Шляхи підвищення ефективності кріохірургічного лікування фонових захворювань шийки матки: Автореф. дис… канд. мед. наук / Н.М. Волошина, Харк. держ.

21

OA?E?ANUeEEE AeA?AEAAIEE IAAeE*IEE

OI?AA?NEOAO

AIEIOEIA IAAe?ss IEEIEA?AIA

OAeE: 618.146-085:615.832.9:615.272.4

OEssOE I?AeAEUAIIss AOAEOEAIINO?

E??IO??O?A?*IIAI E?EOAAIIss OIIIAEO

CAOAI?THAAIUe OEEEE IAOEE

14.01.01-aeooa?noai ? a?iaeieia?y

Aaoi?aoa?ao

aeena?oaoe?? ia caeiaoooy iaoeiaiai nooiaiy

eaiaeeaeaoa iaaee/ieo iaoe

OA?E?A – 1999

Aeena?oaoe??th ? ?oeiien.

?iaioa aeeiiaia ia eaoaae?? aeooa?noaa ? a?iaeieia?? a Caii??cueeiio
?inoeooo? oaeineiiaeaiiy e?ea??a IIC Oe?a?ie.

Iaoeiaee ea??aiee aeieoi? iaaee/ieo iaoe, aeioeaio,

Eooeaiei Iaoae?y Noaiai?aia,

Caii??cueeee ?inoeooo oaeineiiaeaiiy e?ea??a,

IIC Oe?a?ie,

caa?aeoaa/ eaoaae?e aeooa?noaa ? a?iaeieia??.

Io?oe?ei? iiiiaioe:

-aeieoi? iaaee/ieo iaoe, i?ioani? A?euaiei Ieueaa Aaeaioei?aia,
Oa?e?anueeee ?inoeooo oaeineiiaeaiiy e?ea??a IIC Oe?a?ie, caa?aeoaa/
eaoaae?e ia?eiaoieia?? oa a?iaeieia??;

-eaiaeeaeao iaaee/ieo iaoe A?eoeia Ieueaa Ieaen??aia, Oa?e?anueeee
aea?aeaaiee iaaee/iee oi?aa?neoao IIC Oe?a?ie, anenoaio eaoaae?e
aeooa?noaa ? a?iaeieia?? ?1.

I?ia?aeia onoaiiaa- Aei?i?iiao?ianueea aea?aeaaia iaaee/ia aeaaeai?y IIC
Oe?a?ie, eaoaae?a aeooa?noaa ? a?iaeieia??.

Caoeno a?aeaoaeaoueny » 22 » ea?oiy 1999?. i 14 aiaeei? ia
can?aeaii?

niaoe?ae?ciaaii? a/aii? ?aaee Ae.64.600.01 i?e Oa?e?anueeiio
aea?aeaaiiio iaaee/iiio oi?aa?neoao? (310022, i.Oa?e?a, i?ini.Eai?ia, 4,
aoae.?1)

C aeena?oaoe??th iiaeia iciaeiieoenue o a?ae?ioaoe? Oa?e?anueeiai
aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (310022 i.Oa?e?a, i?ini.Eai?ia,4)

Aaoi?aoa?ao ?ic?neaiee » 19 » aa?aciy 1999?.

A/aiee nae?aoa?

niaoe?ae?ciaaii? a/aii? ?aaee

eaiaeeaeao iaaee/ieo iaoe, aeioeaio
Oaiueei I.I.

Caaaeueia oa?aeoa?enoeea ?iaioe

Aeooaeuei?noue i?iaeaie. E?eoaaiiy caoai?thaaiue oeeee iaoee i?iaeiaaeo?
caeiaoe oeaio?aeueia i?noea a nenoai? i?io?eaeoe/ieo cania?a ai?ioueae c
?aeii oeeee iaoee (Aioiai ss.A.,1989; Eioaiaae/ A.A.,
Noiaiei A.A.,1994). O oai?eo c oiiiaeie caoai?thaaiiyie oeeee iaoee
i?aeaeuo?oueny /anoioa iaie?aeiino?, ia?aae/anieo iieia?a,
aioo??oiueioo?iaiiai ?io?eoaaiiy ieiaeo, oneeaaeiaiue a iieiaao oa a
i?neyiieiaiaiio ia??iae? (AEanoeiaa A.A. oa ?io.,1991,1997;
I?eyiianueeee I.E., Nai/oe A.ss.,1990). Aeey e?eoaaiiy iaiieieia?/ieo
caoai?thaaiue oeeee iaoee cai?iiiiiaai? ??ciiiai?oi? eiina?aaoeai? oa
iia?aoeai? iaoiaee e?eoaaiiy. A a?iaeieia?/i?e i?aeoeoe? iaiaaeaia
aeei?enoaiiy eiina?aaoeaieo iaoiae?a e?eoaaiiy /a?ac iecueeo
aoaeoeai?noue oa /eneaii? ?aoeeaeeae iaoieia?? (Iineaeaiei ss.Ae. oa
?io.,1997; I?eeaineay A.I.,1997). A oie aea /an, c?inoa? ?ioa?an aei
aea/aiiy aoaeoeaiino? iaiaaeeeaiaioicieo iaoiae?a e?eoaaiiy oiiiaeo
caoai?thaaiue oeeee iaoee (Caii?iaeai A.I. oa ?io.,1996). A inoaii? ?iee
aaeeea oaaaa i?eae?ey?oueny ?ic?iaoe? aeeoa?aioe?eiaaiiai e?eoaaiiy
aaciooeeiieo caoai?thaaiue oeeee iaoee (I?ici?ia A.N. oa ?io.,1997;
Ferris D.G.1994; Jansen et al.,1994).

Iaea?eueo ?iniianthaeaeaiei iaoiaeii e?eoaaiiy oiiiaeo caoai?thaaiue
oeeee iaoee ? e??iaeano?oeoe?y (A?euaiei A. ?., Naiaeiie?nueeee A.I. oa
?io., 1987,1995). Iaeiae, ne?ae i?aee?aneeoe, ui i?ioean caai?iiy
ina?aaeeo i?ney e??iaeano?oeoe?? caeaaeeoue a?ae aaaaoueio oaeoi??a:
noaiiaeua a?ioeaiico i?oae, iaoiaeeee o??o?a?/iiai ao?o/aiiy, a oaeiae
oeeoiii?oieia?/iiai oa ?ioiieia?/iiai noaio oeeee iaoee ia iiiaio
e?eoaaiiy (Nai/oe A.ss., oa ?io.,1993; Oeueyiiaa ?.E.,1994). I?ioeane
a?aeiiaeaiiy ii?iaeueii? no?oeoo?e oeeee iaoee i?ney e??iaeano?oeoe??
caeaaeaoue a?ae aieeao ??ciiiai?oieo oaeoi??a. I?e/eie ?aoeeaeea?a
oiiiaeo caoai?thaaiue oeeee iaoee caeeoathoueny iaaeinoaoiuei aea/aieie.
Ia ?ic?iaeai? e?eoa??? ii aeyaeaiith iaeaoaeoeai?oi? oace
iaino?oaeueiiai oeeeeo aeey i?iaaaeaiiy e??ie?eoaaiiy oa caa??aathoueny
noia?a/eea? i?aeoiaee aei i?iaaaeaiiy i?neyiia?aoe?eiiai ia??iaeo.
Iaaeinoaoiuei aea/aii ieoaiiy i?i i?noeaaa canoinoaaiiy ?aiicaaithth/eo
cania?a.

Noai?aiiy inoaii?i /anii iiaeo e?ea?nueeeo cania?a, ui iathoue
?aiicaaithth/o, aioeieneaeaioio oa i?ioecaiaeueio ae?th, iaaea?
iiaeeea?noue aeei?enoaiiy ?o o ee?i?/i?e i?aeoeoe? oeyoii ?ic?iaee
eiiieaenieo noai e?eoaaiiy. Iaeiei c oaeeo e?ea?nueeeo cania?a ?
a?o/eciyiee i?aia?ao o?io?eacie?i. Canoinoaaiiy ?i’?eoe?eieo ?ic/ei?a ?
oaaeaoie o?io?eacie?io o ea?ae?ieia??, aaiaoieia??, o??o?a?? oa
iooaeueiieia?? aeaei aenieiaoaeoeai? ?acoeueoaoe (Ae?iaiaic N.I.,1994;
Aece? A.Ae. oa ?io.,1997). A a?iaeieia?/i?e i?aeoeoe? o?io?eacie?i
?ai?oa ia aeei?enoiaoaaany.

Ona oea na?ae/eoue i?i aeooaeuei?noue i?iaaaeaiiy aeine?aeaeaiue c
aea/aiiy iaoiae?a eiiieaeniiai e?eoaaiiy oiiiaeo caoai?thaaiue oeeee
iaoee c canoinoaaiiyi ?aiicaaithth/eo, i?ioecaiaeueieo, aioeieneaeaioieo
i?aia?ao?a a oiio /ene? iiaiai i?ea?iaeueiiai i?aia?aoo — o?io?eacie?io,
ui aeicaieeoue iie?ioeoe ?acoeueoaoe e??io??o?a?/iiai e?eoaaiiy,
ciaioeoe e?euee?noue ?icaeoeo oneeaaeiaiue oa ?aoeeaeea?a.

Ca’ycie ?iaioe c iaoeiaeie i?ia?aiaie, ieaiaie, oaiaie.

Aeeiiaia ?iaioa ? o?aaiaioii ieaiiai? iaoeiai-aeine?aeii? ?iaioe
eaoaae?e aeooa?noaa oa a?iaeieia?? Caii??cueeiai ?inoeoooo
oaeineiiaeaiiy e?ea??a ? aea?ae?a?no?aoe?? 0197V014315.

Iaoa ? caaaeaiiy aeine?aeaeaiiy.

Iaoith ?iaioe aoei i?aeaeuaiiy aoaeoeaiino? e??io??o?a?/iiai e?eoaaiiy
oiiiaeo caoai?thaaiue oeeee iaoee oeyoii ?ic?iaee eiiieaeniiai iaoiaeo
e??ie?eoaaiiy c o?aooaaiiyi oeeoiii?oieia?/iiai noaio oeeee iaoee, oace
iaino?oaeueiiai oeeeeo, ii?ooaiue o nenoai? IIE/AINC oa aeei?enoaiiyi
?aiicaaithth/eo i?aia?ao?a.

A?aeiia?aeii aei oeueiai aoee iinoaaeai? ianooii? caaea/?:

1. Aea/eoe ee?i?ei-eieueiineii?/i? oa oeeoiii?oieia?/i? ci?ie ai?oae?th
oeeee iaoee o ae?iie c oiiiaeie caoai?thaaiiyie oeeee iaoee i?ney
iiiie??ie?eoaaiiy i?ae /an oie?eoe?iiai? oa ethoa?iiai? oac
iaino?oaeueiiai oeeeeo.

2. I?iaanoe aeine?aeaeaiiy iieaciee?a i?ioeano ia?ieneaeaoe?? oa
aea/eoe noai aioeieneaeaioii? nenoaie caoenoo o ne?iaaooe? e?ia? oa
oea?a?eaeueiiio neec? iaoe??ioie c oiiiaeie caoai?thaaiiyie oeeee iaoee
a i?ioean? eiiieaeniiai e?eoaaiiy.

3. I?iaanoe ii??aiyeuei? eieueiineii?/i? ? oeeoiii?oieia?/i?
aeine?aeaeaiiy aieeao iaoeeo?aoeeeo, iae?ieoiai? ie?? oa o?io?eacie?io
ia i?ioeane a?aeiiaeaiiy ai?oae?aeueiiai oa?o oeeee iaoee i?ney
e??iaeano?oeoe??.

4. ?ic?iaeoe iaoiaeeeo eiiieaeniiai e??ie?eoaaiiy oiiiaeo caoai?thaaiue
oeeee iaoee c aeei?enoaiiyi o?io?eacie?io ? aeaoe ioe?ieo aoaeoeaiino?
aeei?enoaiiy eiai ??cieo e?ea?nueeeo oi?i.

5. C’ynoaaoe /anoioo ?icaeoeo oneeaaeiaiue oa ?aoeeaeea?a oiiiaeo
caoai?thaaiue i?ney iiiie??iaeano?oeoe?? oa eiiieaeniiai e??ie?eoaaiiy.

Iaoeiaa iiaecia iaea?aeaieo ?acoeueoao?a.

Aea/ai? oeeoiii?oieia?/i? ci?ie na?aae aacaeueieo, i?ii?aeieo oa
iiaa?oiaaeo ee?oei oeeee iaoee i?ney e??iaeano?oeoe?? a ??cieo oacao
iaino?oaeueiiai oeeeeo. Io?eiaia iiaa ?ioi?iaoe?y i?i no?oeoo?io
ia?aaoaeiao ai?oae?th i?ney e??iaeano?oeoe?? a ??cieo oacao
iaino?oaeueiiai oeeeeo oa i?ae aieeaii iaaeeeaiaio?a ? aeiaaaeaia
aeioe?euei?noue i?iaaaeaiiy e??io??o?a?/iiai e?eoaaiiy a ?aii?e
oie?eoe?iia?e oac?, ui i?eaiaeeoue aei oaeaeoi? ii?iae?caoe?? i?ioean?a
aeic??aaiiy ai?oae?aeueieo ee?oei oeeee oa a?aeiiaeaiith ai?oae?aeueiiai
oa?o.

Aia?oa aea/ai? i?noeaa? (o oea?a?eaeueiiio neec?) i?ioeane ia?aeeniiai
ieeneaiiy e?i?ae?a (IIE) oa noai aioeieneaeaioii? nenoaie caoenoo (AINC)
o caei?iaeo ae?iie oa iaoe??ioie c oiiiaeie caoai?thaaiiyie oeeee iaoee
I?iaaaeaii ?o ii??aiyiiy c? noaiii caaaeueieo i?ioean?a IIE/AINC o
ne?iaaooe? e?ia?. C’yniaaii ca’ycie oiiiaeo caoai?thaaiue oeeee iaoee c
i?noeaaeie i?ioeanaie ia?ieneaeaoe?? a i?aai?ci?. Aea/aia aeeiai?ea
i?ioean?a IIE/AINC i?ney iiiie??ie?eoaaiiy oa eiiieaenii? oa?ai?? c
aeei?enoaiiyi aioeieneaeaioieo i?aia?ao?a.

?ic?iaeaii eiiieaeniee iaoiae e??ie?eoaaiiy oiiiaeo caoai?thaaiue oeeee
iaoee ?c canoinoaaiiyi ?aiicaaithth/eo i?aia?ao?a oa i?iaaaeaia
ii??aiyeueia ioe?iea ?o aoaeoeaiino?. Aeiaaaeaii, ui iaee?au?
?acoeueoaoe aoee io?eiai? i?e canoinoaaii? o?io?eacie?io, a iaea?eueo
iioeiaeueiith e?ea?nueeith oi?iith i?e e?eoaaii? iaoieia?/ieo i?ioean?a
ia oeeoe? iaoee ? noiiceoi???. ?acoeueoaoe aeine?aeaeaiue ia?aeiieeai
na?ae/aoue i?i aeioe?euei?noue aeei?enoaiiy eiiieaeniiai iaoiaeo
e?eoaaiiy, yeee aeicaiey? cieceoe e?euee?noue oneeaaeiaiue oa
?aoeeaeea?a oiiiaeo caoai?thaaiue.

Aia?oa ?ic?iaeaii oeeoieia?/iee ne?ei?ia-oano aeey i?iaiico oa ?aiiueiai
aeyaeaiiy ?aoeeaeea?a caoai?thaaiue, ui aea? ciiao aeeoa?aioe?eiaaii
i?aeoiaeeoe aei o?eaaeino? aeeniaina?iiai iaaeyaeo ca a?oiith ae?iie c
oiiiaeie caoai?thaaiiyie oeeee iaoee.

I?aeoe/ia cia/aiiy iaea?aeaieo ?acoeueoao?a.

Ia i?aenoaa? ee?i?ei-noaoenoe/ieo, eieueiineii?/ieo oa
oeeoiii?oieia?/ieo aeine?aeaeaiue aeiaaaeaii aeioe?euei?noue i?iaaaeaiiy
e??ie?eoaaiiy a ia?o?e oac? iaino?oaeueiiai oeeeeo. Cai?iiiiiaaii
eiiieaeniee iaoiae e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee, c
aeei?enoaiiyi iaoeeo?aoeeeo, iae?ieoiai? ie?? oa a?o/eciyiiai i?aia?aoo
o?io?eacie?io, ui aeicaieeei ciaioeoe e?euee?noue oneeaaeiaiue oa
?aoeeaeea?a oiiiaeo caoai?thaaiue oeeee iaoee. ?ic?iaeaia iiaa
e?ea?nueea oi?ia i?aia?aoo — noiiceoi??? c o?io?eacie?iii, ui ?
iaea?eueo iioeiaeueiei aa??aioii aeey e?eoaaiiy iaoieia?/ieo noai?a
oeeee iaoee oa i?oae.

Iaa?oiooaaii ? ?ic?iaeaii oeeoieia?/i? e?eoa??? aeae?eaiiy iaoe??ioie o
a?oie ?eceeo ca aeieeiaiiyi ?aoeeaeea?a caoai?thaaiue, ye? iio?aaothoue
a?eueo o?eaaeiai niinoa?aaeaiiy. ?ic?iaeai? iaoiaaiaoe/ii iaa?oioiaai?
i?aeoe/i? ?aeiiaiaeaoe?? c i?io?eaeoeee oneeaaeiaiue, ciaioaiith
?aoeeaeea?a oa aeeniaina?iiai iaaeyaeo ca iaoe??ioeaie c oiiiaeie
caoai?thaaiiyie oeeee iaoee. Cai?iiiiiaai? iia? iaoiaee ae?aaiinoeee ?
e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee aeei?enoiaothoueny a ?iaio?:
eaa?iao?a iaoieia?? oeeee iaoee oa IN* «Eiioia?», «Iioi? N?/»
i.Caii??aeaey; Ieoaee?anuee?e, I??o?anuee?e oa ?ic?anuee?e Oe?E
Caii??cueei? iaeano?, i.E?aiai/oe Iieoaanueei? iaeano?, ?aai?anuee?e
Oe?E Oa?niinueei? iaeano?. Iaoa??aee ?acoeueoao?a aeine?aeaeaiue
ai?iaaaeaeai? a iaaeaaia?/iee i?ioean ia eaoaae?ao aeooa?noaa oa
a?iaeieia?? Caii??cueeiai ?inoeoooo oaeineiiaeaiiy e?ea??a oa
Caii??cueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo.

Iniaenoee aianie caeiaoaa/a.

Aaoi? naiino?eii aeeiiaea ee?i?ei-eieueiineii?/i? oa oeeoieia?/i?
ianoaaeaiiy, a oaeiae a?aea o/anoue a i?iaaaeaii? oeeoiii?oieia?/ieo,
a?noieia?/ieo oa a?io?i?/ieo ianoaaeaiue o 393 ae?iie c iaoieia?/ieie
ci?iaie ia oeeoe? iaoee ? 30 caei?iaeo ae?iie, ca ia??iae c 1993 ii 1998
?iee. Naiino?eii i?iaaaeaii aeeniaina?iee iaaeyae ca oai?eie oa ?o
e?eoaaiiy. Iaa?oioiaaia iaoiaeeea eiiieaeniiai e??io??o?a?/iiai
e?eoaaiiy iaoe??ioie c oiiiaeie caoai?thaaiiyie oeeee iaoee.
Cai?iiiiiaaia iiaa e?ea?nueea oi?ia i?aia?aoo o?io?eacie?io–
noiiceoi???. ?ic?iaeaii e?eoa??? aecia/aiiy a?oi ?eceeo na?aae oai?eo
i?ney e??ie?eoaaiiy ii ?icaeoeo ?aoeeaeea?a caoai?thaaiiy. I?iaaaeaii
aiae?c, noaoenoe/io ia?iaeo io?eiaieo ?acoeueoao?a. A?io?i?/i? oa
oeeoiii?oieia?/i? aeine?aeaeaiiy aeeiiai? a ee?i?/i?e eaai?aoi??? C?OE ?
iaoieiaiaiaoii?/iiio a?aeae?e? IN* «Eiioia?».

Ai?iaaoe?y ?acoeueoao?a aeena?oaoe??.

?acoeueoaoe ?iaioe aoee i?aaenoaaeai? ia: O c’?cae? aeooa??a-a?iaeieia?a
Oe?a?ie (i.Iaeana,1996); iaoeia?e eiioa?aioe?? «Aeooaeuei? ieoaiiy
oai?aoe/ii? ? ee?i?/ii? iaaeeoeeie ia no/aniiio ??ai?» (i.
Iieoaaa,1996); 1-io Iaoe?iiaeueiiio eiia?an? Oe?a?ie c ?ioiieia??,
aea?aieia?? oa ?ioii?aaa?e?oaoe?? (i.Aeoooa,1998); i?aeia?iaei?e
iaoei-i?aeoe/i?e eiioa?aioe?? «Ii?oieia?y i?aeoe/i?e aaoa?eia??? oa
iaaeeoeei?» (i.A?ea Oea?eaa,1998); can?aeaiiyo anioe?aoe?? e?ea??a
aeooa??a-a?iaeieia?a Caii??cueei? iaeano? (1997-1998); can?aeaii?
eaoaae?e aeooa?noaa oa a?iaeieia?? ?1 Oa?e?anueeiai aea?aeaaiiai
iaaee/iiai oi?aa?neoaoo (1999). Ai?iaaoe?y ?iaioe i?iaaaeaia ia
ni?eueiiio can?aeaii? eaoaae? aeooa?noaa oa a?iaeieia??, i?aai?caoe??
ioi?iie caei?ia’y, eaoaae?e caaaeueii? ee?i?/ii? iaoieia?? Caii??cueeiai
?inoeoooo oaeineiiaeaiiy e?ea??a oa eaoaae?e aeooa?noaa oa a?iaeieia??
Caii??cueeiai aea?aeaaiiai iaaee/iiai oi?aa?neoaoo (1998).

Ioae?eaoe??.

Ca ?acoeueoaoaie aeena?oaoe?eiiai aeine?aeaeaiiy iioae?eiaaii 14
iaoeiaeo i?aoeue, c ieo 6 — o oaoiaeo aeaeaiiyo AAE Oe?a?ie; 5 — o
ca??eao iaoeiaeo noaoae; 3 — o ca??eao oac ? aeiiia?aeae eiioa?aioe?e.

Ianya ? no?oeoo?a aeena?oaoe??.

?iaioo aeeiiaii ia 180 noi??ieao iaoeiiieniiai oaenoo, ?ethno?iaaii 23
oaaeeoeyie oa 29 iaethieaie, ye? caeiathoue 28 noi??iie. Aeena?oaoe?y
neeaaea?oueny c? anooio, iaeyaeo e?oa?aoo?e, iieno iaoiae?a
aeine?aeaeaiiy, 4 ?icae?e?a aeanieo aeine?aeaeaiue, aiae?co e
ocaaaeueiaiiy ?acoeueoao?a aeine?aeaeaiiy, aeniiae?a, i?aeoe/ieo
?aeiiaiaeaoe?e, nieneo aeei?enoaieo aeaea?ae, c ieo 237 ee?eeeoeath ?
143 eaoeiith.

INIIAIEE CI?NO ?IAIOE

Iaoa??aee oa iaoiaee aeine?aeaeaiiy.

A iniiao ?iaioe iieeaaeaii iaoa??aee ianoaaeaiiy 393 ae?iie c oiiiaeie
caoai?thaaiiyie oeeee iaoee. Eiio?ieueio (ia?oo) a?oio neeaee 30
caei?iaeo ae?iie. An? ianoaaeai? ae?iee c oiiiaeie caoai?thaaiiyie oeeee
iaoee aoee ?iciiae?eai? ia o?noue a?oi. Iaoe??ioie 2-? – 5-? a?oi, a
caeaaeiino? a?ae oace iaino?oaeueiiai oeeeeo ? i?iaaaeaiiy
e??ie?eoaaiiy, ?iciiae?eyee ia i?aea?oio A (e??ie?eoaaiiy canoiniaaii a
ethoa?iia?e oac?) oa i?aea?oio A (e??ie?eoaaiiy i?iaaaeaii a
oie?eoe?iia?e oac?). Aeey aea/aiiy aieeao i?ioecaiaeueieo oa
aioeieneaeaioieo i?aia?ao?a ia i?ioeane ?aia?aoe?? i?ney
e??iaeano?oeoe??: 30 ae?iie (3-y a?oia) io?eioaaee iaoeeo?aoeee o
noiiceoi??yo; 28 ae?iie (4-oa a?oia) io?eioaaee noiiceoi??? c
iae?ieoiaith ie??th; 110 ae?ieai (5-oa a?oia) aoa i?ecia/aiee iiaee
a?o/eciyiee i?aia?ao o?io?eacie?i o noiiceoi??yo ia i?ioyc? 10 ae?a
i?ney e??iaeano?oeoe??.

Aeey ii??aiyeueiiai aea/aiiy aoaeoeaiino? ??cieo e?ea?nueeeo oi?i
o?io?eacie?io i?e eiiieaeniiio e?eoaaii? oiiiaeo caoai?thaaiue
iaoe??ioeai 6-? a?oie (30 ae?iie) i?ecia/aee oaaeaoee o?io?eacie?io (ii
iaei?e oaaeaooe? (0,1a) o?e/? ia aeaiue) oa iaoe??ioeai 7-? a?oie (30
ae?iie) canoiniaoaaee 2,5 % ?ic/ei o?io?eacie?io o aeaeyae? aie?eaoe?e
ia oaiiii?- i?noeaai, i?ioyaii 10 aei?a i?ney e??iaeano?oeoe??.

A?oie aoee ?aiaeii?ciaai? ca a?eii, ee?i?/iith oa?aeoa?enoeeith,
aeaai?noth caoai?thaaiiy. Oiiia? i?ioeane ia oeeoe? iaoee
ae?aaiinooaaeeny ca aeiiiiiaith eieueiineii?/iiai ianoaaeaiiy,
oeeoieia?/iiai oa ii?oieia?/iiai aeine?aeaeaiiy.

?icoe?aia eieueiineii?/ia ianoaaeaiiy i?iaiaeeeinue ca aeiiiiiaith
eieueiineiio EN-1. Aeey ioe?iee noaio oeeee iaoee aeei?enoiaoaaee
ii?oieia?/io eeaneo?eaoe?th ?.A.sseiae?ai? ? A.A.Eoeooa (1977) oa
ee?i?ei- aiaeineii?/io eeaneo?eaoe?th ?.A.Eioaiaae/ ? E.I.Aai?ii?
(1997). Eieueiineii?/i? oa oeeoieia?/i? aeine?aeaeaiiy i?iaiaeeeeny
aei-, a oaeiae i?ney e??ie?eoaaiiy ia 7-io — 14-oo -28-io aeiao oa /a?ac
6 — 8 — 12 oeaei?a. A?aeaeaeai? ?acoeueoaoe aea/aeeny /a?ac 6 — 12 — 18
oa 24 i?nyoe?. Iacee c iiaa?oi? oeeee iaoee oa aiaeioea?a?eno
oa?aoaaeeny ca ?iiaiianueeei – Aeica oa ii A?aio. Ioe?iea nooiaith
/enoioe i?oae i?iaiaeeeanue ca caaaeueiii?eeiyoith iaoiaeeeith, a
oeeoieia?/i? aeine?aeaeaiiy — c o?aooaaiiyi aeaieo I.A.A?naiue?ai?
(1977).

E??iaeano?oeoe?th i?iaiaeeee e??iaaiiei aia?aoii EAA-01, Iaeanueeiai
?inoeoooo oieiaeeeueii? i?iieneiaino?. Oaeaeeei ioieiaeaeaiiyi (aei
-196N) ? iia?eueiei a?ae?a??aaiiyi aeinyaaany iaeneiaeueiee aoaeo
e??iaeano?oeoe?? o?aaeaii? ae?eyiee. O?eaae?noue iaei??? i?ioeaaeo?e 4-5
oaeeei. Aeey e?eoaaiiy aeoii?e oa

cii o?ainoi?iaoe?? canoiniaoaaee iaeii?aciaa ?o caii?iaeoaaiiy, c
?icoe?aiiyi o?iioo eueiaeo ia 2-4 ii ca iaae? ina?aaeeo iaoieia?/ii
ci?iaieo oeaiei. I?e e?eoaaii? aiaeiiao??ico, iinoeiaaoeyoe?eiiai
oea?a?eico oa eaeeiieae?? oeeee iaoee aeei?enoiaoaaee aeaioieoo?aa
caii?iaeoaaiiy, ye ?aeiiaiaeiaaii a ?iaioao (A?euaiei A.?. oa ?io.,1987;
Caii?iaeai A.I. oa ?io.,1996). Ino??aeia? o?aaeaiiy ai?oae?th oeeee
iaoee caii?iaeoaaee ae?eyieaie ?c canoinoaaiiyi aie?eaoi??a iaiao?aeii?
oi?ie. An? e??io??o?a?/i? iia?aoe?? i?iaiaeeee aiaoeaoi?ii aac
iiia?aaeiueiai iaacaiethaaiiy. I?aoeacaeaoi?noue oai?eo ia
ii?oooaaeanue. Iaoe??ioeai eiaeii? a?oie iaaeaaaeenue ?aeiiaiaeaoe?? c
iiaeaeueoiai e?eoaaiiy.

Ii?oieia?/i? aeine?aeaeaiiy a?iin?e i?iaiaeeeenue a i?ioean?
aa?eo?eaoe?? ae?aaiico. A?noieia?/i? i?aia?aoe oa?aoaaee aaiaoieneeeiii
? aiceiii, ca Aanoii oa noaaeee O?E-?aaeoe?th. O ae?iie c oiiiaeie
caoai?thaaiiyie oeeee iaoee aea/aee iieacieee a?eueii?aaeeeaeueiiai
ieeneaiiy e?i?ae?a o ne?iaaooe? e?ia? oa i?noeaai, o oea?a?eaeueiiio
neec? aei oa i?ney iiiie??ie?eoaaiiy, a oaeiae eiiieaeniiai
e??ie?eoaaiiy ?c canoinoaaiiyi aioeieneaeaio?a. Eiioeaio?aoe?th
ae??iiaeo eaoii?a (AeE), a?ae?iia?aeen?a e?i?ae?a (AIE/ie) aecia/aee ca
iaoiaeii A.A.Aaa?eeiaa (1988), oaeaee?noue ia?ieneaeaoe?? ca iaoiaeii
O.Iiiiaa oa E.Iaeeianueei? (1971). Aecia/aiiy ??aiy caaaeueieo e?i?ae?a
(CE) i?iaiaeeeiny c aeei?enoaiiyi iaai??a ?aaeoea?a o??ie Lachema
/*ao?y/. I?i noai aioeieneaeaioieo i?ioean?a ?iaeee aeniiaee ca
iieacieeaie eaoaeace (EO), yeo aecia/aee ca iaoiaeii I.A.Ei?iethe (1988)
oa a?oai?i?a A oa A, ye? aecia/aee ca iaoiaeii Thompson ? ni?aaao.(1973)
a iiaeeo?eaoe?? ?.*.*a?iyoneaia (1982).

Caaaeueiiee?i?/i? aiae?ce i?iaiaeeee on?i ae?ieai aei e??ie?eoaaiiy.
Naiaoe?y i?oae aoea ia?oei aoaiii o e?eoaaii? oiiiaeo caoai?thaaiue
oeeee iaoee. Io?eiai? e?euee?ni? ?acoeueoaoe aeine?aeaeaiue ia?iaeai? ca
aeiiiiiaith iaoiae?a aa??aoe?eii? noaoenoeee, aeeth/ath/e ei?aeyoe?eiee
aiae?c. Ii??aiyiiy a??ia?aeiino? a?aei?iiinoae cae?enithaaeinue ca
e?eoa???i No’thaeaioa. ??cieoeth aaaaeaee aeinoia??iith i?e ? 0,05.

?acoeueoaoe aeine?aeaeaiue oa ?o iaaiai?aiiy.

Aea/aiiy noaio oeeee iaoee aoei i?iaaaeaii a eaa?iao? “Iaoieia?? oeeee
iaoee” IN* «Eiioia?» i?ioyaii 1993-1998 ?ie?a. On? ae?iee
aaciina?aaeiuei ciaoiaeeeenue i?ae iaoei iaaeyaeii 1,5-2 ?iee.
Ia?aaaaeia e?euee?noue iaoe??ioie aoee o iaea?eueo ni?eyoeeaiio aeey
?ai?iaeoeoeaii? ooieoe?? a?oe?. Na?aaei?e a?e ae?iie: ia?oi? a?oie neeaa
34,22,1 ?iee; ae?oai? — 29,21,2; o?aouei? — 29,51,8; 4-? — 28,01,6; 5-?
— 27,61,1; 6-? — 26,21,2 oa 7-? — 27,8 1,4 ?iee. O ae?iie ianoaaeaieo
a?oi ia aeyaeaii nooo?ai? ??cieoe? o oa?aeoa?enoeoe? iaino?oaeueii?
ooieoe??.

C aiaiiaco c’yniaaii, ui o a?eueoino? ae?iie aoee iieiae oa aai?oe: o
80% — 1-? a?oie; o 82% — 2-? a?oie; 93,3% — 3-? a?oie; 78,6% — 4-?
a?oie; 75,5% — 5-? a?oie. O 6-e oa 7-e a?oiao oeae iieaciee ia
a?ae??ciyany a?ae iiia?aaei?o a?oi.

Nea?ae ia iaoieia?/i? aeae?eaiiy c i?oae aoee o a?eueoino? ianoaaeaieo
ae?iie (aei 57,2%). A?ia?nae?aoe?y c? noaoaaeo oeyo?a ? iae/ano?uith
nea?aith a?iaeieia?/ieo oai?eo c iaoieia??th oeeee iaoee.
Aaeoa??ineii?/ia aeine?aeaeaiiy aeae?eaiue i?oae i?aeoaa?aeeei
iayai?noue iaeaea o iieiaeie ae?iie on?o a?oi (ie??i ia?oi?) eieuei?o?a
??ciiai aaiaco. Oeei iaoe??ioeai aei ii/aoeo e??ie?eoaaiiy i?iaiaeeee
iaia’yceiaa ao?iiaoiaaiaoe/ia e?eoaaiiy, c iiaeaeueoei eiio?ieai
aeaeoaeaiiy. A?eue ia aoa iaoiaiiiii?/iei neiioiiii o ianoaaeaieo
ae?iie.

I?e eieueiineii?/iiio aeine?aeaeaii? o ianoaaeaieo ae?iie iae/ano?oa
niinoa??aaeeny aeoii?y oeee?iaee??/iiai ai?oae?th c iacae?i/aiith oa
cae?i/aiith ciiaie o?ainoi?iaoe??. Oae? eieueiineii?/i? ea?oeie
a?aecia/ai? o 61,8% iaoe??ioie ae?oai? a?oie, 66,7% — 3-?, 71,4% — 4-?,
59,0% — 5-?, 50,0%- 6-? oa 60,0% — 7-? a?oi. Aiaeiiao??ic oa
iinoeiaaoeyoe?eiee oea?a?eic aeyaeaii o 10% iaoe??ioie 6-? oa 7-? a?oi,
o 20,9% ae?iie 5-? a?oie, 17,8% — a 4-e ? 16,7% — a o?ao?e a?oiao. O
ae?oa?e a?oi? niinoa?aaeaiiy oeae iieaciee cono??/aany o 12,7%. I?inoa
eaeeiieae?y oeeee iaoee aac aoei?? ee?oei anoaiiaeaia a?ae 4,8% a
ae?oa?e a?oi? aei 10% a 7-e a?oi? ae?iie.

Ia /an caa?iaiiy aei e?ea?y o ae?iie 2-? — 7-? a?oi o?eaae?noue oiiiaeo
caoai?thaaiue noaiiaeea a?ae oanoe i?nyoe?a aei i’yoe ?ie?a. Na?aaei?
iieacieee o?eaaeino? caoai?thaaiiy noaoenoe/ii ia a?ae??ciyeenue o
a?oiao niinoa?aaeaiiy ? noaiiaeee 1,8-2,8 ?iee. A?eueo?noue ianoaaeaieo
ae?iie io?eioaaee iiia?aaei? eiina?aaoeaia oa ae?aoa?iio??o?a?/ia
e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee a ??cieo iaaee/ieo
caeeaaeao.

Ee?i?ei-eaai?aoi?ieie aeine?aeaeaiiyie o eiio?ieuei?e a?oi? anoaiiaeaii
ianooii? iieacieee iaoaaie?o?a IIE oa AINC o oea?a?eaeueiiio neec?:
AIE/ie — 0,540,06 o.i.; AIE/ia — 1,330,16 o.i.; AeE-0,240,05 o.i.;
CE-0,480,03 a/e. ??aaiue eaoaeace a oea?a?eaeueiiio neec? caei?iaeo
ae?iie noaiiaea 42,12,0 ieao/ /an/ e;, a?oai?io A — 2,20,3 ieiieue/ e;,
a?oai?io A — 6,20,7 ieiieue/ e. O ae?iie c iaoieia??th oeeee iaoee aei
e??io??o?a?/iiai e?eoaaiiy i?noeaa? iieacieee i?ioean?a IIE/ AINC cia/ii
a?ae??ciyeenue a?ae iieaciee?a a?oie caei?iaeo ae?iie. O ieo iathoue
i?noea i?aeaeuai? ??ai?: a?ae?iia?aeen?a a 1,7 ?aca, ae??iiaeo eaoii?a a
aeaa ?ace, oaeaee?noue ia?ieneaeaoe?? a 1,2 ?aca oa caaaeueieo e?i?ae?a
a 1,9 ?aca (?0,05). C?inoaiiy ??aiy i?iaeoeo?a IIE a oea?a?eaeueiiio
neec? ? iaeiei ?c oaeoi??a, ye? iaoiiaeththoue ?icaeoie i?noeaaeo
iaoieia?/ieo ci?i. A nenoai? aioeieneaeaioiiai caoenoo a?aecia/aii
aeenaaeain ooieoe?iiaeueii? aeoeaiino? ?? eaiie. Aeyaeaii i?aeaeuaiiy
??aiy eaoaeace a 1,2 ?aca. A?aecia/aii cieaeaiiy eiioeaio?aoe?? ?aoeiieo
a aeaa ?ace, oieioa?ieo a 1,6 ?aca (?0,05), ui ni?aiaaea? c
e?oa?aoo?ieie aeaieie, ye? na?ae/aoue, ui i?io?eaiiy iaoieia?/ieo
i?ioean?a a?aeaoaa?oueny ia oii? aeao?oeeoo a?oai?iii? caaacia/aiiino?
(Aeooaeei A.A., 1986; Eoeaeia A.?. oa ?io.,1994; Wolf G.,1984).

I?e eieueiineii?/iiio niinoa?aaeaii? oa aea/aii? iniaeeainoae
?aia-?aoeaieo i?ioean?a ai?oae?th oeeee iaoee i?ney e??iaeano?oeoe??,
yea i?iaiaeeeany a ??cieo oacao iaino?oaeueiiai oeeeeo, anoaiiaeaia
??cia aeeiai?ea oa?i?i?a a?aeoi?aiaiiy no?oio. A i?aea?oi? A, aea ae?iee
io?eioaaee e?eoaaiiy i?ae /an ethoa?iiai? oace, i/euaiiy iaoieia?/iiai
ina?aaeeo a?ae no?oio a?aeaoeiny ia ae?oaiio oeaei? o 26,1 % oai?eo. Ia
oeae /an o i?aea?oi? A, aea ae?iee io?eiaee e?eoaaiiy o oie?eoe?iia?e
oac?, a?aeoi?aiaiiy no?oio a?aeaoeiny o 79,4% iaoe??ioie. Na?aaei?
oa?i?ie i/euaiiy oeeee iaoee a?ae no?oio noaiiaeee a i?aea?oi? A —
12,90,4 aeiae, a a i?aea?oi? A-16,20,4 aeiae (?0,05).

?icoe?aia eieueiineii?y aeyaeea yne?aa?oo aaneoey?ecaoe?th iiaa?oi?
oeeee iaoee ca ?aooiie ?icoe?aieo noaeei o ae?iie i?aea?oie A. ?aaeoe?y
ia ?ic/ei ioeoo aoea a?eueo ae?aaeaiith o iaoe??ioie i?aea?oie A. O
ae?iie, ye? i?ie?eiaai? o oie?eoe?iiao oaco iaino?oaeueiiai oeeeeo,
iaaaeee? ae?eyiee aaaaoioa?iaiai ai?oae?th c’yaeyeenue ii ia?eoa???
ina?aaeeo i?ney e??iaeano?oeoe?? ia ae?oaiio oeaei? niinoa?aaeaiiy, a a
i?aea?oi? A – ia 3-4-io oeaeiyo.

I?ioeane a?aeiiaeaiiy ai?oae?aeueiiai oa?o oeeee iaoee o ae?iie
i?aea?oie A oaeiae i?io?eaee nei??oa, i?ae a i?aea?oi? A. I?e
eieueiineii?/iiio eiio?ie? ia 5-6 oeaei? i?ney e??ie?eoaaiiy,
ai?oae?caoe?y iiaa?oi? oeeee iaoee a?aeaoeany o 50,7% ae?iie, ye? aoee
i?ie?eiaai? a ia?o?e oac? oeeeeo ? eeoa o 12,0% ae?iie, ye? io?eiaee
e?eoaaiiy o ae?oa?e oac? iaino?oaeueiiai oeeeeo. Ia 8-io oeaei?
niinoa?aaeaiiy i?e eieueiineii?? o 93,2% ae?iie i?aea?oie A oeeea iaoee
aoea ae?eoa oa?ii ieineiai ai?oae?th c iiceoeaiith i?iaith Oeea?a. A oie
aea /an, i?ioean ai?oae?caoe?? oeeee aoa caaa?oaiee eeoa o 79,3% ae?iie
i?aea?oie A. Na?aaei? oa?i?ie ai?oae?caoe?? noaiiaeee a i?aea?oi?
A-7,60,2 oeaei?, a a i?aea?oi? A — 6,30,3 oeaei? (?0,05). Io?eiai?
ee?i?ei-eieueiineii?/i? ?acoeueoaoe i?i i?enei?aiiy ?aia?aoeaieo
i?ioean?a iiaa?oi? oeeee iaoee i?ney e??iaieeao o ia?o?e oac?
iaino?oaeueiiai oeeeeo i?aeoaa?aeaeaii iiaeeaeaieie oeeoieia?/ieie
aeine?aeaeaiiyie aeeiai?ee aeeoa?aioe?eiaee aaaaoioa?iaiai ieineiai
ai?oae?th. I?ney e??iaeano?oeoe?? iaoieia?/iiai ina?aaeeo a ia?o?e oac?
iaino?oaeueiiai oeeeeo ?iaeaen aeic??aaiiy oa ea??ii?eiioe/iee ?iaeaen
(EI?) nei??oa aeinyaathoue o?c?ieia?/ii? ii?ie a ii??aiyii? c
iaoe??ioeaie, yeeo i?ie?eiaaii o ae?oa?e oac? iaino?oaeueiiai oeeeeo.
Iaaenie? oeeo?e ea??ii?eiioe/iiai ?iaeaeno ia i?ioyc? oa?i?io
ai?oae?caoe?? ina?aaeeo e??iaeano?oeoe?? a?aeia?aaeathoue i?ioeane
iineeaii? ?aia?aoe?? ai?oae?ioeeo?a, aac caaa?oaiiy iiaiiai
aeeoa?aioe?thaaiiy. ?acii c oei, o ae?iie i?aea?oie A oe? iieacieee aeu?
a ii??aiyii? c i?aea?oiith A.

Ia i?ioyc? aeaio oeaei?a i?ney e??ie?eoaaiiy a?aecia/aii i?aeaeuaiiy
i?iaeoeo?a IIE oa cieaeaiiy iieaciee?a AINC a oea?a?eaeueiiio neeco, ui
iaoiiaeaii aieeaii i?iaeoeo?a e??iaeano?oeoe??. *a?ac 4 oeaei? i?ney
e??ie?eoaaiiy o iaoe??ioie iaio a?oi a?aei?/athoueny cieaeaiiy ??aiy
a?ae?iia?aeen?a a 2,6 ?aca, a ii??aiyii? c ae?oaei oeaeiai
niinoa?aaeaiiy i?ney e??iaeano?oeoe??, oa a 1,3 ?aca ii??aithth/e c
??aiai aei e??ie?eoaaiiy. Oaeaee?noue ia?ieneaeaoe??, eiioeaio?aoe?y AeE
oaeiae cieaeothoueny, aea ia aeinyaathoue ??aiy caei?iaeo ae?iie.

I?e aea/aii? i?noeaaiai noaio AINC i?ney e??ie?eoaaiiy a?aecia/aii
oaiaeaioe?th aei ii?iae?caoe?? ??aiy a?oai?iii? caaacia/aiino?.
Anoaiiaeaii, ui ??-aaiue a?oai?io A /a?ac /ioe?e oeaei? i?ney
e??iaeano?oeoe?? ca?eueoo?oueny a 1,7 ?aca ? iaei a?ae??ciy?oueny a?ae
iieaciee?a caei?iaeo ae?iie (?0,05). ??aaiue a?oai?io A ca?eueoo?oueny
eeoa ia 23%, a ii??aiyii? c iieacieeaie aei e?eoaaiiy.

Aeey ei?aeoe?? i?noeaaeo i?ioean?a IIE/AINC, a oaeiae aea/aiiy oa?i?i?a
?aia?aoeaieo i?ioean?a ia oeeoe? iaoee iaie aoei cai?iiiiiaaii
eiiieaenia e??ie?eoaaiiy c aeei?enoaiiyi iiaiai aioeieneaeaioiiai,
i?ioecaiaeueiiai i?aia?aoo o?io?eacie?io. Caaaeath/e ia oa, ui i?aia?ao
canoiniaoaaany a a?iaeieia?/i?e i?aeoeoe? aia?oa, aoee i?iaaaeai?
iiia?aaei? aeine?aeaeaiiy c a?aeai?o iaea?eueo iioeiaeueii? e?ea?nueei?
oi?ie aeey aeei?enoaiiy i?e e??ie?eoaaii? oiiiaeo caoai?thaaiue oeeee
iaoee. ?aiicaaithth/? aeanoeaino? o?io?eacie?io o aeaeyae? noiiceoi??e,
oaaeaoie oa ?ic/eio canoiniaoaaeenue o eiiieaeniiio e??ie?eoaaii?
iaoe??ioie 5-?, 6-?, 7-? a?oi.

I?e ee?i?ei-eieueiineii?/iiio niinoa?aaeaii? oa?i?ie ai?oae?caoe?? oeeee
iaoee aeyaeeenue a?eueo ei?ioeeie o a?oie oai?eo, ye? aeei?enoiaoaaee
noiiceoi???, ? noaiiaeee — 4,50,4 oeaei?a, a 6-e a?oi? — 6,20,5, a 7-e
a?oi? — 5,60,5 oeaei?a. Noa’?eoeaii iaoe??ioee a?aei?/aee, ui iaea?eueo
c?o/iith e?ea?nueeith oi?iith aoee noiiceoi???.

Aea/aiiy aoaeoeaiino? eiiieaeniiai e??ie?eoaaiiy c aeei?enoaiiyi
noiiceoi??e c o?io?eacie?iii (5-oa a?oia) aoei i?iaaaeaii o ii??aiyii? c
eiiieaeniei e??ie?eoaaiiyi i?e canoinoaaii? noiiceoi??e c iaoeeo?aoeeeii
(3-oy a?oia) oa iae?ieoiaith ie??th (4-oa a?oia). Cacia/ai? i?aia?aoe
canoiniaoaaeenue ia i?ioyc? 10 ae?a i?ney e??iaeano?oeoe??.
Eieueiineii?/i? eiio?ieuei? niinoa?aaeaiiy aeyaeee a?eueo i?enei?aia (ia
2-5 ae?a) caanaiiy yaeu iaa?yeo oa aenoaeaoe?? a cii? e??iiae?ico i?ney
eiiieaenii? oa?ai?? a ii??aiyii? c iiiie??ioa?ai??th. Oa?i?ie
a?aeoi?aiaiiy no?oio oa i?ioean ai?oae?caoe?? iiaa?oi? oeeee iaoee i?ney
e??iaeano?oeoe?? a?aeaoaaeenue nei??oa o a?oiao iaoe??ioie, yeei aoei
i?iaaaeaia eiiieaenia e??io??o?a?/ia e?eoaaiiy o oie?eoe?iia?e oac?
iaino?oaeueiiai oeeeeo (oaae.1).

Oaaeeoey 1.

Aeeiaieea no?ie?a caaa?oaiiy ai?oae?caoe?? (a oeaeiyo) i?ney
e??ie?eoaaiiy a ??ci? oace iaino?oaeueiiai oeeeeo

o iaoe??ioie 2-5 a?oi

A?oie

No?iee

niinoa?aae.

2

3

4

5AAAAAAAAaan.%aan.%aan.%aan.%aan.%aan.%aan.%aan.%3-4
oeaeiy33,379,6215,4211,818,416,21630,83560,35-6
oeaei?a88,73041,117,7741,2433,31062,53057,62034,57-8
oeaei?a6267,43142,5861,5635,2541,742511,923,5> 8
oeaei?a66,511,415,9Na?aaei? no?iee
ai?oae?caoe??7,60,2**6,30,3*6,90,6**6,30,3**6,40,6**5,90,4**5,10,23,90,1
Anueiai7969111610154757

I?ei?oea: neiaie * iicia/a?, ui ?acoeueoao ? noaoenoe/ii aeinoia??iei
(?<0,05) i?e ii??aiyii? iieaciee?a a i?aea?oiao A e A a iaaeao iaei??? a?oie; neiaie ** iicia/a?,. ui ?acoeueoao aeinoia??iee (?<0,05) i?e ii??aiyii? c iieacieeaie i’yoi? a?oie. O a?oi? ae?iie i?ney canoinoaaiiy o?io?eacie?io oa?i?ie ?aia?aoe?? iiaa?oi? oeeee iaoee i?ney e??iaeano?oeoe?? noaoenoe/ii aeinoia??ii a?ae??ciyeenue a?ae iieaciee?a ?ioeo a?oi. I?e eieueiineii?? anoaiiaeaii, ui i?ney eiiieaeniiai e??ie?eoaaiiy c aeei?enoaiiyi o?io?eacie?io no?oi aoa a?eee, aeanoe/iee, naiino?eii a?aeae?eyany ia 7-10-oo aeiao i?ney e??iaieeao. I?ae no?oiii aeyaeyeanue a?aioeyoe?eia oeaieia c ?ioaineaiith e?aeiaith ?aaaia?aoe??th ai?oae?th. Noaeeiiee iaethiie a cii? ?aaaia?aoe?? aoa yne?aaei, c iiceoeaiith ?aaeoe??th ia ?ic/ei ioeoo. Ia ae?oaiio oeaei? i?ney e??iao?o/aiiy ii ia?eoa??? ina?aaeeo e??iaeano?oeoe?? iaeaea o an?o ae?iie, ye? io?eiaee a eiiieaeniiio e?eoaaii? o?io?eacie?i, a?aecia/ai? ae?eyiee aaaaoioa?iaiai ieineiai ai?oae?th. I?ioean caai?iiy ina?aaeeo aeano?oeoe?? o oe?e a?oi? noi?iaiaeaeoaaany iaio yne?aaeie ne?aeaie caiaeaiiy: ciaiooaaany iaa?ye oeaiei oa aenoaeaoe?y, e?ioi?ay i?eieiyeanue ia 2-3 oeaei? oaeaeoa a ii??aiyii? c ?ioeie a?oiaie niinoa?aaeaiiy. Na?aaei? oa?i?ie ai?oae?caoe?? noaiiaeee: a o?ao?e a?oi? - 6,50,3 oeaeiy; a /aoaa?o?e - 6,203; a i’yo?e - 4,50,4 oeaeiy, a i?ney iiiie??ie?eoaaiiy aiie neeaaeaee - 6,90,1 oeaeiy (aeea.oaae.1). Oeeoiii?oieia?/ieie aeine?aeaeaiiyie anoaiiaeaii i?enei?aiiy i?ioean?a i?ie?oa?aoe?? oa ?aaaia?aoe?? a ai?oae?? oeeee iaoee i?ney eiiieaeniiai e??ie?eoaaiiy, iniaeeai i?e canoinoaaii? o?io?eacie?io. C 7-? aeiae niinoa?aaeaiiy aeyaeyeinue ca?eueoaiiy e?eueeino? aacaeueieo ee?oei o i’yo?e a?oi?, aea i?ecia/aany o?io?eacie?i, aei 23% oa ci?uaiiy ?iaeaeno aeic??aaiiy ae?ai. C?inoaiiy aacaeueieo ee?oei a?aecia/aii i?ney aeei?enoaiiy iaoeeo?aoeeeo aei 17% oa iae?ieoiai? ie?? aei 10%, ui a aeae?eueea ?ac?a ia?aaeuo? iieacieee ae?iie, ye? io?eiaee iiiie??ie?eoaaiiy, aea ??aaiue aacaeueieo ee?oei ia oeae ia??iae noaiiaea 2%. Ca?eueoaia e?euee?noue aacaeueieo ee?oei ia i?ioyc? ia?oeo oeaei?a e?eoaaiiy iia'ycaia c? noeioethth/ei aieeaii i?aia?ao?a ia i?ioeane i?ie?oa?aoe?? ee?oei (Iaco? ?.A. oa ?io?, 1997-1998). Oeeoieia?/i? ?acoeueoaoe na?ae/aoue i?i ia?aoioiaai?noue i?iaaaeaiiy iaaeeeaiaioicii? oa?ai?? i?ney e??ie?eoaaiiy. Noeioeth/ee aieea o?io?eacie?io ia ai?oae?aeuei? ee?oeie aoa aeuei, i?ae o iaoeeo?aoeeeo oa iae?ieoiai? ie??. Cia/i? ci?ie a?aecia/ai? a iiioeyoe?? e?ioioeeo?a o iaceao c aiaeioea?a?eno i?ioyaii anueiai ia??iaeo niinoa?aaeaiiy. O a?oi? iaoe??ioie, aea canoiniaaii o?io?eacie?i, a?yaeaii i?aeaeuaiee ??aaiue aaeeeeo e?ioioeeo?a, a ?ioeo a?oiao niinoa?aaeaiiy /ano?oa niinoa??aaee iayai?noue iaeeo oi?i e?ioioeeo?a. A iaceao c iiaa?oi? oeeee iaoee, ia oii? canoinoaaiiy o?io?eacie?io, yaeua eaeeioeeoico oa oaaioeeoa?ia aeoeai?noue eaeeioeeo?a aoee aeu?, i?ae a ?ioeo a?oiao, ui a iiaeaeueoiio (ia 28-42 aeiao) noi?iaiaeaeoaaeinue iiyaith iaee/ie Aeiaea?eaeia oa iace?a - nooiaith /enoioe i?oae. I?e i?iaaaeaii? iiiie??ioa?ai?? ia oeae no?ie a iaceao c iiaa?oi? oeeee iaoee oo?eio?oueny eaeeioeeoic oa -V nooiai? /enoioe i?oae. O iaoe??ioie 3-?, 4-? oa 5-? a?oi, ye? io?eioaaee eiiieaenio e??ioa?ai?th, niinoa??aaeanue a?eueo oaeaeea ii?iae?caoe?y i?noeaaeo i?ioean?a IIE ? c?inoaiiy ??aiy iioaioe?aeo AINC, o ii??aiyii? c ae?oaith a?oiith, aea i?iaiaeeee iiiie??ie?eoaaiiy. Nooo?aa ??cieoey iieaciee?a IIE/AINC a oea?a?eaeueiiio neec? anoaiiaeaia i?ae a?oiaie, a yeeo aeei?enoiaoaaeenue iaoeeo?aoeee (3-y a?oia), iae?ieoiaa ie?y (4-oa a?oia) oa o?io?eacie?i (5-oa a?oia). Oae ??aaiue AIE/ie aaea /a?ac 2 oeaei? i?ney e??ie?eoaaiiy a 5-e a?oi? niinoa?aaeaiiy aoa o 1,5 ?aca ieae/ee, i?ae o o?ao?e a?oi?, oa a 1,7 ieae/ee i?ae o /aoaa?o?e a?oi?. Iieacieee ae??iiaeo eaoii?a (AeE) oaeaeoa ii?iae?coaaeenue a 4-e oa 5-e a?oiao, i?ae o iaoe??ioie o?aouei? a?oie, aea aeei?enoiaoaaee iaoeeo?aoeee. Aea/aiiy aeeiai?ee iieaciee?a aioeieneaeaioii? nenoaie caoenoo a oea?a?eaeueiiio neec? iieacaei, ui ??aaiue eaoaeace (EO) a a?oiao, aea canoiniaaii o?io?eacie?i oa iae?ieoiao ie?th, i?aeaeuo?oueny aeinoia??ii oaeaeoa, i?ae o iaoe??ioie, ye? aeei?enoiaoaaee iaoeeo?aoeee. ??aaiue a?oai?io A oaeaeoa ii?iae?coaaany i?e canoinoaaii? o?io?eacie?io aei 2,90,3 ieiieue/e, oa iaoeeo?aoeeeo aei 2,20,2 ieiieue/e. I?e aeei?enoaii? noiiceoi??e c iae?ieoiaith ie??th a?i noaiiaea 1,50,1 ieiieue/e, a i?ney i?iaaaeaiiy iiiie??ie?eoaaiiy - 1,20,3 ieiieue/e.Iieacieee ??aiy a?oai?io A a oea?a?eaeueiiio neec? ae?iie /a?ac i?nyoeue i?ney eiiieaeniiai e??ie?eoaaiiy noaoenoe/ii aeinoia??ii ia a?ae??ciyeenue a?ae iieaciee?a a?oie caei?iaeo ae?iie. Aea/aiiy caaaeueieo i?ioean?a IIE/AINC o ne?iaaooe? e?ia? iaoe??ioie c oiiiaeie caoai?thaaiiyie oeeee iaoee ia aeyaeei noaoenoe/ii aeinoia??ii? ??cieoe? iieaciee?a o ii??aiyii? c? caei?iaeie ae?ieaie, aea a?aecia/aia oaiaeaioe?y aei ?o c?inoaiiy. I?iaaaeaiiy e??ie?eoaaiiy ni?eyei ii?iae?caoe?? ??aiy iiea-ciee?a aioeieneaeaioii? nenoaie caoenoo ? noaiiaeaiith ??aiiaaae i?ae iieacieeaie IIE/AINC. A?eueoa aoaeoeai?noue a ii?iae?caoe?? i?ioean?a ia?ieneaeaoe?? aoea io?eiaia i?e canoinoaaii? a eiiieaeniiio e?eoaaii? o?io?eacie?io. *a?ac 4-6 oeaei?a i?ney eiiieaeniiai e??ie?eoaaiiy o a?eueoino? ae?iie a?aecia/aeany ii?iae?caoe?y i?ioean?a aeic??aaiiy ai?oae?th a?aeiia?aeii o?c?ieia?/i?e oac? iaino?oaeueiiai oeeeeo. A a?oi? ae?iie i?ney ?cieueiaaiiai e??iaieeao oae? i?ioeane niinoa??aaeeny eeoa ia 8-io oeaei? (aeea. oaae.1). I?e iiaeeaeaiiio aea/aii? oeeoia?ai iace?a-a?aeaeoe?a c iiaa?oi? oeeee iaoee oa c aiaeioea?a?eno o an?o a?oiao niinoa?aaeaiiy aeyaeai? ae?iee (2a?.-18; 3a?.-3; 4a?.-3; 5a?.-4 iaoe??ioee), o yeeo a iaceao c iiaa?oi? oeeee iaoee e?euee?noue aacaeueieo ee?oei ia?aaeuoaaea 25%, a a iaceao c aiaeioea?a?eno aeyaeyeiny a?eueoa 20% aaeeeeo e?ioioeeo?a. O a?eueoino? oeeo ae?iie /a?ac 6-12 i?nyoe?a aoee aeyaeai? ?aoeeaeeae oiiiaeo caoai?thaaiue oeeee iaoee (iae.1). A ia?o? 6 i?nyoe?a niinoa?aaeaiiy i?ney e??ie?eoaaiiy /anoioa oneeaaeiaiue (iaiiaia ai?oae?caoe?y, aie?nia iaoeyoe?y, caaino?aiiy o?ii?/ieo caiaeueieo i?ioean?a, ii?ooaiiy iaino?oaeueiiai oeeeeo) aoea a 1,5 ?aca iaioith o iaoe??ioie, yeeo i?ie?eiaaii o oie?eoe?iia?e oac? iaino?oaeueiiai oeeeeo, a ii??aiyii? c ae?ieaie, ui io?eiaee e?eoaaiiy o ethoa?iia?e oac?. I?ecia/aiiy aioeieneaeaioieo i?aia?ao?a i?ney e??iaeano?oeoe?? ciaioeei e?euee?noue oneeaaeiaiue - i?e aeei?enoaii? noiiceoi??e o?io?eacie?io a aeaa ?ace, iaoeeo?aoeeeo - a 1,2 ?aca, iae?ieoiai? ie?? - a 1,4 ?aca a ii??aiyii? c iiiie??ioa?ai??th (iae.1). *a?ac ??e niinoa?aaeaiiy a a?oi? i?ney iiiie??ioa?ai?? ?aoeeaeeae oiiiaeo caoai?thaaiue oeeee iaoee aeyaeai? a 9,9% ae?iie (iae.1), i?ney eiiieaeniiai e?eoaaiiy c iaoeeo?aoeeeii- o 8%, c iae?ieoiaith ie??th- o 9,1%, a i?e i?ecia/aii? o?io?eacie?io- o 3,6% iaoe??ioie (?0,05). wmetafile8? ???? ???????? ???????yyy???????????? ???? ????'yy??/???????????????????????????????AAA?AUeA?¦E??  """)))UUUMMMBBB999y|?yPPOe?“IiyiOeAEccOe©Iae.1. *anoioa oneeaaeiaiue ? ?aoeeaeea?a (a %) i?ney iiiie??ioa?ai?? (2 a?.) ? eiiieaeniiai e?eoaaiiy c i?ecia/aiiyi ??cieo aioeieneaeaioieo i?aia?ao?a (3 a?.-5 a?.). Noai iaino?oaeueii? oa ?ai?iaeoeoeaii? ooieoe?? i?inoaaeaii o 232 ae?iie ia i?ioyc? aeaio ?ie?a i?ney i?iaaaeaiiai e?eoaaiiy. A?aeoeeaiue iaino?oaeueiiai oeeeeo o ae?iie a?ae o?c?ieia?/iiai eiai noaio aei e??ie?eoaaiiy, ia a?aecia/aii. 144 ae?iee (62,1%) caiia?aaee aaa?oiino?. O 68 ae?iie (29,3%), o oiio /ene? a 10 ?c 29 iaoe??ioie, o yeeo aei e??ie?eoaaiiy aoea ae?aaiinoiaaia iaie?aei?noue iac'yniaaiiai aaiaco, ianoaea aaa?oi?noue i?ney i?iaaaeaiiai eiiieaeniiai e??ie?eoaaiiy. AENIIAEE 1. E??iaeano?oeoe?th oiiiaeo caoai?thaaiue oeeee iaoee iaiao?aeii i?iaiaeeoe a ?aii?e oie?eoe?iia?e oac? iaino?oaeueiiai oeeeeo, ui caaacia/o? o?c?ieia?/ia i?io?eaiiy ?aia?aoeaieo i?ioean?a, yea oa?aeoa?eco?oueny iineeaiith i?ie?oa?aoe??th ai?oae?aeueieo ee?oei, oaeaeoei a?aeoi?aiaiiyi no?oio ia 3-4 aeiae oa i?enei?aiei a?aeiiaeaiiyi no?oeoo?e ai?oae?th oeeee iaoee ia 1,5 oeaei? a ii??aiyii? c ?acoeueoaoaie e?eoaaiiy o ethoa?iia?e oac?. 2. Oiiia? caoai?thaaiiy oeeee iaoee i?io?eathoue i?e aeoeaaoe?? ia?aaaaeii i?noeaaeo i?ioean?a ia?ieneaeaoe?? oa aeniaaeaii? aioeieneaeaioii? nenoaie caoenoo. Ci?ie noaio i?noeaai? nenoaie IIE/AINC a oea?a?eaeueiiio neec?, ia a?aei?io a?ae oeeo ia?aiao??a o e?ia?, ? ?ioi?iaoeaieie iieacieeaie ?icaeoeo caoai?thaaiiy oa a?aeaoaeiae ai?oae?aeueiiai oa?o oeeee iaoee i?ney e??iaeano?oeoe??. 3. Eiiieaenia oa?ai?y c aeei?enoaiiyi aioeieneaeaioieo i?aia?ao?a i?ney e??iaeano?oeoe?? ? iioeiaeueiei iaoiaeii e?eoaaiiy oiiiaeo caoai?thaaiue, yeee aeinoia??ii i?enei?th? oa?i?ie ?aaaia?aoe?? oeeee iaoee oa iie?auo? ?acoeueoaoe e?eoaaiiy. Iaea?eueo aoaeoeaiei i?aia?aoii i?e eiiieaeni?e oa?ai?? ? o?io?eacie?i. 4. Canoinoaaiiy o?io?eacie?io o eiiieaeniiio e?eoaaii? oiiiaeo caoai?thaaiue oeeee iaoee ? iaoiaaiaoe/ii iaa?oioiaaiei, ui i?eaiaeeoue aei ii?iae?caoe?? i?ioean?a IIE/AINC, nei?i/o? oa?i?ie ai?oae?caoe?? oeeee iaoee ia 1,5- 2 oeaei?, ciaioo? e?euee?noue oneeaaeiaiue a 2 ?ace ? /enei ?aoeeaeea?a a 2,8 ?aca, a ii??aiyii? c iiiie??ioa?ai??th. Aeey aeei?enoaiiy a a?iaeieia?? iaea?eueo aoaeoeaiith oa c?o/iith e?ea?nueeith oi?iith i?aia?aoo ? noiiceoi???. 5. Oeeoiii?oieia?/i? aeine?aeaeaiiy aeicaieythoue i?iaiicoaaoe oneeaaeiaiiy i?neyiia?aoe?eiiai ia??iaeo oa ?aoeeaeeae oiiiaeo caoai?thaaiue oeeee iaoee. I?iaiinoe/ieie e?eoa??yie iiaeeeaeo oneeaaeiaiue ? ciaoiaeaeaiiy a iaceao c iiaa?oi? oeeee iaoee a?eueoa 25% aacaeueieo ai?oae?aeueieo ee?oei, a c oea?a?eaeueiiai eaiaeo a?eueoa 20% aaeeeeo e?ioioeeo?a /a?ac 28-42 aeiae i?ney e??ie?eoaaiiy. 6. Eiiieaeniee e??io??o?a?/iee niin?a e?eoaaiiy ? aoaeoeaiei iaoiaeii cieaeaiiy ?aoeeaeea?a oiiiaeo caoai?thaaiue oeeee iaoee. ?aoeeaeeae caoai?thaaiue cono??/aeenue c iaioith /anoioith i?ney eiiieaeniiai e??ie?eoaaiiy ? /a?ac ??e niinoa??aaeenue i?e aeei?enoaii? o?io?eacie?io o - 3,6% aeiaaee?a, iaoeeo?aoeeeo - 8%, iae?ieoiai? ie?? - 9,1%, a i?ney iiiie??ie?eoaaiiy o 9,9% aeiaaee?a. I?aeoe/i? ?aeiiaiaeaoe??. 1. E??ie?eoaaiiy ae?iie c oiiiaeie caoai?thaaiiyie oeeee iaoee aeioe?eueii i?iaiaeeoe a ?aii?e oie?eoe?iia?e oac? iaino?oaeueiiai oeeeeo. 2. Aeey i?aeaeuaiiy aoaeoeaiino? e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee iaiao?aeii canoiniaoaaoe eiiieaeniee iaoiae e??io??o?a?/iiai e?eoaaiiy c i?noeaaei aeei?enoaiiyi i?ioecaiaeueiiai oa aioeieneaeaioiiai i?aia?aoo o?io?eacie?io o aeaeyae? ?io?aaaa?iaeueieo noiiceoi???a ii 0,25 a ae?th/i? ?a/iaeie iaeei ?ac ia aeiao, ia i?ioyc? 10 ae?a i?ney e??iaeano?oeoe??. 3. C iaoith ?aiiuei? ae?aaiinoeee oneeaaeiaiue oa ?aoeeaeea?a oiiiaeo caoai?thaaiue oeeee iaoee iaiao?aeii i?iaiaeeoe ne?ei?iaiaa oeeoieia?/ia aeine?aeaeaiiy c i?ae?aooaaiiyi aacaeueieo ai?oae?aeueieo ee?oei a iaceao c iiaa?oi? oeeee iaoee oa e?eueeino? aaeeeeo e?ioioeeo?a a iaceao oea?a?eaeueiiai eaiaeo ia 28-42 aeiao i?ney e??ie?eoaaiiy. Oeeoieia?/ieie e?eoa??yie i?iaiicoaaiiy iiaeeeaiai ?icaeoeo ?aoeeaeea?a ? aeyaeaiiy a iaceao aei 25% aacaeueieo ai?oae?aeueieo ee?oei oa 20% aaeeeeo e?ioioeeo?a. 4. Oa?i?i aeeniaina?iiai iaaeyaeo ca iaoe?aioeaie i?ney eiiieaeniiai e??io??o?a?/iiai e?eoaaiiy iiaeiai neeaaeaoe: aeaa i?nyoe? i?e a?aenooiino? ne?ei?iaiaeo eieueiioeeoieia?/ieo iciae ?aoeeaeeao ? iaeei ??e – i?e iayaiino? oeeo iciae. 5. Aeei?enoaiiy ia?iaaceaiiai iaoiaeo aea/aiiy i?noeaaeo i?ioean?a IIE/AINC (a oea?a?eaeueiiio neec?) o ae?iie ? a??ia?aeiei i?iaiinoe/iei oanoii ?icaeoeo iaoieia?/ieo i?ioean?a ia oeeoe? iaoee oa ioe?iee aoaeoeaiino? e?eoaaiiy. NIENIE ?IA?O, IIOAE?EIAAIEO CA OAIITH AeENA?OAOe?? 1.Aaaeeaa I.N., Aieioeia I.I. Aei ieoaiiy aecia/aiiy no?ieo ?iae?a //IAA.-1980.-?2.-N.37-38. 2.Aieioeia I.I., AEa?eeo A.A, ?aaaiueei I.I. Aeina?ae ?iaioe uiaei cieaeaiiy a?iaeieia?/ii? caoai?thaaiino? na?aae ?ia?oieoeue AO "AaoiCAC" //IAA.-1997.- ?5.-N.87-88. 3.Aieioeia I.I. Iioeiecaoeey e?eioe?o?ae/aneiai ea/aiey aieueiuo n oiiiauie caaieaaaieyie oaeee iaoee //I?iae.e?eiaeie.-1998.- ?2.-N.60-63. 4.Aieioeia I.I., Eooeaiei I.N. Eiiieaeniia e?eioe?o?ae/aneia ea/aiea oiiiauo caaieaaaiee i?e iaieeeiiaae?oniii eioeoee?iaaiee //I?iae. E?eiaeie.-1998.- ?2.-N.64-67. 5.Aieioeia I.I., Iaco? E.A., Eo/a?aiei E.E. I?eiaiaiea oeio?eacieeia a eiiieaeniie oa?aiee oiiiauo caaieaaaiee oaeee iaoee //A?ni. A?eioea?e?anueeiai aea?aeaaiiai aa?a?iiai oi?aa?neoaoo.-1998.-Aei.6.-*.2.-N.111-114. 6.Ieiyaeei I.?., Noaoe A.A., Eo/a?aiei E.E., Noaoe ?.A., Aieioeia I.I. Enneaaeiaaiea aaca?aaeiinoe e niaoeeoe/aneie aeoeaiinoe noiiiceoi?eaa n oeio?eacieeiii //Ca.iaoe.no."Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee oa i?aeoeee.-Caii??aeaey,1998.-Aei..-O..-N.64-67. 7.Aieioeia I.I, Eooeaiei I.N., Oeeaaaa O.A.,Ninoiyiea i?ioeannia ia?aeeniiai ieeneaiey eeieaeia e aioeieneaeaioiie nenoaiu o aieueiuo n oiiiauie caaieaaaieyie oaeee iaoee // Ca.iaoe.no."Aeooaeuei? ieoaiiy oa?iaoeaaoe/ii? oa iaaee/ii? iaoee oa i?aeoeee.-Caii??aeaey,1999.-Aei..-O..-N.162-168. 8.Aieioeia I.I. N?aaieoaeueiay ioeaiea aeeaoa?iioe?o?ae/aneiai e e?eioe?o?ae/aneiai ea/aiey oiiiauo caaieaaaiee oaeee iaoee: Na.iao/.o?.-Caii?iaeuea: ??A"I?a?oa-TH.A.",1996.-N.9-10. 9.Aieioeia I.I. Yooaeoeaiinoue ea/aiey aieueiuo yiaeiiao?eicii oaeee iaoee e?eioe?o?ae/aneei iaoiaeii //Aeooaeueiua aii?inu aeooa?noaa e aeiaeieiaee.-Caii?iaeuea: OeIEO CAIO.-1996.-N.20-21. 10.Aieioeia I.I. E?eoaaiiy oai?eo aiaeiiao??icii oeeee iaoee e??io??o?a?/iei iaoiaeii a ae?ii/?e eiinoeueoaoe?? //Oac.aeii. O-ai c'?caeo aeooa??a-a?iaeieia?a Oe?a?ie.-Iaeana, 1996.-N.123. 11.Aieioeia I.I. E?eiaaiiue iaoiae ea/aiey ineiaeiaiee aeeaoa?iieiaaoeyoeee oaeee iaoee //Iaoa?. aeii. iaoe.eiio."Aeooaeuei? ieoaiiy oai?aoe/ii? oa ee?i?/ii? iaaeeoeeie ia no/aniiio ??ai?". –Iieoaaa, 1996.-N.66-67. 12.Aieioei I.A., Iaeuaeaa A.A., Iaco? E.A, Aece? A.A., Aieioeia I.I., Aacoaeue A.N., Aeiaauo I.A., Iauaiei N.I., Oieiaeiue A.A., Iina/aiei ?.A. Ia?aniaeoeau i?eiaiaiey iiaiai eiioiio?iiiiai i?aia?aoa -oeio?eacieeia //Ca.oac. 1-ai Iaoe?iiaeueiiai eiia?ano Oe?a?ie c ?ioiieia??, aea?aieia?? oa ?ioii?aaa?e?oaoe??.-Aeoooa, 1998.-N.42. 13.Aieioeia I.I., Eooeaiei I.N. I?eiaiaiea oeio?eacieeia a eiiieaeniii ea/aiee iaieeeiiaae?oniie eioaeoeee oaeee iaoee //Iaoa?. iaaeaeoia?iaeiiai eiia?anna “Aeooaeueiua aii?inu eioaeoieiaee a aeooa?noaa e aeiaeieiaee”.-Aeiiaoee, 1998.-N.1-2. 14. Eooeaiei I.N., Aieioeia I.I. Aeeyiea oeio?eacieeia ia i?ioeannu naiaiaeii?aaeeeaeueiiai ieeneaiey a oaeea iaoee iinea e?eiea/aiey //Na.iao/i.o?. “Aeooaeueiua aii?inu ?ai?iaeoeoieiaee e e?eiiaaeeoeeiu”.-Oa?ueeia, 1998.-N.150-155. AIIOAOe?ss Aieioeia I.I. Oeyoe i?aeaeuaiiy aoaeoeaiino? e??io??o?a?/iiai e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee. -?oeiien. Aeena?oaoe?y ia caeiaoooy iaoeiaiai nooiaiy eaiaeeaeaoa iaaee/ieo iaoe ca niaoe?ae?i?noth 14.01.01 - aeooa?noai ? a?iaeieia?y.-Oa?e?anueeee aea?aeaaiee iaaee/iee oi?aa?neoao, Oa?e?a,1999. Aeena?oaoe?y i?enay/aia ?ic?iaoe? iaoiae?a i?aeaeuaiiy aoaeoeaiino? e??io??o?a?/iiai e?eoaaiiy oiiiaeo caoai?thaaiue oeeee iaoee. Aeey eiiieaeniiai e??io??o?a?/iiai e?eoaaiiy aoei canoiniaaii iiaee aioeieneaeaio o?io?eacie?i. Ee?i?/ieie, eieueiineii?/ieie oa eaai?aoi?ieie iaoiaeaie aeiaaaeaii, ui i?iaaaeaiiy eiiieaeniiai e??io??o?a?/iiai e?eoaaiiy ii?iae?co? i?noeaa? i?ioeane IIE/AINC a oea?a?eaeueiiio neec?, i?enei?th? ?aaaia?aoe?th ai?oae?th oeeee iaoee oa oa?i?ie ai?oae?caoe??. Aeei?enoaiiy o?io?eacie?io iie?ioeei ?acoeueoaoe e??io??o?a?/iiai e?eoaaiiy, ui ciaioeei e?euee?noue oneeaaeiaiue o aeaa ?ace oa ?aoeeaeea?a oiiiaeo caoai?thaaiue oeeee iaoee a 2.8 ?aca. Eeth/ia? neiaa: oiiia? caoai?thaaiiy oeeee iaoee, eiiieaenia e??ie?eoaaiiy, ?aia?aoeai? i?ioeane, aioeieneaeaioe, o?io?eacie?i. AIIIOAOeEss Aieioeia I.I. Iooe iiauoaiey yooaeoeaiinoe e?eioe?o?ae/aneiai ea/aiey oiiiauo caaieaaaiee oaeee iaoee.- ?oeiienue. Aeenna?oaoeey ia nieneaiea iao/iie noaiaie eaiaeeaeaoa iaaeeoeeineeo iaoe ii niaoeeaeueiinoe 14.00.01 - aeooa?noai e aeiaeieiaey. -Oa?ueeianeee ainoaea?noaaiiue iaaeeoeeineee oieaa?neoao, a.Oa?ueeia,1999. Aeenna?oaoeey iinayuaia ?ac?aaioea iaoiaeia iiauoaiey yooaeoeaiinoe e?eioe?o?ae/aneiai ea/aiey oiiiauo caaieaaaiee oaeee iaoee. Aeey eiiieaeniiai e?eiea/aiey i?aaeeiaeai iiaue aioeieneaeaio - oeio?eacieei. Eeeie/aneeie, eieueiineiie/aneeie e eaai?aoi?iuie iaoiaeaie aeieacaii, /oi i?iaaaeaiea eiiieaeniiai ea/aiey i?eaiaeeo e ii?iaeecaoeee ianoiuo i?ioeannia IIE/AINC a oea?aeeaeueiie neece, oneeeaaao i?ioeannu ?aaaia?aoeee e onei?yao n?iee yieoaeecaoeee. I?eiaiaiea oeio?eacieeia oeo/oaao ?acoeueoaou e?eioe?o?ae/aneiai ea/aiey, oiaiueoaao /enei ineiaeiaiee a 2 ?aca e ?aoeeaeeaia a 2,8 ?aca. Eeth/aaua neiaa: oiiiaua caaieaaaiey oaeee iaoee, eiiieaeniia e?eiea/aiea, ?aia?aoeaiua i?ioeannu, aioeieneaeaiou, oeio?eacieei. Abstract Voloshyna N.M. Raising the efficacy of cryosurgery methods for the treatment of cervix uteri background diseases, - Manuscript. Thesis for a Candidate of Medical Science degree obtaining in speciality 14.01.01 - Obstetrics and Gynecology - Kharkov State Medical Academy Kharkov, 1999. The manuscript is devoted to the actual problem of improving cryosurgery treatment of cervix uteri background diseases. That will quicken the process of cervix uteri regeneration, decrease the number of cases with complications and relapses. There has been elaborated a new complex method for cryosurgery treatment of cervix uteri background diseases. It is based on the usage of a new home-made medicine Thiotriazolinum. A new medical form of Thiotriazolinum - suppositoria - for the usage in gynecology was created. The thesis contains the results of clinical, colposcopical, cytological, histological and biochemical methods of investigation. 393 women with cervix uteri background diseases were under observation. The control group was composed of 30 women without pathology in cervix uteri. The efficacy of the complex cryosurgery method with thiotriazolinum was studied in comparison with that on using Methyluracil, Oleum Hippopheae and monocryotherapy. It was proved by the test that cryodestruction as a method for the treatment of cervix uteri background diseases is advisable in early folliculin phase. That will provide a more physiological, natural character of cervix uteri repair after the operation. Cervix uteri background diseases are accompanied by the activation of general and local peroxydation of lipids and disbalance in antyioxydation defense system. The complex cryosurgery method using the antioxydant thiotriazolinum has a pathogenic base, thus enabling the correction of local abnormal peroxydation, simulation of regeneration and quicken the epithelization of cervix uteri after cryodestruction. With the use of cytomorphological methods was established the fact of acceleration of proliferation processes and regeneration of epithelium of cervix uteri after complex cryosurgery treatment. This fact connected with the stimulating influence of thiotriazolinum on proliferation processes. In the surface smears of cervix uteri with the use thiotriazolinum the leucocytosis and phagocyte activity were increased in comparison with the other groups. It was hereinafter accompanied by occurrence of Doderlane bacillus and smears ? - ?? of a degree of cleanliness of vagina. Usage of thiotriazolinum in the complex method decreases the incidence of complication after cryosurgery by 2 times and that of relapses by 2.8 times. The relapses of disease decreased with the use of thiotriazolinum by 3,6 percent, Methyluracil - 8 percent, Oleum Hippopheae - 9,1 percent in comparison with monocryotherapy (9,9 percent). The state of menstrual and reproductive functions during two years were investigated at 232 women. The deviations of menstrual cycle at the women in comparison with the same before cryotherapy were not observed. The 144 of women (62,1 percent) were protected from pregnancy by various methods. At 68 (29,3 percent) of women, including the 10 of 29 observed concerning sterility, become pregnant. This fact testifies the restoration of reproductive function after complex cryotherapy. Cytological analysis is very effective for the observation of cervix uteri repair after cryodestruction. The going number of basal cells on the cervix uteri surface and appearance of large lymphocytes in smears taken from endocervix serves as a screening - test for findings the recurrence after cryodestruction which demands a long-time observation of this group of patients. Thus, the results of research show, that the realisation complex cryotherapy, results in restoration of local peroxidation processes in endocervix serves accelerates the reparative processes in epithelium of cervix uteri, reduces the terms of regeneration after cryodestruction, reduces the number of complications and relapses of background diseases in cervix uteri. Hereinafter promotes the menstrual and reproductive functions of the women. The significant reduction of number of complications and relapses of background diseases of cervix uteri after complex cryotherapy allows to recommend this method in practice of female consultations and gynecological branches of clinics. Keywords: background diseases of cervix uteri, cryotreatment, restorative processes, antioxydants, thiotriazolinum.

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