?INOEOOO IAAe?AO???, AEOOA?NOAA OA A?IAEIEIA??
AEAAeAI?? IAAeE*IEO IAOE OE?A?IE
O?IEIA NA?A?E NA?A?EIAE*
OAeE 618.177 – 072.1 – 072.7 – 08 + 616 – 036.82 + 612.018
Ae?AAIINOEEA, E?EOAAIIss OA ?AAA?E?OAOe?ss OAI?EO
C II?AeIAIITH AE?II*ITH IAIE?AeI?NOTH
14.01.01 -Aeooa?noai ? a?iaeieia?y
Aaoi?aoa?ao
aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy
eaiaeeaeaoa iaaee/ieo iaoe
Ee?a-1999
Aeena?oaoe??th ? ?oeiien.
?iaioa aeeiiaia a Aeiiaoeueeiio aea?aeaaiiio iaaee/iiio oi?aa?neoao? ?i.
I. Ai?ueeiai IIC Oe?a?ie.
Iaoeiaee ea??aiee:
aeieoi? iaaee/ieo iaoe, i?ioani?, *aeea Aieiaeeie? Ee?eeiae/,
Aeiiaoeueeee aea?aeaaiee iaaee/iee oi?aa?neoao ?i. I.Ai?ueeiai IIC
Oe?a?ie, caa?aeoaa/ eaoaae?e aeooa?noaa, a?iaeieia?? oa ia??iaoieia??
oaeoeueoaoo i?neyaeeieiiii? ina?oe.
Io?oe?ei? iiiiaioe:
-aeieoi? iaaee/ieo iaoe, i?ioani? ?aaithoa E?ae?y ?aai?aia, ?inoeooo
iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie, caa?aeoth/a
a?aeae?eaiiyi ?aaa?e?oaoe?? ?ai?iaeoeoeaii? ooieoe?? ae?iie;
-aeieoi? iaaee/ieo iaoe, i?ioani? A?oaiiiia Aieiaeeie? Na?a?eiae/,
Iaoe?iiaeueiee iaaee/iee oi?aa?neoao ?i.I.I.Aiaiiieueoey IIC Oe?a?ie,
caa?aeoaa/ eaoaae?e aeooa?noaa oa a?iaeieia??.
I?ia?aeia onoaiiaa: Ee?anueea iaaee/ia aeaaeai?y i?neyaeeieiiii? ina?oe
?i.I.E.Ooieea IIC Oe?a?ie, eaoaae?a aeooa?noaa oa a?iaeieia?? ? 3.
Caoeno aeena?oaoe?? a?aeaoaeaoueny “23 ” aa?aciy 1999 ?ieo i ?C00
aiaeei? ia can?aeaii? niaoe?ae?ciaaii? a/aii? ?aaee Ae 26.553.01 ii
caoenoo aeena?oaoe?e ia caeiaoooy iaoeiaiai nooiaiy aeieoi?a iaoe ca
niaoe?aeueiinoyie “Iaae?ao??y”, “Aeooa?noai ? a?iaeieia?y” i?e ?inoeooo?
iaae?ao???, aeooa?noaa oa a?iaeieiae AII Oe?a?ie (252050, i.Ee?a,
aoe.Iaio?euenueeiai,8).
C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? ?inoeoooo
iaae?ao???, aeooa?noaa oa a?iaeieia?? AII Oe?a?ie (252050, i.Ee?a,
aoe.Iaio?euenueeiai,8).
Aaoi?aoa?ao ?ic?neaiee “18” ethoiai 1999 ?ieo.
A/aiee nae?aoa?
niaoe?ae?ciaaii? a/aii? ?aaee
Eaaoi?ia E.A.
CAAAEUeIA OA?AEOA?ENOEEA ?IAIOE
Aeooaeuei?noue i?iaeaie. *anoioa aacie?aeieo oetha?a neeaaea? 15-20%
oa ia? oaiaeaioe?th uiaei c?inoaiiy (A.E. Eoeaeia, O.A. Ianyiieeiaa,
1997; E.E. Eaaithoa, E.O. THiaea, 1990). Ca aeaieie AIC, iaie?aeiee
oetha aieeaa? ia aeaiia?ao?/i? iieacieee a?eueo iaaaoeaii, i?ae
iaaeiiooaai?noue aaa?oiino? oa ia??iaoaeueia iaoieia?y ?acii (O. A.
Oaooaoiaa, 1997).
Nooo?aei aaeueiii uiaei oaeaeeiai oa oi/iiai anoaiiaeaiiy i?e/eie
aacie?aeiino? a oetha? ? a?aenooi?noue aeioaia? niaoe?aeueieo
noaiaea?oeciaaieo i?ia?ai ianoaaeaiiy, ui aeeth/athoue iaiao?aeiee iaa??
ae?aaiinoe/ieo oano?a ?c oeac?aeith iine?aeiaiino? ?oiueiai canoinoaaiiy
a caeaaeiino? a?ae ee?i?/ieo i?iya?a caoai?thaaiiy (A.E. Eoeaeia, O.A.
Ianyiieeiaa, 1997).
*anoi /eiieee aacie?aeiino? ?niothoue ia ?cieueiaaii, a a niieo/aii?
iaeei c iaeiei, iiaaii ae?aaiinoothoueny, ui cieaeo? ?acoeueoaoeai?noue
e?eoaaiiy.
Ca aeaieie AIC, ca?ac iae?/o?oueny iiiaae 22 /eiieea ae?ii/i?
iaie?aeiino?. *enaeuei?noue oaeoi??a, ui aeeeeeathoue eiai, na?ae/eoue
i?i ??ciiia?ooy iaoieia?/ieo i?ioean?a o ?ai?iaeoeoeai?e nenoai?; oea
oneeaaeith? ae?aaiinoeeo, iniaeeai oiae?, eiee iaiao?aeii aeeeth/eoe
ae?oai?yaei? oa c’ynoaaoe iniiai? /eiieee. I?e oeueiio a eiaeiiio
eiie?aoiiio aeiaaeeo /eiieeii iaie?aeiino? iiaea aooe ia iaeei, a
aeae?eueea /eiiee?a.
Eaia?ineii?y ona a?eueo caoiieth? iiceoe?? a ?ai?iaeoeoieia??. O
e?oa?aoo?? iaaiai?ththoueny ie?ai? i?iaeaie eaia?ineii?/ii?
ae?aaiinoeee: ii?oi-ooieoe?iiaeueiiai noaio y?/iee?a i?e aacie?aeiino?
(N.A. Oou?ia, 1990; ?.A. ?iaeeeia, I.I.?na?a, 1994), aacie?aeiino?
iaa?aeiiiai aaiaco (A.I. Eoeaoia, 1989), o aecia/aii? noaio iaoeiaeo
o?oa ( O.ss. Ioaie/ieeiaa, A.N. Aania?ia ? niaao. 1991; E.TH. Ia?eieeia,
E.I. Ia?eieei, A.A. Eeueeiuo, 1995), o ae?aaiinoeoe? ? e?eoaaii? i?e
iaeeo oi?iao aiaeiiao??ico (I.TH. Ei?ooiia, 1993; I.E. Aieeia, 1996), o
ae?aaiinoeoe? o?oaii-ia??oiiaaeueii? aacie?aeiino? oeai?ae?eii?
ao?ieia?? ( I.I. Iiaaaeeineee, A.A. Eoae?eia, 1994; E.A. Oaiaeaaaa, A.I.
Caeaiianeee, I.A. Aioeia, 1995), a ianoaaeaii? ? e?eoaaii? ae?iie ?c
o?eaaeith aacie?aei?noth, iaoiiaeaiith ii?ooaiiyi iaoeyoe?? (A.I.
Eoeaoia, 1995), o ae?aaiinoeoe? oai?iae iie?e?noicieo y?/iee?a (A.N.
Aania?ia, A.E. Eoeaeia, 1995).
I?ioa ?ieue eaia?ineii?? a ae?aaiinoeoe? e iiaoaiiiio e?eoaaii?
ii?aeiaii? aacie?aeiino? a ae?iie aea/aia iaaeinoaoiuei. Aeine?aeaeaiiy
c oeueiai ieoaiiy iaeiia?/i?, ia a?aoiaothoue ??ciiiai?ooy /eiiee?a
aacie?aeiino?, ia aea/ai? iaea?eueo oa?aeoa?i? niieo/aiiy /eiiee?a ?
?oi?e aca?iiee aieea. Eeoa a ?iaio? A.A. Ei?iaoeueei? (1998) A.N.,
Aania?iaa ? A.E. Eoeaeiaa (1995) anoaiiaeaii niieo/aiiy aiaeie?eiii?
aacie?aeiino? (NIEss) c ?ioith iaoieia??th i?aai?a iaeiai oaco:
o?oaii-ia??oiiaaeueiei /eiieeii -o 20%, ia??oiiaaeueiei-o 32%, i?iiith
iaoee-o 6,5%, ciai?oi?i aiaeiiao??icii -o 3,2%. O ?iaio? A. ?. Ea?iaoo ?
?i. (1989) i?e eaia?ineii?? aeyaeee niieo/aiiy 2-o /eiiee?a
aacie?aeiino? a 46% oai?eo, o?ueio oaeoi?ia – o 19% ? /ioe?ueio -o 2%
iaoe??ioie. I?ioa aeai? a ?iaioao noia?a/eea?, ia a?aeaeaathoue ca’yce?a
/eiiee?a i?ae niaith ? ia iai?/athoue eiie?aoi? oeyoe ?oiueiai
iiaoaiiiai iiaeieaiiy.
Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie. Aeena?oaoe?y
aeeiiaia ca?aeii ieaio IAe? IAe? iaaee/ieo i?iaeai n?i’? oa ? o?aaiaioii
eiiieaenii? oaie “ ?ic?iaea iiaeo i?aeoiae?a aei i?io?eaeoeee oa
e?eoaaiiy aacie?aeiiai oethao ” IIC ? aea?ae. ?a?no?aoe?? 0197V002125,
oeo? oaie IE 950605.
Iaoa aeine?aeaeaiiy: ?ic?iaeoe iaoeiai-iaa?oioiaaiee i?aeo?ae uiaei
ae?aaiinoeee ii?aeiaii? iaie?aeiino?, c’ynoaaoe ?ieue oa i?noea
eaia?ineii?? a ianoaaeaii?, o??o?a?/i?e ei?aeoe?? oa oi?ioaaii?
iiaoaiii? ?aaa?e?oaoe?eii? oa?ai?? a ae?iie c aaaaoioaeoi?iith
aaciie?aei?noth.
Caaea/e aeine?aeaeaiiy:
1.Aea/eoe ee?i?/i? iniaeeaino?, ai?iiiaeueiee noaoon oa ii?oieia?/i?
iniaeeaino? aioo??oi?o noaoaaeo i?aai?a ae?iie, ui no?aaeaeathoue ia
ii?aeiaio iaie?aei?noue.
2. Aea/eoe iaea?eueo oa?aeoa?i? niieoee /eiiee?a.
3.?ic?iaeoe aoaie ?aaa?e?oaoe?eii? oa?ai?? a caeaaeiino? a?ae niieoe
/eiiee?a iaie?aeiino? .
4. C’ynoaaoe i?noea oa ?ieue eaia?ineii?? ye iaeaaaeeea?oi? eaiee ui
aei aena?oethaaiiy iniiaiiai oa noiooi?o /eiiee?a aacie?aeiino? oa
e?eoa??? ianyao o??o?a?/iiai ao?o/aiiy i?e oe?e iaoieia??.
Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a ?iaioe. Aena?oeaia ?ieue
i?aai?/ieo oa ooieoe?iiaeueieo /eiiee?a o oi?ioaaii? ii?aeiaii?
iaie?aeiino?, ci?ie ia?aa?ao oa ee?i?/ii? ea?oeie caoai?thaaiiy.
Iaea?aeaea iiaeaeueoee ?icaeoie ae?aaiinoeea ii?oieia?/ieo ci?i
aioo??oi?o noaoaaeo i?aai?a ? ooieoe?iiaeueieo ii?ooaiue o iaoiaaiac?
ii?aeiaii? aacie?aeiino? ia i?aenoaa? eaia?ineii?/iiai aeine?aeaeaiiy ?
ai?iiiaeueiiai ianoaaeaiiy.
Oaeineiiaeaii aeai?eoi ianoaaeaiiy ae?iee, ui aeicaiey? a iaeei?ioo?
oa?i?ie anoaiiaeoe iayai?noue ii?aeiaii? aacie?aeiino?.
Aia?oa ?ic?iaeaia i?ia?aia aeaiaoaiii? ?aaa?e?oaoe?? c aeei?enoaiiyi
?ineeiieo iiio?iiieo i?aia?ao?a (oaiaeai).
I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a ?iaioe.
?ic?iaeaii e?eoa??? ?aiiueiai aeyaeaiiy oai?eo c ii?aeiaiith
aacie?aei?noth, aeei?enoiaoth/e eaia?ineii?th.
Cai?iiiiiaaiee i?aeo?ae aei ianoaaeaiiy iaoe??ioie ?c niieo/aiiyi
/eiiee?a aacie?aeiino? nei?i/o? /an ianoaaeaiiy aei 3-6 i?n. ? aeeeth/a?
noa’?eoeai?noue a iiaoaii?e oa?ai?? neeaaeiiai eiioeiaaioo oai?eo.
Ioe?iea aoaeoeaiino? aoaiii? ?aaa?e?oaoe?? oai?eo ?c ii?aeiaiith
aacie?aei?noth aeicaiey? aeae?eeoe a?oio iaoe??ioie, yeei iieacai?
aeiiii?aei? ?ai?iaeoeoeai? oaoiieia??.
?acoeueoaoe ?iaioe ai?iaaaeaeaii a Aeiiaoeueeiio aea?aeaaiiio
?aa?iiaeueiiio oeaio?? ioi?iie iaoa?einoaa oa aeeoeinoaa, a?iaeieia?/ieo
a?aeae?eaiiyo i?nueeeo e?ea?aiue i.Ai?e?aee, Ia??oiiey, Aeca?aeeinueeo ?
aeeth/aii aei eo?no eaeoe?e ia oaeoeueoao? i?neyaeeieiiii? ina?oe
Aeiiaoeueeiai iaaee/iiai oi?aa?neoaoo.
Iniaenoee aianie caeiaoaa/a. Aeaniee aianie aaoi?a a iaea?aeai?
?acoeueoaoe aeine?aeaeaiiy ? iniiaiei ? iieyaa? a i?aeai??, ianoaaeaii?
oa e?eoaaii? ae?iie c ii?aeiaiith iaie?aei?noth, i?iaaaeaii?
ae?aaiinoe/ii? oa o??o?a?/ii? eaia?ineii??, ai?iiiaeueieo, niiia?ao?/ieo
oa ooieoe?iiaeueieo ianoaaeaiue, aea/aii? aca?iica’yceo ii?oieia?/ieo oa
ooieoe?iiaeueieo /eiiee?a. Aaoi? naiino?eii aiae?coaaa iaea?aeai? aeai?
e noaoenoe/ii ?o ia?iaeya. Aeena?oaio ia nei?enoaany ?acoeueoaoaie oa
?aeayie aaoi??a, ye? aeeeaaeaii a ?nioth/eo ioae?eaoe?yo.
Ai?iaaoe?y ?iaioe. Iaoa??aee aeena?oaoe?? aeiaaaeai? ia ia?o?e
iaoeiai-i?aeoe/i?e i?aeia?iaei?e eiioa?aioe?? “ ?ai?iaeoeoeaia caei?ia’y
n?i’?: i?iaeaie ? oeyoe ?o ??oaiiy” (Ee?a, 1997), ia i?aeia?iaeiiio
eiia?an? “ Aeooaeuei? ieoaiiy ?ioaeoieia?? a aeooa?noa? ? a?iaeieia??”
(Aeiiaoeuee, 1998), ia can?aeaiiyo Aeiiaoeueei? iaeanii? ?aaee ii
?iaeiiiii/?, 1995-1998.
Ioae?eaoe??. Ca oaiith aeena?oaoe?? iioae?eiaaii 9 iaoeiaeo i?aoeue, ?c
ieo: 4 noaoo? a aeo?iaeao, 2 – a ca??ieeao iaoeiaeo i?aoeue oa 3 – a
oacao iaoeiaeo eiioa?aioe?e.
Ianya ? no?oeoo?a aeena?oaoe??. Aeena?oaoe?eia ?iaioa aeeiiaia ia 161
noi??ieao ae?oeiaaiiai oaenoo. Aiia neeaaea?oueny ?c anooio, iaeyaeo
e?oa?aoo?e, iaoa??aeo oa iaoiae?a aeine?aeaeaiiy, /ioe?ueio ?icae?e?a
aeanieo aeine?aeaeaiue, aiae?co oa ocaaaeueiaiiy io?eiaieo ?acoeueoao?a,
aeniiae?a, i?aeoe/ieo ?aeiiaiaeaoe?e oa ia?ae?eo aeei?enoaieo aeaea?ae
e?oa?aoo?e; i?noeoue 36 oaaeeoeue, 20 ?enoie?a, ye? caeiathoue 28
noi??iie. Nienie aeei?enoaieo aeaea?ae i?noeoue 216 iaeiaioaaiue, c ieo
38 – ?iicaiieo aaoi??a oa caeia? 23 noi??iee.
INIIAIEE CI?NO ?IAIOE
Iaoa??aee ? iaoiaee aeine?aeaeaiiy. Aoee ianoaaeai? 120 iaoe??ioie o
a?oe? a?ae 19 aei 38 ?ie?a. O?eaeoeyoue iaoe??ioie i?ney ae?aaiinoe/ii?
eaia?ineii?? iaea?aeoaaee o?aaeeoe?eio eiina?aaoeaio oa?ai?th ? neoaeeee
eiio?ieai (e), 90 iaoe??ioeai iniiaii? a?oie i?iaaaeaii iia?aoeaio
eaia?ineii?th, iaaeae? 46 c ieo iaea?aeaee 1 aoai ?aaa?e?oaoe?eii?
oa?ai?? (1-a i?aea?.), a 44 iaea?aeaee 2-o aoaiio ?aaa?e?oaoe?eio
oa?ai?th (2-a i?aea?.). I?aea?oie iniiaii? a?oie aoee ii??aiyi? ia
o?eueee ca a?eii, o?eaae?noth aacie?aeiino?, oa?aeoa?ii iaino?oaeueiiai
oeeeeo, aea ? ii ii?oieia?/ieo ci?iao iaoeiaeo o?oa, ai?iiiaeueieo
aeine?aeaeaiiyo e?ia? oa ooieoe?iiaeueieo oanoao.
Ianoaaeaiiy i?iaiaeeeenue a a?aeae?eaii? iia?aoeaii? a?iaeieia?? oa
o?ieia?? IAe? iaaee/ieo i?iaeai n?i’? (i. Aeiiaoeuee).
O an?o iaoe??ioie aeine?aeaeoaaee ooieoe?iiaeueiee noai y?/iee?a ia
i?aenoaa? eiiieaeno oano?a ooieoe?iiaeueii? ae?aaiinoeee ( oea?a?eaeueia
/enei ia 7-e, 14-e ? 21-e aei? iaino?oaeueiiai oeeeeo, aei?? aacaeueii?
oaiia?aoo?e). Oeueo?acaoeiaa aeine?aeaeaiiy i?aai?a iaeiai oaco ?iaeee
ca aeiiiiiaith i?eeaaeo “Aloka-SSD-650” (ssiii?y) ?c aeei?enoaiiyi
aeao/ee?a /anoioith 3,5 ? 5 Iaoe. Aeeiai?/io oie?eoeiiao??th i?iaiaeeee
c 7-ai ii 16 -e aeaiue iaino?oaeueiiai oeeeeo /a?ac aeaiue aai uiaeiy.
Ianoaaeaiiy ia o?iaai?oaeueio ?ioaeoe?th i?iaiaeeee c aeei?enoaiiyi
?ioiioa?iaioiiai aiae?co ? iace?a, iioa?aiaaieo ii iaoiaeo
?iiaiianueeiai-A?ice.
Aeey iiaiioe?iiiai aeyaeaiiy oa?aeoa?o iaoieia?? iaoeiaeo o?oa, ioe?iee
noaio y?/iee?a ? noiooiuei? a?iaeieia?/ii? iaoieia?? iaie canoiniaaia
eaia?ineii?y c o?iiinaeuei?iaineii??th ? a?iin??th y?/iee?a.
Eaia?ineii?th ?iaeee ca aeiiiiiaith onoaoeoaaiiy o??ie “Karl Storz”
(I?ia//eia ) a ia??iae ?c 8-ai ii 23-e aeaiue oeeeeo.
A aeeiai?oe? iaino?oaeueiiai oeeeeo ? a i?ioean? e?eoaaiiy i?iaiaeeee
aecia/aiiy ano?aae?ieo, i?iaanoa?iio, oanoinoa?iio, ethoa?i?coth/iai
(EA) oa oie?eoeinoeioethth/iai ai?iii?a (ONA), i?ieaeoeio a ne?iaaooe?
e?ia? ?ioiioa?iaioiei ? ?aae?i-?ioiieia?/iei iaoiaeii a?aeiia?aeii aei
?ino?oeoe?e iaai??a o??i – aeaioiaethaa/?a ( Hoffmann La Roche’,
Oaaoe?y); caaaeuei? O3, O4 (Immunotech,*ao?y). Aeine?aeaeaiiy
i?iaiaeeeeny a Oeaio?? eaai?aoi?ii? ae?aaiinoeee Aeiiaoeueeiai
iaaee/iiai oi?aa?neoaoo ? ?acoeueoaoe ii?aoeueiaoaaee c aeei?enoaiiyi
iaeaoo noaoenoe/ieo i?ia?ai IBM PC/AT.
Iaoe??ioee iniiaii? a?oie i?ney iia?aoe?? iaea?aeoaaee ?iooc?eio,
aioeaaeoa?eaeueio oa aiaeaacoth/o oa?ai?th. C ia?oi? aeiae i?ney
iia?aoe?? i?iaiaeeee oa?ai?th o?ce/ieie /eiieeaie: ia?ai?iiei iaai?oiei
iieai iecueei? /anoioe (“Iiethn-1”), iiiiiiey?ieie iecueei/anoioieie
?iioeuenaie i?yiieooii? oi?ie (“Aiaeioii-01A”) ? eieaeueiei iaaaoeaiei
oeneii (eaia?e ciiaeueii? aeaeiii?an?? ECAe “A?oa” (OO 785.000.000.0 ,
EII ?i A?oaia). I?ioeaaeo?e i?iaiaeeee uiaeiy, aei 15 ia eo?n, ii
i?ea?iaeueieo aaoi?nueeeo iaoiaeeeao.
Aeey ioe?iee aiaoiii-ooieoe?iiaeueiiai noaio iaoeiaeo o?oa i?ney
o??o?a?/ii? ei?aeoe?? ? a?aeiiaethth/iai e?eoaaiiy aeei?enoiaoaaee
e?iia?ao?/io ia?ooaaoe?th ( oi?aa?naeueiee eiiieaen AeEOA-01
(“Aen?ii”, i. ?aeaanuee ) ia 9-11 aeaiue iaino?oaeueiiai oeeeeo.
Ia?oee aoai ?aaa?e?oaoe?eii? oa?ai?? iieyaaa o i?ecia/aii? aioea?ioee?a
oe?ieiai niaeo?o, ui aieeaathoue ia OA?, noai?aii? ooo/iiai
a?ae?iia??oiiaoio ?ic/eiaie aeaeno?ai?a (iie?aethe?i) ?c aeiaeaaaiiyi
aetheiei?oeei?ae?a (a?ae?iei?oecii). C e?ioey 1-? aeiae i?ney iia?aoe??
i?ecia/aee iaai?oioa?ai?th 7-10 naain?a, c 5-? aeiae i?ecia/aee eaia?e
eieaeueiiai iaaaoeaiiai oeneo o e?eueeino? 15-20 ia eo?n ?c ia?a?aith ia
aei? iaino?oaoe??, a oaeiae ?c 3-5 aeiae noeioeyoe?th iaoeiaeo o?oa
aia?aoii “Aiaeioii-01-A” – 5-7 uiaeaiieo naain?a.
Ae?oaee aoai ?aaa?e?oaoe?? yaeya niaith ei?aeoe?th ia?aiai
-ai?iiiaeueieo ii?ooaiue ? a?ae??ciyany no?iai aeeoa?aioe?eiaaiei
i?aeoiaeii o caeaaeiino? a?ae iayaiino? noiooi?o ai?iiiaeueieo
ii?ooaiue. Oai?ei ?c NIEss ? ni?aa?aeiioaiiyi EA/ONA >3 a?aei?iyee
eiio?aoeaioe?th, ?aeiiaiaeoaaee aei?? aacaeueii? oaiia?aoo?e,
naiiniinoa?aaeaiiy ca iayai?noth ie?aeiiai oeeeiaiai neeco.
AE?ieai ?c NIEss ? niaeeiaei i?ioeanii, ?c ni?aa?aeiioaiiyi EA/ONA
3 oa ia?
i?noea ie?aiiaii?ay ?c ca?eueoaiiyi ?ici???a y?/iee?a. O ?ioeo
aeiaaeeao ie iaiaaeoaaeeny i?iaaaeaiiyi a?iin??. Oaeei /eiii, aeey
aecia/aiiy ianyao o??o?a?/iiai ao?o/aiiy ia y?/ieeao ?noioio ?ieue ia?
iiia?aaei? ai?iiiaeueia aeine?aeaeaiiy. Ie c’ynoaaee, ui y?/ieee, ye?
ciai? aeaeyaeathoue ye iie?e?noici?, iani?aaae? ? iciaeith ye i?i?ioi
o?ueio caoai?thaaiue: oeiiaiai NIEss, aoi?eiiiai NIEss aiane?aeie
caiaeueiiai i?ioeano ? ia??iioi?eoo oa a?iiooieoe?? y?/iee?a,
iaoiiaeaiith iaoieia??th ?ioeo aiaeie?eiieo i?aai?a. Ni?anoaaeaiiy
aeaieo ai?iiiaeueiiai aeine?aeaeaiiy e iniaeeainoae eaia?ineii?/ii?
ea?oeie ? a?noieia?/iiai aeine?aeaeaiiy aeicaieeee aeeoa?aioe?thaaoe, /e
? iaa??aeueiee /eiiee iniiaiei aai noiooi?i o aeieeiaii? aacie?aeiino?
a eiaeiiio eiie?aoiiio aeiaaeeo.
Iaie anoaiiaeaii, ui o oai?eo ?c ia?aeiiith aacie?aei?noth a 2-3 ?ace
/ano?oa aeyaeyany o?iic o?ia??aeueiiai a?aeae?eo iaoeiaeo o?oa ?
iie?e?noici? ci?ie y?/iee?a. O oai?eo ?c aoi?eiiith aacie?aei?noth
niinoa??aaeany aneiao??y ii?aaeaiiy aeenoaeueiiai a?aeae?eo iaoeiaeo
o?oa: ia?ao?iic iaeaea a 2 ?ace aeyaeyany /ano?oa e?ai?o/, i?ae
i?aai?o/. U?euei? aaaaoi?yaei? aeiaeieio?oai? niaeee iaeiaeiai /anoi
niinoa??aaeeny i?e ia?aeii?e ? i?e aoi?eii?e aacie?aeiino?. Ceoeiaee
i?ioean iaaeiei y?/iee?a iaa /?oeo neiao?e/i?noue, i?e/iio ?eoe? niaeee
iaaeiei y?/iee?a niinoa??aaeeny iaeaea a 2 ?ace /ano?oa o oai?eo ?c
ia?aeiiith aacie?aei?noth, a u?euei? aeiaeieiy?/ieeia? c?iuaiiy – o
oai?eo ?c aoi?eiiith aacie?aei?noth.
“Iae?” oi?ie aiaeiiao??ico aeyaeyeeny a 13,3%, 15,2% oa 18,2% a
a?aeiia?aeieo a?oiao; a iniiaiiio aeyaeyany aiaeiiao??ic e?eaeiai
-iaoeiaeo ca’ycie (c oaeith /anoioith), i?oo?iai-iaoeiai? neeaaeee
(6,7-8,7-9,1%), aiaeiiao??ic caaeiueiai eenoea oe?iei? ca’ycee iaoee ?
iaoeiai-eeoeiaiai iiaeeaeaiiy (3,3-5,3-4,5%). Aiaeiiao??ic na?icii?
iaieiiee iaoee aeyaeaiee o 2,17% iaoe??ioie 1-? i?aea?. ? a 2,27% o 2-?
i?aea?.; y?/iee?a -a 2,27% o 2-e i?aea?., aiaeiiao??ic iaoeiaeo o?oa
aeyaeaiee o 5,34% iaoe??ioie 1-? i?aea?. ? 2,27%-2-? i?aea?. Ii
i?aeia?iaei?e aia?eeainuee?e eeaneo?eaoe?? aiaeiiao??ico a on?o
aeiaaeeao a?aecia/aeany 1-a nooi?iue iioe?aiino? aiaeiiao??ico.
Iai?io?aei?noue iaoeiaeo o?oa niinoa??aaeany a 20% in?a eiio?ieueii?
a?oie, a 26,1% oai?eo 1-? i?aea?. ? a 31,8% 2-? i?aea?., /anoeiaa
i?iieeiaiiy eiio?anoo aeyaeaia a?aeiia?aeii o 60%, 52,17% ? a 56,8%
aeiaaee?a., a 20%, 19,9 % ? 11,4 % c’yniaaii i?ieneiaeueii -o?oaio
iai?io?aei?noue. Oaeei /eiii, o oai?eo ?c ii?aeiaiith aacie?aei?noth
ia?aaaaeiith oa?aeoa?enoeeith ? /anoeiaa i?io?aei?noue iaoeiaeo o?oa ?c
ii?ooaiiyi aca?ii?icoaooaaiiy inoaii?o a?aeiinii y?/iee?a.
A?aeiia?aeii aei eeaneo?eaoe?? J. Hulka (1978), a eiio?ieuei?e a?oi? 1-a
nooi?iue ceoeiaiai i?ioeano niinoa??aaeany a 60%, II -a nooi?iue -o
26,7%, III- y nooi?iue -o 13,3% oai?eo. O ae?iie 1-? i?aea?. 1-a
nooi?iue ceoeiaiai i?ioeano niinoa??aaeany a 61,0%, II -a nooi?iue -o
28,2%, III- y nooi?iue -o 10,8%. O oai?eo 2-? i?aea?. a?aeiia?aeii: 1-a
no. -o 56,9%, II- a no. – o 31,8%, III- y no. – o 11,3%. *aoaa?oee
nooi?iue ceoeiaiai i?ioeano ia aeyaeyany a aeiaei?e a?oi?. Iaie
aeyaeaiee a?eueoee a?aenioie ceoeiaiai i?ioeano 1-no. o oai?eo c
ii?aeiaiith aacie?aei?noth, i?ae i?e oeiia?e o?oaii-ia??oiiaaeuei?e
aacie?aeiino? (56% ca aeaieie Aania?iaa A.N. (1997), ui aeieaco? aaeeeo
?ieue iacia/ii ae?aaeaiiai ia??oiiaaeueiiai /eiieea o oi?ioaaii?
ii?aeiaii? aacie?aeiino?. Ca iaoeie niinoa?aaeaiiyie, o oai?eo /ano?oa
niinoa??aa?oueny 1-II nooi?iue ceoeiaiai i?ioeano a ii??aiyii? c oaeei
i?e o?oaii-ia??oiiaaeueiiio aacie?aeae? (ca aeaieie E.?. ?aaithoe
(1995)-III-1V no. ceoeiaiai i?ioeano niinoa??aa?oueny a 49,3% oai?eo).
A?ia?ieac?y aiaeiiao??th aeyaeyeany a 23 (48%) iaoe??ioie ?c
a?noieia?/ii i?aeoaa?aeaeaiei NIEss, ui aeieaco? aaoa?iaai?noue oeueiai
neiae?iio ? ciooo? a?eueo aeaaaeaii noaaeoeny aei a?iin?? aiaeiiao??th a
oeueiai eiioeiaaioo oai?eo, c iaeyaeo ia ?ieue caiaeueiiai i?ioeano ?
iiaeeea?noue yo?iaaieo oneeaaeiaiue. O 26 iaoe??ioie iniiaii? a?oie
aiaeiiao??e a?aeiia?aeaa oac? iaino?oaeueiiai oeeeeo; oea niinoa??aaeiny
a oai?eo ?c iacia/ii ae?aaeaiei niaeeiaei i?ioeanii iaaeiei iaoeiaeo
o?oa, ?aaoey?iei /?oeei iaino?oaeueiei oeeeeii ? ni?aa?aeiioaiiyi
EA/ONA= 1.5 ? i?e iaeeo oi?iao aiaeiiao??ico.
O eiio?ieuei?e a?oi? oai?eo aeyaeyeeny oae? niieo/aiiy /eiiee?a
aacie?aeiino?: o 6 (20%)- naeoinaeuei?ien + ceoeiaee i?ioean ia oii?
aiiaoeyoi?iiai ?aaoey?iiai oeeeeo; o 5 (16,7%)- ceoeiaee i?ioean + NIEss
ia oii? a?iiethoa?iiaiai ?aaoey?iiai oeeeeo; o 15 (50%)- NIEss +
ceoeiaee i?ioean ia oii? aiiaoeyoi?ii? ie?aiiaii?a? e o 4 (13,3%)-
yiaeiiao??ic + ceoeiaee i?ioean ia oii? ?aaoey?iiai aeaioaciiai oeeeeo.
O iaoe??ioie 1-? i?aea?oie aeyaeeeny oae? niieo/aiiy /eiiee?a
aacie?aeiino?: 1) naeoinaeuei?ien + ceoeiaee i?ioean ia oii? ?aaoey?iiai
aiiaoeyoi?iiai oeeeeo -o 12 (26,1%) iaoe??ioie; 2) ceoeiaee i?ioean
iaaeiei o?oa ? y?/iee?a + aoi?eiiee NIEss ia oii? a?iiethoa?iiaiai
?aaoey?iiai oeeeeo – o 10 (21,7%) iaoe??ioie; 3) NIEss + ceoeiaee
i?ioean i?e aiiaoeyoi?i?e ie?aiiaii?a? – o 17 (40%) oai?eo; 4) iae?
oi?ie yiaeiiao??ico + ceoeiaee i?ioean + ooioe?iiaeuei? ci?ie iaoeiaeo
o?oa ia oii? iiaiioe?iiiai aeaioaciiai oeeeeo – o 7 (15,2%) oai?eo .O
iaoe??ioie 2-e i?aea?oie iniiai? niieo/aiiy ca no?oeoo?ith aoee o? ae:
1) naeoinaeuei?ien + ceoeiaee i?ioean ia oii? aiiaoeyoi?iiai ?aaoey?iiai
oeeeeo – o 13 (29,6%) oai?eo; 2) ceoeiaee i?ioean iaaeiei o?oa ?
y?/iee?a + aoi?eiiee NIEss ia oii? a?iiethoa?iiaiai ?aaoey?iiai oeeeeo
-o 8 (18,2% ) iaoe??ioie; 3) NIEss + ceoeiaee i?ioean i?e aiiaoeyoi?i?e
ie?aiiaii?a? -o 17 (38,6%) oai?eo; 4) iae? oi?ie yiaeiiao??ico +
ceoeiaee i?ioean + ooieoe?iiaeuei? ci?ie iaoeiaeo o?oa i?e aeaioaciiio
iiaiioe?iiiio oeeee? – o 6 (13,6%) iaoe??ioie. Oaeei /eiii, a aeiaeii?
iaoe??ioee eiio?ieueii? e iniiaii? a?oi ia aoei iiiioaeoi?ii?
aacie?aeiino?. O i?eaaaeaiiio ia?ae?eo niieo/aiue /eiiee?a aieiaiee
iacaaii ia?oei. Iao? aeai? ocaiaeaeothoueny c oaeeie, ui io?eiai? a
?iaio? A.E. Ea?iaoo, I.A. Caiyo?ia (1989), Ei?iaoeueei? A.A.(1998), aea
a?ae??ciythoueny ca no?oeoo?ith niieo/aiue.
Na?aaei? ??ai? oanoinoa?iio a eiio?ieuei?e, 1-e ? 2-e i?aea?.
a?aeiia?aeii 5,57±0,28; 4,53±0,44;5,27±0,68 iiieue /e a??ia?aeii
ia?aaeuoaaee iieaciee o caei?iaeo (?0,05), i?ioa
noaoenoe/ii a??ia?aeii aoa aeua, i?ae o caei?iaeo -326,72 ±46,74 ieII/ie
(? 0,05)
? neeaa 4,86±0,42 iiieue /e, a a 2-e i?aea?. cieceany cia/ii ? neeaa
3,28±0,34 iiieue /e (?0,05). ??aaiue
i?iaanoa?iio ia 21-e aeaiue oeeeeo ca?eueoeany a 2-e i?aea?oi? iaeaea a
2 ?ace; o oai?eo 1-e i?aea?. a?i neeaa 8,86±0,23 a a 2-e i?aea?.
-17,4±0,36 iiieue /e (?>0,05) ? iaaeeaea?oueny aei ??aiy ai?iiio o
caei?iaeo -16,4±0,46 iiieue /e, (?>0,05). Oaeei /eiii, aeaiaoaiia
oa?ai?y i?ecaaea aei ii?iae?caoe?? ??aiy i?iaanoa?iio a na?aaeei?
ethoa?iiai? oace oeeeeo.
??aaiue i?iaanoa?iio ? ano?aae?ieo ia 7-e aeaiue iaino?oaeueiiai oeeeeo
i?ney 1-ai aoaio ?aaa?e?oaoe?? ca?eueoeany, aea nooo?aeo ci?i ai?noo
i?iaanoa?iio a na?aaeeio ethoa?iiai? oace ? ano?aae?ieo ia 14-e aeaiue
oeeeeo ia a?aeaoeiny. Aea a iaoe??ioie, ui iaea?aeoaaee 2-o aoaiio
oa?ai?th ci?ie eiioeaio?aoe?? noa?i?ae?a ianooieee a?eueo cia/i?,
a??ia?aeii cieceany ??aaiue oanoinoa?iio ia 7-e aeaiue – ?c 5,27±0,68
iiieue /e aei ?aaa?e?oaoe?? aei 3,28±0. 34 iiieue /e i?ney oaei?,
cieceany ??aaiue ano?aae?ieo ia 21-e aeaiue – ?c 1,48±0,30 aei
?aaa?e?oaoe?? aei 0,52 ± 0,25 iiieue/e. Iieacieee ano?aae?ieo ia 14-e ?
21-e aei? iaino?oaeueiiai oeeeeo, i?iaanoa?iio ia 7-e ? 21-e aei?
iaino?oaeueiiai oeeeeo ? oanoinoa?iio ia 7-e aeaiue oeeeeo noaee
aeecueeeie aei oaeeo o caei?iaeo ae?iie. Oea aeieaco? ei?enoue
i?iaaaeaii? aeaiaoaiii? ?aaa?e?oaoe?? aeey iie?ioaiiy noa?i?aeiaaiaco a
y?/ieeao.
I?ney i?iaaaeaiiy ?aaa?e?oaoe?eii? oa?ai?? anoaiiaeaii nooo?aa cieaeaiiy
i?ieaeoeio ia 7-e aeaiue oeeeeo a oai?eo 2-e i?aea?oie. Oae, ??aaiue
i?ieaeoeio a 1-e i?aea?. i?ney ?aaa?e?oaoe?? neeaa 720,42±28,53 ieII/ie,
a a 2-e -520,36±54,42 ieII/ie (?0,05).
Ni?aa?aeiioaiiy EA/ONA o 1-e i?aea?. i?ney 1-ai aoaio ?aaa?e?oaoe??
cieceeiny c 2,64 aei 2,21; o 2-e i?aea?. cieaeaiiy ni?aa?aeiioaiiy
EA/ONA aoei a?eueo cia/ia – ?c 2,24 aei 1,34 ? iaaeeaeaeiny aei oaeiai a
a?oi? caei?iaeo (1,51).
Ca aeaieie aeeiai?/ii? e?iiia?ooaaoe?? /a?ac 3 oa 6 i?nyoe?a i?ney
iia?aoe?? iieacieee iaeneiaeueiiai oeneo a 1-e i?aea?. noaiiaeee
a?aeiia?aeii 158,16±6,09 oa 155,76±6,07 ii. ?o. no..,a a 2-e i?aea?.-
115,43±4,07 oa 95,76±6,12 ii. ?o.no.(? 2 o 70%
ae?iie, ui aeicaiey? aaaaeaoe aeyaeai? ci?ie ia?ea?aie ii?ooaiue
a?iio?ca?ii- y?/ieeiai? nenoaie i?e ii?aeiai?e aacie?aeiino?.
4.I?e ii?aeiai?e aacie?aeiino? ii?ooaiiy ioiieththoue ia??oa??ei? oa
oeaio?aeuei? eaiee ?ai?iaeoeoeaii? nenoaie ? iio?aaothoue aeaiaoaiii?
?aaa?e?oaoe??. Ia?oee aoai i?neyiia?aoe?eii? ?aaa?e?oaoe?? (EIO,
iaai?oioa?ai?y, noeioeyoe?y iaoeiaeo o?oa) iiceoeaii aieeaa? ia i?aaie-
i?oai?, aea ia caaacia/o? iiaiioe?iii? ?aaa?e?oaoe?? ii?ooaieo
a?iio?ca?ii- y?/ieeiaeo ca’yce?a.
5.Iine?aeiaia i?ecia/aiiy ae?oaiai aoaio ?aaa?e?oaoe?? c aeei?enoaiiyi
?ineeiieo iiio?ii?a oa ai?iiiaeueii? ei?aeoe?? i?ecaiaeeoue aei
oi?ioaaiiy iiaiioe?iiiai aeaioaciiai oeeeeo, a?aeiiaeaiith i?io?aeiino?
iaoeiaeo o?oa, ui ae?aaea?oueny a ii?iae?caoe?? iieaciee?a o?oaiiai,
iaeneiaeueiiai ? aaciaiai oeneo; ii?iae?caoe?? oie?eoeiaaiaco, onoiaiiyi
a?ia?aiae?iaai?? ? a?ia?i?ieaeoeiai??, cieaeaiiyi ni?aa?aeiioaiiy EA/ONA
aei 1,5, a??ia?aeiei i?aeaeuaiiyi ??aiy i?iaanoa?iio ia 21-e aeaiue
oeeeeo.
6. Aaeaeaaoia o??o?a?/ia ei?aeoe?y c aeei?enoaiiyi aeaiaoaiii?
?aaa?e?oaoe?? aeicaiey? i?aeaeueoe /anoioo ianoaiiy aaa?oiino? aei 56,8%
i?ioe 13,3% i?e eiina?aaoeaiiio e?eoaaii?.
I?aeoe/i? ?aeiiaiaeaoe??
1. Eiina?aaoeaia oa?ai?y iaie?aeiino? iiaeiia iaiaaeeoeny 6 i?nyoeyie,
ai a?aenooi?noue aoaeoo na?ae/eoue i?i iayai?noue aaoa?iaaieo
ae?oai?yaeieo /eiiee?a iaie?aeiino?.
2.A aaiac? ii?aeiiii? aacie?aeiino? i?ia?aeio ?ieue a?ae?a?a?
ia??oiiaaeueiee /eiiee, ae?aaiinoeea yeiai iiaeeeaa eeoa i?e
eaia?ineii??. Oea aeicaiey? aena?oeeoe iniiaiee oa noiooi? /eiieee ?
aea? ciiao iine?aeiaiiai ?o onoiaiiy.
3.I?ney onoiaiiy aiaoii?/ieo ci?i aioo??oi?o noaoaaeo i?aai?a
a?aeiiaeaiiy ie?aeiino? aaeueiothoue aaoa?iaaii? ooieoe?iiaeuei?
/eiieee: ooieoe?iiaeueia a?ia?i?ieaeoeiai?y, eaoaioia a?ia?aiae?iaai?y,
ii?ooaiiy ai?noo aiiaaeio?ii?i?a.
4. ?aaa?e?oaoe?y oai?eo c ii?aeiaiith iaie?aei?noth ia? i?iaiaeeoeny a 2
aoaie: ia?oee – aeey noai?aiiy o?c?ieia?/iiai ?aia?aoeaiiai i?ioeano
(EIO, iaai?oioa?ai?y, noeioeyoe?y iaoeiaeo o?oa) i?ney iia?aoe??.
5. Ae?oaee aoai ?aaa?e?oaoe?? iai?aaeaiee ia ei?aeoe?th ai?iiiaeueieo
ii?ooaiue (IE, a?iie?eioei, aeaenaiaoacii), iie?auaiiy e?iaiia?ao oa
iai?io ?a/iaei a OeIN c canoinoaaiiyi ?ineeiiiai i?aia?aoo oaiaeai.
6. Iine?aeiaia aeaioaoaiia ?aaa?e?oaoe?y, eiio?ieueiaaia aeeiai?/iith
e?iiia?ooaaoe??th, ai?iiiaeueieie aeine?aeaeaiiyie oa ooieoe?iiaeueieie
oanoaie i?aeaeuo? aoaeoeai?noue e?eoaaiiy c 13,3% i?e o?aaeeoe?ei?e
oaeoeoe? aei 56,7% i?e i?iiiiiaai?e.
Nienie iaoeiaeo ?ia?o, iioae?eiaaieo ca oaiith aeena?oaoe??
1. Acaeiinaycue ai?iiiaeueiuo ia?ooaiee e ii?oieiae/aneeo eciaiaiee
aioo?aiieo iieiauo i?aaiia o aieueiuo n ni/aoaiiui aeaineei aanieiaeeai
// A?niee i?iaeai a?ieia?? ? iaaeeoeeie. — 1998. — ?16.- N.71-76.
(Niaao.: *aeea A.E..).
2. Eaia?ineiiey a aeeaaiinoeea ni/aoaiiiai aeaineiai aanieiaeey //
A?niee i?iaeai a?ieia?? ? iaaeeoeeie. — 1998. ? 17.- N.78-83.( Niaao.:
*aeea A.E..).
3. ?aaaeeeoaoeeiiiay oa?aiey i?e ni/aoaiiii aeaineii aanieiaeee // A?oea
eeeie/aneie e yenia?eiaioaeueiie iaaeeoeeiu. – 1998.-O.7, ?1. – N.
10-15. (Niaao.: *aeea A.E..).
4. Aeeyiea ?oooiie ay?iaaiiie iaa?ocee ia aaiaoieiae/aneea e
aeioeie/aneea iieacaoaee e?iae aa?aiaiiuo aeaiuei // Iaaeeei-nioeeae.
i?iaeaiu naiuee. — 1998. O.3, ?1.—N.54-57.( Niaao.: Ai?iaeei A.Ae.,
A?ia/aiei A..A., Ai?iaeei A.A..)
5. Eeii?oai?acenoaioi?noue ye neiioii i?e ia??oiiaaeuei?e aacie?aeiino?
// Iaoa??aee ? iaoeiai-i?aeoe/ii? i?aeia?iaeii? eiioa?aioe?? “
?ai?iaeoeoeaia caei?ia’y n?i’?: i?iaeaie oa oeyoe ?o ae??oaiiy” . Ee?a,
1997.- N.53.
6. Aaaaoioaeoi?ia aacie?aei?noue o ae?iie : ae?aaiinoeea ? oaeoeea
e?eoaaiiy // Iaoa??aee ? iaoeiai-i?aeoe/ii? i?aeia?iaeii? eiioa?aioe?? “
?ai?iaeoeoeaia caei?ia’y n?i’?: i?iaeaie oa oeyoe ?o ae??oaiiy” . Ee?a,
1997.- N.53.
7. Aeaa oeie o?aaeaiiy iaoeiaeo o?oa i?e o?oai?e aacie?aeiino? //
Iaoa??aee ? iaoeiai-i?aeoe/ii? i?aeia?iaeii? eiioa?aioe?? “
?ai?iaeoeoeaia caei?ia’y n?i’?: i?iaeaie oa oeyoe ?o ae??oaiiy” . Ee?a,
1997.- N.54.
8. Acaeiinaycue ai?iiiaeueiuo ia?ooaiee e ii?oieiae/aneeo eciaiaiee
aioo?aiieo iieiauo i?aaiia o aieueiuo n ni/aoaiiui aeaineei aanieiaeeai
// Iaaeaeoia?iaeiue eiia?ann “ Aeooaeueiua aii?inu eioaeoieiaee a
aeooa?noaa e aeiaeieiaee.”. Aeiiaoee .- 1998.- O.1 -N.57-58.
9. ?aaa?e?oaoe?eia oa?ai?y i?e niieooe? oaeoi??a iaie?aeiino? o ae?iie
// Iaaeaeoia?iaeiue eiia?ann “ Aeooaeueiua aii?inu eioaeoieiaee a
aeooa?noaa e aeiaeieiaee.” Aeiiaoee. – 1998.- O.1 -N.58-59.
Aiioaoe?y. N.N. O?ieia. Ae?aaiinoeea, e?eoaaiiy ? ?aaa?e?oaoe?y i?e
ii?aeiai?e ae?ii/?e aacie?aeiino?.
Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe
ca oaoii 14.01.01 – aeooa?noai ? a?iaeieia?y. ?inoeooo iaae?ao???,
aeooa?noaa ? a?iaeieia?? AII Oe?a?ie. Ee?a, 1998. ?oeiien.
?iaioa i?enay/aia canoinoaaiith ii?oi-ooieoe?iiaeueiiai iaoiaeo a
ae?aaiinoeoe? ii?aeiaii? ae?ii/i? iaie?aeiino? oa oi?ioaaiith
aiiiaaiieo a?oi oai?eo ca niieoeaie /eiiee?a. Aea/aii ii?oieia?/i?
iniaeeaino? aioo??oi?o noaoaaeo i?aai?a i?ae /an eaia?ineii?? oa a?iin??
y?/iee?a, ai?no noa?i?aeieo ? a?iio?ca?ieo ai?iii?a, aeai? oano?a
ooieoe?iiaeueii? ae?aaiinoeee i?e ??ciiiai?oieo niieo/aiiyo /eiiee?a.
Iieacaii aieiaio ?ieue ia??oiiaaeueiiai oaeoi?o a iaoiaaiac? ii?aeiaii?
aacie?aeiino? oa iine?aeiai?noue ?aaa?e?oaoe?eii? oa?ai??, ui aeo?ea? c
oeueiai. Aeyaeai? iaea?eueoa oa?aeoa?i? ai?iiiaeuei? ii?ooaiiy:
ooieoe?iiaeueia a?ia?i?ieaeoeiai?y, eaoaioia a?ia?aiae?iaai?y,
iao?c?ieia?/i? ni?aa?aeiioaiiy EA/ONA. Aecia/aii e?eoa??? ianyao
ao?o/aiiy ia y?/ieeao i?e ieanoe/ieo iia?aoe?yo. ?ic?iaeaii ? iaoeiai
iaa?oioiaaii 2-o aoaiio ?aaa?e?oaoe?th, ui caaacia/o? o?c?ieia?/i?
?aia?aoeai? i?ioeane ? ei?aeoe?th iae?i- ai?iiiaeueieo ii?ooaiue ?c
aeei?enoaiiyi ?ineeiieo iiio?ii?a.
Eeth/ia? neiaa: aacie?aei?noue ae?ii/a, niaeee, eaia?ineii?y, ai?iiie,
a?ia?i?ieaeoeiai?y, a?ia?aiae?iaai?y, ?aaa?e?oaoe?y, oaiaeai.
Aiiioaoeey. N.N. O?ieia. Aeeaaiinoeea, ea/aiea e ?aaaeeeoaoeey i?e
ni/aoaiiii aeaineii aanieiaeee.
Aeenna?oaoeey ia nieneaiea o/aiie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe
ii niaoeeaeueiinoe 14.01.01 – aeooa?noai e aeiaeieiaey. Einoeooo
iaaeeao?ee, aeooa?noaa e aeiaeieiaee AII Oe?aeiu. Eeaa, 1998. ?oeiienue.
?aaioa iinayuaia i?eiaiaieth ii?oi-ooieoeeiiaeueiiai iaoiaea a
aeeaaiinoeea, oi?ie?iaaieth aiiiaaiiuo a?oii aieueiuo i?e ni/aoaiiii
aeaineii aanieiaeee.
Ianeaaeiaaii 120 iaoeeaioie a aic?anoa io 19 aei 38 eao. 30 aeaiuei
iinea aeeaaiinoe/aneie eaia?ineiiee iieo/eee o?aaeeoeeiiioth
eiina?aaoeaioth oa?aieth e auee eiio?ieai; 90 iaoeeaioeai iniiaiie
a?oiiu i?iaaaeaia iia?aoeaiay eaia?ineiiey, a aeaeueiaeoai 46 ec ieo
iieo/eee ia?aue yoai ?aaaeeeoaoeee (1-y iiaea?.), a 44 iieo/eee
aeaooyoaiioth ?aaaeeeoaoeeth. Iiaea?oiiu iniiaiie a?oiiu auee
niiinoaaeiu ia oieueei ii aic?anoo, aeeeoaeueiinoe aanieiaeey, oa?aeoa?o
iaino?oaeueiiai oeeeea, ii e ii ii?oieiae/aneei eciaiaieyi iaoi/iuo
o?oa, ?acoeueoaoia ai?iiiaeueiuo enneaaeiaaiee e?iae e ooieoeeiiaeueiuo
oanoia.
Ia?aue yoai ?aaaeeeoaoeee caeeth/aeny a iacia/aiee n ia?auo nooie iinea
iia?aoeee ia?aiaiiiai iaaieoiiai iiey ieceie /anoiou (“Iiethn-1”),
iiiiiiey?iuo iecei/anoioiuo eiioeuenia i?yiioaieueiie oi?iu
(“Yiaeioii-01A”), eieaeueiiai io?eoeaoaeueiiai aeaaeaiey (ECAe “Aeoa”
(OO 785.000.000.0, EII ei. A?oaia).
Aoi?ie yoai ?aaaeeeoaoeee i?aaenoaaeye niaie ei??aeoeeth
iae?i-aoii?aeueiuo ia?ooaiee. Aieueiui n NIEss e niioiioaieai EA/ONA>3
ioiaiyee eiio?aoeaioeeth, ?aeiiaiaeiaaee ecia?aiea aacaeueiie
oaiia?aoo?u. Aieueiui n NIEss e niaa/iui i?ioeannii a oa?aieth aeeth/aee
iii-iaeii ia 3 oeeeea e oaiaeai. Aieueiui n niioonoaothuae
aeia?i?ieaeoeiaieae iacia/aee ai?ie?eioei ii 1/2 oaa. a oa/aiea o?ao
ianyoeaa. Iaoeeaioai n iaeuie oi?iaie yiaeiiao?eica iacia/aee i?aaiao?ee
(10 ia/noo) eee aeaiiaae (400 ia/noo) n iyouo nooie iinea iia?aoeee a
iai?a?uaiii ?aaeeia – 6 ianyoeaa.
Eco/aiu ii?oieiae/aneea iniaaiiinoe aioo?aiieo aaieoaeee i?e
eaia?ineiiee e aeiinee ye/ieeia, niaea?aeaiea noa?ieaeiuo e aeiioeca?iuo
ai?iiiia, aeaiiua oanoia ooieoeeiiaeueiie aeeaaiinoeee i?e ?acee/iuo
ni/aoaieyo oaeoi?ia aanieiaeey. Iieacaia aaaeouay ?ieue ia?eoiiaaeueiiai
oaeoi?a a iaoiaaiaca ni/aoaiiiai aanieiaeey e auoaeathuay ec yoiai
iineaaeiaaoaeueiinoue ?aaaeeeoaoeeiiiie oa?aiee. Auyaeaiu iaeaieaa
/anoua ai?iiiaeueiua ia?ooaiey: ooieoeeiiaeueiay aeia?i?ieaeoeiaiey,
eaoaioiay aeia?aiae?iaaiey, iaoeceieiae/iua niioiioaiey EA/ONA.
Ii?aaeaeaiu e?eoa?ee iauaia aiaoaoaeuenoa ia ye/ieeao i?e ieanoe/aneeo
iia?aoeeyo: i?e niioiioaiee EA/ONA aieueoa 3, iaee/ee ieeaiiaii?ae e
oaaee/aiiiai iauaia ye/ieeia iieacaia eeeiiaeaeiay ?acaeoeey iineaaeieo.
A inoaeueiuo neo/ayo iaiaoiaeeii ia?aie/eoueny aeiineae ye/ieeia.
?ac?aaioaia e iao/ii iainiiaaia 2-o yoaiiay ?aaaeeeoaoeey,
iaania/eaathuay oeceieiae/iua ?aia?aoeaiua i?ioeannu e ei??aeoeeth
iae?i- ai?iiiaeueiuo ia?ooaiee n eniieueciaaieai ?anoeoaeueiuo iiio?iiia
(oaiaeai). I?eiaiaiea oaiaeaia, iaeaaeathuaai i?ioeaiioa/iuie naienoaaie
a ioiioaiee OeIN iieacaei cia/eoaeueioth yooaeoeaiinoue a nicaeaiee
aioeaiiaaeio?iiiiai yooaeoa i?aeueiuo eiio?aoeaioeaia.
Eeth/aaua neiaa: aanieiaeea aeaineia, niaeee, eaia?ineiiey, ai?iiiu,
aeia?i?ieaeoeiaiey, aeia?aiae?iaaiey, ?aaaeeeoaoeey, oaiaeai.
The summary. S.S. Frolov. Diagnostics, treatment and rehabilitation of
connected female infertility.
Ohis is for scientific degree of the candidate of medical sciences on a
speciality 14.01.01 – obstetrics and gynaecology. Institute of
Pediatries, Obstetrics and Gynaecology, Academy of Sciences of Ukraine.
Kiev, 1998. Manuscript.
The work is devoted to application of a morfofunctional approach in
diagnostics, shaping of homogeneous groups women with connected female
infertility. The morphological features of internal genitals by
laparoscopy and biopsy of ovaries, blood contents steroids and
hypophysies hormons, datas of the tests of functional diagnostics of
various combinations of the factors infertility are investigated. The
leading role of the peritoneal factor in pathogenesis connected
infertility and sequence, implying from it, rehabilitation therapy is
shown. Most often hormonal violations are revealed: functional
hyperprolactinemia, latent hyperandrogenemia, inphysyologycal ratio
LH/FSH. The criterions of volume of interferences on ovaries during
plastic operations are determined. Rehabilitation ensuring physyologycal
revild processes and a correction neurohormonal of violations with use
vegetative nootrops is developed and scientifically justified .
Key words: female infertility, adhesions, laparoscopy, hormons,
hyperprolactinemia, hyperandrogenemia, rehabilitation, tanacan.
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