeaiiy e?iaiia?ao aiane?aeie ciaioaiiy a i?e
iaoaaie?cio, a ia ?icaeoeo aeaeoeaiiai iae?ico.

Ooiaeaiaioaeueii aiioiii/ii oa iaoioiciieiai/ii aeineiaeaeaiiy
i?aeoaa?aeeee, ui aeeoo?caeaoiinoue aieiaiiai iiceo a ciii ioaii?
caeaaeeoue ia noieueee aiae ii?ooaiue aaiiaeeiaiiee, neieueee aiae
?iceaaeo iaoaaieicio a ioaiiciaaiie oeaieii iiceo (A.I.E?eaeaiianueeee,
1997; C.W.Olanow, 1993; T.Pozzan et al., 1994;). A aenia?eiaioi
anoaiiaeaii, ui aia?aaoe/iee aeaoioeeo, ii?ooaiiy
ieenethaaeueii-aiaeiiaethaaeueieo i?ioeania aiaeia?athoue i?iaiaeio
?ieue o aeaaaia?aoei? oa caaeaaei iae?iiia, a aieiaieie oiiaaie ?icaeoeo
aia?aaoe/iiai aeaoioeeoo ? ianoa/a eenith, ooeiaeaeaiiy iioioiiae?ie, a
yeeo neioacothoueny iae?ia?ai/ii niieoee, oa a?ae noano?aoo ieeneaiiy
aeey iiceo – aetheice (H.Monyer et al., 1992; M.F.Beal et al., 1993;
B.G.Ames et all, 1993).

Aea/aiiy iaoai?ci?a caaeaae? iae?ii?a i?e aino??e ?oai?? oa a?iien??
aeyaeei iaoieia?/io ?ieue iae?io?ainiiooa??a, ianaiia?aae – aethoaiaoo
(I.H.Laake, T.A.Slyngstad, 1995; I.J.Mitchell et all, 1994),
ia?aaaioaaeaiiy iae?iiia Na2+ (I.A.Aaaeiiii, A.A.Oea/oe, 1994;
M.I.Berridge, 1993; M.L.Mayer, R.I.Miller, 1991, R.J.White,
I.J.Reynolds, 1995) oa iineeaiiy i?ioeano ia?aeeniiai ieeneaiiy eiiiaeia
(I.I.Aanaeueneee, 1988-1997; O.C.Ia??nii, 1981; I.A.A?eai?iaa, 1997; T.
Funahashi et all, 1994).

I?e/iio iacaai? iaoiaaiaoe/i? eaioethae o?nii iia’ycai? c aia?aaoe/iei
iaoaaie?ciii, ui aeaco? ia i?ia?aeio ?ieue aia?aaoe/iiai caaacia/aiiy a
ooieoe?iioaaii? ia?aiaeo ee?oei (T.M.Dawson et al., 1992; F.Zhang et
al., 1993; P.Ienner. 1994; D.I.Hoffman et al., 1994; R.I.Whit et al.,
1995). Oiaoi aeine?aeaeaiiy a?iaia?aaoeee iathoue aaaeeeaa cia/aiiy ia
o?eueee aeey ooi/iaiiy iaoai?ci?a caaeaae? iae?ii?a i?e
oea?aa?iaaneoey?i?e iaoieia??, aea e aeey iiaeaeueoiai ?icaeoeo
eiioeaioe?? iae?ii?ioaeoe??.

Iaeiae aieueoinoue ?iaio uiaei aiiaia?aaoeee i?e oea?aa?aeueiie
iaoieiai? iineoue aenia?eiaioaeueiee oa?aeoa? aai noino?oueny aino?eo
ii?ooaiue iiceiaiai e?iaiiaiao. Aeineiaeaeaiiy aiiaia?aaoe/iiai
aiiainoaco i?e o?iii/iie iiceiaie aeenoee?eoeyoei? iaei/eneaiii,
oi?eathoueny eiai ie?aieo noi?ii i ia ae?ioothoue i?iaeaio a oeieiio.
Aeinueiaiaeii ia aeinoaee oaeiae iaeaaeiiai aenaioeaiiy
aiiaia?aaoe/ii-aaaaoaoeaii niiaaiaeiioaiiy, ui aaaeooue aei ?icaeoeo
iiceiai? aeenoee?eoeyoei?. Aaaeeeaei ? ? aea/aiiy iniaeeainoae
ooieoeiiioaaiiy aaaaoaoeaii? ia?aiai? nenoaie i?e OIIE, aa?o/e aei oaaae
?? oiiaa?naeueio o/anoue o ?aaoeyoei? aiiainoaco (I.I.Aaei ci niiaaao.,
1981-1997), a oiio /enei aia?aaoe/iiai iaoaaieicio.

Oaeei /eiii, i?iaeaia oi?ioaaiiy aioeaoaeiiaoie oianeiaeie o?iii/ii?
iiceiai? aeenoee?eoeyoei? c iiceoeie ii?ooaiue aiiaia?aaoeee, ca’yceo
oeeo ii?ooaiue ?c ?iceaaeii a ieneaeaioii-aioeieneaeaioiie,
iae?iaoii?aeueiie nenoaiao oa aaaaoaoeaiith aeec?aaoeyoei?th ia
?icaeyaeaeany. A aiia ? aaaeeeaith e ia?niaeoeaiith aianeiaeie iiaeo
iiaeeeainoae oa?aiaaoe/ii? ei?aeoei? aaea aeieeeeo eeiii/ieo i?iyaia, a
aieiaia – i?ioieaeoeee ?icaeoeo iaa?ieiai/iiai aeaoioeeoo.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoeiy
aeeiiaia aiaeiiaiaeii aei aea?aeaaieo eiiieaenieo iiaeaiaeii/eo i?ia?ai
“I?ioieaeoeea caoai?thaaiue i oi?ioaaiiy caei?iaiai niiniao aeeooy
ianaeaiiy Oe?a?ie ia ia?iiae aei 2000 ?ieo” i aiaeii/i? i?ia?aie
“Noaeeiii caoai?thaaiiy aieiaiiai iiceo”, ieaio iaoeiaeo aeineiaeaeaiue
Oa?eianueeiai aea?aeaaiiai iaaee/iiai oiiaa?neoaoo “Aea/aiiy caaaeueieo
caeiiiii?iinoae iaoiaaiaoe/ieo i?ioeania oa ?ic?iaea niiniaia ?o
ei?aeoei?” oa a ?onei iaoeiai-aeineiaeii? ?iaioe eaoaae?e ia?aiaeo
oai?ia OAeIO “Iaoaiicie oi?ioaaiiy o?iii/ieo ii?ooaiue iiceiaiai
e?iaiiaiao” (N aea?ae?a?no?aoei? 01950023465).

Iaoa aeineiaeaeaiiy. Anoaiiaeaiiy ?iei ii?ooaiue aiiaia?aaoe/iiai oa
iae?iaoii?aeueii-aaaaoaoeaiiai aiiainoaco a oi?ioaaiii o?iii/ii?
iiceiai? aeenoee?eoeyoei? oa iniaeeainoae ?? ia?aaiao i?e a?oa?iaeueiie
aiia?oaici?, aoa?ineea?ici i ?o ii?aeiaii?, a oaeiae ?ic?iaea iaoiaeia
ia?aeiii? i aoi?eiii? i?ioieaeoeee oa eieoaaiiy a caeaaeiinoi aiae noaio
aia?aaoe/iiai iaoaaieicio.

Iniiaii caaaeaiiy ?iaioe:

1. Aea/eoe iniaeeainoi aiiaia?aaoeee o oai?eo ia o?iii/io iiceiao
aeenoee?eoeyoeith (ieenethaaeueiiai oinoi?eethaaiiy, iaioiciiai oeeeeo
oa aiaa?iaiiai aeieieico) oa ioeiieoe ?o o caeaaeiinoi aiae eeiii/ii?
noaaei? aeenoee?eoeyoi?ii? aioeaoaeiiaoi?, aoeieiai? aeenoee?eoeyoei?,
noaio oeaio?aeueii? oa oea?aa?aeueii? aaiiaeeiaiiee, no?oeoo?ieo oa
ooieoeiiiaeueieo noaiia aieiaiiai iiceo.

2. I?iaanoe aenia?eiaioaeueia aeineiaeaeaiiy aia?aaoe/iiai iaoaaieicio
i?e iiaeaeueiiio aoa?ineea?ici c aecia/aiiyi aeoeaiinoi
iioioiiae?iaeueieo, aeieieioe/ieo oa?iaioia, Na-AOOace, ??aiy
aioo?ioiueieeioeiiiai eaeueoe?th oa i?ioeania IIE.

3. Ioeiieoe aiiaia?aaoe/ii iieacieee a caeaaeiinoi aiae noaio
ieneaeaioii-aioeieneaeaioieo nenoai, eiiiaeiiai iaiiio, ?iaiy aiiaaiieo
iiiiaiiiia, iae?iiaaeiaoi?ieo aiiiieeneio, i?inoaoeeeeii-o?iiaienaiiaiai
niiaaiaeiioaiiy oa nooiaiy aaaaoaoeaii? aeenooieoei?.

4. Aeyaeoe ?ieue aiiaia?aaoe/ii-iae?iaoii?aeueieo niiaaiaeiioaiue oa
iniaeeainoae aaaaoaoeaii? ?aaoeyoei? a oi?ioaaiii eeiii/ieo neiae?iiia.

5. Ia iiaenoaai aecia/aiiy iniaeeainoae aiiaia?aaoe/iiai oa
aaaaoaoeaiiai aiiainoaco o ethaeae c iniiaieie oaeoi?aie ?eceeo
oea?aa?i-aaneoey?ii? iaoieiai? oa aeaieo i?iniaeoeaiiai niinoa?aaeaiiy
ca oai?eie c ?icieie aa?iaioaie aiiaia?aaoe/ii-aaaaoaoeaieo
niiaaiaeiioaiue aeiaanoe iiaeeea?noue i?iaiicoaaiiy ia?aaiao o?iii/ieo
ii?ooaiue iiceiaiai e?iaiiaiao.

6. Aea/eoe iiaeeeainoi ia?aeiii? i aoi?eiii? i?ioieaeoeee o?iii/ii?
iiceiai? aeenoee?eoeyoei? oa ?ic?iaeoe noaie iaoiaaiaoe/iiai eieoaaiiy
AeA c a?aooaaiiyi iieacieeia aiiaia?aaoe/iiai, aaaaoaoeaiiai i
iae?iaoii?aeueiiai aiiainoaco.

Iaoeiaa iiaecia io?eiaieo ?acoeueoaoia. O ?iaioi aia?oa eiiieaenii a
eeiiioei oa aenia?eiaioi aeineiaeaeaia ?ieue aiiaia?aaoe/ieo ciii o
oi?ioaaiii oa ia?aaiaiai o?iii/ieo ii?ooaiue iiceiaiai e?iaiiaiao.
Anoaiiaeaii, ui iaoiaaiaoe/iei iaoaiiciii ?icaeoeo aioeaoaeiiaoi? i?e
o?iii/iie iiceiaie aeenoee?eoeyoei? ? aia?aaoe/iee aeaoioeeo, yeee
iia’ycaiee ic cieaeaiiyi aeoeaiinoi iioioiiae?iaeueieo oa?iaioia i
i?eaii/aiiyi i?ioeania ieenethaaeueiiai oinoi?eethaaiiy a iioioiiae?iyo
aianeiaeie aiiieni? a oiiaao ii?ooaiiy aaiiaeeiaiiee, iniaeeai a
iie?ioee?eoeyoi?iiio ?onei. Aeyaeaii niieo/aiiy cieaeaii?
aia?aicaaacia/aiiinoi c iaia?aiiith iaoieiai?th o aeaeyaei ciii
no?oeoo?iiai ?iciiaeieo o?aeoeie oinoieiiiaeia, i?aeaeuaiiyi aeoeaiino?
ia?ea?ieo iaia?aiica’ycaieo oa?iaio?a, a oaeiae iaeiie/aiiyi
aioo?ioiueieeioeiiiai eaeueoeith i iineeaiiyi i?ioeania IIE.
Anoaiiaeaiee ca’ycie aiiaia?aaoe/ieo ciii c iaoieiai/ieie c?ooaiiyie a
nenoaiao iae?iiaaeiaoi?ieo aiiiieeneio, i?inoaii?aeia oa aiiaaiieo
iiiiaiiiia. I?iaiaeiciaaii iniaeeainoi aiiaia?aaoeee a caeaaeiinoi aiae
ae?aaeaiinoi no?oeoo?ieo ciii aieiaiiai iiceo. Anoaiiaeaii, ui
iaecia/iioee aia?aaoe/iee aeaoioeeo ?icaeaa?oueny i?e aeeoociie
iaoieiai? aieiaiiai iiceo o aeaeyae? /eneaiieo ae??aiiina?aaeeiaeo
?ioa?eo?a oa eaeeia?aico.

Iieacaii, ui ia ii/aoeiaie noaaei? OIIE ?icaeaathoueny aaeaioeaii
c?ooaiiy, yei iieyaathoue o iineeaiii aiaa?iaiiai aeieieico, c?inoaiii
aioeieneaeaioii? aeoeaiinoi, iiaeaeuaiii ?iaiy iae?iiaaeiaoi?ieo
aiiiieeneio, a oaeiae aaaaoaoeaiie a?aio?iiiie aeoeaaoei?. Iiaeaeueoa
i?ia?anoaaiiy OIIE iia’ycaia c aeacaaeaioeaieie c?ooaiiyie, ?acoeueoaoii
yeeo ? cieaeaiiy aaaaoaoeaiiai caaacia/aiiy aiiaieiiaoe/ieo i?ioeania,
iineeaiiy IIE, iiaeeaeaiiy iaia?aiii? iaoieiai?, i?eaii/aiiy anio
oeeeeia aia?aaoe/iiai iaoaaieicio, ui iineeth? aia?aaoe/iee aeaoioeeo.

Oia?oa ia iiaenoaai i’yoe-ainueie?i/iiai i?iniaeoeaiiai aeineiaeaeaiiy
oai?eo ia o?iii/io iiceiao aeenoee?eoeyoeith iiaeoaa?aeaeaia ?ieue
ii?ooaiue aiiaia?aaoeee oa ?? ?aaoeyoei? c aieo aaaaoaoeaii? ia?aiai?
nenoaie a ?icaeoeo oa i?ia?anoaaiii OIIE. Aeyaeaii iaeni?eyoeeaioi oa
iaeiani?eyoeeaioi uiaei ?icaeoeo aeenoee?eoeyoi?ii? aioeaoaeiiaoi? oeie
aaaaoaoeaii? ?aaoeyoei? i aiiaia?aaoe/ii-iae?iaoii?aeueii-aaaaoaoeaieo
niiaaiaeiioaiue.

Aeyaeaia iiaeeeainoue aaeueioaaiiy i?ioeania o?iii/ii? iiceiai?
aeenoee?eoeyoei? oeyoii aieeao ia aiiaia?aaoe/ii oa aaaaoaoeaii
iieacieee. Aeiaaaeaii iiina?aaeeiaaio aeith oa?aii?, ui ?aaoeth?
aiiaia?aaoe/ii i?ioeane, ia noai oea?aa?aeueii? aaiiaeeiaiiee.

Oia?oa aea/aii eeiiiei-aiiaia?aaoe/ii niiaaiaeiioaiiy, ui aeicaieeei
aecia/eoe ?ieue a?iaia?aaoe/ieo ci?i o oi?ioaaii? ee?i?/ii?
iaa?ieia?/ii? nai?ieia??. Iieacaii, ui iniae c iniiaieie oaeoi?aie
?eceeo oea?aa?iaaneoey?ii? iaoieiai? aac eeiii/ieo i?iyaia caoai?thaaiiy
iathoue aiaeiiiiee aiae caei?iaeo oei aaaaoaoeaii? ?aaoeyoei? oa
aiiaia?aaoe/iiai aiiainoaco.

I?aeoe/ia cia/aiiy ?iaioe. Ia iniiai io?eiaieo ?acoeueoaoia
aeineiaeaeaiiy aeiaaaeaia iiaeeea?noue i?iaiicoaaiiy ?icaeoeo OIIE a
caeaaeiinoi aiae oeio aaaaoaoeaii-aiiaia?aaoe/ieo niiaaiaeiioaiue, ui
aeicaieeoue iaoiaaiaoe/ii iaa?oioiaaii i?iaiaeeoe i?ioieaeoeeo o?iii/ii?
iiceiai? aeenoee?eoeyoei?. Aeyaeaii ca’ycee iiae niaeo?aie iiooaeiinoae
iniiaieo aiiaeaeo?e/ieo ?eoiia ii aeaieo AAA oa nooiaiai aia?aaoe/iiai
aeaoioeeoo, ui aeicaieeoue oaeineiiaeeoe ?aiith aeiaaiinoeeo ii?ooaiue
aia?aaoe/iiai iaoaaieicio i?e OIIE oa eiio?iethaaoe aoaeoeaiinoue
oa?aiaaoe/ieo caoiaeia.

Iieacaia aeioeieueiinoue oa aei?ainoue ia?aeiii? oa aoi?eiii?
i?ioieaeoeee OIIE ia iniiai ei?aeoei? aiiaia?aaoe/ieo ciii.

?acoeueoaoe aeineiaeaeaiue aeiaaee, ui aeey i?ioieaeoeee aia?aaoe/iiai
aeenaaeaino i caioneo aiiaia?aaoe/ieo iaoaiiciia ?icaeoeo oea?aa?aeueii?
aeenoee?eoeyoei? o inia c oaeoi?aie ?eceeo oea?aa?i-aaneoey?ii?
iaoieiai? iio?iaai eiiieaen caoiaeia, yeee aeeth/a? aaeaeaaoiee ?ooiaee
?aaeei, ieneaaiioa?aiith, ineoioa?aiaaoe/ii, ?aoeaeoi?ii aei?,
naaeaoeaii, aaaaoio?iiii, AAIE-a?ai/ii i?aia?aoe, aaeaioiaaie oa
aeoeaaoi?e aiiaia?aaoe/ieo i?ioeania.

A caeaaeiinoi aiae iniaeeainoae ii?ooaiue aiiaia?aaoeee ?ic?iaeaii
noaie iaoiaaiaoe/iiai eieoaaiiy ia eiaeiie noaaei? aeenoee?eoeyoi?ii?
aioeaoaeiiaoi?. Aeiaaaeaia iae?ii?ioaeoi?ia oa aaciaeoeaia aeiy
i?aia?aoia-aeoeaaoi?ia iaoaaiei/ieo i?ioeania. ?acii c oei, aeyaeaiee
aeoeaoth/ee aieea iiiioa?aii? aeacaieie i?aia?aoaie ia i?ioeane
aieueii-?aaeeeaeueiiai ieeneaiiy, iniaeeai o oai?eo c ae?aaeaiith
iiceiaith aeenoee?eoeyoei?th. Oea naiae/eoue i?i iaiaoiaeiinoue
canoinoaaiiy aeoeaaoi?ia iaoaaiei/ieo i?ioeania oieueee a niieo/aiii c
iaia?aiii?ioaeoi?aie o aeaeyaei i?aia?ao?a aioeieneaeaioii? ae??.

?ic?iaeaia iaoiaeeea ei?aeoei? aiiaia?aaoe/ieo ciii o oai?eo ia OIIE c
aeei?enoaiiyi iecueeiiioaineaiiai eaca?iiai ii?iiiithaaiiy oa
anoaiiaeaia ?? iae?ii?ioaeoi?ia aeiy.

Aeiaaaeaii, ui eiiieaen i?ioieaeoe/ieo oa eieoaaeueieo caoiaeia iiaeiai
oaeiae a?aoiaoaaoe oei aaaaoaoeaii? aeec?aaoeyoei?, iia’ycaiee c
iniaeeainoyie ?icaeoeo ?icieo aa?iaioia aeenoee?eoeyoei?. I?e
ia?iaiaioiiio oeiiai ia?aaiao neiae?iio aaaaoaoeaii? aeenoiii? iniaeeaa
oaaaa iiaeiia aooe caa?iaia ia eiiiaeiee niaeo? e?iai, aiiieiiiaeaii/ii
i?aia?aoe oa aioeieneaeaioe. I?e ia?ieneciaeueiiio c /anoeie
aaaaoaoeaiei e?ecaie – ia AAIE-a?ai/ii i?aia?aoe, ae?oeei,
o?aieaieicaoi?e, aeieaoi?e aaoa-aae?aia?ai/ieo ?aoeaioi?ia oa iiaiaioi?e
IAI.

?acoeueoaoe aeineiaeaeaiue ai?iaaaeaeaii a ?iaioo iaa?ieiai/ieo
aiaeaeieaiue Oa?eianueei? oa Iieoaanueei? iaeanieo eeiii/ieo eiea?aiue,
iinueeeo eiea?aiue i.Oa?eiaa, oeaio?aeueieo ?aeiiieo eiea?aiue
Oa?eianueei? iaeano?, a oaeiae o iaa/aeueiee i?ioean eaoaae? ia?aiaeo
oai?ia Oa?eianueeiai aea?aeaaiiai iaaee/iiai oiiaa?neoaoo oa
Oa?eianueeiai iinoeoooo aaeineiiaeaiiy eiea?ia.

Iniaenoee aianie o ?ic?iaeo iaoeiaeo ?acoeueoaoia. Aaoi?ii naiinoieii
i?iaaaeaii eeiii/ia, aiioiii/ia, ineoieiai/ia aeineiaeaeaiiy oai?eo ia
OIIE oa aiia?oiii/io oai?iao, a oaeiae ocyoa o/anoue a
aenia?eiaioaeueieo aeineiaeaeaiiyo oaa?ei c iiaeaeueiei aoa?ineea?icii.
Aeey oiioieaoei? ?acoeueoaoia aeineiaeaeaiue oa eiii’thoa?ii? ia?iaee
iioi?iaoei? ?ic?iaeaia i?ia?aia aeiaaiinoeee oa aeeoa?aioeieii?
aeiaaiinoeee AeA. Caeieniaii aiaeic aiiaia?aaoe/ieo, iae?iaoii?aeueieo
oa aaaaoaoeaieo ii?ooaiue o caeaaeiinoi aiae noaaei? aeenoee?eoeyoi?ii?
aioeaoaeiiaoi?, aaiiaeeiaii/ieo iieacieeia, no?oeoo?ieo oa
ooieoeiiiaeueieo ciii aieiaiiai iiceo i eeiii/ieo neiae?iiia
caoai?thaaiiy. I?iaaaeaia oa?aiaaoe/ia ei?aeoeiy iaoaaiei/ieo ?iceaaeia
c ii?iaiyeueiei aiaeicii aoaeoeaiinoi iaaeeeaiaioicii? oa
iaiaaeeeaiaioicii? oa?aii? oa i?iniaeoeaia niinoa?aaeaiiy ca oai?eie c
?icieie aa?iaioaie aaaaoaoeaii? ?aaoeyoei? i?ioyaii 5-8 ?ieia.

Ai?iaaoeiy ?iaioe. ?acoeueoaoe i?iaaaeaieo aeineiaeaeaiue iiaiaeiieaii
oa iaaiai?aii ia I c’?caei aa?iioieiaia i aa?iao?ia Oe?a?ie
(Aeiii?iiao?ianuee, 1988); V Ananithciiio c’?caei aa?iioieiaia i
aa?iao?ia (Oaieini, 1988); VIII c’?caei iaa?iiaoieiaia, ineoiao?ia i
ia?eieiaia Oe?a?ie (Oa?eia, 1990); Anaoe?a?inueeie eiioa?aioei?
“Iaiaaeeeaiaioicii iaoiaee eieoaaiiy” (Oa?eia, 1991); iiaeia?iaeiie
eiioa?aioei? “Eiii’thoa?: oaoiiea, oaoiieiaiy oa caei?ia’y” (Oa?eia,
1995); iiaeia?iaeiie iaoeiai-i?aeoe/iie eiioa?aioei? “Ethaenueeee oaeoi?
o ieoaiiyo aaciaee” (Oa?eia, 1996); I Iaoeiiiaeueiiio Eiia?ani
iaa?ieiaia, ineoiao?ia i ia?eieiaia Oe?a?ie (Oa?eia, 1997); II
iiaeia?iaeiiio eiia?ani c iioaa?aoeaii? aio?iiieiai? (Aiiieoey, 1998);
ia ?aaiiiaeueieo, iaeanieo, iinueeeo iaoeiai-i?aeoe/ieo eiioa?aioeiyo,
caniaeaiiyo Oa?eianueeiai iaeaniiai oiaa?enoaa iaa?ieiaia (1988-1998).

Ioaeieaoei?. Iniiaii iieiaeaiiy aeena?oaoei? iioaeieiaaii a 35
ae?oeiaaieo ?iaioao, c ieo 15 o oaoiaeo iaoeiaeo aeaeaiiyo, c yeeo 10
naiinoieieo.

No?oeoo?a oa ianya aeena?oaoei??. Aeena?oaoeiy aeeeaaeaia ia 465
noi?iieao iaoeiiieniiai oaenoo i neeaaea?oueny ic anooio, iaeyaeo
eioa?aoo?e, naie ?icaeieia aeanieo aeineiaeaeaiue, caeeth/ii? /anoeie,
aeniiaeia, i?aeoe/ieo ?aeiiaiaeaoeie oa aeiaeaoeia. ?iaioa iethno?iaaia
73 oaaeeoeyie, 35 ?enoieaie oa eeiii/ieie i?eeeaaeaie. Nienie
aeei?enoaii? eioa?aoo?e neeaaea?oueny c 459 aeaea?ae, c yeeo 276
a?o/eciyieo oa e?a?i aeeaeiueiai ca?oa?aeaey ? 183 iiicaiieo.

CIINO ?IAIOE

Caaaeueia oa?aeoa?enoeea niinoa?aaeaiue i iaoiaee aeineiaeaeaiiy.

Iniiaith aeena?oaoeieii? ?iaioe iineoaeeee iaoa?iaee eiiieaeniiai
ianoaaeaiiy 803 oai?eo, yei a caeaaeiinoi aiae caaaeaiue aeineiaeaeaiiy
aoee ?iciiaeieaii ia aeaeieueea a?oi: 1) aeey anoaiiaeaiiy iniaeeainoae
aiiaia?aaoe/iiai, iae?iaoii?aeueiiai oa aaaaoaoeaiiai aiiainoaco
aeineiaeaeaii 299 iaoei?ioia AeA ?iciiai aaiaco i noaaeie (caiaeii c
eeaneoieaoei?th N.A.Oiiaeoa,1985); 2) aeey aea/aiiy iaoaiiciia aieeao
aaaaoaoeaii? ia?aiai? nenoaie ia ia?aaia a?ia?oii?/ii? oai?iae (AO) i
oi?ioaaiiy OIIE i?e a?oa?iaeueiie aiia?oaici? (AA) ianoaaeaii 258
iaoei?ioia, c yeeo 99 oai?eo ia a?aie/io a?oa??aeueio a?ia?oaic?th
(/ieiaiee aieii aiae 18 aei 36 ?ieia); 78 – ia AO 1 no.(/ieiaiee aieii
aiae 28 aei 45 ?ieia); 81 – ia AO II no. (/ieiaiee aieii aiae 43 aei 58
?ieia) caiaeii c eeaneoieaoei?th AIIC (1996); a?oio ii?iaiyiiy neeaee 75
i?aeoe/ii caei?iaeo /ieiaieia aiaeiiaiaeiiai aieo; 3) aeey aecia/aiiy
iaeaieueo ni?eyoeeaeo oa iani?eyoeeaeo oeiia aaaaoaoeaii? ?aaoeyoei?,
aiiaia?aaoe/ii-aaaaoaoeaieo i aiiaia?aaoe/ii-iae?iaoii?aeueieo
niiaaiaeiioaiue i?iaaaeaia i?iniaeoeaia niinoa?aaeaiiy i?ioyaii 5-8
?ieia ca 246 oai?eie, ui no?aaeaeaee ia neiae?ii aaaaoaoeaii? aeenoiii?
?iciiai aaiaco: eiinoeoooeieii coiiaeaiee (41 iaoeicio), yeee aeiee ia
oei aiioeieiiai no?ano (67 iaoei?ioia) /e OIIE (138 iaoei?ioia); 4)
iniaeeainoi aiiaia?aaoeee oa aaaaoaoeaii-iae?iaoii?aeueieo
niiaaiaeiioaiue aeineiaeaeaii o 293 inia c iniiaieie oaeoi?aie ?eceeo
oea?aa?iaaneoey?ii? iaoieiai? (aeeneiiii?ioa?iaii?th, niaaeeiainoth,
iaoyaeaiith na?oeaai-noaeeiieie caoai?thaaiiyie, aiiiaeeiaii?th) aac
eeiii/ieo i?iyaia caoai?thaaiiy. A oei eeiii/ii a?oie aaieoee /ieiaiee o
aioei aiae 17 aei 30 ?ieia (75, 85 i 41 aiaeiiaiaeii); ianoaaeaii oaeiae
35 inia, yei aaee aeoeaiee niinia aeeooy (aieii aiae 19 aei 30 ?ieia) oa
54 iniae oiai ae aieo, ui caciaaaee o?iii/iiai aiioeieiiai no?ano. Oei
a?oie aoee noi?iiaaii a i?ioeani aiiaeaiiieiai/ieo aeineiaeaeaiue, yei
i?iaiaeeeenue IAeI oa?aii? ii. I.Ae.No?aaeanea ia aaeeeeo eiioeiaaioao
nooaeaioia oa?eianueeeo AOCia, iaoeiaeo i?aoeiaieeia IAeI, a oaeiae i?e
ne?eiiiaiai aiaee?eoi? /ieiai/i? iiioeyoei? 20-54 ?ieia o
Aeca?aeeinueeiio ?aeiii i.Oa?eiaa.

Aenia?eiaioaeueiee aoa?ineea?ic aiaeoai?thaaany ia 20 noaoaai c?ieeo
e?ieeeao-naioeyo ii?iaee Oeioeea c aeei?enoaiiyi caaaeueiii?eeiyoi?
oieanoa?eiiai? iiaeae? (I.I.Aii/eia, A.I.Eeeiia,1976). Eiio?ieueio a?oio
neeaee 12 ?ioaeoieo oaa?ei.

Iaoiaeeee aeineiaeaeaiiy, yei aeei?enoiaoaaeeny a aeaiie ?iaioi,
aeioeieueii ?iciiaeieeoe ia /ioe?e a?oie.

Ia?oa a?oia aeicaieeea aa?eoieoaaoe AeA ca aeiiiiiaith eeiii/iiai
ianoaaeaiiy c aeei?enoaiiyi niaoeiaeueii ?ic?iaeaieo ea?o i
eiii’thoa?ii? i?ia?aie aeiaaiinoeee, iino?oiaioaeueieo aeineiaeaeaiue
aaiiaeeiaiiee oa aecia/aiiy no?oeoo?ii-ooieoeiiiaeueieo oa?aeoa?enoee
aieiaiiai iiceo. Noai oea?aa?aeueii? aaiiaeeiaiiee ioeiithaaany
?aaeiiioeeiaeieie oa oeueo?acaoeiaeie iaoiaeeeaie. Niiaaiaeiioaiiy
oaeaeeinoae eiiieiiai iiceiaiai e?iaioieo a a?oa?iaeueiiio i aaiiciiio
?onei, a oaeiae caaaeueiee /an oea?aa?aeueiiai e?iaioieo aecia/aee ca
aeiiiiiaith ?aaeiioee?eoeiaioeaoaeia?ai (?OeAA) ia o?eeaiaeueiiio
?aaeiia?aoi “Aaiia” (OI?) c aeei?enoaiiyi iaoaiaoe/ii? ia?iaee
(I.I.Ieeeiaiei, I.A.Aieioei c niiaaao.,1984). Ioeiieo e?iaioieo a
ie?aieo iiceiaeo a?oa?iyo i?iaiaeeee c aeei?enoaiiyi aeno?a- oa
o?aine?aiiaeueii? aeiiea?ia?aoi? (OEAe) ia aia?aoi “Sonodop-8000” oi?ie
Sonotechnik (Iiia//eia). Oeaio?aeueia aaiiaeeiaiiea aea/aeany ca aeaieie
oao?aiiey?ii? a?oaeii? ?aia?aoi? ia aeaieaiaeueiiio ?aiieaoeciia?aoi
?IA2-02 (C.Kubicek,1966; TH.O.Iooea?ue,1977). Oea?aa?aeueia
iae?iaeeiaiiea aea/aeany ca aeiiiiiaith aicoaeueiiai aiaeico AAA, a
oaeiae oiiinaeaeoeaiiai ea?ooaaiiy ia 16-eaiaeueiiio
aeaeo?iaioeaoaeia?aoi c aeei?enoaiiyi i?ia?aie “Neurotools”. Aeey
aicoaeicaoei? no?oeoo?ieo ciii aieiaiiai iiceo aeei?enoiaoaaany iaoiae
eiii’thoa?ii? oa iaaiioii-?aciiainii? oiiia?aoi? ca aeiiiiiaith EO ST
MAX General Electric Med. Syst, ? I?O “Ia?ac – 1”.

Ae?oaa a?oia iaoiaeee aeicaieeea ioeiieoe aiiaia?aaoe/iee aiiainoac o
oai?eo ia OIIE oa a aenia?eiaioaeueieo oaa?ei. Noai ieenethaaeueiiai
oinoi?eethaaiiy oa caaacia/aiinoue aia?ai?th o iaoei?ioia ioeiithaaeeny
ca aiinoii aaeaiieiaeo ioeeaioeaeia a ia?eoa?e/i?e e?iai iaoiaeii
oiieioa?iai? o?iiaoia?aoi? (?.A.sseooaaa, E.?.I?eiaa, 1974). Aeey
ioeiiee noaio iaoaaieicio a iaioicioinoaoiiio oeeeei ia?aoai?aiiy
aetheice aea/aeanue aeoeaiinoue aetheici-6-oinoaoaeaaiae?iaaiace
(A-6-OAeA) niaeo?ioioiiao?e/iei niiniaii. I?i iioaineaiinoue i?ioeania
aiaa?iaiiai aeieieico noaeeee ia iiaenoaai aeoeaiinoi eeth/iaiai
oa?iaioo – eaeoaoaeaaiae?iaaiace (EAeA), a oaeiae oa?iaioia aeueaeieace
(AAe), oinoio?oeoieiiace (OOE), aaenieiiace (AE) a ieacii e?iai oa
a?eo?ioeeoao ca aeiaeaieie oiioieiaaieie iino?oeoeiyie. Icioa?iaioiee
niaeo? EAeA aea/aany iaoiaeii aeaeo?ioi?aco a aaa?iciiio aaeaai
(I.A.Aa?iai ci niiaaao.,1982). sse iieaciee aiiieni? aecia/aany aiino o
ne?iaaooei e?iai eiioeaaiai i?iaeoeoo aeieieico – eaeoaoo oa i?iiiaeiiai
i?iaeoeoo – ii?oaaoo ca aiceiaoe/ieie iaoiaeeeaie, iienaieie
I.I.I?ioi?iaith (1982). ?iaaiue aetheice a ne?iaaooei e?iai aecia/aany
noaiaea?oiei niiniaii. Noai ieneaeaioii? i aioeieneaeaioii? nenoai
ioeiithaaany ca iieacieeaie aiinoo aei?iiaeo eii’thaaoia (AeE),
iaeiiiaiai aeiaeueaeaaiaeo (IAeA), SH-a?oi, aeooaoiiio, eaoaeace (Ea),
ia?ieneaeace (I), yei aecia/aeeny noaiaea?oieie aiioiii/ieie
iaoiaeeeaie. ?iaaiue oinoieiiiaeieo o?aeoeie iaia?ai a?eo?ioeeoia
aecia/aany ca iaoiaeii aeaiii?ii? o?iiaoia?aoi? c ?o iaeaioeoieaoei?th
ca noaioa?oieie aecia/ieeaie. Aecia/aiiy ??aiy ia?ea?ieo
iaia?aiica’ycaieo oa?iaio?a i?iaiaeeeiny ca aeiaeaieie oi?o?eiaaieie
?ino?oeoe?yie. Aeey oa?aeoa?enoeee aia?aaoe/iiai iaiiio a aieiaiiio
iiceo aenia?eiaioaeueieo oaa?ei aea/aeenue iioioiiae?iaeueii oa?iaioe
oeeeeo o?eea?aiiiaeo eeneio: noeoeeiaoaeaaiae?iaaiaca (NAeA),
aeueoa-eaoiaeooa?aoaeaaiae?iaaiaca, oeeo?aoneioaca oa
aeooaiaoaeaaiae?iaaiaca (aeooaiao-AeA) niaeo?ioioiiao?e/iei iaoiaeii
(I.I.I?ioi?iaa,1982), oa?iaioe aiaa?iaiiai aeieieico (AAe, EAeA, OOE,
AE) oa aiino eaeoaoo i ii?oaaoo a ei?i aaeeeeo iiaeoeue, aiiioaeaioni,
noiaao?i iiceo, a oaeiae o ne?iaaooei, ieacii i a?eo?ioeeoao e?iai
aecia/aee oioieiei?eiao?e/iei iaoiaeii (A.N.Anaoiaii,1969). Aiino
i?iaeoeoia IIE o oeaieii iiceo aea/aee niaeo?ioioiiao?e/ii (A.I.I?aoia,
1978). Aecia/aiiy aeoeaiino? Na-AOOace i?oioiiae??e i?iaiaeeee
oioieiei?eiao?e/iei niiniaii.

O?aoy a?oia iaoiaeee ioeiithaaea noai iae?iaoii?aeueieo nenoai ia iniiai
aecia/aiiy a ieacii e?iai aiinoo i?inoaii?aeia (noaaieueiiai iaoaaieioo
i?inoaoeeeeiio 6-eaoi-IAF1, noaaieueiiai iaoaaieioo o?iiaienaio A2
Tx-B2, i?inoaaeaiaeeiia IAA1 , IAF2 ) ?aaeiiiioiieiai/iei iaoiaeii.
Aeiaiaa aene?aoeiy c ii/ith aae?aiaeiio (A) oa ii?aae?aiaeiio (IA)
aea/aeany niaeo?ioethi?ia?aoi/iei iaoiaeii (I.O.Iaoeiia,1976). ?iaii
iae?iiaaeiaoi?ieo aiiiieeneio, aiiaaiieo iiiiaiiiia oa ?oiio
iiia?aaeieeia aecia/aeeny iaoiaeii iiiiiaiiiii? i eieiieiai?
o?iiaoia?aoi? c aiaeicii ?oiio niaeo?ia ca eaeia?iai/ieie e?eaeie.

Ieaciiai iieacieee eiiiaeiiai iaiiio: caaaeueiee oieanoa?ei (ON),
o?eaeioea?eaee (OA), ON eiiii?ioa?aeia iecueei? aonoeie (ONEIIA), ON
eiiii?ioa?aeia aeniei? aonoeie (ONEIAA) aecia/aeeny c aeei?enoaiiyi
oa?iaioieo iaai?ia ca aeiaeaieie iino?oeoeiyie; aeey aecia/aiiy
niiaaiaeiioaiiy ?icieo eeania EI ?ic?aoiaoaaee eiaoioei?io aoa?iaaiiinoi
(EA) ca A.I.Eeiiiaei (1984).

*aoaa?oa a?oia iaoiaeee aeei?enoiaoaaeany aeey aecia/aiiy iniaeeainoae
aaaaoaoeaii? ?aaoeyoei?. Aeineiaeaeoaaeeny noa’?eoeaii e ia’?eoeaii
aaaaoaoeaii neiioiie ca niaoeiaeueieie noaiaie, a oaeiae aaaaoaoeaiee
oiion, aaaaoaoeaia ?aaeoeaiinoue (A?), aaaaoaoeaia caaacia/aiiy
oice/ii?, ?icoiiai? oa aiioeieii? aeiyeueiinoi (ACAe) (I.I.Aaei ci
niiaaao.,1991). E?ii oiai, aaaaoaoeaii ooieoei? ioeiithaaeeny ca
iaoiaeii aa?iaoeieii? iioa?aaeiiao?i? (?.I.Aa?anueeee, 1988).

Noaoenoe/ia ia?iaea ?acoeueoaoia aeineiaeaeaiiy i?iaaaeaia ca
aeiiiiiaith no/anieo iaoiaeia iaoaiaoe/iiai aiaeico ia IAII c
canoinoaaiiyi iaeaoo i?eeeaaeieo noaoenoe/ieo i?ia?ai “Statgraf”.

?ACOEUeOAOE AeINEIAeAEAIUe OA IO IAAIAI?AIIss

Aiiaia?aaoe/iee aiiainoac aeineiaeaeaii o 299 oai?eo ia OIIE o aioei
aiae 39 aei 79 ?ieia. ?c ieo ii/aoeiaa noaaeiy AeA aeyaeaia o 117
oai?eo, na?aaeiie aie yeeo neeaa 45 ?ieia, II noaaeiy – o 113 iaoei?ioia
(na?aaeiie aie – 57 ?ieia), III – o 69 inia (na?aaeiie aie – 64 ?iee).
A?oio ii?iaiyiiy neeaee 39 caei?iaeo inia aiaeiiaiaeiiai aieo. Na?aae
eeiii/ieo neiae?iiia o oai?eo anio noaaeie iae/anoioa cono?i/aeeny
iaa?iciiiaeiaiee oa neiae?ii aaaaoaoeaii? aeenooieoei?. A i?ioeani
i?ia?anoaaiiy caoai?thaaiiy eieueeinii oa yeinii c?inoaee aeenniiii/ii
(a I noaaei? – o 49,6%; a II – o 77,8%; a III noaaei? – o 97%
aeiaaeeia), aanoeaoey?ii-aoaeoe/ii (o 67,5%; 84,9%; 81% aeiaaeeia
aiaeiiaiaeii), ii?aiiaeii (o 58,1%; 71,6%; 71% aeiaaeeia, i?e/iio o II
noaaei? c ieo o 42% iaoei?ioia, a a III noaaei? o 60,6% – ia?ace),
iioaeaeooaeueii-iianoe/ii ii?ooaiiy (o 72,6%; 73,4% oa 82,6% aeiaaeeia
aiaeiiaiaeii), i?e/iio a III noaaei? eiaiioeaii ii?ooaiiy o 30%
aeinyaaee ?iaiy aeaiaioei?. A AeA III noaaei? o 17,4% oai?eo c’yaeyany
aiiinoaoe/iee neiae?ii, o 10% – inaaaeiaoeueaa?iee, o 18,8% –
aeno?aii?aiiaeiee. O 4 oai?eo aeiaaiinoiaaia oai?iaa Aiinaaiaa?a.

?acoeueoaoe aea/aiiy oea?aa?aeueii? aaiiaeeiaiiee ca aeiiiiiaith ?OeAA
iieacaee, ui c i?ia?anoaaiiyi OIIE iiaeaeuoaaany caaaeueiee /an
iiceiaiai e?iaiiaiao a 1,64 ?aca a ii?iaiyiii c eiio?ieueiith a?oiith,
i?e/iio a I coaaei? iiaeiaaeaiiy aiaeaoaaeiny ia?aaaaeii ca ?aooiie
eaiiey?ii? oa aaiicii? oac, a a III noaaei? – aianeiaeie ii?ooaiiy
oeaio?aeueii? aaiiaeeiaiiee (aiiieiiaoe/iee oei e?iaiiaiao, iiaeaeuaiiy
caaaeueiiai ia?eoa?e/iiai noaeeiiiai iii?o (CINI)). Ia OEAe oei i?ioeane
ciaoiaeeee aiaeia?aaeaiiy a cieaeaiii na?aaeiuei? oaeaeeinoi e?iaiiaiao
a 1,8 ?aca a ea?ioeaeiiio oa a 2 ?ace a aa?oaa?iaaciey?iiio aanaeiao, a
oaeiae o iiaeaeuaiii iiaeaeno iii?o i cieaeaiii iiaeaeno ?aaeoeaiinoi
oea?aa?aeueieo noaeei.

Oea?aa?aeueia iae?iaeeiaiiea oa?aeoa?ecoaaeany cieaeaiiyi aiieiooaee i
iiooaeiinoi niaeo?ia aeueoa-, aaoa-?eoiia oa c?inoaiiyi aiieiooaee i
iiooaeiinoi niaeo?ia oaoa- i aeaeueoa-?eoiia c iiyaith eiaoioei?ioia
iiaeiiaeoeaai? aneiao?i?. C i?ia?anoaaiiyi OIIE caeaaeaeoaaeany
?aaiiia?ia aiaeiiiiinoue ?eoiia oa cieaeoaaeany ?aaeoeaiinoue ia
ooieoeiiiaeueii i?iae.

Iae?iaicoaeicaoeiy no?oeoo? aieiaiiai iiceo oai?eo ia AeA aeyaeea
iai?yii iciaee eiai ao?ioi? o aeaeyaei aioo?ioiuei? oa ciaiioiuei?
aiae?ioeaoaei?, ae?aaeaiinoue yeeo c?inoaea c i?ia?anoaaiiyi OIIE. Oae,
oe?eia ia?aaeiueiai ?iao aieiaiai oeoii/ea ceiaa c?inoaea a o?ao?e
noaae?? 1,9 ?aca, ni?aaa – a 1,6 ?aca; oeaio?aeueiiai aiaeaeieo eiaiai
oeoii/ea – a 1,8 ?aca, i?aaiai – a 1,6 ?aca, ui naiae/eei i?i
oaiaeaioeith aei aieueoiai ?icoe?aiiy oeoii/eia ceiaa. Oe?eia o?aoueiai
oeoii/ea c?inea c 5,0 0,86 ii a ia?oie noaaei? aei 7,0 0,84 a o?aoie
(p0,05), neieueee
aiae nooiaiy ii?ooaiue aaiiaeeiaiiee. Oae, aiino AOO i?e AeA ? no.
cieaeoaaany eeoa ia 3%, i?e AeA ?? no. aaea ia 28%, a a ??? no. – ia 48%
i?e iinoieiiio c?inoaiii iiaeaeno AAeO/AOO, ui naiae/eei i?i ia?inoaiiy
aeenaaeaino iaiiio iae?ia?ai/ieo niieoe c iineeaiiyi oea?aa?aeueii?
ioaii? (oaae.1). Ca’ycie aia?aaoe/iiai aeaoioeeoo c iiaeeaeaiiyi
aaiiaeeiaii/ieo ii?ooaiue iiaeoaa?aeaeoaaany e?i?eieie ?aa?anieieie
caeaaeiinoyie iiae aiinoii AOO i na?aaeiueith oaeaeeinoth iiceiaiai
e?iaioieo ca aeaieie OEAe, a oaeiae caaaeueiei /anii oea?aa?aeueiiai
e?iaioieo ca aeaieie ?OeAA:

Y = 151,4 7,9 X1

Y = 925,2 25 X2 ;

aea – Y – ?iaaiue AOO, O1 – na?aaeiy oaeaeeinoue e?iaioieo
ca aeaieie OEAe; O2 – caaaeueiee /an iiceiaiai e?iaioieo.

Io?eiaii noaoenoe/ii caeaaeiinoi naiae/eee i?i iiceoeaiee eiiieiee
?aa?an?eiee ca’ycie iiae aiinoii AOO i na?aaeiueith oaeaeeinoth
e?iaiiaiao oa iaaaoeaiee eiiieiee ca’ycie c caaaeueiei /anii iiceiaiai
e?iaioieo. I?e/iio iaeieae/ee aiino AOO niinoa?iaaany i?e iiaeiaaeaiii
eaiiey?ii? oace e?iaioieo, i?i ui naiae/ea iaeaeuee eiaoioei?io
ei?aeyoei? ?iaiy AOO oa o?eaaeinoi aeacaii? oace (r = -0,45) a
ii?iaiyiii c eiaoioei?ioaie (r = -0,36; -0,34; -0,33), yei iia’ycothoue
?iaaiue AOO i aiaeiiaiaeii o?eaaeinoue oace I, oace 1,oace 3, oiaoi
i?eoieo e?iai ii iaaino?aeueieo a?oa?iyo, iio?ae?aiiaeueieo a?oa?iyo oa
aiaeoieo ii aaiao (p0,05). O ii/aoeiaie noaaei? OIIE aiaeaoaaeany
oaeiae aeoeaaoeiy, a c i?ia?anoaaiiyi aeenoee?eoeyoei? cieaeaiiy
aeoeaiinoi iaioiciiai oeeeeo ia?aoai?aiiy aoaeaaiaeia, ui ciaeoei
aiaeia?aaeaiiy o aiaeiiaiaeiie aeeiaiioei aetheici-6-oinoaoAeA (aeea.
oaae. 1).

O oai?eo c ?icaeoeii OIIE aeyaeaia c?inoaiiy aiinoo eaeoaoo oa ii?oaaoo
a ne?iaaooei e?iai. A ? no. AeA ?o ?iaaiue iiaeaeuoaaany ia 47,8% i
71,2%; a ?? no. – ia 65,5% i 84,1% aiaeiiaiaeii, a a ??? no. aiino
eaeoaoo ciaiooaaany ia 24,3%, a ii?oaaoo ia 23% ii aiaeiioaiith aei
iiia?aaeiuei? noaaei?. Eiaoioei?io ii?oaao/eaeoao iiaeaeuoaaany
aiaeiiaiaeii a eiaeiie ianooiiie noaaei? a 1,16; a 1,28; a 1,31 ?ace, ui
oaeiae naiae/eei i?i iiaeeaeaiiy aeieoaaiiy aa?iaieo oeeeeia ieeneaiiy
aetheice. Aiino aetheice a e?iai ia ii/aoeiaeo noaaeiyo o?iii/ii?
iiceiai? aeenoee?eoeyoei? aeinoiai?ii ia ciiithaaany, eeoa a o?aoie
noaaei? OIIE niinoa?iaaeanue oaiaeaioeiy aei aiia?aeieaii?.

Oaeei /eiii, i?iaiaeiei i?iyaii aiiaia?aaoe/iiai aeenaaeaino ia anio
aoaiao OIIE ? aia?aaoe/iee aeaoioeeo, yeee ?icaeaa?oueny aianeiaeie
i?eaii/aiiy i?ioeania ieenethaaeueiiai oinoi?eethaaiiy. A ii/aoeiaie
noaaei? aeenoee?eoeyoei?, ye eiiiainaoi?ia ?aaeoeiy o aiaeiiaiaeue ia
cieaeaiiy aa?iaiiai aeieieico, aeoeaico?oueny iaioicioinoaoiee oeyo
ia?aoai?aiiy aetheice oa aiaa?iaiee aeieieic, ui aaaaea?oueny oeiiaei
iaoieiai/iei i?ioeanii i?e aiiieni? (A.I.E?eaeaiianueeee, 1997).
Aeoeaaoeiy aiaa?iaiiai aeieieico c iaeiiai aieo ? aaeaioaoeieiei
iaoaiiciii aei aiiieni?, c ae?oaiai aieo i?eaiaeeoue aei iaeiie/aiiy
eaeoaoo i ?icaeoeo eaeoaoeeaeico E??i oiai, i?aeaeuaiiy ??aiy eaeoaoo oa
i??oaaoo noeioeth? neioac oieanoa?eio oa aee?ieo eeneio (R.A.Harris,
1985; V.Bartley, 1986). Oea iiaea iani?eyoeeai iicia/eoeny ia ia?aa?ao
aoa?ineea?ico noaeei aieiaiiai iiceo, i?i ui na?ae/eoue a?eyaeaiee
iiceoeaiee ei?aeyoe?eiee ca’ycie i?ae ??aiai eaeoaoo ? oieanoa?eiii (r =
+0,56, p 0,05), oi a ae?oa?e noaae?? iaeaoaeaa?ae?iaaiaca ? e?aaoeioinoie?iaca
i?aeaeuothoueny a 1,3 ?aca, ania?aa?iiaa o?ainai?iaca – a 2 ?ace,
aeai?iiaa o?ainai?iaca – a 2,2 ?aca, -aeooaiao-o?ainoa?aca – a 1,6 ?aca,
-a?ae?ieneaooe?aoaeaa?ae?iaaiaca – a 1,4 ?aca, eoaeia oinoaoaca – a 2,1
?aca (?0,05) oa aiiiaeeiaii?th (p>0,01). A a?oii c
o?iii/iei aiioeieiei no?anii niinoa?iaaeiny ai?iaiaeia c?inoaiiy aiinoo
eaeoaoo (?

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